Results of Job: search_c518683e-e0ee-4b82-854a-451087714e44

Query Target Key Target Name Description P-Value MaxTC

Latanoprost_acid

PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 2.78e-184 1.00
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 1.908e-114 1.00
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 4.705e-101 1.00
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 4.662e-174 0.77
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 1.664e-70 0.48
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 2.826e-63 0.51
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 1.756e-61 0.49
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 6.997e-53 0.54
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 1.024e-47 0.32
MMP12_HUMAN MMP12 Macrophage metalloelastase 1.258e-39 0.38
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 3.278e-38 0.48
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 7.015e-34 0.43
MMP10_HUMAN MMP10 Stromelysin-2 1.675e-31 0.33
Q9NAW4_PLAFA Cysteine protease falcipain-3 8.722e-30 0.32
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 3.353e-29 0.68
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 4.001e-29 0.73
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 7.863e-25 0.43
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 8.658e-24 0.43
PE2R4_RABIT PTGER4 Prostaglandin E2 receptor EP4 subtype 5.518e-23 0.28
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 1.164e-20 0.43
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 1.954e-19 0.48
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 3.562e-19 0.73
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 4.11e-19 0.30
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 7.436e-19 0.50
CBPA1_BOVIN CPA1 Carboxypeptidase A1 1.11e-16 0.33
MMP8_HUMAN MMP8 Neutrophil collagenase 1.11e-16 0.33
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 3.331e-16 0.31
LY96_HUMAN LY96 Lymphocyte antigen 96 9.992e-16 0.30
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.11e-15 0.30
PI2R_HUMAN PTGIR Prostacyclin receptor 1.321e-14 0.45
TA2R_RAT Tbxa2r Thromboxane A2 receptor 5.373e-14 0.44
LOX15_PIG ALOX15 Arachidonate 15-lipoxygenase 1.741e-13 0.30
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 4.344e-13 0.37
NEP_MOUSE Mme Neprilysin 6.108e-13 0.28
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 1.365e-12 0.36
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.448e-12 0.37
DLG4_HUMAN DLG4 Disks large homolog 4 1.466e-12 0.32
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.5e-12 0.46
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 1.905e-12 0.31
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 3.736e-12 0.31
MMP3_HUMAN MMP3 Stromelysin-1 9.582e-12 0.34
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 2.117e-11 0.39
AMPL_PIG LAP3 Cytosol aminopeptidase 6.673e-10 0.28
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 2.094e-09 0.30
AMPN_HUMAN ANPEP Aminopeptidase N 2.274e-09 0.32
PPCE_BOVIN PREP Prolyl endopeptidase 4.099e-09 0.28
MMP2_HUMAN MMP2 72 kDa type IV collagenase 5.477e-09 0.38
NEP_RABIT MME Neprilysin 6.53e-09 0.33
MMP13_HUMAN MMP13 Collagenase 3 1.396e-08 0.38
ACE_HUMAN ACE Angiotensin-converting enzyme 3.705e-08 0.31
CLTR1_CAVPO CYSLTR1 Cysteinyl leukotriene receptor 1 4.902e-08 0.37
ACE_RABIT ACE Angiotensin-converting enzyme 5.017e-08 0.32
NEP_RAT Mme Neprilysin 9.647e-08 0.33
Q6UB75_PIG Group VII phospholipase A2 1.445e-07 0.31
CASP1_HUMAN CASP1 Caspase-1 2.349e-07 0.33
HDA11_HUMAN HDAC11 Histone deacetylase 11 3.049e-07 0.33
CBPA1_HUMAN CPA1 Carboxypeptidase A1 4.892e-07 0.28
ACE_MOUSE Ace Angiotensin-converting enzyme 6.148e-07 0.28
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 7.508e-07 0.34
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 9.501e-07 0.31
CNR1_RAT Cnr1 Cannabinoid receptor 1 9.906e-07 0.43
RIR1_HHV11 RIR1 Ribonucleoside-diphosphate reductase large subunit 1.507e-06 0.30
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 1.554e-06 0.33
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 2.592e-06 0.28
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 4.823e-06 0.30
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 6.077e-06 0.33

Gozetotide

FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 1.114e-118 1.00
TYSY_MOUSE Tyms Thymidylate synthase 1.061e-99 0.33
PUR2_HUMAN GART Trifunctional purine biosynthetic protein adenosine-3 3.986e-81 0.34
GRIA1_RAT Gria1 Glutamate receptor 1 4.979e-69 0.32
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 1.131e-62 0.42
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 2.225e-54 0.35
TYSY_RAT Tyms Thymidylate synthase 8.979e-53 0.29
MMP12_HUMAN MMP12 Macrophage metalloelastase 1.966e-52 0.35
TYSY_HUMAN TYMS Thymidylate synthase 3.539e-52 0.33
TYTR_CRIFA TPR Trypanothione reductase 1.318e-50 0.40
MMP10_HUMAN MMP10 Stromelysin-2 2.889e-49 0.35
PSB6_YEAST PRE7 Proteasome subunit beta type-6 1.718e-42 0.34
DLG4_HUMAN DLG4 Disks large homolog 4 3.026e-40 0.33
Q9I056_PSEAE cpg2 Carboxypeptidase G2 1.37e-37 0.29
Q99P97_RAT Histone deacetylase 6 1.332e-36 0.29
PUR2_MOUSE Gart Trifunctional purine biosynthetic protein adenosine-3 4.458e-35 0.31
DYR_MOUSE Dhfr Dihydrofolate reductase 6.015e-35 0.33
HDAC1_RAT Hdac1 Histone deacetylase 1 2.137e-33 0.29
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 3.154e-28 0.39
FOLC_MOUSE Fpgs Folylpolyglutamate synthase, mitochondrial 3.237e-28 0.30
TYSY_LACCA thyA Thymidylate synthase 3.64e-27 0.33
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 9.771e-27 0.36
MMP8_HUMAN MMP8 Neutrophil collagenase 4.082e-26 0.35
GRIA1_HUMAN GRIA1 Glutamate receptor 1 8.418e-26 0.35
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 8.859e-26 0.29
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 8.859e-26 0.29
FOLR2_HUMAN FOLR2 Folate receptor beta 2.114e-25 0.30
GASR_BOVIN CCKBR Gastrin/cholecystokinin type B receptor 2.306e-24 0.29
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 1.905e-22 0.35
PCFT_HUMAN SLC46A1 Proton-coupled folate transporter 7.478e-22 0.30
PSB5_YEAST PRE2 Proteasome subunit beta type-5 3.889e-21 0.34
DYR_ENTFC folA Dihydrofolate reductase 1.551e-20 0.33
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2.025e-20 0.33
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 3.36e-19 0.31
IDE_HUMAN IDE Insulin-degrading enzyme 6.181e-19 0.36
RIR1_MYCTU nrdE Ribonucleoside-diphosphate reductase subunit alpha 1.265e-18 0.30
DYR_HUMAN DHFR Dihydrofolate reductase 1.417e-18 0.33
NEC2_HUMAN PCSK2 Neuroendocrine convertase 2 1.664e-18 0.29
FURIN_HUMAN FURIN Furin 1.826e-18 0.33
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 1.858e-18 0.29
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 1.97e-18 0.36
GNPAT_HUMAN GNPAT Dihydroxyacetone phosphate acyltransferase 2.749e-18 0.29
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 1.766e-17 0.40
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 1.858e-17 0.30
DYR_LACCA folA Dihydrofolate reductase 1.11e-16 0.30
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 1.11e-16 0.39
LY96_HUMAN LY96 Lymphocyte antigen 96 1.11e-16 0.32
FOLR1_HUMAN FOLR1 Folate receptor alpha 9.992e-16 0.30
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 8.216e-15 0.35
PCSK6_HUMAN PCSK6 Proprotein convertase subtilisin/kexin type 6 1.055e-14 0.30
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 1.108e-13 0.32
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.166e-13 0.37
S19A1_HUMAN SLC19A1 Reduced folate transporter 1.716e-13 0.29
PCSK7_HUMAN PCSK7 Proprotein convertase subtilisin/kexin type 7 1.815e-13 0.29
PTN2_HUMAN PTPN2 Tyrosine-protein phosphatase non-receptor type 2 5.087e-13 0.37
MMP2_HUMAN MMP2 72 kDa type IV collagenase 1.35e-12 0.35
TLR2_HUMAN TLR2 Toll-like receptor 2 2.377e-12 0.30
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 1.92e-11 0.31
MMP3_HUMAN MMP3 Stromelysin-1 2.508e-11 0.36
MMP13_HUMAN MMP13 Collagenase 3 4.821e-11 0.35
E2QDN0_ECOLX thyA Thymidylate synthase 6.878e-11 0.29
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2.759e-10 0.36
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 3.906e-10 0.37
DYR_RAT Dhfr Dihydrofolate reductase 1.127e-09 0.33
POLG_WNV Genome polyprotein 1.862e-09 0.31
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 3.369e-09 0.28
TYTR_TRYCR TPR Trypanothione reductase 5.55e-09 0.40
ELAS_PSEAE lasB Elastase 5.969e-09 0.29
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 7.889e-09 0.36
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 4.085e-08 0.29
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 4.67e-08 0.32
OPRD_MOUSE Oprd1 Delta-type opioid receptor 6.268e-08 0.31
CMA1_HUMAN CMA1 Chymase 6.356e-08 0.31
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.164e-07 0.37
OPRM_CAVPO OPRM1 Mu-type opioid receptor 2.318e-07 0.31
GRIA3_HUMAN GRIA3 Glutamate receptor 3 2.396e-07 0.31
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 2.522e-07 0.32
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 3.07e-07 0.28
Q6UB75_PIG Group VII phospholipase A2 3.447e-07 0.29
TYSY_ECOLI thyA Thymidylate synthase 5.846e-07 0.29
HDA11_HUMAN HDAC11 Histone deacetylase 11 5.948e-07 0.32
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 9.324e-07 0.32
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 1.318e-06 0.29
MC3R_HUMAN MC3R Melanocortin receptor 3 1.323e-06 0.32
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 1.942e-06 0.33
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.995e-06 0.28
C3SWJ7_ECOLX thyA Thymidylate synthase 2.368e-06 0.29
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 2.376e-06 0.29
CBX7_HUMAN CBX7 Chromobox protein homolog 7 2.418e-06 0.28
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 3.621e-06 0.29
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 3.692e-06 0.31
PTPRA_HUMAN PTPRA Receptor-type tyrosine-protein phosphatase alpha 4.044e-06 0.34
NK2R_MESAU TACR2 Substance-K receptor 4.78e-06 0.30
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 4.975e-06 0.32
CAH4_BOVIN CA4 Carbonic anhydrase 4 6.395e-06 0.36
PSA1_HUMAN PSMA1 Proteasome subunit alpha type-1 9.136e-06 0.31
PSA2_HUMAN PSMA2 Proteasome subunit alpha type-2 9.136e-06 0.31
PSA3_HUMAN PSMA3 Proteasome subunit alpha type-3 9.136e-06 0.31
PSA4_HUMAN PSMA4 Proteasome subunit alpha type-4 9.136e-06 0.31
PSA5_HUMAN PSMA5 Proteasome subunit alpha type-5 9.136e-06 0.31
PSA6_HUMAN PSMA6 Proteasome subunit alpha type-6 9.136e-06 0.31
PSA7_HUMAN PSMA7 Proteasome subunit alpha type-7 9.136e-06 0.31
PSB11_HUMAN PSMB11 Proteasome subunit beta type-11 9.136e-06 0.31
PSB3_HUMAN PSMB3 Proteasome subunit beta type-3 9.136e-06 0.31
PSB4_HUMAN PSMB4 Proteasome subunit beta type-4 9.136e-06 0.31
PSB6_HUMAN PSMB6 Proteasome subunit beta type-6 9.136e-06 0.31
PSB7_HUMAN PSMB7 Proteasome subunit beta type-7 9.136e-06 0.31
PSMA8_HUMAN PSMA8 Proteasome subunit alpha-type 8 9.136e-06 0.31

Acoramidis

TTHY_HUMAN TTR Transthyretin 2.875e-21 1.00
HAOX2_RAT Hao2 Hydroxyacid oxidase 2 9.025e-141 0.42
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 5.093e-64 0.40
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 2.766e-42 0.34
HAOX2_HUMAN HAO2 Hydroxyacid oxidase 2 5.881e-40 0.32
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 9.027e-38 0.37
MAX_HUMAN MAX Protein max 1.023e-37 0.30
PKR1_HUMAN PROKR1 Prokineticin receptor 1 6.692e-37 0.34
P4HA1_HUMAN P4HA1 Prolyl 4-hydroxylase subunit alpha-1 1.464e-36 0.30
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 2.964e-35 0.40
RARB_HUMAN RARB Retinoic acid receptor beta 7.547e-31 0.36
GRM3_RAT Grm3 Metabotropic glutamate receptor 3 1.504e-30 0.40
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 8.447e-30 0.35
KDM5A_HUMAN KDM5A Lysine-specific demethylase 5A 4.671e-26 0.34
KDM5B_HUMAN KDM5B Lysine-specific demethylase 5B 5.772e-24 0.34
KDM2B_HUMAN KDM2B Lysine-specific demethylase 2B 1.037e-22 0.32
HCAR2_RAT Hcar2 Hydroxycarboxylic acid receptor 2 2.715e-22 0.32
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 1.426e-20 0.32
UNG_HUMAN UNG Uracil-DNA glycosylase 3.122e-19 0.31
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 7.918e-19 0.32
PA24A_HUMAN PLA2G4A Cytosolic phospholipase A2 1.672e-18 0.34
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 1.728e-18 0.35
RARA_HUMAN RARA Retinoic acid receptor alpha 2.844e-18 0.33
RARG_HUMAN RARG Retinoic acid receptor gamma 8.846e-18 0.35
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 3.331e-16 0.36
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 7.772e-16 0.29
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 2.776e-15 0.38
HNF4A_RAT Hnf4a Hepatocyte nuclear factor 4-alpha 9.992e-15 0.30
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 1.021e-14 0.29
ALBU_HUMAN ALB Serum albumin 4.086e-14 0.32
CP26B_HUMAN CYP26B1 Cytochrome P450 26B1 2.002e-13 0.30
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 2.932e-13 0.33
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 3.531e-13 0.32
HNF4A_HUMAN HNF4A Hepatocyte nuclear factor 4-alpha 5.639e-12 0.30
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 6.966e-12 0.29
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 9.399e-12 0.32
KMO_MOUSE Kmo Kynurenine 3-monooxygenase 1.508e-11 0.28
RXRA_HUMAN RXRA Retinoic acid receptor RXR-alpha 4.638e-11 0.33
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 5.018e-11 0.30
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 1.203e-10 0.30
FA5_HUMAN F5 Coagulation factor V 1.272e-10 0.28
FFAR4_MOUSE Ffar4 Free fatty acid receptor 4 3.211e-10 0.33
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 7.484e-10 0.30
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 1.271e-09 0.33
KMO_HUMAN KMO Kynurenine 3-monooxygenase 1.404e-09 0.31
P2RX1_MOUSE P2rx1 P2X purinoceptor 1 3.055e-09 0.29
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 4.251e-08 0.31
CLTR2_HUMAN CYSLTR2 Cysteinyl leukotriene receptor 2 4.324e-08 0.36
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 8.535e-08 0.32
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.282e-07 0.32
KMO_RAT Kmo Kynurenine 3-monooxygenase 1.999e-07 0.29
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 2.19e-07 0.42
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 3.564e-07 0.33
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 3.722e-07 0.30
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 6.482e-07 0.30
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 1.032e-06 0.28
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.089e-06 0.31
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 1.34e-06 0.36
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 1.645e-06 0.35
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.936e-06 0.36
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 2.168e-06 0.29
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 2.405e-06 0.29
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 2.624e-06 0.32
ENV_HV1Y2 env Envelope glycoprotein gp160 2.735e-06 0.38
HRH3_RAT Hrh3 Histamine H3 receptor 2.894e-06 0.36
THA_HUMAN THRA Thyroid hormone receptor alpha 5.354e-06 0.34
KDM4B_HUMAN KDM4B Lysine-specific demethylase 4B 7.664e-06 0.30
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 7.664e-06 0.33
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 7.705e-06 0.28

