Results of Job: search_cd0630ef-dcf5-497b-9c05-3d8276246ece

Query Target Key Target Name Description P-Value MaxTC

ZINC507587463

KPYR_HUMAN PKLR Pyruvate kinase PKLR 1.77e-294 0.52
S40A1_HUMAN SLC40A1 Solute carrier family 40 member 1 2.724e-132 0.50
C0L093_TOBAC Acetolactate synthase 9.012e-68 0.38
SGK1_HUMAN SGK1 Serine/threonine-protein kinase Sgk1 3.744e-66 0.38
IKBA_HUMAN NFKBIA NF-kappa-B inhibitor alpha 3.971e-65 0.42
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 1.323e-50 0.49
DHB1_RAT Hsd17b1 Estradiol 17-beta-dehydrogenase 1 1.552e-50 0.33
DHB2_RAT Hsd17b2 Estradiol 17-beta-dehydrogenase 2 1.552e-50 0.33
CCR4_CANLF CCR4 C-C chemokine receptor type 4 2.471e-46 0.30
NMDZ1_MOUSE Grin1 Glutamate receptor ionotropic, NMDA 1 3.875e-36 0.29
S20A2_HUMAN SLC20A2 Sodium-dependent phosphate transporter 2 3.875e-36 0.29
BCAT1_RAT Bcat1 Branched-chain-amino-acid aminotransferase, cytosolic 1.215e-35 0.28
BCAT2_RAT Bcat2 Branched-chain-amino-acid aminotransferase, mitochondrial 1.215e-35 0.28
A6QR73_RAT Gpr39 G protein-coupled receptor 39 2.141e-35 0.32
ARAF_HUMAN ARAF Serine/threonine-protein kinase A-Raf 3.152e-34 0.32
A3KMY8_BOVIN GUSB Beta-glucuronidase 5.311e-34 0.45
PPBT_HUMAN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 3.18e-32 0.40
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 3.649e-32 0.37
TF65_HUMAN RELA Transcription factor p65 3.303e-31 0.42
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 9.332e-28 0.49
PDE4C_HUMAN PDE4C cAMP-specific 3',5'-cyclic phosphodiesterase 4C 1.323e-27 0.35
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 2.011e-26 0.44
CCR9_HUMAN CCR9 C-C chemokine receptor type 9 3.509e-25 0.33
MOGT2_MOUSE Mogat2 2-acylglycerol O-acyltransferase 2 9.719e-24 0.29
S20A1_HUMAN SLC20A1 Sodium-dependent phosphate transporter 1 2.847e-23 0.29
MECP2_HUMAN MECP2 Methyl-CpG-binding protein 2 1.51e-22 0.36
DHB1_MOUSE Hsd17b1 Estradiol 17-beta-dehydrogenase 1 6.654e-21 0.33
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 1.597e-20 0.35
GLRA3_HUMAN GLRA3 Glycine receptor subunit alpha-3 9.359e-19 0.34
DHB2_MOUSE Hsd17b2 Estradiol 17-beta-dehydrogenase 2 1.882e-17 0.33
QCR7_HUMAN UQCRB Cytochrome b-c1 complex subunit 7 8.882e-16 0.30
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.11e-15 0.40
NR1I2_HUMAN NR1I2 Nuclear receptor subfamily 1 group I member 2 1.332e-15 0.35
F264_HUMAN PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 1.443e-15 0.30
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 2.376e-14 0.34
V5TFZ2_9FLAV Nonstructural protein 5 6.184e-14 0.38
Q548M1_ECOLX groL 60 kDa chaperonin 1.058e-13 0.32
Q7BGE6_ECOLX groES 10 kDa chaperonin 1.058e-13 0.32
AMPX_VIBPR Bacterial leucyl aminopeptidase 2.665e-13 0.33
BCAT1_HUMAN BCAT1 Branched-chain-amino-acid aminotransferase, cytosolic 3.146e-13 0.29
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 3.871e-13 0.40
CCR4_MOUSE Ccr4 C-C chemokine receptor type 4 6.217e-13 0.30
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 7.688e-13 0.35
LMP1_EBVB9 LMP1 Latent membrane protein 1 8.151e-13 0.34
TYSY_ECOLI thyA Thymidylate synthase 1.153e-12 0.49
EGLN1_HUMAN EGLN1 Egl nine homolog 1 4.488e-12 0.37
PDE4B_RAT Pde4b cAMP-specific 3',5'-cyclic phosphodiesterase 4B 5.197e-12 0.32
Q03732_HBV HBcAg Capsid protein 5.421e-12 0.35
MTNN_ECOLI mtnN 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 9.236e-12 0.34
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 2.413e-11 0.33
KPYM_HUMAN PKM Pyruvate kinase PKM 3.335e-11 0.46
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 1.059e-10 0.34
F263_HUMAN PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 1.519e-10 0.40
TRPM5_HUMAN TRPM5 Transient receptor potential cation channel subfamily M member 5 2.429e-10 0.30
BXA1_CLOBO botA Botulinum neurotoxin type A 4.766e-10 0.43
P3C2B_HUMAN PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 2.412e-09 0.34
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 2.44e-09 0.31
PDE4A_HUMAN PDE4A cAMP-specific 3',5'-cyclic phosphodiesterase 4A 2.484e-09 0.35
FACE2_HUMAN RCE1 CAAX prenyl protease 2 2.666e-09 0.31
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 7.351e-09 0.34
STXA_SHIDY stxA Shiga toxin subunit A 1.896e-08 0.30
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 3.02e-08 0.51
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 4.184e-08 0.49
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 4.462e-08 0.35
GPR39_HUMAN GPR39 G-protein coupled receptor 39 5.818e-08 0.32
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 7.138e-08 0.44
INSR_MOUSE Insr Insulin receptor 9.132e-08 0.29
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 1.188e-07 0.34
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 2.6e-07 0.33
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 2.701e-07 0.31
PCKGC_HUMAN PCK1 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] 6.335e-07 0.37
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 7.852e-07 0.36
ACLY_HUMAN ACLY ATP-citrate synthase 9.842e-07 0.30
POLG_DEN2P Genome polyprotein 1.042e-06 0.28
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 1.138e-06 0.31
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 1.435e-06 0.32
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 1.62e-06 0.43
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 2.32e-06 0.29
Q76353_9HIV1 Integrase 2.621e-06 0.33
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 3.025e-06 0.30
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 3.133e-06 0.28
COLA_CLOPE colA Collagenase ColA 4.694e-06 0.33
PK3C3_HUMAN PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 5.194e-06 0.32
SCAF_HCMVA UL80 Capsid scaffolding protein 5.564e-06 0.32
EDNRA_RAT Ednra Endothelin-1 receptor 5.698e-06 0.37
STABP_HUMAN STAMBP STAM-binding protein 8.827e-06 0.29
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 9.769e-06 0.46

ZINC114340891

PEBB_HUMAN CBFB Core-binding factor subunit beta 3.652e-164 0.55
C3SLB7_ECOLX glmU Bifunctional protein GlmU 7.565e-83 0.40
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 1.331e-80 0.47
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 8.76e-80 0.40
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 4.918e-54 0.40
PRIO_SHEEP PRNP Major prion protein 1.149e-51 0.36
SHH_MOUSE Shh Sonic hedgehog protein 4.829e-51 0.46
ENL_HUMAN MLLT1 Protein ENL 9.569e-51 0.32
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 2.488e-49 0.50
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 9.055e-48 0.42
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 6.065e-42 0.33
CSK2A_SCHPO cka1 Casein kinase II subunit alpha 2.281e-40 0.32
GYRA_STAAU gyrA DNA gyrase subunit A 2.886e-39 0.36
HPSE_HUMAN HPSE Heparanase 3.926e-37 0.40
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 1.127e-35 0.29
GRM5_MOUSE Grm5 Metabotropic glutamate receptor 5 2.489e-34 0.34
MAP1_ECOLI map Methionine aminopeptidase 3.46e-33 0.58
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 6.412e-33 0.32
CTNB1_HUMAN CTNNB1 Catenin beta-1 2.328e-30 0.32
NRAM2_HUMAN SLC11A2 Natural resistance-associated macrophage protein 2 6.281e-27 0.30
GRB7_HUMAN GRB7 Growth factor receptor-bound protein 7 1.877e-25 0.29
A6QR73_RAT Gpr39 G protein-coupled receptor 39 4.147e-25 0.32
GYRB_STAAU gyrB DNA gyrase subunit B 1.905e-24 0.36
FTSZ_MYCTU ftsZ Cell division protein FtsZ 2.728e-24 0.30
TSSK3_HUMAN TSSK3 Testis-specific serine/threonine-protein kinase 3 5.448e-24 0.29
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 9.729e-24 0.33
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 3.374e-21 0.34
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 5.747e-21 0.34
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 2.07e-20 0.32
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 4.475e-19 0.51
LDLR_HUMAN LDLR Low-density lipoprotein receptor 6.121e-19 0.32
Q9BJF5_TOXGO CDPK1 Calmodulin-domain protein kinase 1 2.504e-18 0.35
PA_I34A1 PA Polymerase acidic protein 4.077e-18 0.38
AOFB_RAT Maob Amine oxidase [flavin-containing] B 5.739e-18 0.38
ACOD1_RAT Scd1 Acyl-CoA desaturase 1 1.427e-17 0.37
HXK4_HUMAN GCK Hexokinase-4 1.928e-17 0.37
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 1.11e-16 0.43
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 1.11e-16 0.34
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 1.11e-16 0.52
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 1.11e-16 0.34
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 6.661e-16 0.51
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 7.772e-16 0.32
HSP12_CAEEL hsp-16.2 Heat shock protein Hsp-16.2 1.776e-15 0.46
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 2.22e-15 0.36
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 1.588e-14 0.31
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 3.364e-14 0.42
KCNQ2_RAT Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 3.841e-14 0.31
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 3.129e-13 0.35
MAPK2_HUMAN MAPKAPK2 MAP kinase-activated protein kinase 2 4.353e-13 0.35
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 5.533e-13 0.35
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 6.769e-13 0.36
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 8.503e-13 0.35
ANDR_MOUSE Ar Androgen receptor 1.1e-12 0.34
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 6.009e-12 0.29
CXCR2_HUMAN CXCR2 C-X-C chemokine receptor type 2 8.742e-12 0.35
REST_BORBU resT Telomere resolvase ResT 1.437e-11 0.28
KLF5_HUMAN KLF5 Krueppel-like factor 5 2.07e-11 0.35
LUCI_PHOPY Luciferin 4-monooxygenase 2.65e-11 0.42
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 3.296e-11 0.33
TGFR1_HUMAN TGFBR1 TGF-beta receptor type-1 3.868e-11 0.34
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 5.539e-11 0.40
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 6.126e-11 0.36
KLK_PIG Glandular kallikrein 7.829e-11 0.29
INCE_HUMAN INCENP Inner centromere protein 7.922e-11 0.29
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 1.522e-10 0.28
UROK_HUMAN PLAU Urokinase-type plasminogen activator 1.754e-10 0.37
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 2.337e-10 0.43
GPR39_MOUSE Gpr39 G-protein coupled receptor 39 4.123e-10 0.32
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 4.912e-10 0.35
AURKB_HUMAN AURKB Aurora kinase B 6.538e-10 0.40
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 7.859e-10 0.47
SKN1_CAEEL skn-1 Protein skinhead-1 1.187e-09 0.46
FA7_HUMAN F7 Coagulation factor VII 2.229e-09 0.47
TPA_HUMAN PLAT Tissue-type plasminogen activator 3.239e-09 0.30
SENP7_HUMAN SENP7 Sentrin-specific protease 7 4.179e-09 0.38
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 6.537e-09 0.30
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 6.626e-09 0.41
AURKA_HUMAN AURKA Aurora kinase A 1.083e-08 0.38
VGFR2_MOUSE Kdr Vascular endothelial growth factor receptor 2 1.284e-08 0.35
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.349e-08 0.33
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 1.406e-08 0.36
SMO_MOUSE Smo Smoothened homolog 1.437e-08 0.39
GRM7_RAT Grm7 Metabotropic glutamate receptor 7 1.559e-08 0.33
SMO_HUMAN SMO Smoothened homolog 2.421e-08 0.37
GPR39_HUMAN GPR39 G-protein coupled receptor 39 2.929e-08 0.32
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 3.82e-08 0.32
IL6_HUMAN IL6 Interleukin-6 3.935e-08 0.32
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 4.468e-08 0.28
TIE2_HUMAN TEK Angiopoietin-1 receptor 4.808e-08 0.30
PLMN_HUMAN PLG Plasminogen 5.033e-08 0.32
EST1_HUMAN CES1 Liver carboxylesterase 1 1.013e-07 0.41
PDE4C_HUMAN PDE4C cAMP-specific 3',5'-cyclic phosphodiesterase 4C 1.301e-07 0.29
KLK7_HUMAN KLK7 Kallikrein-7 1.398e-07 0.41
SL9A1_RAT Slc9a1 Sodium/hydrogen exchanger 1 1.901e-07 0.33
SHH_HUMAN SHH Sonic hedgehog protein 2.284e-07 0.33
EXSA_PSEAE exsA Exoenzyme S synthesis regulatory protein ExsA 2.362e-07 0.29
NPY5R_MOUSE Npy5r Neuropeptide Y receptor type 5 2.681e-07 0.34
O97467_PLAFA ht1 Hexose transporter 1 2.874e-07 0.33
O61059_LEIME LmGT2 Glucose transporter 3.231e-07 0.33
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 3.923e-07 0.29
AA3R_HUMAN ADORA3 Adenosine receptor A3 4.389e-07 0.39
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 5.332e-07 0.32
SMCA4_HUMAN SMARCA4 Transcription activator BRG1 5.475e-07 0.30
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 6.847e-07 0.41
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 6.928e-07 0.43
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 7.053e-07 0.45
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 1.017e-06 0.31
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 1.247e-06 0.32
MAP11_HUMAN METAP1 Methionine aminopeptidase 1 1.247e-06 0.31
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.367e-06 0.36
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 1.391e-06 0.33
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 1.474e-06 0.40
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.808e-06 0.33
TOP1_HUMAN TOP1 DNA topoisomerase 1 2.215e-06 0.33
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 2.223e-06 0.30
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 2.325e-06 0.34
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 3.124e-06 0.31
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 3.654e-06 0.32
GBRA5_HUMAN GABRA5 Gamma-aminobutyric acid receptor subunit alpha-5 4.155e-06 0.31
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 4.764e-06 0.32
TRYP_PIG Trypsin 5.031e-06 0.36
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 5.262e-06 0.32
PDPK1_HUMAN PDPK1 3-phosphoinositide-dependent protein kinase 1 5.829e-06 0.46
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 6.237e-06 0.32
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 7.355e-06 0.29
ACOD_HUMAN SCD Acyl-CoA desaturase 8.026e-06 0.34
DUS6_RAT Dusp6 Dual specificity protein phosphatase 6 9.884e-06 0.39

