Results of Job: search_b8216aff-3d96-4c87-9ff3-2b394877cf4e

Query Target Key Target Name Description P-Value MaxTC

compound_1

KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 1.701e-205 0.64
AURKA_HUMAN AURKA Aurora kinase A 1.238e-178 0.64
EGFR_HUMAN EGFR Epidermal growth factor receptor 2.778e-174 0.49
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 6.119e-167 0.49
AURKB_HUMAN AURKB Aurora kinase B 2.7e-96 0.57
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 5.374e-89 0.42
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 2.694e-73 0.37
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 2.047e-69 0.36
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 2.478e-61 0.36
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 3.448e-50 0.37
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 5.949e-50 0.35
C3SLB7_ECOLX glmU Bifunctional protein GlmU 2.147e-49 0.42
DUS2L_HUMAN DUS2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like 9.43e-46 0.36
RXFP1_HUMAN RXFP1 Relaxin receptor 1 5.547e-45 0.33
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 9.659e-43 0.42
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 1.955e-39 0.37
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 9.825e-39 0.36
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 2.189e-37 0.31
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 2.832e-36 0.37
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 8.129e-34 0.33
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 2.04e-31 0.33
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 3.167e-30 0.33
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 1.472e-29 0.36
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 2.334e-29 0.31
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 5.112e-29 0.35
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 3.205e-26 0.30
SHH_MOUSE Shh Sonic hedgehog protein 3.41e-25 0.39
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 2.835e-24 0.33
SENP1_HUMAN SENP1 Sentrin-specific protease 1 4.969e-24 0.31
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 2.341e-23 0.30
ENL_HUMAN MLLT1 Protein ENL 6.794e-23 0.28
AUKBA_XENLA aurkb-a Aurora kinase B-A 2.214e-22 0.36
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 5.031e-21 0.33
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 1.049e-20 0.37
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 2.236e-19 0.34
CD38_MOUSE Cd38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 6.601e-19 0.34
PARG_HUMAN PARG Poly(ADP-ribose) glycohydrolase 7.905e-19 0.30
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 9.387e-19 0.30
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 3.505e-18 0.31
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 4.879e-18 0.29
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 6.608e-18 0.33
AAAT_HUMAN SLC1A5 Neutral amino acid transporter B(0) 1.11e-16 0.32
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 3.331e-16 0.31
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 3.331e-16 0.28
LUCI_RENRE Coelenterazine h 2-monooxygenase 5.551e-16 0.30
CTRO_HUMAN CIT Citron Rho-interacting kinase 2.442e-15 0.31
OPRX_HUMAN OPRL1 Nociceptin receptor 3.664e-15 0.40
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 5.329e-15 0.28
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 1.199e-14 0.33
CSK_HUMAN CSK Tyrosine-protein kinase CSK 8.438e-14 0.30
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 5.532e-13 0.34
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 6.153e-13 0.42
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 1.115e-12 0.30
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 1.921e-12 0.30
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 2.122e-12 0.37
SHIP2_HUMAN INPPL1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 4.114e-12 0.30
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 4.981e-12 0.36
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 1.047e-11 0.33
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1.767e-11 0.30
TPOR_HUMAN MPL Thrombopoietin receptor 1.986e-11 0.30
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 3.707e-11 0.31
LYOX_HUMAN LOX Protein-lysine 6-oxidase 5.451e-11 0.29
Q9Z1J7_RAT Slc1a5 Amino acid transporter 7.648e-11 0.32
TXK_HUMAN TXK Tyrosine-protein kinase TXK 8.061e-11 0.31
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 8.637e-11 0.29
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 9.001e-11 0.29
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 9.486e-11 0.30
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.018e-10 0.31
INSR_HUMAN INSR Insulin receptor 1.396e-10 0.42
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 1.668e-10 0.29
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 2.737e-10 0.36
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 3.094e-10 0.29
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 3.765e-10 0.29
NR1H4_HUMAN NR1H4 Bile acid receptor 5.017e-10 0.33
MET_HUMAN MET Hepatocyte growth factor receptor 6.132e-10 0.36
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 6.31e-10 0.36
