Results of Job: search_a77754a3-656a-416a-ba39-06d7cf508e85

Query Target Key Target Name Description P-Value MaxTC

compound_1

IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 1.091e-157 0.49
CCND2_HUMAN CCND2 G1/S-specific cyclin-D2 1.263e-146 0.44
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 8.141e-138 0.49
SMG1_HUMAN SMG1 Serine/threonine-protein kinase SMG1 7.867e-134 0.43
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 5.757e-129 0.49
CDK4_HUMAN CDK4 Cyclin-dependent kinase 4 4.687e-102 0.49
CDK6_HUMAN CDK6 Cyclin-dependent kinase 6 9.629e-88 0.43
CCND3_HUMAN CCND3 G1/S-specific cyclin-D3 1.202e-87 0.44
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 1.46e-71 0.35
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 4.25e-67 0.43
DKK1_HUMAN DKK1 Dickkopf-related protein 1 1.382e-65 0.39
CCNB1_HUMAN CCNB1 G2/mitotic-specific cyclin-B1 2.851e-61 0.49
KPCD1_HUMAN PRKD1 Serine/threonine-protein kinase D1 5.72e-53 0.36
CCNH_HUMAN CCNH Cyclin-H 1.078e-52 0.42
CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 1.684e-49 0.51
SYK_HUMAN KARS1 Lysine--tRNA ligase 1.053e-48 0.39
IKKA_HUMAN CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha 2.493e-47 0.46
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 5.906e-46 0.38
IKKB_HUMAN IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 7.518e-46 0.47
CCNA2_HUMAN CCNA2 Cyclin-A2 9.11e-46 0.49
BCR_HUMAN BCR Breakpoint cluster region protein 1.494e-42 0.41
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 1.132e-39 0.34
CDK7_HUMAN CDK7 Cyclin-dependent kinase 7 1.429e-39 0.51
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 3.259e-38 0.44
CDK1_HUMAN CDK1 Cyclin-dependent kinase 1 1.759e-34 0.49
CCNB2_HUMAN CCNB2 G2/mitotic-specific cyclin-B2 4.262e-33 0.39
CCNB3_HUMAN CCNB3 G2/mitotic-specific cyclin-B3 4.262e-33 0.39
ACVR1_HUMAN ACVR1 Activin receptor type-1 2.889e-32 0.49
CCNA1_HUMAN CCNA1 Cyclin-A1 3.049e-32 0.49
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 6.68e-30 0.45
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 2.838e-28 0.42
HIPK1_HUMAN HIPK1 Homeodomain-interacting protein kinase 1 1.91e-27 0.39
ACVR1_MOUSE Acvr1 Activin receptor type-1 5.245e-27 0.33
JUN_HUMAN JUN Transcription factor AP-1 1.91e-24 0.40
Q0GMK6_RABIT CDK4 Cyclin-dependent kinase 4 2.985e-23 0.33
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 4.16e-23 0.49
ZAP70_HUMAN ZAP70 Tyrosine-protein kinase ZAP-70 1.636e-22 0.49
CCNT1_HUMAN CCNT1 Cyclin-T1 2.192e-22 0.51
CDK9_HUMAN CDK9 Cyclin-dependent kinase 9 1.814e-20 0.51
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 5.312e-20 0.52
BMP4_MOUSE Bmp4 Bone morphogenetic protein 4 8.377e-20 0.32
KPCD2_HUMAN PRKD2 Serine/threonine-protein kinase D2 1.382e-19 0.38
MP2K1_MOUSE Map2k1 Dual specificity mitogen-activated protein kinase kinase 1 3.983e-19 0.30
NMT_ASPFU nmt1 Glycylpeptide N-tetradecanoyltransferase 8.085e-19 0.31
INSR_HUMAN INSR Insulin receptor 1.64e-18 0.38
BMP4_HUMAN BMP4 Bone morphogenetic protein 4 3.257e-18 0.34
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 2.588e-17 0.55
MAPK5_HUMAN MAPKAPK5 MAP kinase-activated protein kinase 5 3.749e-17 0.33
YES_HUMAN YES1 Tyrosine-protein kinase Yes 3.803e-17 0.39
ALK_HUMAN ALK ALK tyrosine kinase receptor 1.11e-16 0.49
CCNE1_HUMAN CCNE1 G1/S-specific cyclin-E1 1.11e-16 0.49
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 1.11e-16 0.42
WEE1_HUMAN WEE1 Wee1-like protein kinase 1.11e-16 0.49
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 2.22e-16 0.49
DYR1B_HUMAN DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1B 2.22e-16 0.49
BMR1B_HUMAN BMPR1B Bone morphogenetic protein receptor type-1B 6.661e-16 0.42
GSK3B_RAT Gsk3b Glycogen synthase kinase-3 beta 7.772e-16 0.29
BPTF_HUMAN BPTF Nucleosome-remodeling factor subunit BPTF 8.882e-16 0.30
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 8.882e-16 0.50
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 1.665e-15 0.49
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 2.554e-15 0.30
MK10_RAT Mapk10 Mitogen-activated protein kinase 10 3.775e-15 0.45
BMPR2_HUMAN BMPR2 Bone morphogenetic protein receptor type-2 1.765e-14 0.33
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 1.078e-13 0.39
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 1.262e-13 0.38
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 1.413e-13 0.49
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 2.206e-13 0.31
LCK_HUMAN LCK Tyrosine-protein kinase Lck 2.537e-13 0.47
CCR4_MOUSE Ccr4 C-C chemokine receptor type 4 4.223e-13 0.30
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 6.95e-13 0.49
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 8.29e-13 0.34
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.261e-12 0.49
KSYK_RAT Syk Tyrosine-protein kinase SYK 6.43e-12 0.32
MAPK2_HUMAN MAPKAPK2 MAP kinase-activated protein kinase 2 6.669e-12 0.35
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 7.544e-12 0.49
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 9.988e-12 0.37
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 1.054e-11 0.33
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 1.173e-11 0.37
PIM3_HUMAN PIM3 Serine/threonine-protein kinase pim-3 1.539e-11 0.40