ZINC1644023376

SYUA_HUMAN SNCA Alpha-synuclein 2.888e-119 0.42
CATL2_HUMAN CTSV Cathepsin L2 1.205e-41 0.41
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 6.289e-38 0.33
FOLB_STAAU folB Dihydroneopterin aldolase 8.297e-37 0.29
NPT2C_HUMAN SLC34A3 Sodium-dependent phosphate transport protein 2C 9.406e-37 0.29
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 1.458e-32 0.46
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 4.559e-32 0.42
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 1.684e-31 0.37
MEP50_HUMAN WDR77 Methylosome protein 50 1.485e-25 0.35
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 2.694e-25 0.35
ITA2B_MOUSE Itga2b Integrin alpha-IIb 2.158e-24 0.30
ITAV_MOUSE Itgav Integrin alpha-V 2.158e-24 0.30
ITB3_MOUSE Itgb3 Integrin beta-3 2.158e-24 0.30
S20A1_HUMAN SLC20A1 Sodium-dependent phosphate transporter 1 1.158e-23 0.29
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 5.651e-22 0.32
GIPR_RAT Gipr Gastric inhibitory polypeptide receptor 3.429e-19 0.30
NPT2A_HUMAN SLC34A1 Sodium-dependent phosphate transport protein 2A 2.446e-18 0.29
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.07e-17 0.29
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 5.551e-16 0.35
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 2.554e-15 0.34
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 8.993e-15 0.39
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 3.286e-14 0.33
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 9.269e-13 0.33
PDS_SYNE7 pds 15-cis-phytoene desaturase 2.169e-12 0.30
MBTP1_HUMAN MBTPS1 Membrane-bound transcription factor site-1 protease 9.767e-12 0.32
PLD1_HUMAN PLD1 Phospholipase D1 9.827e-12 0.34
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 4.421e-11 0.32
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 5.491e-11 0.35
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 8.572e-11 0.35
CATL1_HUMAN CTSL Cathepsin L1 1.499e-10 0.41
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 5.725e-10 0.32
PLD2_HUMAN PLD2 Phospholipase D2 5.759e-10 0.34
CATB_HUMAN CTSB Cathepsin B 7.744e-10 0.41
UREA_CANEN Urease 1.021e-09 0.29
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 1.67e-09 0.30
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 2.039e-09 0.29
GIPR_HUMAN GIPR Gastric inhibitory polypeptide receptor 3.438e-09 0.35
AOFB_RAT Maob Amine oxidase [flavin-containing] B 1.053e-08 0.45
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 1.234e-08 0.36
GLI1_HUMAN GLI1 Zinc finger protein GLI1 1.462e-08 0.30
DPOL_HHV6U U38 DNA polymerase catalytic subunit 3.505e-08 0.29
CATS_HUMAN CTSS Cathepsin S 4.253e-08 0.41
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 5.455e-08 0.39
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 5.59e-08 0.40
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 5.664e-08 0.40
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 5.739e-08 0.33
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 6.381e-08 0.31
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 6.405e-08 0.38
ITB2_HUMAN ITGB2 Integrin beta-2 6.781e-08 0.31
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 8.868e-08 0.29
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 1.638e-07 0.29
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 1.815e-07 0.40
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 2.187e-07 0.36
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 2.571e-07 0.31
O61059_LEIME LmGT2 Glucose transporter 2.65e-07 0.33
Q8MTZ4_9TRYP PPase1 Vacuolar-type proton translocating pyrophosphatase 1 2.853e-07 0.31
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 3.012e-07 0.31
CATK_HUMAN CTSK Cathepsin K 5.014e-07 0.41
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 5.806e-07 0.37
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 6.46e-07 0.29
ITAL_HUMAN ITGAL Integrin alpha-L 1.02e-06 0.31
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 1.342e-06 0.38
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 1.505e-06 0.35
PRIO_SHEEP PRNP Major prion protein 1.507e-06 0.30
O97467_PLAFA ht1 Hexose transporter 1 1.641e-06 0.33
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 1.861e-06 0.30
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 1.913e-06 0.30
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 2.293e-06 0.35
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.515e-06 0.30
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 3.317e-06 0.42
MC5R_HUMAN MC5R Melanocortin receptor 5 3.357e-06 0.34
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 3.534e-06 0.33
AMPD2_HUMAN AMPD2 AMP deaminase 2 3.597e-06 0.28
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 3.994e-06 0.33
MAP2_HUMAN METAP2 Methionine aminopeptidase 2 6.906e-06 0.35
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 8.017e-06 0.38
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 9.549e-06 0.42

ZINC1602379535

RXFP1_HUMAN RXFP1 Relaxin receptor 1 7.693e-118 0.35
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 7.808e-84 0.39
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 6.916e-70 0.36
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 4.332e-67 0.34
SORT_HUMAN SORT1 Sortilin 6.916e-54 0.36
BXE_CLOBO botE Botulinum neurotoxin type E 3.553e-48 0.33
TRPV1_CAVPO Trpv1 Transient receptor potential cation channel subfamily V member 1 4.407e-45 0.36
Q25615_ONCVO Chitinase 6.509e-42 0.35
SHH_MOUSE Shh Sonic hedgehog protein 6.606e-42 0.34
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.711e-40 0.45
RXFP2_HUMAN RXFP2 Relaxin receptor 2 2.135e-40 0.35
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 6.05e-39 0.38
BAP1_HUMAN BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1 1.443e-37 0.30
COX1_SHEEP MT-CO1 Cytochrome c oxidase subunit 1 3.56e-37 0.29
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 5.111e-33 0.39
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 4.071e-30 0.36
GRM5_MOUSE Grm5 Metabotropic glutamate receptor 5 1.494e-29 0.29
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 9.327e-28 0.37
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 3.078e-25 0.35
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 7.84e-25 0.35
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 8.117e-25 0.38
PTGES_HUMAN PTGES Prostaglandin E synthase 8.898e-25 0.35
ENL_HUMAN MLLT1 Protein ENL 9.719e-24 0.29
NR1H4_HUMAN NR1H4 Bile acid receptor 4.613e-23 0.37
TMPS4_HUMAN TMPRSS4 Transmembrane protease serine 4 6.377e-23 0.28
CTNB1_HUMAN CTNNB1 Catenin beta-1 6.897e-23 0.38
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 8.818e-21 0.29
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 2.493e-20 0.32
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 2.13e-19 0.37
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 2.786e-19 0.34
PARG_HUMAN PARG Poly(ADP-ribose) glycohydrolase 1.211e-18 0.30
OXDD_HUMAN DDO D-aspartate oxidase 4.879e-18 0.29
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 5.606e-18 0.35
TRPC1_HUMAN TRPC1 Short transient receptor potential channel 1 8.52e-18 0.28
O31272_9GAMM imiS Beta-lactamase 1.928e-17 0.28
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 6.661e-16 0.35
PDE7A_HUMAN PDE7A High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A 9.992e-16 0.34
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 1.776e-15 0.36
MET_HUMAN MET Hepatocyte growth factor receptor 3.997e-15 0.34
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 4.774e-15 0.36
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 5.995e-15 0.34
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 8.105e-15 0.36
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 4.274e-14 0.33
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 5.085e-14 0.33
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 5.573e-14 0.31
WNT3A_MOUSE Wnt3a Protein Wnt-3a 6.017e-14 0.29
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 7.228e-14 0.31
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 7.96e-14 0.31
OPRX_HUMAN OPRL1 Nociceptin receptor 1.369e-13 0.35
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 1.826e-13 0.31
SMO_HUMAN SMO Smoothened homolog 1.947e-12 0.34
PTGES_CANLF PTGES Prostaglandin E synthase 3.405e-12 0.33
AURKB_HUMAN AURKB Aurora kinase B 5.347e-12 0.36
AURKA_HUMAN AURKA Aurora kinase A 5.555e-12 0.38
PRIO_SHEEP PRNP Major prion protein 6.01e-12 0.29
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 6.815e-12 0.37
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 1.011e-11 0.35
Q03732_HBV HBcAg Capsid protein 4.133e-11 0.32
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 7.653e-11 0.33
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 9.455e-11 0.29
RORB_HUMAN RORB Nuclear receptor ROR-beta 9.601e-11 0.30
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 1.248e-10 0.30
BLK_HUMAN BLK Tyrosine-protein kinase Blk 1.413e-10 0.34
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 2.639e-10 0.37
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 5.526e-10 0.36
AOFB_RAT Maob Amine oxidase [flavin-containing] B 6.165e-10 0.36
PYGL_RAT Pygl Glycogen phosphorylase, liver form 6.538e-10 0.29
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 8.972e-10 0.28
ST17A_HUMAN STK17A Serine/threonine-protein kinase 17A 1.124e-09 0.34
Q38C41_TRYB2 Phosphotransferase 1.469e-09 0.31
TERT_HUMAN TERT Telomerase reverse transcriptase 1.673e-09 0.40
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 1.784e-09 0.32
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 2.042e-09 0.37
CH10_HUMAN HSPE1 10 kDa heat shock protein, mitochondrial 2.714e-09 0.31
CH60_HUMAN HSPD1 60 kDa heat shock protein, mitochondrial 2.714e-09 0.31
APOB_HUMAN APOB Apolipoprotein B-100 3.069e-09 0.31
PARP4_HUMAN PARP4 Protein mono-ADP-ribosyltransferase PARP4 3.108e-09 0.29
RORA_HUMAN RORA Nuclear receptor ROR-alpha 4.668e-09 0.30
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 5.565e-09 0.34
PLEC_HUMAN PLEC Plectin 9.277e-09 0.31
STXA_SHIDY stxA Shiga toxin subunit A 1.383e-08 0.30
DYRK3_HUMAN DYRK3 Dual specificity tyrosine-phosphorylation-regulated kinase 3 1.545e-08 0.35
PDE4A_HUMAN PDE4A cAMP-specific 3',5'-cyclic phosphodiesterase 4A 2.681e-08 0.33
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 3.261e-08 0.39
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 3.726e-08 0.39
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 3.91e-08 0.30
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 6.044e-08 0.34
HIPK2_HUMAN HIPK2 Homeodomain-interacting protein kinase 2 8.128e-08 0.34
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 9.586e-08 0.33
RARA_HUMAN RARA Retinoic acid receptor alpha 9.855e-08 0.47
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 1.079e-07 0.35
O68720_YERPE yopH Targeted effector protein 1.213e-07 0.29
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 1.384e-07 0.30
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 1.634e-07 0.34
PAR1_HUMAN F2R Proteinase-activated receptor 1 1.981e-07 0.35
IL6_HUMAN IL6 Interleukin-6 2.362e-07 0.29
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 2.482e-07 0.38
AGTRA_RAT Agtr1 Type-1A angiotensin II receptor 2.761e-07 0.31
TPA_HUMAN PLAT Tissue-type plasminogen activator 2.777e-07 0.38
MARK3_HUMAN MARK3 MAP/microtubule affinity-regulating kinase 3 3.276e-07 0.34
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 3.546e-07 0.34
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 3.563e-07 0.31
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 3.672e-07 0.31
LUCI_PHOPY Luciferin 4-monooxygenase 4.209e-07 0.41
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4.675e-07 0.35
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 5.972e-07 0.30
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 6.098e-07 0.34
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 8.215e-07 0.34
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 9.22e-07 0.39
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 1.018e-06 0.32
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 1.101e-06 0.32
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 1.117e-06 0.35
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 1.137e-06 0.31
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 1.167e-06 0.35
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 1.192e-06 0.31
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 1.25e-06 0.34
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 1.365e-06 0.35
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 1.565e-06 0.34
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 1.893e-06 0.34
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 1.966e-06 0.38
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 1.975e-06 0.31
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 1.984e-06 0.34
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 2.109e-06 0.34
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 2.512e-06 0.31
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 3.295e-06 0.34
KCC2G_HUMAN CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 3.608e-06 0.34
MINK1_HUMAN MINK1 Misshapen-like kinase 1 3.61e-06 0.34
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 3.801e-06 0.30
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 4.27e-06 0.29
LYOX_HUMAN LOX Protein-lysine 6-oxidase 4.687e-06 0.30
PARP2_HUMAN PARP2 Poly [ADP-ribose] polymerase 2 4.736e-06 0.32
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 4.963e-06 0.38
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 5.233e-06 0.34
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 5.567e-06 0.28
SENP7_HUMAN SENP7 Sentrin-specific protease 7 6.814e-06 0.33
FRK_HUMAN FRK Tyrosine-protein kinase FRK 7.221e-06 0.34
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 8.198e-06 0.34
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 8.29e-06 0.34
LUCI_AQULA Luciferin 4-monooxygenase 8.755e-06 0.28
CATD_HUMAN CTSD Cathepsin D 9.53e-06 0.33