Acoltremon

TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 0.0011 1.00
ELOV6_HUMAN ELOVL6 Elongation of very long chain fatty acids protein 6 1.607e-61 0.45
NPBW1_MOUSE Npbwr1 Neuropeptides B/W receptor type 1 7.597e-40 0.31
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 1.777e-36 0.58
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 2.695e-35 0.38
KCNQ1_HUMAN KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 8.455e-31 0.30
MMP7_HUMAN MMP7 Matrilysin 3.484e-25 0.32
ELOV3_MOUSE Elovl3 Elongation of very long chain fatty acids protein 3 2.814e-22 0.36
PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 7.773e-22 0.44
MMP13_RAT Mmp13 Collagenase 3 9.235e-22 0.32
MMP1_HUMAN MMP1 Interstitial collagenase 5.202e-21 0.35
MECP2_HUMAN MECP2 Methyl-CpG-binding protein 2 3.184e-20 0.32
MMP3_HUMAN MMP3 Stromelysin-1 2.298e-19 0.32
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 4.354e-19 0.35
PYRD_RAT Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 7.581e-19 0.44
F261_HUMAN PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 9.95e-18 0.30
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 2.985e-17 0.45
Q8IL11_PLAF7 M17 leucyl aminopeptidase 3.331e-16 0.42
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 1.554e-15 0.35
HDAC8_HUMAN HDAC8 Histone deacetylase 8 2.665e-15 0.36
PPAP_HUMAN ACP3 Prostatic acid phosphatase 5.107e-15 0.29
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 5.551e-15 0.31
DLDH_MYCTU lpdC Dihydrolipoyl dehydrogenase 6.384e-14 0.39
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 8.249e-14 0.36
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 1.044e-13 0.57
ECR_AEDAE EcR Ecdysone receptor 1.915e-13 0.33
MMP13_HUMAN MMP13 Collagenase 3 3.252e-13 0.35
MMP2_HUMAN MMP2 72 kDa type IV collagenase 6.499e-13 0.35
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 1.594e-12 0.38
F1SH20_PIG TRHDE Uncharacterized protein 1.741e-12 0.34
ITA3_HUMAN ITGA3 Integrin alpha-3 4.2e-12 0.30
ELOV6_MOUSE Elovl6 Elongation of very long chain fatty acids protein 6 4.412e-12 0.36
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 8.482e-12 0.34
TRPC6_HUMAN TRPC6 Short transient receptor potential channel 6 1.91e-11 0.37
ELOV3_HUMAN ELOVL3 Elongation of very long chain fatty acids protein 3 3.081e-11 0.36
F262_HUMAN PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 4.627e-11 0.30
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 7.946e-11 0.29
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 8.833e-11 0.38
TRPC3_HUMAN TRPC3 Short transient receptor potential channel 3 2.312e-10 0.37
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 3.64e-10 0.43
ACRO_HUMAN ACR Acrosin 3.705e-10 0.35
MMP8_HUMAN MMP8 Neutrophil collagenase 4.225e-10 0.32
GLP1R_RAT Glp1r Glucagon-like peptide 1 receptor 8.149e-10 0.31
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 1.951e-09 0.34
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 2.708e-09 0.43
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 2.739e-09 0.45
ISPT_STRPN uppS Isoprenyl transferase 3.78e-09 0.29
TIMP3_RAT Timp3 Metalloproteinase inhibitor 3 8.229e-09 0.31
Q25615_ONCVO Chitinase 1.695e-08 0.36
REV1_HUMAN REV1 DNA repair protein REV1 1.743e-08 0.32
MMP9_RAT Mmp9 Matrix metalloproteinase-9 2.604e-08 0.31
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 4.117e-08 0.32
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 4.168e-08 0.30
ROCK2_RAT Rock2 Rho-associated protein kinase 2 4.778e-08 0.32
CATK_HUMAN CTSK Cathepsin K 4.867e-08 0.33
LIPL_RAT Lpl Lipoprotein lipase 5.037e-08 0.30
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 6.198e-08 0.39
UBP47_HUMAN USP47 Ubiquitin carboxyl-terminal hydrolase 47 7.387e-08 0.29
GRM3_RAT Grm3 Metabotropic glutamate receptor 3 7.741e-08 0.31
LUCI_PHOPY Luciferin 4-monooxygenase 8.043e-08 0.36
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 1.158e-07 0.37
UROK_HUMAN PLAU Urokinase-type plasminogen activator 1.565e-07 0.34
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 1.621e-07 0.32
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 1.682e-07 0.38
DPP2_HUMAN DPP7 Dipeptidyl peptidase 2 2.504e-07 0.37
TPA_HUMAN PLAT Tissue-type plasminogen activator 2.615e-07 0.32
ADAM9_HUMAN ADAM9 Disintegrin and metalloproteinase domain-containing protein 9 2.82e-07 0.30
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 3.031e-07 0.40
PDE1B_HUMAN PDE1B Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B 5.215e-07 0.33
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 5.76e-07 0.33
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 5.944e-07 0.33
MTR1B_CHICK Melatonin receptor type 1B 6.148e-07 0.28
SENP7_HUMAN SENP7 Sentrin-specific protease 7 6.765e-07 0.38
EST1_RABIT Liver carboxylesterase 1 6.8e-07 0.32
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 1.034e-06 0.34
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 1.197e-06 0.38
ALBU_BOVIN ALB Serum albumin 1.309e-06 0.29
CATL1_HUMAN CTSL Cathepsin L1 1.451e-06 0.32
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 1.553e-06 0.31
PRIO_SHEEP PRNP Major prion protein 1.876e-06 0.30
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 2.409e-06 0.38
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 2.768e-06 0.40
C3SLB7_ECOLX glmU Bifunctional protein GlmU 3.313e-06 0.29
PDE9A_HUMAN PDE9A High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 3.623e-06 0.33
SCAF_HCMVA UL80 Capsid scaffolding protein 3.793e-06 0.31
TAAR1_RAT Taar1 Trace amine-associated receptor 1 7.064e-06 0.37
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 7.236e-06 0.31
OX1R_HUMAN HCRTR1 Orexin receptor type 1 7.251e-06 0.39
CATS_HUMAN CTSS Cathepsin S 9.172e-06 0.32
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 9.865e-06 0.33
FUCO_BOVIN FUCA1 Tissue alpha-L-fucosidase 9.9e-06 0.39

Tribromsalan

PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 0.005509 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.01251 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 0.01719 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.03037 1.00
LCK_HUMAN LCK Tyrosine-protein kinase Lck 0.05617 1.00
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 0.06949 1.00
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 0.8077 1.00
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 0.9498 1.00
Q25615_ONCVO Chitinase 3.28e-111 0.76
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 1.205e-49 0.34
TMPS4_HUMAN TMPRSS4 Transmembrane protease serine 4 3.333e-49 0.33
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 5.896e-46 0.31
Q6L5J4_HUMAN FPRL2 FML2_HUMAN 1.099e-43 0.33
KPYK_STAAR pyk Pyruvate kinase 1.617e-43 0.54
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 1.934e-39 0.35
MYO5A_CHICK MYO5A Unconventional myosin-Va 2.435e-37 0.30
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 1.21e-36 0.33
PRIO_SHEEP PRNP Major prion protein 2.402e-33 0.41
ACEA_CANAX ICL1 Isocitrate lyase 1.413e-30 0.31
PSBA_SPIOL psbA Photosystem II protein D1 3.38e-29 0.42
SORT_HUMAN SORT1 Sortilin 4.751e-28 0.41
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 3.002e-26 0.49
FA12_HUMAN F12 Coagulation factor XII 7.005e-26 0.37
PARG_HUMAN PARG Poly(ADP-ribose) glycohydrolase 1.744e-24 0.39
UROK_HUMAN PLAU Urokinase-type plasminogen activator 1.906e-20 0.56
TPA_HUMAN PLAT Tissue-type plasminogen activator 3.253e-19 0.53
ANDR_MOUSE Ar Androgen receptor 4.37e-18 0.39
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 7.167e-18 0.53
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 2.297e-17 0.40
BXE_CLOBO botE Botulinum neurotoxin type E 3.331e-17 0.43
MYG_HUMAN MB Myoglobin 5.295e-17 0.32
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 2.22e-16 0.34
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 2.109e-15 0.38
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 7.883e-15 0.28
FABH_STRP3 fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 7.883e-15 0.28
Q9HUN3_PSEAE dnaB Replicative DNA helicase 3.153e-14 0.31
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 4.174e-14 0.33
CH10_HUMAN HSPE1 10 kDa heat shock protein, mitochondrial 5.496e-14 0.48
CH60_HUMAN HSPD1 60 kDa heat shock protein, mitochondrial 5.496e-14 0.48
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 9.237e-14 0.32
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 1.097e-13 0.53
PSBA_MARPO psbA Photosystem II protein D1 3.841e-13 0.42
P89582_9HIV2 pol Integrase 5.641e-13 0.28
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 2.688e-12 0.29
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.733e-12 0.30
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 3.252e-12 0.30
C3SLB7_ECOLX glmU Bifunctional protein GlmU 4.057e-12 0.33
Q38C41_TRYB2 Phosphotransferase 7.403e-12 0.31
SENP7_HUMAN SENP7 Sentrin-specific protease 7 4.265e-11 0.42
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 5.823e-11 0.30
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.496e-10 0.30
WRN_HUMAN WRN Werner syndrome ATP-dependent helicase 6.171e-10 0.29
THB_RAT Thrb Thyroid hormone receptor beta 8.681e-10 0.29
PLEC_HUMAN PLEC Plectin 1.052e-09 0.35
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 1.413e-09 0.33
KCNQ2_RAT Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 1.674e-09 0.30
AOX_TRYBB AOX Alternative oxidase, mitochondrial 4.608e-09 0.28
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 4.765e-09 0.30
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 9.029e-09 0.31
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 1.23e-08 0.35
RXFP1_HUMAN RXFP1 Relaxin receptor 1 1.988e-08 0.35
DPOL_HHV6U U38 DNA polymerase catalytic subunit 2.572e-08 0.29
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 4.063e-08 0.31
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 4.574e-08 0.38
EST1_RABIT Liver carboxylesterase 1 7.744e-08 0.38
I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 7.955e-08 0.36
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 1.297e-07 0.31
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 1.589e-07 0.34
Q76353_9HIV1 Integrase 1.692e-07 0.45
SENP6_HUMAN SENP6 Sentrin-specific protease 6 1.742e-07 0.36
PANC_MYCTU panC Pantothenate synthetase 2.555e-07 0.36
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 3.701e-07 0.35
POLG_DEN2P Genome polyprotein 3.96e-07 0.30
PLMN_HUMAN PLG Plasminogen 8.164e-07 0.53
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 1.011e-06 0.51
SENP8_HUMAN SENP8 Sentrin-specific protease 8 1.344e-06 0.36
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 1.507e-06 0.30
NCOA1_HUMAN NCOA1 Nuclear receptor coactivator 1 1.842e-06 0.34
SMO_HUMAN SMO Smoothened homolog 1.992e-06 0.35
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 2.016e-06 0.35
LDLR_HUMAN LDLR Low-density lipoprotein receptor 2.049e-06 0.29
WNT3_HUMAN WNT3 Proto-oncogene Wnt-3 2.27e-06 0.35
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 2.417e-06 0.33
Q8IEK1_PLAF7 M1-family alanyl aminopeptidase 3.475e-06 0.31
TOP3_BACSU topB DNA topoisomerase 3 4.01e-06 0.29
VP16_HHV11 Tegument protein VP16 4.011e-06 0.34
STRP_STRP1 ska Streptokinase A 5.094e-06 0.42
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 5.16e-06 0.28
TOP1_HUMAN TOP1 DNA topoisomerase 1 6.025e-06 0.43
Q548M1_ECOLX groL 60 kDa chaperonin 6.619e-06 0.48
Q7BGE6_ECOLX groES 10 kDa chaperonin 6.619e-06 0.48
BLA2_BACCE blm Metallo-beta-lactamase type 2 7.112e-06 0.29
Q6FTL6_CANGA NCE103 Carbonic anhydrase 8.662e-06 0.41
PAR1_HUMAN F2R Proteinase-activated receptor 1 8.823e-06 0.35
PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 9.185e-06 0.33
TRYP_PIG Trypsin 9.456e-06 0.30
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 9.646e-06 0.38

Zoxazolamine

CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.07275 1.00
PLCB_HUMAN AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 1.686e-32 0.41
OX1R_MOUSE Hcrtr1 Orexin receptor type 1 8.657e-24 0.29
OX2R_MOUSE Hcrtr2 Orexin receptor type 2 8.657e-24 0.29
AHR_HUMAN AHR Aryl hydrocarbon receptor 7.302e-23 0.37
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 1.485e-21 0.44
5HT3A_MOUSE Htr3a 5-hydroxytryptamine receptor 3A 4.319e-21 0.45
AHR_MOUSE Ahr Aryl hydrocarbon receptor 3.153e-14 0.31
LOX5_MOUSE Alox5 Arachidonate 5-lipoxygenase 6.439e-14 0.50
TCMO_POPKI CYP73A16 Trans-cinnamate 4-monooxygenase 8.008e-11 0.33
ESR1_MOUSE Esr1 Estrogen receptor 1.441e-10 0.33
ESR2_MOUSE Esr2 Estrogen receptor beta 1.441e-10 0.33
PTGES_HUMAN PTGES Prostaglandin E synthase 1.247e-08 0.37
HRH4_HUMAN HRH4 Histamine H4 receptor 1.314e-08 0.35
SKN1_CAEEL skn-1 Protein skinhead-1 1.943e-08 0.35
CETP_HUMAN CETP Cholesteryl ester transfer protein 9.012e-08 0.37
HPSE_HUMAN HPSE Heparanase 1.941e-07 0.33
BCAT1_HUMAN BCAT1 Branched-chain-amino-acid aminotransferase, cytosolic 3.205e-07 0.29
Q548M1_ECOLX groL 60 kDa chaperonin 6.111e-07 0.29
Q7BGE6_ECOLX groES 10 kDa chaperonin 6.111e-07 0.29
SENP7_HUMAN SENP7 Sentrin-specific protease 7 8.324e-07 0.54
CAH3_HUMAN CA3 Carbonic anhydrase 3 3.659e-06 0.36

Crinecerfont

CRFR1_HUMAN CRHR1 Corticotropin-releasing factor receptor 1 0.6429 1.00
CXL10_HUMAN CXCL10 C-X-C motif chemokine 10 4.188e-21 0.33

