Results of Job: search_b4f3cea4-4ca6-452b-b51c-3dfc82b0cc1c

Query Target Key Target Name Description P-Value MaxTC

Darunavir

Q9YQ12_9HIV1 protease Protease 1.881e-272 1.00
O90781_9PLVG HIV-1 protease HIV-1 protease 7.6e-246 1.00
Q72874_9HIV1 pol Pol polyprotein 2.572e-176 1.00
POL_HV1A2 gag-pol Gag-Pol polyprotein 1.863e-201 0.62
Q9YQ30_9PLVG HIV-1 protease HIV-1 protease 6.777e-94 0.33
KLK5_HUMAN KLK5 Kallikrein-5 1.59e-42 0.32
MMP12_MOUSE Mmp12 Macrophage metalloelastase 2.309e-36 0.30
POL_HV1H2 gag-pol Gag-Pol polyprotein 5.472e-35 0.37
CATD_BOVIN CTSD Cathepsin D 3.83e-32 0.31
POL_HV1BR gag-pol Gag-Pol polyprotein 1.634e-23 0.86
P88142_9HIV2 pol Pol polyprotein 1.469e-20 0.33
RENI_HUMAN REN Renin 2.81e-19 0.35
CATL1_RAT Ctsl Cathepsin L1 4.042e-19 0.29
MMP2_MOUSE Mmp2 72 kDa type IV collagenase 1.664e-18 0.29
MMP9_MOUSE Mmp9 Matrix metalloproteinase-9 1.664e-18 0.29
RORG_HUMAN RORC Nuclear receptor ROR-gamma 2.22e-16 0.36
CPNS1_PIG CAPNS1 Calpain small subunit 1 1.443e-15 0.30
CATD_HUMAN CTSD Cathepsin D 1.577e-14 0.34
PEPA5_HUMAN PGA5 Pepsin A-5 5.718e-14 0.35
MMP3_HUMAN MMP3 Stromelysin-1 9.88e-12 0.39
KLK7_HUMAN KLK7 Kallikrein-7 3.487e-11 0.31
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 1.185e-10 0.30
PEPC_HUMAN PGC Gastricsin 2.359e-10 0.34
BACE2_HUMAN BACE2 Beta-secretase 2 5.83e-10 0.31
CHLE_HUMAN BCHE Cholinesterase 2.204e-09 0.36
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 2.927e-09 0.30
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 4.864e-09 0.28
CATE_HUMAN CTSE Cathepsin E 3.002e-08 0.34
APH1A_HUMAN APH1A Gamma-secretase subunit APH-1A 6.569e-08 0.35
APH1B_HUMAN APH1B Gamma-secretase subunit APH-1B 6.569e-08 0.35
NICA_HUMAN NCSTN Nicastrin 6.569e-08 0.35
PEN2_HUMAN PSENEN Gamma-secretase subunit PEN-2 6.619e-08 0.35
PSN2_HUMAN PSEN2 Presenilin-2 6.773e-08 0.35
BACE1_HUMAN BACE1 Beta-secretase 1 1.022e-07 0.32
PSN1_HUMAN PSEN1 Presenilin-1 1.374e-07 0.35
RORB_HUMAN RORB Nuclear receptor ROR-beta 1.509e-07 0.32
MMP8_HUMAN MMP8 Neutrophil collagenase 1.9e-06 0.34
RORA_HUMAN RORA Nuclear receptor ROR-alpha 2.191e-06 0.32
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 2.742e-06 0.34

Finasteride

S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 8.369e-231 1.00
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 6.391e-180 1.00
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6.403e-48 1.00
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 3.279e-44 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.7924 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.8689 1.00
GBRD_HUMAN GABRD Gamma-aminobutyric acid receptor subunit delta 8.344e-83 0.35
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 1.137e-70 0.42
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.932e-62 0.35
ANDR_RAT Ar Androgen receptor 7.531e-59 0.73
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.937e-33 0.34
GBRA4_HUMAN GABRA4 Gamma-aminobutyric acid receptor subunit alpha-4 2.424e-33 0.35
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 1.089e-32 0.37
SHBG_RAT Shbg Sex hormone-binding globulin 1.343e-26 0.33
SHBG_HUMAN SHBG Sex hormone-binding globulin 4.272e-24 0.36
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 4.185e-23 0.28
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.778e-21 0.34
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 4.103e-21 0.32
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 4.879e-18 0.29
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.11e-16 0.36
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.179e-13 0.29
GBRA1_HUMAN GABRA1 Gamma-aminobutyric acid receptor subunit alpha-1 1.542e-13 0.37
ANDR_MOUSE Ar Androgen receptor 2.577e-13 0.36
TAT_HV112 tat Protein Tat 1.926e-12 0.29
Q690N0_BOVIN PGR Progesterone receptor 1.078e-11 0.36
GBRG2_HUMAN GABRG2 Gamma-aminobutyric acid receptor subunit gamma-2 1.105e-11 0.37
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.683e-11 0.36
ERG2_YEAST ERG2 C-8 sterol isomerase 1.499e-08 0.36
GBRB3_HUMAN GABRB3 Gamma-aminobutyric acid receptor subunit beta-3 1.049e-07 0.35
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.124e-07 0.36
PRGR_RABIT PGR Progesterone receptor 2.222e-07 0.36
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 2.645e-07 0.28
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 3.2e-07 0.64
ANDR_HUMAN AR Androgen receptor 1.602e-06 0.40

Lapatinib

ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 5.136e-221 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 1.043e-196 1.00
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 2.606e-74 1.00
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 3.278e-37 1.00
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 9.603e-27 1.00
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 1.036e-22 1.00
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 4.197e-20 1.00
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 3.331e-16 1.00
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 3.775e-15 1.00
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 3.127e-13 1.00
P3C2B_HUMAN PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 3.375e-10 1.00
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 1.131e-08 1.00
AURKB_HUMAN AURKB Aurora kinase B 1.086e-06 1.00
PI4KB_HUMAN PI4KB Phosphatidylinositol 4-kinase beta 2.022e-05 1.00
MP2K7_HUMAN MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 4.084e-05 1.00
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 5.356e-05 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9516 1.00
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 9.03e-119 0.42
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 2.582e-101 0.42
ERBB2_RAT Erbb2 Receptor tyrosine-protein kinase erbB-2 2.533e-49 0.32
DUS2L_HUMAN DUS2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like 2.565e-40 0.32
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 6.593e-40 0.36
UBP10_HUMAN USP10 Ubiquitin carboxyl-terminal hydrolase 10 5.351e-37 0.29
UBP13_HUMAN USP13 Ubiquitin carboxyl-terminal hydrolase 13 5.351e-37 0.29
CD38_MOUSE Cd38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 1.405e-34 0.37
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 7.924e-31 0.42
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 1.574e-30 0.41
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 2.18e-30 0.37
EGFR_MOUSE Egfr Epidermal growth factor receptor 2.553e-26 0.30
LUCI_RENRE Coelenterazine h 2-monooxygenase 1.851e-23 0.53
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 1.627e-17 0.41
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 1.887e-15 0.41
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 4.885e-15 0.33
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 1.963e-13 0.33
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 5.898e-13 0.33
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 6.308e-11 0.40
INSR_HUMAN INSR Insulin receptor 1.595e-10 0.68
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 7.269e-10 0.68
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 8.091e-10 0.33
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 1.642e-09 0.33
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 1.442e-08 0.37
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 1.607e-08 0.28
CTRO_HUMAN CIT Citron Rho-interacting kinase 1.932e-08 0.33
CSK_HUMAN CSK Tyrosine-protein kinase CSK 3.322e-08 0.37
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 4.182e-08 0.41
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 5.158e-08 0.33
TIE2_HUMAN TEK Angiopoietin-1 receptor 1.847e-07 0.36
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 2.083e-07 0.36
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 2.61e-07 0.33
DYR1B_HUMAN DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1B 3.898e-07 0.40
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 5.529e-07 0.68
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 7.239e-07 0.37
HXK4_HUMAN GCK Hexokinase-4 8.999e-07 0.32
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 2.604e-06 0.33
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 3.234e-06 0.41
HDAC6_HUMAN HDAC6 Histone deacetylase 6 4.162e-06 0.68
TXK_HUMAN TXK Tyrosine-protein kinase TXK 4.999e-06 0.33
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 5.796e-06 0.30
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 5.901e-06 0.40
MKNK2_HUMAN MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 7.553e-06 0.33
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 8.258e-06 0.33

Oxymorphone

OPRK_CAVPO OPRK1 Kappa-type opioid receptor 3.777e-187 1.00
OPRM_MOUSE Oprm1 Mu-type opioid receptor 6.52e-185 1.00
OPRD_HUMAN OPRD1 Delta-type opioid receptor 7.257e-177 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.597e-147 1.00
OPRM_CAVPO OPRM1 Mu-type opioid receptor 2.022e-136 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.826e-131 1.00
OPRD_MOUSE Oprd1 Delta-type opioid receptor 4.762e-130 1.00
OPRD_RAT Oprd1 Delta-type opioid receptor 6.81e-125 1.00
OPRM_RAT Oprm1 Mu-type opioid receptor 4.747e-112 1.00
OPRK_RAT Oprk1 Kappa-type opioid receptor 8.455e-81 1.00
OPRM_BOVIN OPRM1 Mu-type opioid receptor 4.434e-132 0.66
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 4.9e-129 0.72
TLR4_MOUSE Tlr4 Toll-like receptor 4 2.048e-73 0.74
OPRX_CAVPO OPRL1 Nociceptin receptor 1.347e-69 0.51
OPRX_HUMAN OPRL1 Nociceptin receptor 1.11e-16 0.48
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 7.172e-14 0.35

Saquinavir

Q72874_9HIV1 pol Pol polyprotein 2.357e-181 1.00
P88142_9HIV2 pol Pol polyprotein 1.308e-90 1.00
Q9YQ12_9HIV1 protease Protease 6.118e-32 1.00
Q4U254_9ENTO protease Protease 2.395e-26 1.00
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 6.843e-21 1.00
O90781_9PLVG HIV-1 protease HIV-1 protease 4.677e-11 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.158e-07 1.00
OPRD_HUMAN OPRD1 Delta-type opioid receptor 2.295e-07 1.00
NK2R_HUMAN TACR2 Substance-K receptor 0.0003617 1.00
THAS_HUMAN TBXAS1 Thromboxane-A synthase 0.03421 1.00
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 0.03648 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.07136 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 0.1071 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.9895 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 0.9939 1.00
Q82134_9DELA prt Protease 6.961e-118 0.33
RENI_HUMAN REN Renin 1.023e-103 0.41
NPFF2_RAT Npffr2 Neuropeptide FF receptor 2 1.295e-69 0.32
RENI_RAT Ren1 Renin 8.833e-68 0.37
PEPC_HUMAN PGC Gastricsin 8.629e-66 0.31
PRO_HTL1A gag-pro Gag-Pro polyprotein 7.721e-58 0.31
OPRM_RAT Oprm1 Mu-type opioid receptor 3.48e-50 0.39
CATE_HUMAN CTSE Cathepsin E 4.753e-50 0.41
Q82323_9DELA Protease 1.224e-49 0.31
PRSS8_HUMAN PRSS8 Prostasin 9.526e-49 0.32
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 3.954e-46 0.34
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 1.936e-40 0.33
PEPA_PIG PGA Pepsin A 3.883e-40 0.41
SURA_ECOLI surA Chaperone SurA 9.548e-40 0.32
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 4.912e-39 0.32
OPRD_RAT Oprd1 Delta-type opioid receptor 1.83e-38 0.37
TRY1_BOVIN Cationic trypsin 3.325e-36 0.34
CATD_BOVIN CTSD Cathepsin D 2.247e-31 0.33
XPP2_RAT Xpnpep2 Xaa-Pro aminopeptidase 2 3.281e-31 0.30
NTR1_RAT Ntsr1 Neurotensin receptor type 1 5.571e-29 0.32
CATD_HUMAN CTSD Cathepsin D 2.645e-28 0.41
Q8I6Z5_PLAF7 Plasmepsin V 6.676e-28 0.31
XPP2_HUMAN XPNPEP2 Xaa-Pro aminopeptidase 2 1.374e-26 0.30
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 5.141e-26 0.32
XPP1_HUMAN XPNPEP1 Xaa-Pro aminopeptidase 1 6.549e-26 0.29
PLM1_PLAFA Plasmepsin-1 1.574e-24 0.32
CARP_YEAST PEP4 Saccharopepsin 2.518e-24 0.30
OPRD_MOUSE Oprd1 Delta-type opioid receptor 2.885e-23 0.34
NK1R_CAVPO TACR1 Substance-P receptor 3.398e-23 0.33
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 5.016e-22 0.34
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 9.707e-22 0.42
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.308e-21 0.34
TRY3_HUMAN PRSS3 Trypsin-3 1.75e-21 0.31
BRCA1_HUMAN BRCA1 Breast cancer type 1 susceptibility protein 4.031e-21 0.30
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 1.911e-20 0.34
MYLK_CHICK Mylk Myosin light chain kinase, smooth muscle 1.818e-19 0.30
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 6.202e-19 0.33
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 5.265e-18 0.31
PLM2_PLAFA Plasmepsin-2 3.107e-17 0.34
OPRK_RAT Oprk1 Kappa-type opioid receptor 7.772e-16 0.33
Q9ERT1_MOUSE TRH-R2 Thyrotropin-releasing hormone receptor 2 7.772e-16 0.31
NK1R_RAT Tacr1 Substance-P receptor 1.665e-15 0.34
TRFR_MOUSE Trhr Thyrotropin-releasing hormone receptor 1.776e-15 0.31
ACE_HUMAN ACE Angiotensin-converting enzyme 4.108e-15 0.33
BKRB2_RABIT BDKRB2 B2 bradykinin receptor 5.329e-15 0.30
THRB_HUMAN F2 Prothrombin 5.995e-15 0.35
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 1.891e-13 0.35
CTRC_HUMAN CTRC Chymotrypsin-C 2.861e-13 0.32
CASP9_HUMAN CASP9 Caspase-9 5.418e-13 0.30
KLK5_HUMAN KLK5 Kallikrein-5 5.745e-13 0.34
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 2.945e-12 0.29
PEPD_HUMAN PEPD Xaa-Pro dipeptidase 3.581e-12 0.30
B3DH72_DANRE oprd1b Opioid receptor, delta 1b 4.418e-12 0.29
O57585_DANRE oprd1a Opioid receptor homologue 4.418e-12 0.29
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 5.174e-12 0.33
ACE_RAT Ace Angiotensin-converting enzyme 5.808e-12 0.32
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 1.268e-11 0.31
AMPL_HUMAN LAP3 Cytosol aminopeptidase 2.982e-11 0.30
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 5.427e-11 0.29
MC3R_HUMAN MC3R Melanocortin receptor 3 6.945e-11 0.31
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 8.312e-11 0.34
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 1.09e-10 0.31
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 1.778e-10 0.35
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 3.154e-10 0.32
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 3.547e-10 0.32
CASPA_HUMAN CASP10 Caspase-10 3.931e-10 0.29
CMA1_HUMAN CMA1 Chymase 4.248e-10 0.32
BACE1_HUMAN BACE1 Beta-secretase 1 4.252e-10 0.36
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 5.682e-10 0.37
BLA1_STEMA Metallo-beta-lactamase L1 type 3 7.419e-10 0.32
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 9.012e-10 0.35
GLNA_HUMAN GLUL Glutamine synthetase 1.452e-09 0.30
PEPT1_DERPT DERP1 Peptidase 1 1.691e-09 0.30
ECE1_RAT Ece1 Endothelin-converting enzyme 1 4.078e-09 0.30
Q95PM0_TRYBR rhodesain Cysteine protease 6.581e-09 0.29
BACE2_HUMAN BACE2 Beta-secretase 2 7.481e-09 0.32
PAR1_HUMAN F2R Proteinase-activated receptor 1 7.7e-09 0.35
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 8.123e-09 0.33
FA10_BOVIN F10 Coagulation factor X 2.734e-08 0.32
O07911_STAAU agrC AgrC 4.33e-08 0.28
NK2R_RAT Tacr2 Substance-K receptor 4.721e-08 0.30
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 4.903e-08 0.41
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 6.601e-08 0.41
CATB_HUMAN CTSB Cathepsin B 8.863e-08 0.34
MC4R_RAT Mc4r Melanocortin receptor 4 1.365e-07 0.28
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 1.607e-07 0.32
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 1.91e-07 0.31
CTRA_BOVIN Chymotrypsinogen A 4.327e-07 0.30
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 4.897e-07 0.29
ACE_RABIT ACE Angiotensin-converting enzyme 5.417e-07 0.34
OPRM_MOUSE Oprm1 Mu-type opioid receptor 1.165e-06 0.33
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 1.231e-06 0.29
NTR2_HUMAN NTSR2 Neurotensin receptor type 2 1.358e-06 0.29
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 2.369e-06 0.30
LGMN_HUMAN LGMN Legumain 2.955e-06 0.30
Q690N0_BOVIN PGR Progesterone receptor 3.146e-06 0.49
APH1A_HUMAN APH1A Gamma-secretase subunit APH-1A 5.471e-06 0.34
APH1B_HUMAN APH1B Gamma-secretase subunit APH-1B 5.471e-06 0.34
NICA_HUMAN NCSTN Nicastrin 5.471e-06 0.34
PEN2_HUMAN PSENEN Gamma-secretase subunit PEN-2 5.503e-06 0.34
PSN2_HUMAN PSEN2 Presenilin-2 5.603e-06 0.34
CAN1_RAT Capn1 Calpain-1 catalytic subunit 5.954e-06 0.29
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 5.98e-06 0.29
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 9.65e-06 0.30
PSN1_HUMAN PSEN1 Presenilin-1 9.734e-06 0.34

Sitagliptin

DPP4_HUMAN DPP4 Dipeptidyl peptidase 4 1.334e-167 1.00
DPP4_MOUSE Dpp4 Dipeptidyl peptidase 4 7.259e-86 1.00
SEPR_HUMAN FAP Prolyl endopeptidase FAP 2.18e-40 1.00
DPP4_RAT Dpp4 Dipeptidyl peptidase 4 2.159e-21 1.00
DPP9_HUMAN DPP9 Dipeptidyl peptidase 9 2.494e-86 0.52
DPP8_HUMAN DPP8 Dipeptidyl peptidase 8 2.46e-79 0.66
DPP2_HUMAN DPP7 Dipeptidyl peptidase 2 6.979e-52 0.58
ACE_MOUSE Ace Angiotensin-converting enzyme 1.589e-28 0.33
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 7.337e-13 0.36
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 9.7e-12 0.29
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 9.7e-12 0.29
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 1.105e-10 0.29
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 7.304e-10 0.30
DPP4_PIG DPP4 Dipeptidyl peptidase 4 1.271e-09 0.49
LIPE_MOUSE Lipg Endothelial lipase 9.478e-09 0.31

Aripiprazole

DRD2_HUMAN DRD2 D(2) dopamine receptor 7.252e-144 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 3.748e-119 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 7.798e-104 1.00
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 6.808e-97 1.00
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 6.086e-93 1.00
DRD4_HUMAN DRD4 D(4) dopamine receptor 8.357e-90 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 7.784e-82 1.00
DRD2_RAT Drd2 D(2) dopamine receptor 1.825e-77 1.00
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 2.028e-75 1.00
H10_HUMAN H1-0 Histone H1.0 6.346e-68 1.00
DRD3_RAT Drd3 D(3) dopamine receptor 8.787e-62 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 9.944e-54 1.00
DRD5_HUMAN DRD5 D(1B) dopamine receptor 9.571e-47 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 2.674e-42 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.822e-38 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 3.202e-36 1.00
DRD4_RAT Drd4 D(4) dopamine receptor 4.974e-36 1.00
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.445e-30 1.00
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 3.211e-27 1.00
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.606e-23 1.00
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 6.944e-21 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 5.407e-20 1.00
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 7.29e-19 1.00
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 1.677e-17 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 7.772e-16 1.00
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 5.178e-13 1.00
DRD1_RAT Drd1 D(1A) dopamine receptor 1.002e-11 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 3.128e-09 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 4.697e-09 1.00
HRH1_CAVPO HRH1 Histamine H1 receptor 4.013e-08 1.00
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 3.207e-07 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 5.483e-07 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.432e-05 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.0007413 1.00
DRD1_PIG DRD1 D(1A) dopamine receptor 3.088e-88 0.46
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 3.395e-79 0.36
HRH3_HUMAN HRH3 Histamine H3 receptor 2.254e-61 0.44
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 3.844e-59 0.38
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 1.418e-53 0.36
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 5.462e-49 0.33
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 1.622e-45 0.35
CHLE_HORSE BCHE Cholinesterase 8.315e-38 0.68
ACES_ELEEL ache Acetylcholinesterase 4.278e-36 0.68
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 1.345e-34 0.33
HRH3_RAT Hrh3 Histamine H3 receptor 3.386e-34 0.38
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.842e-32 0.41
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 1.03e-26 0.43
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 9.065e-26 0.71
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 1.753e-25 0.33
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 1.72e-23 0.68
HRH3_CAVPO HRH3 Histamine H3 receptor 4.856e-23 0.35
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.916e-20 0.41
V1AR_RAT Avpr1a Vasopressin V1a receptor 3.737e-20 0.32
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 4.644e-20 0.68
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 5.395e-20 0.33
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 5.679e-20 0.46
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 1.452e-18 0.41
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 4.823e-18 0.32
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 3.888e-17 0.36
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 4.441e-16 0.40
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 6.661e-16 0.43
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 2.331e-15 0.36
ADA1B_MOUSE Adra1b Alpha-1B adrenergic receptor 2.442e-15 0.29
5HT1B_GORGO HTR1B 5-hydroxytryptamine receptor 1B 4.441e-15 0.29
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 1.21e-14 0.31
NORA_STAAU norA Quinolone resistance protein NorA 1.61e-14 0.30
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 2.964e-14 0.35
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 1.25e-13 0.35
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 2.188e-13 0.33
ACES_RAT Ache Acetylcholinesterase 1.597e-12 0.68
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 9.091e-12 0.32
OGT1_HUMAN OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 1.432e-11 0.30
DRD2_BOVIN DRD2 D(2) dopamine receptor 1.573e-11 0.32
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 2.621e-11 0.35
HRH2_HUMAN HRH2 Histamine H2 receptor 2.697e-11 0.36
ACES_MOUSE Ache Acetylcholinesterase 5.041e-11 0.31
TLR9_HUMAN TLR9 Toll-like receptor 9 1.011e-10 0.31
HRH3_MOUSE Hrh3 Histamine H3 receptor 5.36e-10 0.31
PNMT_HUMAN PNMT Phenylethanolamine N-methyltransferase 7.5e-10 0.31
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 3.147e-09 0.35
ESR2_HUMAN ESR2 Estrogen receptor beta 4.891e-09 0.34
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 7.417e-09 0.29
B2LA1_MOUSE Bcl2a1 Bcl-2-related protein A1 1.492e-08 0.34
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 2.021e-08 0.31
ESR1_HUMAN ESR1 Estrogen receptor 4.171e-08 0.34
ACES_HUMAN ACHE Acetylcholinesterase 6.546e-08 0.37
THB_HUMAN THRB Thyroid hormone receptor beta 8.068e-08 0.34
KPYM_HUMAN PKM Pyruvate kinase PKM 1.05e-07 0.31
SCN9A_MOUSE Scn9a Sodium channel protein type 9 subunit alpha 2.015e-07 0.35
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.734e-07 0.31
FABI_BACSU fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 5.904e-07 0.28
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 1.424e-06 0.30
MET_HUMAN MET Hepatocyte growth factor receptor 1.538e-06 0.35
DRD1_MOUSE Drd1 D(1A) dopamine receptor 9.278e-06 0.30

Telbivudine

KITH_HUMAN TK1 Thymidine kinase, cytosolic 6.456e-143 1.00
A3RLP8_CHV1 UL23 Thymidine kinase 1.564e-136 1.00
KITH_HHV1S TK Thymidine kinase 9.361e-101 1.00
Q03732_HBV HBcAg Capsid protein 1.377e-17 1.00
KTHY_MYCTU tmk Thymidylate kinase 3.812e-138 0.74
TYSY_LACCA thyA Thymidylate synthase 1.375e-123 0.70
KITM_HUMAN TK2 Thymidine kinase 2, mitochondrial 4.512e-120 0.65
TYPH_RAT Tymp Thymidine phosphorylase 3.644e-117 0.51
THYX_MYCTU thyX Flavin-dependent thymidylate synthase 1.78e-115 0.53
CDD_HUMAN CDA Cytidine deaminase 5.324e-104 0.34
DNK_DROME dnk Deoxynucleoside kinase 1.043e-102 0.59
KITH_RAT Tk1 Thymidine kinase, cytosolic 1.979e-99 0.79
KITH_VZVD TK Thymidine kinase 6.017e-98 0.42
D3ZGQ2_RAT Tk2 Thymidine kinase 2 3.871e-83 0.67
KTHY_HUMAN DTYMK Thymidylate kinase 8.379e-75 0.45
TYSY_BOVIN TYMS Thymidylate synthase 3.442e-71 0.46
CDD_MOUSE Cda Cytidine deaminase 1.777e-69 0.35
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 1.862e-69 0.47
TYSY_MYCTU thyA Thymidylate synthase ThyA 4.557e-66 0.53
DPOD1_HUMAN POLD1 DNA polymerase delta catalytic subunit 1.447e-64 0.52
Q6L709_HHV2 TK Thymidine kinase 1.896e-61 0.53
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 7.654e-53 0.53
KITH_HHV1 TK Thymidine kinase 2.043e-39 0.60
NT5M_HUMAN NT5M 5'(3')-deoxyribonucleotidase, mitochondrial 4.536e-38 0.30
DPOLB_HUMAN POLB DNA polymerase beta 4.861e-37 0.61
GGTA1_BOVIN GGTA1 N-acetyllactosaminide alpha-1,3-galactosyltransferase 6.395e-36 0.28
Q8KHJ3_NEIME lgtC Alpha 1,4 galactosyltransferase 6.395e-36 0.28
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 1.992e-33 0.46
DPOL_HHV1K DNA polymerase catalytic subunit 6.67e-32 0.52
KITH_VZVO TK Thymidine kinase 9.257e-32 0.39
Q8II92_PLAF7 Deoxyuridine 5'-triphosphate nucleotidohydrolase 2.03e-30 0.40
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 4.714e-28 0.46
P2RY6_RAT P2ry6 P2Y purinoceptor 6 2.645e-27 0.33
TYSY_MOUSE Tyms Thymidylate synthase 1.554e-26 0.74
RNAS1_HUMAN RNASE1 Ribonuclease pancreatic 4.502e-26 0.32
RNAS2_HUMAN RNASE2 Non-secretory ribonuclease 4.502e-26 0.32
ADA_MOUSE Ada Adenosine deaminase 4.212e-24 0.30
TYPH_HUMAN TYMP Thymidine phosphorylase 1.512e-23 0.57
DPOL_HHV11 DNA polymerase catalytic subunit 4.622e-23 0.52
DPOL_VZVD DNA polymerase catalytic subunit 4.622e-23 0.52
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 8.715e-21 0.53
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 6.068e-20 0.79
PYRF_YEAST URA3 Orotidine 5'-phosphate decarboxylase 3.774e-17 0.33
ADA_BOVIN ADA Adenosine deaminase 1.11e-15 0.46
Q9WJQ2_9HIV1 reverse transcriptase Reverse transcriptase protein 1.554e-15 0.71
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 1.776e-15 0.46
Q9WKE8_9HIV1 reverse transcriptase Reverse transcriptase 4.108e-15 0.71
PYRF_METTH pyrF Orotidine 5'-phosphate decarboxylase 4.441e-15 0.37
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 5.44e-15 0.28
TYSY_HUMAN TYMS Thymidylate synthase 2.709e-14 0.56
ADCY5_RAT Adcy5 Adenylate cyclase type 5 1.277e-13 0.38
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 9.009e-13 0.64
CHLE_HUMAN BCHE Cholinesterase 4.089e-12 0.50
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 1.101e-11 0.33
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 3.772e-11 0.33
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 2.137e-10 0.32
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 5.399e-09 0.45
GPR17_HUMAN GPR17 Uracil nucleotide/cysteinyl leukotriene receptor 1.495e-08 0.33
OGT1_HUMAN OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 5.567e-06 0.28

Metoclopramide

5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 1.57e-138 1.00
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 4.302e-138 1.00
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 2.548e-119 1.00
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.949e-38 1.00
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 4.79e-32 1.00
DRD3_RAT Drd3 D(3) dopamine receptor 4.56e-23 1.00
DRD2_RAT Drd2 D(2) dopamine receptor 3.218e-17 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 5.402e-08 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 4.527e-07 1.00
PERM_HUMAN MPO Myeloperoxidase 1.263e-05 1.00
DRD2_BOVIN DRD2 D(2) dopamine receptor 3.577e-05 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 5.44e-05 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.0002868 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.0445 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.6447 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.7894 1.00
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 2.318e-47 0.41
DRD2_CANLF DRD2 D(2) dopamine receptor 6.694e-38 0.30
DRD1_BOVIN DRD1 D(1A) dopamine receptor 8.48e-27 0.47
PSBA_SPIOL psbA Photosystem II protein D1 7.446e-24 0.30
UHRF1_HUMAN UHRF1 E3 ubiquitin-protein ligase UHRF1 1.803e-22 0.36
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 4.775e-21 0.47
PRP4_HUMAN PRPF4 U4/U6 small nuclear ribonucleoprotein Prp4 9.803e-19 0.30
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 3.489e-18 0.47
DRD4_HUMAN DRD4 D(4) dopamine receptor 5.099e-17 0.55
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 6.661e-16 0.33
VATB1_HUMAN ATP6V1B1 V-type proton ATPase subunit B, kidney isoform 5.551e-15 0.33
VPP1_CHICK ATP6V0A1 V-type proton ATPase 116 kDa subunit a isoform 1 5.551e-15 0.33
SNRK_HUMAN SNRK SNF-related serine/threonine-protein kinase 1.242e-13 0.30
STK3_MOUSE Stk3 Serine/threonine-protein kinase 3 1.242e-13 0.30
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 2.325e-13 0.35
ABCBB_RAT Abcb11 Bile salt export pump 2.186e-12 0.30
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 3.497e-12 0.30
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 1.281e-11 0.49
Q25856_PLAFA PFG6PD Glucose-6-phosphate dehydrogenase 3.739e-11 0.31
TLR1_MOUSE Tlr1 Toll-like receptor 1 9.402e-11 0.29
TLR2_MOUSE Tlr2 Toll-like receptor 2 9.402e-11 0.29
PI3R5_HUMAN PIK3R5 Phosphoinositide 3-kinase regulatory subunit 5 9.695e-11 0.29
DPOL_HHV6U U38 DNA polymerase catalytic subunit 1.554e-10 0.38
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 4.084e-10 0.29
ABCC8_HUMAN ABCC8 ATP-binding cassette sub-family C member 8 4.968e-10 0.33
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 6.654e-10 0.40
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 1.019e-09 0.36
ACES_RAT Ache Acetylcholinesterase 1.082e-09 0.34
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 1.645e-09 0.30
STK38_HUMAN STK38 Serine/threonine-protein kinase 38 1.645e-09 0.30
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 4.361e-09 0.59
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 4.546e-09 0.30
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 5.697e-09 0.33
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 5.73e-09 0.32
DLK1_HUMAN DLK1 Protein delta homolog 1 6.365e-09 0.30
ST38L_HUMAN STK38L Serine/threonine-protein kinase 38-like 6.365e-09 0.30
CAH3_HUMAN CA3 Carbonic anhydrase 3 6.835e-09 0.37
TLK2_HUMAN TLK2 Serine/threonine-protein kinase tousled-like 2 2.006e-08 0.30
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 3.998e-08 0.30
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 5.39e-08 0.30
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 5.39e-08 0.30
MYO3A_HUMAN MYO3A Myosin-IIIa 5.39e-08 0.30
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 5.39e-08 0.30
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 5.39e-08 0.30
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 5.602e-08 0.32
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 6.635e-08 0.74
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 6.95e-08 0.33
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 7.953e-08 0.29
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 1.276e-07 0.30
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 1.276e-07 0.30
MYO3B_HUMAN MYO3B Myosin-IIIb 1.276e-07 0.30
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.913e-07 0.58
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 2.729e-07 0.30
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 2.729e-07 0.30
SRPK2_HUMAN SRPK2 SRSF protein kinase 2 2.729e-07 0.30
STK11_HUMAN STK11 Serine/threonine-protein kinase STK11 2.729e-07 0.30
TLK1_HUMAN TLK1 Serine/threonine-protein kinase tousled-like 1 2.729e-07 0.30
PDIA1_HUMAN P4HB Protein disulfide-isomerase 3.327e-07 0.35
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 4.847e-07 0.31
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 5.365e-07 0.30
NIM1_HUMAN NIM1K Serine/threonine-protein kinase NIM1 5.365e-07 0.30
PRP4B_HUMAN PRPF4B Serine/threonine-protein kinase PRP4 homolog 5.365e-07 0.30
PRIO_SHEEP PRNP Major prion protein 9.034e-07 0.31
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 9.835e-07 0.30
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 9.835e-07 0.30
DHI1_RAT Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 1.114e-06 0.33
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 1.18e-06 0.35
ACES_HUMAN ACHE Acetylcholinesterase 1.502e-06 0.57
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 1.7e-06 0.30
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 1.7e-06 0.30
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 1.7e-06 0.30
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 1.7e-06 0.30
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 2.653e-06 0.30
BRSK2_HUMAN BRSK2 Serine/threonine-protein kinase BRSK2 2.794e-06 0.30
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 2.794e-06 0.30
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 2.794e-06 0.30
C3SLB7_ECOLX glmU Bifunctional protein GlmU 3.77e-06 0.29
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 4.4e-06 0.30
INSRR_HUMAN INSRR Insulin receptor-related protein 4.4e-06 0.30
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 4.4e-06 0.30
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 4.4e-06 0.30
MYLK4_HUMAN MYLK4 Myosin light chain kinase family member 4 4.4e-06 0.30
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 4.416e-06 0.40
THAS_RAT Tbxas1 Thromboxane-A synthase 4.704e-06 0.33
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 5.303e-06 0.30
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 6.12e-06 0.28
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 6.674e-06 0.30
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 6.674e-06 0.30
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 6.674e-06 0.30
MP2K6_HUMAN MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 6.674e-06 0.30
PI42B_HUMAN PIP4K2B Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 6.674e-06 0.30
VDR_HUMAN VDR Vitamin D3 receptor 7.169e-06 0.32
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 7.727e-06 0.36
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 7.894e-06 0.35
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 9.798e-06 0.30
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 9.798e-06 0.30

Naloxone

OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.096e-137 1.00
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 3.012e-173 0.75
OPRM_MOUSE Oprm1 Mu-type opioid receptor 2.812e-165 0.75
OPRD_HUMAN OPRD1 Delta-type opioid receptor 1.731e-161 0.79
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 2.489e-139 0.75
OPRM_CAVPO OPRM1 Mu-type opioid receptor 2.866e-120 0.75
OPRD_RAT Oprd1 Delta-type opioid receptor 5.12e-119 0.75
OPRD_MOUSE Oprd1 Delta-type opioid receptor 7.306e-119 0.75
OPRM_HUMAN OPRM1 Mu-type opioid receptor 3.438e-116 0.79
OPRM_BOVIN OPRM1 Mu-type opioid receptor 7.383e-114 0.53
OPRM_RAT Oprm1 Mu-type opioid receptor 4.523e-106 0.75
TLR4_MOUSE Tlr4 Toll-like receptor 4 6.312e-72 0.71
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.715e-70 0.75
OPRX_CAVPO OPRL1 Nociceptin receptor 3.238e-25 0.67
OPRX_HUMAN OPRL1 Nociceptin receptor 1.11e-16 0.51
F7HEV7_MACMU YTHDF2 G_PROTEIN_RECEP_F1_2 domain-containing protein 2.22e-15 0.34
H9FL65_MACMU OPRK1 Kappa-type opioid receptor 2.22e-15 0.34
OPRM_MACMU OPRM1 Mu-type opioid receptor 9.681e-14 0.34

Captopril

ACE_HUMAN ACE Angiotensin-converting enzyme 9.137e-135 1.00
ACE_RABIT ACE Angiotensin-converting enzyme 4.327e-131 1.00
ACE_RAT Ace Angiotensin-converting enzyme 2.78e-128 1.00
DAPE_HAEIN dapE Succinyl-diaminopimelate desuccinylase 2.714e-79 1.00
THRB_HUMAN F2 Prothrombin 7.353e-24 1.00
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 4.197e-20 1.00
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.311e-09 1.00
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 3.89e-05 1.00
RENI_HUMAN REN Renin 0.01077 1.00
XPP2_HUMAN XPNPEP2 Xaa-Pro aminopeptidase 2 2.02e-96 0.60
DEF_STRPN def Peptide deformylase 1.059e-91 0.34
DEF_STAAU def Peptide deformylase 6.081e-85 0.34
TRFR_MOUSE Trhr Thyrotropin-releasing hormone receptor 1.539e-81 0.32
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 1.111e-78 0.35
TPP2_RAT Tpp2 Tripeptidyl-peptidase 2 4.854e-74 0.47
MLX_HUMAN MLX Max-like protein X 2.006e-70 0.34
Q9ERT1_MOUSE TRH-R2 Thyrotropin-releasing hormone receptor 2 6.894e-69 0.31
IGA_NEIGO iga IgA-specific serine endopeptidase autotransporter 9.734e-64 0.46
XPP1_HUMAN XPNPEP1 Xaa-Pro aminopeptidase 1 1.302e-63 0.38
XPP2_RAT Xpnpep2 Xaa-Pro aminopeptidase 2 1.52e-62 0.38
LKHA4_CAVPO LTA4H Leukotriene A-4 hydrolase 2.054e-60 0.42
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 4.884e-58 0.37
PEPD_HUMAN PEPD Xaa-Pro dipeptidase 1.912e-54 0.37
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 2.153e-51 0.33
Q9R297_RAT Mlnr Motilin receptor 7.075e-48 0.31
PPCE_BOVIN PREP Prolyl endopeptidase 1.625e-47 0.44
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 3.177e-43 0.32
BRCA1_HUMAN BRCA1 Breast cancer type 1 susceptibility protein 3.287e-41 0.30
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 2.655e-40 0.31
TRFR_RAT Trhr Thyrotropin-releasing hormone receptor 2.7e-39 0.33
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 4.685e-39 0.48
NEP_RAT Mme Neprilysin 2.807e-38 0.72
BIRC7_HUMAN BIRC7 Baculoviral IAP repeat-containing protein 7 2.223e-37 0.30
PPCE_ELIME f1pep1 Prolyl endopeptidase 1.609e-35 0.28
TRFR_HUMAN TRHR Thyrotropin-releasing hormone receptor 3.029e-34 0.31
MVD1_HUMAN MVD Diphosphomevalonate decarboxylase 9.77e-32 0.40
CBPA1_BOVIN CPA1 Carboxypeptidase A1 1.881e-29 0.37
PPCE_PIG PREP Prolyl endopeptidase 4.295e-29 0.35
ELNE_HUMAN ELANE Neutrophil elastase 5.568e-28 0.38
TR10A_HUMAN TNFRSF10A Tumor necrosis factor receptor superfamily member 10A 1.288e-26 0.33
ESTD_PIG ESD S-formylglutathione hydrolase 2.847e-23 0.29
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 8.657e-23 0.51
NEP_RABIT MME Neprilysin 1.047e-22 0.52
CBPB1_PIG CPB1 Carboxypeptidase B 2.118e-22 0.35
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 2.701e-21 0.35
CTRA_BOVIN Chymotrypsinogen A 7.424e-21 0.35
PPCE_MOUSE Prep Prolyl endopeptidase 1.432e-20 0.29
OPRM_RAT Oprm1 Mu-type opioid receptor 2.301e-20 0.38
PPCE_RAT Prep Prolyl endopeptidase 2.876e-20 0.35
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 4.879e-18 0.29
AMPL_HUMAN LAP3 Cytosol aminopeptidase 2.258e-17 0.38
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 4.544e-17 0.32
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 7.772e-16 0.31
OPRD_RAT Oprd1 Delta-type opioid receptor 7.55e-15 0.38
LGMN_MOUSE Lgmn Legumain 1.678e-13 0.29
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 4.167e-13 0.38
CATG_HUMAN CTSG Cathepsin G 8.999e-13 0.32
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.123e-12 0.32
OPRM_CAVPO OPRM1 Mu-type opioid receptor 4.699e-12 0.31
ACE_MOUSE Ace Angiotensin-converting enzyme 5.809e-12 0.51
GRAB_HUMAN GZMB Granzyme B 1.041e-11 0.34
GYS1_HUMAN GYS1 Glycogen [starch] synthase, muscle 1.09e-11 0.30
NRP1_RAT Nrp1 Neuropilin-1 1.15e-11 0.28
CMA1_HUMAN CMA1 Chymase 1.258e-11 0.37
A3EZI9_9HEPC NS3 Genome polyprotein 6.852e-11 0.41
TRY1_BOVIN Cationic trypsin 7.185e-11 0.32
NTR2_HUMAN NTSR2 Neurotensin receptor type 2 8.161e-11 0.30
F1SH20_PIG TRHDE Uncharacterized protein 1.105e-10 0.29
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 1.071e-09 0.35
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.117e-09 0.30
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 1.871e-09 0.34
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 2.301e-09 0.29
OPRK_RAT Oprk1 Kappa-type opioid receptor 2.518e-09 0.31
AMPN_HUMAN ANPEP Aminopeptidase N 2.683e-09 0.40
NK1R_RAT Tacr1 Substance-P receptor 4.004e-09 0.37
PPCE_HUMAN PREP Prolyl endopeptidase 1.992e-08 0.31
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 2.378e-08 0.30
TRY1_HUMAN PRSS1 Trypsin-1 3.684e-08 0.42
Q95PM0_TRYBR rhodesain Cysteine protease 6.313e-08 0.34
CASP2_HUMAN CASP2 Caspase-2 6.881e-08 0.31
Q9V396_DROME CAH1 Carbonic anhydrase 1 7.174e-08 0.51
Q9VTU8_DROME CAH2 Carbonic anhydrase 2, isoform A 7.174e-08 0.51
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 2.041e-07 0.29
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 4.802e-07 0.29
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 8.474e-07 0.34
DPP4_HUMAN DPP4 Dipeptidyl peptidase 4 1.252e-06 0.40
NEP_HUMAN MME Neprilysin 1.482e-06 0.52
DPP8_HUMAN DPP8 Dipeptidyl peptidase 8 1.567e-06 0.32
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 4.842e-06 0.30
CBPB2_HUMAN CPB2 Carboxypeptidase B2 7.741e-06 0.35
CTRC_HUMAN CTRC Chymotrypsin-C 7.864e-06 0.34
CATH_HUMAN CTSH Pro-cathepsin H 8.198e-06 0.30