ZINC1608784307

SYUA_HUMAN SNCA Alpha-synuclein 5.381e-111 0.49
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 2.278e-76 0.45
ASAH1_HUMAN ASAH1 Acid ceramidase 8.084e-72 0.32
DRD5_RAT Drd5 D(1B) dopamine receptor 4.751e-68 0.31
SENP1_HUMAN SENP1 Sentrin-specific protease 1 5.953e-62 0.36
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 5.943e-57 0.36
CBPC2_HUMAN AGBL2 Cytosolic carboxypeptidase 2 9.185e-54 0.43
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 8.065e-53 0.39
VE1_HPV11 E1 Replication protein E1 4.613e-51 0.37
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.057e-50 0.48
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 1.547e-49 0.41
GPR52_HUMAN GPR52 G-protein coupled receptor 52 1.545e-43 0.32
CRTM_STAAU crtM 4,4'-diapophytoene synthase 3.225e-42 0.37
E2AK3_RAT Eif2ak3 Eukaryotic translation initiation factor 2-alpha kinase 3 2.269e-41 0.33
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 9.337e-41 0.45
SENP2_HUMAN SENP2 Sentrin-specific protease 2 9.519e-41 0.32
PADI6_HUMAN PADI6 Protein-arginine deiminase type-6 6.568e-40 0.35
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 8.181e-40 0.35
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 2.088e-37 0.34
FURIN_HUMAN FURIN Furin 1.126e-36 0.33
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.599e-36 0.43
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 9.258e-35 0.30
AMP1_PLAFQ M1 family aminopeptidase 3.13e-34 0.37
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 3.489e-34 0.44
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 1.936e-33 0.40
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 2.564e-32 0.33
COMT_PIG COMT Catechol O-methyltransferase 4.907e-31 0.38
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 1.893e-30 0.38
POLG_WNV Genome polyprotein 1.609e-29 0.30
LIPL_HUMAN LPL Lipoprotein lipase 1.055e-28 0.46
Q6RY99_RAT Tetraspanin 1.324e-28 0.41
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 2.165e-28 0.36
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 6.417e-28 0.36
A5H660_SCHMA HDAC8 Histone deacetylase 8 7.713e-28 0.38
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 5.172e-27 0.43
HDAC6_HUMAN HDAC6 Histone deacetylase 6 3.311e-25 0.50
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.099e-24 0.39
LYAM1_HUMAN SELL L-selectin 3.314e-24 0.37
ARBK1_HUMAN GRK2 Beta-adrenergic receptor kinase 1 3.946e-24 0.40
NEP_RAT Mme Neprilysin 5.964e-24 0.37
IL8_HUMAN CXCL8 Interleukin-8 6.259e-24 0.40
FABP4_RAT Fabp4 Fatty acid-binding protein, adipocyte 1.239e-23 0.29
AOC2_HUMAN AOC2 Retina-specific copper amine oxidase 1.742e-23 0.30
DRD1_PIG DRD1 D(1A) dopamine receptor 2.704e-23 0.35
PERM_HUMAN MPO Myeloperoxidase 5.039e-23 0.44
DRD3_RAT Drd3 D(3) dopamine receptor 1.609e-22 0.33
AMPN_PIG ANPEP Aminopeptidase N 2.667e-22 0.39
Q25856_PLAFA PFG6PD Glucose-6-phosphate dehydrogenase 5.498e-22 0.32
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 6.199e-21 0.39
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 6.409e-21 0.47
PADI1_HUMAN PADI1 Protein-arginine deiminase type-1 1.361e-20 0.34
PADI3_HUMAN PADI3 Protein-arginine deiminase type-3 1.361e-20 0.34
HDAC8_HUMAN HDAC8 Histone deacetylase 8 2.306e-20 0.50
ACES_MOUSE Ache Acetylcholinesterase 5.007e-20 0.37
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 5.924e-20 0.30
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 1.576e-19 0.35
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 1.859e-19 0.41
TA2R_RAT Tbxa2r Thromboxane A2 receptor 3.406e-19 0.32
Q7ZJM1_9HIV1 pol Integrase 4.73e-19 0.53
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 8.29e-19 0.30
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.066e-17 0.32
NR1H4_HUMAN NR1H4 Bile acid receptor 3.307e-17 0.38
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 1.11e-16 0.30
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.11e-16 0.35
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 1.11e-16 0.34
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 1.11e-16 0.35
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 1.11e-16 0.40
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 2.22e-16 0.39
LYAM3_HUMAN SELP P-selectin 3.331e-16 0.37
GLSK_HUMAN GLS Glutaminase kidney isoform, mitochondrial 4.441e-16 0.37
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 6.661e-16 0.44
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 6.661e-16 0.30
Q9I8A2_CHICK VATB Vacuolar proton pump subunit B 8.882e-16 0.30
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 9.992e-16 0.36
EGFR_MOUSE Egfr Epidermal growth factor receptor 1.221e-15 0.37
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.221e-15 0.36
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 3.442e-15 0.31
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 4.441e-15 0.39
CARM1_MOUSE Carm1 Histone-arginine methyltransferase CARM1 6.994e-15 0.29
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 8.105e-15 0.50
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 1.066e-14 0.32
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.177e-14 0.37
CATL1_HUMAN CTSL Cathepsin L1 1.277e-14 0.35
Q56D28_CAVPO CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells 1.732e-14 0.36
NEP_RABIT MME Neprilysin 1.787e-14 0.39
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 3.475e-14 0.38
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 3.486e-14 0.35
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 6.273e-14 0.33
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 6.284e-14 0.32
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 7.061e-14 0.34
PTN9_HUMAN PTPN9 Tyrosine-protein phosphatase non-receptor type 9 7.294e-14 0.33
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 7.916e-14 0.34
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 8.438e-14 0.31
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 8.504e-14 0.47
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 1.051e-13 0.34
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.287e-13 0.37
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 1.503e-13 0.49
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 1.704e-13 0.29
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 1.704e-13 0.29
DRD4_RAT Drd4 D(4) dopamine receptor 2.608e-13 0.31
CATL2_HUMAN CTSV Cathepsin L2 5.023e-13 0.32
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 6.295e-13 0.36
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 7.799e-13 0.40
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 9.779e-13 0.45
Q9FD53_STREE mvaD Diphosphomevalonate decarboxylase 1.043e-12 0.34
ARBK2_HUMAN GRK3 Beta-adrenergic receptor kinase 2 1.713e-12 0.30
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 2.086e-12 0.37
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 2.607e-12 0.37
LIPE_MOUSE Lipg Endothelial lipase 3.241e-12 0.46
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 3.403e-12 0.37
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 3.856e-12 0.45
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 4.025e-12 0.32
THA_HUMAN THRA Thyroid hormone receptor alpha 5.719e-12 0.43
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 5.811e-12 0.43
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 6.202e-12 0.31
LYOX_HUMAN LOX Protein-lysine 6-oxidase 6.369e-12 0.32
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 9.7e-12 0.29
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.086e-11 0.38
CBPA1_BOVIN CPA1 Carboxypeptidase A1 1.213e-11 0.34
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.216e-11 0.34
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 1.312e-11 0.33
DPO1_THEAQ polA DNA polymerase I, thermostable 1.52e-11 0.31
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.013e-11 0.38
PLD2_HUMAN PLD2 Phospholipase D2 2.035e-11 0.30
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 2.335e-11 0.33
THB_HUMAN THRB Thyroid hormone receptor beta 2.547e-11 0.43
CAN_CANAL NCE103 Carbonic anhydrase 2.643e-11 0.36
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 3.201e-11 0.33
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 4.631e-11 0.42
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 5.254e-11 0.33
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 5.353e-11 0.32
HRH1_CAVPO HRH1 Histamine H1 receptor 7.712e-11 0.38
KLF5_HUMAN KLF5 Krueppel-like factor 5 7.724e-11 0.48
PTPRO_HUMAN PTPRO Receptor-type tyrosine-protein phosphatase O 1.105e-10 0.29
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 1.509e-10 0.42
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 1.522e-10 0.28
HAOX2_RAT Hao2 Hydroxyacid oxidase 2 1.638e-10 0.31
ALDR_PIG AKR1B1 Aldo-keto reductase family 1 member B1 1.797e-10 0.35
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 4.187e-10 0.37
Q91H74_9FLAV Genome polyprotein 4.249e-10 0.29
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 4.284e-10 0.41
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 4.582e-10 0.36
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 4.922e-10 0.40
Q6DMN0_TOXGO CPL Cathepsin L 6.439e-10 0.29
FDFT_HUMAN FDFT1 Squalene synthase 6.999e-10 0.37
HRH2_CAVPO HRH2 Histamine H2 receptor 7.031e-10 0.36
PADI2_HUMAN PADI2 Protein-arginine deiminase type-2 7.541e-10 0.29
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 7.639e-10 0.32
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 8.25e-10 0.33
PLD1_HUMAN PLD1 Phospholipase D1 8.788e-10 0.29
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 9.151e-10 0.33
KLKB1_HUMAN KLKB1 Plasma kallikrein 9.563e-10 0.34
PYGL_RAT Pygl Glycogen phosphorylase, liver form 1.012e-09 0.28
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.206e-09 0.30
ECR_BOMMO EcR Ecdysone receptor 1.866e-09 0.32
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 1.974e-09 0.30
AK1A1_HUMAN AKR1A1 Aldo-keto reductase family 1 member A1 2.092e-09 0.31
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 3.32e-09 0.36
POLG_DEN26 Genome polyprotein 3.598e-09 0.29
LYAM2_HUMAN SELE E-selectin 5.071e-09 0.37
CMA1_HUMAN CMA1 Chymase 5.8e-09 0.42
CATL1_BOVIN CTSL Cathepsin L1 6.375e-09 0.31
CAH2_BOVIN CA2 Carbonic anhydrase 2 6.376e-09 0.37
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 7.167e-09 0.33
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 8.233e-09 0.43
CATS_HUMAN CTSS Cathepsin S 9.881e-09 0.35
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 1.45e-08 0.34
PTN2_HUMAN PTPN2 Tyrosine-protein phosphatase non-receptor type 2 1.838e-08 0.37
SCYD_MAGO7 SDH1 Scytalone dehydratase 1.975e-08 0.43
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 2.477e-08 0.42
LUCI_RENRE Coelenterazine h 2-monooxygenase 3.032e-08 0.29
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 3.192e-08 0.32
NK3R_CAVPO TACR3 Neuromedin-K receptor 3.394e-08 0.30
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 3.489e-08 0.38
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 4.286e-08 0.41
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 5.143e-08 0.30
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 5.175e-08 0.47
FSHR_HUMAN FSHR Follicle-stimulating hormone receptor 5.513e-08 0.31
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 6.354e-08 0.34
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 6.855e-08 0.38
HDAC2_HUMAN HDAC2 Histone deacetylase 2 6.978e-08 0.50
TRY1_HUMAN PRSS1 Trypsin-1 7.381e-08 0.46
CATG_HUMAN CTSG Cathepsin G 7.78e-08 0.37
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 8.245e-08 0.32
EST1_HUMAN CES1 Liver carboxylesterase 1 8.269e-08 0.30
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 8.348e-08 0.42
NEP_HUMAN MME Neprilysin 9.944e-08 0.36
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 1.103e-07 0.35
SPRE_HUMAN SPR Sepiapterin reductase 1.365e-07 0.28
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.658e-07 0.36
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 1.708e-07 0.40
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 1.79e-07 0.32
GRIA1_HUMAN GRIA1 Glutamate receptor 1 1.825e-07 0.32
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 1.835e-07 0.36
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 2.026e-07 0.37
Q76353_9HIV1 Integrase 2.849e-07 0.49
MMP10_HUMAN MMP10 Stromelysin-2 3.419e-07 0.34
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 3.771e-07 0.30
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 4.618e-07 0.35
KDM4B_HUMAN KDM4B Lysine-specific demethylase 4B 4.721e-07 0.43
HDAC9_HUMAN HDAC9 Histone deacetylase 9 4.837e-07 0.32
TA2R_MOUSE Tbxa2r Thromboxane A2 receptor 5.972e-07 0.30
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 6.039e-07 0.31
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 6.83e-07 0.29
OPRK_RAT Oprk1 Kappa-type opioid receptor 6.868e-07 0.33
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 7.516e-07 0.33
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 7.57e-07 0.31
EGLN2_HUMAN EGLN2 Egl nine homolog 2 8.423e-07 0.30
FA10_HUMAN F10 Coagulation factor X 8.791e-07 0.51
TYTR_TRYBB TPR Trypanothione reductase 9.7e-07 0.30
CHLE_HUMAN BCHE Cholinesterase 1.011e-06 0.37
OXDA_MOUSE Dao D-amino-acid oxidase 1.02e-06 0.32
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 1.076e-06 0.35
EST1_RABIT Liver carboxylesterase 1 1.138e-06 0.30
PDS_SYNE7 pds 15-cis-phytoene desaturase 1.172e-06 0.31
PD2R2_MOUSE Ptgdr2 Prostaglandin D2 receptor 2 1.389e-06 0.29
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 1.434e-06 0.32
Q72874_9HIV1 pol Pol polyprotein 1.445e-06 0.41
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 1.533e-06 0.38
CATB_HUMAN CTSB Cathepsin B 1.55e-06 0.32
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 1.581e-06 0.28
AAKG1_HUMAN PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 1.65e-06 0.31
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.663e-06 0.33
ACES_HUMAN ACHE Acetylcholinesterase 1.687e-06 0.36
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 2.197e-06 0.45
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 2.25e-06 0.32
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 2.417e-06 0.33
GRIA1_RAT Gria1 Glutamate receptor 1 2.642e-06 0.34
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 2.656e-06 0.39
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 2.845e-06 0.30
GRIA4_RAT Gria4 Glutamate receptor 4 2.874e-06 0.34
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.875e-06 0.32
NK3R_RAT Tacr3 Neuromedin-K receptor 3.599e-06 0.30
ITA2_HUMAN ITGA2 Integrin alpha-2 4.309e-06 0.32
GLUC_HUMAN GCG Glucagon 4.325e-06 0.33
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 5.426e-06 0.36
USP_DROME usp Protein ultraspiracle 5.632e-06 0.32
HDAC4_HUMAN HDAC4 Histone deacetylase 4 5.657e-06 0.33
SC5A7_HUMAN SLC5A7 High affinity choline transporter 1 5.897e-06 0.36
PLD1_RAT Pld1 Phospholipase D1 6.558e-06 0.29
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 6.67e-06 0.34
NK2R_MESAU TACR2 Substance-K receptor 6.796e-06 0.30
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 7.192e-06 0.38
MMP2_HUMAN MMP2 72 kDa type IV collagenase 7.841e-06 0.34
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 7.935e-06 0.31
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 8.567e-06 0.32
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 8.782e-06 0.40
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 9.319e-06 0.38