Salicylanilide

RXFP1_HUMAN RXFP1 Relaxin receptor 1 5.369e-182 0.43
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 5.746e-152 0.50
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 7.701e-98 0.41
Q25615_ONCVO Chitinase 1.975e-95 0.45
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 1.065e-85 0.51
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 4.891e-78 0.47
STXA_SHIDY stxA Shiga toxin subunit A 4.196e-62 0.41
V2R_RAT Avpr2 Vasopressin V2 receptor 3.014e-58 0.45
RXFP2_HUMAN RXFP2 Relaxin receptor 2 5.139e-58 0.33
TMPS4_HUMAN TMPRSS4 Transmembrane protease serine 4 1.233e-56 0.36
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 1.466e-56 0.44
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 1.715e-56 0.44
C3SLB7_ECOLX glmU Bifunctional protein GlmU 4.035e-55 0.44
V1AR_RAT Avpr1a Vasopressin V1a receptor 9.059e-54 0.45
PRIO_SHEEP PRNP Major prion protein 6.005e-50 0.43
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 6.135e-50 0.66
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 3.897e-49 0.41
USP_DROME usp Protein ultraspiracle 3.986e-49 0.33
RCOR3_HUMAN RCOR3 REST corepressor 3 7.227e-49 0.39
BXE_CLOBO botE Botulinum neurotoxin type E 2.732e-48 0.61
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 8.864e-45 0.46
ECR_DROME EcR Ecdysone receptor 3.257e-40 0.33
BAP1_HUMAN BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1 7.545e-40 0.32
MGRA_STAAU mgrA HTH-type transcriptional regulator MgrA 1.157e-39 0.31
TCMO_HELTU CYP73A1 Trans-cinnamate 4-monooxygenase 1.381e-38 0.31
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.965e-38 0.33
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 2.244e-38 0.46
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 5.166e-38 0.35
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 1.739e-36 0.50
COX1_SHEEP MT-CO1 Cytochrome c oxidase subunit 1 1.775e-36 0.29
RAGE_RAT Ager Advanced glycosylation end product-specific receptor 3.875e-36 0.29
EPHB_MYCTO Epoxide hydrolase B 3.023e-33 0.54
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.453e-31 0.64
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 3.462e-31 0.44
V2R_HUMAN AVPR2 Vasopressin V2 receptor 1.878e-30 0.35
Q6FTL6_CANGA NCE103 Carbonic anhydrase 2.435e-30 0.43
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 2.893e-29 0.43
LUCI_AQULA Luciferin 4-monooxygenase 4.409e-29 0.33
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 1.126e-28 0.35
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 8.603e-28 0.41
NR1H4_HUMAN NR1H4 Bile acid receptor 1.431e-27 0.46
ECR_BOMMO EcR Ecdysone receptor 4.774e-27 0.33
MYOC_HUMAN MYOC Myocilin 5.245e-27 0.33
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 2.239e-26 0.47
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 3.021e-26 0.37
SUMO1_HUMAN SUMO1 Small ubiquitin-related modifier 1 5.827e-26 0.32
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 1.929e-25 0.42
BLAB_BACCE Metallo-beta-lactamase type 2 4.642e-25 0.28
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 2.215e-24 0.32
Q7K6A1_PLAF7 Histone deacetylase 3.022e-24 0.39
CAH9_HUMAN CA9 Carbonic anhydrase 9 5.096e-24 0.66
FABH_STAAM fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.847e-23 0.29
NEDD4_HUMAN NEDD4 E3 ubiquitin-protein ligase NEDD4 2.847e-23 0.29
EST1_RABIT Liver carboxylesterase 1 3.54e-23 0.34
CAH12_HUMAN CA12 Carbonic anhydrase 12 3.577e-23 0.47
HMGB1_HUMAN HMGB1 High mobility group protein B1 5.518e-23 0.28
CAN_CANAL NCE103 Carbonic anhydrase 9.067e-23 0.43
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.002e-22 0.54
LIPL_RAT Lpl Lipoprotein lipase 2.345e-22 0.30
UROK_HUMAN PLAU Urokinase-type plasminogen activator 3.87e-22 0.64
TPA_HUMAN PLAT Tissue-type plasminogen activator 1.073e-21 0.64
EGFR_MOUSE Egfr Epidermal growth factor receptor 1.287e-21 0.33
CAH1_HUMAN CA1 Carbonic anhydrase 1 3.115e-21 0.66
SENP7_HUMAN SENP7 Sentrin-specific protease 7 3.463e-21 0.47
SORT_HUMAN SORT1 Sortilin 3.842e-21 0.38
ANDR_MOUSE Ar Androgen receptor 4.137e-21 0.64
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 1.233e-20 0.46
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 2.425e-20 0.41
A5H660_SCHMA HDAC8 Histone deacetylase 8 2.792e-20 0.42
CFTR_HUMAN CFTR Cystic fibrosis transmembrane conductance regulator 3.439e-20 0.47
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 3.895e-20 0.35
CAH2_HUMAN CA2 Carbonic anhydrase 2 6.154e-20 0.47
SMO_HUMAN SMO Smoothened homolog 9.22e-20 0.55
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 1.24e-19 0.38
LUCI_PHOPY Luciferin 4-monooxygenase 1.48e-19 0.44
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 5.485e-19 0.43
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 6.741e-19 0.30
AHK3_ARATH AHK3 Histidine kinase 3 9.915e-19 0.36
FA12_HUMAN F12 Coagulation factor XII 1.231e-18 0.39
MYG_HUMAN MB Myoglobin 1.594e-18 0.35
PARG_HUMAN PARG Poly(ADP-ribose) glycohydrolase 2.375e-18 0.29
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 2.692e-18 0.36
AOX_TRYBB AOX Alternative oxidase, mitochondrial 3.553e-18 0.59
ANO1_HUMAN ANO1 Anoctamin-1 4.409e-18 0.33
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 5.962e-18 0.30
LYAM1_HUMAN SELL L-selectin 9.997e-18 0.33
HDAC8_HUMAN HDAC8 Histone deacetylase 8 4.743e-17 0.52
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 5.151e-17 0.33
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 1.11e-16 0.49
DOPO_HUMAN DBH Dopamine beta-hydroxylase 1.11e-16 0.36
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 1.11e-16 0.54
G2YM83_BOTF4 Cytochrome b-c1 complex subunit Rieske, mitochondrial 1.11e-16 0.31
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 1.11e-16 0.36
EST2_HUMAN CES2 Cocaine esterase 3.331e-16 0.33
TYRO_MOUSE Tyr Tyrosinase 4.441e-16 0.40
BCAT2_HUMAN BCAT2 Branched-chain-amino-acid aminotransferase, mitochondrial 6.661e-16 0.41
UREA_CANEN Urease 1.332e-15 0.36
PA_I000X PA Polymerase acidic protein 1.665e-15 0.29
RCOR1_HUMAN RCOR1 REST corepressor 1 1.998e-15 0.38
HIS1_MYCTU hisG ATP phosphoribosyltransferase 3.442e-15 0.33
FABH_STRP3 fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 4.441e-15 0.29
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 4.885e-15 0.43
APOB_HUMAN APOB Apolipoprotein B-100 7.55e-15 0.32
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 7.883e-15 0.53
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 7.994e-15 0.34
AURKA_HUMAN AURKA Aurora kinase A 1.121e-14 0.45
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 1.188e-14 0.46
AHK4_ARATH AHK4 Histidine kinase 4 1.532e-14 0.36
VE1_HPV11 E1 Replication protein E1 1.765e-14 0.38
NOX1_HUMAN NOX1 NADPH oxidase 1 1.776e-14 0.40
STRP_STRP1 ska Streptokinase A 2.254e-14 0.46
E3UJZ5_SPOLI Ecdysone receptor 2.709e-14 0.30
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 4.041e-14 0.44
HDAC1_HUMAN HDAC1 Histone deacetylase 1 5.362e-14 0.42
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 6.506e-14 0.38
HDAC2_HUMAN HDAC2 Histone deacetylase 2 7.172e-14 0.52
POLG_CXB3N Genome polyprotein 8.393e-14 0.33
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 2.56e-13 0.39
AGTR1_RABIT AGTR1 Type-1 angiotensin II receptor 2.85e-13 0.33
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 3.242e-13 0.46
PLEC_HUMAN PLEC Plectin 3.697e-13 0.39
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 3.748e-13 0.34
HDAC6_HUMAN HDAC6 Histone deacetylase 6 5.305e-13 0.52
LYOX_HUMAN LOX Protein-lysine 6-oxidase 5.589e-13 0.35
TAT_HV112 tat Protein Tat 8.415e-13 0.30
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 9.449e-13 0.64
PAR1_HUMAN F2R Proteinase-activated receptor 1 1.011e-12 0.41
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.222e-12 0.33
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 1.286e-12 0.42
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 1.311e-12 0.38
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 1.372e-12 0.36
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 1.452e-12 0.38
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 1.452e-12 0.38
Q7ZJM1_9HIV1 pol Integrase 1.521e-12 0.50
ARBK2_HUMAN GRK3 Beta-adrenergic receptor kinase 2 2.359e-12 0.30
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.439e-12 0.48
LYAM3_HUMAN SELP P-selectin 2.455e-12 0.33
EST1_HUMAN CES1 Liver carboxylesterase 1 3.06e-12 0.33
ANO2_HUMAN ANO2 Anoctamin-2 7.204e-12 0.32
KLK2_HUMAN KLK2 Kallikrein-2 7.334e-12 0.29
CAH4_BOVIN CA4 Carbonic anhydrase 4 8.433e-12 0.44
O68720_YERPE yopH Targeted effector protein 9.622e-12 0.31
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 9.784e-12 0.40
HDAC7_HUMAN HDAC7 Histone deacetylase 7 1.159e-11 0.39
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 1.257e-11 0.37
ATM_HUMAN ATM Serine-protein kinase ATM 1.292e-11 0.38
Q76353_9HIV1 Integrase 1.331e-11 0.52
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.625e-11 0.32
TRYP_PIG Trypsin 1.843e-11 0.41
SENP6_HUMAN SENP6 Sentrin-specific protease 6 1.959e-11 0.47
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 2.335e-11 0.33
PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 2.624e-11 0.45
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 2.775e-11 0.38
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 3.16e-11 0.33
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 3.441e-11 0.38
Q9NBA7_PLAFA Cysteine protease falcipain-3 3.542e-11 0.30
RECA_MYCTU recA Protein RecA 3.601e-11 0.50
PSBA_SPIOL psbA Photosystem II protein D1 5.328e-11 0.45
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 5.57e-11 0.46
NCOA1_HUMAN NCOA1 Nuclear receptor coactivator 1 6.76e-11 0.44
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 8.11e-11 0.46
KLK8_HUMAN KLK8 Kallikrein-8 8.581e-11 0.29
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 8.808e-11 0.39
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 8.878e-11 0.29
PA_I34A1 PA Polymerase acidic protein 9.293e-11 0.32
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 1.061e-10 0.36
H9B8T9_CAPHI CTSB Cathepsin B 1.325e-10 0.36
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 1.49e-10 0.41
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 1.776e-10 0.39
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 2.628e-10 0.35
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 2.824e-10 0.48
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 3.131e-10 0.46
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 3.484e-10 0.30
O31272_9GAMM imiS Beta-lactamase 3.547e-10 0.32
DNAB_MYCTU dnaB Replicative DNA helicase 3.958e-10 0.50
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 4.052e-10 0.41
TOP1_HUMAN TOP1 DNA topoisomerase 1 4.611e-10 0.44
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 5.303e-10 0.44
KLK4_HUMAN KLK4 Kallikrein-4 5.982e-10 0.29
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 6.401e-10 0.35
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 7.529e-10 0.41
MATK_HUMAN MATK Megakaryocyte-associated tyrosine-protein kinase 9.904e-10 0.39
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 1.237e-09 0.34
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 1.337e-09 0.39
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 1.35e-09 0.39
MITF_HUMAN MITF Microphthalmia-associated transcription factor 1.423e-09 0.36
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 1.439e-09 0.40
HSF1_MOUSE Hsf1 Heat shock factor protein 1 1.595e-09 0.42
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 1.882e-09 0.42
CXCR2_HUMAN CXCR2 C-X-C chemokine receptor type 2 2.303e-09 0.37
O77078_PLAFA fabH Beta-ketoacyl-acyl carrier protein synthase III 2.663e-09 0.31
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 2.75e-09 0.33
PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 3.049e-09 0.39
SHH_MOUSE Shh Sonic hedgehog protein 3.122e-09 0.37
DUS3_HUMAN DUSP3 Dual specificity protein phosphatase 3 3.178e-09 0.45
Q8IEK1_PLAF7 M1-family alanyl aminopeptidase 3.547e-09 0.33
PANC_MYCTU panC Pantothenate synthetase 4.119e-09 0.37
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 5.085e-09 0.41
KPYK_STAAR pyk Pyruvate kinase 5.873e-09 0.35
AURKB_HUMAN AURKB Aurora kinase B 5.982e-09 0.43
CAH7_HUMAN CA7 Carbonic anhydrase 7 6.352e-09 0.35
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 6.567e-09 0.33
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 7.726e-09 0.41
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 8.011e-09 0.31
PRKDC_HUMAN PRKDC DNA-dependent protein kinase catalytic subunit 8.93e-09 0.38
BRSK1_HUMAN BRSK1 Serine/threonine-protein kinase BRSK1 9.34e-09 0.39
KCC2G_HUMAN CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 1.059e-08 0.39
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 1.249e-08 0.38
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 1.617e-08 0.36
HDA11_HUMAN HDAC11 Histone deacetylase 11 1.621e-08 0.39
Q56950_YERPE ybtE Salicyl-AMP ligase YbtE 1.702e-08 0.29
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 1.727e-08 0.31
SCRB1_MOUSE Scarb1 Scavenger receptor class B member 1 1.751e-08 0.47
FA10_HUMAN F10 Coagulation factor X 1.812e-08 0.41
KLK6_HUMAN KLK6 Kallikrein-6 2.572e-08 0.29
LYAM2_HUMAN SELE E-selectin 3.03e-08 0.33
HDAC9_HUMAN HDAC9 Histone deacetylase 9 3.069e-08 0.39
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 3.075e-08 0.34
KLK1_HUMAN KLK1 Kallikrein-1 3.105e-08 0.41
MARK3_HUMAN MARK3 MAP/microtubule affinity-regulating kinase 3 3.129e-08 0.39
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 3.182e-08 0.50
SCYD_MAGO7 SDH1 Scytalone dehydratase 3.193e-08 0.47
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 3.279e-08 0.32
I23O1_MOUSE Ido1 Indoleamine 2,3-dioxygenase 1 3.786e-08 0.32
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 3.839e-08 0.36
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 4.078e-08 0.38
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 4.334e-08 0.39
PYRD_RAT Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 5.231e-08 0.39
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 5.278e-08 0.41
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 5.917e-08 0.34
KCC2B_HUMAN CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta 7.218e-08 0.39
WNT3A_MOUSE Wnt3a Protein Wnt-3a 7.986e-08 0.31
CAH14_HUMAN CA14 Carbonic anhydrase 14 8.519e-08 0.35
DDIT3_HUMAN DDIT3 DNA damage-inducible transcript 3 protein 9.028e-08 0.32
CAH3_BOVIN CA3 Carbonic anhydrase 3 9.381e-08 0.33
INSR_MOUSE Insr Insulin receptor 1.031e-07 0.29
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 1.266e-07 0.28
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 1.511e-07 0.29
AGP1_YEAST AGP1 General amino acid permease AGP1 1.526e-07 0.38
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 1.591e-07 0.33
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 1.596e-07 0.39
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 1.642e-07 0.32
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 1.649e-07 0.41
KLF5_HUMAN KLF5 Krueppel-like factor 5 1.848e-07 0.34
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 1.939e-07 0.30
HDAC4_HUMAN HDAC4 Histone deacetylase 4 2.031e-07 0.41
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 2.208e-07 0.34
POLG_DEN2P Genome polyprotein 2.358e-07 0.31
CASP3_HUMAN CASP3 Caspase-3 2.617e-07 0.36
PLMN_HUMAN PLG Plasminogen 2.852e-07 0.42
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 3.048e-07 0.41
MMP2_HUMAN MMP2 72 kDa type IV collagenase 3.118e-07 0.41
GATA4_MOUSE Gata4 Transcription factor GATA-4 3.205e-07 0.29
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 3.205e-07 0.29
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 3.217e-07 0.38
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 3.334e-07 0.33
CYNT_HELPY cynT Carbonic anhydrase 3.349e-07 0.31
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 3.608e-07 0.46
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 3.805e-07 0.33
SENP8_HUMAN SENP8 Sentrin-specific protease 8 4.15e-07 0.47
MMP1_HUMAN MMP1 Interstitial collagenase 4.163e-07 0.41
ACRO_HUMAN ACR Acrosin 4.219e-07 0.31
Q8MTZ4_9TRYP PPase1 Vacuolar-type proton translocating pyrophosphatase 1 4.707e-07 0.30
EGFR_HUMAN EGFR Epidermal growth factor receptor 5.941e-07 0.50
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 6.893e-07 0.32
CAH4_HUMAN CA4 Carbonic anhydrase 4 7.388e-07 0.33
PERM_HUMAN MPO Myeloperoxidase 7.78e-07 0.59
TTHY_HUMAN TTR Transthyretin 8.48e-07 0.33
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 8.508e-07 0.40
Q8ST54_TRYCR HK Phosphotransferase 8.676e-07 0.30
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 9.182e-07 0.31
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 9.396e-07 0.29
KC1G2_HUMAN CSNK1G2 Casein kinase I isoform gamma-2 9.85e-07 0.39
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 9.933e-07 0.39
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 1.092e-06 0.39
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 1.139e-06 0.32
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 1.161e-06 0.39
5NTD_RAT Nt5e 5'-nucleotidase 1.162e-06 0.33
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 1.235e-06 0.39
SMO_MOUSE Smo Smoothened homolog 1.255e-06 0.40
MAPK3_HUMAN MAPKAPK3 MAP kinase-activated protein kinase 3 1.288e-06 0.28
CBPA1_BOVIN CPA1 Carboxypeptidase A1 1.314e-06 0.36
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 1.369e-06 0.29
Q8IL32_PLAF7 Heat shock protein 90, putative 1.422e-06 0.39
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 1.546e-06 0.43
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 1.587e-06 0.29
DYRK4_HUMAN DYRK4 Dual specificity tyrosine-phosphorylation-regulated kinase 4 1.622e-06 0.29
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 1.624e-06 0.31
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.627e-06 0.39
PRIO_MESAU PRNP Major prion protein 1.657e-06 0.30
S12A5_HUMAN SLC12A5 Solute carrier family 12 member 5 1.665e-06 0.38
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 1.72e-06 0.30
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 1.77e-06 0.32
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 1.823e-06 0.30
CDK19_HUMAN CDK19 Cyclin-dependent kinase 19 1.853e-06 0.30
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 2.11e-06 0.32
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 2.112e-06 0.41
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 2.145e-06 0.39
HDAC5_HUMAN HDAC5 Histone deacetylase 5 2.222e-06 0.39
NOX4_HUMAN NOX4 NADPH oxidase 4 2.41e-06 0.38
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 2.458e-06 0.40
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 2.567e-06 0.39
AAPK1_HUMAN PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 2.605e-06 0.39
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 2.709e-06 0.33
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 2.726e-06 0.30
Q9V396_DROME CAH1 Carbonic anhydrase 1 2.768e-06 0.40
Q9VTU8_DROME CAH2 Carbonic anhydrase 2, isoform A 2.768e-06 0.40
MINK1_HUMAN MINK1 Misshapen-like kinase 1 3.01e-06 0.39
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 3.124e-06 0.31
LDLR_HUMAN LDLR Low-density lipoprotein receptor 3.213e-06 0.28
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 3.22e-06 0.33
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 3.436e-06 0.47
EGLN1_HUMAN EGLN1 Egl nine homolog 1 3.598e-06 0.49
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 3.627e-06 0.44
PLK4_HUMAN PLK4 Serine/threonine-protein kinase PLK4 3.654e-06 0.39
Q9XYC7_PLAFA HDAC1 Histone deacetylase 3.958e-06 0.39
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 3.961e-06 0.39
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 4.174e-06 0.47
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 4.239e-06 0.34
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 4.646e-06 0.39
MIF_HUMAN MIF Macrophage migration inhibitory factor 4.956e-06 0.36
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 5.028e-06 0.42
NEK4_HUMAN NEK4 Serine/threonine-protein kinase Nek4 5.135e-06 0.39
BLK_HUMAN BLK Tyrosine-protein kinase Blk 5.339e-06 0.39
PAG_BACAN pagA Protective antigen 5.346e-06 0.36
Q8MWR1_SPOFR USP Ultraspiracle protein 5.455e-06 0.30
Q8MWR2_SPOFR EcR Ecdysteroid receptor 5.455e-06 0.30
O69002_PSEAI pigA Biliverdin-producing heme oxygenase 5.777e-06 0.32
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 6.011e-06 0.43
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 6.3e-06 0.39
BRPF1_HUMAN BRPF1 Peregrin 6.607e-06 0.34
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 6.636e-06 0.32
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 6.71e-06 0.38
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 6.816e-06 0.34
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 6.946e-06 0.39
CAH3_HUMAN CA3 Carbonic anhydrase 3 7.089e-06 0.35
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 7.252e-06 0.39
GLI1_MOUSE Gli1 Zinc finger protein GLI1 8.051e-06 0.41
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 8.09e-06 0.28
BLA2_BACCE blm Metallo-beta-lactamase type 2 8.558e-06 0.28
DYRK3_HUMAN DYRK3 Dual specificity tyrosine-phosphorylation-regulated kinase 3 9.415e-06 0.39
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 9.521e-06 0.34
PDGFB_HUMAN PDGFB Platelet-derived growth factor subunit B 9.582e-06 0.30
MK13_HUMAN MAPK13 Mitogen-activated protein kinase 13 9.922e-06 0.32