Docetaxel

GHRHR_HUMAN GHRHR Growth hormone-releasing hormone receptor 2.9e-124 1.00
NK2R_HUMAN TACR2 Substance-K receptor 0.008848 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.9947 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 1 1.00
TBB3_HUMAN TUBB3 Tubulin beta-3 chain 3.563e-30 0.77
Q25270_LEIDO beta-tubulin Beta-tubulin 1.332e-15 0.77
UB2D3_HUMAN UBE2D3 Ubiquitin-conjugating enzyme E2 D3 8.704e-14 0.30
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 9.384e-09 0.77

Kanamycin

CXB2_HUMAN GJB2 Gap junction beta-2 protein 2.9e-124 1.00
FABH_ECOLI fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 8.911e-26 1.00
Q77YF8_HV1H2 rev Protein Rev 5.66e-89 0.77
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 2.436e-72 0.42
LEG4_HUMAN LGALS4 Galectin-4 3.213e-71 0.42
LEG8_HUMAN LGALS8 Galectin-8 3.213e-71 0.42
AMYP_HUMAN AMY2A Pancreatic alpha-amylase 5.182e-57 0.35
FGF1_HUMAN FGF1 Fibroblast growth factor 1 3.443e-40 0.40
GGTA1_PIG GGTA1 N-acetyllactosaminide alpha-1,3-galactosyltransferase 4.067e-39 0.31
B4EH87_BURCJ Lectin 9.979e-39 0.42
Q70E71_9ENTE aac(6')-Ii Aminoglycoside N(6')-acetyltransferase 8.338e-31 0.29
TYRO_HUMAN TYR Tyrosinase 1.691e-28 0.35
FGF2_HUMAN FGF2 Fibroblast growth factor 2 2.315e-25 0.40
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 6.982e-24 0.30
CHIT_YEAST CTS1 Endochitinase 9.719e-24 0.29
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 1.678e-18 0.40
LEG3_HUMAN LGALS3 Galectin-3 1.11e-16 0.42
GDE_RABIT AGL Glycogen debranching enzyme 4.441e-16 0.35
LEF_BACAN lef Lethal factor 6.661e-16 0.62
AMY1A_HUMAN AMY1A Alpha-amylase 1 9.992e-16 0.30
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.554e-15 0.88
TAT_HV112 tat Protein Tat 8.449e-14 0.33
P94451_GEOSE Alpha-amylase 1.102e-13 0.30
CD69_HUMAN CD69 Early activation antigen CD69 2.397e-12 0.30
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 8.544e-10 0.29
LEG9_HUMAN LGALS9 Galectin-9 9.151e-08 0.35
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 1.914e-07 0.29
CAH14_HUMAN CA14 Carbonic anhydrase 14 4.959e-07 0.36
CAH9_HUMAN CA9 Carbonic anhydrase 9 1.61e-06 0.45
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.267e-06 0.45
LYAG_RAT Gaa Lysosomal alpha-glucosidase 2.457e-06 0.35

Podofilox

VE2_HPV1 E2 Regulatory protein E2 2.9e-124 1.00
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 5.119e-34 1.00
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 3.853e-10 1.00
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 1.145e-06 1.00
PAX8_HUMAN PAX8 Paired box protein Pax-8 0.0003032 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.03137 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.05509 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.08166 1.00
GCR_HUMAN NR3C1 Glucocorticoid receptor 0.8069 1.00
EDNRB_MOUSE Ednrb Endothelin receptor type B 5.104e-54 0.33
EDNRA_MOUSE Ednra Endothelin-1 receptor 1.15e-33 0.33
Q9XSW7_PIG Phosphodiesterase 1.287e-20 0.33
T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 2.22e-16 0.31
EDNRA_HUMAN EDNRA Endothelin-1 receptor 7.772e-16 0.39
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 2.98e-13 0.51
EDNRB_HUMAN EDNRB Endothelin receptor type B 1.415e-12 0.33
HDAC3_HUMAN HDAC3 Histone deacetylase 3 8.219e-12 0.51
ITF2_HUMAN TCF4 Transcription factor 4 1.215e-11 0.31
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 1.383e-11 0.28
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 2.965e-10 0.30
TF_HUMAN F3 Tissue factor 1.165e-07 0.32
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.261e-07 0.51
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.942e-06 0.33

Posaconazole

CP51A_ASPFU cyp51A 14-alpha sterol demethylase Cyp51A 1.679e-111 1.00
Q96W81_ASPFM cyp51B 14-alpha sterol demethylase 1.607e-92 1.00
CP51_CANAL ERG11 Lanosterol 14-alpha demethylase 1.819e-78 1.00
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 6.454e-09 1.00
CP21A_HUMAN CYP21A2 Steroid 21-hydroxylase 9.702e-88 0.32
CP11A_RAT Cyp11a1 Cholesterol side-chain cleavage enzyme, mitochondrial 2.166e-59 0.32
CP7A1_RAT Cyp7a1 Cytochrome P450 7A1 2.166e-59 0.32
CP3A5_HUMAN CYP3A5 Cytochrome P450 3A5 6.678e-41 0.32
CP51A_RAT Cyp51a1 Lanosterol 14-alpha demethylase 2.445e-29 0.32
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 3.789e-24 0.55
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 3.389e-21 0.32
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 2.649e-10 0.32
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 4.231e-09 0.55
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.443e-08 0.55
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.338e-07 0.32
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 8.752e-07 0.32

Propafenone

MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.955e-111 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 2.736e-06 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.01757 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.2644 1.00
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 1.984e-124 0.46
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 1.034e-107 0.55
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 9.056e-104 0.46
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 8.314e-67 0.55
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 2.035e-64 0.42
GP174_HUMAN GPR174 Probable G-protein coupled receptor 174 9.592e-58 0.33
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 3.614e-51 0.37
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 1.149e-47 0.34
P2Y10_HUMAN P2RY10 Putative P2Y purinoceptor 10 2.689e-45 0.32
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 1.546e-41 0.31
CASR_BOVIN CASR Extracellular calcium-sensing receptor 2.281e-40 0.32
Q8ILP4_PLAF7 Pantothenate kinase, putative 2.83e-38 0.30
PDS_SYNE7 pds 15-cis-phytoene desaturase 2.701e-37 0.34
Q5YLN7_CANLF SCN5A Voltage-gated sodium channel Nav1.5 cardiac isoform 2.222e-36 0.29
GLT_PYRHO Glutamate transporter homolog 1.609e-35 0.28
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 2.002e-35 0.36
CASR_HUMAN CASR Extracellular calcium-sensing receptor 1.267e-30 0.42
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 2.686e-29 0.42
GPR34_HUMAN GPR34 Probable G-protein coupled receptor 34 3.875e-25 0.32
HMOX1_HUMAN HMOX1 Heme oxygenase 1 2.158e-24 0.30
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 2.246e-24 0.34
SCN9A_MOUSE Scn9a Sodium channel protein type 9 subunit alpha 8.47e-24 0.36
SCN1A_HUMAN SCN1A Sodium channel protein type 1 subunit alpha 1.085e-23 0.36
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 3.466e-21 0.31
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 1.887e-20 0.31
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 1.371e-19 0.38
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 2.806e-18 0.33
SYFA_HAEIN pheS Phenylalanine--tRNA ligase alpha subunit 4.879e-18 0.29
SYFA_STRPN pheS Phenylalanine--tRNA ligase alpha subunit 4.879e-18 0.29
SCYD_MAGO7 SDH1 Scytalone dehydratase 1.884e-17 0.32
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 1.11e-16 0.36
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 2.22e-16 0.30
HCN1_HUMAN HCN1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 6.661e-16 0.31
AMP1_PLAFQ M1 family aminopeptidase 7.772e-16 0.31
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 1.776e-15 0.38
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 2.665e-15 0.29
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 2.887e-15 0.38
HCN4_HUMAN HCN4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 5.773e-15 0.31
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 7.883e-15 0.28
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 1.174e-13 0.33
Q53I59_TRYCR PDEC Phosphodiesterase 1.188e-13 0.37
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 2.027e-13 0.39
ANDR_MOUSE Ar Androgen receptor 2.676e-13 0.34
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 3.922e-13 0.29
ADRB2_MOUSE Adrb2 Beta-2 adrenergic receptor 4.735e-13 0.32
AMPN_HUMAN ANPEP Aminopeptidase N 1.722e-12 0.37
EST1D_MOUSE Ces1d Carboxylesterase 1D 3.497e-12 0.30
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 4.628e-12 0.29
CMA1_HUMAN CMA1 Chymase 7.619e-12 0.33
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 8.819e-12 0.32
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 1.171e-11 0.38
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 2.944e-11 0.34
CASR_RAT Casr Extracellular calcium-sensing receptor 4.579e-11 0.37
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 6.797e-11 0.38
PTPRO_HUMAN PTPRO Receptor-type tyrosine-protein phosphatase O 1.257e-10 0.28
EST1_HUMAN CES1 Liver carboxylesterase 1 5.658e-10 0.30
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 5.934e-10 0.37
AMPN_PIG ANPEP Aminopeptidase N 1.665e-09 0.37
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 3.304e-09 0.31
HPPD_ARATH HPD 4-hydroxyphenylpyruvate dioxygenase 5.161e-09 0.28
CBPA1_BOVIN CPA1 Carboxypeptidase A1 2.708e-08 0.30
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 3.319e-08 0.32
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 3.646e-08 0.30
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 3.735e-08 0.39
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 4.016e-08 0.30
E3UJZ5_SPOLI Ecdysone receptor 4.145e-08 0.33
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 8.238e-08 0.30
RXFP1_HUMAN RXFP1 Relaxin receptor 1 8.869e-08 0.30
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 1.049e-07 0.32
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 1.427e-07 0.33
AMPL_HUMAN LAP3 Cytosol aminopeptidase 1.488e-07 0.29
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 1.688e-07 0.31
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 2.673e-07 0.30
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 3.913e-07 0.33
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 5.874e-07 0.31
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 1.042e-06 0.30
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 1.076e-06 0.36
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.107e-06 0.31
Q72874_9HIV1 pol Pol polyprotein 1.218e-06 0.31
GPR88_HUMAN GPR88 Probable G-protein coupled receptor 88 1.26e-06 0.35
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 1.41e-06 0.34
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 1.511e-06 0.34
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 1.787e-06 0.34
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 2.051e-06 0.29
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 2.942e-06 0.32
NR1H4_MOUSE Nr1h4 Bile acid receptor 3.073e-06 0.30
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 3.77e-06 0.29
ACE_HUMAN ACE Angiotensin-converting enzyme 3.937e-06 0.30
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 4.208e-06 0.33
PTGES_HUMAN PTGES Prostaglandin E synthase 6.124e-06 0.33
CTRA_BOVIN Chymotrypsinogen A 7.374e-06 0.33
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 7.574e-06 0.33
GRIA4_RAT Gria4 Glutamate receptor 4 8.194e-06 0.31
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 9.379e-06 0.36

Ceftriaxone

S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 9.817e-109 1.00
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 5.723e-67 1.00
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 4.092e-58 1.00
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 2.091e-07 1.00
OXDA_HUMAN DAO D-amino-acid oxidase 0.001779 1.00
PBPA_PSEAE mrcA Penicillin-binding protein 1A 2.162e-82 0.38
B2ZTR6_ACIBA Beta-lactamase 3.302e-66 0.71
D6NSM8_ACIBA ampC Beta-lactamase 3.302e-66 0.71
Q83TT7_ECOLX ampC AmpC 9.982e-57 0.38
Q7DHH4_STAAU mecA MecA 3.092e-44 0.35
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 1.388e-30 0.38
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 5.245e-27 0.33
Q3S5C3_SALNE sugE Efflux transporter 1.198e-23 0.38
Q48435_KLEPN bla LAT-2 Beta-lactamase 1.198e-23 0.38
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 6.026e-19 0.33
A2RP81_CITFR blaPER-2 Beta-lactamase 3.768e-17 0.38
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.11e-16 0.32
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 6.106e-15 0.70
AMPC_CITFR ampC Beta-lactamase 1.463e-13 0.33
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 3.475e-13 0.54
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 2.628e-09 0.31
STRP_STRP1 ska Streptokinase A 4.929e-07 0.57
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 8.07e-06 0.54

Dexamethasone

GCR_RAT Nr3c1 Glucocorticoid receptor 2.827e-103 1.00
Q690N0_BOVIN PGR Progesterone receptor 2.455e-66 1.00
GCR_HUMAN NR3C1 Glucocorticoid receptor 1.918e-52 1.00
MCR_HUMAN NR3C2 Mineralocorticoid receptor 2.32e-06 1.00
PRGR_HUMAN PGR Progesterone receptor 9.879e-05 1.00
ANDR_HUMAN AR Androgen receptor 0.1817 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.4004 1.00
ATTY_RAT Tat Tyrosine aminotransferase 2.119e-177 0.68
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.118e-38 0.49
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.45e-21 0.51
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.79e-13 0.34
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.022e-13 0.43
GLNA_HUMAN GLUL Glutamine synthetase 2.022e-13 0.43
IL6_HUMAN IL6 Interleukin-6 1.074e-10 0.43
MMP1_HUMAN MMP1 Interstitial collagenase 1.564e-09 0.70

Itraconazole

CP51A_ASPFU cyp51A 14-alpha sterol demethylase Cyp51A 4.727e-94 1.00
Q96W81_ASPFM cyp51B 14-alpha sterol demethylase 4.619e-78 1.00
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 2.958e-42 1.00
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 9.992e-16 1.00
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 8.327e-15 1.00
Q8IL32_PLAF7 Heat shock protein 90, putative 3.949e-06 1.00
CXCR1_HUMAN CXCR1 C-X-C chemokine receptor type 1 0.001074 1.00
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 0.002312 1.00
CYSP_TRYCR Cruzipain 0.005709 1.00
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 0.008029 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 0.01089 1.00
V2R_HUMAN AVPR2 Vasopressin V2 receptor 0.0297 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.05954 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.6094 1.00
CP21A_HUMAN CYP21A2 Steroid 21-hydroxylase 3.53e-163 0.58
CP11A_RAT Cyp11a1 Cholesterol side-chain cleavage enzyme, mitochondrial 8.886e-102 0.56
CP7A1_RAT Cyp7a1 Cytochrome P450 7A1 8.886e-102 0.56
CP3A5_HUMAN CYP3A5 Cytochrome P450 3A5 7.146e-70 0.56
CP51A_RAT Cyp51a1 Lanosterol 14-alpha demethylase 5.203e-50 0.56
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 5.32e-36 0.56
CP51_CANAL ERG11 Lanosterol 14-alpha demethylase 7e-34 0.55
HMOX1_RAT Hmox1 Heme oxygenase 1 4.077e-25 0.33
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 3.407e-17 0.56
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 3.253e-14 0.58
HMOX2_RAT Hmox2 Heme oxygenase 2 2.596e-12 0.31
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 3.645e-11 0.56
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 1.447e-10 0.58
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 3.711e-08 0.56
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 6.391e-07 0.75

Idarubicin

S10A4_HUMAN S100A4 Protein S100-A4 8.398e-90 1.00
PAX8_HUMAN PAX8 Paired box protein Pax-8 4.496e-06 1.00
STRP_STRP1 ska Streptokinase A 0.5042 1.00
FANCF_HUMAN FANCF Fanconi anemia group F protein 2.373e-55 0.44
CHIO_HUMAN CHN2 Beta-chimaerin 3.387e-51 0.41
1433G_HUMAN YWHAG 14-3-3 protein gamma 1.25e-40 0.83
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 2.599e-40 0.72
O40947_HHV8 ORF 73 4.576e-25 0.83
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 2.841e-18 0.72
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2.012e-13 0.72
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 1.331e-07 0.83
TLK1_HUMAN TLK1 Serine/threonine-protein kinase tousled-like 1 3.205e-07 0.29
CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 1.008e-06 0.72
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 7.581e-06 0.29

Ofloxacin

Q47245_ECOLX gyrA DNA gyrase subunit A 2.726e-89 1.00
C3SLN2_ECOLX gyrB DNA gyrase subunit B 2.83e-77 1.00
STE24_YEAST STE24 CAAX prenyl protease 1 2.428e-08 1.00
STRP_STRP1 ska Streptokinase A 2.689e-06 1.00
TRYP_PIG Trypsin 5.684e-05 1.00
ACEA_MYCTU icl Isocitrate lyase 7.603e-72 0.40
VATB2_HUMAN ATP6V1B2 V-type proton ATPase subunit B, brain isoform 1.89e-41 0.33
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 2.678e-22 0.84
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 2.996e-22 0.49
DPO3_BACSU polC DNA polymerase III PolC-type 3.278e-20 0.37
DPO1_THEAQ polA DNA polymerase I, thermostable 4.644e-17 0.34
PARC_STAAU parC DNA topoisomerase 4 subunit A 1.11e-16 0.45
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 2.665e-15 0.84
CNR2_RAT Cnr2 Cannabinoid receptor 2 3.388e-11 0.41
GYRA_MYCTU gyrA DNA gyrase subunit A 1.423e-08 0.45
GYRA_STAAU gyrA DNA gyrase subunit A 2.363e-07 0.42
WDR5_HUMAN WDR5 WD repeat-containing protein 5 6.609e-07 0.29
GYRA_ECOLI gyrA DNA gyrase subunit A 2.625e-06 0.42

Dasatinib

MYT1_HUMAN MYT1 Myelin transcription factor 1 2.714e-79 1.00
LCK_HUMAN LCK Tyrosine-protein kinase Lck 1.164e-64 1.00
BLK_MOUSE Blk Tyrosine-protein kinase Blk 1.089e-50 1.00
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 6.524e-44 1.00
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 4.353e-34 1.00
NEK11_HUMAN NEK11 Serine/threonine-protein kinase Nek11 1.735e-32 1.00
AVR2A_HUMAN ACVR2A Activin receptor type-2A 3.59e-28 1.00
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 3.59e-28 1.00
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 2.003e-25 1.00
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 4.419e-25 1.00
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 3.552e-24 1.00
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 7.773e-24 1.00
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 7.773e-24 1.00
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 2.128e-23 1.00
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 4.339e-23 1.00
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 9.712e-23 1.00
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 1.106e-22 1.00
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 4.632e-22 1.00
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 1.221e-21 1.00
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 2.089e-21 1.00
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 6.95e-21 1.00
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 7.789e-21 1.00
AVR2B_HUMAN ACVR2B Activin receptor type-2B 4.197e-20 1.00
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 4.197e-20 1.00
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 8.412e-20 1.00
TEC_HUMAN TEC Tyrosine-protein kinase Tec 1.962e-19 1.00
STK4_HUMAN STK4 Serine/threonine-protein kinase 4 6.842e-19 1.00
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 1.783e-18 1.00
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 4.409e-18 1.00
SIK1_HUMAN SIK1 Serine/threonine-protein kinase SIK1 1.039e-17 1.00
TAOK2_HUMAN TAOK2 Serine/threonine-protein kinase TAO2 1.039e-17 1.00
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 1.377e-17 1.00
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 4.449e-17 1.00
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 5.066e-17 1.00
M4K3_HUMAN MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 5.066e-17 1.00
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 1.11e-16 1.00
LCK_MOUSE Lck Proto-oncogene tyrosine-protein kinase LCK 1.11e-16 1.00
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1.11e-16 1.00
STK26_HUMAN STK26 Serine/threonine-protein kinase 26 1.11e-16 1.00
M4K1_HUMAN MAP4K1 Mitogen-activated protein kinase kinase kinase kinase 1 2.22e-16 1.00
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 2.22e-16 1.00
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 3.331e-16 1.00
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 4.441e-16 1.00
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 4.441e-16 1.00
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 7.772e-16 1.00
DMPK_HUMAN DMPK Myotonin-protein kinase 8.882e-16 1.00
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 8.882e-16 1.00
AURKA_HUMAN AURKA Aurora kinase A 1.221e-15 1.00
BMR1B_HUMAN BMPR1B Bone morphogenetic protein receptor type-1B 1.443e-15 1.00
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 1.443e-15 1.00
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 3.109e-15 1.00
YES_HUMAN YES1 Tyrosine-protein kinase Yes 1.044e-14 1.00
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 2.143e-14 1.00
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 2.387e-14 1.00
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 5.462e-14 1.00
M3K10_HUMAN MAP3K10 Mitogen-activated protein kinase kinase kinase 10 8.527e-14 1.00
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 9.259e-14 1.00
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 1.98e-13 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 3.05e-13 1.00
NLK_HUMAN NLK Serine/threonine-protein kinase NLK 5.523e-13 1.00
E2AK4_HUMAN EIF2AK4 eIF-2-alpha kinase GCN2 6.32e-13 1.00
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 1.048e-12 1.00
ACV1B_HUMAN ACVR1B Activin receptor type-1B 2.589e-12 1.00
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 6.428e-12 1.00
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 8.279e-12 1.00
TXK_HUMAN TXK Tyrosine-protein kinase TXK 8.627e-12 1.00
GAK_HUMAN GAK Cyclin-G-associated kinase 3.658e-11 1.00
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 1.651e-10 1.00
CSK_HUMAN CSK Tyrosine-protein kinase CSK 2.608e-10 1.00
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 3.864e-10 1.00
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 1.125e-09 1.00
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 2.031e-09 1.00
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 3.784e-09 1.00
HCK_HUMAN HCK Tyrosine-protein kinase HCK 5.891e-09 1.00
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 8.593e-09 1.00
ACVL1_HUMAN ACVRL1 Serine/threonine-protein kinase receptor R3 1.122e-08 1.00
SRMS_HUMAN SRMS Tyrosine-protein kinase Srms 2.037e-08 1.00
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 2.428e-08 1.00
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 3.408e-08 1.00
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 3.913e-08 1.00
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 4.201e-08 1.00
MK11_HUMAN MAPK11 Mitogen-activated protein kinase 11 7.18e-08 1.00
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 1.168e-07 1.00
FRK_HUMAN FRK Tyrosine-protein kinase FRK 3.979e-07 1.00
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 5.138e-07 1.00
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 7.652e-07 1.00
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1.331e-06 1.00
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 3.154e-06 1.00
BLK_HUMAN BLK Tyrosine-protein kinase Blk 4.73e-06 1.00
ACVR1_HUMAN ACVR1 Activin receptor type-1 4.785e-06 1.00
TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 6.282e-06 1.00
WEE1_HUMAN WEE1 Wee1-like protein kinase 9.474e-06 1.00
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 9.895e-06 1.00
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 1.214e-05 1.00
PTK6_HUMAN PTK6 Protein-tyrosine kinase 6 1.508e-05 1.00
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 1.811e-05 1.00
LIMK2_HUMAN LIMK2 LIM domain kinase 2 2.872e-05 1.00
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 5.59e-05 1.00
DYRK3_HUMAN DYRK3 Dual specificity tyrosine-phosphorylation-regulated kinase 3 7.282e-05 1.00
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 0.0001562 1.00
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 0.0001796 1.00
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 0.0002468 1.00
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 0.0002793 1.00
NEK2_HUMAN NEK2 Serine/threonine-protein kinase Nek2 0.0003095 1.00
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 0.0003324 1.00
PLK4_HUMAN PLK4 Serine/threonine-protein kinase PLK4 0.0003585 1.00
AURKB_HUMAN AURKB Aurora kinase B 0.0004657 1.00
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 0.000469 1.00
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 0.0004693 1.00
KC1A_HUMAN CSNK1A1 Casein kinase I isoform alpha 0.0004788 1.00
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 0.0006032 1.00
MRCKA_HUMAN CDC42BPA Serine/threonine-protein kinase MRCK alpha 0.000675 1.00
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 0.0006824 1.00
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 0.0008578 1.00
MINK1_HUMAN MINK1 Misshapen-like kinase 1 0.0008777 1.00
LIMK1_HUMAN LIMK1 LIM domain kinase 1 0.001473 1.00
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 0.001914 1.00
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 0.003168 1.00
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 0.00367 1.00
FGFR3_HUMAN FGFR3 Fibroblast growth factor receptor 3 0.005401 1.00
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 0.00564 1.00
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 0.006474 1.00
KC1E_HUMAN CSNK1E Casein kinase I isoform epsilon 0.006888 1.00
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 0.007022 1.00
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 0.007117 1.00
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 0.008209 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 0.009735 1.00
BTK_HUMAN BTK Tyrosine-protein kinase BTK 0.01185 1.00
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 0.01587 1.00
TGFR1_HUMAN TGFBR1 TGF-beta receptor type-1 0.02033 1.00
FGFR2_HUMAN FGFR2 Fibroblast growth factor receptor 2 0.03018 1.00
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 0.1289 1.00
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 0.1577 1.00
IRAK4_HUMAN IRAK4 Interleukin-1 receptor-associated kinase 4 0.3749 1.00
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 0.5252 1.00
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 3.878e-52 0.33
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 2.033e-34 0.38
G3I1B6_CRIGR 5-hydroxytryptamine receptor 1.859e-33 0.33
5HT1B_CRIGR HTR1B 5-hydroxytryptamine receptor 1B 4.679e-33 0.33
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.816e-29 0.38
AKIP_HUMAN AURKAIP1 Aurora kinase A-interacting protein 1.481e-24 0.30
DRD3_HUMAN DRD3 D(3) dopamine receptor 2.508e-24 0.36
ERMA_STAAN ermA1; ermA2; ermA3; ermA4; ermA5 rRNA adenine N-6-methyltransferase 3.736e-23 0.28
DRD1_PIG DRD1 D(1A) dopamine receptor 4.727e-23 0.36
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.276e-22 0.36
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 2.168e-20 0.38
STIM1_RAT Stim1 Stromal interaction molecule 1 3.991e-19 0.31
AUKBA_XENLA aurkb-a Aurora kinase B-A 5.051e-19 0.30
DRD4_HUMAN DRD4 D(4) dopamine receptor 7.644e-19 0.36
SHH_MOUSE Shh Sonic hedgehog protein 1.111e-18 0.33
DRD4_RAT Drd4 D(4) dopamine receptor 1.592e-17 0.36
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 4.255e-17 0.33
DRD3_RAT Drd3 D(3) dopamine receptor 1.11e-16 0.36
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 4.441e-16 0.36
SMO_HUMAN SMO Smoothened homolog 1.332e-15 0.34
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 4.774e-15 0.36
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 6.994e-14 0.35
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 8.415e-14 0.29
STIM1_HUMAN STIM1 Stromal interaction molecule 1 2.58e-13 0.30
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 3.424e-13 0.30
OGA_RAT Oga Protein O-GlcNAcase 4.607e-13 0.28
CASR_HUMAN CASR Extracellular calcium-sensing receptor 1.957e-12 0.35
CRCM1_RAT Orai1 Calcium release-activated calcium channel protein 1 3.266e-12 0.31
CRCM1_HUMAN ORAI1 Calcium release-activated calcium channel protein 1 4.092e-12 0.30
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 9.223e-12 0.34
ACOX1_RAT Acox1 Peroxisomal acyl-coenzyme A oxidase 1 2.675e-11 0.34
CDKL3_HUMAN CDKL3 Cyclin-dependent kinase-like 3 2.284e-10 0.30
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 5.144e-10 0.30
BTK_MOUSE Btk Tyrosine-protein kinase BTK 6.227e-10 0.30
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 9.185e-10 0.38
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 9.998e-10 0.30
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 2.693e-09 0.29
DLK1_HUMAN DLK1 Protein delta homolog 1 4.706e-09 0.30
ST38L_HUMAN STK38L Serine/threonine-protein kinase 38-like 4.706e-09 0.30
NPY5R_MOUSE Npy5r Neuropeptide Y receptor type 5 1.759e-08 0.34
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 2.048e-08 0.32
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 2.112e-08 0.35
DRD2_RAT Drd2 D(2) dopamine receptor 4.104e-08 0.36
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 4.123e-08 0.30
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 4.728e-08 0.33
DPOL_HHV6U U38 DNA polymerase catalytic subunit 5.301e-08 0.28
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 9.897e-08 0.30
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 2.077e-07 0.31
NEK5_HUMAN NEK5 Serine/threonine-protein kinase Nek5 2.142e-07 0.30
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 2.142e-07 0.30
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 2.142e-07 0.30
SRPK2_HUMAN SRPK2 SRSF protein kinase 2 2.142e-07 0.30
STK11_HUMAN STK11 Serine/threonine-protein kinase STK11 2.142e-07 0.30
TLK1_HUMAN TLK1 Serine/threonine-protein kinase tousled-like 1 2.142e-07 0.30
S27A1_MOUSE Slc27a1 Long-chain fatty acid transport protein 1 3.802e-07 0.28
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 4.256e-07 0.30
PRP4B_HUMAN PRPF4B Serine/threonine-protein kinase PRP4 homolog 4.256e-07 0.30
DRD2_MOUSE Drd2 D(2) dopamine receptor 4.781e-07 0.30
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 7.877e-07 0.30
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 1.365e-06 0.33
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 1.373e-06 0.30
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 1.373e-06 0.30
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 1.428e-06 0.28
O97467_PLAFA ht1 Hexose transporter 1 2.213e-06 0.32
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 2.275e-06 0.30
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 2.275e-06 0.30
O61059_LEIME LmGT2 Glucose transporter 2.453e-06 0.32
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.71e-06 0.32
TPOR_HUMAN MPL Thrombopoietin receptor 3.007e-06 0.29
INSRR_HUMAN INSRR Insulin receptor-related protein 3.608e-06 0.30
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 3.608e-06 0.30
MYLK4_HUMAN MYLK4 Myosin light chain kinase family member 4 3.608e-06 0.30
DRD1_HUMAN DRD1 D(1A) dopamine receptor 4.063e-06 0.36
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 4.437e-06 0.33
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 4.804e-06 0.32
DPOL_VACCW POL DNA polymerase 5.45e-06 0.29
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 5.508e-06 0.30
MP2K6_HUMAN MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 5.508e-06 0.30
PI42B_HUMAN PIP4K2B Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 5.508e-06 0.30
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 8.136e-06 0.30

Sunitinib

SNRK_HUMAN SNRK SNF-related serine/threonine-protein kinase 9.123e-70 1.00
PRP4_HUMAN PRPF4 U4/U6 small nuclear ribonucleoprotein Prp4 5.121e-61 1.00
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 1.353e-60 1.00
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 5.713e-52 1.00
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 9.731e-48 1.00
STK38_HUMAN STK38 Serine/threonine-protein kinase 38 9.731e-48 1.00
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 6.116e-46 1.00
ST38L_HUMAN STK38L Serine/threonine-protein kinase 38-like 1.317e-44 1.00
STK3_MOUSE Stk3 Serine/threonine-protein kinase 3 6.524e-44 1.00
SRPK2_HUMAN SRPK2 SRSF protein kinase 2 8.479e-44 1.00
STK11_HUMAN STK11 Serine/threonine-protein kinase STK11 8.479e-44 1.00
TLK2_HUMAN TLK2 Serine/threonine-protein kinase tousled-like 2 5.934e-42 1.00
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 6.786e-42 1.00
NIM1_HUMAN NIM1K Serine/threonine-protein kinase NIM1 6.786e-42 1.00
PRP4B_HUMAN PRPF4B Serine/threonine-protein kinase PRP4 homolog 6.786e-42 1.00
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 1.138e-39 1.00
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 1.138e-39 1.00
MYO3A_HUMAN MYO3A Myosin-IIIa 1.138e-39 1.00
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 1.138e-39 1.00
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1.138e-39 1.00
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 4.629e-39 1.00
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 1.185e-38 1.00
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 1.11e-37 1.00
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 5.514e-36 1.00
INSRR_HUMAN INSRR Insulin receptor-related protein 5.514e-36 1.00
BRSK2_HUMAN BRSK2 Serine/threonine-protein kinase BRSK2 6.053e-36 1.00
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 6.259e-36 1.00
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 6.259e-36 1.00
TLK1_HUMAN TLK1 Serine/threonine-protein kinase tousled-like 1 6.259e-36 1.00
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 8.096e-35 1.00
PI42B_HUMAN PIP4K2B Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 8.096e-35 1.00
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 9.608e-34 1.00
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 5.583e-33 1.00
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 5.583e-33 1.00
PAK5_HUMAN PAK5 Serine/threonine-protein kinase PAK 5 9.457e-33 1.00
PI51A_HUMAN PIP5K1A Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 9.457e-33 1.00
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 7.891e-32 1.00
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 1.01e-31 1.00
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 1.01e-31 1.00
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 1.01e-31 1.00
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 5.685e-31 1.00
RIOK1_HUMAN RIOK1 Serine/threonine-protein kinase RIO1 5.685e-31 1.00
RIOK3_HUMAN RIOK3 Serine/threonine-protein kinase RIO3 5.685e-31 1.00
YES_HUMAN YES1 Tyrosine-protein kinase Yes 6.568e-31 1.00
BMPR2_HUMAN BMPR2 Bone morphogenetic protein receptor type-2 3.592e-30 1.00
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 3.592e-30 1.00
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 1.535e-29 1.00
MYLK4_HUMAN MYLK4 Myosin light chain kinase family member 4 1.535e-29 1.00
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 2.017e-29 1.00
GRK4_HUMAN GRK4 G protein-coupled receptor kinase 4 2.017e-29 1.00
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 2.017e-29 1.00
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 1.019e-28 1.00
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 1.019e-28 1.00
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 1.019e-28 1.00
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 1.381e-28 1.00
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 1.381e-28 1.00
MP2K6_HUMAN MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 1.381e-28 1.00
DLK1_HUMAN DLK1 Protein delta homolog 1 3.59e-28 1.00
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 4.677e-28 1.00
ULK2_HUMAN ULK2 Serine/threonine-protein kinase ULK2 4.677e-28 1.00
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 1.967e-27 1.00
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 1.967e-27 1.00
PAK3_HUMAN PAK3 Serine/threonine-protein kinase PAK 3 1.967e-27 1.00
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 6.783e-27 1.00
MARK1_HUMAN MARK1 Serine/threonine-protein kinase MARK1 6.783e-27 1.00
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 6.783e-27 1.00
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 2.762e-26 1.00
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 2.762e-26 1.00
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 3.847e-26 1.00
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 3.847e-26 1.00
STK16_HUMAN STK16 Serine/threonine-protein kinase 16 9.336e-26 1.00
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 1.935e-25 1.00
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 1.935e-25 1.00
M4K3_HUMAN MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 2.969e-25 1.00
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 2.969e-25 1.00
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 3.482e-25 1.00
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 3.512e-25 1.00
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 4.527e-25 1.00
HIPK3_HUMAN HIPK3 Homeodomain-interacting protein kinase 3 8.926e-25 1.00
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 8.926e-25 1.00
STK26_HUMAN STK26 Serine/threonine-protein kinase 26 8.926e-25 1.00
M4K1_HUMAN MAP4K1 Mitogen-activated protein kinase kinase kinase kinase 1 2.547e-24 1.00
CDK16_HUMAN CDK16 Cyclin-dependent kinase 16 6.926e-24 1.00
MYO3B_HUMAN MYO3B Myosin-IIIb 7.773e-24 1.00
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 1.266e-23 1.00
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 4.695e-23 1.00
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 4.695e-23 1.00
STK4_HUMAN STK4 Serine/threonine-protein kinase 4 4.695e-23 1.00
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 4.695e-23 1.00
AURKC_HUMAN AURKC Aurora kinase C 7.799e-23 1.00
MP2K4_HUMAN MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 1.521e-22 1.00
HIPK1_HUMAN HIPK1 Homeodomain-interacting protein kinase 1 2.495e-22 1.00
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 2.495e-22 1.00
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 1.21e-21 1.00
DAPK2_HUMAN DAPK2 Death-associated protein kinase 2 1.321e-21 1.00
MYLK_CHICK Mylk Myosin light chain kinase, smooth muscle 1.321e-21 1.00
SIK1_HUMAN SIK1 Serine/threonine-protein kinase SIK1 1.321e-21 1.00
AAK1_HUMAN AAK1 AP2-associated protein kinase 1 2.545e-21 1.00
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 2.545e-21 1.00
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 9.228e-21 1.00
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 1.038e-20 1.00
CTRO_HUMAN CIT Citron Rho-interacting kinase 2.271e-20 1.00
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 2.888e-20 1.00
MARK4_HUMAN MARK4 MAP/microtubule affinity-regulating kinase 4 5.358e-20 1.00
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 7.122e-20 1.00
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 8.07e-20 1.00
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 1.215e-19 1.00
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 2.176e-19 1.00
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 2.176e-19 1.00
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 2.312e-19 1.00
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 2.656e-19 1.00
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 2.656e-19 1.00
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 3.177e-19 1.00
E2AK4_HUMAN EIF2AK4 eIF-2-alpha kinase GCN2 4.048e-19 1.00
BMR1B_HUMAN BMPR1B Bone morphogenetic protein receptor type-1B 5.613e-19 1.00
KKCC2_HUMAN CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 1.96e-18 1.00
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 5.165e-18 1.00
PAK4_HUMAN PAK4 Serine/threonine-protein kinase PAK 4 7.469e-18 1.00
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 8.268e-18 1.00
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 1.173e-17 1.00
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 1.3e-17 1.00
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 2.497e-17 1.00
AURKB_HUMAN AURKB Aurora kinase B 3.396e-17 1.00
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 1.11e-16 1.00
NEK2_HUMAN NEK2 Serine/threonine-protein kinase Nek2 1.11e-16 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 2.22e-16 1.00
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 3.331e-16 1.00
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 6.661e-16 1.00
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 9.992e-16 1.00
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 1.221e-15 1.00
MATK_HUMAN MATK Megakaryocyte-associated tyrosine-protein kinase 1.554e-15 1.00
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 2.442e-15 1.00
PDPK1_HUMAN PDPK1 3-phosphoinositide-dependent protein kinase 1 9.104e-15 1.00
AAPK2_HUMAN PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 1.066e-14 1.00
MK07_HUMAN MAPK7 Mitogen-activated protein kinase 7 2.331e-14 1.00
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 2.387e-14 1.00
M3K11_HUMAN MAP3K11 Mitogen-activated protein kinase kinase kinase 11 2.387e-14 1.00
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 2.398e-14 1.00
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.785e-14 1.00
KCC1D_HUMAN CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 1.061e-13 1.00
GAK_HUMAN GAK Cyclin-G-associated kinase 1.338e-13 1.00
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 1.68e-13 1.00
KCC1A_HUMAN CAMK1 Calcium/calmodulin-dependent protein kinase type 1 4.003e-13 1.00
PHKG2_HUMAN PHKG2 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 4.663e-13 1.00
M3K9_HUMAN MAP3K9 Mitogen-activated protein kinase kinase kinase 9 7.123e-13 1.00
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 7.123e-13 1.00
E2AK2_HUMAN EIF2AK2 Interferon-induced, double-stranded RNA-activated protein kinase 9.288e-13 1.00
PLK2_HUMAN PLK2 Serine/threonine-protein kinase PLK2 1.319e-12 1.00
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 1.881e-12 1.00
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 6.418e-12 1.00
TSSK1_HUMAN TSSK1B Testis-specific serine/threonine-protein kinase 1 1.972e-11 1.00
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 3.738e-11 1.00
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 5.008e-11 1.00
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 1.784e-10 1.00
KS6A1_HUMAN RPS6KA1 Ribosomal protein S6 kinase alpha-1 2.471e-10 1.00
AKT2_HUMAN AKT2 RAC-beta serine/threonine-protein kinase 4.779e-10 1.00
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 2.282e-09 1.00
ALK_HUMAN ALK ALK tyrosine kinase receptor 2.622e-09 1.00
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 3.514e-09 1.00
PLK4_HUMAN PLK4 Serine/threonine-protein kinase PLK4 3.692e-09 1.00
KPCD1_HUMAN PRKD1 Serine/threonine-protein kinase D1 7.234e-09 1.00
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 9.386e-09 1.00
LCK_HUMAN LCK Tyrosine-protein kinase Lck 1.443e-08 1.00
AURKA_HUMAN AURKA Aurora kinase A 2.387e-08 1.00
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 3.73e-08 1.00
FER_HUMAN FER Tyrosine-protein kinase Fer 4.869e-08 1.00
KS6A5_HUMAN RPS6KA5 Ribosomal protein S6 kinase alpha-5 8.678e-08 1.00
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 8.678e-08 1.00
KCC2G_HUMAN CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 9.69e-08 1.00
KC1G3_HUMAN CSNK1G3 Casein kinase I isoform gamma-3 1.041e-07 1.00
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 1.267e-07 1.00
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 1.992e-07 1.00
DYRK2_HUMAN DYRK2 Dual specificity tyrosine-phosphorylation-regulated kinase 2 2.066e-07 1.00
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 2.404e-07 1.00
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 2.452e-07 1.00
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 2.569e-07 1.00
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 3.614e-07 1.00
BLK_HUMAN BLK Tyrosine-protein kinase Blk 4.152e-07 1.00
MERTK_HUMAN MERTK Tyrosine-protein kinase Mer 4.614e-07 1.00
HIPK2_HUMAN HIPK2 Homeodomain-interacting protein kinase 2 4.63e-07 1.00
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 6.689e-07 1.00
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 7.034e-07 1.00
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 8.94e-07 1.00
KC1G1_HUMAN CSNK1G1 Casein kinase I isoform gamma-1 9.831e-07 1.00
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 1.127e-06 1.00
KCC2B_HUMAN CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta 1.264e-06 1.00
BRSK1_HUMAN BRSK1 Serine/threonine-protein kinase BRSK1 1.533e-06 1.00
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 2.121e-06 1.00
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 2.15e-06 1.00
AAPK1_HUMAN PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 2.396e-06 1.00
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 2.46e-06 1.00
ST17A_HUMAN STK17A Serine/threonine-protein kinase 17A 3.192e-06 1.00
TYRO3_HUMAN TYRO3 Tyrosine-protein kinase receptor TYRO3 4.18e-06 1.00
FRK_HUMAN FRK Tyrosine-protein kinase FRK 4.358e-06 1.00
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 6.182e-06 1.00
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 6.185e-06 1.00
CDK7_HUMAN CDK7 Cyclin-dependent kinase 7 6.329e-06 1.00
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 8.923e-06 1.00
KC1G2_HUMAN CSNK1G2 Casein kinase I isoform gamma-2 9.17e-06 1.00
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 1.09e-05 1.00
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 1.31e-05 1.00
MINK1_HUMAN MINK1 Misshapen-like kinase 1 1.542e-05 1.00
KC1E_HUMAN CSNK1E Casein kinase I isoform epsilon 2.234e-05 1.00
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 2.824e-05 1.00
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 4.326e-05 1.00
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 4.326e-05 1.00
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 4.54e-05 1.00
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 5.828e-05 1.00
KC1A_HUMAN CSNK1A1 Casein kinase I isoform alpha 5.831e-05 1.00
WEE1_HUMAN WEE1 Wee1-like protein kinase 6.882e-05 1.00
MARK3_HUMAN MARK3 MAP/microtubule affinity-regulating kinase 3 7.546e-05 1.00
IKKA_HUMAN CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha 9.635e-05 1.00
DAPK3_HUMAN DAPK3 Death-associated protein kinase 3 9.845e-05 1.00
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 0.0001151 1.00
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 0.0001425 1.00
KPCD2_HUMAN PRKD2 Serine/threonine-protein kinase D2 0.0001733 1.00
HCK_HUMAN HCK Tyrosine-protein kinase HCK 0.0002125 1.00
PTK6_HUMAN PTK6 Protein-tyrosine kinase 6 0.0002361 1.00
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 0.0003052 1.00
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 0.0003739 1.00
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 0.000408 1.00
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 0.0005462 1.00
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 0.0006072 1.00
DYR1B_HUMAN DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.0006968 1.00
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 0.0008836 1.00
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 0.00102 1.00
M3K12_HUMAN MAP3K12 Mitogen-activated protein kinase kinase kinase 12 0.001145 1.00
KC1D_HUMAN CSNK1D Casein kinase I isoform delta 0.001233 1.00
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 0.001393 1.00
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 0.001424 1.00
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 0.001619 1.00
MET_HUMAN MET Hepatocyte growth factor receptor 0.003635 1.00
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 0.004518 1.00
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 0.004684 1.00
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 0.006277 1.00
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 0.00643 1.00
FGFR2_HUMAN FGFR2 Fibroblast growth factor receptor 2 0.009157 1.00
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 0.01018 1.00
INSR_HUMAN INSR Insulin receptor 0.01024 1.00
KPCT_HUMAN PRKCQ Protein kinase C theta type 0.01263 1.00
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 0.01292 1.00
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 0.01446 1.00
FGFR3_HUMAN FGFR3 Fibroblast growth factor receptor 3 0.01572 1.00
FAK1_HUMAN PTK2 Focal adhesion kinase 1 0.01588 1.00
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 0.01611 1.00
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 0.01655 1.00
MKNK2_HUMAN MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 0.01845 1.00
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 0.0185 1.00
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 0.0216 1.00
FGFR4_HUMAN FGFR4 Fibroblast growth factor receptor 4 0.02244 1.00
TTK_HUMAN TTK Dual specificity protein kinase TTK 0.03093 1.00
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 0.03697 1.00
NTRK1_HUMAN NTRK1 High affinity nerve growth factor receptor 0.03856 1.00
CDK4_HUMAN CDK4 Cyclin-dependent kinase 4 0.03992 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 0.04495 1.00
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 0.04961 1.00
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 0.09366 1.00
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 0.1093 1.00
PIM3_HUMAN PIM3 Serine/threonine-protein kinase pim-3 0.1273 1.00
PIM2_HUMAN PIM2 Serine/threonine-protein kinase pim-2 0.1318 1.00
KPCA_HUMAN PRKCA Protein kinase C alpha type 0.1414 1.00
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 0.1583 1.00
BTK_HUMAN BTK Tyrosine-protein kinase BTK 0.1983 1.00
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 0.2062 1.00
IRAK4_HUMAN IRAK4 Interleukin-1 receptor-associated kinase 4 0.2221 1.00
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 0.4188 1.00
JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 0.7753 1.00
ACES_HUMAN ACHE Acetylcholinesterase 0.8309 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9565 1.00
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 0.9732 1.00
VGFR1_MOUSE Flt1 Vascular endothelial growth factor receptor 1 1.603e-59 0.48
PGH1_RABIT PTGS1 Prostaglandin G/H synthase 1 1.229e-52 0.45
PGH2_RABIT PTGS2 Prostaglandin G/H synthase 2 7.847e-46 0.38
FGFR1_MOUSE Fgfr1 Fibroblast growth factor receptor 1 3.17e-38 0.30
VGFR2_MOUSE Kdr Vascular endothelial growth factor receptor 2 2.37e-33 0.48
MET_CANLF MET Hepatocyte growth factor receptor 1.145e-19 0.38
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 3.659e-17 0.35
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 1.221e-15 0.34
FGFR3_MOUSE Fgfr3 Fibroblast growth factor receptor 3 3.775e-15 0.29
FGFR4_MOUSE Fgfr4 Fibroblast growth factor receptor 4 3.775e-15 0.29
FGR_MOUSE Fgr Tyrosine-protein kinase Fgr 3.775e-15 0.29
ZAP70_MOUSE Zap70 Tyrosine-protein kinase ZAP-70 3.775e-15 0.29
Q25856_PLAFA PFG6PD Glucose-6-phosphate dehydrogenase 4.219e-15 0.42
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 2.198e-14 0.34
BMX_MOUSE Bmx Cytoplasmic tyrosine-protein kinase BMX 3.373e-13 0.29
EPHB2_MOUSE Ephb2 Ephrin type-B receptor 2 3.373e-13 0.29
LYN_MOUSE Lyn Tyrosine-protein kinase Lyn 3.373e-13 0.29
MET_MOUSE Met Hepatocyte growth factor receptor 3.373e-13 0.29
RON_MOUSE Mst1r Macrophage-stimulating protein receptor 3.373e-13 0.29
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 6.303e-12 0.60
ALK_MOUSE Alk ALK tyrosine kinase receptor 8.485e-12 0.29
EPHA3_MOUSE Epha3 Ephrin type-A receptor 3 8.485e-12 0.29
MK09_MOUSE Mapk9 Mitogen-activated protein kinase 9 8.485e-12 0.29
RET_MOUSE Ret Proto-oncogene tyrosine-protein kinase receptor Ret 8.485e-12 0.29
ROS1_MOUSE Ros1 Proto-oncogene tyrosine-protein kinase ROS 8.485e-12 0.29
TIE1_MOUSE Tie1 Tyrosine-protein kinase receptor Tie-1 8.485e-12 0.29
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 1.804e-11 0.30
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 2.741e-11 0.36
KSYK_RAT Syk Tyrosine-protein kinase SYK 4.282e-11 0.30
FLT3_MOUSE Flt3 Receptor-type tyrosine-protein kinase FLT3 9.79e-11 0.29
PI3R5_HUMAN PIK3R5 Phosphoinositide 3-kinase regulatory subunit 5 1.105e-10 0.29
MGAT2_MOUSE Mgat2 Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase 1.272e-10 0.28
O96526_LEIMA CRK3 Cdc2-related kinase 1.517e-10 0.31
KIT_MOUSE Kit Mast/stem cell growth factor receptor Kit 6.75e-10 0.29
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 1.812e-09 0.36
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.881e-08 0.33
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 5.914e-08 0.36
CCNB1_HUMAN CCNB1 G2/mitotic-specific cyclin-B1 7.108e-08 0.38
INSR_MOUSE Insr Insulin receptor 9.468e-08 0.29
MGAT3_HUMAN MGAT3 Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase 5.363e-07 0.28
PDIA1_HUMAN P4HB Protein disulfide-isomerase 9.468e-07 0.31
CCNE1_HUMAN CCNE1 G1/S-specific cyclin-E1 4.14e-06 0.42