ZINC338689783

PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 1.997e-110 0.47
SYUA_HUMAN SNCA Alpha-synuclein 5.682e-97 0.47
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 1.939e-56 0.45
PLD2_HUMAN PLD2 Phospholipase D2 4.017e-50 0.47
PLD1_HUMAN PLD1 Phospholipase D1 1.8e-47 0.47
PA_I000X PA Polymerase acidic protein 1.053e-45 0.50
BCAT1_RAT Bcat1 Branched-chain-amino-acid aminotransferase, cytosolic 1.157e-39 0.31
BCAT2_RAT Bcat2 Branched-chain-amino-acid aminotransferase, mitochondrial 1.157e-39 0.31
GLUT4_RAT Slc2a4 Solute carrier family 2, facilitated glucose transporter member 4 1.332e-36 0.29
GTR8_HUMAN SLC2A8 Solute carrier family 2, facilitated glucose transporter member 8 1.332e-36 0.29
E2AK3_RAT Eif2ak3 Eukaryotic translation initiation factor 2-alpha kinase 3 1.215e-35 0.28
Q6P1E0_MOUSE Syk Tyrosine-protein kinase 2.094e-29 0.32
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 4.545e-29 0.35
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 2.89e-28 0.39
BCAT1_HUMAN BCAT1 Branched-chain-amino-acid aminotransferase, cytosolic 5.865e-28 0.31
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 7.947e-27 0.42
MMP13_MOUSE Mmp13 Collagenase 3 1.402e-26 0.31
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.59e-25 0.41
KCNA6_HUMAN KCNA6 Potassium voltage-gated channel subfamily A member 6 5.549e-25 0.48
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 2.479e-24 0.45
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 7.758e-24 0.36
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 1.817e-22 0.56
KPYK_STAAR pyk Pyruvate kinase 1.295e-21 0.36
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 5.755e-20 0.31
PLD1_RAT Pld1 Phospholipase D1 2.24e-19 0.47
CCKAR_RAT Cckar Cholecystokinin receptor type A 8.378e-19 0.45
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 2.804e-18 0.43
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 2.898e-18 0.29
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 1.836e-17 0.56
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 2.744e-17 0.43
PAR12_HUMAN PARP12 Protein mono-ADP-ribosyltransferase PARP12 3.331e-16 0.31
PAR16_HUMAN PARP16 Protein mono-ADP-ribosyltransferase PARP16 3.331e-16 0.31
SPRE_HUMAN SPR Sepiapterin reductase 3.331e-16 0.32
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 5.551e-16 0.31
LCK_MOUSE Lck Proto-oncogene tyrosine-protein kinase LCK 1.221e-15 0.34
KCNA4_HUMAN KCNA4 Potassium voltage-gated channel subfamily A member 4 5.329e-15 0.48
BLA1_STEMA Metallo-beta-lactamase L1 type 3 1.243e-14 0.43
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.532e-14 0.52
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 3.586e-14 0.39
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 4.685e-14 0.44
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 1.227e-13 0.36
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 2.004e-13 0.34
GPR52_HUMAN GPR52 G-protein coupled receptor 52 3.68e-13 0.33
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 4.131e-13 0.34
PAR14_HUMAN PARP14 Protein mono-ADP-ribosyltransferase PARP14 6.568e-13 0.31
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.803e-12 0.39
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 1.919e-12 0.33
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 3.194e-12 0.36
AOC2_HUMAN AOC2 Retina-specific copper amine oxidase 5.06e-12 0.29
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 6.878e-12 0.36
NOS3_BOVIN NOS3 Nitric oxide synthase, endothelial 9.892e-12 0.30
CXCR2_RABIT CXCR2 C-X-C chemokine receptor type 2 1.339e-11 0.28
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.618e-11 0.48
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 1.761e-11 0.39
FA10_HUMAN F10 Coagulation factor X 3.817e-11 0.39
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 9.598e-11 0.31
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 9.608e-11 0.46
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 1.041e-10 0.42
NOS1_RAT Nos1 Nitric oxide synthase, brain 2.112e-10 0.33
KCNN4_HUMAN KCNN4 Intermediate conductance calcium-activated potassium channel protein 4 2.177e-10 0.32
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 3.046e-10 0.35
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 1.049e-09 0.39
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 1.117e-09 0.34
DRD2_HUMAN DRD2 D(2) dopamine receptor 3.344e-09 0.48
CAH2_BOVIN CA2 Carbonic anhydrase 2 4.033e-09 0.39
HDAC1_HUMAN HDAC1 Histone deacetylase 1 4.081e-09 0.52
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 6.184e-09 0.34
RASH_HUMAN HRAS GTPase HRas 6.688e-09 0.34
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 7.319e-09 0.30
PERM_HUMAN MPO Myeloperoxidase 1.038e-08 0.31
Q7ZJM1_9HIV1 pol Integrase 1.058e-08 0.35
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 1.19e-08 0.39
MP2K7_HUMAN MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 1.233e-08 0.30
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 2.287e-08 0.34
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 4.442e-08 0.42
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 4.633e-08 0.30
DRD4_HUMAN DRD4 D(4) dopamine receptor 5.051e-08 0.44
OXDA_RAT Dao D-amino-acid oxidase 6.211e-08 0.35
HAOX2_RAT Hao2 Hydroxyacid oxidase 2 7.015e-08 0.34
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 9.501e-08 0.35
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.074e-07 0.32
EGFR_MOUSE Egfr Epidermal growth factor receptor 1.155e-07 0.31
TGFR1_MOUSE Tgfbr1 TGF-beta receptor type-1 1.185e-07 0.30
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 1.584e-07 0.30
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 1.803e-07 0.45
HDAC2_HUMAN HDAC2 Histone deacetylase 2 1.92e-07 0.40
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 2.38e-07 0.30
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 3.408e-07 0.38
TF_HUMAN F3 Tissue factor 8.054e-07 0.31
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 9.396e-07 0.29
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 1.023e-06 0.34
LGUL_HUMAN GLO1 Lactoylglutathione lyase 1.37e-06 0.31
HDAC6_HUMAN HDAC6 Histone deacetylase 6 2.123e-06 0.39
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 2.566e-06 0.37
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 3.016e-06 0.46
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 3.597e-06 0.28
CNR1_HUMAN CNR1 Cannabinoid receptor 1 3.664e-06 0.60
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 3.667e-06 0.30
STABP_HUMAN STAMBP STAM-binding protein 5.03e-06 0.30
OXDA_MOUSE Dao D-amino-acid oxidase 5.091e-06 0.28
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 6.339e-06 0.31
LYOX_HUMAN LOX Protein-lysine 6-oxidase 6.558e-06 0.29
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 7.11e-06 0.31
Q76353_9HIV1 Integrase 7.314e-06 0.36
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 8.728e-06 0.38

ZINC1169117622

MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 2.05e-96 0.40
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 1.487e-68 0.32
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 1.789e-36 0.30
SOAT1_MOUSE Soat1 Sterol O-acyltransferase 1 5.355e-25 0.33
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 1.443e-17 0.31
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 1.21e-14 0.34
ACOX1_RAT Acox1 Peroxisomal acyl-coenzyme A oxidase 1 2.121e-14 0.33
KCNQ2_MOUSE Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 1.587e-12 0.30
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 1.165e-10 0.31
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 1.389e-10 0.33
MMP8_RAT Mmp8 Neutrophil collagenase 4.608e-09 0.28
VE1_HPV11 E1 Replication protein E1 7.007e-09 0.31
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.703e-08 0.28
SCAF_HHV11 UL26 Capsid scaffolding protein 1.244e-07 0.28
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 2.467e-07 0.32
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 2.76e-07 0.31
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 2.881e-07 0.36
VKOR1_RAT Vkorc1 Vitamin K epoxide reductase complex subunit 1 4.055e-07 0.29
CEPT1_HUMAN CEPT1 Choline/ethanolaminephosphotransferase 1 4.527e-07 0.29
PA_I34A1 PA Polymerase acidic protein 5.55e-07 0.29
ACACA_HUMAN ACACA Acetyl-CoA carboxylase 1 2.149e-06 0.37
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 6.558e-06 0.29
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 7.112e-06 0.29
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 8.99e-06 0.29

ZINC1609567612

SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 2.725e-94 0.38
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.627e-77 0.37
LYOX_HUMAN LOX Protein-lysine 6-oxidase 1.355e-71 0.44
RXFP1_HUMAN RXFP1 Relaxin receptor 1 4.797e-68 0.33
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 8.144e-68 0.38
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 4.43e-53 0.44
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 1.38e-43 0.41
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 6.32e-42 0.42
BAP1_HUMAN BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1 1.713e-41 0.33
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 6.011e-38 0.37
GLUT4_RAT Slc2a4 Solute carrier family 2, facilitated glucose transporter member 4 1.71e-35 0.28
GTR8_HUMAN SLC2A8 Solute carrier family 2, facilitated glucose transporter member 8 1.71e-35 0.28
C3SLB7_ECOLX glmU Bifunctional protein GlmU 6.706e-35 0.32
LIMK2_HUMAN LIMK2 LIM domain kinase 2 6.032e-31 0.32
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 2.895e-29 0.44
AURKA_HUMAN AURKA Aurora kinase A 8.074e-26 0.35
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 4.044e-24 0.36
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 4.769e-24 0.44
O68720_YERPE yopH Targeted effector protein 9.183e-23 0.36
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 2.628e-22 0.38
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 4.064e-22 0.37
AURKB_HUMAN AURKB Aurora kinase B 8.523e-22 0.35
NRAM2_HUMAN SLC11A2 Natural resistance-associated macrophage protein 2 8.954e-22 0.39
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 4.286e-21 0.35
ARBK2_HUMAN GRK3 Beta-adrenergic receptor kinase 2 1.153e-20 0.32
RXFP2_HUMAN RXFP2 Relaxin receptor 2 2.318e-20 0.32
Q25615_ONCVO Chitinase 3.574e-20 0.31
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 7.545e-20 0.34
CLTR1_HUMAN CYSLTR1 Cysteinyl leukotriene receptor 1 1.939e-18 0.36
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 2.533e-18 0.37
LOXL2_RAT Loxl2 Lysyl oxidase homolog 2 6.229e-18 0.28
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 1.006e-17 0.28
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 1.104e-17 0.36
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.907e-17 0.29
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 1.11e-16 0.29
ARBK1_HUMAN GRK2 Beta-adrenergic receptor kinase 1 5.551e-16 0.32
RHOA_HUMAN RHOA Transforming protein RhoA 1.221e-15 0.39
LOXL3_HUMAN LOXL3 Lysyl oxidase homolog 3 2.22e-15 0.28
SHH_MOUSE Shh Sonic hedgehog protein 3.331e-15 0.32
LOXL2_MOUSE Loxl2 Lysyl oxidase homolog 2 5.44e-15 0.28
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 1.554e-14 0.35
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 4.328e-13 0.31
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 6.057e-13 0.29
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 2.757e-12 0.30
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 4.569e-12 0.30
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 8.291e-12 0.34
A6QR73_RAT Gpr39 G protein-coupled receptor 39 9.7e-12 0.29
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 1.06e-11 0.31
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 1.966e-11 0.35
G3I1B6_CRIGR 5-hydroxytryptamine receptor 3.072e-11 0.29
5HT1B_CRIGR HTR1B 5-hydroxytryptamine receptor 1B 4.156e-11 0.29
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 8.853e-11 0.32
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 1.163e-10 0.31
ANDR_MOUSE Ar Androgen receptor 1.31e-10 0.36
MBD2_HUMAN MBD2 Methyl-CpG-binding domain protein 2 1.522e-10 0.28
THRB_BOVIN F2 Prothrombin 1.526e-10 0.31
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 1.999e-10 0.30
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 4.938e-10 0.35
SENP7_HUMAN SENP7 Sentrin-specific protease 7 5.748e-10 0.38
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 6.801e-10 0.38
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 8.854e-10 0.33
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 1.213e-09 0.31
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 1.301e-09 0.30
GPR39_MOUSE Gpr39 G-protein coupled receptor 39 2.317e-09 0.29
EST1_HUMAN CES1 Liver carboxylesterase 1 2.692e-09 0.39
MEP50_HUMAN WDR77 Methylosome protein 50 2.777e-09 0.33
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 3.46e-09 0.33
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 5.983e-09 0.35
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 1.118e-08 0.36
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 1.169e-08 0.31
TRY1_BOVIN Cationic trypsin 1.171e-08 0.33
LIMK1_HUMAN LIMK1 LIM domain kinase 1 1.448e-08 0.31
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 2.735e-08 0.32
MET_HUMAN MET Hepatocyte growth factor receptor 3.999e-08 0.34
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 5.869e-08 0.30
NR1H4_HUMAN NR1H4 Bile acid receptor 5.968e-08 0.35
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 7.211e-08 0.35
IL6_HUMAN IL6 Interleukin-6 9.613e-08 0.30
ACRO_HUMAN ACR Acrosin 1.018e-07 0.35
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 1.072e-07 0.38
PLPL6_MOUSE Pnpla6 Neuropathy target esterase 1.142e-07 0.33
LUCI_PHOPY Luciferin 4-monooxygenase 1.307e-07 0.35
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.458e-07 0.31
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 2.556e-07 0.31
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 3.118e-07 0.28
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 3.521e-07 0.29
UROK_HUMAN PLAU Urokinase-type plasminogen activator 8.026e-07 0.39
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 1.446e-06 0.33
GALR3_HUMAN GALR3 Galanin receptor type 3 1.479e-06 0.33
SENP6_HUMAN SENP6 Sentrin-specific protease 6 1.713e-06 0.35
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 1.792e-06 0.35
TIE2_HUMAN TEK Angiopoietin-1 receptor 2.531e-06 0.35
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 4.057e-06 0.34
PI2R_HUMAN PTGIR Prostacyclin receptor 5.132e-06 0.31
TPA_HUMAN PLAT Tissue-type plasminogen activator 5.515e-06 0.33
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 6.407e-06 0.34
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 7.986e-06 0.35
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 8.156e-06 0.32
TRYP_PIG Trypsin 8.579e-06 0.31

ZINC337794008

COLA_CLOPE colA Collagenase ColA 6.553e-93 0.33
SYUA_HUMAN SNCA Alpha-synuclein 1.429e-57 0.34
SPRE_HUMAN SPR Sepiapterin reductase 5.389e-38 0.32
SCMU_MYCTU Secreted chorismate mutase 1.332e-36 0.29
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 2.894e-29 0.34
GBRA1_RAT Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 2.724e-25 0.34
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 7.991e-25 0.34
DPOL_HHV6U U38 DNA polymerase catalytic subunit 3.251e-24 0.33
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 5.35e-24 0.33
GBRG2_RAT Gabrg2 Gamma-aminobutyric acid receptor subunit gamma-2 5.773e-23 0.34
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 6.728e-19 0.45
PA_I000X PA Polymerase acidic protein 1.882e-17 0.33
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 3.299e-17 0.31
GBRA5_RAT Gabra5 Gamma-aminobutyric acid receptor subunit alpha-5 3.39e-17 0.34
GBRB3_RAT Gabrb3 Gamma-aminobutyric acid receptor subunit beta-3 1.11e-16 0.34
METC_ECOLI metC Cystathionine beta-lyase MetC 1.665e-15 0.36
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 7.749e-14 0.37
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 5.24e-13 0.34
BKRB2_RAT Bdkrb2 B2 bradykinin receptor 9.864e-13 0.38
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 9.915e-13 0.38
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 4.933e-12 0.37
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 5.986e-11 0.37
CRTM_STAAU crtM 4,4'-diapophytoene synthase 8.295e-11 0.33
Q9UM81_HUMAN PTPsigma PTPsigma-(Brain) 1.289e-10 0.28
TYTR_TRYCR TPR Trypanothione reductase 1.691e-10 0.33
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 7.147e-10 0.34
M9TGV3_MYCTX inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 9.049e-10 0.33
AROQ_STRCO aroQ 3-dehydroquinate dehydratase 1.37e-09 0.30
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 1.516e-09 0.30
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 1.581e-09 0.32
O31272_9GAMM imiS Beta-lactamase 2.791e-09 0.29
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 6.674e-09 0.37
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 7.253e-09 0.38
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 9.807e-09 0.38
CAN_CANAL NCE103 Carbonic anhydrase 1.063e-08 0.37
MTR1C_XENLA mtnr1c Melatonin receptor type 1C 1.112e-08 0.29
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 2.94e-08 0.31
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 3.137e-08 0.36
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 7.146e-08 0.33
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.435e-07 0.31
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 2.785e-07 0.36
5HT1D_RAT Htr1d 5-hydroxytryptamine receptor 1D 2.833e-07 0.31
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 3.071e-07 0.31
EGFR_MOUSE Egfr Epidermal growth factor receptor 4.905e-07 0.29
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 6.348e-07 0.34
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 7.71e-07 0.31
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 7.975e-07 0.31
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 9.648e-07 0.37
BLA1_STEMA Metallo-beta-lactamase L1 type 3 1.089e-06 0.30
GRIK3_HUMAN GRIK3 Glutamate receptor ionotropic, kainate 3 1.435e-06 0.29
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.519e-06 0.40
EST1_RABIT Liver carboxylesterase 1 1.682e-06 0.29
CAH2_HUMAN CA2 Carbonic anhydrase 2 2.563e-06 0.40
CAH7_HUMAN CA7 Carbonic anhydrase 7 3.369e-06 0.38
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 4.091e-06 0.32
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 4.588e-06 0.46
CASP5_HUMAN CASP5 Caspase-5 5.99e-06 0.29
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 9.393e-06 0.38