Benzoylpas

KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.763e-172 0.53
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.181e-141 0.41
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 5.996e-125 0.42
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 2.75e-104 0.44
PRIO_SHEEP PRNP Major prion protein 2.269e-98 0.53
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.293e-95 0.50
RXFP1_HUMAN RXFP1 Relaxin receptor 1 1.318e-94 0.44
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 2.365e-87 0.49
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.126e-74 0.46
Q25615_ONCVO Chitinase 2.627e-74 0.42
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 4.901e-74 0.38
BXE_CLOBO botE Botulinum neurotoxin type E 7.091e-71 0.46
FABH_STRP3 fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.951e-65 0.35
A5H660_SCHMA HDAC8 Histone deacetylase 8 5.851e-59 0.53
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 2.967e-58 0.33
Q38C41_TRYB2 Phosphotransferase 6.844e-58 0.40
SORT_HUMAN SORT1 Sortilin 1.386e-56 0.41
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 5.048e-55 0.45
FABH_STAAM fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.113e-53 0.35
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 2.26e-53 0.34
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 3.009e-52 0.41
USP_DROME usp Protein ultraspiracle 3.173e-50 0.33
SENP1_HUMAN SENP1 Sentrin-specific protease 1 6.08e-50 0.39
ENL_HUMAN MLLT1 Protein ENL 2.364e-49 0.32
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 1.47e-47 0.34
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 2.378e-47 0.35
LUCI_AQULA Luciferin 4-monooxygenase 6.479e-47 0.40
CBPC2_HUMAN AGBL2 Cytosolic carboxypeptidase 2 7.497e-47 0.37
TMPS4_HUMAN TMPRSS4 Transmembrane protease serine 4 2.944e-45 0.28
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 3.035e-45 0.38
V2R_RAT Avpr2 Vasopressin V2 receptor 8.18e-45 0.41
NR1H4_HUMAN NR1H4 Bile acid receptor 5.277e-44 0.46
COX1_SHEEP MT-CO1 Cytochrome c oxidase subunit 1 1.651e-43 0.35
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 1.267e-42 0.61
PHHY_PSEFL pobA p-hydroxybenzoate hydroxylase 5.166e-42 0.33
FABH_HAEIN fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.89e-41 0.33
ECR_DROME EcR Ecdysone receptor 4.124e-41 0.33
MGRA_STAAU mgrA HTH-type transcriptional regulator MgrA 5.512e-41 0.33
SHH_MOUSE Shh Sonic hedgehog protein 5.537e-41 0.46
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 6.433e-40 0.49
KCNB2_HUMAN KCNB2 Potassium voltage-gated channel subfamily B member 2 9.952e-40 0.31
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 1.409e-39 0.43
V1AR_RAT Avpr1a Vasopressin V1a receptor 1.434e-37 0.41
GUAA_MOUSE Gmps GMP synthase [glutamine-hydrolyzing] 1.917e-37 0.30
SENP7_HUMAN SENP7 Sentrin-specific protease 7 7.006e-37 0.43
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 9.201e-37 0.48
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 1.022e-36 0.32
SSU72_HUMAN SSU72 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 1.195e-36 0.29
SENP2_HUMAN SENP2 Sentrin-specific protease 2 1.948e-36 0.29
RXFP2_HUMAN RXFP2 Relaxin receptor 2 3.079e-36 0.30
TCMO_HELTU CYP73A1 Trans-cinnamate 4-monooxygenase 3.875e-36 0.29
TRPV1_CAVPO Trpv1 Transient receptor potential cation channel subfamily V member 1 7.62e-36 0.28
BAP1_HUMAN BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1 1.377e-35 0.28
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 1.898e-35 0.32
HDAC1_HUMAN HDAC1 Histone deacetylase 1 2.601e-34 0.50
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 3.449e-34 0.46
LYAM1_HUMAN SELL L-selectin 7.782e-34 0.39
ECR_BOMMO EcR Ecdysone receptor 2.283e-33 0.33
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 4.311e-33 0.62
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 1.113e-32 0.33
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 1.26e-32 0.48
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 7.11e-32 0.32
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 1.29e-31 0.36
ANDR_MOUSE Ar Androgen receptor 8.463e-31 0.50
UROK_HUMAN PLAU Urokinase-type plasminogen activator 3.51e-30 0.49
EST1_RABIT Liver carboxylesterase 1 9.519e-30 0.35
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 4.325e-29 0.35
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 7.095e-29 0.45
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.442e-28 0.36
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.53e-28 0.59
UREA_CANEN Urease 1.634e-28 0.42
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 3.94e-28 0.34
PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 4.049e-28 0.41
LUCI_PHOPY Luciferin 4-monooxygenase 7.823e-28 0.47
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.79e-27 0.40
FSHR_RAT Fshr Follicle-stimulating hormone receptor 5.245e-27 0.33
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 6.709e-27 0.52
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 1.288e-26 0.34
SMO_HUMAN SMO Smoothened homolog 1.743e-26 0.53
TPA_HUMAN PLAT Tissue-type plasminogen activator 3.425e-26 0.42
STXA_SHIDY stxA Shiga toxin subunit A 1.333e-25 0.36
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 3.343e-25 0.33
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 3.796e-25 0.36
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 8.803e-25 0.39
FSHR_HUMAN FSHR Follicle-stimulating hormone receptor 1.414e-24 0.33
LYOX_HUMAN LOX Protein-lysine 6-oxidase 6.858e-24 0.35
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 9.014e-24 0.44
PRKDC_MOUSE Prkdc DNA-dependent protein kinase catalytic subunit 9.719e-24 0.29
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 1.14e-23 0.48
PTN14_HUMAN PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1.348e-23 0.29
PTN3_HUMAN PTPN3 Tyrosine-protein phosphatase non-receptor type 3 1.348e-23 0.29
PTPRM_HUMAN PTPRM Receptor-type tyrosine-protein phosphatase mu 1.348e-23 0.29
SENP6_HUMAN SENP6 Sentrin-specific protease 6 2.098e-23 0.43
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 3.575e-23 0.40
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 6.975e-23 0.42
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 9.776e-23 0.48
Q2PCB5_DICLA ca Carbonic anhydrase 1.383e-22 0.32
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 2.039e-22 0.36
E3UJZ5_SPOLI Ecdysone receptor 2.408e-22 0.33
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 2.423e-22 0.35
POLG_DEN2P Genome polyprotein 3.649e-22 0.38
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 5.371e-22 0.44
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 8.038e-22 0.35
EPHB_MYCTO Epoxide hydrolase B 1.778e-21 0.34
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 2.298e-21 0.31
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 2.563e-21 0.40
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 3.008e-21 0.35
AOX_TRYBB AOX Alternative oxidase, mitochondrial 4.366e-21 0.35
LYAM3_HUMAN SELP P-selectin 6.554e-21 0.39
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 6.809e-21 0.50
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 1.017e-20 0.41
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 1.151e-20 0.30
EGFR_MOUSE Egfr Epidermal growth factor receptor 1.444e-20 0.31
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 2.67e-20 0.33
KAPCA_BOVIN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 3.089e-20 0.31
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 6.369e-20 0.41
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 7.726e-20 0.42
PYGL_RAT Pygl Glycogen phosphorylase, liver form 1.225e-19 0.31
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 1.655e-19 0.45
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 4.843e-19 0.34
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 5.654e-19 0.35
PARG_HUMAN PARG Poly(ADP-ribose) glycohydrolase 6.741e-19 0.30
RCOR1_HUMAN RCOR1 REST corepressor 1 7.608e-19 0.44
LDLR_HUMAN LDLR Low-density lipoprotein receptor 9.182e-19 0.36
DUS10_HUMAN DUSP10 Dual specificity protein phosphatase 10 2.749e-18 0.29
DUS23_HUMAN DUSP23 Dual specificity protein phosphatase 23 2.749e-18 0.29
APOB_HUMAN APOB Apolipoprotein B-100 3.255e-18 0.35
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 3.368e-18 0.41
CAH12_HUMAN CA12 Carbonic anhydrase 12 3.47e-18 0.51
CAH7_HUMAN CA7 Carbonic anhydrase 7 3.494e-18 0.38
AUKBA_XENLA aurkb-a Aurora kinase B-A 3.72e-18 0.29
C3SLN3_ECOLX gyrB DNA gyrase subunit B 3.997e-18 0.31
TNR16_HUMAN NGFR Tumor necrosis factor receptor superfamily member 16 4.666e-18 0.40
TAAR1_RAT Taar1 Trace amine-associated receptor 1 5.901e-18 0.40
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 6.023e-18 0.39
O70424_RAT Neuropeptide Y-Y2 receptor 6.785e-18 0.28
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 9.056e-18 0.28
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 1.001e-17 0.40
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 1.389e-17 0.37
HDAC2_HUMAN HDAC2 Histone deacetylase 2 1.61e-17 0.47
MBTD1_HUMAN MBTD1 MBT domain-containing protein 1 1.805e-17 0.32
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 3.27e-17 0.48
CFTR_HUMAN CFTR Cystic fibrosis transmembrane conductance regulator 3.509e-17 0.36
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.11e-16 0.51
Q76353_9HIV1 Integrase 1.11e-16 0.44
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 1.11e-16 0.36
TRAP_STAAM traP Signal transduction protein TRAP 1.11e-16 0.29
EST2_HUMAN CES2 Cocaine esterase 2.22e-16 0.34
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 2.22e-16 0.44
POLG_CXB3N Genome polyprotein 2.22e-16 0.41
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 3.331e-16 0.38
PA_I000X PA Polymerase acidic protein 3.331e-16 0.31
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 3.331e-16 0.37
STRP_STRP1 ska Streptokinase A 4.441e-16 0.42
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 8.882e-16 0.30
AOFB_RAT Maob Amine oxidase [flavin-containing] B 1.887e-15 0.46
CAH9_HUMAN CA9 Carbonic anhydrase 9 1.887e-15 0.51
SENP8_HUMAN SENP8 Sentrin-specific protease 8 1.887e-15 0.40
GPR35_HUMAN GPR35 G-protein coupled receptor 35 1.998e-15 0.41
HDAC8_HUMAN HDAC8 Histone deacetylase 8 2.22e-15 0.53
Q9AQH7_STAAU dnaC Replicative DNA helicase 2.22e-15 0.38
EST1_HUMAN CES1 Liver carboxylesterase 1 2.331e-15 0.37
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 2.554e-15 0.44
MYG_HUMAN MB Myoglobin 2.887e-15 0.29
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 3.997e-15 0.43
KCNQ2_RAT Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 4.441e-15 0.35
UT2_RAT Slc14a2 Urea transporter 2 4.441e-15 0.29
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 5.218e-15 0.32
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 5.995e-15 0.37
LMBL3_HUMAN L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 6.328e-15 0.39
CAH4_HUMAN CA4 Carbonic anhydrase 4 6.55e-15 0.38
V2R_HUMAN AVPR2 Vasopressin V2 receptor 6.883e-15 0.38
SCAF_HCMVA UL80 Capsid scaffolding protein 1.232e-14 0.36
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 1.354e-14 0.29
MITF_HUMAN MITF Microphthalmia-associated transcription factor 1.443e-14 0.39
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 1.921e-14 0.32
Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 1.954e-14 0.34
LMBL1_HUMAN L3MBTL1 Lethal(3)malignant brain tumor-like protein 1 2.554e-14 0.32
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 2.909e-14 0.39
CAH2_HUMAN CA2 Carbonic anhydrase 2 3.741e-14 0.51
PTN7_HUMAN PTPN7 Tyrosine-protein phosphatase non-receptor type 7 4.152e-14 0.38
FUT7_HUMAN FUT7 Alpha-(1,3)-fucosyltransferase 7 5.473e-14 0.31
ARBK2_HUMAN GRK3 Beta-adrenergic receptor kinase 2 6.517e-14 0.35
GATA4_MOUSE Gata4 Transcription factor GATA-4 8.016e-14 0.31
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 8.016e-14 0.31
AURKA_HUMAN AURKA Aurora kinase A 8.127e-14 0.41
TP53B_HUMAN TP53BP1 TP53-binding protein 1 8.293e-14 0.30
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 1.176e-13 0.49
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 1.467e-13 0.51
CASP3_HUMAN CASP3 Caspase-3 1.842e-13 0.48
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 2.185e-13 0.55
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 2.253e-13 0.38
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 2.731e-13 0.34
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 3.029e-13 0.35
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 3.386e-13 0.39
PAR14_HUMAN PARP14 Protein mono-ADP-ribosyltransferase PARP14 3.739e-13 0.33
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 4.613e-13 0.38
P89582_9HIV2 pol Integrase 5.641e-13 0.28
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 6.09e-13 0.30
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 6.255e-13 0.37
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 6.477e-13 0.42
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 7.124e-13 0.44
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 8.836e-13 0.45
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 9.19e-13 0.44
KLF5_HUMAN KLF5 Krueppel-like factor 5 1.107e-12 0.35
IL5_MOUSE Il5 Interleukin-5 1.261e-12 0.36
KLK7_HUMAN KLK7 Kallikrein-7 1.48e-12 0.40
RARA_HUMAN RARA Retinoic acid receptor alpha 1.959e-12 0.41
Q7ZJM1_9HIV1 pol Integrase 2.242e-12 0.47
TRPV4_RAT Trpv4 Transient receptor potential cation channel subfamily V member 4 2.667e-12 0.39
KPCL_HUMAN PRKCH Protein kinase C eta type 3.683e-12 0.32
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 3.983e-12 0.38
DNLI1_HUMAN LIG1 DNA ligase 1 4.114e-12 0.30
TOP1_HUMAN TOP1 DNA topoisomerase 1 4.152e-12 0.47
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 4.737e-12 0.30
HSF1_MOUSE Hsf1 Heat shock factor protein 1 5.668e-12 0.38
CTNB1_HUMAN CTNNB1 Catenin beta-1 6.159e-12 0.30
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 8.252e-12 0.34
PDK1_HUMAN PDK1 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 8.753e-12 0.50
ITA2_HUMAN ITGA2 Integrin alpha-2 9.954e-12 0.33
WNT3_HUMAN WNT3 Proto-oncogene Wnt-3 1.137e-11 0.31
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 1.349e-11 0.37
CYNT_HELPY cynT Carbonic anhydrase 1.401e-11 0.38
Q9NBA7_PLAFA Cysteine protease falcipain-3 1.462e-11 0.31
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.545e-11 0.48
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 1.824e-11 0.46
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 2.083e-11 0.31
PLMN_HUMAN PLG Plasminogen 2.144e-11 0.49
RNH1_HUMAN RNASEH1 Ribonuclease H1 2.335e-11 0.33
PLEC_HUMAN PLEC Plectin 2.601e-11 0.48
HDAC6_HUMAN HDAC6 Histone deacetylase 6 2.643e-11 0.53
BCAT2_HUMAN BCAT2 Branched-chain-amino-acid aminotransferase, mitochondrial 2.776e-11 0.43
O68720_YERPE yopH Targeted effector protein 2.976e-11 0.30
Q6FTL6_CANGA NCE103 Carbonic anhydrase 3.453e-11 0.33
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 5.539e-11 0.43
KPCG_HUMAN PRKCG Protein kinase C gamma type 6.046e-11 0.32
TNFA_HUMAN TNF Tumor necrosis factor 6.287e-11 0.39
DUS3_HUMAN DUSP3 Dual specificity protein phosphatase 3 6.515e-11 0.41
KPCE_HUMAN PRKCE Protein kinase C epsilon type 6.665e-11 0.32
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 7.717e-11 0.37
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 8.133e-11 0.31
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 8.87e-11 0.49
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 8.878e-11 0.29
TF_HUMAN F3 Tissue factor 9.759e-11 0.34
TPOR_HUMAN MPL Thrombopoietin receptor 9.826e-11 0.32
CAH2_BOVIN CA2 Carbonic anhydrase 2 1.054e-10 0.32
UT1_RAT Slc14a1 Urea transporter 1 1.105e-10 0.29
ANM3_HUMAN PRMT3 Protein arginine N-methyltransferase 3 1.135e-10 0.34
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 1.189e-10 0.44
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 1.257e-10 0.33
TRYP_PIG Trypsin 1.281e-10 0.38
PTN5_HUMAN PTPN5 Tyrosine-protein phosphatase non-receptor type 5 1.42e-10 0.33
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.606e-10 0.46
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.607e-10 0.39
DNAB_MYCTU dnaB Replicative DNA helicase 1.619e-10 0.39
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 2.048e-10 0.53
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 2.049e-10 0.30
ITB3_HUMAN ITGB3 Integrin beta-3 2.286e-10 0.37
PERM_HUMAN MPO Myeloperoxidase 2.4e-10 0.39
LYAM2_HUMAN SELE E-selectin 2.462e-10 0.39
CAH3_HUMAN CA3 Carbonic anhydrase 3 2.621e-10 0.31
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 3.107e-10 0.32
RECA_MYCTU recA Protein RecA 3.277e-10 0.39
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 3.876e-10 0.40
LCK_HUMAN LCK Tyrosine-protein kinase Lck 4.494e-10 0.38
VE1_HPV11 E1 Replication protein E1 4.825e-10 0.35
Q548M1_ECOLX groL 60 kDa chaperonin 5.383e-10 0.29
Q7BGE6_ECOLX groES 10 kDa chaperonin 5.383e-10 0.29
UBCP1_HUMAN UBLCP1 Ubiquitin-like domain-containing CTD phosphatase 1 5.575e-10 0.29
Q8IEK1_PLAF7 M1-family alanyl aminopeptidase 6.734e-10 0.37
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 7.319e-10 0.40
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 7.667e-10 0.38
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 8.523e-10 0.29
HSP12_CAEEL hsp-16.2 Heat shock protein Hsp-16.2 1.087e-09 0.28
ST17A_HUMAN STK17A Serine/threonine-protein kinase 17A 1.093e-09 0.38
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 1.107e-09 0.34
SMO_MOUSE Smo Smoothened homolog 1.139e-09 0.35
NCOA1_HUMAN NCOA1 Nuclear receptor coactivator 1 1.215e-09 0.37
TERT_HUMAN TERT Telomerase reverse transcriptase 1.245e-09 0.47
BRPF1_HUMAN BRPF1 Peregrin 1.253e-09 0.37
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 1.349e-09 0.35
IL6_HUMAN IL6 Interleukin-6 1.431e-09 0.38
FA10_HUMAN F10 Coagulation factor X 1.605e-09 0.40
PAR1_HUMAN F2R Proteinase-activated receptor 1 1.953e-09 0.39
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 2.43e-09 0.46
RARB_HUMAN RARB Retinoic acid receptor beta 2.684e-09 0.41
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 2.775e-09 0.33
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 2.999e-09 0.37
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 3.097e-09 0.34
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 3.452e-09 0.33
INSR_MOUSE Insr Insulin receptor 3.496e-09 0.35
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 3.579e-09 0.33
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 3.856e-09 0.34
AURKB_HUMAN AURKB Aurora kinase B 3.93e-09 0.40
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 4.995e-09 0.32
SCRB1_MOUSE Scarb1 Scavenger receptor class B member 1 5.217e-09 0.35
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 5.519e-09 0.47
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 5.794e-09 0.34
O61059_LEIME LmGT2 Glucose transporter 5.847e-09 0.34
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 6.025e-09 0.38
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 6.333e-09 0.44
O77078_PLAFA fabH Beta-ketoacyl-acyl carrier protein synthase III 7.778e-09 0.29
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 7.844e-09 0.38
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 8.226e-09 0.37
RCE1_YEAST RCE1 CAAX prenyl protease 2 9.707e-09 0.36
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 1.043e-08 0.33
TTHY_HUMAN TTR Transthyretin 1.057e-08 0.32
LEF_BACAN lef Lethal factor 1.097e-08 0.38
KPCB_HUMAN PRKCB Protein kinase C beta type 1.237e-08 0.32
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.283e-08 0.41
CH10_HUMAN HSPE1 10 kDa heat shock protein, mitochondrial 1.566e-08 0.28
CH60_HUMAN HSPD1 60 kDa heat shock protein, mitochondrial 1.566e-08 0.28
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 1.756e-08 0.36
CATL2_HUMAN CTSV Cathepsin L2 1.775e-08 0.34
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 1.818e-08 0.36
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.942e-08 0.35
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 2.214e-08 0.38
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 2.237e-08 0.30
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 2.284e-08 0.33
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 2.314e-08 0.38
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 2.387e-08 0.30
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 2.835e-08 0.36
O97467_PLAFA ht1 Hexose transporter 1 2.84e-08 0.34
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 2.878e-08 0.38
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 3.151e-08 0.38
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 3.173e-08 0.35
DYN1_HUMAN DNM1 Dynamin-1 3.224e-08 0.28
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 3.409e-08 0.47
KCC2G_HUMAN CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 3.596e-08 0.32
GLI1_MOUSE Gli1 Zinc finger protein GLI1 3.65e-08 0.44
CASP6_HUMAN CASP6 Caspase-6 3.714e-08 0.40
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 4.622e-08 0.37
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 5.997e-08 0.32
CAN_CANAL NCE103 Carbonic anhydrase 6.78e-08 0.33
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 6.915e-08 0.32
AA3R_HUMAN ADORA3 Adenosine receptor A3 7.07e-08 0.41
FACE2_HUMAN RCE1 CAAX prenyl protease 2 7.504e-08 0.36
SKN1_CAEEL skn-1 Protein skinhead-1 7.932e-08 0.30
KHK_HUMAN KHK Ketohexokinase 7.963e-08 0.36
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 8.95e-08 0.43
GRM1_HUMAN GRM1 Metabotropic glutamate receptor 1 9.153e-08 0.40
DOPO_HUMAN DBH Dopamine beta-hydroxylase 1.031e-07 0.29
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.05e-07 0.35
AGTRA_RAT Agtr1 Type-1A angiotensin II receptor 1.079e-07 0.36
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.139e-07 0.33
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 1.327e-07 0.35
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 1.388e-07 0.34
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 1.397e-07 0.31
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 1.433e-07 0.35
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 1.779e-07 0.33
KPCD_HUMAN PRKCD Protein kinase C delta type 1.794e-07 0.32
PA_I34A1 PA Polymerase acidic protein 1.81e-07 0.31
RARG_HUMAN RARG Retinoic acid receptor gamma 1.828e-07 0.41
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 1.86e-07 0.53
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 1.978e-07 0.39
KCC2B_HUMAN CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta 2.272e-07 0.32
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 2.383e-07 0.39
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 2.98e-07 0.32
SHH_HUMAN SHH Sonic hedgehog protein 3.122e-07 0.32
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 3.313e-07 0.32
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 3.563e-07 0.34
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 3.625e-07 0.37
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 3.68e-07 0.31
KPCA_HUMAN PRKCA Protein kinase C alpha type 3.924e-07 0.33
PTN22_HUMAN PTPN22 Tyrosine-protein phosphatase non-receptor type 22 4.244e-07 0.30
CBP_HUMAN CREBBP CREB-binding protein 4.245e-07 0.40
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 4.372e-07 0.42
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 4.372e-07 0.42
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 4.413e-07 0.39
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 4.562e-07 0.31
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 4.644e-07 0.35
CAH15_MOUSE Ca15 Carbonic anhydrase 15 4.849e-07 0.30
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 4.948e-07 0.35
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 5.073e-07 0.37
CAH4_BOVIN CA4 Carbonic anhydrase 4 5.174e-07 0.51
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 5.702e-07 0.32
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 5.972e-07 0.30
TYSY_ECOLI thyA Thymidylate synthase 7.019e-07 0.29
Q8MI13_BOVIN 5htr1d 5-hydroxytryptamine 1D receptor 7.538e-07 0.30
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 7.895e-07 0.33
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 7.96e-07 0.33
TYDP2_HUMAN TDP2 Tyrosyl-DNA phosphodiesterase 2 8.014e-07 0.33
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 8.504e-07 0.35
NEUR3_HUMAN NEU3 Sialidase-3 8.63e-07 0.31
HKDC1_HUMAN HKDC1 Hexokinase HKDC1 9.119e-07 0.36
NSD2_HUMAN NSD2 Histone-lysine N-methyltransferase NSD2 9.298e-07 0.33
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 9.84e-07 0.43
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 1.005e-06 0.39
DYRK4_HUMAN DYRK4 Dual specificity tyrosine-phosphorylation-regulated kinase 4 1.15e-06 0.31
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 1.198e-06 0.28
NOX4_HUMAN NOX4 NADPH oxidase 4 1.201e-06 0.42
ARBK1_HUMAN GRK2 Beta-adrenergic receptor kinase 1 1.221e-06 0.35
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 1.246e-06 0.33
O49150_SOLTU Lipoxygenase 1.309e-06 0.33
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 1.34e-06 0.34
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.383e-06 0.34
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.425e-06 0.34
BTK_HUMAN BTK Tyrosine-protein kinase BTK 1.691e-06 0.37
KPYK_STAAR pyk Pyruvate kinase 1.72e-06 0.31
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 1.781e-06 0.32
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 1.816e-06 0.30
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 1.876e-06 0.33
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.959e-06 0.29
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 2.148e-06 0.37
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 2.158e-06 0.37
PTPRG_HUMAN PTPRG Receptor-type tyrosine-protein phosphatase gamma 2.369e-06 0.29
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 2.49e-06 0.40
PAX8_HUMAN PAX8 Paired box protein Pax-8 2.637e-06 0.37
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 2.667e-06 0.34
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 2.764e-06 0.37
DYRK3_HUMAN DYRK3 Dual specificity tyrosine-phosphorylation-regulated kinase 3 2.807e-06 0.35
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 2.838e-06 0.32
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 3.04e-06 0.53
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 3.068e-06 0.30
LMP1_EBVB9 LMP1 Latent membrane protein 1 3.193e-06 0.30
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 3.477e-06 0.28
LCK_MOUSE Lck Proto-oncogene tyrosine-protein kinase LCK 3.546e-06 0.38
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 3.584e-06 0.38
GRK5_HUMAN GRK5 G protein-coupled receptor kinase 5 3.589e-06 0.37
Q8MWR1_SPOFR USP Ultraspiracle protein 3.628e-06 0.31
Q8MWR2_SPOFR EcR Ecdysteroid receptor 3.628e-06 0.31
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 3.847e-06 0.29
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 4.034e-06 0.40
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 4.246e-06 0.31
CXCR2_HUMAN CXCR2 C-X-C chemokine receptor type 2 4.476e-06 0.35
PAG_BACAN pagA Protective antigen 4.555e-06 0.37
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 5.02e-06 0.29
AAPK1_HUMAN PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 5.167e-06 0.37
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 5.264e-06 0.32
NCOA3_HUMAN NCOA3 Nuclear receptor coactivator 3 5.499e-06 0.37
BRSK1_HUMAN BRSK1 Serine/threonine-protein kinase BRSK1 5.5e-06 0.31
PPCE_PIG PREP Prolyl endopeptidase 5.536e-06 0.31
RHOA_HUMAN RHOA Transforming protein RhoA 5.601e-06 0.34
MATK_HUMAN MATK Megakaryocyte-associated tyrosine-protein kinase 5.886e-06 0.29
CAH14_HUMAN CA14 Carbonic anhydrase 14 5.964e-06 0.32
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 6.06e-06 0.32
HXK4_HUMAN GCK Hexokinase-4 6.438e-06 0.31
ACES_MOUSE Ache Acetylcholinesterase 6.731e-06 0.37
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 7.519e-06 0.41
KISSR_HUMAN KISS1R KiSS-1 receptor 8.118e-06 0.33
Q8IL11_PLAF7 M17 leucyl aminopeptidase 8.222e-06 0.39
MINK1_HUMAN MINK1 Misshapen-like kinase 1 8.24e-06 0.32
OPRX_HUMAN OPRL1 Nociceptin receptor 8.532e-06 0.35
GYRB_MYCSM gyrB DNA gyrase subunit B 9.074e-06 0.38