Budesonide

GCR_RAT Nr3c1 Glucocorticoid receptor 6.093e-66 1.00
Q690N0_BOVIN PGR Progesterone receptor 1.5e-50 1.00
GCR_HUMAN NR3C1 Glucocorticoid receptor 1.001e-35 1.00
MCR_HUMAN NR3C2 Mineralocorticoid receptor 3.707e-05 1.00
ANDR_RAT Ar Androgen receptor 0.0001424 1.00
PRGR_HUMAN PGR Progesterone receptor 0.003599 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.6015 1.00
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 0.789 1.00
ATTY_RAT Tat Tyrosine aminotransferase 6.582e-89 0.35
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.434e-48 0.57
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.023e-32 0.57
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.203e-21 0.35
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.485e-17 0.57
GLNA_HUMAN GLUL Glutamine synthetase 1.485e-17 0.57
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.055e-14 0.35
IL6_HUMAN IL6 Interleukin-6 6.029e-14 0.57
SHBG_HUMAN SHBG Sex hormone-binding globulin 3.456e-12 0.41
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 9.761e-09 0.35
CP19A_HUMAN CYP19A1 Aromatase 4.915e-08 0.36
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.966e-07 0.35

Chlorprothixene

PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 9.071e-62 1.00
HRH1_RAT Hrh1 Histamine H1 receptor 5.081e-18 1.00
DRD5_HUMAN DRD5 D(1B) dopamine receptor 1.424e-10 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 4.114e-08 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 3.197e-06 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 3.492e-05 1.00
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 0.001006 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.01063 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.01232 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 0.1811 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.2022 1.00
PRIO_MOUSE Prnp Major prion protein 1.218e-57 0.46
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 1.005e-25 0.46
TYTR_TRYCR TPR Trypanothione reductase 1.412e-20 0.46
CALM_BOVIN CALM Calmodulin 1.11e-16 0.46
HRH1_CAVPO HRH1 Histamine H1 receptor 1.11e-15 0.46
ASM_HUMAN SMPD1 Sphingomyelin phosphodiesterase 1.463e-13 0.33
CALM1_HUMAN CALM1 Calmodulin-1 1.302e-12 0.46
ELOB_HUMAN ELOB Elongin-B 7.541e-10 0.29
ELOC_HUMAN ELOC Elongin-C 7.541e-10 0.29
STE24_YEAST STE24 CAAX prenyl protease 1 1.397e-09 0.58
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 4.721e-09 0.51
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 4.765e-09 0.30
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 1.766e-08 0.46
B2LA1_MOUSE Bcl2a1 Bcl-2-related protein A1 2.763e-08 0.58
UR2R_HUMAN UTS2R Urotensin-2 receptor 1.491e-07 0.33
DRD1_RAT Drd1 D(1A) dopamine receptor 4.275e-07 0.46
TYTR_TRYBB TPR Trypanothione reductase 4.854e-07 0.32
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 7.834e-07 0.46
RCE1_YEAST RCE1 CAAX prenyl protease 2 1.446e-06 0.58
HRH2_HUMAN HRH2 Histamine H2 receptor 3.119e-06 0.51
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 3.838e-06 0.32
DPOL_VACCW POL DNA polymerase 3.933e-06 0.30
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 8.358e-06 0.51

Clomipramine

TYTR_TRYCR TPR Trypanothione reductase 2.528e-54 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 2.158e-32 1.00
TYTR_TRYBB TPR Trypanothione reductase 6.414e-29 1.00
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 7.819e-26 1.00
HRH1_RAT Hrh1 Histamine H1 receptor 3.732e-24 1.00
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 3.749e-20 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 6.229e-18 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.11e-16 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 4.441e-16 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 3.109e-15 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 3.886e-15 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 6.929e-13 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 1.862e-11 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 2.053e-11 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 2.177e-11 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 7.146e-11 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 8.859e-10 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 9.455e-10 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.537e-09 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.25e-09 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 4.873e-09 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 7.084e-09 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 2.55e-08 1.00
DRD2_RAT Drd2 D(2) dopamine receptor 2.889e-08 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 7.057e-08 1.00
HRH2_CAVPO HRH2 Histamine H2 receptor 2.393e-07 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 2.917e-06 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 3.25e-06 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 7.383e-06 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 2.57e-05 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.0004091 1.00
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 0.0005339 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.001926 1.00
Q9WTR4_RAT Slc6a2 Transporter 0.005145 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.007198 1.00
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 0.06811 1.00
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 2.516e-101 0.63
PRIO_MOUSE Prnp Major prion protein 1.143e-78 0.63
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 1.278e-38 0.36
CALM_BOVIN CALM Calmodulin 9.236e-34 0.63
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 1.336e-27 0.63
CAC1S_HUMAN CACNA1S Voltage-dependent L-type calcium channel subunit alpha-1S 3.272e-27 0.37
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 8.725e-27 0.44
LYSC1_RAT Lyz1 Lysozyme C-1 3.656e-26 0.32
CALM1_HUMAN CALM1 Calmodulin-1 2.663e-25 0.63
5HT2C_CANLF HTR2C 5-hydroxytryptamine receptor 2C 6.243e-24 0.29
MAP1_STAAC map Methionine aminopeptidase 1.114e-23 0.29
BGLR_RAT Gusb Beta-glucuronidase 2.952e-20 0.32
EBPL_HUMAN EBPL Emopamil-binding protein-like 2.952e-20 0.32
ADA1A_MOUSE Adra1a Alpha-1A adrenergic receptor 4.879e-18 0.29
ADA1D_MOUSE Adra1d Alpha-1D adrenergic receptor 4.879e-18 0.29
DRD5_HUMAN DRD5 D(1B) dopamine receptor 1.23e-17 0.63
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.221e-15 0.63
ADA1B_MOUSE Adra1b Alpha-1B adrenergic receptor 4.441e-15 0.29
DRD3_MOUSE Drd3 D(3) dopamine receptor 4.441e-15 0.29
DRD4_HUMAN DRD4 D(4) dopamine receptor 3.65e-13 0.63
5HT2A_MOUSE Htr2a 5-hydroxytryptamine receptor 2A 9.303e-13 0.29
V1AR_MOUSE Avpr1a Vasopressin V1a receptor 1.832e-12 0.33
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 2.95e-12 0.29
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 4.84e-12 0.49
5HT1D_MOUSE Htr1d 5-hydroxytryptamine receptor 1D 9.7e-12 0.29
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.154e-11 0.53
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 2.357e-11 0.63
UR2R_HUMAN UTS2R Urotensin-2 receptor 3.498e-11 0.36
DRD4_MOUSE Drd4 D(4) dopamine receptor 5.096e-11 0.29
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.357e-10 0.49
SAHH_HUMAN AHCY Adenosylhomocysteinase 1.702e-10 0.31
5HT2B_MOUSE Htr2b 5-hydroxytryptamine receptor 2B 4.574e-10 0.29
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.234e-09 0.32
DRD1_RAT Drd1 D(1A) dopamine receptor 4.386e-09 0.63
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 9.523e-09 0.29
5HT2C_MOUSE Htr2c 5-hydroxytryptamine receptor 2C 1.322e-08 0.29
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.672e-08 0.37
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 4.354e-08 0.34
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 5.627e-08 0.46
CHLE_HORSE BCHE Cholinesterase 1.296e-07 0.46
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 1.771e-07 0.63
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 1.928e-07 0.35
DRD4_RAT Drd4 D(4) dopamine receptor 2.271e-07 0.30
HRH1_CAVPO HRH1 Histamine H1 receptor 4.272e-07 0.63
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 4.324e-07 0.29
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 5.391e-07 0.38
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 5.535e-07 0.63
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 5.632e-07 0.33
DPOL_VACCW POL DNA polymerase 2.444e-06 0.31
PRIO_HUMAN PRNP Major prion protein 2.483e-06 0.63
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 5.118e-06 0.63
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 5.139e-06 0.32

Mitoxantrone

3MG_HUMAN MPG DNA-3-methyladenine glycosylase 1.089e-50 1.00
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 3.937e-30 1.00
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.22e-15 1.00
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 5.418e-14 1.00
UBA3_HUMAN UBA3 NEDD8-activating enzyme E1 catalytic subunit 9.469e-13 1.00
ULA1_HUMAN NAE1 NEDD8-activating enzyme E1 regulatory subunit 6.498e-12 1.00
NSD2_HUMAN NSD2 Histone-lysine N-methyltransferase NSD2 1.867e-08 1.00
APEX1_HUMAN APEX1 DNA-(apurinic or apyrimidinic site) lyase 2.227e-07 1.00
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 7.439e-07 1.00
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 2.06e-05 1.00
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 0.0005506 1.00
Q7ZJM1_9HIV1 pol Integrase 0.0006355 1.00
ROS1_HUMAN ROS1 Proto-oncogene tyrosine-protein kinase ROS 0.0007265 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 0.01089 1.00
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 0.07354 1.00
PAX8_HUMAN PAX8 Paired box protein Pax-8 0.0884 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.1054 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.5554 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.6272 1.00
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 0.7112 1.00
BTK_HUMAN BTK Tyrosine-protein kinase BTK 0.7268 1.00
PIM1_HUMAN PIM1 Serine/threonine-protein kinase pim-1 0.9271 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.9383 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.9572 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 0.9998 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9999 1.00
AL1A7_RAT Aldh1a7 Aldehyde dehydrogenase, cytosolic 1 5.245e-27 0.33
FIBB_HUMAN FGB Fibrinogen beta chain 1.133e-17 0.49
DPO1_THEAQ polA DNA polymerase I, thermostable 5.294e-09 0.35
Q9BEG3_BOVIN 5-lipoxygenase 8.898e-08 0.36
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 1.711e-06 0.37
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 9.449e-06 0.31

Paliperidone

5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.09e-44 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.031e-19 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 7.833e-07 1.00
ALBU_BOVIN ALB Serum albumin 5.388e-114 0.42
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 2.496e-52 0.75
DRD2_RAT Drd2 D(2) dopamine receptor 1.597e-43 0.75
H10_HUMAN H1-0 Histone H1.0 4.749e-38 0.75
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 5.913e-23 0.75
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.797e-18 0.75
ACOD_HUMAN SCD Acyl-CoA desaturase 3.524e-17 0.42
HRH1_CAVPO HRH1 Histamine H1 receptor 1.11e-16 0.75
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.22e-16 0.75
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 3.331e-16 0.75
CCR3_RAT Ccr3 C-C chemokine receptor type 3 1.554e-15 0.30
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 5.329e-15 0.75
CCR3_MOUSE Ccr3 Probable C-C chemokine receptor type 3 1.573e-13 0.30
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 4.956e-13 0.48
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 6.254e-12 0.29
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 1.189e-11 0.75
ACOD1_RAT Scd1 Acyl-CoA desaturase 1 1.236e-11 0.39
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 9.478e-11 0.75
DRD3_RAT Drd3 D(3) dopamine receptor 1.627e-10 0.75
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 2.313e-10 0.75
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 3.677e-10 0.75
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.221e-08 0.75
DRD1_MOUSE Drd1 D(1A) dopamine receptor 1.495e-08 0.46
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 2.705e-08 0.75
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 2.923e-08 0.75
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 3.892e-08 0.75
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 4.69e-08 0.75
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 7.799e-08 0.29
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 8.812e-08 0.48
DRD1_RAT Drd1 D(1A) dopamine receptor 3.567e-07 0.75
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 4.536e-07 0.75
HRH1_RAT Hrh1 Histamine H1 receptor 5.78e-07 0.75
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 3.464e-06 0.75
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 3.945e-06 0.36
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 4.024e-06 0.75

Chloroxine

LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.533e-43 1.00
Q8IL32_PLAF7 Heat shock protein 90, putative 4.04e-35 1.00
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 3.65e-20 1.00
STRP_STRP1 ska Streptokinase A 5.551e-16 1.00
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 0.0001383 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 0.05486 1.00
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 0.3362 1.00
AMPL_YEAST APE1 Vacuolar aminopeptidase 1 2.443e-64 0.51
ATS5_HUMAN ADAMTS5 A disintegrin and metalloproteinase with thrombospondin motifs 5 1.99e-49 0.44
BXA1_CLOBO botA Botulinum neurotoxin type A 1.718e-42 0.59
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 6.803e-39 0.62
S40A1_HUMAN SLC40A1 Solute carrier family 40 member 1 1.264e-36 0.41
BXA1_CLOBH botA Botulinum neurotoxin type A 6.402e-30 0.51
LMP1_EBVB9 LMP1 Latent membrane protein 1 1.579e-25 0.50
COMT_RAT Comt Catechol O-methyltransferase 4.417e-25 0.72
Q7ZJM1_9HIV1 pol Integrase 6.768e-20 0.38
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 2.284e-18 0.34
A3KMY8_BOVIN GUSB Beta-glucuronidase 3.31e-17 0.38
CAH1_HORSE CA1 Carbonic anhydrase 1 1.11e-16 0.29
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 5.551e-16 0.40
AMPX_VIBPR Bacterial leucyl aminopeptidase 6.661e-16 0.39
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 1.554e-15 0.38
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 3.664e-15 0.35
EZRI_HUMAN EZR Ezrin 4.431e-13 0.32
COMT_HUMAN COMT Catechol O-methyltransferase 3.101e-12 0.39
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 2.669e-11 0.59
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 1.035e-09 0.55
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 2.569e-09 0.34
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 3.133e-09 0.32
VP16_HHV11 Tegument protein VP16 5.047e-09 0.52
KLF5_HUMAN KLF5 Krueppel-like factor 5 1.206e-08 0.50
PP1A_HUMAN PPP1CA Serine/threonine-protein phosphatase PP1-alpha catalytic subunit 2.068e-08 0.48
T23O_MOUSE Tdo2 Tryptophan 2,3-dioxygenase 3.119e-08 0.42
Q76353_9HIV1 Integrase 4.165e-08 0.34
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 2.52e-07 0.40
CYSP_PLAFA Trophozoite cysteine proteinase 2.781e-07 0.30
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 3.299e-07 0.38
KAT2B_HUMAN KAT2B Histone acetyltransferase KAT2B 6.855e-07 0.33
MITF_HUMAN MITF Microphthalmia-associated transcription factor 7.565e-07 0.40
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 3.907e-06 0.53
EP300_HUMAN EP300 Histone acetyltransferase p300 4.004e-06 0.31
EGLN1_HUMAN EGLN1 Egl nine homolog 1 5.133e-06 0.35
MPI_HUMAN MPI Mannose-6-phosphate isomerase 5.387e-06 0.51
GCN5_YEAST GCN5 Histone acetyltransferase GCN5 7.112e-06 0.29
CAH15_MOUSE Ca15 Carbonic anhydrase 15 7.447e-06 0.72
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 7.962e-06 0.38
I23O1_MOUSE Ido1 Indoleamine 2,3-dioxygenase 1 8.374e-06 0.42
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 9.446e-06 0.50

Diphenidol

SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.658e-43 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.491e-26 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 9.007e-26 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.082e-24 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 4.257e-24 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.496e-23 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 4.112e-22 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 2.944e-13 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.7e-12 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.339e-10 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.257e-06 1.00
HNMT_RAT Hnmt Histamine N-methyltransferase 2.445e-100 0.41
HRH3_HUMAN HRH3 Histamine H3 receptor 2.188e-92 0.48
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 2.403e-90 0.38
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 3.322e-60 0.45
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.345e-54 0.54
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 4.905e-45 0.41
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 5.369e-45 0.36
HRH3_MOUSE Hrh3 Histamine H3 receptor 1.156e-42 0.48
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 2.641e-41 0.53
ABHDB_HUMAN ABHD11 Protein ABHD11 5.602e-40 0.34
HRH3_CAVPO HRH3 Histamine H3 receptor 1.005e-38 0.46
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 4.794e-38 0.51
DGLB_MOUSE Daglb Sn1-specific diacylglycerol lipase beta 7.066e-38 0.31
EBPL_HUMAN EBPL Emopamil-binding protein-like 2.692e-36 0.30
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 4.225e-35 0.37
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 4.733e-35 0.45
CHLE_MOUSE Bche Cholinesterase 2.527e-34 0.33
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 4.986e-31 0.38
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 6.987e-31 0.42
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.278e-30 0.31
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 1.623e-28 0.41
MEN1_HUMAN MEN1 Menin 1.17e-27 0.39
HRH3_RAT Hrh3 Histamine H3 receptor 5.878e-26 0.41
LYSC1_RAT Lyz1 Lysozyme C-1 2.962e-24 0.30
NORA_STAAU norA Quinolone resistance protein NorA 5.018e-24 0.36
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 5.873e-22 0.43
CALM_BOVIN CALM Calmodulin 1.145e-21 0.31
HRH1_HUMAN HRH1 Histamine H1 receptor 3.297e-21 0.43
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 4.423e-19 0.47
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 5.628e-19 0.32
BGLR_RAT Gusb Beta-glucuronidase 8.596e-19 0.30
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 9.119e-19 0.31
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 1.084e-18 0.41
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 1.21e-18 0.43
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.11e-16 0.42
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 1.11e-16 0.37
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 3.331e-16 0.32
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 4.441e-16 0.31
ERG2_YEAST ERG2 C-8 sterol isomerase 1.554e-15 0.32
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.998e-15 0.35
Q6L5J4_HUMAN FPRL2 FML2_HUMAN 7.849e-14 0.35
ACES_MOUSE Ache Acetylcholinesterase 8.027e-14 0.32
LYPA2_HUMAN LYPLA2 Acyl-protein thioesterase 2 8.138e-14 0.34
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 2.477e-13 0.37
ACES_ELEEL ache Acetylcholinesterase 3.257e-13 0.34
TYTR_TRYBB TPR Trypanothione reductase 3.39e-13 0.32
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 3.982e-13 0.38
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 4.055e-13 0.40
OPRX_MOUSE Oprl1 Nociceptin receptor 6.108e-13 0.28
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 6.41e-13 0.38
LYPA1_HUMAN LYPLA1 Acyl-protein thioesterase 1 1.465e-12 0.34
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 2.013e-12 0.30
B6TK44_MAIZE Cycloeucalenol cycloisomerase 3.325e-12 0.30
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 4.485e-12 0.37
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 4.586e-12 0.45
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 6.312e-12 0.49
DPOL_VACCW POL DNA polymerase 7.155e-12 0.33
CHLE_HORSE BCHE Cholinesterase 1.019e-11 0.34
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.127e-11 0.33
US28_HCMVA US28 G-protein coupled receptor homolog US28 1.92e-11 0.31
ABHD6_HUMAN ABHD6 Monoacylglycerol lipase ABHD6 2.076e-11 0.31
ACHA6_RAT Chrna6 Neuronal acetylcholine receptor subunit alpha-6 2.414e-11 0.32
B4FS76_MAIZE 100281352 Delta(14)-sterol reductase 4.196e-11 0.30
Q2TU57_MAIZE Sterol-8,7-isomerase 4.196e-11 0.30
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 6.552e-11 0.30
HRH1_CAVPO HRH1 Histamine H1 receptor 1.049e-10 0.38
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.351e-10 0.37
Q63380_RAT NET Transporter 1.478e-10 0.31
PYGL_RAT Pygl Glycogen phosphorylase, liver form 1.701e-10 0.31
DRD4_RAT Drd4 D(4) dopamine receptor 1.745e-10 0.33
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 1.98e-10 0.29
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 1.989e-10 0.33
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 2.218e-10 0.41
DRD2_RAT Drd2 D(2) dopamine receptor 3.513e-10 0.49
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 4.266e-10 0.38
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 4.715e-10 0.32
VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 5.982e-10 0.29
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 7.966e-10 0.38
DRD5_HUMAN DRD5 D(1B) dopamine receptor 9.324e-10 0.39
HRH2_HUMAN HRH2 Histamine H2 receptor 1.217e-09 0.35
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 4.372e-09 0.32
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 4.626e-09 0.40
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 5.525e-09 0.35
DPO1_THEAQ polA DNA polymerase I, thermostable 7.906e-09 0.36
NPSR1_HUMAN NPSR1 Neuropeptide S receptor 1.008e-08 0.31
ACES_HUMAN ACHE Acetylcholinesterase 1.75e-08 0.36
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.868e-08 0.41
CALM1_HUMAN CALM1 Calmodulin-1 1.896e-08 0.30
ACHP_LYMST Acetylcholine-binding protein 2.15e-08 0.35
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 2.194e-08 0.35
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 3.875e-08 0.41
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 4.697e-08 0.41
TERT_HUMAN TERT Telomerase reverse transcriptase 4.818e-08 0.36
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 7.847e-08 0.31
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 9.736e-08 0.35
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 1.976e-07 0.30
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 2.01e-07 0.29
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 2.036e-07 0.29
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 2.224e-07 0.35
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 3.775e-07 0.30
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 4.099e-07 0.48
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 4.763e-07 0.33
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 8.194e-07 0.32
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 9.422e-07 0.31
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 9.882e-07 0.34
O97467_PLAFA ht1 Hexose transporter 1 1.226e-06 0.32
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 1.657e-06 0.31
LMBL3_HUMAN L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 1.689e-06 0.33
CHLE_HUMAN BCHE Cholinesterase 1.708e-06 0.35
DRD1_HUMAN DRD1 D(1A) dopamine receptor 2.91e-06 0.39
DUT_HUMAN DUT Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial 3.108e-06 0.29
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 3.575e-06 0.29
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 3.628e-06 0.38
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 4.9e-06 0.34
DRD2_BOVIN DRD2 D(2) dopamine receptor 4.92e-06 0.33
CASP5_HUMAN CASP5 Caspase-5 5.02e-06 0.29
LMBL1_HUMAN L3MBTL1 Lethal(3)malignant brain tumor-like protein 1 6.631e-06 0.30
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 7.718e-06 0.35
ACES_ANOGA Ace Acetylcholinesterase 7.962e-06 0.38
O61059_LEIME LmGT2 Glucose transporter 8.585e-06 0.32
Q25856_PLAFA PFG6PD Glucose-6-phosphate dehydrogenase 9.736e-06 0.29

Paclitaxel

TBB3_HUMAN TUBB3 Tubulin beta-3 chain 4.629e-39 1.00
Q25270_LEIDO beta-tubulin Beta-tubulin 4.197e-20 1.00
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 3.307e-11 1.00
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 0.0002285 1.00
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 0.0004316 1.00
BXA1_CLOBO botA Botulinum neurotoxin type A 0.0007443 1.00
MERTK_HUMAN MERTK Tyrosine-protein kinase Mer 0.0008578 1.00
NK2R_HUMAN TACR2 Substance-K receptor 0.008848 1.00
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 0.01418 1.00
ITAV_HUMAN ITGAV Integrin alpha-V 0.08047 1.00
ITB3_HUMAN ITGB3 Integrin beta-3 0.4299 1.00
OPRD_HUMAN OPRD1 Delta-type opioid receptor 0.9836 1.00
GHRHR_HUMAN GHRHR Growth hormone-releasing hormone receptor 1.335e-95 0.77
UB2D3_HUMAN UBE2D3 Ubiquitin-conjugating enzyme E2 D3 1.242e-13 0.30
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 6.192e-07 0.30

Varenicline

ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 5.469e-39 1.00
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 1.734e-37 1.00
ACHB2_RAT Chrnb2 Neuronal acetylcholine receptor subunit beta-2 6.257e-21 1.00
ACHA4_RAT Chrna4 Neuronal acetylcholine receptor subunit alpha-4 2.043e-20 1.00
ACHB3_RAT Chrnb3 Neuronal acetylcholine receptor subunit beta-3 2.176e-19 1.00
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 2.22e-16 1.00
ACHA3_HUMAN CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 2.998e-15 1.00
ACHA6_RAT Chrna6 Neuronal acetylcholine receptor subunit alpha-6 2.589e-12 1.00
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 5.337e-07 1.00
ACHA3_RAT Chrna3 Neuronal acetylcholine receptor subunit alpha-3 1.446e-06 1.00
ACHB4_RAT Chrnb4 Neuronal acetylcholine receptor subunit beta-4 1.501e-06 1.00
ACHA2_RAT Chrna2 Neuronal acetylcholine receptor subunit alpha-2 2.86e-05 1.00
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 0.001986 1.00
TRXR2_PLAF7 trxr2 Thioredoxin reductase 2 2.492e-12 0.33
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 6.574e-12 0.47
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 1.509e-11 0.47
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 2.536e-11 0.47
ACHA_HUMAN CHRNA1 Acetylcholine receptor subunit alpha 6.215e-10 0.47

Pergolide

DRD2_BOVIN DRD2 D(2) dopamine receptor 1.589e-37 1.00
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 5.921e-10 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.175e-09 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 2.803e-09 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 2.098e-07 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 6.1e-07 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 4.133e-06 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 6.004e-06 1.00
DRD2_RAT Drd2 D(2) dopamine receptor 6.637e-06 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.48e-05 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 1.959e-05 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 3.03e-05 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 0.0001033 1.00
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 0.0004408 1.00
DRD3_RAT Drd3 D(3) dopamine receptor 0.0004504 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.01047 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.01107 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.03045 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.03587 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.08853 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.1206 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9999 1.00
CXCR3_MOUSE Cxcr3 C-X-C chemokine receptor type 3 1.563e-34 0.33
CXCR3_RAT Cxcr3 C-X-C chemokine receptor type 3 1.197e-24 0.33
DRD1_MOUSE Drd1 D(1A) dopamine receptor 1.953e-19 0.37
GRP1_RAT Rasgrp1 RAS guanyl-releasing protein 1 1.11e-16 0.32
SSR1_RAT Sstr1 Somatostatin receptor type 1 1.11e-16 0.43
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 2.329e-12 0.44
SSR2_RAT Sstr2 Somatostatin receptor type 2 7.913e-12 0.43
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 2.329e-10 0.37
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 2.661e-09 0.40
DRD5_HUMAN DRD5 D(1B) dopamine receptor 7.136e-07 0.37
DRD1_RAT Drd1 D(1A) dopamine receptor 2.111e-06 0.52
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 9.61e-06 0.34

Domperidone

ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.93e-32 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 6.488e-30 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.453e-26 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 2.512e-20 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.085e-19 1.00
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 3.331e-16 1.00
DRD2_RAT Drd2 D(2) dopamine receptor 4.441e-16 1.00
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.22e-15 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 2.32e-14 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 1.386e-08 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 7.47e-08 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 3.484e-06 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 7.153e-06 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.292e-05 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 2.631e-05 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 4.394e-05 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 6.997e-05 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 0.0006126 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.0009917 1.00
DRD3_RAT Drd3 D(3) dopamine receptor 0.001446 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.004678 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.005899 1.00
RXRA_HUMAN RXRA Retinoic acid receptor RXR-alpha 0.02613 1.00
PLD1_RAT Pld1 Phospholipase D1 4.723e-172 0.58
PLD1_HUMAN PLD1 Phospholipase D1 2.426e-160 0.62
PLD2_HUMAN PLD2 Phospholipase D2 1.077e-153 0.58
RMLC_MYCTO rmlC dTDP-4-dehydrorhamnose 3,5-epimerase 8.495e-84 0.36
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 2.112e-68 0.62
OPRX_HUMAN OPRL1 Nociceptin receptor 1.486e-42 0.60
CALRL_HUMAN CALCRL Calcitonin gene-related peptide type 1 receptor 7.971e-39 0.39
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 7.276e-28 0.66
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 7.691e-27 0.64
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.356e-26 0.58
HRH3_CAVPO HRH3 Histamine H3 receptor 1.563e-24 0.48
DRD2_BOVIN DRD2 D(2) dopamine receptor 1.46e-22 0.58
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 5.285e-22 0.59
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.938e-20 0.66
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 2.483e-20 0.35
DPO3_BACSU polC DNA polymerase III PolC-type 6.019e-20 0.31
THAS_RAT Tbxas1 Thromboxane-A synthase 2.729e-18 0.36
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 7.966e-18 0.58
AKT2_HUMAN AKT2 RAC-beta serine/threonine-protein kinase 1.11e-16 0.47
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.11e-16 0.38
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 5.551e-16 0.59
V1AR_MOUSE Avpr1a Vasopressin V1a receptor 7.772e-16 0.52
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.776e-15 0.58
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 2.442e-15 0.45
KAPCA_RAT Prkaca cAMP-dependent protein kinase catalytic subunit alpha 5.662e-15 0.28
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 3.364e-14 0.46
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 6.55e-14 0.34
DRD3_CHLAE DRD3 D(3) dopamine receptor 1.92e-13 0.49
OPRX_MOUSE Oprl1 Nociceptin receptor 2.289e-13 0.29
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 6.405e-13 0.30
S6A12_HUMAN SLC6A12 Sodium- and chloride-dependent betaine transporter 7.834e-13 0.31
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 2.67e-12 0.38
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 8.263e-12 0.36
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.581e-11 0.53
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 2.54e-11 0.67
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 7.119e-11 0.56
Q6Q253_PIG 5-HT4R 5-hydroxytryptamine receptor 4 protein 8.191e-11 0.29
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 8.958e-11 0.34
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 1.309e-10 0.47
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 1.422e-10 0.33
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.434e-10 0.47
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 2.205e-10 0.58
DRD4_RAT Drd4 D(4) dopamine receptor 2.487e-10 0.58
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.953e-10 0.51
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 4.787e-10 0.40
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 5.384e-10 0.35
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 5.444e-10 0.33
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 5.65e-10 0.48
AKT3_HUMAN AKT3 RAC-gamma serine/threonine-protein kinase 7.763e-10 0.43
CALRL_RAT Calcrl Calcitonin gene-related peptide type 1 receptor 1.007e-09 0.33
CATS_HUMAN CTSS Cathepsin S 1.415e-09 0.48
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 2.177e-09 0.51
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 3.292e-09 0.31
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 4.298e-09 0.34
SCRB1_HUMAN SCARB1 Scavenger receptor class B member 1 8.942e-09 0.30
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 9.124e-09 0.58
DRD2_CHLAE DRD2 D(2) dopamine receptor 1.547e-08 0.49
ACHP_LYMST Acetylcholine-binding protein 6.351e-08 0.31
HRH1_RAT Hrh1 Histamine H1 receptor 9.378e-08 0.31
HRH1_CAVPO HRH1 Histamine H1 receptor 1.201e-07 0.51
OPRD_HUMAN OPRD1 Delta-type opioid receptor 6.165e-07 0.58
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 6.44e-07 0.48
CCR3_MOUSE Ccr3 Probable C-C chemokine receptor type 3 6.689e-07 0.28
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 7.427e-07 0.30
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 9.31e-07 0.34
NK2R_HUMAN TACR2 Substance-K receptor 1.078e-06 0.46
ACLY_HUMAN ACLY ATP-citrate synthase 1.341e-06 0.29
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 1.355e-06 0.58
PAX8_HUMAN PAX8 Paired box protein Pax-8 1.705e-06 0.42
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 2.094e-06 0.31
WEE1_HUMAN WEE1 Wee1-like protein kinase 2.222e-06 0.32
OXDA_PIG DAO D-amino-acid oxidase 2.712e-06 0.33
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 2.911e-06 0.58
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 5.984e-06 0.54
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 7.833e-06 0.34
RAMP1_HUMAN RAMP1 Receptor activity-modifying protein 1 7.936e-06 0.36
DRD1_HUMAN DRD1 D(1A) dopamine receptor 9.352e-06 0.53
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 9.531e-06 0.30

