Results of Job: search_c20bc640-d90d-435b-b78b-2b5c690d9bc0

Query Target Key Target Name Description P-Value MaxTC

compound_1

KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 3.131e-125 0.53
AURKA_HUMAN AURKA Aurora kinase A 6.241e-121 0.53
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 7.834e-106 0.41
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 9.16e-87 0.43
CTNB1_HUMAN CTNNB1 Catenin beta-1 5.167e-80 0.43
EGFR_HUMAN EGFR Epidermal growth factor receptor 1.236e-71 0.45
AURKB_HUMAN AURKB Aurora kinase B 5.944e-71 0.53
SENP1_HUMAN SENP1 Sentrin-specific protease 1 9.706e-56 0.34
ERBB2_RAT Erbb2 Receptor tyrosine-protein kinase erbB-2 9.769e-52 0.32
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 6.164e-49 0.41
Q9FD53_STREE mvaD Diphosphomevalonate decarboxylase 7.218e-47 0.39
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 1.412e-45 0.42
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.492e-45 0.43
SENP2_HUMAN SENP2 Sentrin-specific protease 2 1.157e-39 0.31
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 3.444e-39 0.43
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.759e-38 0.34
E2AK3_RAT Eif2ak3 Eukaryotic translation initiation factor 2-alpha kinase 3 6.694e-38 0.30
SHH_MOUSE Shh Sonic hedgehog protein 1.511e-37 0.42
PGDA2_BACCR Peptidoglycan-N-acetylglucosamine deacetylase BC_1974 1.948e-36 0.29
PDS_SYNE7 pds 15-cis-phytoene desaturase 4.87e-36 0.31
KLKB1_HUMAN KLKB1 Plasma kallikrein 6.409e-36 0.33
STABP_HUMAN STAMBP STAM-binding protein 4.271e-34 0.33
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 5.141e-34 0.38
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 4.269e-33 0.42
VE1_HPV11 E1 Replication protein E1 2.45e-30 0.38
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 3.22e-30 0.44
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.342e-27 0.37
ARBK1_HUMAN GRK2 Beta-adrenergic receptor kinase 1 1.995e-27 0.36
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 1.119e-26 0.33
ACOD1_MOUSE Scd1 Acyl-CoA desaturase 1 1.405e-24 0.35
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 1.112e-23 0.39
HDAC1_HUMAN HDAC1 Histone deacetylase 1 4.301e-23 0.40
NR1H4_HUMAN NR1H4 Bile acid receptor 8.488e-23 0.41
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.631e-22 0.43
AUKBA_XENLA aurkb-a Aurora kinase B-A 2.174e-22 0.36
HDAC6_HUMAN HDAC6 Histone deacetylase 6 6.594e-22 0.46
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.694e-21 0.38
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 5.619e-21 0.32
MMP13_MOUSE Mmp13 Collagenase 3 5.759e-21 0.32
EGFR_MOUSE Egfr Epidermal growth factor receptor 7.678e-21 0.32
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 9.791e-21 0.41
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 2.318e-20 0.32
TERA_HUMAN VCP Transitional endoplasmic reticulum ATPase 3.085e-20 0.32
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 1.048e-19 0.31
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 2.15e-19 0.32
HGFL_HUMAN MST1 Hepatocyte growth factor-like protein 2.677e-19 0.31
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 1.078e-18 0.40
PADI6_HUMAN PADI6 Protein-arginine deiminase type-6 1.372e-18 0.29
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 3.546e-18 0.30
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 1.229e-17 0.44
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 1.346e-17 0.50
PDE4B_HUMAN PDE4B cAMP-specific 3',5'-cyclic phosphodiesterase 4B 1.381e-17 0.36
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 1.463e-17 0.33
GLUC_HUMAN GCG Glucagon 2.976e-17 0.31
RFA1_HUMAN RPA1 Replication protein A 70 kDa DNA-binding subunit 4.478e-17 0.36
E1BN64_BOVIN PDE3B Phosphodiesterase 1.11e-16 0.29
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 1.11e-16 0.31
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 2.22e-16 0.31
AA1R_BOVIN ADORA1 Adenosine receptor A1 3.331e-16 0.38
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 2.665e-15 0.29
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 2.998e-15 0.38
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 3.109e-15 0.40
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 5.551e-15 0.33
ARBK2_HUMAN GRK3 Beta-adrenergic receptor kinase 2 1.366e-14 0.36
DYR_ENTFC folA Dihydrofolate reductase 1.876e-14 0.29
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 2.132e-14 0.34
HDAC8_HUMAN HDAC8 Histone deacetylase 8 2.331e-14 0.46
ACOD_HUMAN SCD Acyl-CoA desaturase 7.45e-14 0.35
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 1.231e-13 0.41
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 2.226e-13 0.33
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 2.479e-13 0.41
Q76129_9HIV1 gag Structural capsid protein 3.261e-13 0.37
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 4.778e-13 0.33
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 6.156e-13 0.32
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 6.88e-13 0.36
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 1.594e-12 0.37