Carboprost

PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 7.962e-118 0.65
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 9.741e-91 0.65
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 6.841e-87 0.65
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 9.121e-76 0.65
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 9.732e-76 0.65
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 2.622e-75 0.66
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 9.86e-56 0.65
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 5.22e-39 0.66
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 1.514e-35 0.46
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 1.877e-28 0.46
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 5.561e-24 0.40
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 9.825e-24 0.47
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 1.703e-23 0.30
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 8.999e-23 0.65
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 5.553e-18 0.66
PI2R_HUMAN PTGIR Prostacyclin receptor 1.11e-16 0.46
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 4.441e-16 0.43
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 7.772e-16 0.40
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 1.332e-15 0.43
CNR1_RAT Cnr1 Cannabinoid receptor 1 2.109e-15 0.36
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.609e-14 0.43
TA2R_RAT Tbxa2r Thromboxane A2 receptor 9.392e-14 0.43
LOX15_PIG ALOX15 Arachidonate 15-lipoxygenase 2.697e-13 0.30
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 3.445e-13 0.36
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 4.251e-12 0.30
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 7.466e-12 0.40
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.789e-11 0.65
MGLL_RAT Mgll Monoglyceride lipase 1.379e-10 0.31
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 2.926e-08 0.66
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 6.174e-08 0.29
GPR18_HUMAN GPR18 N-arachidonyl glycine receptor 2.042e-07 0.34
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 3.933e-06 0.30

Ciprocinonide

ATTY_RAT Tat Tyrosine aminotransferase 4.73e-102 0.38
GCR_RAT Nr3c1 Glucocorticoid receptor 2.347e-81 0.64
Q690N0_BOVIN PGR Progesterone receptor 9.401e-69 0.84
GCR_HUMAN NR3C1 Glucocorticoid receptor 1.575e-35 0.84
GCR_MOUSE Nr3c1 Glucocorticoid receptor 2.028e-10 0.59

Zongertinib

BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 5.702e-97 0.46
DUS2L_HUMAN DUS2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like 3.568e-41 0.33
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 1.187e-32 0.41
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 1.578e-29 0.32
EGFR_HUMAN EGFR Epidermal growth factor receptor 3.943e-27 0.37
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 1.026e-20 0.33
TGM2_MOUSE Tgm2 Protein-glutamine gamma-glutamyltransferase 2 1.523e-18 0.29
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 1.127e-13 0.32
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 1.972e-10 0.35
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 2.084e-08 0.30
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 3.657e-07 0.33
PDE6C_HUMAN PDE6C Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' 6.265e-07 0.31
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 4.706e-06 0.34

Procinonide

ATTY_RAT Tat Tyrosine aminotransferase 2.98e-96 0.36
GCR_RAT Nr3c1 Glucocorticoid receptor 1.783e-82 0.65
Q690N0_BOVIN PGR Progesterone receptor 8.62e-69 0.86
GCR_HUMAN NR3C1 Glucocorticoid receptor 6.589e-34 0.86
GCR_MOUSE Nr3c1 Glucocorticoid receptor 3.142e-10 0.58

Enmetazobactam

BLAC_BACLI penP Beta-lactamase 1.981e-95 0.56
A1E3K9_ECOLX blaSCO-1 Beta-lactamase 9.128e-79 0.56
A8RR46_BACCS bcl1 Beta-lactamase 9.128e-79 0.56
D2SSQ3_PSEAI Beta-lactamase 9.128e-79 0.56
Q3SAW3_PSEAI bla(BEL1) Beta-lactamase 9.128e-79 0.56
AMPC_CITFR ampC Beta-lactamase 4.254e-78 0.56
A0ZX81_KLEPN blaSHV-72 Beta-lactamase 6.785e-70 0.56
A4KCT8_9ENTR BlaGIL-1 Beta-lactamase 6.785e-70 0.56
AMPC_MORMO ampC Beta-lactamase 6.785e-70 0.56
B8R6A5_9BURK penB1 Beta-lactamase 6.785e-70 0.56
BLKPC_KLEPN bla Carbapenem-hydrolyzing beta-lactamase KPC 6.785e-70 0.56
BLO1_ECOLX bla Beta-lactamase OXA-1 6.785e-70 0.56
Q2XPY6_SALET blaCTX-M-53 Beta-lactamase 6.785e-70 0.56
Q50H31_BRAPL oxa-63 Class D beta-lactamase 6.785e-70 0.56
Q670S6_PSELU Beta-lactamase 6.785e-70 0.56
Q6GWS8_ECOLX blaTEM-125 Beta-lactamase 6.785e-70 0.56
Q6JP75_SERFO Beta-lactamase 6.785e-70 0.56
Q9EXV5_ECOLX blaUOE-1 Beta-lactamase 6.785e-70 0.56
D1MIX9_PSEAI blaGES-13 Beta-lactamase 1.299e-60 0.56
Q53729_STAAU PBP2 Penicillin-binding protein 2 8.585e-57 0.45
D5HSX5_9GAMM blaPER-6 Beta-lactamase 1.986e-54 0.43
Q0VTR6_ACIPI adc-14 Beta-lactamase 1.986e-54 0.43
Q0VTR8_ACIPI adc-16 Beta-lactamase 1.986e-54 0.43
Q7X575_ECOLX SHV-11 Beta-lactamase 1.986e-54 0.43
BLA1_KLEPN bla Beta-lactamase SHV-1 9.9e-45 0.56
AMPC_ENTCL ampC Beta-lactamase 2.848e-26 0.56
A2RP81_CITFR blaPER-2 Beta-lactamase 6.362e-25 0.56
Q46991_ENTCL imiA Beta-lactamase 6.362e-25 0.56
Q3S5C3_SALNE sugE Efflux transporter 1.803e-22 0.36
Q48435_KLEPN bla LAT-2 Beta-lactamase 1.803e-22 0.36
BLAC_STAAU blaZ Beta-lactamase 1.783e-18 0.56
AMPC_PSEAE ampC Beta-lactamase 1.11e-16 0.56
BLAT_ECOLX bla; blaT-3; blaT-4; blaT-5; blaT-6 Beta-lactamase TEM 2.22e-15 0.56
BLA1_ECOLX bla Beta-lactamase SHV-1 1.187e-11 0.56
Q6W9J1_ENTCL blaTEM-1 Beta-lactamase 1.434e-11 0.56
Q59401_ENTCL Beta-lactamase 1.469e-07 0.56
AMPC_ECOLI ampC Beta-lactamase 6.397e-06 0.56