Acebutolol

ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 2.316e-32 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 0.00823 1.00
ADRB2_MOUSE Adrb2 Beta-2 adrenergic receptor 9.88e-98 0.44
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 1.829e-95 0.52
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 8.188e-80 0.52
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 5.864e-63 0.52
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 9.614e-63 0.46
TERT_HUMAN TERT Telomerase reverse transcriptase 3.192e-43 0.34
MSRE_MOUSE Msr1 Macrophage scavenger receptor types I and II 7.528e-39 0.31
DNMT1_MOUSE Dnmt1 DNA (cytosine-5)-methyltransferase 1 1.497e-33 0.33
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 5.063e-33 0.46
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 8.365e-27 0.52
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.599e-20 0.45
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 2.202e-20 0.45
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 3.445e-18 0.29
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 1.72e-13 0.45
RXFP1_HUMAN RXFP1 Relaxin receptor 1 2.263e-13 0.32
LDLR_HUMAN LDLR Low-density lipoprotein receptor 2.337e-12 0.31
ITA3_HUMAN ITGA3 Integrin alpha-3 4.417e-12 0.29
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.238e-11 0.40
UT1_RAT Slc14a1 Urea transporter 1 4.073e-11 0.30
AOFB_RAT Maob Amine oxidase [flavin-containing] B 6.086e-11 0.36
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 1.32e-10 0.30
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.561e-10 0.31
PAR1_HUMAN F2R Proteinase-activated receptor 1 4.785e-10 0.38
PSBA_SPIOL psbA Photosystem II protein D1 1.609e-09 0.30
GLP1R_RAT Glp1r Glucagon-like peptide 1 receptor 2.247e-09 0.29
FDFT_RAT Fdft1 Squalene synthase 5.067e-09 0.56
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.298e-07 0.31
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.629e-07 0.30
GATA4_MOUSE Gata4 Transcription factor GATA-4 3.513e-07 0.29
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 3.513e-07 0.29
B4URF0_I33A0 Neuraminidase 5.869e-07 0.34
PRIO_SHEEP PRNP Major prion protein 1.316e-06 0.30
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 1.611e-06 0.30
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.32e-06 0.29
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 7.12e-06 0.31

Levobunolol

ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 6.214e-32 1.00
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 3.827e-25 1.00
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 4.99e-21 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 0.002339 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.02208 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.2868 1.00
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 5.434e-97 0.46
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 5.264e-93 0.46
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 7.581e-65 0.45
CASR_HUMAN CASR Extracellular calcium-sensing receptor 3.239e-57 0.43
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 7.594e-57 0.52
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 2.819e-49 0.52
CASR_BOVIN CASR Extracellular calcium-sensing receptor 8.334e-48 0.38
SCN9A_MOUSE Scn9a Sodium channel protein type 9 subunit alpha 2.071e-46 0.34
SCN1A_HUMAN SCN1A Sodium channel protein type 1 subunit alpha 1.447e-42 0.34
Q5YLN7_CANLF SCN5A Voltage-gated sodium channel Nav1.5 cardiac isoform 1.998e-41 0.33
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.395e-39 0.43
NAT_MYCSM nat Arylamine N-acetyltransferase 6.694e-38 0.30
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 2.338e-21 0.35
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 1.892e-18 0.36
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 4.992e-18 0.39
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 6.969e-18 0.36
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 1.573e-17 0.36
ACHA_HUMAN CHRNA1 Acetylcholine receptor subunit alpha 2.331e-15 0.36
MEP50_HUMAN WDR77 Methylosome protein 50 3.109e-15 0.35
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 4.441e-15 0.35
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 5.558e-13 0.32
ADRB2_MOUSE Adrb2 Beta-2 adrenergic receptor 1.532e-12 0.31
CASR_RAT Casr Extracellular calcium-sensing receptor 2.982e-11 0.38
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 3.122e-11 0.30
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 1.764e-07 0.39
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 2.1e-06 0.45
NR1H4_MOUSE Nr1h4 Bile acid receptor 4.225e-06 0.29

Escitalopram

Q63380_RAT NET Transporter 1.859e-31 1.00
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 6.103e-26 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 3.217e-12 1.00
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 4.781e-11 1.00
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 7.181e-08 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 0.0002947 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 0.03766 1.00
Q9WTR4_RAT Slc6a2 Transporter 0.1379 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.3224 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 0.3831 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.4773 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.5008 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.7812 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.9572 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.9676 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.9994 1.00
PNMT_BOVIN PNMT Phenylethanolamine N-methyltransferase 1.694e-08 0.32
PNMT_HUMAN PNMT Phenylethanolamine N-methyltransferase 8.874e-07 0.32

Decamethonium

ACHB_TETCF CHRNB1 Acetylcholine receptor subunit beta 3.59e-28 1.00
ACHG_TETCF CHRNG Acetylcholine receptor subunit gamma 3.59e-28 1.00
ACHD_TETCF chrnd Acetylcholine receptor subunit delta 4.419e-25 1.00
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 1.377e-17 1.00
ACES_MOUSE Ache Acetylcholinesterase 0.0005085 1.00
ACHB2_RAT Chrnb2 Neuronal acetylcholine receptor subunit beta-2 0.3527 1.00
ACHA4_RAT Chrna4 Neuronal acetylcholine receptor subunit alpha-4 0.3802 1.00
ACES_HUMAN ACHE Acetylcholinesterase 0.9519 1.00
HRH3_HUMAN HRH3 Histamine H3 receptor 0.9904 1.00
PLB1_CRYNB PLB1 Phospholipase B 1.142e-80 0.41
SC6A8_RAT Slc6a8 Sodium- and chloride-dependent creatine transporter 1 2.011e-55 0.35
DYN1_HUMAN DNM1 Dynamin-1 4.81e-55 0.73
BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 1.395e-20 0.43
SC5A7_MOUSE Slc5a7 High affinity choline transporter 1 4.463e-12 0.56
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 6.658e-11 0.41
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 6.636e-09 0.35
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 7.442e-08 0.35
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 3.65e-06 0.35

Moclobemide

5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 2.33e-26 1.00
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 1.766e-21 1.00
AOFB_RAT Maob Amine oxidase [flavin-containing] B 3.147e-08 1.00
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 0.005876 1.00
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 0.02663 1.00
PLD2_HUMAN PLD2 Phospholipase D2 2.536e-160 0.54
PLD1_HUMAN PLD1 Phospholipase D1 3.058e-141 0.54
PLD1_RAT Pld1 Phospholipase D1 3.881e-92 0.51
DRD1_PIG DRD1 D(1A) dopamine receptor 2.163e-84 0.46
DRD3_HUMAN DRD3 D(3) dopamine receptor 6.546e-76 0.54
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 3.424e-73 0.35
DRD4_RAT Drd4 D(4) dopamine receptor 2.163e-71 0.65
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 3.58e-71 0.37
DRD5_RAT Drd5 D(1B) dopamine receptor 3.765e-71 0.34
DRD4_HUMAN DRD4 D(4) dopamine receptor 3.606e-68 0.55
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.162e-64 0.62
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 2.336e-61 0.33
SYUA_HUMAN SNCA Alpha-synuclein 1.155e-58 0.36
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 7.811e-56 0.52
DRD3_RAT Drd3 D(3) dopamine receptor 6.424e-48 0.44
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 5.018e-47 0.51
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.187e-44 0.83
SC6A9_MOUSE Slc6a9 Sodium- and chloride-dependent glycine transporter 1 1.994e-44 0.33
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 2.604e-43 0.51
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 2.872e-42 0.47
CASR_MOUSE Casr Extracellular calcium-sensing receptor 5.166e-42 0.33
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 2.029e-41 0.62
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 4.995e-41 0.45
NK2R_HUMAN TACR2 Substance-K receptor 2.004e-40 0.40
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 2.735e-40 0.47
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 3.447e-39 0.50
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 4.761e-38 0.51
Q9MYJ9_RABIT CCR1 Chemokine receptor 2.707e-37 0.30
E2R517_CANLF GCGR Glucagon receptor 7.142e-37 0.29
DPOL_HHV11 DNA polymerase catalytic subunit 7.682e-36 0.41
DPOL_VZVD DNA polymerase catalytic subunit 7.682e-36 0.41
TLR9_HUMAN TLR9 Toll-like receptor 9 1.198e-35 0.34
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 2.478e-35 0.54
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 8.806e-35 0.38
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 4.802e-34 0.61
CASR_HUMAN CASR Extracellular calcium-sensing receptor 5.217e-34 0.35
CAC1I_HUMAN CACNA1I Voltage-dependent T-type calcium channel subunit alpha-1I 8.523e-33 0.37
HSPB1_HUMAN HSPB1 Heat shock protein beta-1 2.057e-32 0.34
5HT3B_MOUSE Htr3b 5-hydroxytryptamine receptor 3B 1.518e-31 0.40
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 3.294e-30 0.62
HNMT_RAT Hnmt Histamine N-methyltransferase 1.193e-29 0.30
Q38C41_TRYB2 Phosphotransferase 1.227e-29 0.31
SAHH_HUMAN AHCY Adenosylhomocysteinase 1.512e-28 0.34
COMT_PIG COMT Catechol O-methyltransferase 3.167e-28 0.33
ZN664_CAVPO ZNF664 Zinc finger protein 664 6.58e-28 0.34
CNR1_RAT Cnr1 Cannabinoid receptor 1 7.62e-28 0.41
MC5R_HUMAN MC5R Melanocortin receptor 5 1.224e-27 0.41
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 3.964e-27 0.54
ENL_HUMAN MLLT1 Protein ENL 5.245e-27 0.33
CNR2_HUMAN CNR2 Cannabinoid receptor 2 1.327e-26 0.45
CNR1_HUMAN CNR1 Cannabinoid receptor 1 3.684e-26 0.40
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 4.915e-26 0.38
HRH3_HUMAN HRH3 Histamine H3 receptor 1.29e-25 0.51
B2CL1_HUMAN BCL2L1 Bcl-2-like protein 1 4.393e-25 0.42
Q9X688_CAUVI cckA Cell cycle histidine kinase CckA 7.913e-25 0.31
ADCY5_RAT Adcy5 Adenylate cyclase type 5 9.103e-25 0.35
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 2.739e-24 0.41
IMA1_HUMAN KPNA2 Importin subunit alpha-1 4.212e-24 0.30
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 6.23e-24 0.50
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 9.979e-24 0.53
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.266e-23 0.62
C6ARS9_RHILS lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 3.619e-23 0.37
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 4.436e-23 0.37
BCL2_HUMAN BCL2 Apoptosis regulator Bcl-2 1.139e-21 0.42
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 1.606e-21 0.39
HRH3_CAVPO HRH3 Histamine H3 receptor 4.36e-21 0.55
LPXC_ECOLI lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 7.205e-21 0.37
HRP1_PLAFA Histidine-rich protein PFHRP-II 1.523e-20 0.39
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 1.558e-20 0.41
GLR_RAT Gcgr Glucagon receptor 2.384e-20 0.30
AUKBA_XENLA aurkb-a Aurora kinase B-A 4.22e-20 0.32
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 4.985e-20 0.33
GPC6A_MOUSE Gprc6a G-protein coupled receptor family C group 6 member A 6e-20 0.32
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 1.051e-19 0.38
ITB2_HUMAN ITGB2 Integrin beta-2 1.177e-19 0.37
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 1.24e-19 0.40
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 1.869e-19 0.41
Q9HUN3_PSEAE dnaB Replicative DNA helicase 2.146e-19 0.43
FA10_HUMAN F10 Coagulation factor X 2.497e-19 0.45
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 2.512e-19 0.39
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 3.399e-19 0.42
GIPR_HUMAN GIPR Gastric inhibitory polypeptide receptor 6.938e-19 0.31
Q8DNV6_STRR6 murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 9.538e-19 0.30
GLR_HUMAN GCGR Glucagon receptor 1.235e-18 0.33
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 2.119e-18 0.51
GIPR_RAT Gipr Gastric inhibitory polypeptide receptor 2.139e-18 0.29
ACES_MOUSE Ache Acetylcholinesterase 2.491e-18 0.48
HDAC6_HUMAN HDAC6 Histone deacetylase 6 3.346e-18 0.55
USP9X_HUMAN USP9X Probable ubiquitin carboxyl-terminal hydrolase FAF-X 3.809e-18 0.29
H10_HUMAN H1-0 Histone H1.0 5.03e-18 0.34
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 5.335e-18 0.35
TAAR1_RAT Taar1 Trace amine-associated receptor 1 5.402e-18 0.39
Q25856_PLAFA PFG6PD Glucose-6-phosphate dehydrogenase 5.529e-18 0.36
DRD2_RAT Drd2 D(2) dopamine receptor 5.742e-18 0.58
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 1.016e-17 0.45
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 1.419e-17 0.37
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 2.915e-17 0.32
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 3.175e-17 0.53
ICAM1_HUMAN ICAM1 Intercellular adhesion molecule 1 5.369e-17 0.46
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 1.11e-16 0.42
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 1.11e-16 0.35
ITAL_HUMAN ITGAL Integrin alpha-L 1.11e-16 0.37
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 2.22e-16 0.37
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 3.331e-16 0.51
SC5A7_HUMAN SLC5A7 High affinity choline transporter 1 4.441e-16 0.37
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 5.551e-16 0.40
SCNAA_HUMAN SCN10A Sodium channel protein type 10 subunit alpha 6.661e-16 0.41
THAS_RAT Tbxas1 Thromboxane-A synthase 6.661e-16 0.46
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 7.772e-16 0.50
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 8.882e-16 0.50
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 8.882e-16 0.35
M3K8_HUMAN MAP3K8 Mitogen-activated protein kinase kinase kinase 8 1.221e-15 0.36
5HT1B_GORGO HTR1B 5-hydroxytryptamine receptor 1B 1.443e-15 0.30
PA_I000X PA Polymerase acidic protein 1.887e-15 0.29
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 3.109e-15 0.29
Q9WTR4_RAT Slc6a2 Transporter 5.107e-15 0.43
MEP50_HUMAN WDR77 Methylosome protein 50 5.329e-15 0.35
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 7.661e-15 0.35
NK2R_CAVPO TACR2 Substance-K receptor 9.215e-15 0.29
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 9.659e-15 0.47
HRH1_CAVPO HRH1 Histamine H1 receptor 9.77e-15 0.53
GLR_MOUSE Gcgr Glucagon receptor 1.155e-14 0.30
FA10_RABIT F10 Coagulation factor X 1.643e-14 0.44
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 1.821e-14 0.52
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 1.854e-14 0.55
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.887e-14 0.35
HDAC1_HUMAN HDAC1 Histone deacetylase 1 2.065e-14 0.44
HDAC3_HUMAN HDAC3 Histone deacetylase 3 3.597e-14 0.42
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 3.608e-14 0.35
ACES_ANOGA Ace Acetylcholinesterase 5.518e-14 0.42
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 6.095e-14 0.34
TYTR_TRYBB TPR Trypanothione reductase 7.438e-14 0.37
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 8.293e-14 0.30
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 9.87e-14 0.61
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 9.892e-14 0.46
DRD5_HUMAN DRD5 D(1B) dopamine receptor 1.349e-13 0.34
DPP2_HUMAN DPP7 Dipeptidyl peptidase 2 1.592e-13 0.36
THB_HUMAN THRB Thyroid hormone receptor beta 1.628e-13 0.39
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 1.99e-13 0.43
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 1.99e-13 0.43
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 5.104e-13 0.60
EGFR_HUMAN EGFR Epidermal growth factor receptor 5.621e-13 0.43
CSF1R_MOUSE Csf1r Macrophage colony-stimulating factor 1 receptor 6.057e-13 0.34
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 6.406e-13 0.46
CAC1H_HUMAN CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H 7.867e-13 0.40
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 1.098e-12 0.35
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.118e-12 0.53
EIS_MYCTU eis N-acetyltransferase Eis 1.341e-12 0.31
S6A12_HUMAN SLC6A12 Sodium- and chloride-dependent betaine transporter 1.761e-12 0.31
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 2.443e-12 0.30
PAOX_HUMAN PAOX Peroxisomal N(1)-acetyl-spermine/spermidine oxidase 3.335e-12 0.36
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 3.563e-12 0.32
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 4.108e-12 0.36
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 4.429e-12 0.31
E3UJZ5_SPOLI Ecdysone receptor 6.353e-12 0.33
ECR_BOMMO EcR Ecdysone receptor 6.613e-12 0.33
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 8.653e-12 0.37
PRIO_SHEEP PRNP Major prion protein 9.379e-12 0.29
HRH3_RAT Hrh3 Histamine H3 receptor 9.753e-12 0.44
HSP12_CAEEL hsp-16.2 Heat shock protein Hsp-16.2 1.009e-11 0.34
DUS3_HUMAN DUSP3 Dual specificity protein phosphatase 3 1.234e-11 0.44
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 1.266e-11 0.39
NK2R_MESAU TACR2 Substance-K receptor 1.976e-11 0.34
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 2.015e-11 0.45
UR2R_HUMAN UTS2R Urotensin-2 receptor 2.092e-11 0.40
RENI_CALJA REN Renin 2.238e-11 0.32
GLUC_HUMAN GCG Glucagon 2.46e-11 0.37
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 2.722e-11 0.42
LPXC_PSEAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 3.15e-11 0.37
Q9V396_DROME CAH1 Carbonic anhydrase 1 3.301e-11 0.46
Q9VTU8_DROME CAH2 Carbonic anhydrase 2, isoform A 3.301e-11 0.46
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 4.848e-11 0.34
Q9FD53_STREE mvaD Diphosphomevalonate decarboxylase 6.135e-11 0.29
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 6.627e-11 0.34
A5H660_SCHMA HDAC8 Histone deacetylase 8 8.306e-11 0.32
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 9.418e-11 0.36
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.009e-10 0.38
EST1_RABIT Liver carboxylesterase 1 1.148e-10 0.35
Q3Y5H1_9GAMC 3C-like protease 1.17e-10 0.32
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 1.402e-10 0.35
PA_I34A1 PA Polymerase acidic protein 1.443e-10 0.31
CALM_BOVIN CALM Calmodulin 1.577e-10 0.28
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 1.647e-10 0.28
US28_HCMVA US28 G-protein coupled receptor homolog US28 1.647e-10 0.28
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.936e-10 0.30
CASR_RAT Casr Extracellular calcium-sensing receptor 1.939e-10 0.33
DRD1_HUMAN DRD1 D(1A) dopamine receptor 2.014e-10 0.36
CNR2_RAT Cnr2 Cannabinoid receptor 2 2.111e-10 0.34
CATK_RABIT CTSK Cathepsin K 2.134e-10 0.35
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 2.233e-10 0.43
CATS_MOUSE Ctss Cathepsin S 2.289e-10 0.35
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 3.333e-10 0.54
ELOV6_MOUSE Elovl6 Elongation of very long chain fatty acids protein 6 3.34e-10 0.30
SC6A9_RAT Slc6a9 Sodium- and chloride-dependent glycine transporter 1 3.497e-10 0.33
KMT5A_HUMAN KMT5A N-lysine methyltransferase KMT5A 3.764e-10 0.39
HDAC2_HUMAN HDAC2 Histone deacetylase 2 4.021e-10 0.37
HKDC1_HUMAN HKDC1 Hexokinase HKDC1 4.402e-10 0.33
HRH1_HUMAN HRH1 Histamine H1 receptor 4.417e-10 0.39
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 4.825e-10 0.34
TRPV4_MOUSE Trpv4 Transient receptor potential cation channel subfamily V member 4 4.884e-10 0.29
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 5.337e-10 0.36
CHLE_HUMAN BCHE Cholinesterase 5.363e-10 0.50
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 5.416e-10 0.34
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 6.225e-10 0.34
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 7.029e-10 0.43
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 7.059e-10 0.46
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 7.633e-10 0.37
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 7.733e-10 0.46
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.131e-09 0.43
DRD2_MOUSE Drd2 D(2) dopamine receptor 1.167e-09 0.35
DRD3_CHLAE DRD3 D(3) dopamine receptor 1.199e-09 0.34
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 1.283e-09 0.36
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.334e-09 0.46
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 1.482e-09 0.36
ACES_HUMAN ACHE Acetylcholinesterase 1.512e-09 0.39
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.63e-09 0.36
Q9WJQ2_9HIV1 reverse transcriptase Reverse transcriptase protein 2.02e-09 0.48
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 2.044e-09 0.33
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 2.117e-09 0.35
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 2.42e-09 0.35
LSS_HUMAN LSS Lanosterol synthase 2.58e-09 0.33
HDAC4_HUMAN HDAC4 Histone deacetylase 4 2.793e-09 0.40
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 3.447e-09 0.37
PTN5_HUMAN PTPN5 Tyrosine-protein phosphatase non-receptor type 5 3.517e-09 0.44
O97467_PLAFA ht1 Hexose transporter 1 3.578e-09 0.46
Q6L5J4_HUMAN FPRL2 FML2_HUMAN 4.306e-09 0.39
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 4.389e-09 0.39
CATS_HUMAN CTSS Cathepsin S 4.416e-09 0.35
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 4.923e-09 0.30
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 4.923e-09 0.30
CCKAR_RAT Cckar Cholecystokinin receptor type A 5.177e-09 0.38
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 5.221e-09 0.33
DPO3_BACSU polC DNA polymerase III PolC-type 5.485e-09 0.32
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 5.945e-09 0.30
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 6.254e-09 0.39
PI2R_HUMAN PTGIR Prostacyclin receptor 6.366e-09 0.46
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 6.738e-09 0.32
MDM2_HUMAN MDM2 E3 ubiquitin-protein ligase Mdm2 7.911e-09 0.42
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 8.524e-09 0.43
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 8.632e-09 0.33
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 9.097e-09 0.36
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 1.024e-08 0.48
ALF_MYCTU fba Fructose-bisphosphate aldolase 1.05e-08 0.37
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.059e-08 0.59
LIPS_HUMAN LIPE Hormone-sensitive lipase 1.122e-08 0.42
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.123e-08 0.66
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 1.322e-08 0.29
UR2R_RAT Uts2r Urotensin-2 receptor 1.388e-08 0.36
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 1.51e-08 0.37
DPOL_HCMVA UL54 DNA polymerase catalytic subunit 1.559e-08 0.41
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 1.589e-08 0.30
NDKB_HUMAN NME2 Nucleoside diphosphate kinase B 1.634e-08 0.28
GP183_HUMAN GPR183 G-protein coupled receptor 183 1.722e-08 0.35
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.881e-08 0.33
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 1.911e-08 0.51
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 2.066e-08 0.34
O61059_LEIME LmGT2 Glucose transporter 2.166e-08 0.46
Q8IL32_PLAF7 Heat shock protein 90, putative 2.368e-08 0.37
MK10_RAT Mapk10 Mitogen-activated protein kinase 10 2.513e-08 0.43
DRD1_RAT Drd1 D(1A) dopamine receptor 2.531e-08 0.39
CAH9_HUMAN CA9 Carbonic anhydrase 9 2.829e-08 0.59
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 3.667e-08 0.46
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 3.714e-08 0.41
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 4.901e-08 0.34
DPOL_HHV6U U38 DNA polymerase catalytic subunit 5.363e-08 0.28
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 5.667e-08 0.34
WNT3A_HUMAN WNT3A Protein Wnt-3a 5.668e-08 0.35
SHH_MOUSE Shh Sonic hedgehog protein 6.424e-08 0.39
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 7.031e-08 0.43
BAD_HUMAN BAD Bcl2-associated agonist of cell death 7.998e-08 0.33
MMP13_BOVIN MMP13 Collagenase 3 8.917e-08 0.44
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 9.155e-08 0.50
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 9.211e-08 0.60
MAG_MOUSE Mag Myelin-associated glycoprotein 9.328e-08 0.29
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 9.412e-08 0.30
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 1.034e-07 0.42
NCOA3_HUMAN NCOA3 Nuclear receptor coactivator 3 1.124e-07 0.45
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 1.172e-07 0.34
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.198e-07 0.50
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 1.23e-07 0.29
SC6A9_HUMAN SLC6A9 Sodium- and chloride-dependent glycine transporter 1 1.237e-07 0.37
DRD2_BOVIN DRD2 D(2) dopamine receptor 1.251e-07 0.53
AURKB_HUMAN AURKB Aurora kinase B 1.261e-07 0.53
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 1.365e-07 0.28
HRH1_RAT Hrh1 Histamine H1 receptor 1.605e-07 0.40
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.633e-07 0.42
Q76353_9HIV1 Integrase 1.649e-07 0.39
MITF_HUMAN MITF Microphthalmia-associated transcription factor 1.883e-07 0.35
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 2.446e-07 0.39
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 2.81e-07 0.45
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 2.981e-07 0.40
AURKA_HUMAN AURKA Aurora kinase A 2.993e-07 0.53
PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 3.527e-07 0.44
HDAC5_HUMAN HDAC5 Histone deacetylase 5 3.561e-07 0.34
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 4.38e-07 0.35
LMBL3_HUMAN L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 4.999e-07 0.39
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 5.15e-07 0.30
LMBL1_HUMAN L3MBTL1 Lethal(3)malignant brain tumor-like protein 1 5.386e-07 0.39
GALR3_HUMAN GALR3 Galanin receptor type 3 5.413e-07 0.36
MMP3_HUMAN MMP3 Stromelysin-1 6.823e-07 0.38
EST2_HUMAN CES2 Cocaine esterase 7.021e-07 0.35
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 7.213e-07 0.34
RCE1_YEAST RCE1 CAAX prenyl protease 2 8.149e-07 0.35
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 8.987e-07 0.39
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 9.394e-07 0.37
NK2R_MOUSE Tacr2 Substance-K receptor 9.875e-07 0.33
SKN1_CAEEL skn-1 Protein skinhead-1 9.881e-07 0.45
MMP2_HUMAN MMP2 72 kDa type IV collagenase 9.914e-07 0.36
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 9.956e-07 0.30
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 1.202e-06 0.32
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 1.231e-06 0.32
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.285e-06 0.30
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 1.418e-06 0.30
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 1.432e-06 0.32
CXCR3_RAT Cxcr3 C-X-C chemokine receptor type 3 1.537e-06 0.29
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 1.643e-06 0.34
CCR9_HUMAN CCR9 C-C chemokine receptor type 9 1.74e-06 0.32
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.82e-06 0.44
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 1.858e-06 0.28
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 2.128e-06 0.31
IKKB_HUMAN IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 2.194e-06 0.40
KMO_HUMAN KMO Kynurenine 3-monooxygenase 2.236e-06 0.33
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 2.362e-06 0.48
LCK_HUMAN LCK Tyrosine-protein kinase Lck 2.555e-06 0.38
Q8MWR1_SPOFR USP Ultraspiracle protein 2.606e-06 0.32
Q8MWR2_SPOFR EcR Ecdysteroid receptor 2.606e-06 0.32
ACES_BOVIN ACHE Acetylcholinesterase 2.622e-06 0.35
WEE1_HUMAN WEE1 Wee1-like protein kinase 2.67e-06 0.31
ACES_ELEEL ache Acetylcholinesterase 2.933e-06 0.42
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 3.33e-06 0.37
DRD2_CHLAE DRD2 D(2) dopamine receptor 3.415e-06 0.34
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 3.451e-06 0.42
DPOL_VACCW POL DNA polymerase 3.469e-06 0.30
USP_DROME usp Protein ultraspiracle 3.596e-06 0.33
HDAC1_RAT Hdac1 Histone deacetylase 1 3.677e-06 0.29
LYAM2_HUMAN SELE E-selectin 3.727e-06 0.46
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 4.113e-06 0.41
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 4.163e-06 0.48
HS90B_HUMAN HSP90AB1 Heat shock protein HSP 90-beta 4.393e-06 0.38
KLF5_HUMAN KLF5 Krueppel-like factor 5 4.574e-06 0.34
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 4.626e-06 0.34
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 4.823e-06 0.30
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 5.435e-06 0.32
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 5.907e-06 0.30
DPO3A_BACSU dnaE DNA polymerase III subunit alpha 5.988e-06 0.30
PCNA_HUMAN PCNA Proliferating cell nuclear antigen 5.988e-06 0.30
PLEC_HUMAN PLEC Plectin 6.291e-06 0.30
ANM3_HUMAN PRMT3 Protein arginine N-methyltransferase 3 6.564e-06 0.35
TNFA_HUMAN TNF Tumor necrosis factor 6.613e-06 0.40
HRH2_HUMAN HRH2 Histamine H2 receptor 6.691e-06 0.34
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 6.749e-06 0.36
5HT1D_PIG HTR1D 5-hydroxytryptamine receptor 1D 7.205e-06 0.40
HDA11_HUMAN HDAC11 Histone deacetylase 11 7.501e-06 0.34
LUCI_AQULA Luciferin 4-monooxygenase 7.953e-06 0.28
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 7.978e-06 0.51
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 8.066e-06 0.53
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 8.868e-06 0.47
TXK_HUMAN TXK Tyrosine-protein kinase TXK 9.74e-06 0.30

Dezocine

OPRM_HUMAN OPRM1 Mu-type opioid receptor 3.644e-26 1.00
F7HEV7_MACMU YTHDF2 G_PROTEIN_RECEP_F1_2 domain-containing protein 3.014e-91 0.43
H9FL65_MACMU OPRK1 Kappa-type opioid receptor 3.014e-91 0.43
OPRM_MACMU OPRM1 Mu-type opioid receptor 4.443e-81 0.43
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 2.422e-71 0.46
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 3.354e-49 0.46
OPRM_BOVIN OPRM1 Mu-type opioid receptor 3.501e-39 0.41
OPRM_CAVPO OPRM1 Mu-type opioid receptor 2.29e-37 0.49
OPRM_RAT Oprm1 Mu-type opioid receptor 5.047e-36 0.49
ZN664_CAVPO ZNF664 Zinc finger protein 664 1.78e-34 0.43
OPRD_HUMAN OPRD1 Delta-type opioid receptor 1.918e-34 0.63
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 6.922e-25 0.43
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 2.059e-24 0.63
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 5.151e-24 0.49
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 2.562e-22 0.43
SECA1_STAA8 secA1 Protein translocase subunit SecA 1 1.708e-20 0.33
OPRM_MOUSE Oprm1 Mu-type opioid receptor 3.171e-20 0.43
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 3.488e-18 0.29
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 7.772e-16 0.39
SHBG_HUMAN SHBG Sex hormone-binding globulin 3.997e-15 0.34
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 6.994e-15 0.43
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 4.763e-14 0.31
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 1.125e-13 0.42
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 2.008e-13 0.29
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 6.947e-13 0.42
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 7.838e-12 0.29
ERG2_YEAST ERG2 C-8 sterol isomerase 5.033e-11 0.43
OPRD_MOUSE Oprd1 Delta-type opioid receptor 2.012e-10 0.43
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.986e-09 0.43
ESR1_MOUSE Esr1 Estrogen receptor 3.055e-09 0.29
ESR2_MOUSE Esr2 Estrogen receptor beta 3.055e-09 0.29
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 1.835e-07 0.32
Q690N0_BOVIN PGR Progesterone receptor 2.145e-07 0.31
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 3.852e-07 0.47
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.558e-06 0.29
OPRD_RAT Oprd1 Delta-type opioid receptor 2.671e-06 0.42

Brinzolamide

MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 6.44e-24 1.00
Q5TU56_ANOGA 1272966 Carbonic anhydrase 2.999e-22 1.00
CAN_YEAST NCE103 Carbonic anhydrase 2.718e-21 1.00
C0IX24_STYPI CA2 Carbonic anhydrase 1.959e-20 1.00
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 1.959e-20 1.00
B2V8E3_SULSY Carbonate dehydratase 1.163e-19 1.00
B5SU02_STYPI CA Alpha carbonic anhydrase 1.163e-19 1.00
Q31FD6_HYDCU Carbonic anhydrase, alpha family 1.163e-19 1.00
A6YCJ1_9METZ Astrosclerin-3 1.246e-18 1.00
CYNT_HELPY cynT Carbonic anhydrase 1.11e-16 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.168e-13 1.00
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 4.984e-13 1.00
CAH13_MOUSE Ca13 Carbonic anhydrase 13 4.181e-12 1.00
CAH15_MOUSE Ca15 Carbonic anhydrase 15 6.71e-12 1.00
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 2.471e-11 1.00
Q6FTL6_CANGA NCE103 Carbonic anhydrase 2.471e-11 1.00
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 4.128e-10 1.00
CAH4_HUMAN CA4 Carbonic anhydrase 4 5.542e-10 1.00
CAN_CANAL NCE103 Carbonic anhydrase 3.372e-08 1.00
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.579e-06 1.00
CAH13_HUMAN CA13 Carbonic anhydrase 13 1.743e-06 1.00
CAH6_HUMAN CA6 Carbonic anhydrase 6 2.548e-06 1.00
CAH4_BOVIN CA4 Carbonic anhydrase 4 3.812e-06 1.00
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.483e-05 1.00
CAH14_HUMAN CA14 Carbonic anhydrase 14 0.002049 1.00
CAH7_HUMAN CA7 Carbonic anhydrase 7 0.006951 1.00
CAH1_HUMAN CA1 Carbonic anhydrase 1 0.02958 1.00
CAH12_HUMAN CA12 Carbonic anhydrase 12 0.5726 1.00
CAH9_HUMAN CA9 Carbonic anhydrase 9 0.6108 1.00
CAH_METTE Carbonic anhydrase 1.7e-10 0.54

Anastrozole

CP19A_HUMAN CYP19A1 Aromatase 9.518e-24 1.00
A1XG20_PENDI cyp51 Cytochrome P450 14alpha-demethylase 3.27e-82 0.33
PDE4D_RAT Pde4d cAMP-specific 3',5'-cyclic phosphodiesterase 4D 7.545e-40 0.32
Q96W81_ASPFM cyp51B 14-alpha sterol demethylase 2.975e-32 0.33
CP121_MYCTU cyp121 Mycocyclosin synthase 5.245e-27 0.33
CP51A_ASPFU cyp51A 14-alpha sterol demethylase Cyp51A 1.039e-18 0.30
CP51_CANAL ERG11 Lanosterol 14-alpha demethylase 1.039e-18 0.30
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 1.441e-10 0.33
STS_HUMAN STS Steryl-sulfatase 4.813e-10 0.53

Cyclizine

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 5.433e-22 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 2.283e-11 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.564e-11 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 8.317e-11 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 3.882e-10 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 9.825e-10 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 4.108e-08 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 7.158e-08 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 8.476e-08 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.583e-07 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.401e-06 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 4.641e-06 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.0001672 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.0002304 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.0004394 1.00
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 1.812e-118 0.61
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 1.437e-95 0.61
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 2.641e-91 0.43
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 2.641e-91 0.43
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 1.271e-82 0.43
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 2.151e-66 0.61
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 7.955e-55 0.44
OPRX_HUMAN OPRL1 Nociceptin receptor 1.507e-52 0.53
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 8.161e-51 0.44
TYRP1_MOUSE Tyrp1 5,6-dihydroxyindole-2-carboxylic acid oxidase 1.654e-40 0.34
OPRD_HUMAN OPRD1 Delta-type opioid receptor 3.981e-25 0.59
BLAB_BACCE Metallo-beta-lactamase type 2 4.642e-25 0.28
HRH4_HUMAN HRH4 Histamine H4 receptor 6.793e-25 0.35
DRD5_HUMAN DRD5 D(1B) dopamine receptor 4.101e-23 0.39
OPRM_HUMAN OPRM1 Mu-type opioid receptor 6.295e-23 0.53
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.274e-21 0.37
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.314e-21 0.59
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 2.202e-20 0.43
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 4.408e-19 0.32
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.716e-18 0.37
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.991e-18 0.46
5HT3B_HUMAN HTR3B 5-hydroxytryptamine receptor 3B 1.882e-17 0.33
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.11e-16 0.41
MC4R_HUMAN MC4R Melanocortin receptor 4 1.11e-16 0.68
MGLL_MOUSE Mgll Monoglyceride lipase 2.22e-16 0.43
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 6.661e-16 0.40
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 5.662e-15 0.40
PPAP_HUMAN ACP3 Prostatic acid phosphatase 1.754e-14 0.28
HRH1_CAVPO HRH1 Histamine H1 receptor 5.285e-14 0.41
MGLL_RAT Mgll Monoglyceride lipase 2.255e-13 0.43
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 4.756e-13 0.41
CALM_BOVIN CALM Calmodulin 1.167e-12 0.34
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 4.101e-12 0.36
CA2D1_HUMAN CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 4.367e-12 0.43
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 1.638e-11 0.31
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.772e-11 0.40
HRH4_RAT Hrh4 Histamine H4 receptor 1.792e-11 0.33
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 1.003e-10 0.49
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 1.994e-10 0.33
MGLL_HUMAN MGLL Monoglyceride lipase 2.804e-10 0.43
LUXR_ALIFS luxR Transcriptional activator protein LuxR 4.291e-10 0.29
RCE1_YEAST RCE1 CAAX prenyl protease 2 4.894e-10 0.41
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 6.024e-10 0.31
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 8.127e-10 0.37
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.234e-09 0.49
CP19A_RAT Cyp19a1 Aromatase 1.64e-09 0.37
5HT2C_MOUSE Htr2c 5-hydroxytryptamine receptor 2C 1.983e-09 0.32
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 2.239e-09 0.50
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 2.636e-09 0.49
Q8VH27_CAVPO GPM2 Muscarinic acetylcholine receptor 3.402e-09 0.28
O31048_PORGN DPP IV Dipeptidyl peptidase IV 4.869e-09 0.37
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 6.464e-09 0.49
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 8.61e-09 0.39
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 8.683e-09 0.49
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.077e-08 0.40
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 2.145e-08 0.49
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 5.805e-08 0.47
DRD1_RAT Drd1 D(1A) dopamine receptor 5.906e-08 0.35
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 7.691e-08 0.49
CHKA_HUMAN CHKA Choline kinase alpha 7.832e-08 0.35
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 8.058e-08 0.33
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.266e-07 0.28
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 2.077e-07 0.34
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 2.43e-07 0.41
HCN1_HUMAN HCN1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 7.169e-07 0.35
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 1.324e-06 0.28
ACHP_LYMST Acetylcholine-binding protein 1.569e-06 0.38
PRIO_SHEEP PRNP Major prion protein 1.657e-06 0.30
B2LA1_MOUSE Bcl2a1 Bcl-2-related protein A1 2.475e-06 0.30
B2LA1_HUMAN BCL2A1 Bcl-2-related protein A1 3.57e-06 0.29
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 3.933e-06 0.30
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 4.043e-06 0.32
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 4.46e-06 0.32
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 4.778e-06 0.32
MBTD1_HUMAN MBTD1 MBT domain-containing protein 1 5.252e-06 0.28
PTN22_HUMAN PTPN22 Tyrosine-protein phosphatase non-receptor type 22 5.937e-06 0.30
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 6.032e-06 0.36
BLA2_BACCE blm Metallo-beta-lactamase type 2 8.558e-06 0.28
CNR1_HUMAN CNR1 Cannabinoid receptor 1 8.841e-06 0.49

Ketamine

ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 1.377e-17 1.00
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 4.652e-10 1.00
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 5.715e-06 1.00
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 1.778e-05 1.00
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 0.001649 1.00
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 4.431e-13 0.32
HPPD_PIG HPD 4-hydroxyphenylpyruvate dioxygenase 1.732e-08 0.31

Tubocurarine

ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 1.377e-17 1.00
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.22e-15 1.00
A9XFY4_MUSDO nAChRalpha5 Nicotinic acetylcholine receptor alpha 5 subunit 3.375e-10 1.00
KCNN3_RAT Kcnn3 Small conductance calcium-activated potassium channel protein 3 1.656e-08 1.00
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 1.529e-05 1.00
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 0.0001329 1.00
ACHA3_HUMAN CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 0.0002675 1.00
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 0.000403 1.00
ACHB2_RAT Chrnb2 Neuronal acetylcholine receptor subunit beta-2 0.1713 1.00
ACHA4_RAT Chrna4 Neuronal acetylcholine receptor subunit alpha-4 0.1901 1.00
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 0.2631 1.00
ACHA2_HUMAN CHRNA2 Neuronal acetylcholine receptor subunit alpha-2 2.697e-49 0.81
DRD1_MOUSE Drd1 D(1A) dopamine receptor 2.087e-41 0.35
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.444e-28 0.35
DRD1_RAT Drd1 D(1A) dopamine receptor 1.92e-26 0.41
DRD2_RAT Drd2 D(2) dopamine receptor 1.522e-12 0.62
DRD5_HUMAN DRD5 D(1B) dopamine receptor 1.577e-09 0.33
PDE1A_HUMAN PDE1A Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 1.969e-09 0.52
TF_HUMAN F3 Tissue factor 4.27e-07 0.33
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 5.437e-07 0.88

Ergometrine

5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 1.455e-17 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 2.693e-12 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 2.909e-12 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 1.615e-09 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 4.114e-09 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 7.82e-07 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 1.176e-05 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 0.0001137 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.0005663 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.0008632 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.002356 1.00
CXCR3_MOUSE Cxcr3 C-X-C chemokine receptor type 3 4.77e-107 0.54
CXCR3_RAT Cxcr3 C-X-C chemokine receptor type 3 3.119e-86 0.49
DRD1_MOUSE Drd1 D(1A) dopamine receptor 1.227e-32 0.63
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 1.037e-29 0.54
GRP1_RAT Rasgrp1 RAS guanyl-releasing protein 1 1.069e-19 0.38
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 3.114e-17 0.63
CGAS_HUMAN CGAS Cyclic GMP-AMP synthase 2.442e-15 0.29
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.754e-14 0.86
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 3.741e-14 0.69
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 5.123e-12 0.69
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 7.968e-12 0.58
SSR2_RAT Sstr2 Somatostatin receptor type 2 2.727e-09 0.34
SSR1_RAT Sstr1 Somatostatin receptor type 1 8.093e-08 0.34
DRD5_HUMAN DRD5 D(1B) dopamine receptor 2.447e-07 0.63
PLEC_HUMAN PLEC Plectin 5.448e-07 0.70
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 7.738e-07 0.58
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 5.144e-06 0.58

