Results of Job: search_a10d8d4b-5743-49d4-8c42-f584e3f6a993

Query Target Key Target Name Description P-Value MaxTC

Rimegepant

CALRL_HUMAN CALCRL Calcitonin gene-related peptide type 1 receptor 1.246e-111 1.00
PLD1_RAT Pld1 Phospholipase D1 2.359e-53 0.32
PLD1_HUMAN PLD1 Phospholipase D1 7.485e-42 0.33
PLD2_HUMAN PLD2 Phospholipase D2 4.911e-41 0.33
CALCA_RAT Calca Calcitonin gene-related peptide 1 1.649e-40 0.51
HRH3_CAVPO HRH3 Histamine H3 receptor 7.8e-10 0.34
V1AR_MOUSE Avpr1a Vasopressin V1a receptor 3.292e-06 0.29
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 9.766e-06 0.36

Betulinic_Acid

DPOLB_RAT Polb DNA polymerase beta 1.131e-63 1.00
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 1.78e-25 1.00
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 2.357e-17 1.00
Q9YQ12_9HIV1 protease Protease 7.147e-06 1.00
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 0.0005651 1.00
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 0.0006262 1.00
Q77YG1_9HIV1 gag Gag polyprotein 5.585e-81 0.67
CD81_HUMAN CD81 CD81 antigen 4.556e-46 0.37
DHI2_RAT Hsd11b2 Corticosteroid 11-beta-dehydrogenase isozyme 2 3.092e-44 0.35
Q43445_SOYBN Methyltransferase 6.705e-36 0.28
PA2A1_ECHCA Acidic phospholipase A2 EC-I 1.78e-34 0.43
PA2B1_NAJME Basic phospholipase A2 1 1.78e-34 0.43
PA2BA_PROFL Basic phospholipase A2 PLA-A 1.78e-34 0.43
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 5.786e-27 0.53
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 1.875e-23 0.72
PTN2_HUMAN PTPN2 Tyrosine-protein phosphatase non-receptor type 2 2.073e-22 0.43
IL1B_HUMAN IL1B Interleukin-1 beta 1.122e-17 0.34
TF65_HUMAN RELA Transcription factor p65 1.11e-16 0.75
POL_HV1H2 gag-pol Gag-Pol polyprotein 5.551e-16 0.67
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 5.107e-15 0.35
TF_HUMAN F3 Tissue factor 4.314e-13 0.68
CAH2_BOVIN CA2 Carbonic anhydrase 2 6.966e-10 0.60
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 4.45e-09 0.36
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 7.407e-08 0.32
DHI1_MOUSE Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 9.508e-08 0.46
DPOLB_HUMAN POLB DNA polymerase beta 4.01e-07 0.43
EST2_HUMAN CES2 Cocaine esterase 4.899e-07 0.36
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.047e-06 0.43