Pentapiperium

GPR88_HUMAN GPR88 Probable G-protein coupled receptor 88 3.247e-92 0.34
Q8VH25_CAVPO GPM4 Muscarinic acetylcholine receptor 8.195e-50 0.40
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 2.008e-41 0.67
Q8WSF8_APLCA Soluble acetylcholine receptor 3.966e-41 0.37
ACER2_HUMAN ACER2 Alkaline ceramidase 2 1.52e-40 0.32
AMYP_RAT Amy2 Pancreatic alpha-amylase 2.765e-40 0.31
GPR88_MOUSE Gpr88 Probable G-protein coupled receptor 88 2.095e-36 0.29
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 8.815e-33 0.67
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 4.993e-29 0.67
ACHP_LYMST Acetylcholine-binding protein 1.055e-23 0.37
E1BI31_BOVIN DPP9 Dipeptidyl peptidase 9 2.784e-21 0.34
ACE_MOUSE Ace Angiotensin-converting enzyme 2.929e-20 0.32
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.507e-19 0.67
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 8.821e-19 0.35
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 1.77e-18 0.67
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 2.647e-18 0.67
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.687e-17 0.67
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 2.242e-17 0.67
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 2.4e-17 0.67
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 2.22e-16 0.67
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 2.22e-16 0.32
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 3.331e-16 0.40
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 1.11e-15 0.29
K4JQ36_LAOST ace2 Carboxylic ester hydrolase 2.442e-15 0.29
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 2.898e-14 0.35
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 9.17e-14 0.30
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 1.372e-13 0.30
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 1.688e-13 0.29
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 3.959e-13 0.32
PDS_SYNE7 pds 15-cis-phytoene desaturase 1.84e-12 0.29
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 5.427e-12 0.29
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 5.427e-12 0.29
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 1.36e-11 0.45
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 1.507e-11 0.29
CATL2_HUMAN CTSV Cathepsin L2 2.9e-11 0.31
Q8WMX0_BOVIN Muscarinic receptor M1 4.237e-11 0.40
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 6.536e-11 0.29
Q7YWJ9_MUSDO Ache Carboxylic ester hydrolase 7.306e-11 0.29
Q9NJH6_NEPCI AO-AChE Ace-orthologous acetylcholinesterase 7.306e-11 0.29
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 7.385e-11 0.29
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 8.912e-10 0.30
BLAB_AERHY cphA Metallo-beta-lactamase type 2 1.37e-09 0.30
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 3.598e-09 0.29
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 3.952e-09 0.38
NEP_RABIT MME Neprilysin 4.521e-09 0.34
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 1.104e-08 0.31
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 1.744e-08 0.40
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 2.222e-08 0.30
KPCA_MOUSE Prkca Protein kinase C alpha type 2.676e-08 0.32
O31048_PORGN DPP IV Dipeptidyl peptidase IV 4.686e-08 0.34
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 1.197e-07 0.30
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 1.291e-07 0.28
CBPA1_HUMAN CPA1 Carboxypeptidase A1 3.169e-07 0.29
MRGX1_HUMAN MRGPRX1 Mas-related G-protein coupled receptor member X1 4.004e-07 0.29
AMPL_PIG LAP3 Cytosol aminopeptidase 5.981e-07 0.38
VKOR1_RAT Vkorc1 Vitamin K epoxide reductase complex subunit 1 6.322e-07 0.28
PI2R_HUMAN PTGIR Prostacyclin receptor 9.386e-07 0.33
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 9.412e-07 0.30
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 9.642e-07 0.29
SCYD_MAGO7 SDH1 Scytalone dehydratase 9.835e-07 0.29
Q8VH27_CAVPO GPM2 Muscarinic acetylcholine receptor 1.131e-06 0.40
ACE_RAT Ace Angiotensin-converting enzyme 1.179e-06 0.34
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 1.275e-06 0.44
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 1.954e-06 0.29
AOC3_HUMAN AOC3 Membrane primary amine oxidase 2.489e-06 0.33
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 3.177e-06 0.47
CBPA1_BOVIN CPA1 Carboxypeptidase A1 3.585e-06 0.33
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 3.749e-06 0.32
NR1H4_MOUSE Nr1h4 Bile acid receptor 5.7e-06 0.28
CATK_HUMAN CTSK Cathepsin K 6.06e-06 0.31
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 6.954e-06 0.67
ACHB2_RAT Chrnb2 Neuronal acetylcholine receptor subunit beta-2 7.862e-06 0.35
NEP_HUMAN MME Neprilysin 9.645e-06 0.32

Megestrol

CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 9.703e-89 0.59
Q690N0_BOVIN PGR Progesterone receptor 1.194e-71 0.70
SHBG_HUMAN SHBG Sex hormone-binding globulin 2.342e-53 0.59
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 3.578e-51 0.35
CP19A_HUMAN CYP19A1 Aromatase 3.183e-41 0.63
PRGR_RAT Pgr Progesterone receptor 3.184e-41 0.34
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.628e-39 0.33
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 1.023e-37 0.32
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 6.162e-32 0.35
GCR_MOUSE Nr3c1 Glucocorticoid receptor 8.585e-29 0.41
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 5.157e-24 0.37
SHBG_RAT Shbg Sex hormone-binding globulin 4.185e-23 0.28
ANDR_RAT Ar Androgen receptor 1.011e-22 0.70
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 2.162e-21 0.34
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.362e-20 0.37
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 6e-20 0.32
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 7.902e-18 0.40
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 5.218e-15 0.35
PRGR_RABIT PGR Progesterone receptor 1.854e-14 0.38
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 6.795e-14 0.37
GCR_HUMAN NR3C1 Glucocorticoid receptor 1.494e-13 0.70
ANDR_MOUSE Ar Androgen receptor 9.589e-12 0.39
MCR_HUMAN NR3C2 Mineralocorticoid receptor 6.778e-10 0.41
GLNA_HUMAN GLUL Glutamine synthetase 7.039e-10 0.31
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 9.192e-10 0.37
ANDR_HUMAN AR Androgen receptor 2.831e-09 0.39
ERG2_YEAST ERG2 C-8 sterol isomerase 3.582e-09 0.37
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 5.305e-08 0.32
IL6_HUMAN IL6 Interleukin-6 6.548e-08 0.31
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.128e-06 0.40
PRGR_HUMAN PGR Progesterone receptor 2.902e-06 0.39
AT1A4_RAT Atp1a4 Sodium/potassium-transporting ATPase subunit alpha-4 5.668e-06 0.30
AT1B1_RAT Atp1b1 Sodium/potassium-transporting ATPase subunit beta-1 5.668e-06 0.30

Lomifylline

AA2AR_CAVPO ADORA2A Adenosine receptor A2a 6.72e-87 0.62
CNOT7_HUMAN CNOT7 CCR4-NOT transcription complex subunit 7 6.076e-80 0.47
CHIB1_ASPFM chiB1 Endochitinase B1 2.215e-75 0.45
PAOX_HUMAN PAOX Peroxisomal N(1)-acetyl-spermine/spermidine oxidase 6.523e-47 0.31
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 1.699e-43 0.33
AA2AR_RAT Adora2a Adenosine receptor A2a 2.966e-30 0.62
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 2.258e-21 0.38
AA1R_RAT Adora1 Adenosine receptor A1 6.125e-21 0.62
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 6.589e-19 0.46
AA1R_CAVPO ADORA1 Adenosine receptor A1 1.879e-18 0.57
AMPD1_HUMAN AMPD1 AMP deaminase 1 3.488e-18 0.29
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 2.22e-16 0.34
ADCY5_HUMAN ADCY5 Adenylate cyclase type 5 5.251e-14 0.33
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 1.62e-13 0.38
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 4.483e-13 0.50
AMPD2_HUMAN AMPD2 AMP deaminase 2 6.733e-12 0.29
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 7.711e-11 0.55
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 2.854e-10 0.55
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 2.865e-10 0.32
AA2BR_RAT Adora2b Adenosine receptor A2b 4.327e-10 0.62
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 7.797e-10 0.55
NCOA3_HUMAN NCOA3 Nuclear receptor coactivator 3 1.751e-08 0.33
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 2.139e-08 0.69
ADA_BOVIN ADA Adenosine deaminase 2.64e-08 0.30
REV1_HUMAN REV1 DNA repair protein REV1 2.827e-08 0.31
TNFA_HUMAN TNF Tumor necrosis factor 4.459e-08 0.41
CHIA_MOUSE Chia Acidic mammalian chitinase 7.658e-08 0.42
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 1.137e-07 0.33
AA3R_RAT Adora3 Adenosine receptor A3 5.565e-07 0.33
AA1R_BOVIN ADORA1 Adenosine receptor A1 9.945e-07 0.36
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 2.375e-06 0.57
HPRT_HUMAN HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 3.55e-06 0.28
PNPH_RAT Pnp Purine nucleoside phosphorylase 5.091e-06 0.28
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 5.254e-06 0.31

Imlunestrant

ESR1_HUMAN ESR1 Estrogen receptor 1.075e-79 0.43
ESR2_HUMAN ESR2 Estrogen receptor beta 1.091e-78 0.43
ESR1_RAT Esr1 Estrogen receptor 2.184e-18 0.31
ESR2_RAT Esr2 Estrogen receptor beta 4.842e-17 0.31
PPARA_CANLF PPARA Peroxisome proliferator-activated receptor alpha 6.084e-10 0.28
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 6.62e-10 0.29
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 9.396e-07 0.29

Aficamten

KNG1_HUMAN KNG1 Kininogen-1 2.61e-78 0.39
BKRB1_RABIT BDKRB1 B1 bradykinin receptor 4.104e-48 0.33
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 1.561e-40 0.35
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 8.479e-38 0.36
HDAC4_HUMAN HDAC4 Histone deacetylase 4 9.828e-33 0.37
BKRB1_HUMAN BDKRB1 B1 bradykinin receptor 2.031e-21 0.34
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 3.608e-20 0.34
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 4.656e-20 0.34
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 6.852e-18 0.32
ETHR_MYCTU ethR HTH-type transcriptional regulator EthR 2.22e-16 0.31
GRM5_HUMAN GRM5 Metabotropic glutamate receptor 5 2.22e-16 0.33
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 2.22e-16 0.32
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 3.331e-16 0.32
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 7.55e-15 0.37
S1PR1_RAT S1pr1 Sphingosine 1-phosphate receptor 1 2.931e-14 0.30
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 1.246e-13 0.37
TTK_HUMAN TTK Dual specificity protein kinase TTK 1.433e-13 0.31
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 2.708e-13 0.32
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 4.304e-12 0.34
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 8.187e-10 0.34
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 3.571e-09 0.31
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 3.588e-09 0.35
HDAC6_HUMAN HDAC6 Histone deacetylase 6 5.429e-08 0.37
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 4.015e-07 0.34
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 9.153e-07 0.31
S1PR1_MOUSE S1pr1 Sphingosine 1-phosphate receptor 1 9.689e-07 0.30
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 1.131e-06 0.32
TNFA_HUMAN TNF Tumor necrosis factor 2.668e-06 0.34
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 8.365e-06 0.30
COT2_HUMAN NR2F2 COUP transcription factor 2 8.372e-06 0.31
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 9.147e-06 0.34

Parethoxycaine

CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 8.905e-73 0.43
DCOR_MOUSE Odc1 Ornithine decarboxylase 3.416e-72 0.34
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 7.947e-63 0.37
AMYP_RAT Amy2 Pancreatic alpha-amylase 2.675e-61 0.43
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.088e-59 0.54
KDM6A_HUMAN KDM6A Lysine-specific demethylase 6A 5.596e-51 0.34
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 3.62e-46 0.31
SAT1_HUMAN SAT1 Diamine acetyltransferase 1 5.166e-42 0.33
ACRO_PIG ACR Acrosin 4.83e-36 0.33
Q8WMX0_BOVIN Muscarinic receptor M1 2.715e-34 0.43
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 6.371e-34 0.55
ACRO_HUMAN ACR Acrosin 1.182e-33 0.40
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 4.175e-31 0.30
ERG2_YEAST ERG2 C-8 sterol isomerase 2.352e-30 0.55
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 8.227e-28 0.47
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 8.158e-26 0.40
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 4.902e-25 0.32
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 5.689e-25 0.39
IKKB_MOUSE Ikbkb Inhibitor of nuclear factor kappa-B kinase subunit beta 1.566e-24 0.38
HRH3_RAT Hrh3 Histamine H3 receptor 6.676e-23 0.45
Q4Q5W4_LEIMA Putative squalene synthase 1.962e-21 0.35
AOC1_HUMAN AOC1 Amiloride-sensitive amine oxidase [copper-containing] 2.296e-21 0.33
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 8.254e-20 0.30
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.806e-19 0.43
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 2.925e-19 0.41
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 1.014e-18 0.31
NADE_BACSU nadE NH(3)-dependent NAD(+) synthetase 8.52e-18 0.28
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 1.106e-17 0.39
A0A0Y9T855_PLABE DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.11e-16 0.37
A5K1N1_PLAVS Dihydroorotate dehydrogenase, mitochondrial, putative 1.11e-16 0.37
PAR16_HUMAN PARP16 Protein mono-ADP-ribosyltransferase PARP16 8.882e-16 0.30
ERG1_RAT Sqle Squalene monooxygenase 1.221e-15 0.33
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.332e-15 0.39
HRH2_HUMAN HRH2 Histamine H2 receptor 1.887e-15 0.34
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.109e-15 0.30
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 4.663e-15 0.35
HNF4A_RAT Hnf4a Hepatocyte nuclear factor 4-alpha 1.454e-14 0.30
CHLE_HORSE BCHE Cholinesterase 1.743e-14 0.41
ACACB_HUMAN ACACB Acetyl-CoA carboxylase 2 2.831e-14 0.35
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 3.042e-14 0.43
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 4.43e-14 0.31
OPRM_MACMU OPRM1 Mu-type opioid receptor 5.851e-14 0.34
STS_HUMAN STS Steryl-sulfatase 7.572e-14 0.43
CP26B_HUMAN CYP26B1 Cytochrome P450 26B1 1.936e-13 0.30
A3KMY8_BOVIN GUSB Beta-glucuronidase 2.177e-13 0.33
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 2.534e-13 0.34
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 2.986e-13 0.29
RARB_HUMAN RARB Retinoic acid receptor beta 4.218e-13 0.36
LSS_HUMAN LSS Lanosterol synthase 4.728e-13 0.33
PRIO_SHEEP PRNP Major prion protein 6.177e-13 0.32
HRH1_HUMAN HRH1 Histamine H1 receptor 7.017e-13 0.35
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 8.085e-13 0.33
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 1.257e-12 0.49
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 1.272e-12 0.44
Q8MMZ4_PLAFA cGMP-dependent protein kinase 2.757e-12 0.30
HNF4A_HUMAN HNF4A Hepatocyte nuclear factor 4-alpha 7.633e-12 0.30
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 9.063e-12 0.42
RARA_HUMAN RARA Retinoic acid receptor alpha 9.538e-12 0.36
S100B_HUMAN S100B Protein S100-B 2.335e-11 0.33
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 3.355e-11 0.35
RBBP9_HUMAN RBBP9 Serine hydrolase RBBP9 5.659e-11 0.29
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 5.746e-11 0.47
CAH2_BOVIN CA2 Carbonic anhydrase 2 6.433e-11 0.34
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 8.116e-11 0.32
ACES_ELEEL ache Acetylcholinesterase 1.122e-10 0.40
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 1.441e-10 0.33
B2LA1_MOUSE Bcl2a1 Bcl-2-related protein A1 2.225e-10 0.42
PRTN3_HUMAN PRTN3 Myeloblastin 4.64e-10 0.30
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 6.972e-10 0.40
NORA_STAAU norA Quinolone resistance protein NorA 7.28e-10 0.33
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 7.382e-10 0.30
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 1.073e-09 0.33
AHR_RABIT AHR Aryl hydrocarbon receptor 1.136e-09 0.30
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.349e-09 0.35
KAT2A_HUMAN KAT2A Histone acetyltransferase KAT2A 2.108e-09 0.31
PHOP1_HUMAN PHOSPHO1 Phosphoethanolamine/phosphocholine phosphatase 2.181e-09 0.50
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 2.228e-09 0.43
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 2.755e-09 0.33
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 2.783e-09 0.42
CA2D2_HUMAN CACNA2D2 Voltage-dependent calcium channel subunit alpha-2/delta-2 3.409e-09 0.30
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 3.598e-09 0.29
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 4.97e-09 0.43
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 6.585e-09 0.36
PAR14_HUMAN PARP14 Protein mono-ADP-ribosyltransferase PARP14 6.929e-09 0.30
ESR1_HUMAN ESR1 Estrogen receptor 7.097e-09 0.47
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 9.129e-09 0.35
THA_HUMAN THRA Thyroid hormone receptor alpha 1.302e-08 0.41
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.898e-08 0.60
RXRG_MOUSE Rxrg Retinoic acid receptor RXR-gamma 2.246e-08 0.32
Q8IL11_PLAF7 M17 leucyl aminopeptidase 2.649e-08 0.34
KLKB1_HUMAN KLKB1 Plasma kallikrein 2.752e-08 0.35
RXRB_MOUSE Rxrb Retinoic acid receptor RXR-beta 3.294e-08 0.32
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 4.348e-08 0.47
SRC_MOUSE Src Neuronal proto-oncogene tyrosine-protein kinase Src 4.723e-08 0.29
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 4.736e-08 0.37
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 4.798e-08 0.47
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 6.82e-08 0.31
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 7.53e-08 0.37
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 9.145e-08 0.30
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 9.429e-08 0.33
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 1.064e-07 0.30
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 1.124e-07 0.31
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 1.436e-07 0.42
LUCI_PHOPY Luciferin 4-monooxygenase 2.009e-07 0.44
KLK1_HUMAN KLK1 Kallikrein-1 2.163e-07 0.30
PLMN_RAT Plg Plasminogen 2.517e-07 0.30
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 3.271e-07 0.39
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.409e-07 0.33
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 3.41e-07 0.43
CDKA1_HUMAN CDK2AP1 Cyclin-dependent kinase 2-associated protein 1 6.332e-07 0.32
TRY1_HUMAN PRSS1 Trypsin-1 6.884e-07 0.40
GBRB_MUSDO Rdl Gamma-aminobutyric acid receptor subunit beta 7.608e-07 0.34
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 8.917e-07 0.38
O61059_LEIME LmGT2 Glucose transporter 9.127e-07 0.37
PDS_SYNE7 pds 15-cis-phytoene desaturase 1.192e-06 0.31
CAH7_HUMAN CA7 Carbonic anhydrase 7 1.223e-06 0.44
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 1.26e-06 0.34
CHLE_HUMAN BCHE Cholinesterase 1.463e-06 0.44
RORA_HUMAN RORA Nuclear receptor ROR-alpha 1.515e-06 0.32
SCN3A_HUMAN SCN3A Sodium channel protein type 3 subunit alpha 1.521e-06 0.43
HRH3_HUMAN HRH3 Histamine H3 receptor 2.07e-06 0.45
AGP1_YEAST AGP1 General amino acid permease AGP1 2.128e-06 0.31
CNR2_HUMAN CNR2 Cannabinoid receptor 2 2.441e-06 0.36
CAH14_HUMAN CA14 Carbonic anhydrase 14 2.722e-06 0.44
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 2.986e-06 0.31
BMP4_HUMAN BMP4 Bone morphogenetic protein 4 3.78e-06 0.31
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 4.212e-06 0.47
THAS_HUMAN TBXAS1 Thromboxane-A synthase 4.573e-06 0.33
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 4.579e-06 0.33
O97467_PLAFA ht1 Hexose transporter 1 4.805e-06 0.37
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 4.908e-06 0.33
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 5.641e-06 0.36
FFAR4_MOUSE Ffar4 Free fatty acid receptor 4 5.692e-06 0.33
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 6.457e-06 0.30
RARG_HUMAN RARG Retinoic acid receptor gamma 8.357e-06 0.36
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 9.782e-06 0.47