ZINC270433911

ETHR_MYCTU ethR HTH-type transcriptional regulator EthR 1.971e-90 0.40
GRM5_HUMAN GRM5 Metabotropic glutamate receptor 5 1.396e-40 0.42
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 2.477e-38 0.40
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 1.696e-29 0.34
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 4.771e-29 0.34
GBRA6_RAT Gabra6 Gamma-aminobutyric acid receptor subunit alpha-6 2.692e-26 0.30
SMO_HUMAN SMO Smoothened homolog 9.917e-22 0.35
LIMK2_HUMAN LIMK2 LIM domain kinase 2 3.886e-15 0.33
Q5NGQ3_FRATT fabI Enoyl-[acyl-carrier-protein] reductase [NADH] 1.191e-12 0.31
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 2.702e-11 0.33
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 1.001e-10 0.34
CDN1A_HUMAN CDKN1A Cyclin-dependent kinase inhibitor 1 5.771e-09 0.30
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 6.584e-09 0.35
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 2.905e-07 0.30
GBRG2_RAT Gabrg2 Gamma-aminobutyric acid receptor subunit gamma-2 9.708e-07 0.30
GASR_CANLF CCKBR Gastrin/cholecystokinin type B receptor 4.05e-06 0.29
RXFP1_HUMAN RXFP1 Relaxin receptor 1 6.019e-06 0.30
NPY5R_MOUSE Npy5r Neuropeptide Y receptor type 5 6.607e-06 0.35

ZINC1641229345

SUCR1_HUMAN SUCNR1 Succinate receptor 1 3.393e-87 0.46
GLSK_HUMAN GLS Glutaminase kidney isoform, mitochondrial 1.261e-60 0.35
SUCR1_RAT Sucnr1 Succinate receptor 1 1.137e-55 0.41
OXGR1_HUMAN OXGR1 2-oxoglutarate receptor 1 8.17e-43 0.41
TYTR_CRIFA TPR Trypanothione reductase 2.644e-41 0.33
MURI_LACFE murI Glutamate racemase 1.579e-38 0.31
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 5.043e-36 0.34
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 5.226e-34 0.36
CRTM_STAAU crtM 4,4'-diapophytoene synthase 2.562e-27 0.31
CLTR1_CAVPO CYSLTR1 Cysteinyl leukotriene receptor 1 1.467e-26 0.38
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 2.17e-19 0.37
KS6B2_HUMAN RPS6KB2 Ribosomal protein S6 kinase beta-2 2.971e-19 0.31
C6ARS9_RHILS lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.039e-18 0.30
POLG_CXB3N Genome polyprotein 2.313e-18 0.34
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 6.51e-18 0.30
IDE_HUMAN IDE Insulin-degrading enzyme 4.978e-17 0.35
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 1.11e-16 0.39
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 6.661e-16 0.34
CLTR1_HUMAN CYSLTR1 Cysteinyl leukotriene receptor 1 7.772e-16 0.38
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 8.882e-16 0.34
DPOL_HHV6U U38 DNA polymerase catalytic subunit 2.331e-15 0.29
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 2.198e-14 0.30
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 4.652e-14 0.37
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 7.649e-14 0.37
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.007e-13 0.33
HDAC1_RAT Hdac1 Histone deacetylase 1 8.35e-13 0.32
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 1.435e-12 0.38
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 1.435e-12 0.38
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 1.643e-12 0.34
TYTR_TRYCR TPR Trypanothione reductase 4.098e-12 0.35
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 4.223e-12 0.34
DLG4_HUMAN DLG4 Disks large homolog 4 4.355e-12 0.31
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 6.365e-12 0.47
Q9ZTP8_MAIZE hd1b Histone deacetylase 7.932e-12 0.29
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 2.183e-11 0.34
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 3.161e-11 0.34
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 3.184e-11 0.46
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 3.954e-11 0.37
HDAC1_HUMAN HDAC1 Histone deacetylase 1 4.001e-11 0.52
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 2.044e-10 0.36
HDAC8_HUMAN HDAC8 Histone deacetylase 8 2.328e-10 0.52
NANA_STREE nanA Sialidase A 4.398e-10 0.29
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 3.103e-09 0.31
MC5R_HUMAN MC5R Melanocortin receptor 5 3.215e-09 0.37
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 1.121e-08 0.34
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 1.484e-08 0.30
HDA11_HUMAN HDAC11 Histone deacetylase 11 1.568e-08 0.33
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 1.709e-08 0.30
NEP_HUMAN MME Neprilysin 2.721e-08 0.33
FCER2_HUMAN FCER2 Low affinity immunoglobulin epsilon Fc receptor 2.73e-08 0.32
MC3R_MOUSE Mc3r Melanocortin receptor 3 2.953e-08 0.28
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 7.127e-08 0.29
EGLN1_HUMAN EGLN1 Egl nine homolog 1 7.139e-08 0.32
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 1.205e-07 0.29
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.242e-07 0.31
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 1.258e-07 0.33
AOFB_RAT Maob Amine oxidase [flavin-containing] B 1.398e-07 0.38
TRY1_BOVIN Cationic trypsin 2.245e-07 0.33
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 2.571e-07 0.31
MDHM_PIG MDH2 Malate dehydrogenase, mitochondrial 3.071e-07 0.31
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 3.187e-07 0.31
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 3.513e-07 0.29
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 5.378e-07 0.33
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 7.679e-07 0.30
PLPL6_MOUSE Pnpla6 Neuropathy target esterase 7.69e-07 0.29
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 7.755e-07 0.31
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.09e-06 0.30
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 1.448e-06 0.36
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 1.482e-06 0.35
FA7_HUMAN F7 Coagulation factor VII 2.799e-06 0.33
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.849e-06 0.29
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 4.419e-06 0.33
MC4R_MOUSE Mc4r Melanocortin receptor 4 5.73e-06 0.28
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 9.011e-06 0.29

ZINC826319402

P2Y14_MOUSE P2ry14 P2Y purinoceptor 14 1.443e-84 0.34
FGFR3_HUMAN FGFR3 Fibroblast growth factor receptor 3 3.355e-77 0.38
BCR_HUMAN BCR Breakpoint cluster region protein 9.618e-72 0.41
ANM3_HUMAN PRMT3 Protein arginine N-methyltransferase 3 7.602e-69 0.40
GYRB_STRPN gyrB DNA gyrase subunit B 3.378e-51 0.33
Q7X1P7_STREE parE DNA topoisomerase (ATP-hydrolyzing) 3.378e-51 0.33
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 2.082e-42 0.38
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 6.726e-41 0.38
PLPL2_HUMAN PNPLA2 Patatin-like phospholipase domain-containing protein 2 1.921e-39 0.31
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.208e-37 0.39
PARE_ECOLI parE DNA topoisomerase 4 subunit B 2.001e-36 0.30
TIE2_HUMAN TEK Angiopoietin-1 receptor 1.701e-35 0.36
GYRB_STAAU gyrB DNA gyrase subunit B 7.753e-33 0.37
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 7.79e-33 0.39
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 6.558e-28 0.35
GYRA_STAAU gyrA DNA gyrase subunit A 2.01e-27 0.37
BLM_HUMAN BLM Bloom syndrome protein 1.248e-24 0.32
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 1.287e-21 0.34
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 1.902e-21 0.41
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 3.262e-21 0.36
TF_HUMAN F3 Tissue factor 6.986e-21 0.38
ARBK1_HUMAN GRK2 Beta-adrenergic receptor kinase 1 5.619e-20 0.33
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 1.22e-19 0.39
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 1.338e-19 0.35
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 5.066e-19 0.34
AGTR1_HUMAN AGTR1 Type-1 angiotensin II receptor 2.941e-17 0.33
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 3.405e-17 0.38
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 3.331e-16 0.32
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 5.551e-16 0.34
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 1.443e-15 0.36
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.887e-15 0.34
DDX3X_HUMAN DDX3X ATP-dependent RNA helicase DDX3X 2.109e-15 0.29
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 2.776e-15 0.38
BLK_HUMAN BLK Tyrosine-protein kinase Blk 5.551e-15 0.34
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 6.661e-15 0.39
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 2.764e-14 0.32
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 3.02e-14 0.35
CNR1_HUMAN CNR1 Cannabinoid receptor 1 5.684e-14 0.40
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 7.483e-14 0.38
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 9.54e-13 0.32
ARBK2_HUMAN GRK3 Beta-adrenergic receptor kinase 2 1.399e-12 0.32
CCKAR_RAT Cckar Cholecystokinin receptor type A 1.889e-12 0.36
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 2.619e-12 0.39
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 3.458e-12 0.36
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 8.784e-12 0.34
TESK2_HUMAN TESK2 Dual specificity testis-specific protein kinase 2 9.7e-12 0.29
FRK_HUMAN FRK Tyrosine-protein kinase FRK 2.766e-11 0.34
O96526_LEIMA CRK3 Cdc2-related kinase 3.305e-11 0.33
GYRB_MYCSM gyrB DNA gyrase subunit B 3.453e-11 0.32
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4.633e-11 0.32
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 6.155e-11 0.35
TASP1_HUMAN TASP1 Threonine aspartase 1 8.4e-11 0.29
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 9.055e-11 0.34
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 1.169e-10 0.32
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 3.382e-10 0.38
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 4.011e-10 0.32
LCK_MOUSE Lck Proto-oncogene tyrosine-protein kinase LCK 5.194e-10 0.31
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 1.088e-09 0.31
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 1.983e-09 0.34
Q76129_9HIV1 gag Structural capsid protein 2.052e-09 0.34
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 2.144e-09 0.31
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 2.215e-09 0.33
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 2.986e-09 0.34
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 3.127e-09 0.32
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 3.144e-09 0.32
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 3.406e-09 0.32
5HT2C_MOUSE Htr2c 5-hydroxytryptamine receptor 2C 5.367e-09 0.30
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 6.474e-09 0.32
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 7.415e-09 0.35
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 9.562e-09 0.32
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 1.084e-08 0.33
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 1.432e-08 0.39
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 1.509e-08 0.32
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 2.085e-08 0.34
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 2.119e-08 0.34
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 4.265e-08 0.32
KPCA_HUMAN PRKCA Protein kinase C alpha type 5.934e-08 0.36
LCK_HUMAN LCK Tyrosine-protein kinase Lck 8.495e-08 0.34
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 8.775e-08 0.30
KDM2B_HUMAN KDM2B Lysine-specific demethylase 2B 9.06e-08 0.34
NLK_HUMAN NLK Serine/threonine-protein kinase NLK 1.27e-07 0.28
BTK_HUMAN BTK Tyrosine-protein kinase BTK 1.509e-07 0.35
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 1.54e-07 0.32
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 1.768e-07 0.30
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 1.914e-07 0.32
HAOX2_RAT Hao2 Hydroxyacid oxidase 2 2.018e-07 0.32
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 2.022e-07 0.32
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 2.951e-07 0.34
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 3.085e-07 0.29
KS6A5_HUMAN RPS6KA5 Ribosomal protein S6 kinase alpha-5 3.34e-07 0.31
LIMK1_HUMAN LIMK1 LIM domain kinase 1 3.773e-07 0.32
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 3.888e-07 0.34
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 4.177e-07 0.29
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 4.191e-07 0.33
PLK4_HUMAN PLK4 Serine/threonine-protein kinase PLK4 4.343e-07 0.32
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 4.409e-07 0.30
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 4.509e-07 0.34
AKT3_HUMAN AKT3 RAC-gamma serine/threonine-protein kinase 5.216e-07 0.30
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 5.568e-07 0.32
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 5.958e-07 0.38
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 7.114e-07 0.32
CDK19_HUMAN CDK19 Cyclin-dependent kinase 19 7.609e-07 0.32
AURKB_HUMAN AURKB Aurora kinase B 8.549e-07 0.34
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 8.768e-07 0.32
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 9.69e-07 0.32
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 1.331e-06 0.30
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 1.432e-06 0.34
PSBA_SPIOL psbA Photosystem II protein D1 1.472e-06 0.30
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 1.688e-06 0.32
KC1G2_HUMAN CSNK1G2 Casein kinase I isoform gamma-2 1.985e-06 0.31
PRKX_HUMAN PRKX cAMP-dependent protein kinase catalytic subunit PRKX 2.041e-06 0.31
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 2.15e-06 0.33
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 2.456e-06 0.30
LDLR_HUMAN LDLR Low-density lipoprotein receptor 2.631e-06 0.29
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 3.307e-06 0.31
MATK_HUMAN MATK Megakaryocyte-associated tyrosine-protein kinase 3.785e-06 0.31
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 3.932e-06 0.32
RXFP1_HUMAN RXFP1 Relaxin receptor 1 4.707e-06 0.31
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 4.869e-06 0.32
GYRB_MYCTU gyrB DNA gyrase subunit B 4.957e-06 0.28
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 4.986e-06 0.40
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 5.463e-06 0.28
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 5.509e-06 0.29
SYMC_HUMAN MARS1 Methionine--tRNA ligase, cytoplasmic 8.965e-06 0.30
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 8.971e-06 0.30