Bromocriptine

5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 5.551e-16 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 8.882e-15 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 3.82e-11 1.00
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 2.504e-10 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 2.652e-10 1.00
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.016e-09 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 2.146e-08 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 6.184e-08 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.586e-07 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 2.504e-06 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.0002019 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.0003157 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.0003399 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 0.001285 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.003276 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.003775 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.008326 1.00
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 0.009656 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 0.009899 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.01462 1.00
ANDR_RAT Ar Androgen receptor 0.01773 1.00
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 0.1323 1.00
DRD2_RAT Drd2 D(2) dopamine receptor 0.8669 1.00
CXCR3_MOUSE Cxcr3 C-X-C chemokine receptor type 3 2.061e-51 0.31
CXCR3_RAT Cxcr3 C-X-C chemokine receptor type 3 3.594e-42 0.30
DRD1_MOUSE Drd1 D(1A) dopamine receptor 1.377e-17 0.33
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 1.632e-14 0.33
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 1.215e-10 0.47
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 2.136e-09 0.33
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 7.924e-08 0.47
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 6.742e-07 0.42
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 7.904e-07 0.41
SSR1_RAT Sstr1 Somatostatin receptor type 1 5.698e-06 0.29

Dexfenfluramine

SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 9.992e-16 1.00
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 9.299e-05 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 0.758 1.00
KIFC1_HUMAN KIFC1 Kinesin-like protein KIFC1 3.549e-60 0.35
PDS_SYNE7 pds 15-cis-phytoene desaturase 7.793e-57 0.37
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 5.149e-48 0.36
GPR52_HUMAN GPR52 G-protein coupled receptor 52 1.934e-43 0.32
UBC12_HUMAN UBE2M NEDD8-conjugating enzyme Ubc12 1.204e-42 0.34
TERT_RAT Tert Telomerase reverse transcriptase 7.142e-37 0.29
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 4.586e-28 0.39
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 5.664e-24 0.34
DEF_STAAM def Peptide deformylase 6.335e-24 0.42
RXFP1_HUMAN RXFP1 Relaxin receptor 1 4.162e-19 0.33
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 1.508e-17 0.32
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 3.06e-17 0.32
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 1.221e-15 0.29
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 7.438e-15 0.31
ACOD1_MOUSE Scd1 Acyl-CoA desaturase 1 8.993e-15 0.32
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 1.532e-14 0.36
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 8.045e-13 0.32
DGAT1_RAT Dgat1 Diacylglycerol O-acyltransferase 1 2.95e-12 0.29
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 1.014e-11 0.31
ACOD1_RAT Scd1 Acyl-CoA desaturase 1 1.823e-11 0.33
Q6DMN0_TOXGO CPL Cathepsin L 3.551e-11 0.33
CETP_RABIT CETP Cholesteryl ester transfer protein 3.614e-11 0.39
ACOD_HUMAN SCD Acyl-CoA desaturase 4.852e-11 0.31
PSBA_MARPO psbA Photosystem II protein D1 8.923e-11 0.34
CATD_HUMAN CTSD Cathepsin D 2.306e-10 0.33
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 2.718e-10 0.32
AHR_RABIT AHR Aryl hydrocarbon receptor 7.255e-10 0.30
LUXS_ALIF1 luxR Transcriptional activator protein LuxR 9.172e-10 0.35
AOFB_RAT Maob Amine oxidase [flavin-containing] B 9.906e-10 0.38
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.706e-09 0.36
NK1R_HUMAN TACR1 Substance-P receptor 1.779e-09 0.34
CCL2_HUMAN CCL2 C-C motif chemokine 2 2.389e-09 0.30
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 3.285e-09 0.33
BACE2_HUMAN BACE2 Beta-secretase 2 4.885e-09 0.33
O61059_LEIME LmGT2 Glucose transporter 6.387e-09 0.34
CATB_BOVIN CTSB Cathepsin B 1.424e-08 0.31
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 1.79e-08 0.32
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 2.311e-08 0.38
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 3.988e-08 0.37
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 5.106e-08 0.36
TRPV3_HUMAN TRPV3 Transient receptor potential cation channel subfamily V member 3 9.734e-08 0.35
OXDA_MOUSE Dao D-amino-acid oxidase 9.926e-08 0.38
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 1.496e-07 0.34
IDE_HUMAN IDE Insulin-degrading enzyme 1.505e-07 0.40
O97467_PLAFA ht1 Hexose transporter 1 1.8e-07 0.34
RGS4_HUMAN RGS4 Regulator of G-protein signaling 4 2.317e-07 0.31
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 4.168e-07 0.35
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 5.326e-07 0.37
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 5.343e-07 0.38
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 6.918e-07 0.32
Q8MTZ4_9TRYP PPase1 Vacuolar-type proton translocating pyrophosphatase 1 9.396e-07 0.29
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 1.042e-06 0.28
PTN9_HUMAN PTPN9 Tyrosine-protein phosphatase non-receptor type 9 1.166e-06 0.28
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 1.173e-06 0.37
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.213e-06 0.46
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 1.628e-06 0.37
PETD_SPIOL petD Cytochrome b6-f complex subunit 4 2.122e-06 0.30
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 2.528e-06 0.32
CAN1_RAT Capn1 Calpain-1 catalytic subunit 6.558e-06 0.29
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 6.639e-06 0.30
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 6.644e-06 0.35
OXDA_HUMAN DAO D-amino-acid oxidase 6.951e-06 0.38
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 9.714e-06 0.31

Dantrolene

CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 8.105e-15 1.00
FTSZ_BACSU ftsZ Cell division protein FtsZ 5.459e-39 0.31
FA5_HUMAN F5 Coagulation factor V 7.748e-24 0.36
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 1.196e-11 0.28
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 3.127e-11 0.38
MEP2_YEAST MEP2 Ammonium transporter MEP2 5.325e-11 0.32
MBD2_HUMAN MBD2 Methyl-CpG-binding domain protein 2 1.105e-10 0.29
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 4.413e-09 0.35
TNNC1_HUMAN TNNC1 Troponin C, slow skeletal and cardiac muscles 9.538e-09 0.49
TNNI3_HUMAN TNNI3 Troponin I, cardiac muscle 9.538e-09 0.49
TNNT2_HUMAN TNNT2 Troponin T, cardiac muscle 9.538e-09 0.49
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 1.255e-08 0.39
Q548M1_ECOLX groL 60 kDa chaperonin 1.284e-08 0.40
Q7BGE6_ECOLX groES 10 kDa chaperonin 1.284e-08 0.40
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 2.415e-07 0.38
PLPL6_MOUSE Pnpla6 Neuropathy target esterase 2.921e-07 0.31
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 2.924e-07 0.38
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 5.969e-07 0.52
NR4A1_HUMAN NR4A1 Nuclear receptor subfamily 4 group A member 1 2.073e-06 0.39

Alimemazine

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 2.207e-12 1.00
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 7.115e-05 1.00
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 6.177e-130 0.74
PRIO_MOUSE Prnp Major prion protein 5.165e-56 0.45
TYTR_TRYCR TPR Trypanothione reductase 1.69e-31 0.45
CALM_BOVIN CALM Calmodulin 3.555e-27 0.45
LYSC1_RAT Lyz1 Lysozyme C-1 1.246e-25 0.32
ITAM_HUMAN ITGAM Integrin alpha-M 1.839e-23 0.29
CHLE_HUMAN BCHE Cholinesterase 4.777e-23 0.61
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 2.362e-22 0.45
CALM1_HUMAN CALM1 Calmodulin-1 2.12e-20 0.45
BGLR_RAT Gusb Beta-glucuronidase 7.563e-20 0.32
EBPL_HUMAN EBPL Emopamil-binding protein-like 7.563e-20 0.32
NOX1_HUMAN NOX1 NADPH oxidase 1 2.667e-17 0.38
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 3.148e-12 0.33
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 2.884e-11 0.36
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.299e-10 0.67
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 4.838e-09 0.32
HRH2_HUMAN HRH2 Histamine H2 receptor 5.049e-09 0.67
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 2.947e-08 0.45
PRIO_HUMAN PRNP Major prion protein 4.166e-08 0.67
DEF_STAAM def Peptide deformylase 6.747e-08 0.32
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 7.695e-07 0.67
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.175e-06 0.45
HRH1_HUMAN HRH1 Histamine H1 receptor 5.463e-06 0.67
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 7.871e-06 0.30

Levodopa

LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 5.698e-12 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 1.81e-08 1.00
LCK_HUMAN LCK Tyrosine-protein kinase Lck 0.006735 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 0.01748 1.00
TPH1_HUMAN TPH1 Tryptophan 5-hydroxylase 1 8.04e-137 0.39
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 5.671e-117 0.58
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 1.314e-116 0.47
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 9.868e-107 0.65
TY3H_RAT Th Tyrosine 3-monooxygenase 1.29e-90 0.73
IBP5_HUMAN IGFBP5 Insulin-like growth factor-binding protein 5 3.574e-73 0.41
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 4.928e-68 0.50
TPH1_RAT Tph1 Tryptophan 5-hydroxylase 1 9.923e-68 0.33
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 7.59e-63 0.44
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 7.59e-63 0.44
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 2.057e-62 0.44
KYNU_HUMAN KYNU Kynureninase 5.21e-60 0.38
TPH2_HUMAN TPH2 Tryptophan 5-hydroxylase 2 7.996e-58 0.29
MURI_LACFE murI Glutamate racemase 1.061e-56 0.45
GRIA2_RAT Gria2 Glutamate receptor 2 1.74e-56 0.55
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 1.742e-55 0.31
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 7.599e-54 0.37
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 1.271e-51 0.39
B9V8S1_XENLA grik2.L Ionotropic glutamate receptor subunit GluR6(Q) 1.302e-51 0.33
MGRA_STAAU mgrA HTH-type transcriptional regulator MgrA 7.227e-49 0.39
TYTR_CRIFA TPR Trypanothione reductase 1.481e-48 0.39
OPRM_RAT Oprm1 Mu-type opioid receptor 2.675e-48 0.49
KYNU_RAT Kynu Kynureninase 6.888e-48 0.38
GRIA3_RAT Gria3 Glutamate receptor 3 6.68e-45 0.42
DDC_MOUSE Ddc Aromatic-L-amino-acid decarboxylase 8.414e-45 0.36
AAA1_RAT Slc7a10 Asc-type amino acid transporter 1 1.148e-44 0.35
MMP2_RAT Mmp2 72 kDa type IV collagenase 1.148e-44 0.35
TY3H_HUMAN TH Tyrosine 3-monooxygenase 1.317e-44 0.73
GRIK5_HUMAN GRIK5 Glutamate receptor ionotropic, kainate 5 2.238e-44 0.33
ADA2A_MOUSE Adra2a Alpha-2A adrenergic receptor 3.092e-44 0.35
ADA2C_MOUSE Adra2c Alpha-2C adrenergic receptor 3.092e-44 0.35
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 2.727e-43 0.36
CBPA1_BOVIN CPA1 Carboxypeptidase A1 4.021e-43 0.36
GRIA3_HUMAN GRIA3 Glutamate receptor 3 6.921e-42 0.33
OPRD_RAT Oprd1 Delta-type opioid receptor 2.95e-41 0.49
NK1R_RAT Tacr1 Substance-P receptor 1.12e-40 0.43
SO1C1_MOUSE Slco1c1 Solute carrier organic anion transporter family member 1C1 4.449e-40 0.50
GRIA1_MOUSE Gria1 Glutamate receptor 1 5.001e-40 0.33
GLT_PYRHO Glutamate transporter homolog 4.474e-39 0.31
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 7.151e-39 0.44
ARGI2_HUMAN ARG2 Arginase-2, mitochondrial 6.694e-38 0.30
VM1B1_BOTAS Snake venom metalloproteinase BaP1 7.854e-38 0.33
DHAS_HELPY asd Aspartate-semialdehyde dehydrogenase 1.443e-37 0.30
GRM8_MOUSE Grm8 Metabotropic glutamate receptor 8 1.443e-37 0.30
GRIA1_HUMAN GRIA1 Glutamate receptor 1 4.166e-37 0.37
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 5.651e-37 0.37
GRIK2_HUMAN GRIK2 Glutamate receptor ionotropic, kainate 2 1.317e-36 0.33
ARP19_RAT Arpp19 cAMP-regulated phosphoprotein 19 1.634e-36 0.45
HISX_ECOLI hisD Histidinol dehydrogenase 3.142e-36 0.30
GRIA4_RAT Gria4 Glutamate receptor 4 8.966e-36 0.33
CSK_HUMAN CSK Tyrosine-protein kinase CSK 4.954e-35 0.46
AMPB_RAT Rnpep Aminopeptidase B 5.225e-35 0.33
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 5.971e-35 0.30
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 1.001e-34 0.36
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 1.256e-34 0.36
AMPL_PIG LAP3 Cytosol aminopeptidase 2.04e-34 0.31
A5A4K8_RABIT MLNR Motilin receptor 5.891e-34 0.42
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.455e-33 0.36
Q39829_SOYBN Lipoxygenase 8.209e-33 0.53
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 1.025e-32 0.35
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 4.909e-32 0.53
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.427e-31 0.41
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 4.891e-31 0.31
HISX_BRAOC HDH Histidinol dehydrogenase, chloroplastic 1.722e-28 0.29
AMPL_HUMAN LAP3 Cytosol aminopeptidase 1.953e-28 0.31
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 1.68e-27 0.53
GRIK5_RAT Grik5 Glutamate receptor ionotropic, kainate 5 2.21e-27 0.31
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 3.47e-27 0.37
GRIA1_RAT Gria1 Glutamate receptor 1 4.843e-27 0.42
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 6.161e-27 0.30
SO4C1_HUMAN SLCO4C1 Solute carrier organic anion transporter family member 4C1 7.892e-27 0.43
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 1.138e-26 0.43
OPRK_RAT Oprk1 Kappa-type opioid receptor 2.673e-26 0.38
Q7ZJM1_9HIV1 pol Integrase 3.227e-26 0.50
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.972e-25 0.41
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 3.612e-25 0.32
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 1.216e-24 0.34
MYOC_HUMAN MYOC Myocilin 1.418e-24 0.30
ARGI1_HUMAN ARG1 Arginase-1 2.158e-24 0.30
ARGI1_RAT Arg1 Arginase-1 2.158e-24 0.30
AMPB_HUMAN RNPEP Aminopeptidase B 4.149e-24 0.35
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 6.789e-24 0.40
PCNA_HUMAN PCNA Proliferating cell nuclear antigen 1.604e-23 0.50
CAN_CANAL NCE103 Carbonic anhydrase 4.752e-23 0.37
GRM8_HUMAN GRM8 Metabotropic glutamate receptor 8 7.974e-23 0.34
GRM6_RAT Grm6 Metabotropic glutamate receptor 6 4.738e-22 0.30
AMPN_PIG ANPEP Aminopeptidase N 5.157e-20 0.40
GFPT1_HUMAN GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 7.563e-20 0.32
GRIK3_HUMAN GRIK3 Glutamate receptor ionotropic, kainate 3 9.687e-20 0.33
GSTM1_HUMAN GSTM1 Glutathione S-transferase Mu 1 1.608e-19 0.31
VGLU3_RAT Slc17a8 Vesicular glutamate transporter 3 3.122e-19 0.31
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3.333e-19 0.31
AA2BR_RAT Adora2b Adenosine receptor A2b 5.678e-19 0.45
GRIA4_HUMAN GRIA4 Glutamate receptor 4 8.083e-19 0.33
NEP_MOUSE Mme Neprilysin 1.092e-18 0.41
GRM8_RAT Grm8 Metabotropic glutamate receptor 8 1.212e-18 0.30
PA_I000X PA Polymerase acidic protein 1.722e-18 0.35
LY96_HUMAN LY96 Lymphocyte antigen 96 8.756e-18 0.34
CBPA1_HUMAN CPA1 Carboxypeptidase A1 1.158e-17 0.31
HISX_BRUSU hisD Histidinol dehydrogenase 2.771e-17 0.30
SEPR_HUMAN FAP Prolyl endopeptidase FAP 4.096e-17 0.31
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 4.231e-17 0.32
GRIA2_HUMAN GRIA2 Glutamate receptor 2 1.11e-16 0.42
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 1.11e-16 0.30
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 1.11e-16 0.45
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 1.11e-16 0.33
DYN1_HUMAN DNM1 Dynamin-1 2.22e-16 0.30
AMPN_HUMAN ANPEP Aminopeptidase N 4.441e-16 0.35
TYRO_MOUSE Tyr Tyrosinase 1.998e-15 0.38
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 3.442e-15 0.33
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 4.33e-15 0.47
BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 4.774e-15 0.33
THB_RAT Thrb Thyroid hormone receptor beta 9.326e-15 0.50
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.332e-14 0.33
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 1.399e-14 0.34
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 1.588e-14 0.35
Q2PCB5_DICLA ca Carbonic anhydrase 1.998e-14 0.39
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 7.683e-14 0.35
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 7.883e-14 0.35
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 1.636e-13 0.37
NOS2_RAT Nos2 Nitric oxide synthase, inducible 1.965e-13 0.29
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 3.235e-13 0.32
IBP3_HUMAN IGFBP3 Insulin-like growth factor-binding protein 3 3.568e-13 0.41
KMO_MOUSE Kmo Kynurenine 3-monooxygenase 5.104e-13 0.32
GLN1B_ECOLI glnA Glutamine synthetase 5.641e-13 0.28
NANA_STREE nanA Sialidase A 1.38e-12 0.37
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 2.579e-12 0.31
TTHY_HUMAN TTR Transthyretin 2.941e-12 0.53
1433G_HUMAN YWHAG 14-3-3 protein gamma 5.432e-12 0.44
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 9.6e-12 0.37
B3DH72_DANRE oprd1b Opioid receptor, delta 1b 1.15e-11 0.28
O57585_DANRE oprd1a Opioid receptor homologue 1.15e-11 0.28
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 1.421e-11 0.34
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 1.513e-11 0.44
LGUL_YEAST GLO1 Lactoylglutathione lyase 1.554e-11 0.31
OPRD_HUMAN OPRD1 Delta-type opioid receptor 2.223e-11 0.38
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.335e-11 0.33
COMT_PIG COMT Catechol O-methyltransferase 2.548e-11 0.36
MDM4_HUMAN MDM4 Protein Mdm4 2.878e-11 0.32
THA_HUMAN THRA Thyroid hormone receptor alpha 6.784e-11 0.52
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 1.289e-10 0.28
GRIK2_RAT Grik2 Glutamate receptor ionotropic, kainate 2 1.86e-10 0.33
NEP_PIG MME Neprilysin 2.659e-10 0.30
DPP9_HUMAN DPP9 Dipeptidyl peptidase 9 2.876e-10 0.31
CASR_HUMAN CASR Extracellular calcium-sensing receptor 2.954e-10 0.37
GP142_HUMAN GPR142 Probable G-protein coupled receptor 142 6.724e-10 0.33
JUN_HUMAN JUN Transcription factor AP-1 1.3e-09 0.53
DOPO_RAT Dbh Dopamine beta-hydroxylase 1.705e-09 0.32
CAH14_HUMAN CA14 Carbonic anhydrase 14 2.21e-09 0.39
PTPRA_HUMAN PTPRA Receptor-type tyrosine-protein phosphatase alpha 2.433e-09 0.54
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 2.631e-09 0.36
FOS_HUMAN FOS Proto-oncogene c-Fos 3.547e-09 0.53
CAH2_HUMAN CA2 Carbonic anhydrase 2 3.634e-09 0.48
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 3.698e-09 0.53
CAH7_HUMAN CA7 Carbonic anhydrase 7 4.6e-09 0.41
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 4.866e-09 0.34
POLG_CXB3N Genome polyprotein 5.044e-09 0.31
Q9BEG3_BOVIN 5-lipoxygenase 5.829e-09 0.53
ELAS_PSEAE lasB Elastase 5.917e-09 0.29
POLG_DEN2P Genome polyprotein 6.379e-09 0.39
DPP2_HUMAN DPP7 Dipeptidyl peptidase 2 6.508e-09 0.31
THB_HUMAN THRB Thyroid hormone receptor beta 6.749e-09 0.52
DHPR_RAT Qdpr Dihydropteridine reductase 7.149e-09 0.30
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 7.167e-09 0.33
SYUA_HUMAN SNCA Alpha-synuclein 1.01e-08 0.37
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 1.047e-08 0.36
Q49PX0_9POXV N1L N1L 1.229e-08 0.31
DOPO_HUMAN DBH Dopamine beta-hydroxylase 1.674e-08 0.32
RASH_HUMAN HRAS GTPase HRas 1.793e-08 0.32
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.115e-08 0.34
DHPR_HUMAN QDPR Dihydropteridine reductase 2.237e-08 0.30
AMP1_PLAFQ M1 family aminopeptidase 2.744e-08 0.31
PPBN_HUMAN ALPG Alkaline phosphatase, germ cell type 4.382e-08 0.68
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 4.408e-08 0.40
CAH6_HUMAN CA6 Carbonic anhydrase 6 4.669e-08 0.39
GP142_MOUSE Gpr142 Probable G-protein coupled receptor 142 5.984e-08 0.33
SC6A5_RAT Slc6a5 Sodium- and chloride-dependent glycine transporter 2 5.999e-08 0.30
NEP_RAT Mme Neprilysin 6.468e-08 0.48
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 1.141e-07 0.35
NEP_HUMAN MME Neprilysin 1.152e-07 0.43
MEX5_CAEEL mex-5 Zinc finger protein mex-5 1.291e-07 0.53
O49150_SOLTU Lipoxygenase 1.526e-07 0.38
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 1.603e-07 0.53
ALBU_BOVIN ALB Serum albumin 1.848e-07 0.33
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 1.934e-07 0.29
DPP8_HUMAN DPP8 Dipeptidyl peptidase 8 2.47e-07 0.31
ACE_HUMAN ACE Angiotensin-converting enzyme 2.791e-07 0.43
PGH2_BOVIN PTGS2 Prostaglandin G/H synthase 2 3.409e-07 0.33
A4_HUMAN APP Amyloid-beta precursor protein 3.811e-07 0.53
PPO2_AGABI PPO2 Polyphenol oxidase 2 4.161e-07 0.38
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 4.953e-07 0.53
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 5.457e-07 0.31
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 8.338e-07 0.33
OPRX_CAVPO OPRL1 Nociceptin receptor 9.034e-07 0.31
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 9.659e-07 0.38
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.049e-06 0.38
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 1.072e-06 0.30
LGUL_HUMAN GLO1 Lactoylglutathione lyase 1.296e-06 0.31
BLA2_BACCE blm Metallo-beta-lactamase type 2 1.435e-06 0.32
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.721e-06 0.50
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 1.788e-06 0.28
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 2.155e-06 0.30
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 2.385e-06 0.53
LOX5_MOUSE Alox5 Arachidonate 5-lipoxygenase 2.394e-06 0.53
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 2.459e-06 0.44
CAH3_HUMAN CA3 Carbonic anhydrase 3 2.822e-06 0.38
TYRO_HUMAN TYR Tyrosinase 2.966e-06 0.29
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 4.296e-06 0.30
KMO_RAT Kmo Kynurenine 3-monooxygenase 4.761e-06 0.36
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 5.183e-06 0.45
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 6.235e-06 0.29
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 6.775e-06 0.31
CAH4_HUMAN CA4 Carbonic anhydrase 4 8.195e-06 0.47
NOX4_HUMAN NOX4 NADPH oxidase 4 9.864e-06 0.34

Zopiclone

GBRA4_HUMAN GABRA4 Gamma-aminobutyric acid receptor subunit alpha-4 2.504e-10 1.00
GBRA1_HUMAN GABRA1 Gamma-aminobutyric acid receptor subunit alpha-1 0.02462 1.00
NPBW1_MOUSE Npbwr1 Neuropeptides B/W receptor type 1 6.084e-51 0.33
S6A15_HUMAN SLC6A15 Sodium-dependent neutral amino acid transporter B(0)AT2 7.049e-38 0.32
HRH1_RAT Hrh1 Histamine H1 receptor 4.36e-23 0.33
SMO_HUMAN SMO Smoothened homolog 7.233e-21 0.38
Q91ZY3_CAVPO HRH4 Histamine H4 receptor 1.523e-18 0.29
CEGT_HUMAN UGCG Ceramide glucosyltransferase 4.441e-16 0.32
HRH3_HUMAN HRH3 Histamine H3 receptor 1.078e-11 0.34
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 1.684e-11 0.33
PDE10_RAT Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 2.545e-11 0.43
FNTA_HUMAN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 8.69e-11 0.33
MEP2_YEAST MEP2 Ammonium transporter MEP2 2.659e-10 0.30
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 2.536e-08 0.29
ADA10_HUMAN ADAM10 Disintegrin and metalloproteinase domain-containing protein 10 2.498e-07 0.28
NK3R_HUMAN TACR3 Neuromedin-K receptor 6.973e-07 0.32
GYRB_MYCS2 gyrB DNA gyrase subunit B 9.396e-07 0.29
LIPS_HUMAN LIPE Hormone-sensitive lipase 3.26e-06 0.35
AGP1_YEAST AGP1 General amino acid permease AGP1 3.933e-06 0.30
P2Y12_RAT P2ry12 P2Y purinoceptor 12 6.582e-06 0.29
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 7.112e-06 0.29

Fluoxymesterone

ANDR_HUMAN AR Androgen receptor 2.039e-09 1.00
ATTY_RAT Tat Tyrosine aminotransferase 4.749e-89 0.34
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 2.898e-72 0.54
Q690N0_BOVIN PGR Progesterone receptor 6.755e-71 0.56
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.093e-67 0.71
GCR_RAT Nr3c1 Glucocorticoid receptor 1.514e-56 0.54
CP19A_HUMAN CYP19A1 Aromatase 1.502e-51 0.41
PRGR_RAT Pgr Progesterone receptor 8.737e-44 0.36
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.163e-40 0.33
GCR_MOUSE Nr3c1 Glucocorticoid receptor 3.653e-33 0.39
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 3.672e-30 0.41
SHBG_RAT Shbg Sex hormone-binding globulin 3.343e-26 0.32
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 5.821e-24 0.34
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 2.847e-23 0.29
GCR_HUMAN NR3C1 Glucocorticoid receptor 1.524e-21 0.67
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 3.159e-21 0.34
ANDR_RAT Ar Androgen receptor 5.357e-20 0.56
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 5.756e-20 0.34
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 7.754e-19 0.39
PRGR_RABIT PGR Progesterone receptor 4.441e-16 0.34
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 7.516e-14 0.34
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 2.682e-13 0.34
GLNA_HUMAN GLUL Glutamine synthetase 7.039e-10 0.31
ERG2_YEAST ERG2 C-8 sterol isomerase 9.763e-10 0.41
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 9.861e-10 0.34
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 1.012e-09 0.28
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 4.029e-09 0.35
ANDR_MOUSE Ar Androgen receptor 6.335e-09 0.41
MCR_HUMAN NR3C2 Mineralocorticoid receptor 1.094e-08 0.40
IL6_HUMAN IL6 Interleukin-6 6.548e-08 0.31
PPO2_AGABI PPO2 Polyphenol oxidase 2 9.321e-07 0.42

Rifaximin

NR1I2_HUMAN NR1I2 Nuclear receptor subfamily 1 group I member 2 1.301e-08 1.00
STRP_STRP1 ska Streptokinase A 0.2253 1.00
POL_WMSV pol Gag-Pol polyprotein 6.185e-177 0.65
RPOB_MYCTU rpoB DNA-directed RNA polymerase subunit beta 4.097e-151 0.66
DPOLB_MOUSE Polb DNA polymerase beta 3.453e-114 0.65
SO2B1_HUMAN SLCO2B1 Solute carrier organic anion transporter family member 2B1 9.369e-88 0.70
SO1B3_HUMAN SLCO1B3 Solute carrier organic anion transporter family member 1B3 9.087e-83 0.70
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 1.729e-59 0.70
ABCBB_RAT Abcb11 Bile salt export pump 9.645e-28 0.70
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 3.331e-16 0.70
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 2.254e-14 0.70

Orphenadrine

SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.311e-07 1.00
HRH1_RAT Hrh1 Histamine H1 receptor 1.281e-06 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 1.307e-06 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 3.991e-06 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 4.254e-06 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 2.431e-05 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.0002683 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 0.0002921 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 0.0002941 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.0009982 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.001408 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.001886 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.001935 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.1054 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.1707 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.1989 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.341 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.9232 1.00
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 3.063e-31 0.31
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 6.927e-30 0.49
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 6.813e-23 0.47
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 8.91e-18 0.33
ATP6_MYCTU atpB ATP synthase subunit a 4.169e-17 0.31
ATPA_MYCTU atpA ATP synthase subunit alpha 4.169e-17 0.31
ATPB_MYCTU atpD ATP synthase subunit beta 4.169e-17 0.31
ATPE_MYCTU atpC ATP synthase epsilon chain 4.169e-17 0.31
ATPFD_MYCTU atpFH ATP synthase subunit b-delta 4.169e-17 0.31
ATPF_MYCTU atpF ATP synthase subunit b 4.169e-17 0.31
ATPG_MYCTU atpG ATP synthase gamma chain 4.169e-17 0.31
ATPL_MYCTU atpE ATP synthase subunit c 4.169e-17 0.31
CP51_SORBI CYP51 Obtusifoliol 14-alpha demethylase 1.11e-15 0.30
AMYP_RAT Amy2 Pancreatic alpha-amylase 1.131e-13 0.30
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 8.917e-13 0.31
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 9.192e-12 0.29
ANM1_RAT Prmt1 Protein arginine N-methyltransferase 1 9.7e-12 0.29
US28_HCMVA US28 G-protein coupled receptor homolog US28 3.542e-11 0.30
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 2.685e-09 0.73
HRH1_CAVPO HRH1 Histamine H1 receptor 6.717e-09 0.73
UR2R_HUMAN UTS2R Urotensin-2 receptor 6.736e-09 0.33
Q9WTR4_RAT Slc6a2 Transporter 8.684e-09 0.35
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.704e-07 0.35
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 2.83e-06 0.33
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 3.213e-06 0.28
ACHP_LYMST Acetylcholine-binding protein 5.027e-06 0.58

Decitabine

DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 2.613e-07 1.00
CDD_HUMAN CDA Cytidine deaminase 1.05e-80 0.37
A3RLP8_CHV1 UL23 Thymidine kinase 4.226e-80 0.48
TYSY_LACCA thyA Thymidylate synthase 1.807e-79 0.44
CDD_MOUSE Cda Cytidine deaminase 9.469e-75 0.37
AA1R_RAT Adora1 Adenosine receptor A1 2.353e-73 0.57
KITH_VZVD TK Thymidine kinase 1.858e-71 0.48
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 7.507e-65 0.41
P2RY1_RAT P2ry1 P2Y purinoceptor 1 8.617e-64 0.30
KTHY_HUMAN DTYMK Thymidylate kinase 2.691e-58 0.34
KITH_VZVO TK Thymidine kinase 9.733e-58 0.44
AA2AR_RAT Adora2a Adenosine receptor A2a 3.115e-57 0.39
AA1R_CAVPO ADORA1 Adenosine receptor A1 1.082e-54 0.41
ADA_MOUSE Ada Adenosine deaminase 2.014e-54 0.37
DNK_DROME dnk Deoxynucleoside kinase 1.214e-52 0.32
TYSY_BOVIN TYMS Thymidylate synthase 1.856e-52 0.36
RNAS1_HUMAN RNASE1 Ribonuclease pancreatic 3.419e-52 0.37
RNAS2_HUMAN RNASE2 Non-secretory ribonuclease 3.419e-52 0.37
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 8.925e-51 0.37
P2Y11_HUMAN P2RY11 P2Y purinoceptor 11 2.861e-50 0.41
KITM_HUMAN TK2 Thymidine kinase 2, mitochondrial 1.299e-49 0.34
KITH_RAT Tk1 Thymidine kinase, cytosolic 5.406e-47 0.39
KTHY_MYCTU tmk Thymidylate kinase 1.005e-45 0.47
TYSY_MYCTU thyA Thymidylate synthase ThyA 4.538e-44 0.35
ADA_BOVIN ADA Adenosine deaminase 2.163e-42 0.56
SAHH_PLAF7 Adenosylhomocysteinase 4.026e-42 0.35
KITH_HHV1S TK Thymidine kinase 1.765e-41 0.48
D3ZGQ2_RAT Tk2 Thymidine kinase 2 2.269e-41 0.33
DPOLB_HUMAN POLB DNA polymerase beta 3.774e-41 0.46
KITH_HUMAN TK1 Thymidine kinase, cytosolic 4.636e-41 0.48
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 8.267e-40 0.43
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 2.006e-39 0.31
HSP7C_BOVIN HSPA8 Heat shock cognate 71 kDa protein 1.023e-37 0.30
WALK_STAAU walK Sensor protein kinase WalK 1.023e-37 0.30
ENPP1_RAT Enpp1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 2.17e-37 0.31
MACD1_HUMAN MACROD1 ADP-ribose glycohydrolase MACROD1 1.195e-36 0.29
MACD2_HUMAN MACROD2 ADP-ribose glycohydrolase MACROD2 1.195e-36 0.29
P2RY4_RAT P2ry4 P2Y purinoceptor 4 7.259e-36 0.29
P2RX5_RAT P2rx5 P2X purinoceptor 5 7.471e-36 0.29
P2RX6_RAT P2rx6 P2X purinoceptor 6 7.471e-36 0.29
POLG_POL1M Genome polyprotein 1.215e-35 0.28
ADCY5_RAT Adcy5 Adenylate cyclase type 5 4.209e-34 0.57
Q9HX69_PSEAE rocR RocR 6.1e-31 0.32
THYX_MYCTU thyX Flavin-dependent thymidylate synthase 3.309e-30 0.35
PYRF_YEAST URA3 Orotidine 5'-phosphate decarboxylase 2.115e-29 0.29
AA1R_CHICK ADORA1 Adenosine receptor A1 2.506e-28 0.32
AA3R_HUMAN ADORA3 Adenosine receptor A3 8.165e-26 0.38
ADA_HUMAN ADA Adenosine deaminase 2.329e-25 0.49
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 3.717e-25 0.40
Q4VQ11_PIG Adenosine receptor A1 5.147e-25 0.34
Q3ZDS5_9HEPC NS5B 1.444e-23 0.29
KAD3_RAT Ak3 GTP:AMP phosphotransferase AK3, mitochondrial 1.926e-23 0.29
AMPD1_RABIT AMPD1 AMP deaminase 1 6.377e-23 0.28
BIP_HUMAN HSPA5 Endoplasmic reticulum chaperone BiP 3.531e-21 0.31
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 9.598e-21 0.33
AA1R_HUMAN ADORA1 Adenosine receptor A1 3.358e-20 0.38
AA3R_RAT Adora3 Adenosine receptor A3 1.543e-19 0.37
KITH_HHV1 TK Thymidine kinase 1.743e-19 0.36
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 2.076e-19 0.41
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 3.118e-19 0.29
KAD2_RAT Ak2 Adenylate kinase 2, mitochondrial 3.615e-18 0.29
SAHH_HUMAN AHCY Adenosylhomocysteinase 5.153e-18 0.36
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 3.284e-17 0.31
OXGR1_RAT Oxgr1 2-oxoglutarate receptor 1 1.11e-16 0.29
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 1.11e-16 0.29
P2RX4_RAT P2rx4 P2X purinoceptor 4 1.11e-16 0.29
Q6L709_HHV2 TK Thymidine kinase 3.331e-16 0.36
Q8II92_PLAF7 Deoxyuridine 5'-triphosphate nucleotidohydrolase 4.441e-16 0.31
TYSY_MOUSE Tyms Thymidylate synthase 2.22e-15 0.47
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 5.662e-15 0.32
PUR6_CHICK AIRC Multifunctional protein ADE2 1.01e-14 0.32
G3P_HUMAN GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1.121e-14 0.39
IF4E_RABIT EIF4E Eukaryotic translation initiation factor 4E 1.754e-14 0.28
5NTD_HUMAN NT5E 5'-nucleotidase 1.832e-14 0.44
O39930_9HEPC NS5b RNA-directed RNA polymerase 3.819e-14 0.33
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 7.927e-14 0.43
HSP7C_HUMAN HSPA8 Heat shock cognate 71 kDa protein 8.56e-14 0.31
GPR17_HUMAN GPR17 Uracil nucleotide/cysteinyl leukotriene receptor 7.555e-13 0.36
ADK_HUMAN ADK Adenosine kinase 8.926e-13 0.38
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 1.4e-12 0.31
MTAP_MOUSE Mtap S-methyl-5'-thioadenosine phosphorylase 9.7e-12 0.29
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 4.45e-11 0.40
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 6.723e-11 0.32
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 7.29e-11 0.36
SAHH_MOUSE Ahcy Adenosylhomocysteinase 7.306e-11 0.29
ADCY2_RAT Adcy2 Adenylate cyclase type 2 7.946e-11 0.29
RAB7A_HUMAN RAB7A Ras-related protein Rab-7a 3.111e-10 0.32
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 3.836e-10 0.32
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 2.795e-09 0.31
ADK_TOXGO AK Adenosine kinase 5.709e-09 0.36
Q03732_HBV HBcAg Capsid protein 8.121e-09 0.48
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 1.181e-08 0.34
E1BN64_BOVIN PDE3B Phosphodiesterase 1.322e-08 0.29
AA1R_BOVIN ADORA1 Adenosine receptor A1 7.88e-08 0.37
Q9WJQ2_9HIV1 reverse transcriptase Reverse transcriptase protein 1.403e-07 0.67
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 1.601e-07 0.37
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 1.62e-07 0.34
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 6.751e-07 0.36
IF4E_MOUSE Eif4e Eukaryotic translation initiation factor 4E 7.69e-07 0.29
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 9.611e-07 0.36
TYSY_HUMAN TYMS Thymidylate synthase 1.331e-06 0.41
5NTD_RAT Nt5e 5'-nucleotidase 2.02e-06 0.30
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.989e-06 0.33
Q9WKE8_9HIV1 reverse transcriptase Reverse transcriptase 3.598e-06 0.67
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 5.02e-06 0.29
P2Y12_RAT P2ry12 P2Y purinoceptor 12 5.771e-06 0.30

Bepridil

CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 5.715e-06 1.00
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 5.715e-06 1.00
LEF_BACAN lef Lethal factor 0.001556 1.00
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 0.02632 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.0461 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9985 1.00
CETP_RABIT CETP Cholesteryl ester transfer protein 5.105e-37 0.33
RORG_HUMAN RORC Nuclear receptor ROR-gamma 3.117e-18 0.36
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 5.729e-14 0.29
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 7.453e-07 0.32
CETP_HUMAN CETP Cholesteryl ester transfer protein 1.185e-06 0.33
EST1_PIG Liver carboxylesterase 7.157e-06 0.28