Aurothioglycanide

ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 4.937e-70 0.46
RCOR3_HUMAN RCOR3 REST corepressor 3 1.91e-64 0.52
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.439e-59 0.36
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 1.892e-45 0.52
NADD_BACAC nadD Probable nicotinate-nucleotide adenylyltransferase 2.944e-45 0.28
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 8e-41 0.35
NCS1_HUMAN NCS1 Neuronal calcium sensor 1 1.572e-36 0.29
Q9VWX8_DROME Frq2 FI18190p1 1.572e-36 0.29
HDAC8_HUMAN HDAC8 Histone deacetylase 8 3.596e-34 0.52
EPHB_MYCTO Epoxide hydrolase B 3.023e-33 0.54
Q7K6A1_PLAF7 Histone deacetylase 7.638e-32 0.52
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 1.485e-31 0.39
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 2.902e-30 0.38
HDAC1_HUMAN HDAC1 Histone deacetylase 1 5.488e-30 0.52
NEDD4_HUMAN NEDD4 E3 ubiquitin-protein ligase NEDD4 7.553e-30 0.37
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 1.132e-29 0.41
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 2.006e-29 0.52
A5H660_SCHMA HDAC8 Histone deacetylase 8 6.174e-29 0.52
HDAC2_HUMAN HDAC2 Histone deacetylase 2 2.363e-28 0.52
PRIO_SHEEP PRNP Major prion protein 1.521e-27 0.38
Q38C41_TRYB2 Phosphotransferase 2.423e-27 0.41
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 5.926e-27 0.42
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 4.186e-26 0.42
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.744e-25 0.54
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 2.111e-25 0.31
CAH4_BOVIN CA4 Carbonic anhydrase 4 4.074e-25 0.39
BLAB_BACCE Metallo-beta-lactamase type 2 4.642e-25 0.28
MANBA_HUMAN MANBA Beta-mannosidase 7.143e-25 0.31
NOX1_HUMAN NOX1 NADPH oxidase 1 1.549e-24 0.42
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.807e-24 0.33
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 7.96e-23 0.42
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.037e-22 0.52
UT1_RAT Slc14a1 Urea transporter 1 1.208e-22 0.32
LIPL_RAT Lpl Lipoprotein lipase 2.345e-22 0.30
HDAC6_HUMAN HDAC6 Histone deacetylase 6 3.846e-22 0.52
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 5.443e-22 0.33
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 4.155e-21 0.39
FUCO_BOVIN FUCA1 Tissue alpha-L-fucosidase 5.728e-21 0.41
Q6FTL6_CANGA NCE103 Carbonic anhydrase 8.276e-21 0.39
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 9.509e-21 0.52
EST1_RABIT Liver carboxylesterase 1 2.973e-20 0.39
VE1_HPV11 E1 Replication protein E1 3.434e-20 0.40
HDA11_HUMAN HDAC11 Histone deacetylase 11 3.44e-20 0.52
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 5.747e-20 0.52
CAH2_HUMAN CA2 Carbonic anhydrase 2 9.67e-20 0.42
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 1.069e-19 0.33
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 1.148e-19 0.42
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 1.18e-19 0.41
O31272_9GAMM imiS Beta-lactamase 1.67e-19 0.35
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 2.584e-19 0.38
S27A1_MOUSE Slc27a1 Long-chain fatty acid transport protein 1 8.169e-19 0.33
AHK3_ARATH AHK3 Histidine kinase 3 9.915e-19 0.36
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 8.751e-18 0.41
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 1.682e-17 0.36
PA_I000X PA Polymerase acidic protein 1.882e-17 0.33
CAH1_HUMAN CA1 Carbonic anhydrase 1 3.138e-17 0.42
LUCI_AQULA Luciferin 4-monooxygenase 1.11e-16 0.30
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 2.22e-16 0.33
MYG_HUMAN MB Myoglobin 2.22e-16 0.31
TYRO_MOUSE Tyr Tyrosinase 4.441e-16 0.40
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 8.882e-16 0.44
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 9.992e-16 0.39
UREA_CANEN Urease 9.992e-16 0.36
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 1.221e-15 0.39
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.776e-15 0.42
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 1.887e-15 0.38
CAH9_HUMAN CA9 Carbonic anhydrase 9 3.775e-15 0.42
PAR12_HUMAN PARP12 Protein mono-ADP-ribosyltransferase PARP12 4.441e-15 0.29
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 4.774e-15 0.38
GYRA_STAAU gyrA DNA gyrase subunit A 5.218e-15 0.36
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 5.773e-15 0.30
PA_I34A1 PA Polymerase acidic protein 6.439e-15 0.33
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 1.488e-14 0.39
AHK4_ARATH AHK4 Histidine kinase 4 1.532e-14 0.36
BXE_CLOBO botE Botulinum neurotoxin type E 1.532e-14 0.36
FNTA_HUMAN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 1.688e-14 0.38
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 3.075e-14 0.39
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 4.952e-14 0.52
ISPT_STRPN uppS Isoprenyl transferase 6.217e-14 0.32
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 9.37e-14 0.33
PSBA_SPIOL psbA Photosystem II protein D1 9.426e-14 0.45
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.06e-13 0.52
PFKA_TRYCC pfk ATP-dependent 6-phosphofructokinase 1.947e-13 0.30
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 4.149e-13 0.38
CAN_CANAL NCE103 Carbonic anhydrase 5.644e-13 0.36
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 1.082e-12 0.39
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 1.329e-12 0.61
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 1.417e-12 0.35
PFKA_TRYBB pfk ATP-dependent 6-phosphofructokinase 1.505e-12 0.30
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 1.918e-12 0.52
ARBK2_HUMAN GRK3 Beta-adrenergic receptor kinase 2 2.359e-12 0.30
HDAC7_HUMAN HDAC7 Histone deacetylase 7 2.421e-12 0.52
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 3.82e-12 0.30
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 4.027e-12 0.33
FUCO_HUMAN FUCA1 Tissue alpha-L-fucosidase 4.562e-12 0.41
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 5.981e-12 0.44
MITF_HUMAN MITF Microphthalmia-associated transcription factor 6.278e-12 0.48
KLK2_HUMAN KLK2 Kallikrein-2 7.334e-12 0.29
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 9.7e-12 0.29
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 9.7e-12 0.29
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 1.045e-11 0.29
HDAC5_HUMAN HDAC5 Histone deacetylase 5 1.319e-11 0.52
LYOX_HUMAN LOX Protein-lysine 6-oxidase 1.375e-11 0.32
DNAB_MYCTU dnaB Replicative DNA helicase 1.666e-11 0.48
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 1.89e-11 0.39
Q9NBA7_PLAFA Cysteine protease falcipain-3 1.92e-11 0.31
EST2_HUMAN CES2 Cocaine esterase 4.005e-11 0.33
PPO2_AGABI PPO2 Polyphenol oxidase 2 4.139e-11 0.48
BLA2_BACCE blm Metallo-beta-lactamase type 2 6.132e-11 0.29
KLK8_HUMAN KLK8 Kallikrein-8 8.581e-11 0.29
HDAC4_HUMAN HDAC4 Histone deacetylase 4 9.958e-11 0.52
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.017e-10 0.41
H9B8T9_CAPHI CTSB Cathepsin B 1.196e-10 0.38
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.213e-10 0.29
RECA_MYCTU recA Protein RecA 1.22e-10 0.48
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 1.266e-10 0.32
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.39e-10 0.41
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 1.472e-10 0.36
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 1.501e-10 0.35
LYAM1_HUMAN SELL L-selectin 1.781e-10 0.36
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 2.822e-10 0.49
SENP7_HUMAN SENP7 Sentrin-specific protease 7 2.848e-10 0.47
RCOR1_HUMAN RCOR1 REST corepressor 1 2.929e-10 0.35
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 3.04e-10 0.42
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 3.04e-10 0.42
RNH1_HUMAN RNASEH1 Ribonuclease H1 3.705e-10 0.30
ACRO_HUMAN ACR Acrosin 3.844e-10 0.34
HDAC9_HUMAN HDAC9 Histone deacetylase 9 4.024e-10 0.52
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 4.752e-10 0.34
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 5.127e-10 0.38
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 5.277e-10 0.42
Q8IL11_PLAF7 M17 leucyl aminopeptidase 5.475e-10 0.33
KLK4_HUMAN KLK4 Kallikrein-4 5.982e-10 0.29
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 7.541e-10 0.29
S100B_HUMAN S100B Protein S100-B 7.541e-10 0.29
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 8.096e-10 0.38
SOAT1_CHLAE SOAT1 Sterol O-acyltransferase 1 9.46e-10 0.28
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 9.915e-10 0.32
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 1.194e-09 0.35
MMP1_HUMAN MMP1 Interstitial collagenase 1.873e-09 0.41
Q9JN24_ECOLX def Peptide deformylase 1.986e-09 0.33
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 2.381e-09 0.41
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 2.399e-09 0.37
GYRB_STAAU gyrB DNA gyrase subunit B 2.424e-09 0.36
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 2.44e-09 0.31
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 2.471e-09 0.30
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 2.64e-09 0.54
EST1_HUMAN CES1 Liver carboxylesterase 1 2.747e-09 0.33
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 2.919e-09 0.42
CAH7_HUMAN CA7 Carbonic anhydrase 7 3.288e-09 0.42
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 3.598e-09 0.29
PARP4_HUMAN PARP4 Protein mono-ADP-ribosyltransferase PARP4 3.598e-09 0.29
PSBA_MARPO psbA Photosystem II protein D1 4.608e-09 0.28
IL8_HUMAN CXCL8 Interleukin-8 4.756e-09 0.32
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 5.023e-09 0.31
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 5.367e-09 0.30
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 6.887e-09 0.32
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 9.079e-09 0.29
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 9.129e-09 0.52
PANK1_HUMAN PANK1 Pantothenate kinase 1 9.971e-09 0.31
LYAM3_HUMAN SELP P-selectin 1.181e-08 0.36
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.199e-08 0.35
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.232e-08 0.30
PAR14_HUMAN PARP14 Protein mono-ADP-ribosyltransferase PARP14 1.702e-08 0.29
FEN1_HUMAN FEN1 Flap endonuclease 1 1.77e-08 0.33
ITA3_HUMAN ITGA3 Integrin alpha-3 1.775e-08 0.30
PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 1.883e-08 0.33
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 2.021e-08 0.42
AGP1_YEAST AGP1 General amino acid permease AGP1 3.119e-08 0.42
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 5.39e-08 0.30
Q9XYC7_PLAFA HDAC1 Histone deacetylase 6.806e-08 0.52
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 7.192e-08 0.33
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.043e-07 0.48
TRYP_PIG Trypsin 1.068e-07 0.38
PAR1_HUMAN F2R Proteinase-activated receptor 1 1.103e-07 0.36
SOAT2_CHLAE SOAT2 Sterol O-acyltransferase 2 1.227e-07 0.28
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 1.724e-07 0.35
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 1.769e-07 0.29
I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 1.801e-07 0.38
MMP3_HUMAN MMP3 Stromelysin-1 1.975e-07 0.34
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 2.077e-07 0.29
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 2.085e-07 0.33
BCAT2_HUMAN BCAT2 Branched-chain-amino-acid aminotransferase, mitochondrial 2.463e-07 0.33
PYRD_RAT Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 2.507e-07 0.33
Q25615_ONCVO Chitinase 2.59e-07 0.30
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 2.869e-07 0.28
CAH4_HUMAN CA4 Carbonic anhydrase 4 3.032e-07 0.36
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 3.032e-07 0.31
DDIT3_HUMAN DDIT3 DNA damage-inducible transcript 3 protein 3.629e-07 0.29
UROK_HUMAN PLAU Urokinase-type plasminogen activator 3.88e-07 0.38
PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 4.16e-07 0.38
CBPB1_PIG CPB1 Carboxypeptidase B 4.177e-07 0.29
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 4.177e-07 0.29
NEP_RAT Mme Neprilysin 5.081e-07 0.32
HSF1_MOUSE Hsf1 Heat shock factor protein 1 5.69e-07 0.48
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 6.654e-07 0.34
POLG_DEN2P Genome polyprotein 6.707e-07 0.29
TAT_HV112 tat Protein Tat 7.091e-07 0.30
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 7.794e-07 0.36
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 8.032e-07 0.44
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 8.058e-07 0.29
SMO_HUMAN SMO Smoothened homolog 8.71e-07 0.38
NR1H4_HUMAN NR1H4 Bile acid receptor 9.012e-07 0.38
POLG_CXB3N Genome polyprotein 9.355e-07 0.29
SENP6_HUMAN SENP6 Sentrin-specific protease 6 1.183e-06 0.37
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 1.197e-06 0.37
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 1.247e-06 0.31
MAPK3_HUMAN MAPKAPK3 MAP kinase-activated protein kinase 3 1.288e-06 0.28
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 1.293e-06 0.32
PTN7_HUMAN PTPN7 Tyrosine-protein phosphatase non-receptor type 7 1.333e-06 0.35
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 1.369e-06 0.29
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 1.385e-06 0.30
LDLR_HUMAN LDLR Low-density lipoprotein receptor 1.385e-06 0.30
PLEC_HUMAN PLEC Plectin 1.447e-06 0.36
F13A_HUMAN F13A1 Coagulation factor XIII A chain 1.502e-06 0.38
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.577e-06 0.31
PRIO_MESAU PRNP Major prion protein 1.657e-06 0.30
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 1.906e-06 0.30
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 1.958e-06 0.38
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 2.286e-06 0.39
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 2.528e-06 0.32
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 2.613e-06 0.40
CBPA1_BOVIN CPA1 Carboxypeptidase A1 2.752e-06 0.37
Q9V396_DROME CAH1 Carbonic anhydrase 1 2.768e-06 0.40
Q9VTU8_DROME CAH2 Carbonic anhydrase 2, isoform A 2.768e-06 0.40
C3SLB7_ECOLX glmU Bifunctional protein GlmU 3.559e-06 0.29
GLI1_MOUSE Gli1 Zinc finger protein GLI1 3.718e-06 0.52
Q7ZJM1_9HIV1 pol Integrase 3.913e-06 0.35
GPR55_HUMAN GPR55 G-protein coupled receptor 55 5.358e-06 0.42
V1AR_RAT Avpr1a Vasopressin V1a receptor 5.928e-06 0.33
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 7.112e-06 0.29
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 7.497e-06 0.38
FACE2_HUMAN RCE1 CAAX prenyl protease 2 8.06e-06 0.33
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 8.09e-06 0.28
MMP12_HUMAN MMP12 Macrophage metalloelastase 8.24e-06 0.38
LYAM2_HUMAN SELE E-selectin 8.488e-06 0.36
KLF5_HUMAN KLF5 Krueppel-like factor 5 8.631e-06 0.35
MMP2_HUMAN MMP2 72 kDa type IV collagenase 9.034e-06 0.41
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 9.085e-06 0.33
PDGFB_HUMAN PDGFB Platelet-derived growth factor subunit B 9.582e-06 0.30

Sofpironium

AMYP_RAT Amy2 Pancreatic alpha-amylase 4.79e-63 0.37
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 8.421e-43 0.69
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 9.141e-43 0.45
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 1.291e-40 0.45
GSTT1_RAT Gstt1 Glutathione S-transferase theta-1 6.694e-38 0.30
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 6.234e-34 0.69
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 4.133e-30 0.69
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 3.119e-28 0.45
Q8WMX0_BOVIN Muscarinic receptor M1 1.11e-16 0.29
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 5.551e-16 0.30
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 4.774e-15 0.33
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.543e-14 0.69
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.338e-12 0.69
MEN1_HUMAN MEN1 Menin 1.701e-07 0.29
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 2.76e-07 0.36
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 3.716e-06 0.30

Azaribine

Q8T6J6_PLAFA ompdc Orotidine 5'-monophosphate decarboxylase 1.414e-62 0.50
PYRF_YEAST URA3 Orotidine 5'-phosphate decarboxylase 3.686e-51 0.51
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.964e-38 0.44
P2RY2_RAT P2ry2 P2Y purinoceptor 2 1.215e-35 0.28
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.794e-31 0.45
CAH9_HUMAN CA9 Carbonic anhydrase 9 1.613e-29 0.45
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 2.755e-27 0.32
PUR6_CHICK AIRC Multifunctional protein ADE2 1.223e-26 0.31
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.686e-23 0.45
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 1.768e-23 0.30
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 1.891e-23 0.32
TYSY_BOVIN TYMS Thymidylate synthase 4.185e-23 0.28
CAH2_HUMAN CA2 Carbonic anhydrase 2 7.106e-21 0.45
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 5.41e-19 0.30
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 4.473e-18 0.33
P2RY4_RAT P2ry4 P2Y purinoceptor 4 8.52e-18 0.28
KITH_RAT Tk1 Thymidine kinase, cytosolic 9.056e-18 0.28
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 2.22e-16 0.31
AMY1A_HUMAN AMY1A Alpha-amylase 1 6.661e-16 0.30
Q194T1_9INFA Neuraminidase 6.661e-16 0.30
CD69_HUMAN CD69 Early activation antigen CD69 3.619e-14 0.35
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 3.619e-14 0.35
P2RY6_RAT P2ry6 P2Y purinoceptor 6 2.601e-13 0.29
PYRF_METTH pyrF Orotidine 5'-phosphate decarboxylase 8.444e-13 0.31
P2RY2_MOUSE P2ry2 P2Y purinoceptor 2 1.383e-11 0.28
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 9.455e-11 0.29
KITH_VZVD TK Thymidine kinase 3.866e-10 0.29
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 6.704e-09 0.32
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.045e-06 0.40
CAH13_HUMAN CA13 Carbonic anhydrase 13 1.156e-06 0.40
GRIK5_HUMAN GRIK5 Glutamate receptor ionotropic, kainate 5 1.239e-06 0.34
CAH6_HUMAN CA6 Carbonic anhydrase 6 1.709e-06 0.40
OGT1_HUMAN OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 3.847e-06 0.29