ZINC80128108

TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 1.931e-77 0.34
CTNB1_HUMAN CTNNB1 Catenin beta-1 2.048e-71 0.34
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 6.867e-65 0.39
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 1.634e-63 0.30
TRPV1_CAVPO Trpv1 Transient receptor potential cation channel subfamily V member 1 3.875e-36 0.29
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 9.772e-30 0.39
SHH_MOUSE Shh Sonic hedgehog protein 2.429e-29 0.33
GYRA_STAAU gyrA DNA gyrase subunit A 5.712e-29 0.37
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 6.687e-26 0.48
CEPT1_HUMAN CEPT1 Choline/ethanolaminephosphotransferase 1 4.291e-25 0.36
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 1.241e-24 0.36
TGT_HUMAN QTRT1 Queuine tRNA-ribosyltransferase catalytic subunit 1 4.633e-23 0.28
PFKA_TRYCC pfk ATP-dependent 6-phosphofructokinase 5.679e-23 0.33
PFKA_TRYBB pfk ATP-dependent 6-phosphofructokinase 1.991e-21 0.33
UT1_RAT Slc14a1 Urea transporter 1 2.693e-21 0.30
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 3.792e-20 0.32
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 4.919e-20 0.36
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 2.322e-19 0.31
RNH1_HUMAN RNASEH1 Ribonuclease H1 6.621e-19 0.29
PAR12_HUMAN PARP12 Protein mono-ADP-ribosyltransferase PARP12 8.175e-19 0.36
KS6B2_HUMAN RPS6KB2 Ribosomal protein S6 kinase beta-2 1.171e-18 0.29
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.657e-18 0.30
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 4.879e-18 0.29
GYRB_STAAU gyrB DNA gyrase subunit B 4.912e-18 0.37
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 9.819e-18 0.44
PCKGC_RAT Pck1 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] 1.874e-17 0.29
FUCO_BOVIN FUCA1 Tissue alpha-L-fucosidase 1.953e-17 0.36
TERT_HUMAN TERT Telomerase reverse transcriptase 2.153e-17 0.37
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 2.391e-17 0.45
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 8.882e-16 0.38
Q8IL11_PLAF7 M17 leucyl aminopeptidase 1.554e-15 0.33
PCKGC_HUMAN PCK1 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] 3.331e-15 0.29
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 1.321e-14 0.36
PDE9A_HUMAN PDE9A High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 5.163e-14 0.35
FPRS1_MOUSE Fpr-s1 Formyl peptide receptor-related sequence 1 8.615e-14 0.28
Q38C41_TRYB2 Phosphotransferase 4.505e-13 0.39
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 4.807e-13 0.33
PARP2_HUMAN PARP2 Poly [ADP-ribose] polymerase 2 6.479e-13 0.42
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 7.054e-13 0.29
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 8.387e-13 0.31
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 1.018e-12 0.35
TYSY_MOUSE Tyms Thymidylate synthase 2.545e-12 0.31
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 3.179e-12 0.36
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 3.801e-12 0.44
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 3.978e-12 0.33
PRIO_SHEEP PRNP Major prion protein 8.302e-12 0.29
BXE_CLOBO botE Botulinum neurotoxin type E 1.508e-11 0.28
PARP4_HUMAN PARP4 Protein mono-ADP-ribosyltransferase PARP4 2.274e-11 0.36
BGLR_HUMAN GUSB Beta-glucuronidase 5.476e-11 0.30
Q25615_ONCVO Chitinase 6.662e-11 0.31
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 1.289e-10 0.28
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 1.661e-10 0.31
ETHR_MYCTU ethR HTH-type transcriptional regulator EthR 1.707e-10 0.34
ANM3_HUMAN PRMT3 Protein arginine N-methyltransferase 3 2.158e-10 0.31
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 4.055e-10 0.42
FUCO_HUMAN FUCA1 Tissue alpha-L-fucosidase 4.567e-10 0.36
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 5.888e-10 0.31
TYSY_HUMAN TYMS Thymidylate synthase 8.405e-10 0.32
Q76353_9HIV1 Integrase 1.742e-09 0.37
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 1.793e-09 0.30
SENP6_HUMAN SENP6 Sentrin-specific protease 6 1.993e-09 0.42
PRIO_HUMAN PRNP Major prion protein 2.25e-09 0.32
PDE1B_HUMAN PDE1B Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B 6.417e-09 0.29
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 8.081e-09 0.32
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 9.258e-09 0.29
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 1.005e-08 0.36
HIF1A_HUMAN HIF1A Hypoxia-inducible factor 1-alpha 1.036e-08 0.35
C1R_HUMAN C1R Complement C1r subcomponent 1.291e-08 0.30
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 1.37e-08 0.29
SENP7_HUMAN SENP7 Sentrin-specific protease 7 2.147e-08 0.42
CETP_HUMAN CETP Cholesteryl ester transfer protein 3.161e-08 0.34
ITA3_HUMAN ITGA3 Integrin alpha-3 4.45e-08 0.28
SCAF_HHV11 UL26 Capsid scaffolding protein 4.982e-08 0.30
REV1_HUMAN REV1 DNA repair protein REV1 7.127e-08 0.29
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 8.668e-08 0.33
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 9.725e-08 0.33
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 1.612e-07 0.31
PANK3_HUMAN PANK3 Pantothenate kinase 3 1.934e-07 0.29
WNT3A_HUMAN WNT3A Protein Wnt-3a 3.139e-07 0.29
KCNH3_HUMAN KCNH3 Potassium voltage-gated channel subfamily H member 3 3.396e-07 0.29
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 3.487e-07 0.42
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 4.205e-07 0.42
PRIO_MESAU PRNP Major prion protein 5.181e-07 0.32
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 5.949e-07 0.36
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 6.985e-07 0.48
AURKB_HUMAN AURKB Aurora kinase B 7.339e-07 0.38
GYRB_MYCS2 gyrB DNA gyrase subunit B 1.142e-06 0.28
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 1.172e-06 0.32
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 1.223e-06 0.35
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 1.248e-06 0.33
ACES_ELEEL ache Acetylcholinesterase 1.322e-06 0.35
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 1.328e-06 0.36
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 1.328e-06 0.36
LDLR_HUMAN LDLR Low-density lipoprotein receptor 1.418e-06 0.30
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 1.639e-06 0.33
CASP9_HUMAN CASP9 Caspase-9 1.703e-06 0.42
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 1.971e-06 0.32
UROK_HUMAN PLAU Urokinase-type plasminogen activator 2.047e-06 0.32
NPY5R_RAT Npy5r Neuropeptide Y receptor type 5 2.089e-06 0.29
PERM_HUMAN MPO Myeloperoxidase 2.55e-06 0.30
AURKA_HUMAN AURKA Aurora kinase A 2.706e-06 0.38
Q7ZJM1_9HIV1 pol Integrase 2.75e-06 0.37
CLTR1_CAVPO CYSLTR1 Cysteinyl leukotriene receptor 1 2.839e-06 0.35
LUCI_AQULA Luciferin 4-monooxygenase 3.186e-06 0.31
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 3.507e-06 0.33
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 3.581e-06 0.32
LYOX_HUMAN LOX Protein-lysine 6-oxidase 3.933e-06 0.30
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 5.429e-06 0.31
C3SLB7_ECOLX glmU Bifunctional protein GlmU 5.463e-06 0.28
CXCR2_HUMAN CXCR2 C-X-C chemokine receptor type 2 6.782e-06 0.32
CYSP_TRYCR Cruzipain 6.863e-06 0.32
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 7.25e-06 0.42
SENP8_HUMAN SENP8 Sentrin-specific protease 8 7.385e-06 0.42
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 7.842e-06 0.30

ZINC799420985

MDHM_PIG MDH2 Malate dehydrogenase, mitochondrial 4.407e-76 0.34
T23O_MOUSE Tdo2 Tryptophan 2,3-dioxygenase 2.187e-45 0.37
PERM_HUMAN MPO Myeloperoxidase 9.868e-41 0.36
T23O_RAT Tdo2 Tryptophan 2,3-dioxygenase 7.655e-11 0.29
MOT4_HUMAN SLC16A3 Monocarboxylate transporter 4 5.529e-10 0.31
MTSI_SPISQ sssIM CPG DNA methylase 3.108e-09 0.29
SPRE_HUMAN SPR Sepiapterin reductase 5.378e-09 0.34
AOFB_RAT Maob Amine oxidase [flavin-containing] B 2.16e-07 0.34
Q3Y5H1_9GAMC 3C-like protease 7.429e-07 0.31
SYUA_HUMAN SNCA Alpha-synuclein 1.148e-06 0.31
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 2.773e-06 0.31
Q9JN24_ECOLX def Peptide deformylase 4.565e-06 0.37
OXDA_PIG DAO D-amino-acid oxidase 5.999e-06 0.30
NK2R_RAT Tacr2 Substance-K receptor 6.255e-06 0.29
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 9.025e-06 0.33

ZINC243846808

LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 6.827e-75 0.69
PERM_HUMAN MPO Myeloperoxidase 1.773e-66 0.46
SPRE_HUMAN SPR Sepiapterin reductase 2.492e-57 0.42
T23O_MOUSE Tdo2 Tryptophan 2,3-dioxygenase 9.296e-56 0.35
LN28A_MOUSE Lin28a Protein lin-28 homolog A 1.52e-40 0.32
SYUA_HUMAN SNCA Alpha-synuclein 1.026e-35 0.36
NK2R_RAT Tacr2 Substance-K receptor 2.38e-35 0.38
PNMT_HUMAN PNMT Phenylethanolamine N-methyltransferase 5.532e-28 0.32
TA2R_RAT Tbxa2r Thromboxane A2 receptor 1.405e-23 0.36
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 9.274e-23 0.43
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 7.84e-22 0.47
T23O_RAT Tdo2 Tryptophan 2,3-dioxygenase 6.646e-21 0.30
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.829e-18 0.49
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 7.232e-18 0.42
CAH2_BOVIN CA2 Carbonic anhydrase 2 1.854e-17 0.43
5HT1B_GORGO HTR1B 5-hydroxytryptamine receptor 1B 3.422e-17 0.33
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 8.105e-15 0.35
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 9.504e-14 0.34
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.152e-13 0.41
HRH3_CAVPO HRH3 Histamine H3 receptor 1.955e-13 0.37
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 2.061e-13 0.36
5HT1D_RAT Htr1d 5-hydroxytryptamine receptor 1D 2.84e-11 0.33
KPYM_HUMAN PKM Pyruvate kinase PKM 2.958e-11 0.30
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 1.387e-10 0.35
GCR_HUMAN NR3C1 Glucocorticoid receptor 1.445e-09 0.50
T23O_HUMAN TDO2 Tryptophan 2,3-dioxygenase 2.714e-09 0.34
GLRA3_HUMAN GLRA3 Glycine receptor subunit alpha-3 3.304e-09 0.31
MEP1B_HUMAN MEP1B Meprin A subunit beta 4.761e-09 0.31
MTR1C_XENLA mtnr1c Melatonin receptor type 1C 5.155e-09 0.30
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 9.308e-09 0.47
LEF_BACAN lef Lethal factor 1.148e-08 0.32
MGAT3_HUMAN MGAT3 Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase 2.242e-08 0.35
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 4.803e-08 0.41
MCR_HUMAN NR3C2 Mineralocorticoid receptor 8.941e-08 0.38
Q8MI13_BOVIN 5htr1d 5-hydroxytryptamine 1D receptor 2.353e-07 0.33
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 3.544e-07 0.49
FABI_ECOLI fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 3.916e-07 0.31
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 6.651e-07 0.33
CAN1_RAT Capn1 Calpain-1 catalytic subunit 6.762e-07 0.34
KPYK_STAAR pyk Pyruvate kinase 8.189e-07 0.34
TA2R_MOUSE Tbxa2r Thromboxane A2 receptor 1.166e-06 0.28
5HT1D_PIG HTR1D 5-hydroxytryptamine receptor 1D 1.372e-06 0.33
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 2.089e-06 0.35
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 2.241e-06 0.33
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 2.544e-06 0.33
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 2.784e-06 0.31
MOGT2_HUMAN MOGAT2 2-acylglycerol O-acyltransferase 2 3.064e-06 0.31
CHLE_HUMAN BCHE Cholinesterase 5.085e-06 0.35
THAS_HUMAN TBXAS1 Thromboxane-A synthase 7.716e-06 0.32
PAK4_HUMAN PAK4 Serine/threonine-protein kinase PAK 4 8.558e-06 0.35

ZINC112861928

PANK1_HUMAN PANK1 Pantothenate kinase 1 1.472e-69 0.31
PANK3_HUMAN PANK3 Pantothenate kinase 3 2.579e-42 0.31
PANK2_HUMAN PANK2 Pantothenate kinase 2, mitochondrial 5.748e-39 0.31
GYRA_STAAU gyrA DNA gyrase subunit A 1.465e-18 0.32
RXFP2_HUMAN RXFP2 Relaxin receptor 2 3.72e-18 0.29
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 5.161e-18 0.29
WNK2_HUMAN WNK2 Serine/threonine-protein kinase WNK2 6.229e-18 0.28
TERT_HUMAN TERT Telomerase reverse transcriptase 1.341e-17 0.32
CNR2_RAT Cnr2 Cannabinoid receptor 2 1.11e-16 0.45
HDAC2_HUMAN HDAC2 Histone deacetylase 2 5.551e-16 0.38
5HT1D_PIG HTR1D 5-hydroxytryptamine receptor 1D 3.244e-12 0.32
HDAC1_HUMAN HDAC1 Histone deacetylase 1 4.336e-12 0.38
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.028e-11 0.30
GYRB_STAAU gyrB DNA gyrase subunit B 1.488e-11 0.32
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 3.656e-11 0.40
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 8.373e-11 0.36
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 1.162e-10 0.32
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.241e-10 0.38
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 4.513e-09 0.31
KLF5_HUMAN KLF5 Krueppel-like factor 5 2.981e-08 0.44
HDAC3_HUMAN HDAC3 Histone deacetylase 3 5.744e-08 0.38
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 9.891e-08 0.39
PLK2_HUMAN PLK2 Serine/threonine-protein kinase PLK2 2.168e-07 0.30
CNR2_HUMAN CNR2 Cannabinoid receptor 2 2.891e-07 0.46
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 4.54e-07 0.34
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.819e-06 0.30
HDAC6_HUMAN HDAC6 Histone deacetylase 6 2.54e-06 0.38

ZINC1608857092

KMO_MOUSE Kmo Kynurenine 3-monooxygenase 5.33e-66 0.38
KMO_HUMAN KMO Kynurenine 3-monooxygenase 3.041e-56 0.39
HD_HUMAN HTT Huntingtin 2.053e-18 0.33
KMO_RAT Kmo Kynurenine 3-monooxygenase 2.465e-14 0.38
PGLD_CAMJE pglD UDP-N-acetylbacillosamine N-acetyltransferase 1.608e-13 0.29
HCAR2_RAT Hcar2 Hydroxycarboxylic acid receptor 2 3.164e-13 0.31
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 1.161e-10 0.35
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 2.351e-10 0.33
DOPO_RAT Dbh Dopamine beta-hydroxylase 1.813e-08 0.28
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 8.991e-08 0.33
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 1.288e-07 0.30
MDHM_PIG MDH2 Malate dehydrogenase, mitochondrial 3.814e-07 0.30
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.574e-06 0.33