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 1.854e-12 0.32
LYOX_HUMAN LOX Protein-lysine 6-oxidase 1.941e-12 0.35
HDAC3_HUMAN HDAC3 Histone deacetylase 3 2.134e-12 0.40
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 2.141e-12 0.37
MMP13_HUMAN MMP13 Collagenase 3 2.861e-12 0.44
HDAC2_HUMAN HDAC2 Histone deacetylase 2 3.086e-12 0.46
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 3.463e-12 0.38
PRIO_SHEEP PRNP Major prion protein 6.684e-12 0.29
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 9.56e-12 0.32
NCOA1_HUMAN NCOA1 Nuclear receptor coactivator 1 1.027e-11 0.32
RS27_HUMAN RPS27 40S ribosomal protein S27 1.615e-11 0.31
TPH1_HUMAN TPH1 Tryptophan 5-hydroxylase 1 1.627e-11 0.32
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 1.627e-11 0.37
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 1.664e-11 0.35
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 2.088e-11 0.34
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 2.566e-11 0.32
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 2.983e-11 0.29
STAT3_MOUSE Stat3 Signal transducer and activator of transcription 3 3.472e-11 0.30
CD38_MOUSE Cd38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 6.729e-11 0.34
AMP1_PLAFQ M1 family aminopeptidase 8.85e-11 0.31
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 9.45e-11 0.41
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 9.762e-11 0.37
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.336e-10 0.32
VP16_HHV11 Tegument protein VP16 1.349e-10 0.32
DCTP1_HUMAN DCTPP1 dCTP pyrophosphatase 1 1.432e-10 0.36
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 1.508e-10 0.40
CCNK_HUMAN CCNK Cyclin-K 1.675e-10 0.28
KLK1_HUMAN KLK1 Kallikrein-1 2.001e-10 0.32
LUCI_RENRE Coelenterazine h 2-monooxygenase 2.824e-10 0.37
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 2.875e-10 0.35
USP_DROME usp Protein ultraspiracle 3.214e-10 0.30
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 3.499e-10 0.32
IF4E_HUMAN EIF4E Eukaryotic translation initiation factor 4E 4.146e-10 0.33
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 5.162e-10 0.29
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 6.354e-10 0.35
ACES_TETCF ache Acetylcholinesterase 6.48e-10 0.30
SCN3A_HUMAN SCN3A Sodium channel protein type 3 subunit alpha 7.135e-10 0.38
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 7.574e-10 0.36
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 1.064e-09 0.34
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 1.143e-09 0.36
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 1.326e-09 0.34
MTSI_SPISQ sssIM CPG DNA methylase 1.37e-09 0.30
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 1.503e-09 0.39
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 1.649e-09 0.30
THRB_HUMAN F2 Prothrombin 2.098e-09 0.35
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 2.198e-09 0.35
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 2.456e-09 0.33
ECR_BOMMO EcR Ecdysone receptor 2.578e-09 0.30
PANC_MYCTU panC Pantothenate synthetase 2.603e-09 0.36
IMPA1_BOVIN IMPA1 Inositol monophosphatase 1 2.714e-09 0.31
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 3.346e-09 0.28
ASAH1_HUMAN ASAH1 Acid ceramidase 3.445e-09 0.31
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 3.775e-09 0.39
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 4.217e-09 0.30
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 5.984e-09 0.41
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 7.332e-09 0.36
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 8.97e-09 0.30
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 9.357e-09 0.33
A5H660_SCHMA HDAC8 Histone deacetylase 8 9.443e-09 0.34
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 1.11e-08 0.36
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 1.153e-08 0.37
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 1.318e-08 0.35
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.386e-08 0.37
TRY1_RAT Prss1 Anionic trypsin-1 1.701e-08 0.29
UPAR_RAT Plaur Urokinase plasminogen activator surface receptor 1.701e-08 0.29
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 1.751e-08 0.36
CATL1_BOVIN CTSL Cathepsin L1 1.83e-08 0.29
ECR_DROME EcR Ecdysone receptor 1.906e-08 0.30
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 2.423e-08 0.33
PPAP_HUMAN ACP3 Prostatic acid phosphatase 2.437e-08 0.31
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 3.242e-08 0.37
TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 3.308e-08 0.33
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 3.497e-08 0.31
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 3.793e-08 0.36
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 4.697e-08 0.38
IL6_HUMAN IL6 Interleukin-6 5.175e-08 0.31
AA3R_HUMAN ADORA3 Adenosine receptor A3 5.392e-08 0.37
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 5.603e-08 0.33
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 5.703e-08 0.36
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 6.315e-08 0.37