ACV1B_HUMAN ACVR1B Activin receptor type-1B 2.507e-11 0.33
FAK1_HUMAN PTK2 Focal adhesion kinase 1 4.228e-11 0.49
KIT_MOUSE Kit Mast/stem cell growth factor receptor Kit 5.566e-11 0.32
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 1.248e-10 0.49
GALR2_HUMAN GALR2 Galanin receptor type 2 1.702e-10 0.30
AURKA_HUMAN AURKA Aurora kinase A 2.569e-10 0.49
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 4.242e-10 0.49
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 5.369e-10 0.49
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 6.826e-10 0.49
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 7.174e-10 0.49
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 1.601e-09 0.39
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 1.649e-09 0.35
PIM1_HUMAN PIM1 Serine/threonine-protein kinase pim-1 1.735e-09 0.40
TGFR1_HUMAN TGFBR1 TGF-beta receptor type-1 2.004e-09 0.42
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 2.129e-09 0.29
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 2.638e-09 0.49
EGFR_HUMAN EGFR Epidermal growth factor receptor 2.9e-09 0.47
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 3.176e-09 0.41
PAK3_HUMAN PAK3 Serine/threonine-protein kinase PAK 3 3.368e-09 0.31
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 3.547e-09 0.49
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 3.942e-09 0.35
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 4.078e-09 0.49
Q388H8_TRYB2 Glycylpeptide N-tetradecanoyltransferase 4.544e-09 0.32
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 5.648e-09 0.49
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 5.753e-09 0.49
O97467_PLAFA ht1 Hexose transporter 1 6.429e-09 0.33
NEK2_HUMAN NEK2 Serine/threonine-protein kinase Nek2 8.031e-09 0.49
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 9.803e-09 0.49
NMT1_HUMAN NMT1 Glycylpeptide N-tetradecanoyltransferase 1 1.71e-08 0.31
KPCA_HUMAN PRKCA Protein kinase C alpha type 1.797e-08 0.36
PAK2_HUMAN PAK2 Serine/threonine-protein kinase PAK 2 2.42e-08 0.31
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 2.651e-08 0.37
CD63_HUMAN CD63 CD63 antigen 3.249e-08 0.29
ACVL1_HUMAN ACVRL1 Serine/threonine-protein kinase receptor R3 3.761e-08 0.33
O61059_LEIME LmGT2 Glucose transporter 4.554e-08 0.33
RON_HUMAN MST1R Macrophage-stimulating protein receptor 5.159e-08 0.49
PDGFB_HUMAN PDGFB Platelet-derived growth factor subunit B 5.218e-08 0.43
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 5.781e-08 0.49
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 6.048e-08 0.49
DAPK3_HUMAN DAPK3 Death-associated protein kinase 3 6.136e-08 0.49
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 7.628e-08 0.38
CLK3_HUMAN CLK3 Dual specificity protein kinase CLK3 8.24e-08 0.31
AURKB_HUMAN AURKB Aurora kinase B 8.401e-08 0.49
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 8.488e-08 0.30
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 8.941e-08 0.49
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 1.016e-07 0.33
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 1.501e-07 0.33
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 1.93e-07 0.38
PAK4_HUMAN PAK4 Serine/threonine-protein kinase PAK 4 2.743e-07 0.49
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 2.754e-07 0.49
TYRO3_HUMAN TYRO3 Tyrosine-protein kinase receptor TYRO3 3.022e-07 0.49
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 3.914e-07 0.49
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 3.939e-07 0.42
CDK19_HUMAN CDK19 Cyclin-dependent kinase 19 4.981e-07 0.34
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 5.067e-07 0.38
PIM2_HUMAN PIM2 Serine/threonine-protein kinase pim-2 6.519e-07 0.37
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 7.661e-07 0.38
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 7.783e-07 0.33
CASP5_HUMAN CASP5 Caspase-5 7.813e-07 0.34
AAPK1_HUMAN PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 7.816e-07 0.49
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 8.215e-07 0.49
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 9.855e-07 0.38
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1.102e-06 0.49
KC1A_HUMAN CSNK1A1 Casein kinase I isoform alpha 1.635e-06 0.49
LUCI_AQULA Luciferin 4-monooxygenase 1.988e-06 0.32
PRKX_HUMAN PRKX cAMP-dependent protein kinase catalytic subunit PRKX 2.458e-06 0.49
CATK_RABIT CTSK Cathepsin K 2.641e-06 0.32
BRSK2_HUMAN BRSK2 Serine/threonine-protein kinase BRSK2 3.025e-06 0.30
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 3.279e-06 0.36
AVR2B_HUMAN ACVR2B Activin receptor type-2B 3.43e-06 0.28
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 3.449e-06 0.49
DPOL_VACCW POL DNA polymerase 4.151e-06 0.30
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 5.31e-06 0.28
MARK3_HUMAN MARK3 MAP/microtubule affinity-regulating kinase 3 5.779e-06 0.38
CASP4_HUMAN CASP4 Caspase-4 5.998e-06 0.34
PAK1_HUMAN PAK1 Serine/threonine-protein kinase PAK 1 6.522e-06 0.34
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 7.368e-06 0.38
E2AK2_HUMAN EIF2AK2 Interferon-induced, double-stranded RNA-activated protein kinase 7.701e-06 0.38
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 8.684e-06 0.28
MTOR_MOUSE Mtor Serine/threonine-protein kinase mTOR 9.924e-06 0.30