ZINC1569946872

CEPT1_HUMAN CEPT1 Choline/ethanolaminephosphotransferase 1 3.553e-63 0.34
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 1.09e-57 0.35
TNKS1_MOUSE Tnks Poly [ADP-ribose] polymerase tankyrase-1 6.705e-36 0.28
TNKS2_MOUSE Tnks2 Poly [ADP-ribose] polymerase tankyrase-2 6.705e-36 0.28
CYC_HUMAN CYCS Cytochrome c 7.62e-36 0.28
GRM5_MOUSE Grm5 Metabotropic glutamate receptor 5 3.252e-31 0.31
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 2.531e-29 0.35
KC1A_BOVIN CSNK1A1 Casein kinase I isoform alpha 7.193e-24 0.29
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 2.057e-21 0.31
SHH_MOUSE Shh Sonic hedgehog protein 3.355e-17 0.32
STXA_SHIDY stxA Shiga toxin subunit A 2.22e-16 0.32
BGLR_HUMAN GUSB Beta-glucuronidase 4.441e-16 0.35
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 2.442e-15 0.35
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 8.105e-14 0.30
Q38C41_TRYB2 Phosphotransferase 1.249e-13 0.29
KC1D_RAT Csnk1d Casein kinase I isoform delta 6.033e-13 0.29
HDAC1_HUMAN HDAC1 Histone deacetylase 1 7.02e-13 0.43
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 3.238e-11 0.31
KLF5_HUMAN KLF5 Krueppel-like factor 5 1.641e-10 0.41
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 2.186e-10 0.35
HPSE_HUMAN HPSE Heparanase 3.206e-10 0.33
PIR_HUMAN PIR Pirin 5.732e-10 0.29
GPR35_HUMAN GPR35 G-protein coupled receptor 35 7.213e-10 0.35
PRTN3_HUMAN PRTN3 Myeloblastin 9.246e-10 0.29
HDAC2_HUMAN HDAC2 Histone deacetylase 2 1.165e-09 0.32
NR1H4_HUMAN NR1H4 Bile acid receptor 1.369e-09 0.35
Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 2.766e-09 0.31
STRP_STRP1 ska Streptokinase A 1.371e-08 0.39
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 3.716e-08 0.52
A5H660_SCHMA HDAC8 Histone deacetylase 8 3.846e-08 0.30
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 7.602e-08 0.34
RXFP1_HUMAN RXFP1 Relaxin receptor 1 7.703e-08 0.32
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 7.831e-08 0.42
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 1.729e-07 0.36
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.883e-07 0.33
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 2.08e-07 0.31
A3KMY8_BOVIN GUSB Beta-glucuronidase 2.349e-07 0.32
WNT3A_MOUSE Wnt3a Protein Wnt-3a 2.617e-07 0.28
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 5.452e-07 0.33
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 6.65e-07 0.36
MK11_HUMAN MAPK11 Mitogen-activated protein kinase 11 7.379e-07 0.41
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 8.98e-07 0.33
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 1.606e-06 0.29
PRIO_SHEEP PRNP Major prion protein 2.558e-06 0.29
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 2.728e-06 0.31
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 2.792e-06 0.33
CETP_HUMAN CETP Cholesteryl ester transfer protein 3.251e-06 0.34
FAK2_MOUSE Ptk2b Protein-tyrosine kinase 2-beta 4.256e-06 0.29
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 4.926e-06 0.34
LUCI_AQULA Luciferin 4-monooxygenase 6.433e-06 0.29
LCK_HUMAN LCK Tyrosine-protein kinase Lck 8.62e-06 0.39

ZINC1656944367

PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 2.103e-62 0.38
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 6.241e-61 0.36
CNOT7_HUMAN CNOT7 CCR4-NOT transcription complex subunit 7 1.226e-45 0.30
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 6.337e-45 0.36
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 4.428e-43 0.38
PHHY_PSEFL pobA p-hydroxybenzoate hydroxylase 2.707e-37 0.30
PMT1_CANAL PMT1 Dolichyl-phosphate-mannose--protein mannosyltransferase 1 1.773e-31 0.30
THYX_PBCV1 Probable flavin-dependent thymidylate synthase 2.298e-27 0.33
Q43014_PRUAV Beta-glucosidase 1.407e-26 0.33
HMOX1_HUMAN HMOX1 Heme oxygenase 1 1.62e-24 0.30
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 1.719e-24 0.36
Q6RY99_RAT Tetraspanin 1.007e-20 0.29
KDM5A_HUMAN KDM5A Lysine-specific demethylase 5A 1.075e-20 0.37
KDM5B_HUMAN KDM5B Lysine-specific demethylase 5B 8.986e-20 0.37
EBPL_HUMAN EBPL Emopamil-binding protein-like 3.691e-19 0.30
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 4.245e-19 0.35
HDAC7_HUMAN HDAC7 Histone deacetylase 7 4.796e-18 0.33
ACRO_PIG ACR Acrosin 1.484e-17 0.32
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 1.967e-17 0.37
Q5NGQ3_FRATT fabI Enoyl-[acyl-carrier-protein] reductase [NADH] 1.11e-16 0.42
ADA_HUMAN ADA Adenosine deaminase 5.551e-16 0.31
TF_HUMAN F3 Tissue factor 9.992e-16 0.32
KLK_PIG Glandular kallikrein 5.884e-15 0.32
ENTK_HUMAN TMPRSS15 Enteropeptidase 7.883e-15 0.32
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 8.549e-15 0.39
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 8.882e-15 0.30
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 1.243e-14 0.36
Q53I59_TRYCR PDEC Phosphodiesterase 2.064e-13 0.35
FA7_HUMAN F7 Coagulation factor VII 7.925e-13 0.32
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 4.633e-12 0.39
KDM2B_HUMAN KDM2B Lysine-specific demethylase 2B 5.655e-12 0.33
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 6.918e-12 0.35
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 7.083e-12 0.37
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 1.114e-11 0.39
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 1.537e-11 0.28
FA5_HUMAN F5 Coagulation factor V 7.43e-11 0.29
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.454e-10 0.30
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 2.356e-10 0.36
GALR2_RAT Galr2 Galanin receptor type 2 4.325e-10 0.29
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 4.708e-10 0.34
PAR14_HUMAN PARP14 Protein mono-ADP-ribosyltransferase PARP14 2.529e-09 0.35
O96214_PLAFA pk7 Protein kinase domain-containing protein 2.631e-09 0.29
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 4.387e-09 0.34
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 1.018e-08 0.29
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 1.093e-08 0.32
FABI_BACSU fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 2.18e-08 0.35
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 2.929e-08 0.29
HDA11_HUMAN HDAC11 Histone deacetylase 11 3.157e-08 0.32
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.205e-07 0.43
OPRD_HUMAN OPRD1 Delta-type opioid receptor 1.508e-07 0.38
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.215e-07 0.43
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.355e-07 0.32
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 5.554e-07 0.31
TRY1_HUMAN PRSS1 Trypsin-1 5.696e-07 0.32
NEK2_HUMAN NEK2 Serine/threonine-protein kinase Nek2 1.215e-06 0.31
KLK5_HUMAN KLK5 Kallikrein-5 1.241e-06 0.30
Q8WQX9_9TRYP PDEB1 Phosphodiesterase 4.287e-06 0.31
XDH_RAT Xdh Xanthine dehydrogenase/oxidase 8.822e-06 0.30
GRM5_HUMAN GRM5 Metabotropic glutamate receptor 5 9.258e-06 0.34
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 9.449e-06 0.31

ZINC78598572

F264_HUMAN PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 4.776e-61 0.42
AGTR1_BOVIN AGTR1 Type-1 angiotensin II receptor 2.542e-49 0.33
NADD_BACAC nadD Probable nicotinate-nucleotide adenylyltransferase 3.894e-48 0.30
ISPE_ECOLI ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 3.537e-46 0.37
RCOR3_HUMAN RCOR3 REST corepressor 3 2.644e-41 0.33
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 2.704e-37 0.33
GYRA_STAAU gyrA DNA gyrase subunit A 3.465e-37 0.46
PANK2_HUMAN PANK2 Pantothenate kinase 2, mitochondrial 1.457e-36 0.29
Q9FBC5_STREE fabK Enoyl-ACP reductase II 1.143e-35 0.35
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 7.497e-35 0.40
GRM5_MOUSE Grm5 Metabotropic glutamate receptor 5 8.366e-33 0.32
F263_HUMAN PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 6.289e-32 0.43
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.219e-29 0.30
GRB7_HUMAN GRB7 Growth factor receptor-bound protein 7 1.37e-28 0.36
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 2.206e-28 0.39
PANK3_HUMAN PANK3 Pantothenate kinase 3 5.183e-27 0.29
O31272_9GAMM imiS Beta-lactamase 8.125e-27 0.31
GASR_CANLF CCKBR Gastrin/cholecystokinin type B receptor 2.716e-25 0.42
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 7.466e-24 0.45
TSSK3_HUMAN TSSK3 Testis-specific serine/threonine-protein kinase 3 1.069e-23 0.29
TERT_HUMAN TERT Telomerase reverse transcriptase 1.323e-23 0.35
ENL_HUMAN MLLT1 Protein ENL 2.847e-23 0.29
HDAC3_HUMAN HDAC3 Histone deacetylase 3 2.905e-23 0.46
GYRB_STAAU gyrB DNA gyrase subunit B 3.756e-23 0.46
PANK1_HUMAN PANK1 Pantothenate kinase 1 7.815e-23 0.29
HPSE_HUMAN HPSE Heparanase 1.208e-22 0.38
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 7.435e-22 0.32
SHH_MOUSE Shh Sonic hedgehog protein 3.067e-21 0.44
Q7K6A1_PLAF7 Histone deacetylase 1.475e-20 0.33
LDLR_HUMAN LDLR Low-density lipoprotein receptor 1.922e-20 0.40
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.287e-19 0.35
CLTR1_CAVPO CYSLTR1 Cysteinyl leukotriene receptor 1 7.643e-19 0.37
TAU_RAT Mapt Microtubule-associated protein tau 3.72e-18 0.29
SYFA_HAEIN pheS Phenylalanine--tRNA ligase alpha subunit 1.006e-17 0.28
SYFA_STRPN pheS Phenylalanine--tRNA ligase alpha subunit 1.006e-17 0.28
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 2.104e-17 0.40
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 2.22e-16 0.38
HDAC6_HUMAN HDAC6 Histone deacetylase 6 3.331e-16 0.42
HDAC8_HUMAN HDAC8 Histone deacetylase 8 4.441e-16 0.40
HDAC2_HUMAN HDAC2 Histone deacetylase 2 5.551e-16 0.40
PAR12_HUMAN PARP12 Protein mono-ADP-ribosyltransferase PARP12 5.551e-16 0.30
SOAT1_MOUSE Soat1 Sterol O-acyltransferase 1 5.551e-16 0.37
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 3.22e-15 0.43
Q9ZTP8_MAIZE hd1b Histone deacetylase 4.33e-15 0.33
HDAC1_HUMAN HDAC1 Histone deacetylase 1 5.107e-15 0.46
CLTR1_HUMAN CYSLTR1 Cysteinyl leukotriene receptor 1 1.921e-14 0.45
CYSP_TRYCR Cruzipain 5.418e-14 0.41
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 9.981e-14 0.34
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 1.842e-13 0.42
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 5.25e-13 0.34
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 1.193e-12 0.33
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 1.685e-12 0.38
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 1.88e-12 0.30
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 2.039e-12 0.46
TNF11_MOUSE Tnfsf11 Tumor necrosis factor ligand superfamily member 11 5.659e-11 0.29
KISSR_HUMAN KISS1R KiSS-1 receptor 5.806e-11 0.31
HDAC9_HUMAN HDAC9 Histone deacetylase 9 6.292e-11 0.35
AGTR1_RABIT AGTR1 Type-1 angiotensin II receptor 1.127e-10 0.39
HDA11_HUMAN HDAC11 Histone deacetylase 11 1.162e-10 0.35
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 1.936e-10 0.30
KC1D_RAT Csnk1d Casein kinase I isoform delta 4.321e-10 0.39
AGTRB_RAT Agtr1b Type-1B angiotensin II receptor 4.693e-10 0.32
PARP4_HUMAN PARP4 Protein mono-ADP-ribosyltransferase PARP4 1.021e-09 0.30
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.2e-09 0.41
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 3.332e-09 0.33
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 5.6e-09 0.37
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 8.935e-09 0.33
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 2.493e-08 0.33
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 3.579e-08 0.32
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 4.756e-08 0.42
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 7.851e-08 0.40
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 9.243e-08 0.30
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 9.881e-08 0.29
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 1.172e-07 0.42
HDAC4_HUMAN HDAC4 Histone deacetylase 4 1.236e-07 0.40
ALKB3_HUMAN ALKBH3 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 1.592e-07 0.28
KLF5_HUMAN KLF5 Krueppel-like factor 5 3.662e-07 0.31
ACES_ELEEL ache Acetylcholinesterase 3.725e-07 0.36
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 4.755e-07 0.29
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 6.072e-07 0.31
AGTRA_RAT Agtr1 Type-1A angiotensin II receptor 7.381e-07 0.29
PRIO_MESAU PRNP Major prion protein 8.948e-07 0.31
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 9.384e-07 0.33
ALBU_HUMAN ALB Serum albumin 1.023e-06 0.28
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 1.241e-06 0.30
HDAC1_MOUSE Hdac1 Histone deacetylase 1 2.506e-06 0.33
A5H660_SCHMA HDAC8 Histone deacetylase 8 2.761e-06 0.33
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 2.849e-06 0.29
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 2.857e-06 0.40
DUS6_RAT Dusp6 Dual specificity protein phosphatase 6 3.605e-06 0.43
AAPK2_HUMAN PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 4.833e-06 0.38
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 5.327e-06 0.29
HDAC5_HUMAN HDAC5 Histone deacetylase 5 7.507e-06 0.35
HDAC7_HUMAN HDAC7 Histone deacetylase 7 7.67e-06 0.35