Procarbazine

CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.004104 1.00
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 1.819e-45 0.31
Q6DMN0_TOXGO CPL Cathepsin L 3.236e-40 0.33
DYR_ENTFC folA Dihydrofolate reductase 6.393e-39 0.31
ECR_CHITE EcR Ecdysone receptor 1.775e-36 0.29
ECR_HELVI EcR Ecdysone receptor 1.775e-36 0.29
O45117_CHITE USP-1 Ultraspiracle 1.775e-36 0.29
Q6IVK1_PLOIN USP 1.775e-36 0.29
Q6RVD3_PLOIN Ecdysone receptor 1.775e-36 0.29
Q7SIF6_HELVI Gene regulation protein 1.775e-36 0.29
Q8I1M8_CHISP CsUSP Ultraspiracle 1.775e-36 0.29
Q8MYA6_CHISP CsEcR-B1 Ecdysone receptor B1 isoform 1.775e-36 0.29
Q962I5_LUCCU Ultraspiracle protein 1.775e-36 0.29
USP_CHOFU USP Protein ultraspiracle homolog 1.775e-36 0.29
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.255e-34 0.35
PEPT1_DERPT DERP1 Peptidase 1 2.104e-28 0.32
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 1.344e-26 0.33
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 3.863e-25 0.33
KLKB1_HUMAN KLKB1 Plasma kallikrein 7.944e-25 0.40
HDAC1_HUMAN HDAC1 Histone deacetylase 1 2.424e-22 0.37
NR1H4_HUMAN NR1H4 Bile acid receptor 7.209e-22 0.43
LPXC_ECOLI lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.095e-21 0.34
HDAC6_HUMAN HDAC6 Histone deacetylase 6 3.33e-21 0.40
CTRB_BOVIN Chymotrypsinogen B 3.712e-21 0.31
C6ARS9_RHILS lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 6.654e-21 0.33
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 1.667e-20 0.33
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 7.515e-19 0.33
PAPA1_CARPA Papain 2.348e-18 0.33
Q8IM16_PLAF7 Plasmepsin IV 2.375e-18 0.29
Q4W6C8_LEPDE LdUSP Ultraspiracle 3.334e-18 0.29
Q4W6D0_LEPDE LdEcR-A Ecdysone receptor A isoform 3.334e-18 0.29
E3UJZ5_SPOLI Ecdysone receptor 4.117e-18 0.31
NEC2_HUMAN PCSK2 Neuroendocrine convertase 2 9.056e-18 0.28
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.319e-17 0.43
AOC3_MOUSE Aoc3 Membrane primary amine oxidase 1.11e-16 0.32
ECR_BOMMO EcR Ecdysone receptor 1.11e-16 0.33
FOLC_HUMAN FPGS Folylpolyglutamate synthase, mitochondrial 1.11e-16 0.33
HDAC8_HUMAN HDAC8 Histone deacetylase 8 2.22e-16 0.40
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 2.22e-16 0.35
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 4.441e-16 0.31
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 5.551e-16 0.33
TRY1_HUMAN PRSS1 Trypsin-1 7.772e-16 0.33
Q9GSG8_AEDAE Ultraspiracle isoform-A 3.22e-15 0.29
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 4.885e-15 0.35
PPAP_HUMAN ACP3 Prostatic acid phosphatase 8.105e-15 0.29
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 9.104e-15 0.33
CATG_HUMAN CTSG Cathepsin G 1.099e-14 0.33
HDAC1_MOUSE Hdac1 Histone deacetylase 1 1.932e-14 0.31
GBRA5_HUMAN GABRA5 Gamma-aminobutyric acid receptor subunit alpha-5 4.086e-14 0.34
KPCD1_HUMAN PRKD1 Serine/threonine-protein kinase D1 6.439e-14 0.42
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 1.905e-13 0.33
CAH2_HUMAN CA2 Carbonic anhydrase 2 2.88e-13 0.38
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 5.66e-13 0.31
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 6.108e-13 0.28
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 6.108e-13 0.28
PCSK7_HUMAN PCSK7 Proprotein convertase subtilisin/kexin type 7 6.108e-13 0.28
HDAC2_HUMAN HDAC2 Histone deacetylase 2 1.123e-12 0.36
TRY1_RAT Prss1 Anionic trypsin-1 1.732e-12 0.29
UPAR_RAT Plaur Urokinase plasminogen activator surface receptor 1.732e-12 0.29
AOC2_HUMAN AOC2 Retina-specific copper amine oxidase 2.246e-12 0.30
THRB_RAT F2 Prothrombin 3.165e-12 0.29
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 4.92e-12 0.31
H9B8T9_CAPHI CTSB Cathepsin B 8.815e-12 0.38
AMPN_HUMAN ANPEP Aminopeptidase N 1.975e-11 0.33
ACACB_HUMAN ACACB Acetyl-CoA carboxylase 2 2.912e-11 0.49
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 3.661e-11 0.33
CTNB1_HUMAN CTNNB1 Catenin beta-1 4.229e-11 0.31
HDAC4_HUMAN HDAC4 Histone deacetylase 4 5.567e-11 0.39
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 5.594e-11 0.31
AMPN_PIG ANPEP Aminopeptidase N 6.001e-11 0.33
POLG_CXB3N Genome polyprotein 6.024e-11 0.30
AMP1_PLAFQ M1 family aminopeptidase 8.76e-11 0.30
PRKX_HUMAN PRKX cAMP-dependent protein kinase catalytic subunit PRKX 9.514e-11 0.33
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 1.105e-10 0.29
CAH4_BOVIN CA4 Carbonic anhydrase 4 1.235e-10 0.38
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.762e-10 0.35
PLMN_RAT Plg Plasminogen 2.22e-10 0.29
USP_DROME usp Protein ultraspiracle 2.408e-10 0.30
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 5.607e-10 0.33
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 5.776e-10 0.33
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.005e-09 0.38
KS6A5_HUMAN RPS6KA5 Ribosomal protein S6 kinase alpha-5 1.469e-09 0.33
CATL1_BOVIN CTSL Cathepsin L1 1.584e-09 0.33
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 2.064e-09 0.33
ITA5_HUMAN ITGA5 Integrin alpha-5 2.416e-09 0.34
CATB_HUMAN CTSB Cathepsin B 2.482e-09 0.34
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 2.705e-09 0.31
ECR_LUCCU EcR Ecdysone receptor 2.988e-09 0.29
KLK1_HUMAN KLK1 Kallikrein-1 3.141e-09 0.36
PPCE_PIG PREP Prolyl endopeptidase 3.404e-09 0.34
UR2R_HUMAN UTS2R Urotensin-2 receptor 7.768e-09 0.31
CATK_HUMAN CTSK Cathepsin K 8.91e-09 0.35
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 1.134e-08 0.29
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 1.408e-08 0.31
ECR_DROME EcR Ecdysone receptor 1.506e-08 0.30
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 1.665e-08 0.28
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 2.89e-08 0.33
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 3.05e-08 0.35
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 3.185e-08 0.33
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 6.381e-08 0.31
KAPCA_HUMAN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 7.786e-08 0.33
MRCKA_HUMAN CDC42BPA Serine/threonine-protein kinase MRCK alpha 7.921e-08 0.33
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 1.112e-07 0.35
GATA4_MOUSE Gata4 Transcription factor GATA-4 1.188e-07 0.31
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 1.188e-07 0.31
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 1.521e-07 0.29
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 1.646e-07 0.33
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.778e-07 0.40
CYNT_HELPY cynT Carbonic anhydrase 1.962e-07 0.35
Q38C41_TRYB2 Phosphotransferase 2.046e-07 0.32
Q72874_9HIV1 pol Pol polyprotein 2.084e-07 0.37
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 2.151e-07 0.37
CATL1_HUMAN CTSL Cathepsin L1 2.521e-07 0.35
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 2.76e-07 0.33
LPXC_PSEAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 3.508e-07 0.43
DYR_RAT Dhfr Dihydrofolate reductase 3.733e-07 0.31
HDAC5_HUMAN HDAC5 Histone deacetylase 5 4.226e-07 0.35
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 5.622e-07 0.28
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 6.255e-07 0.33
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 7.944e-07 0.32
NEK4_HUMAN NEK4 Serine/threonine-protein kinase Nek4 9.277e-07 0.31
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 1.071e-06 0.33
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.395e-06 0.35
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.448e-06 0.35
O77240_CHOFU EcR Ecdysone receptor isoform A 1.482e-06 0.29
PRIO_MESAU PRNP Major prion protein 1.629e-06 0.30
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 1.854e-06 0.36
CTRA_BOVIN Chymotrypsinogen A 2.358e-06 0.36
A5H660_SCHMA HDAC8 Histone deacetylase 8 2.767e-06 0.38
CMA1_HUMAN CMA1 Chymase 2.943e-06 0.33
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 3.247e-06 0.33
ACE_HUMAN ACE Angiotensin-converting enzyme 3.846e-06 0.29
CBPA1_BOVIN CPA1 Carboxypeptidase A1 3.913e-06 0.34
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 4.143e-06 0.35
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 4.29e-06 0.31
CAH2_BOVIN CA2 Carbonic anhydrase 2 4.349e-06 0.33
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 5.159e-06 0.35
CP26A_HUMAN CYP26A1 Cytochrome P450 26A1 6.248e-06 0.31
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 6.631e-06 0.32
CATS_HUMAN CTSS Cathepsin S 7.355e-06 0.35
AGP1_YEAST AGP1 General amino acid permease AGP1 7.953e-06 0.28
CPNS1_PIG CAPNS1 Calpain small subunit 1 8.822e-06 0.30
STABP_HUMAN STAMBP STAM-binding protein 9.636e-06 0.29
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 9.867e-06 0.37

Clarithromycin

STRP_STRP1 ska Streptokinase A 0.004985 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.2687 1.00
A5A4K8_RABIT MLNR Motilin receptor 6.233e-252 0.92
ABCBB_HUMAN ABCB11 Bile salt export pump 4.628e-30 0.76
Q9XYC7_PLAFA HDAC1 Histone deacetylase 9.161e-26 0.36
MTLR_HUMAN MLNR Motilin receptor 6.619e-20 0.92
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.104e-10 0.53
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 1.022e-09 0.45
GNRHR_HUMAN GNRHR Gonadotropin-releasing hormone receptor 9.13e-07 0.68

Gliquidone

CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.01205 1.00
MGAT3_HUMAN MGAT3 Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase 1.708e-60 0.32
MMP13_RAT Mmp13 Collagenase 3 1.224e-48 0.33
GHSR_RABIT GHSR Growth hormone secretagogue receptor type 1 1.332e-41 0.33
MTR1B_CHICK Melatonin receptor type 1B 8.997e-40 0.32
SCNNA_MOUSE Scnn1a Amiloride-sensitive sodium channel subunit alpha 7.546e-37 0.34
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 1.112e-32 0.30
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 1.554e-30 0.30
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 5.333e-30 0.37
ADA33_HUMAN ADAM33 Disintegrin and metalloproteinase domain-containing protein 33 1.607e-28 0.29
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 3.999e-25 0.33
CRFR2_HUMAN CRHR2 Corticotropin-releasing factor receptor 2 2.768e-24 0.39
MMP1_HUMAN MMP1 Interstitial collagenase 1.447e-22 0.35
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 2.053e-22 0.37
TGM2_MOUSE Tgm2 Protein-glutamine gamma-glutamyltransferase 2 8.349e-22 0.35
MMP7_HUMAN MMP7 Matrilysin 1.608e-21 0.33
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 6.172e-21 0.34
ADA17_RAT Adam17 Disintegrin and metalloproteinase domain-containing protein 17 2.383e-20 0.28
ABCC8_HUMAN ABCC8 ATP-binding cassette sub-family C member 8 5.714e-20 0.49
ABCBB_RAT Abcb11 Bile salt export pump 1.063e-19 0.49
MMP3_HUMAN MMP3 Stromelysin-1 1.278e-18 0.35
MMP13_HUMAN MMP13 Collagenase 3 4.746e-18 0.35
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 1.055e-14 0.31
MOGT2_HUMAN MOGAT2 2-acylglycerol O-acyltransferase 2 1.243e-14 0.32
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 2.631e-14 0.49
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 3.209e-14 0.40
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 6.961e-14 0.34
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 1.892e-13 0.35
TIF1A_HUMAN TRIM24 Transcription intermediary factor 1-alpha 4.379e-13 0.31
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 8.973e-13 0.49
CP24A_RAT Cyp24a1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1.133e-11 0.28
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 4.447e-11 0.29
MMP2_HUMAN MMP2 72 kDa type IV collagenase 6.242e-11 0.35
KCNA1_HUMAN KCNA1 Potassium voltage-gated channel subfamily A member 1 8.147e-11 0.34
CASP7_HUMAN CASP7 Caspase-7 9.179e-11 0.33
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 1.946e-09 0.39
CHLE_MOUSE Bche Cholinesterase 3.052e-09 0.37
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 6.436e-09 0.33
MMP8_HUMAN MMP8 Neutrophil collagenase 6.931e-09 0.33
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 1.22e-08 0.31
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 2.223e-08 0.40
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 2.988e-08 0.33
CAH4_HUMAN CA4 Carbonic anhydrase 4 3.841e-08 0.32
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 8.995e-08 0.33
CP26B_HUMAN CYP26B1 Cytochrome P450 26B1 1.612e-07 0.31
LEP_ECOLI lepB Signal peptidase I 1.631e-07 0.29
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 2.674e-07 0.31
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 2.686e-07 0.31
OXYR_HUMAN OXTR Oxytocin receptor 3.504e-07 0.31
CASP3_HUMAN CASP3 Caspase-3 5.225e-07 0.33
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 8.676e-07 0.30
MMP12_MOUSE Mmp12 Macrophage metalloelastase 9.151e-07 0.30
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 1.732e-06 0.34
Q8WQX9_9TRYP PDEB1 Phosphodiesterase 1.76e-06 0.33
HRH3_HUMAN HRH3 Histamine H3 receptor 2.701e-06 0.47
CASP6_HUMAN CASP6 Caspase-6 3.07e-06 0.33
LPXC_PSEAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 6.083e-06 0.30
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 6.853e-06 0.31
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 7.658e-06 0.33

Flecainide

SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 0.02632 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.02788 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.1635 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.1939 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.2516 1.00
ARBK1_BOVIN GRK2 Beta-adrenergic receptor kinase 1 1.416e-79 0.31
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 5.936e-51 0.39
DRD2_CANLF DRD2 D(2) dopamine receptor 6.678e-41 0.32
AOC3_MOUSE Aoc3 Membrane primary amine oxidase 2.103e-31 0.31
W5VNF7_CANLF S1PR1 Sphingosine-1-phosphate receptor 1 1.431e-29 0.29
GRK5_BOVIN GRK5 G protein-coupled receptor kinase 5 2.015e-27 0.31
PPARA_CANLF PPARA Peroxisome proliferator-activated receptor alpha 1.268e-25 0.33
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 4.79e-19 0.40
H9EUW9_MACMU S1PR1 Sphingosine 1-phosphate receptor 1 4.879e-18 0.29
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 9.992e-16 0.30
CNR2_HUMAN CNR2 Cannabinoid receptor 2 2.22e-15 0.37
S1PR1_RAT S1pr1 Sphingosine 1-phosphate receptor 1 4.63e-14 0.29
TAAR1_RAT Taar1 Trace amine-associated receptor 1 1.084e-13 0.38
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 1.94e-13 0.42
S1PR1_MOUSE S1pr1 Sphingosine 1-phosphate receptor 1 2.341e-12 0.29
IKKB_HUMAN IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 2.78e-12 0.41
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 2.938e-12 0.34
LIPS_HUMAN LIPE Hormone-sensitive lipase 3.397e-12 0.34
ABCBB_RAT Abcb11 Bile salt export pump 5.251e-12 0.29
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 4.087e-10 0.38
RXFP1_HUMAN RXFP1 Relaxin receptor 1 5.942e-10 0.33
PPARD_MOUSE Ppard Peroxisome proliferator-activated receptor delta 1.648e-09 0.30
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 2.659e-09 0.34
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 8.515e-09 0.29
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 4.076e-08 0.31
TOPK_HUMAN PBK Lymphokine-activated killer T-cell-originated protein kinase 6.673e-08 0.41
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 6.729e-08 0.29
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 6.978e-08 0.29
TRAR_RHIRD traR Transcriptional activator protein TraR 1.13e-07 0.29
ACHA2_RAT Chrna2 Neuronal acetylcholine receptor subunit alpha-2 1.32e-07 0.31
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 4.379e-07 0.37
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 5.833e-07 0.30
Q25856_PLAFA PFG6PD Glucose-6-phosphate dehydrogenase 1.122e-06 0.34
HNF4A_RAT Hnf4a Hepatocyte nuclear factor 4-alpha 6.24e-06 0.33
SAHH_HUMAN AHCY Adenosylhomocysteinase 7.06e-06 0.39

Ciclopirox

Q8IL32_PLAF7 Heat shock protein 90, putative 0.04879 1.00
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 0.4626 1.00
Q3V4E6_MAIZE ACCase Acetyl-CoA carboxylase 9.719e-24 0.29
IDHC_HUMAN IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic 9.605e-11 0.44
O96526_LEIMA CRK3 Cdc2-related kinase 2.049e-10 0.30
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 1.223e-09 0.35
OXDA_PIG DAO D-amino-acid oxidase 4.733e-09 0.33
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 9.521e-09 0.35

Halofantrine

Q8IL32_PLAF7 Heat shock protein 90, putative 0.1267 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.6311 1.00
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 0.6738 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.7197 1.00
RORB_HUMAN RORB Nuclear receptor ROR-beta 1.219e-11 0.34
RORA_HUMAN RORA Nuclear receptor ROR-alpha 8.321e-10 0.34

Pemoline

SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.8715 1.00
PH4H_RAT Pah Phenylalanine-4-hydroxylase 1.652e-55 0.31
CP2B6_HUMAN CYP2B6 Cytochrome P450 2B6 3.058e-36 0.29
TGT_HUMAN QTRT1 Queuine tRNA-ribosyltransferase catalytic subunit 1 5.379e-25 0.31

Cilostazol

CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.8832 1.00
Q6S996_LEIMA PDEB1 Phosphodiesterase 1.968e-44 0.35
Q8WQX9_9TRYP PDEB1 Phosphodiesterase 5.281e-29 0.35
KPYM_HUMAN PKM Pyruvate kinase PKM 3.832e-24 0.32
H10_HUMAN H1-0 Histone H1.0 5.223e-20 0.38
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 1.11e-16 0.48
A0A0E7NXW5_STAAU birA Bifunctional ligase/repressor BirA 3.922e-13 0.29
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 8.555e-12 0.51
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.14e-10 0.42
HRH3_RAT Hrh3 Histamine H3 receptor 2.972e-09 0.34
HRH3_HUMAN HRH3 Histamine H3 receptor 8.059e-09 0.35
CHLE_HORSE BCHE Cholinesterase 1.568e-07 0.45
DRD5_HUMAN DRD5 D(1B) dopamine receptor 3.471e-07 0.38
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 2.775e-06 0.61
ACES_RAT Ache Acetylcholinesterase 3.004e-06 0.47
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 3.166e-06 0.46
OGT1_HUMAN OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 4.283e-06 0.29
DRD4_HUMAN DRD4 D(4) dopamine receptor 5.103e-06 0.42
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 9.449e-06 0.31

Levacetylmethadol

KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9677 1.00
AMYP_RAT Amy2 Pancreatic alpha-amylase 1.668e-64 0.32
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 2.257e-33 0.39
K4JQ36_LAOST ace2 Carboxylic ester hydrolase 6.661e-16 0.30
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 1.776e-15 0.29
PDS_SYNE7 pds 15-cis-phytoene desaturase 1.998e-15 0.31
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 6.106e-15 0.28
Q8WMX0_BOVIN Muscarinic receptor M1 4.853e-13 0.32
NEP_MOUSE Mme Neprilysin 5.125e-13 0.28
Q7YWJ9_MUSDO Ache Carboxylic ester hydrolase 3.048e-11 0.30
Q9NJH6_NEPCI AO-AChE Ace-orthologous acetylcholinesterase 3.048e-11 0.30
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.031e-07 0.29
KCNN4_HUMAN KCNN4 Intermediate conductance calcium-activated potassium channel protein 4 5.974e-07 0.31
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 1.7e-06 0.29
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 2.482e-06 0.29
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 2.835e-06 0.31
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 7.795e-06 0.33

Lisdexamfetamine

CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 1.13e-194 0.44
NEP_RABIT MME Neprilysin 1.421e-169 0.43
CATB_BOVIN CTSB Cathepsin B 2.361e-156 0.48
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 4.436e-144 0.49
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 8.159e-134 0.46
THER_BACTH npr Thermolysin 2.023e-130 0.39
AMPN_PIG ANPEP Aminopeptidase N 5.542e-130 0.47
OPRM_RAT Oprm1 Mu-type opioid receptor 3.194e-124 0.50
KLK3_HUMAN KLK3 Prostate-specific antigen 5.783e-123 0.48
CBX7_HUMAN CBX7 Chromobox protein homolog 7 2.906e-122 0.34
CD36_RAT Cd36 Platelet glycoprotein 4 3.31e-120 0.41
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 2.931e-119 0.33
NEP_RAT Mme Neprilysin 4.417e-118 0.41
PRSS8_HUMAN PRSS8 Prostasin 9.904e-115 0.41
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 1.682e-114 0.42
CPNS1_PIG CAPNS1 Calpain small subunit 1 1.955e-111 0.41
OPRD_RAT Oprd1 Delta-type opioid receptor 3.692e-111 0.47
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 8.665e-105 0.34
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 3.875e-104 0.40
Q72874_9HIV1 pol Pol polyprotein 7.475e-103 0.45
ACE_HUMAN ACE Angiotensin-converting enzyme 1.891e-101 0.41
CBX8_HUMAN CBX8 Chromobox protein homolog 8 5.58e-101 0.34
AMPB_RAT Rnpep Aminopeptidase B 1.713e-97 0.62
NEP_HUMAN MME Neprilysin 4.542e-97 0.42
CTRB_BOVIN Chymotrypsinogen B 1.283e-96 0.37
CBPA1_HUMAN CPA1 Carboxypeptidase A1 1.724e-96 0.38
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 1.091e-94 0.46
AMPL_PIG LAP3 Cytosol aminopeptidase 1.607e-94 0.35
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 2.153e-93 0.41
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.853e-92 0.46
NEP_MOUSE Mme Neprilysin 2.533e-92 0.55
OPRM_CAVPO OPRM1 Mu-type opioid receptor 4.631e-92 0.46
AMPN_HUMAN ANPEP Aminopeptidase N 2.158e-91 0.49
PAPA1_CARPA Papain 7.829e-91 0.44
POLG_DEN26 Genome polyprotein 9.547e-91 0.39
FCER2_HUMAN FCER2 Low affinity immunoglobulin epsilon Fc receptor 6.493e-90 0.36
CATB_HUMAN CTSB Cathepsin B 1.137e-86 0.44
MCA2_TRYBB MCA2 Metacaspase 5.186e-86 0.43
CATL1_HUMAN CTSL Cathepsin L1 4.331e-81 0.56
NK1R_RAT Tacr1 Substance-P receptor 1.688e-78 0.49
AMP1_PLAFQ M1 family aminopeptidase 3.179e-78 0.45
FURIN_HUMAN FURIN Furin 1.046e-74 0.39
NK2R_MESAU TACR2 Substance-K receptor 1.499e-74 0.37
MMP11_MOUSE Mmp11 Stromelysin-3 6.28e-74 0.34
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 4.31e-73 0.46
CATB_RAT Ctsb Cathepsin B 4.775e-73 0.38
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 1.055e-72 0.42
VM1B1_BOTAS Snake venom metalloproteinase BaP1 1.99e-72 0.47
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 9.367e-71 0.55
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 1.024e-70 0.44
POLG_WNV Genome polyprotein 1.065e-70 0.42
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 2.195e-70 0.50
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 5.216e-70 0.40
MMP3_HUMAN MMP3 Stromelysin-1 1.12e-68 0.50
EPOR_HUMAN EPOR Erythropoietin receptor 4.304e-68 0.41
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 6.314e-68 0.35
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.955e-67 0.39
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 3.439e-67 0.35
PHLC_BACCE plc Phospholipase C 1.169e-66 0.39
ACE_RABIT ACE Angiotensin-converting enzyme 1.283e-66 0.43
ACACB_HUMAN ACACB Acetyl-CoA carboxylase 2 1.425e-66 0.40
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 4.625e-66 0.44
QRFPR_HUMAN QRFPR Pyroglutamylated RF-amide peptide receptor 5.943e-66 0.44
AMPL_HUMAN LAP3 Cytosol aminopeptidase 1.189e-63 0.44
GRIA1_RAT Gria1 Glutamate receptor 1 1.236e-62 0.35
CYSP_TRYCR Cruzipain 2.17e-62 0.43
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 2.407e-62 0.36
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 1.536e-61 0.35
NPFF2_RAT Npffr2 Neuropeptide FF receptor 2 1.554e-61 0.42
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 2.062e-61 0.40
Q9NAW4_PLAFA Cysteine protease falcipain-3 3.931e-61 0.34
MMP8_RAT Mmp8 Neutrophil collagenase 1.566e-60 0.37
ACE_MOUSE Ace Angiotensin-converting enzyme 2.159e-60 0.41
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 1.843e-59 0.42
CATH_RAT Ctsh Pro-cathepsin H 8.037e-59 0.35
BXA1_CLOBH botA Botulinum neurotoxin type A 5.451e-58 0.40
NTR2_HUMAN NTSR2 Neurotensin receptor type 2 2.691e-57 0.36
CHIA_SERMA chiA Chitinase A 2.854e-57 0.32
Q8I6Z5_PLAF7 Plasmepsin V 3.78e-57 0.32
NK1R_CAVPO TACR1 Substance-P receptor 1.705e-56 0.46
CATK_HUMAN CTSK Cathepsin K 4.464e-56 0.43
CATJ_RAT Ctsj Cathepsin J 5.893e-56 0.35
KLK8_HUMAN KLK8 Kallikrein-8 1.451e-55 0.33
MBOA4_HUMAN MBOAT4 Ghrelin O-acyltransferase 7.705e-55 0.30
CANX_CHICK Calpain-1 catalytic subunit 1.004e-54 0.44
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 1.976e-54 0.41
Q95PM0_TRYBR rhodesain Cysteine protease 4.775e-54 0.41
Q4U254_9ENTO protease Protease 4.958e-54 0.42
NK2R_RAT Tacr2 Substance-K receptor 2.231e-53 0.46
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 2.309e-53 0.43
AMPB_MOUSE Rnpep Aminopeptidase B 4.375e-53 0.42
AMPL_BOVIN LAP3 Cytosol aminopeptidase 4.375e-53 0.42
TPH1_HUMAN TPH1 Tryptophan 5-hydroxylase 1 3.753e-52 0.33
MMP9_RAT Mmp9 Matrix metalloproteinase-9 4.328e-52 0.37
MYLK_CHICK Mylk Myosin light chain kinase, smooth muscle 2.148e-51 0.40
KLK4_HUMAN KLK4 Kallikrein-4 5.582e-51 0.33
CATZ_RAT Ctsz Cathepsin Z 1.328e-50 0.35
MMP1_HUMAN MMP1 Interstitial collagenase 1.458e-50 0.50
NEP_PIG MME Neprilysin 1.254e-49 0.35
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 1.497e-49 0.48
PSB6_YEAST PRE7 Proteasome subunit beta type-6 1.721e-49 0.39
ACE_RAT Ace Angiotensin-converting enzyme 2.101e-49 0.42
BLA1_STEMA Metallo-beta-lactamase L1 type 3 2.35e-49 0.32
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 6.845e-49 0.44
Q99P97_RAT Histone deacetylase 6 7.227e-49 0.39
CATL1_BOVIN CTSL Cathepsin L1 3.695e-48 0.43
HDAC1_RAT Hdac1 Histone deacetylase 1 4.039e-48 0.34
OPRX_MOUSE Oprl1 Nociceptin receptor 1.574e-47 0.38
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 1.691e-47 0.42
GRIA1_HUMAN GRIA1 Glutamate receptor 1 4.7e-47 0.41
CATL1_RAT Ctsl Cathepsin L1 5.393e-47 0.34
CATC_RAT Ctsc Dipeptidyl peptidase 1 1.7e-46 0.35
POLG_HRV14 Genome polyprotein 1.924e-46 0.37
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 3.585e-46 0.47
PCSK6_HUMAN PCSK6 Proprotein convertase subtilisin/kexin type 6 4.091e-46 0.37
Q6IE76_BOVIN FDFT1 FDFT1 protein 9.43e-46 0.36
MMP2_HUMAN MMP2 72 kDa type IV collagenase 1.382e-45 0.46
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 1.544e-45 0.36
PSB5_YEAST PRE2 Proteasome subunit beta type-5 4.37e-44 0.39
MMP8_HUMAN MMP8 Neutrophil collagenase 4.504e-44 0.42
SSR2_MOUSE Sstr2 Somatostatin receptor type 2 5.903e-44 0.29
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 9.095e-44 0.45
KLK1_HUMAN KLK1 Kallikrein-1 1.124e-43 0.39
KLKB1_HUMAN KLKB1 Plasma kallikrein 1.268e-43 0.39
SYL_STAA8 leuS Leucine--tRNA ligase 1.353e-43 0.35
SSPA_STAAU sspA Glutamyl endopeptidase 2.437e-43 0.35
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 2.476e-43 0.42
CBPB2_HUMAN CPB2 Carboxypeptidase B2 3.742e-43 0.48
CASP1_HUMAN CASP1 Caspase-1 4.111e-43 0.40
SPLB_STAAU splB Serine protease SplB 1.283e-42 0.34
IL1RA_MOUSE Il1rn Interleukin-1 receptor antagonist protein 5.166e-42 0.33
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.176e-41 0.44
AMPB_HUMAN RNPEP Aminopeptidase B 1.333e-41 0.47
TIMP3_RAT Timp3 Metalloproteinase inhibitor 3 1.999e-41 0.35
GLT_PYRHO Glutamate transporter homolog 3.568e-41 0.33
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 5.723e-41 0.38
CAN2_PIG CAPN2 Calpain-2 catalytic subunit 7.542e-41 0.40
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 1.257e-40 0.34
Q8ILP4_PLAF7 Pantothenate kinase, putative 1.28e-40 0.32
PLMN_BOVIN PLG Plasminogen 1.336e-40 0.35
CBX5_HUMAN CBX5 Chromobox protein homolog 5 2.281e-40 0.32
TRYB1_RAT Tpsab1 Tryptase 2.281e-40 0.32
TRYT_CANLF Tryptase 2.281e-40 0.32
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 4.089e-40 0.33
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.023e-39 0.44
AMPN_RAT Anpep Aminopeptidase N 7.528e-39 0.31
PEPA_PIG PGA Pepsin A 7.734e-39 0.40
PP2AA_BOVIN PPP2CA Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 1.169e-38 0.29
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 2.569e-38 0.42
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 4.426e-38 0.38
SCAF_HHV11 UL26 Capsid scaffolding protein 6.374e-38 0.32
CBX2_HUMAN CBX2 Chromobox protein homolog 2 6.694e-38 0.30
CBX6_HUMAN CBX6 Chromobox protein homolog 6 6.694e-38 0.30
CDY1_HUMAN CDY1; CDY1B Testis-specific chromodomain protein Y 1 6.694e-38 0.30
CDYL_HUMAN CDYL Chromodomain Y-like protein 6.694e-38 0.30
GPR88_MOUSE Gpr88 Probable G-protein coupled receptor 88 1.627e-37 0.30
GSP_CRIFA GSP Glutathionylspermidine synthase 2.473e-37 0.36
NTR1_RAT Ntsr1 Neurotensin receptor type 1 3.552e-37 0.34
NK3R_CAVPO TACR3 Neuromedin-K receptor 3.64e-37 0.37
KLK2_HUMAN KLK2 Kallikrein-2 4.297e-37 0.33
TPP2_HUMAN TPP2 Tripeptidyl-peptidase 2 5.953e-37 0.29
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 7.525e-37 0.32
MURI_LACFE murI Glutamate racemase 8.858e-37 0.29
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 1.06e-36 0.35
SSR5_RAT Sstr5 Somatostatin receptor type 5 3.651e-36 0.29
ACER2_HUMAN ACER2 Alkaline ceramidase 2 3.875e-36 0.29
G1FEK8_9CALI Protease 6.395e-36 0.28
I1U3K2_9CALI POL Nonstructural polyprotein 6.395e-36 0.28
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.304e-35 0.53
Q3HTL5_PLAFA fp2B Falcipain 2B 4.357e-35 0.44
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 4.483e-35 0.42
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 7.585e-35 0.32
OPRD_HUMAN OPRD1 Delta-type opioid receptor 1.084e-34 0.45
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 3.081e-34 0.43
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 5.012e-34 0.43
DPO1_THEAQ polA DNA polymerase I, thermostable 5.047e-34 0.42
CATG_HUMAN CTSG Cathepsin G 6.664e-34 0.40
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 9.319e-34 0.39
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 1.529e-33 0.46
RENI_HUMAN REN Renin 2.506e-33 0.37
MC5R_MOUSE Mc5r Melanocortin receptor 5 1.882e-32 0.33
MMP11_HUMAN MMP11 Stromelysin-3 3.77e-32 0.32
CASP9_HUMAN CASP9 Caspase-9 8.102e-32 0.37
Q9NBD4_PLAFA Cysteine protease falcipain-2 1.013e-31 0.39
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 1.256e-31 0.42
CATH_HUMAN CTSH Pro-cathepsin H 3.188e-31 0.40
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 3.288e-31 0.37
KLK5_HUMAN KLK5 Kallikrein-5 3.412e-31 0.33
CATS_HUMAN CTSS Cathepsin S 6.011e-31 0.48
PEPA1_PENJA Penicillopepsin-1 7.008e-31 0.37
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 3.865e-30 0.35
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 1.012e-29 0.39
ECE1_RAT Ece1 Endothelin-converting enzyme 1 1.145e-29 0.35
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 5.691e-29 0.39
CATD_HUMAN CTSD Cathepsin D 7.093e-29 0.38
ELAS_PSEAE lasB Elastase 1.767e-28 0.37
CASPA_HUMAN CASP10 Caspase-10 2.273e-28 0.29
NK3R_RAT Tacr3 Neuromedin-K receptor 3.612e-28 0.46
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 5.17e-28 0.44
SYL_ECOLI leuS Leucine--tRNA ligase 5.179e-28 0.35
DPP2_HUMAN DPP7 Dipeptidyl peptidase 2 6.362e-28 0.47
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 1.681e-27 0.50
CMA1_HUMAN CMA1 Chymase 1.817e-27 0.41
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 2.345e-27 0.33
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 2.345e-27 0.33
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 3.731e-27 0.35
CSK_HUMAN CSK Tyrosine-protein kinase CSK 3.864e-27 0.37
CBPA1_BOVIN CPA1 Carboxypeptidase A1 5.172e-27 0.45
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 7.037e-27 0.38
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 1.301e-26 0.43
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 1.569e-26 0.39
O68720_YERPE yopH Targeted effector protein 6.745e-26 0.34
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 1.193e-25 0.33
NAAA_HUMAN NAAA N-acylethanolamine-hydrolyzing acid amidase 1.305e-25 0.36
CTRA_BOVIN Chymotrypsinogen A 1.749e-25 0.37
FNTB_RAT Fntb Protein farnesyltransferase subunit beta 2.034e-25 0.52
FNTA_RAT Fnta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 3.208e-25 0.52
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 3.255e-25 0.41
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 3.702e-25 0.36
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 5.076e-25 0.40
GNPAT_HUMAN GNPAT Dihydroxyacetone phosphate acyltransferase 6.482e-25 0.40
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 7.973e-25 0.30
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 9.105e-25 0.56
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 1.175e-24 0.58
PSB10_HUMAN PSMB10 Proteasome subunit beta type-10 1.249e-24 0.42
MC4R_MOUSE Mc4r Melanocortin receptor 4 2.57e-24 0.33
RIR1_MOUSE Rrm1 Ribonucleoside-diphosphate reductase large subunit 6.243e-24 0.29
CAN1_RAT Capn1 Calpain-1 catalytic subunit 6.794e-24 0.34
CHIB_SERMA chiB Chitinase B 1.075e-23 0.32
A5A4K8_RABIT MLNR Motilin receptor 1.084e-23 0.44
CASP3_HUMAN CASP3 Caspase-3 1.174e-23 0.47
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 1.734e-23 0.42
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 6.089e-23 0.42
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 6.125e-23 0.42
PSA1_HUMAN PSMA1 Proteasome subunit alpha type-1 8.669e-23 0.42
PSA2_HUMAN PSMA2 Proteasome subunit alpha type-2 8.669e-23 0.42
PSA3_HUMAN PSMA3 Proteasome subunit alpha type-3 8.669e-23 0.42
PSA4_HUMAN PSMA4 Proteasome subunit alpha type-4 8.669e-23 0.42
PSA5_HUMAN PSMA5 Proteasome subunit alpha type-5 8.669e-23 0.42
PSA6_HUMAN PSMA6 Proteasome subunit alpha type-6 8.669e-23 0.42
PSA7_HUMAN PSMA7 Proteasome subunit alpha type-7 8.669e-23 0.42
PSB11_HUMAN PSMB11 Proteasome subunit beta type-11 8.669e-23 0.42
PSB3_HUMAN PSMB3 Proteasome subunit beta type-3 8.669e-23 0.42
PSB4_HUMAN PSMB4 Proteasome subunit beta type-4 8.669e-23 0.42
PSB6_HUMAN PSMB6 Proteasome subunit beta type-6 8.669e-23 0.42
PSB7_HUMAN PSMB7 Proteasome subunit beta type-7 8.669e-23 0.42
PSMA8_HUMAN PSMA8 Proteasome subunit alpha-type 8 8.669e-23 0.42
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 9.503e-23 0.42
O31048_PORGN DPP IV Dipeptidyl peptidase IV 1.019e-22 0.43
CBPB1_PIG CPB1 Carboxypeptidase B 1.237e-22 0.40
PEPT1_DERPT DERP1 Peptidase 1 1.742e-22 0.32
TGM2_MOUSE Tgm2 Protein-glutamine gamma-glutamyltransferase 2 4.398e-22 0.35
LY96_HUMAN LY96 Lymphocyte antigen 96 4.553e-22 0.43
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 5.066e-22 0.38
XPP2_RAT Xpnpep2 Xaa-Pro aminopeptidase 2 8.093e-22 0.31
CTRC_HUMAN CTRC Chymotrypsin-C 1.134e-21 0.44
Q9YQ12_9HIV1 protease Protease 1.163e-21 0.46
SCYD_MAGO7 SDH1 Scytalone dehydratase 2.423e-21 0.40
MC3R_HUMAN MC3R Melanocortin receptor 3 2.564e-21 0.41
CATK_RABIT CTSK Cathepsin K 2.595e-21 0.40
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3.27e-21 0.34
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 4.64e-21 0.35
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 6.207e-21 0.46
PAR1_HUMAN F2R Proteinase-activated receptor 1 1.093e-20 0.41
SOAT1_CHLAE SOAT1 Sterol O-acyltransferase 1 1.128e-20 0.33
HIS7_ECOLI hisB Histidine biosynthesis bifunctional protein HisB 1.453e-20 0.29
D5FGE8_TRYCR POT1.5 Putative amino acid permease/transporter 1.475e-20 0.33
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 3.857e-20 0.42
PADI1_HUMAN PADI1 Protein-arginine deiminase type-1 3.88e-20 0.31
PADI3_HUMAN PADI3 Protein-arginine deiminase type-3 3.88e-20 0.31
TRYB1_MOUSE Tpsab1 Tryptase 4.22e-20 0.32
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 1.193e-19 0.31
OPRM_MOUSE Oprm1 Mu-type opioid receptor 1.277e-19 0.39
MMP7_HUMAN MMP7 Matrilysin 1.985e-19 0.36
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.012e-19 0.32
EDNRA_MOUSE Ednra Endothelin-1 receptor 2.396e-19 0.33
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 3.246e-19 0.35
CATD_BOVIN CTSD Cathepsin D 3.401e-19 0.34
HISX_ECOLI hisD Histidinol dehydrogenase 4.11e-19 0.30
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 4.294e-19 0.33
CARP_RHICH Rhizopuspepsin 4.356e-19 0.33
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 5.386e-19 0.35
NK3R_HUMAN TACR3 Neuromedin-K receptor 5.793e-19 0.36
XPP2_HUMAN XPNPEP2 Xaa-Pro aminopeptidase 2 1.281e-18 0.31
Q9ERC0_RAT Npy2r Neuropeptide Y receptor Y2 2.898e-18 0.29
ANF_HUMAN NPPA Natriuretic peptides A 3.606e-18 0.36
NEC2_HUMAN PCSK2 Neuroendocrine convertase 2 3.72e-18 0.29
MMP12_MOUSE Mmp12 Macrophage metalloelastase 4.146e-18 0.29
ECE1_BOVIN ECE1 Endothelin-converting enzyme 1 6.375e-18 0.28
GSTM1_HUMAN GSTM1 Glutathione S-transferase Mu 1 6.556e-18 0.28
OPRM_HUMAN OPRM1 Mu-type opioid receptor 7.46e-18 0.51
Q91H74_9FLAV Genome polyprotein 7.917e-18 0.38
RIR1_MYCTU nrdE Ribonucleoside-diphosphate reductase subunit alpha 8.52e-18 0.28
PRTN3_MOUSE Prtn3 Myeloblastin 9.056e-18 0.28
DPP8_HUMAN DPP8 Dipeptidyl peptidase 8 1.29e-17 0.43
MMP12_HUMAN MMP12 Macrophage metalloelastase 1.451e-17 0.46
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 2.271e-17 0.35
CBPB1_HUMAN CPB1 Carboxypeptidase B 2.511e-17 0.48
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 4.11e-17 0.33
AMPX_VIBPR Bacterial leucyl aminopeptidase 5.404e-17 0.42
DLG4_HUMAN DLG4 Disks large homolog 4 1.11e-16 0.39
O07911_STAAU agrC AgrC 1.11e-16 0.32
PPM1B_HUMAN PPM1B Protein phosphatase 1B 1.11e-16 0.29
RENI_RAT Ren1 Renin 1.11e-16 0.32
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 1.11e-16 0.31
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 1.11e-16 0.41
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 2.22e-16 0.34
FNTA_BOVIN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 3.331e-16 0.40
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 3.331e-16 0.37
GABT_RAT Abat 4-aminobutyrate aminotransferase, mitochondrial 5.551e-16 0.31
SOAT2_CHLAE SOAT2 Sterol O-acyltransferase 2 5.551e-16 0.33
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 8.882e-16 0.32
KYNU_HUMAN KYNU Kynureninase 1.11e-15 0.34
AMPN_MOUSE Anpep Aminopeptidase N 1.998e-15 0.42
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 2.109e-15 0.58
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 2.22e-15 0.31
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.442e-15 0.41
AAAT_HUMAN SLC1A5 Neutral amino acid transporter B(0) 3.442e-15 0.29
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 3.442e-15 0.36
NK2R_HUMAN TACR2 Substance-K receptor 3.553e-15 0.35
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 5.218e-15 0.38
PAR2_HUMAN F2RL1 Proteinase-activated receptor 2 7.661e-15 0.34
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 8.105e-15 0.39
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 8.771e-15 0.41
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 1.21e-14 0.33
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 1.366e-14 0.35
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 1.965e-14 0.39
MDM4_HUMAN MDM4 Protein Mdm4 2.043e-14 0.33
GP142_MOUSE Gpr142 Probable G-protein coupled receptor 142 2.143e-14 0.32
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 2.576e-14 0.38
CASP4_HUMAN CASP4 Caspase-4 3.231e-14 0.29
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 3.342e-14 0.30
XPP1_HUMAN XPNPEP1 Xaa-Pro aminopeptidase 1 4.43e-14 0.31
HDAC1_HUMAN HDAC1 Histone deacetylase 1 5.662e-14 0.40
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 5.751e-14 0.32
MC3R_MOUSE Mc3r Melanocortin receptor 3 6.917e-14 0.33
PLMN_RAT Plg Plasminogen 7.039e-14 0.53
HDAC2_HUMAN HDAC2 Histone deacetylase 2 7.283e-14 0.36
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 9.193e-14 0.38
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 9.504e-14 0.30
Q6PRC7_IXORI Legumain-like protease 1.159e-13 0.31
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 1.416e-13 0.31
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.69e-13 0.37
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 2.173e-13 0.29
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 2.178e-13 0.33
PGTB1_BOVIN PGGT1B Geranylgeranyl transferase type-1 subunit beta 2.663e-13 0.36
PCSK7_HUMAN PCSK7 Proprotein convertase subtilisin/kexin type 7 3.23e-13 0.29
GSTP1_HUMAN GSTP1 Glutathione S-transferase P 3.932e-13 0.33
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 5.125e-13 0.28
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 5.518e-13 0.37
MAP2_HUMAN METAP2 Methionine aminopeptidase 2 5.599e-13 0.39
HEPS_HUMAN HPN Serine protease hepsin 5.733e-13 0.37
Q9JN24_ECOLX def Peptide deformylase 1.046e-12 0.35
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 1.134e-12 0.30
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 1.134e-12 0.30
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 1.134e-12 0.30
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 1.134e-12 0.30
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 1.134e-12 0.30
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 1.134e-12 0.30
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 1.134e-12 0.30
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 1.134e-12 0.30
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 1.134e-12 0.30
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 1.134e-12 0.30
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 1.134e-12 0.30
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 1.134e-12 0.30
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 1.134e-12 0.30
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 1.134e-12 0.30
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 1.134e-12 0.30
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 1.134e-12 0.30
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 1.134e-12 0.30
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 1.134e-12 0.30
MC4R_HUMAN MC4R Melanocortin receptor 4 1.454e-12 0.41
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 1.659e-12 0.33
THRB_HUMAN F2 Prothrombin 1.842e-12 0.43
PEPD_HUMAN PEPD Xaa-Pro dipeptidase 2.757e-12 0.30
TYRO_HUMAN TYR Tyrosinase 2.81e-12 0.31
NMBR_HUMAN NMBR Neuromedin-B receptor 3.251e-12 0.37
CATC_HUMAN CTSC Dipeptidyl peptidase 1 3.563e-12 0.46
B3DH72_DANRE oprd1b Opioid receptor, delta 1b 3.82e-12 0.30
O57585_DANRE oprd1a Opioid receptor homologue 3.82e-12 0.30
GPR88_HUMAN GPR88 Probable G-protein coupled receptor 88 4.657e-12 0.33
UROK_HUMAN PLAU Urokinase-type plasminogen activator 4.941e-12 0.34
ELNE_HUMAN ELANE Neutrophil elastase 5.781e-12 0.35
FNTB_BOVIN FNTB Protein farnesyltransferase subunit beta 1.399e-11 0.40
ELNE_MOUSE Elane Neutrophil elastase 1.437e-11 0.28
DPP9_HUMAN DPP9 Dipeptidyl peptidase 9 1.458e-11 0.43
PLM1_PLAFA Plasmepsin-1 2.897e-11 0.32
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 4.573e-11 0.37
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 4.757e-11 0.30
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 5.709e-11 0.46
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 7.119e-11 0.31
CCNA2_HUMAN CCNA2 Cyclin-A2 7.182e-11 0.44
CASP7_HUMAN CASP7 Caspase-7 7.29e-11 0.37
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 7.56e-11 0.41
HDAC8_HUMAN HDAC8 Histone deacetylase 8 8.639e-11 0.36
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 1.005e-10 0.31
CASP8_HUMAN CASP8 Caspase-8 1.098e-10 0.40
CASP1_MOUSE Casp1 Caspase-1 1.104e-10 0.40
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 1.137e-10 0.40
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.003e-10 0.31
SORT_HUMAN SORT1 Sortilin 2.07e-10 0.29
FPRS1_MOUSE Fpr-s1 Formyl peptide receptor-related sequence 1 2.072e-10 0.42
NOS3_BOVIN NOS3 Nitric oxide synthase, endothelial 2.284e-10 0.39
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 2.317e-10 0.30
PADI2_HUMAN PADI2 Protein-arginine deiminase type-2 2.659e-10 0.30
SYLC_HUMAN LARS1 Leucine--tRNA ligase, cytoplasmic 2.921e-10 0.35
BIRC2_HUMAN BIRC2 Baculoviral IAP repeat-containing protein 2 3.128e-10 0.41
IDE_HUMAN IDE Insulin-degrading enzyme 3.207e-10 0.32
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 4.036e-10 0.31
PAO1_MAIZE MPAO1 Polyamine oxidase 1 4.175e-10 0.29
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 4.229e-10 0.37
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 4.597e-10 0.31
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 4.884e-10 0.29
TAT_HV1H2 tat Protein Tat 5.076e-10 0.29
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 5.213e-10 0.41
Q9Z1J7_RAT Slc1a5 Amino acid transporter 6.439e-10 0.29
EDNRB_RAT Ednrb Endothelin receptor type B 6.611e-10 0.33
BKRB1_RAT Bdkrb1 B1 bradykinin receptor 7.379e-10 0.36
Q6DMN0_TOXGO CPL Cathepsin L 7.541e-10 0.29
TPH1_RAT Tph1 Tryptophan 5-hydroxylase 1 7.541e-10 0.29
BACE1_HUMAN BACE1 Beta-secretase 1 7.688e-10 0.39
SPP2A_HUMAN SPPL2A Signal peptide peptidase-like 2A 7.959e-10 0.39
PEPC_HUMAN PGC Gastricsin 1.147e-09 0.30
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.378e-09 0.38
NOS1_RAT Nos1 Nitric oxide synthase, brain 1.485e-09 0.39
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 1.588e-09 0.43
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 1.592e-09 0.32
HDAC6_MOUSE Hdac6 Histone deacetylase 6 1.748e-09 0.38
RASH_HUMAN HRAS GTPase HRas 2.218e-09 0.35
OPRX_HUMAN OPRL1 Nociceptin receptor 2.269e-09 0.47
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 2.676e-09 0.34
PLMN_HUMAN PLG Plasminogen 2.963e-09 0.36
PPCE_BOVIN PREP Prolyl endopeptidase 3.108e-09 0.29
O90781_9PLVG HIV-1 protease HIV-1 protease 3.313e-09 0.30
HISX_BRUSU hisD Histidinol dehydrogenase 4.561e-09 0.30
P2RX4_RAT P2rx4 P2X purinoceptor 4 4.765e-09 0.30
FNTA_HUMAN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 6.219e-09 0.43
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 6.234e-09 0.42
PLM2_PLAFA Plasmepsin-2 6.895e-09 0.33
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 7.212e-09 0.30
KLK7_HUMAN KLK7 Kallikrein-7 7.676e-09 0.33
CYSK_MYCTU cysK1 O-acetylserine sulfhydrylase 8.387e-09 0.40
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 9.449e-09 0.39
LGMN_HUMAN LGMN Legumain 9.952e-09 0.32
TPP2_RAT Tpp2 Tripeptidyl-peptidase 2 1.068e-08 0.35
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 1.128e-08 0.35
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 1.319e-08 0.36
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 1.523e-08 0.44
TERT_HUMAN TERT Telomerase reverse transcriptase 2.18e-08 0.42
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 2.827e-08 0.31
ITB3_HUMAN ITGB3 Integrin beta-3 2.906e-08 0.46
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 3.717e-08 0.29
HISX_BRAOC HDH Histidinol dehydrogenase, chloroplastic 3.793e-08 0.30
CATK_RAT Ctsk Cathepsin K 4.69e-08 0.29
LEF_BACAN lef Lethal factor 5.597e-08 0.32
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 5.605e-08 0.38
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 6.846e-08 0.42
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 7.036e-08 0.48
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 7.262e-08 0.32
OPRX_CAVPO OPRL1 Nociceptin receptor 8.826e-08 0.36
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 9.862e-08 0.30
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 1.009e-07 0.30
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 1.053e-07 0.30
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.162e-07 0.28
DCOR_HUMAN ODC1 Ornithine decarboxylase 1.227e-07 0.28
CCKAR_RAT Cckar Cholecystokinin receptor type A 1.612e-07 0.37
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.769e-07 0.41
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.794e-07 0.31
BLA2_BACCE blm Metallo-beta-lactamase type 2 1.98e-07 0.37
UR2R_HUMAN UTS2R Urotensin-2 receptor 2.213e-07 0.40
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 2.215e-07 0.33
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 2.483e-07 0.33
MMP13_RAT Mmp13 Collagenase 3 2.68e-07 0.28
TRY1_BOVIN Cationic trypsin 2.737e-07 0.37
MMP13_HUMAN MMP13 Collagenase 3 2.985e-07 0.37
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 3.134e-07 0.31
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 3.335e-07 0.29
POLG_HCV1 Genome polyprotein 3.469e-07 0.37
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 3.628e-07 0.34
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 3.645e-07 0.36
TRY1_HUMAN PRSS1 Trypsin-1 3.75e-07 0.34
MMP10_HUMAN MMP10 Stromelysin-2 3.785e-07 0.37
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 4.388e-07 0.35
MAP11_HUMAN METAP1 Methionine aminopeptidase 1 5.324e-07 0.32
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 6.575e-07 0.34
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 1.129e-06 0.35
DPP4_HUMAN DPP4 Dipeptidyl peptidase 4 1.232e-06 0.48
ALBU_BOVIN ALB Serum albumin 1.277e-06 0.29
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.33e-06 0.41
PEN2_HUMAN PSENEN Gamma-secretase subunit PEN-2 1.358e-06 0.39
GHSR_RAT Ghsr Growth hormone secretagogue receptor type 1 1.428e-06 0.40
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 1.726e-06 0.36
AMPD2_HUMAN AMPD2 AMP deaminase 2 1.959e-06 0.29
PGH2_BOVIN PTGS2 Prostaglandin G/H synthase 2 2.185e-06 0.29
F13A_HUMAN F13A1 Coagulation factor XIII A chain 2.25e-06 0.33
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 2.294e-06 0.30
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 2.443e-06 0.34
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 2.649e-06 0.31
APH1A_HUMAN APH1A Gamma-secretase subunit APH-1A 2.76e-06 0.39
APH1B_HUMAN APH1B Gamma-secretase subunit APH-1B 2.76e-06 0.39
NICA_HUMAN NCSTN Nicastrin 2.76e-06 0.39
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 2.807e-06 0.33
PSN2_HUMAN PSEN2 Presenilin-2 2.83e-06 0.39
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 2.95e-06 0.32
UR2R_RAT Uts2r Urotensin-2 receptor 3.038e-06 0.38
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 3.203e-06 0.29
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 3.349e-06 0.29
R1AB_SARS rep Replicase polyprotein 1ab 3.51e-06 0.32
GRIA4_RAT Gria4 Glutamate receptor 4 3.596e-06 0.33
NOS1_MOUSE Nos1 Nitric oxide synthase, brain 3.933e-06 0.30
PSN1_HUMAN PSEN1 Presenilin-1 5.036e-06 0.39
WDR5_HUMAN WDR5 WD repeat-containing protein 5 5.736e-06 0.33
GP142_HUMAN GPR142 Probable G-protein coupled receptor 142 5.805e-06 0.32
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 5.941e-06 0.35
CASP6_HUMAN CASP6 Caspase-6 5.985e-06 0.37
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 7.356e-06 0.31
IKBA_HUMAN NFKBIA NF-kappa-B inhibitor alpha 7.639e-06 0.39
ACACA_RAT Acaca Acetyl-CoA carboxylase 1 9.128e-06 0.35
FAS_HUMAN FASN Fatty acid synthase 9.652e-06 0.33