NITHIAMIDE

PK3CG_MOUSE Pik3cg Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 3.241e-51 0.33
CAH7_MOUSE Ca7 Carbonic anhydrase 7 5.965e-45 0.36
CAHX_FLABI Carbonic anhydrase 5.965e-45 0.36
OGA_RAT Oga Protein O-GlcNAcase 1.766e-44 0.35
Q9X9I8_YEREN irp9 Salicylate synthetase, Irp9 3.917e-38 0.30
UBP47_HUMAN USP47 Ubiquitin carboxyl-terminal hydrolase 47 5.836e-37 0.33
TESK2_HUMAN TESK2 Dual specificity testis-specific protein kinase 2 9.775e-24 0.31
MYOC_HUMAN MYOC Myocilin 1.605e-23 0.29
FFAR2_HUMAN FFAR2 Free fatty acid receptor 2 3.132e-23 0.32
Q9HVB9_PSEAE Carbonic anhydrase 2.457e-22 0.36
UBP7_HUMAN USP7 Ubiquitin carboxyl-terminal hydrolase 7 5.091e-20 0.31
HXK4_RAT Gck Hexokinase-4 1.11e-16 0.29
SENP8_HUMAN SENP8 Sentrin-specific protease 8 4.508e-14 0.36
GSK3B_MOUSE Gsk3b Glycogen synthase kinase-3 beta 6.162e-14 0.54
Q2PCB5_DICLA ca Carbonic anhydrase 3.741e-13 0.36
CASP6_HUMAN CASP6 Caspase-6 1.127e-12 0.54
SENP6_HUMAN SENP6 Sentrin-specific protease 6 6.107e-12 0.36
H6TY12_PERAM Nicotinic acetylcholine receptor alpha8 subunit 1.332e-11 0.29
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5.563e-10 0.36
PK3CB_RAT Pik3cb Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 2.039e-09 0.29
CAH11_HUMAN CA11 Carbonic anhydrase-related protein 11 1.319e-08 0.36
MITF_HUMAN MITF Microphthalmia-associated transcription factor 2.395e-08 0.37
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 6.142e-08 0.53
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 1.417e-07 0.54
GALR2_HUMAN GALR2 Galanin receptor type 2 1.442e-07 0.32
CAH_METTE Carbonic anhydrase 3.68e-07 0.36
GYRB_MYCS2 gyrB DNA gyrase subunit B 8.358e-07 0.29
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 3.78e-06 0.31
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 4.431e-06 0.36
SENP7_HUMAN SENP7 Sentrin-specific protease 7 5.422e-06 0.33
OGA_HUMAN OGA Protein O-GlcNAcase 5.601e-06 0.35
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 8.779e-06 0.34
ACH4_DROME nAChRbeta2 Acetylcholine receptor subunit beta-like 2 9.511e-06 0.29

Acetomenaphthone

NCEH1_HUMAN NCEH1 Neutral cholesterol ester hydrolase 1 2.033e-48 0.34
CFAD_RAT Cfd Complement factor D 5.965e-45 0.36
A6H249_FLAPJ pop Prolyl oligopeptidase family protein 4.673e-41 0.33
TLR1_MOUSE Tlr1 Toll-like receptor 1 1.409e-27 0.45
TLR2_MOUSE Tlr2 Toll-like receptor 2 1.409e-27 0.45
POLG_HRV16 Genome polyprotein 3.335e-27 0.33
KCNB1_HUMAN KCNB1 Potassium voltage-gated channel subfamily B member 1 2.847e-23 0.29
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 3.334e-18 0.29
MCR_RAT Nr3c2 Mineralocorticoid receptor 5.855e-18 0.29
K4JQ36_LAOST ace2 Carboxylic ester hydrolase 1.882e-17 0.33
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 2.354e-14 0.35
Q7YWJ9_MUSDO Ache Carboxylic ester hydrolase 2.492e-12 0.33
Q9NJH6_NEPCI AO-AChE Ace-orthologous acetylcholinesterase 2.492e-12 0.33
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 4.782e-11 0.39
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 2.929e-08 0.29
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 2.929e-08 0.29
CEL_BOVIN CEL Bile salt-activated lipase 1.746e-07 0.31
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 3.792e-07 0.32
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 9.233e-07 0.44
Q9BEG3_BOVIN 5-lipoxygenase 1.28e-06 0.39
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 1.788e-06 0.32
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 3.918e-06 0.43

Syrosingopine

VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 9.898e-46 0.85
ADA2A_PIG ADRA2A Alpha-2A adrenergic receptor 5.401e-37 0.46
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 2.989e-33 0.85
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 2.181e-21 0.85
TRPM8_MOUSE Trpm8 Transient receptor potential cation channel subfamily M member 8 2.977e-18 0.34
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 8.837e-14 0.46
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 3.922e-13 0.29
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 2.292e-10 0.46
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 6.8e-10 0.46
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 8.239e-10 0.46
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 7.433e-09 0.85
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 7.624e-09 0.34
NORA_STAAU norA Quinolone resistance protein NorA 9.582e-09 0.85
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 3.12e-08 0.32
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 2.704e-07 0.34
ADA2B_RAT Adra2b Alpha-2B adrenergic receptor 4.617e-07 0.46
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 1.215e-06 0.33
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 5.416e-06 0.46

Chlorothymol

THB_RAT Thrb Thyroid hormone receptor beta 6.852e-44 0.35
THA_HUMAN THRA Thyroid hormone receptor alpha 1.726e-29 0.36
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 3.781e-28 0.45
THB_HUMAN THRB Thyroid hormone receptor beta 4.059e-24 0.36
HST2_YEAST HST2 NAD-dependent protein deacetylase HST2 2.318e-20 0.32
PPO1_AGABI PPO1 Polyphenol oxidase 1 2.791e-09 0.29
Q9BHT9_PLABE G6PD-6PGL Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 5.985e-07 0.39

Sebetralstat

PDPK1_HUMAN PDPK1 3-phosphoinositide-dependent protein kinase 1 1.172e-40 0.39
Q76353_9HIV1 Integrase 5.44e-32 0.35
MMP10_HUMAN MMP10 Stromelysin-2 2.402e-24 0.35
ACOD1_MOUSE Scd1 Acyl-CoA desaturase 1 7.194e-21 0.32
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 7.084e-18 0.32
Q7ZJM1_9HIV1 pol Integrase 1.443e-15 0.35
CYB_PIG MT-CYB Cytochrome b 3.109e-15 0.28
DRD1_BOVIN DRD1 D(1A) dopamine receptor 4.996e-14 0.30
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 2.839e-11 0.28
ACOD_HUMAN SCD Acyl-CoA desaturase 5.518e-11 0.32
KLKB1_HUMAN KLKB1 Plasma kallikrein 1.073e-10 0.40
EGLN1_HUMAN EGLN1 Egl nine homolog 1 1.099e-10 0.30
DPOL_HHV6U U38 DNA polymerase catalytic subunit 2.37e-09 0.33
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 3.761e-09 0.32
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 7.434e-08 0.30
MMP13_HUMAN MMP13 Collagenase 3 1.175e-07 0.38
PDE5A_HUMAN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 6.234e-07 0.32
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 1.267e-06 0.32
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 2.114e-06 0.30
DPOL_HCMVA UL54 DNA polymerase catalytic subunit 2.23e-06 0.30
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 3.905e-06 0.32

Scarlet_red

TCMO_HELTU CYP73A1 Trans-cinnamate 4-monooxygenase 1.921e-39 0.31
PTP1_YEAST PTP1 Tyrosine-protein phosphatase 1 1.198e-30 0.31
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 2.38e-24 0.35
BRD4_MOUSE Brd4 Bromodomain-containing protein 4 6.243e-24 0.29
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 6.859e-22 0.32
TPOR_HUMAN MPL Thrombopoietin receptor 2.106e-21 0.45
VGLU3_RAT Slc17a8 Vesicular glutamate transporter 3 2.576e-18 0.29
TERA_MOUSE Vcp Transitional endoplasmic reticulum ATPase 2.946e-17 0.32
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 3.186e-17 0.40
HIS1_MYCTU hisG ATP phosphoribosyltransferase 1.11e-16 0.37
BPTF_HUMAN BPTF Nucleosome-remodeling factor subunit BPTF 1.665e-15 0.29
ATP4B_PIG ATP4B Potassium-transporting ATPase subunit beta 5.371e-10 0.28
Q8IL32_PLAF7 Heat shock protein 90, putative 5.374e-10 0.58
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 1.379e-09 0.36
Q49PX0_9POXV N1L N1L 7.576e-09 0.31
PTPRA_HUMAN PTPRA Receptor-type tyrosine-protein phosphatase alpha 1.649e-08 0.49
KLF5_HUMAN KLF5 Krueppel-like factor 5 2.088e-07 0.34
CEL_BOVIN CEL Bile salt-activated lipase 3.884e-07 0.29
SMCA4_HUMAN SMARCA4 Transcription activator BRG1 6.257e-07 0.29
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 9.486e-07 0.39
STRP_STRP1 ska Streptokinase A 1.297e-06 0.47
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 1.489e-06 0.38
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.558e-06 0.29
ATP4A_PIG ATP4A Potassium-transporting ATPase alpha chain 1 3.293e-06 0.28
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 3.496e-06 0.34
LMP1_EBVB9 LMP1 Latent membrane protein 1 5.893e-06 0.46
TCMO_POPKI CYP73A16 Trans-cinnamate 4-monooxygenase 7.884e-06 0.31

Methylhexaneamine

Q29571_PIG Leucine aminopeptidase 7.142e-37 0.29
AMPB_RAT Rnpep Aminopeptidase B 1.404e-13 0.29

OCTODRINE

Q29571_PIG Leucine aminopeptidase 7.142e-37 0.29
AMPB_RAT Rnpep Aminopeptidase B 1.404e-13 0.29
DCOR_RAT Odc1 Ornithine decarboxylase 2.055e-09 0.38
LSS_RAT Lss Lanosterol synthase 1.237e-06 0.33

Deuruxolitinib

JAK3_RAT Jak3 Tyrosine-protein kinase JAK3 1.457e-36 0.29
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 5.517e-31 0.70
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 5.197e-25 0.70
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 2.505e-21 0.70
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 1.908e-18 0.70
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 8.706e-18 0.70
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 8.706e-18 0.70
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 8.706e-18 0.70
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 8.706e-18 0.70
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 1.11e-16 0.70
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 3.331e-16 0.70
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 3.331e-16 0.70
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 3.331e-16 0.70
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 5.551e-16 0.70
DMPK_HUMAN DMPK Myotonin-protein kinase 1.332e-15 0.70
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1.887e-15 0.70
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 7.438e-15 0.70
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 2.709e-14 0.70
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 2.709e-14 0.70
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 3.353e-14 0.70
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 8.593e-14 0.70
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 8.593e-14 0.70
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 1.283e-13 0.70
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 1.283e-13 0.70
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 4.292e-13 0.70
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 5.683e-13 0.70
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 3.603e-12 0.70
PAK5_HUMAN PAK5 Serine/threonine-protein kinase PAK 5 3.603e-12 0.70
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 7.163e-12 0.29
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 7.739e-12 0.70
KCC1D_HUMAN CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 1.044e-11 0.70
RIOK1_HUMAN RIOK1 Serine/threonine-protein kinase RIO1 1.577e-11 0.70
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 1.577e-11 0.70
RIOK3_HUMAN RIOK3 Serine/threonine-protein kinase RIO3 1.577e-11 0.70
BMPR2_HUMAN BMPR2 Bone morphogenetic protein receptor type-2 3.066e-11 0.70
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 3.066e-11 0.70
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 5.713e-11 0.70
GRK4_HUMAN GRK4 G protein-coupled receptor kinase 4 5.713e-11 0.70
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 1.025e-10 0.70
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 1.776e-10 0.70
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 1.776e-10 0.70
ULK2_HUMAN ULK2 Serine/threonine-protein kinase ULK2 1.776e-10 0.70
TPX2_HUMAN TPX2 Targeting protein for Xklp2 2.131e-10 0.30
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 2.984e-10 0.70
MP2K4_HUMAN MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 2.984e-10 0.70
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 5.866e-10 0.29
DAPK2_HUMAN DAPK2 Death-associated protein kinase 2 7.751e-10 0.70
TAOK2_HUMAN TAOK2 Serine/threonine-protein kinase TAO2 7.751e-10 0.70
STK16_HUMAN STK16 Serine/threonine-protein kinase 16 1.204e-09 0.70
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 1.829e-09 0.70
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 2.669e-09 0.70
HIPK3_HUMAN HIPK3 Homeodomain-interacting protein kinase 3 2.724e-09 0.70
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 2.724e-09 0.70
STK26_HUMAN STK26 Serine/threonine-protein kinase 26 2.724e-09 0.70
JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 3.348e-09 0.70
BMR1B_HUMAN BMPR1B Bone morphogenetic protein receptor type-1B 1.125e-08 0.70
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 1.232e-08 0.70
HIPK1_HUMAN HIPK1 Homeodomain-interacting protein kinase 1 2.094e-08 0.70
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 3.491e-08 0.70
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 3.491e-08 0.70
AAK1_HUMAN AAK1 AP2-associated protein kinase 1 4.863e-08 0.70
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 4.863e-08 0.70
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 2.027e-07 0.70
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 3.068e-07 0.70
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 6.254e-07 0.70
KCC1A_HUMAN CAMK1 Calcium/calmodulin-dependent protein kinase type 1 6.668e-07 0.70
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 1.086e-06 0.70
GRK5_HUMAN GRK5 G protein-coupled receptor kinase 5 1.272e-06 0.70
KS6A1_HUMAN RPS6KA1 Ribosomal protein S6 kinase alpha-1 1.356e-06 0.70
SYTC_HUMAN TARS1 Threonine--tRNA ligase 1, cytoplasmic 3.933e-06 0.30
SYT_YERPE thrS Threonine--tRNA ligase 3.933e-06 0.30

Elinzanetant

NK1R_HUMAN TACR1 Substance-P receptor 2.193e-36 0.71
NK3R_HUMAN TACR3 Neuromedin-K receptor 1.42e-30 0.71
IP3KB_HUMAN ITPKB Inositol-trisphosphate 3-kinase B 6.494e-10 0.30
B2RXC2_MOUSE Itpkb Kinase 3.178e-06 0.30

Benzgalantamine

ACES_TETCF ache Acetylcholinesterase 3.185e-35 0.67
OPRX_CAVPO OPRL1 Nociceptin receptor 9.149e-27 0.36
Q9JKC1_RAT Bche Carboxylic ester hydrolase 1.267e-26 0.67
ACES_RAT Ache Acetylcholinesterase 2.605e-24 0.67
OPRM_HUMAN OPRM1 Mu-type opioid receptor 6.432e-21 0.39
OPRM_BOVIN OPRM1 Mu-type opioid receptor 1.725e-18 0.32
Q8WSF8_APLCA Soluble acetylcholine receptor 1.013e-17 0.32
OPRD_HUMAN OPRD1 Delta-type opioid receptor 4.724e-17 0.39
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.11e-16 0.39
OPRM_MOUSE Oprm1 Mu-type opioid receptor 1.859e-11 0.38
HCN1_HUMAN HCN1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 5.523e-11 0.30
HCN4_HUMAN HCN4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 2.346e-10 0.30
SC6A3_BOVIN SLC6A3 Sodium-dependent dopamine transporter 3.866e-10 0.29
ACHP_LYMST Acetylcholine-binding protein 8.999e-10 0.32
OPRD_RAT Oprd1 Delta-type opioid receptor 1.34e-07 0.36
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 1.568e-07 0.29
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 1.67e-07 0.34
OPRM_CAVPO OPRM1 Mu-type opioid receptor 2.022e-07 0.36
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 3.085e-07 0.29
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 1.629e-06 0.34
CYSK_MYCTU cysK1 O-acetylserine sulfhydrylase 1.683e-06 0.29
OX1R_HUMAN HCRTR1 Orexin receptor type 1 2.294e-06 0.35
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 3.31e-06 0.28
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 5.001e-06 0.31
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 6.947e-06 0.30

Suzetrigine

BACE2_HUMAN BACE2 Beta-secretase 2 5.951e-30 0.33
BACE1_HUMAN BACE1 Beta-secretase 1 8.07e-27 0.38
BACE1_MOUSE Bace1 Beta-secretase 1 9.126e-12 0.30
BACE2_RAT Bace2 Beta-secretase 2 4.981e-09 0.28
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 3.793e-07 0.34

Aminometradine

AA2AR_CAVPO ADORA2A Adenosine receptor A2a 7.038e-25 0.41
AA2BR_RAT Adora2b Adenosine receptor A2b 1.149e-06 0.29
EF2K_HUMAN EEF2K Eukaryotic elongation factor 2 kinase 5.923e-06 0.32

Sevabertinib

GPR84_HUMAN GPR84 G-protein coupled receptor 84 1.767e-21 0.36
MAPK2_HUMAN MAPKAPK2 MAP kinase-activated protein kinase 2 1.656e-06 0.31

Revumenib

O70424_RAT Neuropeptide Y-Y2 receptor 9.771e-18 0.28
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 1.998e-15 0.32
PI3R5_HUMAN PIK3R5 Phosphoinositide 3-kinase regulatory subunit 5 1.219e-10 0.28
CRFR2_HUMAN CRHR2 Corticotropin-releasing factor receptor 2 8.647e-10 0.31
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 3.855e-06 0.28

Iopydone

DPYD_HUMAN DPYD Dihydropyrimidine dehydrogenase [NADP(+)] 1.399e-14 0.36

Taletrectinib

GALR2_RAT Galr2 Galanin receptor type 2 1.104e-09 0.28

Amisometradine

FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 9.511e-06 0.29