Copanlisib

PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5.573e-21 1.00
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 0.0001119 1.00
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0.002681 1.00
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 0.008401 1.00
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 1.319e-56 0.34
HGF_HUMAN HGF Hepatocyte growth factor 3.098e-40 0.31
SL9A1_RAT Slc9a1 Sodium/hydrogen exchanger 1 7.806e-37 0.35
SCRB1_HUMAN SCARB1 Scavenger receptor class B member 1 4.953e-28 0.37
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 3.145e-27 0.31
AUKBA_XENLA aurkb-a Aurora kinase B-A 8.731e-25 0.40
IMA1_HUMAN KPNA2 Importin subunit alpha-1 4.633e-23 0.28
RENI_CALJA REN Renin 1.307e-21 0.37
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 3.095e-20 0.36
PIR_HUMAN PIR Pirin 4.906e-20 0.32
MK14_MOUSE Mapk14 Mitogen-activated protein kinase 14 1.61e-19 0.35
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.11e-16 0.35
SRC_RAT Src Proto-oncogene tyrosine-protein kinase Src 3.331e-16 0.30
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 8.882e-16 0.34
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 8.882e-16 0.34
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 8.882e-16 0.34
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 1.776e-15 0.34
MET_HUMAN MET Hepatocyte growth factor receptor 2.331e-15 0.40
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 4.219e-15 0.40
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 3.242e-14 0.34
ALBU_HUMAN ALB Serum albumin 4.141e-14 0.32
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 7.838e-14 0.34
P3C2A_HUMAN PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1.202e-13 0.56
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 1.242e-13 0.34
CTRO_HUMAN CIT Citron Rho-interacting kinase 7.285e-13 0.34
NLK_HUMAN NLK Serine/threonine-protein kinase NLK 7.285e-13 0.34
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 8.008e-13 0.34
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 2.068e-12 0.34
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 2.068e-12 0.34
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 3.364e-12 0.34
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 7.806e-12 0.36
CDKL3_HUMAN CDKL3 Cyclin-dependent kinase-like 3 1.456e-11 0.34
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 1.581e-11 0.40
HSPB1_HUMAN HSPB1 Heat shock protein beta-1 1.597e-11 0.31
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 2.387e-11 0.34
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 3.187e-11 0.34
EGFR_HUMAN EGFR Epidermal growth factor receptor 4.532e-11 0.40
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 4.858e-11 0.34
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 5.119e-11 0.34
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 9.305e-11 0.34
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 1.114e-10 0.34
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 1.285e-10 0.34
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 1.966e-10 0.34
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 3.52e-10 0.31
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 4.185e-10 0.34
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 4.192e-10 0.34
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 4.192e-10 0.34
MK15_HUMAN MAPK15 Mitogen-activated protein kinase 15 5.359e-10 0.34
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 5.557e-10 0.34
SC5A7_HUMAN SLC5A7 High affinity choline transporter 1 6.27e-10 0.35
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 7.348e-10 0.34
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 8.934e-10 0.34
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 8.95e-10 0.34
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 1.615e-09 0.34
PDE9A_RAT Pde9a High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 1.815e-09 0.31
AURKA_HUMAN AURKA Aurora kinase A 2.78e-09 0.41
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 3.513e-09 0.34
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 4.77e-09 0.34
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 4.988e-09 0.34
MYO3A_HUMAN MYO3A Myosin-IIIa 4.988e-09 0.34
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 7.804e-09 0.34
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 9.88e-09 0.36
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 1.334e-08 0.34
MYO3B_HUMAN MYO3B Myosin-IIIb 1.334e-08 0.34
RON_HUMAN MST1R Macrophage-stimulating protein receptor 2.177e-08 0.34
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 2.749e-08 0.33
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 2.89e-08 0.34
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 4.045e-08 0.31
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 4.225e-08 0.34
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 4.756e-08 0.34
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 6.858e-08 0.34
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 7.528e-08 0.34
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 7.864e-08 0.34
QPCT_HUMAN QPCT Glutaminyl-peptide cyclotransferase 9.871e-08 0.38
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 1.369e-07 0.34
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 1.369e-07 0.34
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 2.485e-07 0.34
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 2.536e-07 0.40
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 2.551e-07 0.34
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 2.554e-07 0.34
HRH3_RAT Hrh3 Histamine H3 receptor 2.87e-07 0.36
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 3.822e-07 0.40
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 4.501e-07 0.34
M3K10_HUMAN MAP3K10 Mitogen-activated protein kinase kinase kinase 10 4.931e-07 0.34
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 7.045e-07 0.29
INSRR_HUMAN INSRR Insulin receptor-related protein 7.551e-07 0.34
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 7.551e-07 0.34
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 7.551e-07 0.34
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 1.214e-06 0.34
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 1.214e-06 0.34
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 1.214e-06 0.34
ARAF_HUMAN ARAF Serine/threonine-protein kinase A-Raf 1.295e-06 0.34
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 1.612e-06 0.34
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 1.847e-06 0.34
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 1.88e-06 0.34
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 1.88e-06 0.34
TXK_HUMAN TXK Tyrosine-protein kinase TXK 1.884e-06 0.34
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 2.112e-06 0.39
KKCC2_HUMAN CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 2.229e-06 0.34
PDE6A_HUMAN PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 2.244e-06 0.29
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 2.818e-06 0.34
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 4.104e-06 0.34
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 4.104e-06 0.34
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 4.104e-06 0.34
PI42C_HUMAN PIP4K2C Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma 4.425e-06 0.34
DRD1_MOUSE Drd1 D(1A) dopamine receptor 5.429e-06 0.31
P3C2B_HUMAN PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 5.658e-06 0.56
HDAC2_HUMAN HDAC2 Histone deacetylase 2 5.785e-06 0.35
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 5.825e-06 0.34
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 5.825e-06 0.34
LCK_HUMAN LCK Tyrosine-protein kinase Lck 6.229e-06 0.40
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 6.436e-06 0.33
NK2R_MOUSE Tacr2 Substance-K receptor 6.733e-06 0.29
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 7.719e-06 0.34
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 7.877e-06 0.33
DMPK_HUMAN DMPK Myotonin-protein kinase 7.908e-06 0.34
MK10_RAT Mapk10 Mitogen-activated protein kinase 10 8.239e-06 0.30
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8.364e-06 0.29
KMO_HUMAN KMO Kynurenine 3-monooxygenase 8.68e-06 0.31

Lynestrenol

CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.1146 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.3536 1.00
Q690N0_BOVIN PGR Progesterone receptor 1.216e-54 0.70
SHBG_HUMAN SHBG Sex hormone-binding globulin 2.395e-54 0.67
STS_HUMAN STS Steryl-sulfatase 1.246e-28 0.37
F1Q298_CANLF NR3C1 Glucocorticoid receptor 1.529e-23 0.29
GCR_PIG NR3C1 Glucocorticoid receptor 1.529e-23 0.29
ANDR_RAT Ar Androgen receptor 4.128e-20 0.70
PRGR_RAT Pgr Progesterone receptor 1.708e-19 0.43
PRGR_RABIT PGR Progesterone receptor 2.22e-16 0.43
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 4.716e-10 0.31
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.319e-08 0.36
ESR1_HUMAN ESR1 Estrogen receptor 1.561e-08 0.70
NK1R_RAT Tacr1 Substance-P receptor 1.692e-07 0.35
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.312e-06 0.51

Piritramide

NPSR1_RAT Npsr1 Neuropeptide S receptor 5.351e-37 0.29
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 3.676e-31 0.53
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 1.908e-25 0.31
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 2.687e-24 0.62
NPSR1_HUMAN NPSR1 Neuropeptide S receptor 2.276e-22 0.33
MEN1_HUMAN MEN1 Menin 1.11e-16 0.31
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 1.665e-15 0.31
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 1.887e-15 0.58
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 2.998e-15 0.31
CALM_BOVIN CALM Calmodulin 7.857e-13 0.35
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 4.59e-12 0.62
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.406e-09 0.38
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.2e-08 0.31
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.48e-08 0.35
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 3.613e-07 0.38
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 2.813e-06 0.37

Favipiravir

TYRO_MOUSE Tyr Tyrosinase 9.7e-12 0.29
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 8.892e-09 0.29