Rifapentine

POL_WMSV pol Gag-Pol polyprotein 1.36e-182 0.72
RPOB_MYCTU rpoB DNA-directed RNA polymerase subunit beta 5.42e-161 0.87
DPOLB_MOUSE Polb DNA polymerase beta 1.784e-109 0.61
SO1B3_HUMAN SLCO1B3 Solute carrier organic anion transporter family member 1B3 9.719e-94 0.87
SO2B1_HUMAN SLCO2B1 Solute carrier organic anion transporter family member 2B1 2.389e-84 0.68
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 2.405e-67 0.87
ABCBB_RAT Abcb11 Bile salt export pump 1.098e-26 0.68
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.221e-15 0.68
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 7.727e-14 0.68
NR1I2_HUMAN NR1I2 Nuclear receptor subfamily 1 group I member 2 6.86e-08 0.87

Estramustine

STS_HUMAN STS Steryl-sulfatase 5.361e-150 0.63
Q95MF8_PIG Sulfotransferase 3.247e-87 0.50
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.319e-76 0.65
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 2.3e-65 0.49
SHBG_HUMAN SHBG Sex hormone-binding globulin 2.582e-57 0.59
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 2.589e-49 0.52
ST1E1_BOVIN SULT1E1 Sulfotransferase 1E1 1.991e-48 0.32
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.712e-45 0.59
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 5.577e-40 0.50
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 9.763e-38 0.43
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 5.858e-37 0.59
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.533e-36 0.59
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 2.402e-36 0.59
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 1.196e-31 0.33
S22A8_RAT Slc22a8 Solute carrier family 22 member 8 9.435e-29 0.46
ESR1_HUMAN ESR1 Estrogen receptor 5.593e-26 0.59
SHBG_RAT Shbg Sex hormone-binding globulin 7.184e-26 0.32
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 1.678e-23 0.59
ESR2_HUMAN ESR2 Estrogen receptor beta 8.178e-23 0.59
Q690N0_BOVIN PGR Progesterone receptor 1.477e-19 0.59
CP19A_HUMAN CYP19A1 Aromatase 3.053e-19 0.52
ANDR_RAT Ar Androgen receptor 5.809e-19 0.59
ERR1_HUMAN ESRRA Steroid hormone receptor ERR1 1.161e-18 0.59
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 1.457e-18 0.30
ESR1_MOUSE Esr1 Estrogen receptor 3.406e-18 0.59
ESR2_MOUSE Esr2 Estrogen receptor beta 3.406e-18 0.59
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 4.706e-18 0.46
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 1.11e-16 0.51
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 2.22e-16 0.30
ESR1_RAT Esr1 Estrogen receptor 3.331e-15 0.59
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 5.629e-14 0.35
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.162e-12 0.59
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 4.417e-11 0.33
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 8.218e-11 0.34
ANDR_HUMAN AR Androgen receptor 7.35e-10 0.59
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.301e-08 0.59
DGLA_MOUSE Dagla Sn1-specific diacylglycerol lipase alpha 4.863e-08 0.28
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 1.211e-07 0.30
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 2.133e-07 0.65
ESR2_RAT Esr2 Estrogen receptor beta 4.082e-07 0.59
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 6.882e-07 0.59
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 7.2e-07 0.30
TAT_HV112 tat Protein Tat 1.827e-06 0.28
GCR_MOUSE Nr3c1 Glucocorticoid receptor 4.148e-06 0.33
AMPC_ECOLI ampC Beta-lactamase 7.324e-06 0.49
ANDR_MOUSE Ar Androgen receptor 9.042e-06 0.34

Encainide

FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.976e-131 0.36
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 3.219e-117 0.41
KCNQ1_HUMAN KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 1.462e-106 0.38
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 1.076e-87 0.39
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 4.453e-80 0.39
FABH_STRP3 fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 9.683e-65 0.33
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 9.782e-64 0.43
LDLR_HUMAN LDLR Low-density lipoprotein receptor 7.976e-63 0.37
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.113e-57 0.38
BRPF1_HUMAN BRPF1 Peregrin 1.589e-54 0.44
CLTR2_HUMAN CYSLTR2 Cysteinyl leukotriene receptor 2 2.169e-54 0.34
RCOR1_HUMAN RCOR1 REST corepressor 1 1.291e-52 0.36
FABH_STAAM fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 5.168e-52 0.33
DRD5_RAT Drd5 D(1B) dopamine receptor 1.525e-49 0.33
A5H660_SCHMA HDAC8 Histone deacetylase 8 9.14e-49 0.38
GIP_HUMAN GIP Gastric inhibitory polypeptide 2.352e-48 0.33
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 3.887e-48 0.34
Q4DCQ3_TRYCC Superoxide dismutase 5.846e-48 0.31
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 1.067e-47 0.44
SCAF_HHV8P ORF17 Capsid scaffolding protein 6.652e-46 0.36
HDAC1_HUMAN HDAC1 Histone deacetylase 1 8.433e-45 0.48
MIP_LEGPN mip Outer membrane protein MIP 1.284e-44 0.32
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 2.734e-44 0.34
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.815e-43 0.42
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 3.67e-41 0.38
MTR1B_CHICK Melatonin receptor type 1B 2.065e-40 0.32
FABH_HAEIN fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 3.171e-40 0.32
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 3.884e-40 0.36
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 1.17e-38 0.34
Q76NL8_PLAF7 Falcilysin 9.681e-38 0.30
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 4.659e-37 0.44
DRD2_CANLF DRD2 D(2) dopamine receptor 1.332e-36 0.29
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 2.429e-36 0.43
GHSR_RABIT GHSR Growth hormone secretagogue receptor type 1 9.362e-36 0.28
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 1.167e-35 0.35
KDM1B_HUMAN KDM1B Lysine-specific histone demethylase 1B 1.195e-35 0.29
DRD3_RAT Drd3 D(3) dopamine receptor 1.266e-35 0.33
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 4.124e-35 0.36
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.872e-34 0.42
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 8.305e-34 0.31
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.627e-33 0.41
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 5.864e-32 0.34
AOC3_MOUSE Aoc3 Membrane primary amine oxidase 2.103e-31 0.31
MRGX1_HUMAN MRGPRX1 Mas-related G-protein coupled receptor member X1 3.224e-31 0.33
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 5.543e-31 0.33
5HT1B_GORGO HTR1B 5-hydroxytryptamine receptor 1B 6.282e-31 0.31
CLTR1_HUMAN CYSLTR1 Cysteinyl leukotriene receptor 1 1.536e-30 0.34
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 3.216e-30 0.33
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 8e-30 0.37
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 1.398e-29 0.33
HDAC2_HUMAN HDAC2 Histone deacetylase 2 1.105e-27 0.48
DEF_PSEAE def Peptide deformylase 1.704e-27 0.30
PPME1_HUMAN PPME1 Protein phosphatase methylesterase 1 2.077e-27 0.34
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 2.165e-27 0.35
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.516e-26 0.39
MBTP1_HUMAN MBTPS1 Membrane-bound transcription factor site-1 protease 4.074e-26 0.31
FTSZ_MYCTU ftsZ Cell division protein FtsZ 5.827e-26 0.32
MMP1_HUMAN MMP1 Interstitial collagenase 1.033e-25 0.35
Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 1.297e-25 0.39
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 3.08e-25 0.32
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 5.558e-25 0.33
FA10_HUMAN F10 Coagulation factor X 7.324e-25 0.53
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 1.883e-24 0.39
PRIO_SHEEP PRNP Major prion protein 4.767e-24 0.33
MMP13_HUMAN MMP13 Collagenase 3 7.136e-24 0.36
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.71e-23 0.37
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.919e-23 0.42
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 2.847e-23 0.29
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 3.236e-23 0.36
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 4.406e-23 0.34
CATZ_RAT Ctsz Cathepsin Z 5.518e-23 0.28
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 6.393e-23 0.37
MMP7_HUMAN MMP7 Matrilysin 1.949e-22 0.35
PRTN3_HUMAN PRTN3 Myeloblastin 4.514e-22 0.36
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 5.367e-22 0.36
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 6.39e-22 0.39
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 9.839e-22 0.33
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 9.952e-22 0.34
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 1.089e-21 0.32
MMP3_HUMAN MMP3 Stromelysin-1 1.457e-21 0.35
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 4.629e-21 0.33
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 8.922e-21 0.36
TGM2_MOUSE Tgm2 Protein-glutamine gamma-glutamyltransferase 2 1.194e-20 0.33
ADAM9_HUMAN ADAM9 Disintegrin and metalloproteinase domain-containing protein 9 1.38e-20 0.32
ITA4_HUMAN ITGA4 Integrin alpha-4 2.093e-20 0.36
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 2.111e-20 0.33
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 2.113e-20 0.39
GP183_MOUSE Gpr183 G-protein coupled receptor 183 4.806e-20 0.31
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.522e-19 0.48
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.644e-19 0.37
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 3.664e-19 0.37
MECP2_HUMAN MECP2 Methyl-CpG-binding protein 2 4.43e-19 0.30
DRD2_RAT Drd2 D(2) dopamine receptor 5.005e-19 0.36
HDAC8_HUMAN HDAC8 Histone deacetylase 8 5.177e-19 0.38
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 5.756e-19 0.29
HRH3_RAT Hrh3 Histamine H3 receptor 5.817e-19 0.34
KCNQ4_HUMAN KCNQ4 Potassium voltage-gated channel subfamily KQT member 4 8.29e-19 0.30
NR1H4_HUMAN NR1H4 Bile acid receptor 1.371e-18 0.40
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 2.663e-18 0.37
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 3.581e-18 0.42
AUKBA_XENLA aurkb-a Aurora kinase B-A 3.886e-18 0.29
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 4.76e-18 0.36
HRH3_HUMAN HRH3 Histamine H3 receptor 6.132e-18 0.42
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 7.138e-18 0.38
CATH_RAT Ctsh Pro-cathepsin H 8.104e-18 0.28
CATJ_RAT Ctsj Cathepsin J 8.104e-18 0.28
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.145e-17 0.38
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.236e-17 0.39
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 1.568e-17 0.37
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.744e-17 0.36
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 3.463e-17 0.37
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 3.71e-17 0.37
DRD4_RAT Drd4 D(4) dopamine receptor 1.11e-16 0.35
GPR35_HUMAN GPR35 G-protein coupled receptor 35 1.11e-16 0.44
Q5TKS5_STAAU fabI Enoyl-ACP reductase 1.11e-16 0.39
SENP7_HUMAN SENP7 Sentrin-specific protease 7 1.11e-16 0.40
STXA_SHIDY stxA Shiga toxin subunit A 1.11e-16 0.32
ACHA3_HUMAN CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 2.22e-16 0.39
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 3.331e-16 0.41
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 3.331e-16 0.41
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 4.441e-16 0.39
CASR_RAT Casr Extracellular calcium-sensing receptor 4.441e-16 0.35
Q38C41_TRYB2 Phosphotransferase 4.441e-16 0.39
LUCI_PHOPY Luciferin 4-monooxygenase 5.551e-16 0.42
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5.551e-16 0.38
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 8.882e-16 0.40
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 8.882e-16 0.30
Q9JKC1_RAT Bche Carboxylic ester hydrolase 8.882e-16 0.31
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 9.992e-16 0.30
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 9.992e-16 0.38
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 1.221e-15 0.30
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.443e-15 0.38
ABHD6_HUMAN ABHD6 Monoacylglycerol lipase ABHD6 1.776e-15 0.34
Q70GC6_9HEPC NS5B RNA-directed RNA polymerase 2.22e-15 0.35
BRD1_HUMAN BRD1 Bromodomain-containing protein 1 3.664e-15 0.37
ACES_MOUSE Ache Acetylcholinesterase 4.663e-15 0.42
CATC_RAT Ctsc Dipeptidyl peptidase 1 6.772e-15 0.28
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 7.216e-15 0.35
DRD3_HUMAN DRD3 D(3) dopamine receptor 7.438e-15 0.37
CATS_HUMAN CTSS Cathepsin S 1.388e-14 0.39
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 1.477e-14 0.40
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.577e-14 0.37
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 1.721e-14 0.34
AA3R_HUMAN ADORA3 Adenosine receptor A3 2.121e-14 0.39
MMP13_RAT Mmp13 Collagenase 3 2.32e-14 0.31
MK03_MOUSE Mapk3 Mitogen-activated protein kinase 3 2.343e-14 0.32
CATL1_HUMAN CTSL Cathepsin L1 2.587e-14 0.37
ROCK2_RAT Rock2 Rho-associated protein kinase 2 3.042e-14 0.29
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 4.496e-14 0.37
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 5.418e-14 0.40
MMP12_HUMAN MMP12 Macrophage metalloelastase 5.54e-14 0.36
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 7.516e-14 0.41
SL9A1_RAT Slc9a1 Sodium/hydrogen exchanger 1 8.094e-14 0.35
SC5A7_HUMAN SLC5A7 High affinity choline transporter 1 8.582e-14 0.30
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 9.659e-14 0.42
HDAC6_HUMAN HDAC6 Histone deacetylase 6 9.825e-14 0.38
ACHB2_RAT Chrnb2 Neuronal acetylcholine receptor subunit beta-2 1.377e-13 0.39
AREG_HUMAN AREG Amphiregulin 1.842e-13 0.29
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 2.345e-13 0.30
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 2.518e-13 0.35
CNR1_RAT Cnr1 Cannabinoid receptor 1 2.542e-13 0.45
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 2.628e-13 0.41
ACHA4_RAT Chrna4 Neuronal acetylcholine receptor subunit alpha-4 3.004e-13 0.39
FAK1_HUMAN PTK2 Focal adhesion kinase 1 3.241e-13 0.37
GLMU_STRPN glmU Bifunctional protein GlmU 3.922e-13 0.29
V1AR_RAT Avpr1a Vasopressin V1a receptor 7.301e-13 0.41
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 8.146e-13 0.39
GRM3_HUMAN GRM3 Metabotropic glutamate receptor 3 9.039e-13 0.35
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 1.01e-12 0.37
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.145e-12 0.39
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.197e-12 0.36
TAAR1_RAT Taar1 Trace amine-associated receptor 1 1.426e-12 0.38
GRM3_RAT Grm3 Metabotropic glutamate receptor 3 1.493e-12 0.35
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.694e-12 0.35
AURKA_HUMAN AURKA Aurora kinase A 2.125e-12 0.38
OX1R_HUMAN HCRTR1 Orexin receptor type 1 3.44e-12 0.39
TTK_HUMAN TTK Dual specificity protein kinase TTK 3.601e-12 0.36
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 3.758e-12 0.32
QRFPR_HUMAN QRFPR Pyroglutamylated RF-amide peptide receptor 4.123e-12 0.34
CLTR1_CAVPO CYSLTR1 Cysteinyl leukotriene receptor 1 4.369e-12 0.30
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 4.393e-12 0.35
SCNNA_MOUSE Scnn1a Amiloride-sensitive sodium channel subunit alpha 4.628e-12 0.29
MMP8_HUMAN MMP8 Neutrophil collagenase 4.671e-12 0.36
BRDT_HUMAN BRDT Bromodomain testis-specific protein 4.699e-12 0.29
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 5.209e-12 0.37
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 7.697e-12 0.39
MMP2_HUMAN MMP2 72 kDa type IV collagenase 8.895e-12 0.36
SENP1_HUMAN SENP1 Sentrin-specific protease 1 9.016e-12 0.29
SUV91_HUMAN SUV39H1 Histone-lysine N-methyltransferase SUV39H1 9.095e-12 0.32
GLI1_MOUSE Gli1 Zinc finger protein GLI1 1.011e-11 0.37
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 1.011e-11 0.40
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 1.19e-11 0.39
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.22e-11 0.37
TKNK_HUMAN TAC3 Tachykinin-3 1.537e-11 0.28
SHH_MOUSE Shh Sonic hedgehog protein 1.56e-11 0.39
ACES_RAT Ache Acetylcholinesterase 1.58e-11 0.39
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 1.754e-11 0.31
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 1.778e-11 0.36
MK01_MOUSE Mapk1 Mitogen-activated protein kinase 1 2.113e-11 0.37
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 2.203e-11 0.33
UROK_HUMAN PLAU Urokinase-type plasminogen activator 2.326e-11 0.40
CHLE_HUMAN BCHE Cholinesterase 3.353e-11 0.35
V2R_RAT Avpr2 Vasopressin V2 receptor 3.408e-11 0.41
SMO_HUMAN SMO Smoothened homolog 3.938e-11 0.32
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 4.393e-11 0.30
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 4.612e-11 0.38
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 5.752e-11 0.37
ACES_HUMAN ACHE Acetylcholinesterase 5.844e-11 0.35
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 6.094e-11 0.34
TPA_HUMAN PLAT Tissue-type plasminogen activator 7.173e-11 0.33
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 7.953e-11 0.37
Q25856_PLAFA PFG6PD Glucose-6-phosphate dehydrogenase 8.12e-11 0.30
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 8.25e-11 0.31
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 8.581e-11 0.29
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 9.188e-11 0.35
OX2R_HUMAN HCRTR2 Orexin receptor type 2 9.463e-11 0.39
SEPR_MOUSE Fap Prolyl endopeptidase FAP 1.152e-10 0.33
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 1.443e-10 0.33
HRH2_HUMAN HRH2 Histamine H2 receptor 1.491e-10 0.37
Q8JXU8_9HEPC NS5B RNA-directed RNA polymerase 1.545e-10 0.35
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.547e-10 0.31
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 1.58e-10 0.36
HRH1_HUMAN HRH1 Histamine H1 receptor 1.627e-10 0.39
EST1_RABIT Liver carboxylesterase 1 1.654e-10 0.35
STRP_STRP1 ska Streptokinase A 1.688e-10 0.37
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.787e-10 0.46
Q25615_ONCVO Chitinase 1.822e-10 0.29
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 1.861e-10 0.36
GALR2_HUMAN GALR2 Galanin receptor type 2 1.981e-10 0.30
CATK_HUMAN CTSK Cathepsin K 2.013e-10 0.36
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 2.059e-10 0.40
PARP2_HUMAN PARP2 Poly [ADP-ribose] polymerase 2 2.087e-10 0.32
RXFP1_HUMAN RXFP1 Relaxin receptor 1 2.286e-10 0.38
GLR_HUMAN GCGR Glucagon receptor 2.287e-10 0.34
CATK_RABIT CTSK Cathepsin K 2.424e-10 0.37
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 2.548e-10 0.37
ACHA9_RAT Chrna9 Neuronal acetylcholine receptor subunit alpha-9 2.98e-10 0.32
PYGL_RAT Pygl Glycogen phosphorylase, liver form 3.238e-10 0.30
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 3.768e-10 0.39
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 3.773e-10 0.32
DPP2_HUMAN DPP7 Dipeptidyl peptidase 2 4.773e-10 0.35
O96526_LEIMA CRK3 Cdc2-related kinase 5.076e-10 0.29
FFAR1_MOUSE Ffar1 Free fatty acid receptor 1 5.185e-10 0.32
Q9JN24_ECOLX def Peptide deformylase 6.319e-10 0.34
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 6.408e-10 0.34
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 7.049e-10 0.32
PANC_MYCTU panC Pantothenate synthetase 7.631e-10 0.29
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 9.286e-10 0.37
ACRO_HUMAN ACR Acrosin 9.624e-10 0.30
CASP1_HUMAN CASP1 Caspase-1 1.03e-09 0.33
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 1.201e-09 0.48
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 1.291e-09 0.41
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 1.391e-09 0.36
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.541e-09 0.37
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 1.659e-09 0.33
MK07_HUMAN MAPK7 Mitogen-activated protein kinase 7 1.758e-09 0.30
CNR2_HUMAN CNR2 Cannabinoid receptor 2 1.808e-09 0.37
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.13e-09 0.35
GLP1R_RAT Glp1r Glucagon-like peptide 1 receptor 2.406e-09 0.29
ANPRA_HUMAN NPR1 Atrial natriuretic peptide receptor 1 2.796e-09 0.31
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 2.891e-09 0.31
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 3.165e-09 0.32
TPH1_HUMAN TPH1 Tryptophan 5-hydroxylase 1 3.519e-09 0.31
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 3.609e-09 0.32
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 3.688e-09 0.46
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 3.787e-09 0.32
WDR5_HUMAN WDR5 WD repeat-containing protein 5 5.043e-09 0.38
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 5.073e-09 0.39
OPRD_HUMAN OPRD1 Delta-type opioid receptor 5.074e-09 0.40
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 5.561e-09 0.36
KLF5_HUMAN KLF5 Krueppel-like factor 5 6.213e-09 0.33
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 7.125e-09 0.30
RYR2_HUMAN RYR2 Ryanodine receptor 2 8.329e-09 0.30
NPSR1_HUMAN NPSR1 Neuropeptide S receptor 8.56e-09 0.32
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 8.607e-09 0.41
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 9.147e-09 0.38
LMBL1_HUMAN L3MBTL1 Lethal(3)malignant brain tumor-like protein 1 1.173e-08 0.31
TIMP3_RAT Timp3 Metalloproteinase inhibitor 3 1.183e-08 0.30
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.185e-08 0.34
MAP2_HUMAN METAP2 Methionine aminopeptidase 2 1.197e-08 0.41
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 1.263e-08 0.34
V1BR_RAT Avpr1b Vasopressin V1b receptor 1.369e-08 0.28
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.48e-08 0.40
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 1.512e-08 0.28
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 1.559e-08 0.40
LIPL_RAT Lpl Lipoprotein lipase 1.56e-08 0.32
DRD3_CHLAE DRD3 D(3) dopamine receptor 1.576e-08 0.30
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 1.716e-08 0.46
AURKB_HUMAN AURKB Aurora kinase B 1.785e-08 0.36
CTNB1_HUMAN CTNNB1 Catenin beta-1 1.856e-08 0.32
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 1.957e-08 0.33
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 2.375e-08 0.33
SENP6_HUMAN SENP6 Sentrin-specific protease 6 2.39e-08 0.34
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 2.414e-08 0.34
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 2.42e-08 0.34
MITF_HUMAN MITF Microphthalmia-associated transcription factor 2.446e-08 0.38
TIF1A_HUMAN TRIM24 Transcription intermediary factor 1-alpha 2.55e-08 0.31
GP183_HUMAN GPR183 G-protein coupled receptor 183 2.623e-08 0.31
LMBL3_HUMAN L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 2.745e-08 0.31
CNR1_HUMAN CNR1 Cannabinoid receptor 1 3.469e-08 0.36
MMP9_RAT Mmp9 Matrix metalloproteinase-9 3.664e-08 0.30
PDE4C_HUMAN PDE4C cAMP-specific 3',5'-cyclic phosphodiesterase 4C 3.763e-08 0.34
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 4.315e-08 0.40
DRD2_MOUSE Drd2 D(2) dopamine receptor 4.536e-08 0.37
MC5R_HUMAN MC5R Melanocortin receptor 5 4.729e-08 0.35
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 4.951e-08 0.28
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 6.089e-08 0.34
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 6.582e-08 0.36
KCNJ3_RAT Kcnj3 G protein-activated inward rectifier potassium channel 1 6.64e-08 0.32
KCNJ5_RAT Kcnj5 G protein-activated inward rectifier potassium channel 4 6.64e-08 0.32
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 6.729e-08 0.29
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 7.455e-08 0.33
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 8.375e-08 0.39
MYO3A_HUMAN MYO3A Myosin-IIIa 8.63e-08 0.29
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 8.712e-08 0.34
DPP4_HUMAN DPP4 Dipeptidyl peptidase 4 9.571e-08 0.41
PDIA1_HUMAN P4HB Protein disulfide-isomerase 9.63e-08 0.41
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.055e-07 0.29
LYAM3_HUMAN SELP P-selectin 1.26e-07 0.33
REV1_HUMAN REV1 DNA repair protein REV1 1.291e-07 0.28
PA_I34A1 PA Polymerase acidic protein 1.332e-07 0.34
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 1.336e-07 0.38
VACHT_RAT Slc18a3 Vesicular acetylcholine transporter 1.363e-07 0.33
SENP8_HUMAN SENP8 Sentrin-specific protease 8 1.545e-07 0.33
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 1.552e-07 0.32
PD1L1_HUMAN CD274 Programmed cell death 1 ligand 1 1.631e-07 0.29
HRH2_CAVPO HRH2 Histamine H2 receptor 1.647e-07 0.35
GLUC_HUMAN GCG Glucagon 1.66e-07 0.33
IL6_HUMAN IL6 Interleukin-6 1.679e-07 0.29
O97467_PLAFA ht1 Hexose transporter 1 1.684e-07 0.36
CHLE_HORSE BCHE Cholinesterase 1.713e-07 0.37
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 1.762e-07 0.36
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.879e-07 0.38
O61059_LEIME LmGT2 Glucose transporter 1.9e-07 0.36
ANDR_MOUSE Ar Androgen receptor 1.934e-07 0.31
MYO3B_HUMAN MYO3B Myosin-IIIb 1.995e-07 0.29
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 2.488e-07 0.36
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 2.68e-07 0.28
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.74e-07 0.36
MMP12_MOUSE Mmp12 Macrophage metalloelastase 2.807e-07 0.32
S12A5_RAT Slc12a5 Solute carrier family 12 member 5 3.199e-07 0.30
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 3.23e-07 0.36
GLMU_ECOLI glmU Bifunctional protein GlmU 3.61e-07 0.29
HDAC5_HUMAN HDAC5 Histone deacetylase 5 3.617e-07 0.33
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 3.68e-07 0.36
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 3.687e-07 0.37
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 3.717e-07 0.30
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 3.78e-07 0.36
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 4.177e-07 0.29
AA1R_HUMAN ADORA1 Adenosine receptor A1 4.312e-07 0.36
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 4.508e-07 0.37
HSF1_MOUSE Hsf1 Heat shock factor protein 1 4.552e-07 0.37
LUCI_AQULA Luciferin 4-monooxygenase 5.114e-07 0.35
PDE1B_HUMAN PDE1B Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B 5.215e-07 0.33
HRH1_CAVPO HRH1 Histamine H1 receptor 5.326e-07 0.35
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 5.351e-07 0.33
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 5.491e-07 0.31
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 5.978e-07 0.33
CYNT_HELPY cynT Carbonic anhydrase 6.106e-07 0.31
SYK_HUMAN KARS1 Lysine--tRNA ligase 6.55e-07 0.29
ALK_HUMAN ALK ALK tyrosine kinase receptor 7.509e-07 0.33
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 7.93e-07 0.34
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 7.958e-07 0.32
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 8.058e-07 0.29
NIM1_HUMAN NIM1K Serine/threonine-protein kinase NIM1 8.058e-07 0.29
RORG_MOUSE Rorc Nuclear receptor ROR-gamma 8.109e-07 0.31
ITB1_HUMAN ITGB1 Integrin beta-1 8.152e-07 0.36
RCE1_YEAST RCE1 CAAX prenyl protease 2 8.28e-07 0.33
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 8.926e-07 0.36
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 9.359e-07 0.34
CCNA2_HUMAN CCNA2 Cyclin-A2 1.145e-06 0.35
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 1.179e-06 0.33
BRPF3_HUMAN BRPF3 Bromodomain and PHD finger-containing protein 3 1.212e-06 0.37
WNT3_HUMAN WNT3 Proto-oncogene Wnt-3 1.234e-06 0.37
Q8MWR1_SPOFR USP Ultraspiracle protein 1.281e-06 0.34
Q8MWR2_SPOFR EcR Ecdysteroid receptor 1.281e-06 0.34
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 1.336e-06 0.29
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 1.336e-06 0.29
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 1.336e-06 0.29
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 1.336e-06 0.29
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 1.336e-06 0.29
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 1.336e-06 0.29
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 1.336e-06 0.29
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 1.336e-06 0.29
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 1.336e-06 0.29
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 1.336e-06 0.29
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 1.336e-06 0.29
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 1.336e-06 0.29
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 1.336e-06 0.29
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 1.336e-06 0.29
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 1.336e-06 0.29
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 1.336e-06 0.29
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 1.336e-06 0.29
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 1.336e-06 0.29
PRGR_RABIT PGR Progesterone receptor 1.419e-06 0.31
HSF1_HUMAN HSF1 Heat shock factor protein 1 1.431e-06 0.29
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 1.469e-06 0.31
H9B8T9_CAPHI CTSB Cathepsin B 1.71e-06 0.38
SL9A3_HUMAN SLC9A3 Sodium/hydrogen exchanger 3 1.717e-06 0.30
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 1.832e-06 0.30
HDAC1_MOUSE Hdac1 Histone deacetylase 1 1.842e-06 0.34
TLR1_MOUSE Tlr1 Toll-like receptor 1 1.905e-06 0.33
TLR2_MOUSE Tlr2 Toll-like receptor 2 1.905e-06 0.33
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 1.945e-06 0.33
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 2.021e-06 0.29
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 2.113e-06 0.34
DRD1_PIG DRD1 D(1A) dopamine receptor 2.143e-06 0.31
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.185e-06 0.29
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 2.238e-06 0.34
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 2.279e-06 0.34
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 2.293e-06 0.30
NR5A2_HUMAN NR5A2 Nuclear receptor subfamily 5 group A member 2 2.618e-06 0.28
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 2.631e-06 0.30
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 2.787e-06 0.37
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 2.976e-06 0.30
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 3.009e-06 0.31
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 3.108e-06 0.35
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 3.129e-06 0.37
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 3.171e-06 0.35
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 3.616e-06 0.34
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 3.659e-06 0.42
ACES_ELEEL ache Acetylcholinesterase 3.775e-06 0.35
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 3.892e-06 0.32
KLK7_HUMAN KLK7 Kallikrein-7 4.019e-06 0.33
ECR_BOMMO EcR Ecdysone receptor 4.043e-06 0.34
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 4.131e-06 0.40
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 4.23e-06 0.33
PRIO_HUMAN PRNP Major prion protein 4.647e-06 0.32
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 4.744e-06 0.30
PA21B_HUMAN PLA2G1B Phospholipase A2 4.75e-06 0.34
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 4.967e-06 0.35
LYOX_HUMAN LOX Protein-lysine 6-oxidase 5.186e-06 0.29
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 5.252e-06 0.32
POL_HV1A2 gag-pol Gag-Pol polyprotein 5.31e-06 0.28
TERT_HUMAN TERT Telomerase reverse transcriptase 5.64e-06 0.34
C3SLB7_ECOLX glmU Bifunctional protein GlmU 5.752e-06 0.28
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 5.926e-06 0.30
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 6.09e-06 0.33
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 6.209e-06 0.32
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 6.655e-06 0.33
PLMN_HUMAN PLG Plasminogen 6.853e-06 0.33
GALR1_HUMAN GALR1 Galanin receptor type 1 7.367e-06 0.30
LCK_HUMAN LCK Tyrosine-protein kinase Lck 7.442e-06 0.36
AA1R_BOVIN ADORA1 Adenosine receptor A1 7.717e-06 0.35
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 7.732e-06 0.37
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 7.871e-06 0.32
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 8.17e-06 0.34
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 8.628e-06 0.39
INCE_HUMAN INCENP Inner centromere protein 8.904e-06 0.30
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 9.18e-06 0.34
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 9.936e-06 0.38
TYRO3_HUMAN TYRO3 Tyrosine-protein kinase receptor TYRO3 9.992e-06 0.33