EGLN1_HUMAN EGLN1 Egl nine homolog 1 6.511e-08 0.36
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 7.584e-08 0.36
CASP1_HUMAN CASP1 Caspase-1 1.095e-07 0.39
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 1.163e-07 0.36
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 1.27e-07 0.36
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 1.535e-07 0.30
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 1.583e-07 0.28
E3UJZ5_SPOLI Ecdysone receptor 1.627e-07 0.29
XPA_HUMAN XPA DNA repair protein complementing XP-A cells 1.631e-07 0.29
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 1.659e-07 0.32
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 1.912e-07 0.33
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 2.034e-07 0.33
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 2.272e-07 0.31
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 2.285e-07 0.31
O97467_PLAFA ht1 Hexose transporter 1 2.727e-07 0.33
O61059_LEIME LmGT2 Glucose transporter 2.807e-07 0.33
AA1R_CHICK ADORA1 Adenosine receptor A1 2.925e-07 0.28
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 2.928e-07 0.41
PRKX_HUMAN PRKX cAMP-dependent protein kinase catalytic subunit PRKX 2.969e-07 0.44
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 3.083e-07 0.28
FA7_HUMAN F7 Coagulation factor VII 3.147e-07 0.31
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 3.217e-07 0.37
PA_I34A1 PA Polymerase acidic protein 3.283e-07 0.30
SCAF_HCMVA UL80 Capsid scaffolding protein 3.398e-07 0.30
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 4.215e-07 0.33
HDAC5_HUMAN HDAC5 Histone deacetylase 5 4.269e-07 0.32
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 4.486e-07 0.44
HDAC7_HUMAN HDAC7 Histone deacetylase 7 5.07e-07 0.32
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 5.094e-07 0.32
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 5.366e-07 0.36
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 5.466e-07 0.33
Q6FTL6_CANGA NCE103 Carbonic anhydrase 5.471e-07 0.31
AA3R_RAT Adora3 Adenosine receptor A3 5.912e-07 0.31
ACK1_MOUSE Tnk2 Activated CDC42 kinase 1 6.058e-07 0.29
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 7.018e-07 0.37
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 7.293e-07 0.33
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 7.447e-07 0.29
SENP7_HUMAN SENP7 Sentrin-specific protease 7 7.968e-07 0.38
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 7.997e-07 0.34
AA1R_HUMAN ADORA1 Adenosine receptor A1 8.117e-07 0.37
GYRB_MYCS2 gyrB DNA gyrase subunit B 8.547e-07 0.29
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 8.989e-07 0.31
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 9.053e-07 0.35
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 9.919e-07 0.37
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 1.186e-06 0.33
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 1.346e-06 0.32
AA1R_RAT Adora1 Adenosine receptor A1 1.483e-06 0.34
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 1.538e-06 0.34
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1.825e-06 0.36
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.858e-06 0.28
PEPT1_DERPT DERP1 Peptidase 1 1.874e-06 0.29
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 1.969e-06 0.31
Q76353_9HIV1 Integrase 2.125e-06 0.32
LCK_HUMAN LCK Tyrosine-protein kinase Lck 2.166e-06 0.36
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 2.346e-06 0.30
CAH2_BOVIN CA2 Carbonic anhydrase 2 2.559e-06 0.37
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 2.654e-06 0.46
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 2.725e-06 0.39
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 2.845e-06 0.30
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 2.908e-06 0.33
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 3.171e-06 0.29
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 3.332e-06 0.32
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 3.374e-06 0.34
PRIO_MESAU PRNP Major prion protein 3.409e-06 0.28
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 4.106e-06 0.30
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 4.371e-06 0.40
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 4.586e-06 0.30
TF_HUMAN F3 Tissue factor 4.974e-06 0.30
AGTR1_HUMAN AGTR1 Type-1 angiotensin II receptor 5.771e-06 0.35
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 5.913e-06 0.44
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 6.308e-06 0.30
SCNAA_HUMAN SCN10A Sodium channel protein type 10 subunit alpha 6.399e-06 0.37
LUCI_AQULA Luciferin 4-monooxygenase 6.433e-06 0.29
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 7.305e-06 0.29
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 7.409e-06 0.33
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 8.231e-06 0.44
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 8.415e-06 0.34
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 8.689e-06 0.33
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 8.689e-06 0.33