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 8.42e-10 0.35
SCAF_HCMVA UL80 Capsid scaffolding protein 9.384e-10 0.36
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 1.08e-09 0.30
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 1.222e-09 0.30
DMPK_HUMAN DMPK Myotonin-protein kinase 1.414e-09 0.30
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 1.86e-09 0.33
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 2.234e-09 0.29
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 2.392e-09 0.30
SMO_HUMAN SMO Smoothened homolog 2.436e-09 0.39
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 2.728e-09 0.34
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2.883e-09 0.31
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 3.624e-09 0.30
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 4.706e-09 0.30
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 6.885e-09 0.34
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 9.659e-09 0.30
ST32B_HUMAN STK32B Serine/threonine-protein kinase 32B 1.123e-08 0.29
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 1.575e-08 0.36
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.68e-08 0.36
GAK_HUMAN GAK Cyclin-G-associated kinase 1.77e-08 0.31
HPSE_HUMAN HPSE Heparanase 1.773e-08 0.30
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 2.163e-08 0.30
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 2.328e-08 0.42
HDAC1_HUMAN HDAC1 Histone deacetylase 1 2.359e-08 0.39
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 2.46e-08 0.42
PTGES_HUMAN PTGES Prostaglandin E synthase 2.667e-08 0.34
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 3.403e-08 0.35
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 4.349e-08 0.30
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 4.391e-08 0.33
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 8.925e-08 0.29
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 9.403e-08 0.29
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 1.17e-07 0.30
O68720_YERPE yopH Targeted effector protein 1.486e-07 0.29
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 1.569e-07 0.33
CDK16_HUMAN CDK16 Cyclin-dependent kinase 16 1.599e-07 0.29
PDE5A_BOVIN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 1.788e-07 0.29
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 1.909e-07 0.29
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 1.909e-07 0.29
PD1L1_HUMAN CD274 Programmed cell death 1 ligand 1 1.995e-07 0.29
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 2.006e-07 0.39
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 2.164e-07 0.29
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 2.571e-07 0.31
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 2.626e-07 0.30
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 3.352e-07 0.30
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 3.614e-07 0.32
LCK_HUMAN LCK Tyrosine-protein kinase Lck 3.93e-07 0.43
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 4.514e-07 0.29
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 4.537e-07 0.33
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 4.55e-07 0.37
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 4.943e-07 0.33
AOFB_RAT Maob Amine oxidase [flavin-containing] B 7.644e-07 0.33
PRIO_SHEEP PRNP Major prion protein 7.696e-07 0.32
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 8.296e-07 0.29
HDAC3_HUMAN HDAC3 Histone deacetylase 3 9.16e-07 0.39
AAK1_HUMAN AAK1 AP2-associated protein kinase 1 9.656e-07 0.29
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 9.685e-07 0.35
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 1.398e-06 0.29
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 1.517e-06 0.30
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 1.557e-06 0.30
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 2.392e-06 0.30
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 2.54e-06 0.29
AURKC_HUMAN AURKC Aurora kinase C 2.592e-06 0.29
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 2.849e-06 0.29
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 3.191e-06 0.31
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 3.355e-06 0.28
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 3.396e-06 0.30
PDE11_HUMAN PDE11A Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 3.948e-06 0.29
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 4.014e-06 0.30
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 4.115e-06 0.29
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 4.283e-06 0.29
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 4.483e-06 0.34
E2AK4_HUMAN EIF2AK4 eIF-2-alpha kinase GCN2 4.584e-06 0.29
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 5.205e-06 0.29
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 6.172e-06 0.31
INSRR_HUMAN INSRR Insulin receptor-related protein 6.392e-06 0.29
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 6.392e-06 0.29
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 7.451e-06 0.35
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 8.268e-06 0.30
SKN1_CAEEL skn-1 Protein skinhead-1 9.25e-06 0.35