Lomustine

HYEP_MOUSE Ephx1 Epoxide hydrolase 1 1.802e-129 0.42
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.976e-91 0.42
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 7.554e-22 0.40
EPHB_MYCTO Epoxide hydrolase B 5.429e-20 0.32
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 4.032e-13 0.28
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 7.533e-10 0.34
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.75e-09 0.42
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 6.141e-09 0.34
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 8.775e-08 0.30
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 1.614e-07 0.35
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 6.302e-07 0.53
PRIO_MESAU PRNP Major prion protein 3.213e-06 0.28
NCOA1_HUMAN NCOA1 Nuclear receptor coactivator 1 4.646e-06 0.29
CBPA1_BOVIN CPA1 Carboxypeptidase A1 7.305e-06 0.30

Aminophylline

AA2AR_CAVPO ADORA2A Adenosine receptor A2a 2.939e-114 0.65
CHIB1_ASPFM chiB1 Endochitinase B1 1.245e-58 0.35
AA1R_CAVPO ADORA1 Adenosine receptor A1 1.444e-47 0.84
AA1R_BOVIN ADORA1 Adenosine receptor A1 4.129e-36 0.84
AA1R_RAT Adora1 Adenosine receptor A1 4.175e-34 0.84
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 3.921e-28 0.31
AA2BR_RAT Adora2b Adenosine receptor A2b 5.473e-27 0.57
AA2AR_RAT Adora2a Adenosine receptor A2a 2.779e-21 0.84
GUAD_HUMAN GDA Guanine deaminase 1.453e-20 0.29
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 5.283e-20 0.84
PERT_HUMAN TPO Thyroid peroxidase 9.771e-18 0.28
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 1.11e-16 0.37
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 1.493e-11 0.84
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 2.06e-11 0.37
BGAL_ECOLX lacZ Beta-galactosidase 1.59e-10 0.32
CNOT7_HUMAN CNOT7 CCR4-NOT transcription complex subunit 7 4.675e-08 0.28
CHIA_MOUSE Chia Acidic mammalian chitinase 2.417e-06 0.33
PNPH_RAT Pnp Purine nucleoside phosphorylase 3.025e-06 0.30
NCOA3_HUMAN NCOA3 Nuclear receptor coactivator 3 3.561e-06 0.38

Isocarboxazid

SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 3.853e-102 0.40
SGPL1_HUMAN SGPL1 Sphingosine-1-phosphate lyase 1 5.176e-85 0.42
PDS_SYNE7 pds 15-cis-phytoene desaturase 1.929e-61 0.34
PFKA_TRYCC pfk ATP-dependent 6-phosphofructokinase 6.392e-59 0.34
PFKA_TRYBB pfk ATP-dependent 6-phosphofructokinase 1.047e-54 0.34
GBRA5_HUMAN GABRA5 Gamma-aminobutyric acid receptor subunit alpha-5 3.973e-45 0.33
PHHY_PSEFL pobA p-hydroxybenzoate hydroxylase 6.694e-38 0.30
A0A1D8D5K2_HE71 Genome polyprotein 2.333e-36 0.29
CAC1I_HUMAN CACNA1I Voltage-dependent T-type calcium channel subunit alpha-1I 4.322e-34 0.32
POLG_CXB3N Genome polyprotein 1.673e-30 0.39
Q31945_CHEAL Chloroplast thylakoid membrane protein (psbA) 1.349e-29 0.29
ACOD1_MOUSE Scd1 Acyl-CoA desaturase 1 1.006e-27 0.40
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 6.636e-26 0.35
KLKB1_HUMAN KLKB1 Plasma kallikrein 4.433e-23 0.38
CAC1H_HUMAN CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H 8.701e-21 0.31
ACRO_HUMAN ACR Acrosin 3.321e-19 0.32
MTSI_SPISQ sssIM CPG DNA methylase 3.79e-19 0.34
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.291e-18 0.35
GLUP_BACSU gluP Rhomboid protease GluP 9.771e-18 0.28
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 3.929e-17 0.33
PPAP_HUMAN ACP3 Prostatic acid phosphatase 5.551e-16 0.31
VE1_HPV11 E1 Replication protein E1 5.551e-16 0.29
Q6UCJ9_TOXGO ENR Enoyl-acyl carrier reductase 6.661e-16 0.40
MMP13_MOUSE Mmp13 Collagenase 3 1.443e-15 0.35
ASAH1_HUMAN ASAH1 Acid ceramidase 2.776e-15 0.30
COX2_HUMAN MT-CO2 Cytochrome c oxidase subunit 2 4.441e-15 0.29
PANC_MYCTU panC Pantothenate synthetase 5.107e-15 0.36
SCAF_HHV11 UL26 Capsid scaffolding protein 7.772e-15 0.30
ACOD_HUMAN SCD Acyl-CoA desaturase 1.255e-14 0.37
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.521e-14 0.36
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 6.717e-14 0.32
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 1.218e-13 0.31
A3EZJ3_9HEPC NS3 Genome polyprotein 1.32e-13 0.35
EST1_HUMAN CES1 Liver carboxylesterase 1 3.222e-13 0.35
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 4.495e-13 0.31
ADH1G_HUMAN ADH1C Alcohol dehydrogenase 1C 1.191e-12 0.31
NR1H4_HUMAN NR1H4 Bile acid receptor 2.157e-12 0.31
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 2.299e-12 0.35
ARBK1_HUMAN GRK2 Beta-adrenergic receptor kinase 1 3.432e-12 0.33
HDAC8_HUMAN HDAC8 Histone deacetylase 8 4.231e-12 0.37
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 4.251e-12 0.30
PETD_SPIOL petD Cytochrome b6-f complex subunit 4 4.361e-12 0.30
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 4.728e-12 0.34
RS27_HUMAN RPS27 40S ribosomal protein S27 5.866e-12 0.32
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 6.181e-12 0.35
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 7.542e-12 0.37
Q05BA5_MOUSE Ncoa3 Nuclear receptor coactivator 1.437e-11 0.28
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 4.703e-11 0.30
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 5.829e-11 0.46
CBS_HUMAN CBS Cystathionine beta-synthase 8.878e-11 0.29
AOFB_RAT Maob Amine oxidase [flavin-containing] B 1.067e-10 0.35
Q9FD53_STREE mvaD Diphosphomevalonate decarboxylase 1.336e-10 0.28
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.961e-10 0.33
HDAC1_HUMAN HDAC1 Histone deacetylase 1 2.266e-10 0.42
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 2.395e-10 0.36
GBRA1_RAT Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 3.299e-10 0.33
PRIO_HUMAN PRNP Major prion protein 4.526e-10 0.35
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 5.044e-10 0.33
Q7T1G6_DANRE trpn1 Ion channel NompC 5.047e-10 0.31
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 6.171e-10 0.29
ADH1B_HUMAN ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH1B 7.2e-10 0.31
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.345e-09 0.39
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 1.573e-09 0.31
GBRG2_RAT Gabrg2 Gamma-aminobutyric acid receptor subunit gamma-2 2.733e-09 0.33
P2RX1_MOUSE P2rx1 P2X purinoceptor 1 2.988e-09 0.29
Q9BRH5_HUMAN DGAT1 DGAT1 protein 3.225e-09 0.40
HDAC6_HUMAN HDAC6 Histone deacetylase 6 4.201e-09 0.42
HCAR2_RAT Hcar2 Hydroxycarboxylic acid receptor 2 6.432e-09 0.30
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 7.773e-09 0.29
P2RX4_RAT P2rx4 P2X purinoceptor 4 1.111e-08 0.29
A5H660_SCHMA HDAC8 Histone deacetylase 8 1.157e-08 0.34
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 1.189e-08 0.29
ARBK2_HUMAN GRK3 Beta-adrenergic receptor kinase 2 1.729e-08 0.29
AMP1_PLAFQ M1 family aminopeptidase 1.839e-08 0.31
AMPN_PIG ANPEP Aminopeptidase N 2.173e-08 0.31
CHLE_HUMAN BCHE Cholinesterase 2.397e-08 0.33
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 2.399e-08 0.31
NEP_RAT Mme Neprilysin 2.426e-08 0.30
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 2.613e-08 0.29
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 3.573e-08 0.43
LEG7_HUMAN LGALS7; LGALS7B Galectin-7 5.037e-08 0.30
EGLN1_HUMAN EGLN1 Egl nine homolog 1 5.759e-08 0.32
TSPO_RAT Tspo Translocator protein 7.046e-08 0.38
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 7.164e-08 0.36
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 7.79e-08 0.36
GATA4_MOUSE Gata4 Transcription factor GATA-4 7.801e-08 0.32
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 7.801e-08 0.32
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 8.485e-08 0.31
TA2R8_HUMAN TAS2R8 Taste receptor type 2 member 8 1.069e-07 0.33
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 1.239e-07 0.41
EGFR_MOUSE Egfr Epidermal growth factor receptor 1.41e-07 0.31
AA1R_BOVIN ADORA1 Adenosine receptor A1 1.47e-07 0.35
HDAC2_HUMAN HDAC2 Histone deacetylase 2 1.62e-07 0.35
KLK1_HUMAN KLK1 Kallikrein-1 1.728e-07 0.31
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 1.841e-07 0.31
FUCO_HUMAN FUCA1 Tissue alpha-L-fucosidase 2.222e-07 0.32
POLG_WNV Genome polyprotein 2.648e-07 0.31
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 2.744e-07 0.29
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 4.385e-07 0.33
DCTP1_HUMAN DCTPP1 dCTP pyrophosphatase 1 4.76e-07 0.30
STRP_STRP1 ska Streptokinase A 4.817e-07 0.35
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 4.941e-07 0.31
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 4.989e-07 0.41
NR4A2_HUMAN NR4A2 Nuclear receptor subfamily 4 group A member 2 5.464e-07 0.28
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 6.624e-07 0.37
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 7.093e-07 0.54
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 7.155e-07 0.31
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 8.105e-07 0.29
LEG9_HUMAN LGALS9 Galectin-9 9.298e-07 0.30
KS6B2_HUMAN RPS6KB2 Ribosomal protein S6 kinase beta-2 1.198e-06 0.28
DXR_MYCTU dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.41e-06 0.30
TOP3_BACSU topB DNA topoisomerase 3 1.454e-06 0.31
AA1R_HUMAN ADORA1 Adenosine receptor A1 1.53e-06 0.35
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 1.555e-06 0.33
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 2.438e-06 0.31
EGLN3_HUMAN EGLN3 Egl nine homolog 3 2.558e-06 0.30
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 2.577e-06 0.36
TLR7_HUMAN TLR7 Toll-like receptor 7 3.512e-06 0.33
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 4.084e-06 0.29
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 4.142e-06 0.29
CPNS1_PIG CAPNS1 Calpain small subunit 1 4.478e-06 0.32
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 4.596e-06 0.29
BLA2_BACCE blm Metallo-beta-lactamase type 2 4.749e-06 0.30
AGP1_YEAST AGP1 General amino acid permease AGP1 5.99e-06 0.29
OXDA_PIG DAO D-amino-acid oxidase 6.141e-06 0.30
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 6.318e-06 0.33
PTN7_HUMAN PTPN7 Tyrosine-protein phosphatase non-receptor type 7 6.803e-06 0.37
LYOX_HUMAN LOX Protein-lysine 6-oxidase 7.112e-06 0.29
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 7.839e-06 0.32
AMPN_HUMAN ANPEP Aminopeptidase N 7.963e-06 0.33

Metipranolol

B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 4.27e-99 0.49
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 1.188e-85 0.53
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 3.445e-78 0.48
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 6.767e-74 0.53
ADRB2_MOUSE Adrb2 Beta-2 adrenergic receptor 1.634e-72 0.34
DNMT1_MOUSE Dnmt1 DNA (cytosine-5)-methyltransferase 1 3.233e-35 0.34
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 2.136e-23 0.48
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 7.357e-22 0.48
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 4.441e-15 0.36
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 5.196e-14 0.40
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 5.125e-13 0.28
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 1.435e-11 0.49
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 5.447e-10 0.48
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 8.133e-10 0.36
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 2.725e-07 0.28
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.285e-06 0.30
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.395e-06 0.48
FDFT_RAT Fdft1 Squalene synthase 1.997e-06 0.47
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 3.815e-06 0.44

Desonide

ATTY_RAT Tat Tyrosine aminotransferase 2.178e-93 0.35
GCR_RAT Nr3c1 Glucocorticoid receptor 1.914e-60 0.73
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 4.445e-60 0.62
Q690N0_BOVIN PGR Progesterone receptor 4.697e-58 0.73
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 3.407e-39 0.36
GCR_HUMAN NR3C1 Glucocorticoid receptor 6.403e-38 0.73
GCR_MOUSE Nr3c1 Glucocorticoid receptor 5.642e-36 0.62
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 3.978e-19 0.62
GLNA_HUMAN GLUL Glutamine synthetase 3.978e-19 0.62
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.348e-18 0.42
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.776e-15 0.36
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 2.22e-15 0.36
IL6_HUMAN IL6 Interleukin-6 3.553e-15 0.62
NOS2_RAT Nos2 Nitric oxide synthase, inducible 2.289e-13 0.29
CP19A_HUMAN CYP19A1 Aromatase 2.856e-09 0.39
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.282e-07 0.36

Nadolol

B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 4.459e-93 0.46
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 2.889e-89 0.46
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 1.711e-69 0.42
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 3.955e-60 0.52
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 1.238e-45 0.52
CASR_BOVIN CASR Extracellular calcium-sensing receptor 5.965e-45 0.36
CASR_HUMAN CASR Extracellular calcium-sensing receptor 8.377e-42 0.41
Q5YLN7_CANLF SCN5A Voltage-gated sodium channel Nav1.5 cardiac isoform 1.947e-38 0.30
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 2.428e-31 0.33
MEP50_HUMAN WDR77 Methylosome protein 50 4.715e-31 0.33
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 3.987e-23 0.38
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 6.455e-23 0.57
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 6.575e-20 0.57
SCN9A_MOUSE Scn9a Sodium channel protein type 9 subunit alpha 6.693e-20 0.32
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 8.984e-20 0.31
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 7.461e-18 0.39
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 1.443e-15 0.57
SCN1A_HUMAN SCN1A Sodium channel protein type 1 subunit alpha 1.554e-15 0.31
ADRB2_MOUSE Adrb2 Beta-2 adrenergic receptor 2.443e-12 0.30
CASR_RAT Casr Extracellular calcium-sensing receptor 6.219e-12 0.39
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 5.24e-11 0.30
PI2R_HUMAN PTGIR Prostacyclin receptor 2.397e-08 0.31
MTR1B_CHICK Melatonin receptor type 1B 1.84e-07 0.31
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 7.632e-07 0.33
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 3.273e-06 0.45
NR1H4_MOUSE Nr1h4 Bile acid receptor 5.463e-06 0.28
Q72874_9HIV1 pol Pol polyprotein 6.778e-06 0.33
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 6.797e-06 0.39

Flumazenil

GBRA6_HUMAN GABRA6 Gamma-aminobutyric acid receptor subunit alpha-6 1.516e-89 0.80
GBRA4_HUMAN GABRA4 Gamma-aminobutyric acid receptor subunit alpha-4 1.409e-64 0.74
GBRG2_HUMAN GABRG2 Gamma-aminobutyric acid receptor subunit gamma-2 3.605e-61 0.80
GBRB3_HUMAN GABRB3 Gamma-aminobutyric acid receptor subunit beta-3 1.017e-53 0.74
GBRA2_HUMAN GABRA2 Gamma-aminobutyric acid receptor subunit alpha-2 3.943e-47 0.80
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 3.718e-46 0.80
GBRA3_HUMAN GABRA3 Gamma-aminobutyric acid receptor subunit alpha-3 1.286e-41 0.80
RICI_RICCO Ricin 6.27e-39 0.32
GBRA1_HUMAN GABRA1 Gamma-aminobutyric acid receptor subunit alpha-1 3.045e-36 0.80
GBRA5_HUMAN GABRA5 Gamma-aminobutyric acid receptor subunit alpha-5 8.875e-35 0.74
CDK9_HUMAN CDK9 Cyclin-dependent kinase 9 2.438e-33 0.37
Q03732_HBV HBcAg Capsid protein 1.823e-20 0.31
TRPC7_HUMAN TRPC7 Short transient receptor potential channel 7 2.442e-15 0.29
AMPD3_HUMAN AMPD3 AMP deaminase 3 1.024e-12 0.29
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 4.229e-11 0.29
TRPC6_MOUSE Trpc6 Short transient receptor potential channel 6 7.173e-11 0.29
XPO1_HUMAN XPO1 Exportin-1 5.669e-09 0.33
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 1.276e-07 0.30
ELNE_HUMAN ELANE Neutrophil elastase 3.29e-07 0.38
A3KMY8_BOVIN GUSB Beta-glucuronidase 5.53e-07 0.31
FOS_HUMAN FOS Proto-oncogene c-Fos 1.119e-06 0.32
GBRA5_RAT Gabra5 Gamma-aminobutyric acid receptor subunit alpha-5 2.089e-06 0.55
NORA_STAAU norA Quinolone resistance protein NorA 2.316e-06 0.30
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 4.736e-06 0.31
PERF_HUMAN PRF1 Perforin-1 5.026e-06 0.31
MK11_HUMAN MAPK11 Mitogen-activated protein kinase 11 6.906e-06 0.31

Epoprostenol

PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 1.046e-88 0.56
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 1.826e-87 0.56
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 9.099e-84 0.56
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 6.67e-83 0.56
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 7.712e-79 0.56
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 3.933e-58 0.56
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 1.493e-56 0.56
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 4.306e-51 0.56
PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 4.311e-48 0.56
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 9.423e-40 0.29
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 4.791e-34 0.56
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 4.935e-31 0.56
PE2R4_RABIT PTGER4 Prostaglandin E2 receptor EP4 subtype 5.245e-27 0.33
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 5.831e-26 0.56
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.608e-25 0.56
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 4.308e-24 0.56
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.274e-18 0.56
PI2R_HUMAN PTGIR Prostacyclin receptor 1.996e-18 0.56
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 2.832e-18 0.56
GLCM_MOUSE Gba Lysosomal acid glucosylceramidase 1.07e-17 0.28
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 1.201e-17 0.56
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 1.11e-16 0.37
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 7.772e-16 0.56
TA2R_RAT Tbxa2r Thromboxane A2 receptor 1.086e-11 0.52
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 2.961e-08 0.56
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 1.074e-07 0.36
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 9.773e-07 0.31
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.827e-06 0.28
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 7.953e-06 0.28

Olsalazine

HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 2.775e-83 0.55
MGRA_STAAU mgrA HTH-type transcriptional regulator MgrA 1.091e-66 0.53
POL_RSVP gag-pol Gag-Pol polyprotein 5.637e-63 0.40
Q2PCB5_DICLA ca Carbonic anhydrase 1.669e-48 0.40
PTN9_HUMAN PTPN9 Tyrosine-protein phosphatase non-receptor type 9 4.364e-44 0.31
CO9_HUMAN C9 Complement component C9 1.935e-43 0.38
PHHY_PSEFL pobA p-hydroxybenzoate hydroxylase 5.512e-41 0.33
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 1.706e-40 0.36
TCMO_HELTU CYP73A1 Trans-cinnamate 4-monooxygenase 1.381e-38 0.31
RAGE_RAT Ager Advanced glycosylation end product-specific receptor 3.875e-36 0.29
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 4.005e-36 0.34
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 1.464e-33 0.61
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 3.707e-32 0.36
PTN22_HUMAN PTPN22 Tyrosine-protein phosphatase non-receptor type 22 3.504e-28 0.35
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 2.504e-26 0.34
HMGB1_HUMAN HMGB1 High mobility group protein B1 1.246e-25 0.32
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 2.102e-25 0.36
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 3.161e-25 0.34
MYOC_HUMAN MYOC Myocilin 2.158e-24 0.30
POLI_HUMAN POLI DNA polymerase iota 9.074e-24 0.38
PTPRO_HUMAN PTPRO Receptor-type tyrosine-protein phosphatase O 5.448e-22 0.31
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 7.953e-20 0.38
POLH_HUMAN POLH DNA polymerase eta 7.953e-20 0.38
AOX_TRYBB AOX Alternative oxidase, mitochondrial 1.846e-19 0.33
O49150_SOLTU Lipoxygenase 1.991e-19 0.41
AAKB2_HUMAN PRKAB2 5'-AMP-activated protein kinase subunit beta-2 1.265e-18 0.30
CAH3_HUMAN CA3 Carbonic anhydrase 3 4.11e-18 0.38
CC14A_HUMAN CDC14A Dual specificity protein phosphatase CDC14A 9.771e-18 0.28
FUT7_HUMAN FUT7 Alpha-(1,3)-fucosyltransferase 7 3.634e-17 0.38
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.254e-14 0.36
GBB1_HUMAN GNB1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 4.718e-14 0.33
GBG2_HUMAN GNG2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 4.718e-14 0.33
Q9AQH7_STAAU dnaC Replicative DNA helicase 6.761e-14 0.34
P89582_9HIV2 pol Integrase 2.701e-13 0.29
TYRO_MOUSE Tyr Tyrosinase 2.111e-12 0.30
CAH13_MOUSE Ca13 Carbonic anhydrase 13 3.698e-12 0.38
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 3.922e-12 0.31
PTPRG_HUMAN PTPRG Receptor-type tyrosine-protein phosphatase gamma 3.922e-12 0.31
POLG_DEN2P Genome polyprotein 5.877e-12 0.53
DUS22_HUMAN DUSP22 Dual specificity protein phosphatase 22 1.038e-11 0.31
Q7ZJM1_9HIV1 pol Integrase 1.289e-11 0.40
CAH15_MOUSE Ca15 Carbonic anhydrase 15 1.74e-11 0.32
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 1.929e-11 0.37
DYN2_HUMAN DNM2 Dynamin-2 3.87e-11 0.30
CAH14_HUMAN CA14 Carbonic anhydrase 14 9.499e-11 0.40
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.347e-10 0.38
CAH6_HUMAN CA6 Carbonic anhydrase 6 3.226e-10 0.40
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 4.452e-10 0.31
IBP5_HUMAN IGFBP5 Insulin-like growth factor-binding protein 5 5.888e-10 0.31
CAH7_HUMAN CA7 Carbonic anhydrase 7 3.057e-09 0.40
P2RX4_RAT P2rx4 P2X purinoceptor 4 3.895e-09 0.31
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 4.814e-09 0.31
INSR_MOUSE Insr Insulin receptor 4.818e-09 0.34
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 6.429e-09 0.38
GLRA3_HUMAN GLRA3 Glycine receptor subunit alpha-3 1.322e-08 0.29
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 5.917e-08 0.34
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 1.266e-07 0.28
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 1.354e-07 0.34
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 2.869e-07 0.28
TTHY_HUMAN TTR Transthyretin 3.227e-07 0.42
PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 6.327e-07 0.34
NOX4_HUMAN NOX4 NADPH oxidase 4 7.265e-07 0.42
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 7.672e-07 0.47
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 9.316e-07 0.36
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.007e-06 0.42
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 1.316e-06 0.30
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 1.719e-06 0.34
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 2.044e-06 0.34
KCNQ2_RAT Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 2.174e-06 0.39
DUS3_HUMAN DUSP3 Dual specificity protein phosphatase 3 3.238e-06 0.34
GRM6_RAT Grm6 Metabotropic glutamate receptor 6 4.4e-06 0.30
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 6.962e-06 0.41
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 7.357e-06 0.52

Mivacurium

S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 3.147e-72 0.34
ACHB4_MOUSE Chrnb4 Neuronal acetylcholine receptor subunit beta-4 1.483e-20 0.40
ACHB2_MOUSE Chrnb2 Neuronal acetylcholine receptor subunit beta-2 3.184e-19 0.40
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 2.063e-17 0.29
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 1.11e-16 0.33
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 4.7e-11 0.34
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.414e-09 0.35
KCNN1_HUMAN KCNN1 Small conductance calcium-activated potassium channel protein 1 1.516e-09 0.30
KCNN2_HUMAN KCNN2 Small conductance calcium-activated potassium channel protein 2 5.037e-08 0.30
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 1.037e-07 0.30
KCNN3_RAT Kcnn3 Small conductance calcium-activated potassium channel protein 3 1.514e-07 0.69
MIP_LEGPN mip Outer membrane protein MIP 5.282e-07 0.30
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 6.121e-07 0.35
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 7.084e-07 0.35
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 2.746e-06 0.32
KCNN3_HUMAN KCNN3 Small conductance calcium-activated potassium channel protein 3 9.348e-06 0.30

Bromodiphenhydramine

Q5TIX5_MYCSM atpE ATP synthase subunit c 5.121e-61 0.33
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 8.773e-53 0.54
ATPL_BACP3 atpE ATP synthase subunit c 5.166e-42 0.33
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 3.495e-40 0.51
ATP6_MYCTU atpB ATP synthase subunit a 2.664e-35 0.34
ATPA_MYCTU atpA ATP synthase subunit alpha 2.664e-35 0.34
ATPB_MYCTU atpD ATP synthase subunit beta 2.664e-35 0.34
ATPE_MYCTU atpC ATP synthase epsilon chain 2.664e-35 0.34
ATPFD_MYCTU atpFH ATP synthase subunit b-delta 2.664e-35 0.34
ATPF_MYCTU atpF ATP synthase subunit b 2.664e-35 0.34
ATPG_MYCTU atpG ATP synthase gamma chain 2.664e-35 0.34
ATPL_MYCTU atpE ATP synthase subunit c 2.664e-35 0.34
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 8.827e-32 0.31
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 4.133e-26 0.40
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 6.951e-20 0.81
UR2R_HUMAN UTS2R Urotensin-2 receptor 2.943e-18 0.34
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 1.11e-16 0.39
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.277e-14 0.62
AMYP_RAT Amy2 Pancreatic alpha-amylase 6.672e-14 0.30
ANM1_RAT Prmt1 Protein arginine N-methyltransferase 1 5.743e-12 0.29
Q9WTR4_RAT Slc6a2 Transporter 1.703e-11 0.47
HRH1_CAVPO HRH1 Histamine H1 receptor 3.58e-11 0.81
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 1.623e-10 0.81
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.141e-07 0.36
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 1.227e-07 0.28
AOC3_HUMAN AOC3 Membrane primary amine oxidase 1.499e-07 0.32
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.135e-07 0.81
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 9.838e-07 0.40
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 3.101e-06 0.33

Sparfloxacin

Q47245_ECOLX gyrA DNA gyrase subunit A 1.584e-58 0.43
C3SLN2_ECOLX gyrB DNA gyrase subunit B 1.099e-50 0.43
ACEA_MYCTU icl Isocitrate lyase 2.546e-49 0.37
VATB2_HUMAN ATP6V1B2 V-type proton ATPase subunit B, brain isoform 4.536e-38 0.30
DPO3_BACSU polC DNA polymerase III PolC-type 4.23e-18 0.38
PARC_STAAU parC DNA topoisomerase 4 subunit A 4.885e-15 0.49
DPO1_THEAQ polA DNA polymerase I, thermostable 7.883e-15 0.30
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 5.507e-14 0.30
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 1.121e-13 0.62
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 6.126e-10 0.36
GYRA_MYCTU gyrA DNA gyrase subunit A 3.554e-09 0.49
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.64e-08 0.39
MAPK3_HUMAN MAPKAPK3 MAP kinase-activated protein kinase 3 2.672e-08 0.39
GYRA_STAAU gyrA DNA gyrase subunit A 8.477e-08 0.43
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 7.175e-07 0.36
GYRA_ECOLI gyrA DNA gyrase subunit A 2.488e-06 0.42
PARE_STAAU parE DNA topoisomerase 4 subunit B 7.162e-06 0.39

Gemfibrozil

LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 3.783e-56 0.35
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 1.039e-26 0.45
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 7.66e-25 0.40
GRM3_RAT Grm3 Metabotropic glutamate receptor 3 2.344e-21 0.33
FFAR4_MOUSE Ffar4 Free fatty acid receptor 4 7.758e-18 0.33
ETHR_MYCS2 ethR HTH-type transcriptional regulator EthR 9.056e-18 0.28
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 3.442e-15 0.67
ANDR_MOUSE Ar Androgen receptor 7.994e-15 0.33
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 6.745e-12 0.39
S13A5_HUMAN SLC13A5 Solute carrier family 13 member 5 2.633e-11 0.36
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 7.03e-11 0.33
TAT_HV1H2 tat Protein Tat 9.181e-10 0.28
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 6.808e-09 0.31
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 1.281e-08 0.36
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 2.298e-08 0.36
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 4.633e-08 0.30
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 2.173e-07 0.31
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 3.032e-07 0.31
AMPD2_HUMAN AMPD2 AMP deaminase 2 1.876e-06 0.30
RARB_HUMAN RARB Retinoic acid receptor beta 2.552e-06 0.36
THAS_HUMAN TBXAS1 Thromboxane-A synthase 4.98e-06 0.35
DPOL_VACCW POL DNA polymerase 7.112e-06 0.29

Iophendylate

POLI_MOUSE Poli DNA polymerase iota 2.914e-47 0.31
DPOLM_HUMAN POLM DNA-directed DNA/RNA polymerase mu 3.543e-39 0.31
PA2A1_NAJMO Acidic phospholipase A2 CM-I 3.543e-39 0.31
TDT_BOVIN DNTT DNA nucleotidylexotransferase 3.543e-39 0.31
ACER2_HUMAN ACER2 Alkaline ceramidase 2 2.427e-38 0.30
PIN4_HUMAN PIN4 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 1.775e-36 0.29
Q99P97_RAT Histone deacetylase 6 1.948e-36 0.29
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 1.178e-31 0.39
POLH_HUMAN POLH DNA polymerase eta 2.504e-30 0.31
KPCA_BOVIN PRKCA Protein kinase C alpha type 3.649e-24 0.31
PPAF_PHAVU Fe(3+)-Zn(2+) purple acid phosphatase 5.245e-24 0.30
LPAR6_HUMAN LPAR6 Lysophosphatidic acid receptor 6 1.114e-23 0.29
POLK_HUMAN POLK DNA polymerase kappa 1.936e-23 0.31
MGLL_RAT Mgll Monoglyceride lipase 2.716e-20 0.30
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.62e-19 0.32
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 3.514e-19 0.33
K4JQ36_LAOST ace2 Carboxylic ester hydrolase 1.11e-16 0.32
KPCL_MOUSE Prkch Protein kinase C eta type 3.331e-16 0.31
GSHR_PLAF7 GR3 Glutathione reductase 2.343e-13 0.29
LPAR4_HUMAN LPAR4 Lysophosphatidic acid receptor 4 2.343e-13 0.29
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 3.63e-12 0.30
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 3.63e-12 0.30
Q7YWJ9_MUSDO Ache Carboxylic ester hydrolase 6.784e-12 0.32
Q9NJH6_NEPCI AO-AChE Ace-orthologous acetylcholinesterase 6.784e-12 0.32
AGP1_YEAST AGP1 General amino acid permease AGP1 2.465e-11 0.31
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 4.543e-11 0.30
CP74A_ARATH CYP74A Allene oxide synthase, chloroplastic 4.661e-10 0.29
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 5.456e-10 0.31
TNFA_HUMAN TNF Tumor necrosis factor 2.34e-09 0.38
CARP_RHICH Rhizopuspepsin 3.598e-09 0.29
DPOLL_HUMAN POLL DNA polymerase lambda 9.257e-09 0.31
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 4.24e-08 0.37
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 8.972e-08 0.29
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 9.381e-08 0.32
CTRB_BOVIN Chymotrypsinogen B 1.197e-07 0.30
KPCD_MOUSE Prkcd Protein kinase C delta type 3.994e-07 0.29
EST1_RABIT Liver carboxylesterase 1 8.264e-07 0.30
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.09e-06 0.30
CQSS_VIBCH cqsS CAI-1 autoinducer sensor kinase/phosphatase CqsS 1.092e-06 0.28
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 1.507e-06 0.30
DPOLB_RAT Polb DNA polymerase beta 1.595e-06 0.31
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 1.88e-06 0.28
DPOL_VACCW POL DNA polymerase 6.433e-06 0.29
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 7.558e-06 0.32

Rescinnamine

VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 1.451e-45 0.81
ADA2A_PIG ADRA2A Alpha-2A adrenergic receptor 3.819e-39 0.49
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 1.05e-31 0.81
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 2.095e-20 0.81
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.887e-15 0.81
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 4.23e-14 0.49
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.361e-10 0.49
TNR1A_HUMAN TNFRSF1A Tumor necrosis factor receptor superfamily member 1A 1.5e-10 0.34
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 4.853e-10 0.49
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 1.506e-09 0.34
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 1.832e-08 0.81
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.839e-08 0.49
NORA_STAAU norA Quinolone resistance protein NorA 2.334e-08 0.81
ADA2B_RAT Adra2b Alpha-2B adrenergic receptor 1.363e-07 0.49
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 1.245e-06 0.29
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.804e-06 0.36
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 2.562e-06 0.49

Quetiapine

DRD1_HUMAN DRD1 D(1A) dopamine receptor 3.663e-36 0.38
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 2.313e-35 0.39
DRD2_RAT Drd2 D(2) dopamine receptor 6.491e-29 0.98
DRD1_RAT Drd1 D(1A) dopamine receptor 1.497e-25 0.51
LYSC1_RAT Lyz1 Lysozyme C-1 1.908e-25 0.31
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 1.152e-24 0.30
ADRB1_PIG ADRB1 Beta-1 adrenergic receptor 8.749e-23 0.29
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 2.718e-22 0.37
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.082e-21 0.56
BGLR_RAT Gusb Beta-glucuronidase 1.048e-19 0.31
EBPL_HUMAN EBPL Emopamil-binding protein-like 1.048e-19 0.31
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.802e-19 0.44
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.283e-18 0.48
KCNJ3_RAT Kcnj3 G protein-activated inward rectifier potassium channel 1 2.218e-17 0.31
KCNJ5_RAT Kcnj5 G protein-activated inward rectifier potassium channel 4 2.218e-17 0.31
DRD4_RAT Drd4 D(4) dopamine receptor 2.777e-17 0.32
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.22e-17 0.39
DRD5_HUMAN DRD5 D(1B) dopamine receptor 5.107e-15 0.38
HRH1_HUMAN HRH1 Histamine H1 receptor 9.892e-14 0.42
HRH1_RAT Hrh1 Histamine H1 receptor 1.137e-13 0.33
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.92e-13 0.37
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 7.441e-13 0.48
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 5.674e-12 0.29
CALM_BOVIN CALM Calmodulin 1.215e-11 0.31
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 4.856e-11 0.37
B2LA1_MOUSE Bcl2a1 Bcl-2-related protein A1 1.08e-10 0.40
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 3.043e-10 0.33
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 7.414e-10 0.31
DRD4_HUMAN DRD4 D(4) dopamine receptor 9.676e-10 0.48
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 1.955e-09 0.34
CALM1_HUMAN CALM1 Calmodulin-1 7.709e-09 0.31
DDAH1_HUMAN DDAH1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 1.264e-08 0.31
ERG2_YEAST ERG2 C-8 sterol isomerase 3.316e-08 0.31
DRD3_HUMAN DRD3 D(3) dopamine receptor 6.113e-08 0.48
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 6.328e-08 0.55
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.727e-07 0.42
HRH4_HUMAN HRH4 Histamine H4 receptor 2.457e-07 0.51
DRD2_MOUSE Drd2 D(2) dopamine receptor 4.74e-07 0.29
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 4.895e-07 0.31
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 1.819e-06 0.37
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 2.093e-06 0.33
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 3.463e-06 0.32
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 3.547e-06 0.29
WDR48_HUMAN WDR48 WD repeat-containing protein 48 8.695e-06 0.36

Guanethidine

DHYS_RAT Dhps Deoxyhypusine synthase 1.283e-34 0.32
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 2.412e-08 0.30
DPO1_THEAQ polA DNA polymerase I, thermostable 1.418e-07 0.29
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 2.065e-07 0.29
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 2.534e-07 0.29
HRH3_CAVPO HRH3 Histamine H3 receptor 1.79e-06 0.33
Q9V396_DROME CAH1 Carbonic anhydrase 1 2.264e-06 0.41
Q9VTU8_DROME CAH2 Carbonic anhydrase 2, isoform A 2.264e-06 0.41

Chlormezanone

Q9WTR4_RAT Slc6a2 Transporter 8.987e-33 0.35
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 3.941e-22 0.35
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 3.331e-16 0.30
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.332e-15 0.35
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 1.776e-15 0.29
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 9.002e-11 0.44
ACHA9_RAT Chrna9 Neuronal acetylcholine receptor subunit alpha-9 1.441e-10 0.33
LSS_HUMAN LSS Lanosterol synthase 3.963e-09 0.35
PPOC_ORYSJ PPOX1 Protoporphyrinogen oxidase, chloroplastic 7.149e-09 0.30
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 2.734e-07 0.30
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 8.171e-07 0.31
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 1.288e-06 0.33
APJ_HUMAN APLNR Apelin receptor 2.035e-06 0.33
PGH2_BOVIN PTGS2 Prostaglandin G/H synthase 2 2.849e-06 0.29

Phenobarbital

GSHR_PLAF7 GR3 Glutathione reductase 5.314e-26 0.30
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 1.11e-16 0.80
MMP2_HUMAN MMP2 72 kDa type IV collagenase 4.128e-13 0.80
MGAT1_HUMAN MGAT1 Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase 3.82e-12 0.30
MGAT2_MOUSE Mgat2 Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase 4.757e-11 0.30
MMP8_HUMAN MMP8 Neutrophil collagenase 1.581e-09 0.50
MMP13_HUMAN MMP13 Collagenase 3 9.998e-08 0.53
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 1.345e-07 0.30
Q17SB2_PLAFA Plasmepsin 4 2.362e-07 0.29
MGAT3_HUMAN MGAT3 Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase 2.871e-07 0.30

Estazolam

AHR_MOUSE Ahr Aryl hydrocarbon receptor 5.52e-26 0.30
AURKA_MOUSE Aurka Aurora kinase A 2.039e-13 0.29
GBRB3_HUMAN GABRB3 Gamma-aminobutyric acid receptor subunit beta-3 6.345e-13 0.36
GBRG2_HUMAN GABRG2 Gamma-aminobutyric acid receptor subunit gamma-2 1.159e-12 0.36
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 4.081e-11 0.38
GBRA2_HUMAN GABRA2 Gamma-aminobutyric acid receptor subunit alpha-2 3.58e-10 0.62
GBRA4_HUMAN GABRA4 Gamma-aminobutyric acid receptor subunit alpha-4 1.025e-09 0.35
GBRA5_HUMAN GABRA5 Gamma-aminobutyric acid receptor subunit alpha-5 7.728e-09 0.62
GBRA1_HUMAN GABRA1 Gamma-aminobutyric acid receptor subunit alpha-1 9.486e-09 0.62
GBRA3_HUMAN GABRA3 Gamma-aminobutyric acid receptor subunit alpha-3 2.306e-08 0.62
KCNN3_RAT Kcnn3 Small conductance calcium-activated potassium channel protein 3 3.419e-08 0.34
SYMC_HUMAN MARS1 Methionine--tRNA ligase, cytoplasmic 3.827e-08 0.29
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 6.493e-08 0.45
GBRA6_HUMAN GABRA6 Gamma-aminobutyric acid receptor subunit alpha-6 6.613e-07 0.35
TAT_HV112 tat Protein Tat 8.676e-07 0.30
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 1.443e-06 0.31
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 8.283e-06 0.38
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 8.815e-06 0.31

Fomepizole

HEM3_HUMAN HMBS Porphobilinogen deaminase 9.841e-25 0.30

Iodixanol

Q8X6S1_ECO57 nfsA Nitroreductase A 1.834e-18 0.33
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 8.014e-07 0.34

Levetiracetam

MC4R_RAT Mc4r Melanocortin receptor 4 2.887e-15 0.31
MC3R_RAT Mc3r Melanocortin receptor 3 6.772e-15 0.28
CGOX_BACSU cgoX Protoporphyrinogen oxidase 6.271e-10 0.31
O31048_PORGN DPP IV Dipeptidyl peptidase IV 5.832e-08 0.32
DPOLB_RAT Polb DNA polymerase beta 1.317e-06 0.31
TPP2_RAT Tpp2 Tripeptidyl-peptidase 2 7.584e-06 0.31