ZINC57559892

C3SLB7_ECOLX glmU Bifunctional protein GlmU 2.707e-58 0.35
NADD_BACAC nadD Probable nicotinate-nucleotide adenylyltransferase 1.112e-45 0.29
Q25615_ONCVO Chitinase 2.062e-38 0.34
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 8.937e-38 0.50
PGDA2_BACCR Peptidoglycan-N-acetylglucosamine deacetylase BC_1974 3.56e-37 0.29
PARP1_BOVIN PARP1 Poly [ADP-ribose] polymerase 1 5.83e-37 0.30
BCAT1_RAT Bcat1 Branched-chain-amino-acid aminotransferase, cytosolic 1.377e-35 0.28
BCAT2_RAT Bcat2 Branched-chain-amino-acid aminotransferase, mitochondrial 1.377e-35 0.28
BGLR_HUMAN GUSB Beta-glucuronidase 1.394e-34 0.38
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 1.76e-33 0.42
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 6.066e-33 0.38
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 4.488e-32 0.35
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 2.197e-31 0.34
GRM5_MOUSE Grm5 Metabotropic glutamate receptor 5 4.508e-29 0.29
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 6.129e-29 0.39
KPYK_STAAR pyk Pyruvate kinase 1.952e-28 0.44
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 6.771e-28 0.32
ANDR_MOUSE Ar Androgen receptor 1.547e-27 0.43
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 9.638e-27 0.45
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.076e-26 0.31
PRIO_SHEEP PRNP Major prion protein 1.418e-26 0.35
TGT_HUMAN QTRT1 Queuine tRNA-ribosyltransferase catalytic subunit 1 1.941e-26 0.33
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 2.67e-26 0.32
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 5.22e-26 0.42
CTNB1_HUMAN CTNNB1 Catenin beta-1 2.959e-24 0.32
LEF1_HUMAN LEF1 Lymphoid enhancer-binding factor 1 1.348e-23 0.29
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 4.822e-23 0.46
CFTR_HUMAN CFTR Cystic fibrosis transmembrane conductance regulator 5.549e-22 0.39
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 9.413e-22 0.36
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 3.367e-21 0.40
OXDD_HUMAN DDO D-aspartate oxidase 6.654e-21 0.33
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.777e-20 0.39
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 2.166e-20 0.29
CCKAR_RAT Cckar Cholecystokinin receptor type A 3.217e-20 0.39
SHH_MOUSE Shh Sonic hedgehog protein 5.04e-20 0.34
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 8.782e-20 0.32
BCAT1_HUMAN BCAT1 Branched-chain-amino-acid aminotransferase, cytosolic 1.048e-19 0.30
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 1.048e-19 0.31
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 1.1e-19 0.31
MYG_HUMAN MB Myoglobin 1.575e-19 0.38
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 4.828e-19 0.47
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 8.132e-19 0.32
PAR12_HUMAN PARP12 Protein mono-ADP-ribosyltransferase PARP12 1.224e-18 0.36
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 1.623e-18 0.32
EPHB_MYCTO Epoxide hydrolase B 1.858e-18 0.29
RXFP2_HUMAN RXFP2 Relaxin receptor 2 4.879e-18 0.29
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 9.382e-18 0.40
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 1.367e-17 0.29
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 2.969e-17 0.33
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 3.857e-17 0.33
SENP7_HUMAN SENP7 Sentrin-specific protease 7 5.551e-16 0.45
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 1.221e-15 0.53
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 1.554e-15 0.40
PA_I000X PA Polymerase acidic protein 3.22e-15 0.29
BXE_CLOBO botE Botulinum neurotoxin type E 3.775e-15 0.38
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 1.799e-14 0.36
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 1.921e-14 0.53
TYSY_CRYNB TMP1 Thymidylate synthase 1.954e-14 0.30
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 3.053e-14 0.45
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 1.985e-13 0.34
P2RY6_RAT P2ry6 P2Y purinoceptor 6 3.084e-13 0.29
SENP6_HUMAN SENP6 Sentrin-specific protease 6 8.405e-13 0.45
MAPK2_HUMAN MAPKAPK2 MAP kinase-activated protein kinase 2 1.451e-12 0.36
SENP8_HUMAN SENP8 Sentrin-specific protease 8 1.515e-12 0.45
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 1.735e-12 0.33
LUCI_AQULA Luciferin 4-monooxygenase 2.3e-12 0.35
PANC_MYCTU panC Pantothenate synthetase 2.456e-12 0.32
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 4.108e-12 0.36
Q38C41_TRYB2 Phosphotransferase 7.534e-12 0.32
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 2.367e-11 0.40
PARP4_HUMAN PARP4 Protein mono-ADP-ribosyltransferase PARP4 2.884e-11 0.36
AURKA_HUMAN AURKA Aurora kinase A 3.907e-11 0.42
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 5.504e-11 0.29
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 5.958e-11 0.31
CASP3_HUMAN CASP3 Caspase-3 6.365e-11 0.45
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 7.25e-11 0.32
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 8.547e-11 0.40
PDGFB_HUMAN PDGFB Platelet-derived growth factor subunit B 1.304e-10 0.30
SCAF_HCMVA UL80 Capsid scaffolding protein 2.3e-10 0.31
TYSY_ECOLI thyA Thymidylate synthase 2.455e-10 0.32
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 3.086e-10 0.40
UROK_HUMAN PLAU Urokinase-type plasminogen activator 3.154e-10 0.36
HSP12_CAEEL hsp-16.2 Heat shock protein Hsp-16.2 3.807e-10 0.30
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 1.13e-09 0.35
C3SLN3_ECOLX gyrB DNA gyrase subunit B 1.93e-09 0.30
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 1.983e-09 0.32
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 2.922e-09 0.39
NR1H4_HUMAN NR1H4 Bile acid receptor 2.963e-09 0.37
O77078_PLAFA fabH Beta-ketoacyl-acyl carrier protein synthase III 3.025e-09 0.31
DLDH_MYCTU lpdC Dihydrolipoyl dehydrogenase 3.199e-09 0.41
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 3.251e-09 0.36
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 4.226e-09 0.28
PARP2_HUMAN PARP2 Poly [ADP-ribose] polymerase 2 6.799e-09 0.37
HPSE_HUMAN HPSE Heparanase 6.9e-09 0.33
RCOR1_HUMAN RCOR1 REST corepressor 1 1.543e-08 0.45
AURKB_HUMAN AURKB Aurora kinase B 1.75e-08 0.42
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 2.026e-08 0.29
TPA_HUMAN PLAT Tissue-type plasminogen activator 2.137e-08 0.35
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 2.515e-08 0.29
KAPCA_BOVIN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 2.564e-08 0.30
TPOR_HUMAN MPL Thrombopoietin receptor 2.571e-08 0.30
OXDA_RAT Dao D-amino-acid oxidase 2.709e-08 0.33
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 3.028e-08 0.34
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 3.289e-08 0.35
STXA_SHIDY stxA Shiga toxin subunit A 3.386e-08 0.29
Q76353_9HIV1 Integrase 3.658e-08 0.37
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 4.048e-08 0.45
RXFP1_HUMAN RXFP1 Relaxin receptor 1 4.765e-08 0.35
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 5.003e-08 0.45
CASP6_HUMAN CASP6 Caspase-6 9.522e-08 0.45
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 1.188e-07 0.31
KLK1_HUMAN KLK1 Kallikrein-1 1.272e-07 0.31
RECA_MYCTU recA Protein RecA 1.463e-07 0.45
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 1.791e-07 0.47
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.838e-07 0.33
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 1.941e-07 0.33
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 2.148e-07 0.35
TRYP_PIG Trypsin 2.883e-07 0.31
A3KMY8_BOVIN GUSB Beta-glucuronidase 3.344e-07 0.31
KLF5_HUMAN KLF5 Krueppel-like factor 5 3.532e-07 0.33
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 4.192e-07 0.31
EGFR_MOUSE Egfr Epidermal growth factor receptor 5.533e-07 0.28
CASP9_HUMAN CASP9 Caspase-9 6.138e-07 0.45
MMP13_BOVIN MMP13 Collagenase 3 7.272e-07 0.39
MAPK3_HUMAN MAPKAPK3 MAP kinase-activated protein kinase 3 7.827e-07 0.30
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 8.257e-07 0.36
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 8.279e-07 0.31
FA10_HUMAN F10 Coagulation factor X 9.45e-07 0.40
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.005e-06 0.31
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 1.231e-06 0.36
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 1.231e-06 0.36
PLEC_HUMAN PLEC Plectin 1.363e-06 0.37
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 2.26e-06 0.29
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.558e-06 0.29
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 2.66e-06 0.34
LDLR_HUMAN LDLR Low-density lipoprotein receptor 2.849e-06 0.29
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 3.148e-06 0.44
TOP1_HUMAN TOP1 DNA topoisomerase 1 3.315e-06 0.34
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 3.495e-06 0.31
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 3.573e-06 0.36
SIK1_HUMAN SIK1 Serine/threonine-protein kinase SIK1 3.753e-06 0.42
TOP3_BACSU topB DNA topoisomerase 3 4.084e-06 0.29
LUCI_PHOPY Luciferin 4-monooxygenase 4.389e-06 0.32
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 4.641e-06 0.47
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 7.112e-06 0.29
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 7.241e-06 0.31
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 8.899e-06 0.31

ZINC1602307355

AHR_MOUSE Ahr Aryl hydrocarbon receptor 8.186e-58 0.34
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 1.293e-39 0.33
BAP1_HUMAN BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1 6.705e-36 0.28
LUCI_PHOPE Luciferin 4-monooxygenase 1.376e-32 0.33
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 2.21e-25 0.34
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 2.112e-20 0.34
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 3.063e-20 0.34
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 6.661e-16 0.33
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 1.221e-15 0.33
LUCI_PHOPY Luciferin 4-monooxygenase 2.22e-15 0.45
MMP13_MOUSE Mmp13 Collagenase 3 2.554e-15 0.33
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 1.187e-13 0.34
PLD2_HUMAN PLD2 Phospholipase D2 1.632e-13 0.33
PLD1_HUMAN PLD1 Phospholipase D1 3.358e-13 0.33
GSTP1_HUMAN GSTP1 Glutathione S-transferase P 3.384e-13 0.33
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 5.663e-13 0.33
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.621e-12 0.39
SKN1_CAEEL skn-1 Protein skinhead-1 1.998e-11 0.38
SYPC_CANAX PRS Proline--tRNA ligase, cytoplasmic 4.006e-11 0.34
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 1.304e-09 0.34
GRM5_HUMAN GRM5 Metabotropic glutamate receptor 5 5.276e-09 0.32
PK3CA_MOUSE Pik3ca Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 1.291e-08 0.30
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 9.132e-08 0.29
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 1.621e-07 0.35
P3C2A_HUMAN PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 2.869e-07 0.28
HDAC4_HUMAN HDAC4 Histone deacetylase 4 2.968e-07 0.34
NR4A2_HUMAN NR4A2 Nuclear receptor subfamily 4 group A member 2 4.339e-07 0.29
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 5.213e-07 0.32
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 6.219e-07 0.32
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 7.44e-07 0.35
KS6B2_HUMAN RPS6KB2 Ribosomal protein S6 kinase beta-2 1.198e-06 0.28
KLF5_HUMAN KLF5 Krueppel-like factor 5 3.137e-06 0.36
KC1G2_HUMAN CSNK1G2 Casein kinase I isoform gamma-2 3.852e-06 0.43
SENP7_HUMAN SENP7 Sentrin-specific protease 7 4.955e-06 0.40
BIRC5_HUMAN BIRC5 Baculoviral IAP repeat-containing protein 5 6.061e-06 0.38
SENP8_HUMAN SENP8 Sentrin-specific protease 8 7.466e-06 0.40
DPOL_VACCW POL DNA polymerase 8.755e-06 0.28
SENP6_HUMAN SENP6 Sentrin-specific protease 6 8.757e-06 0.40

ZINC325102010

PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 1.927e-56 0.39
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 1.048e-49 0.38
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 2.427e-37 0.30
ACHA7_MACMU CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 2.095e-36 0.29
PAR16_HUMAN PARP16 Protein mono-ADP-ribosyltransferase PARP16 4.783e-31 0.32
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 2.712e-23 0.32
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 1.404e-21 0.32
PAR14_HUMAN PARP14 Protein mono-ADP-ribosyltransferase PARP14 7.231e-21 0.31
PARP6_HUMAN PARP6 Protein mono-ADP-ribosyltransferase PARP6 2.318e-20 0.32
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 4.43e-19 0.30
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 1.015e-17 0.34
A5H660_SCHMA HDAC8 Histone deacetylase 8 1.11e-16 0.43
MP2K7_HUMAN MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 1.11e-16 0.31
STXA_SHIDY stxA Shiga toxin subunit A 4.441e-16 0.32
PAR12_HUMAN PARP12 Protein mono-ADP-ribosyltransferase PARP12 7.105e-15 0.28
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 1.177e-14 0.30
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.354e-14 0.35
HDAC1_HUMAN HDAC1 Histone deacetylase 1 6.617e-14 0.37
Q5NGQ3_FRATT fabI Enoyl-[acyl-carrier-protein] reductase [NADH] 1.463e-13 0.33
AURKA_HUMAN AURKA Aurora kinase A 4.221e-13 0.39
AURKB_HUMAN AURKB Aurora kinase B 1.049e-11 0.39
HDAC1_MOUSE Hdac1 Histone deacetylase 1 1.941e-11 0.29
HDAC2_HUMAN HDAC2 Histone deacetylase 2 8.203e-11 0.32
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.46e-10 0.31
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 2.542e-10 0.32
PARP4_HUMAN PARP4 Protein mono-ADP-ribosyltransferase PARP4 2.649e-10 0.32
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 6.384e-10 0.40
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 6.463e-10 0.32
STIM1_RAT Stim1 Stromal interaction molecule 1 6.578e-10 0.30
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 5.223e-09 0.32
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 5.437e-09 0.42
ST32B_HUMAN STK32B Serine/threonine-protein kinase 32B 6.365e-09 0.30
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 9.029e-09 0.32
PARP2_HUMAN PARP2 Poly [ADP-ribose] polymerase 2 9.681e-09 0.37
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 1.096e-08 0.35
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 1.536e-08 0.28
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 1.718e-08 0.38
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 2.184e-08 0.35
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 4.239e-08 0.30
DHB14_HUMAN HSD17B14 17-beta-hydroxysteroid dehydrogenase 14 4.255e-08 0.29
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 5.247e-08 0.32
STIM1_HUMAN STIM1 Stromal interaction molecule 1 6.159e-08 0.30
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 7.169e-08 0.30
RXFP1_HUMAN RXFP1 Relaxin receptor 1 7.485e-08 0.32
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 1.276e-07 0.30
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 1.276e-07 0.30
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 1.276e-07 0.30
MYO3B_HUMAN MYO3B Myosin-IIIb 1.276e-07 0.30
ST32A_HUMAN STK32A Serine/threonine-protein kinase 32A 1.276e-07 0.30
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 1.348e-07 0.36
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 2.209e-07 0.36
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 2.585e-07 0.30
CRCM1_HUMAN ORAI1 Calcium release-activated calcium channel protein 1 3.117e-07 0.30
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 3.884e-07 0.36
PYRD_RAT Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 3.932e-07 0.34
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 5.552e-07 0.35
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 9.835e-07 0.30
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 9.835e-07 0.30
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 9.835e-07 0.30
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 1.094e-06 0.32
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 1.467e-06 0.36
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.58e-06 0.34
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 1.592e-06 0.36
BRSK1_HUMAN BRSK1 Serine/threonine-protein kinase BRSK1 2.192e-06 0.35
CRCM1_RAT Orai1 Calcium release-activated calcium channel protein 1 2.21e-06 0.30
KCC2B_HUMAN CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta 2.917e-06 0.32
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 3.046e-06 0.41
NEUR3_HUMAN NEU3 Sialidase-3 3.168e-06 0.28
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 3.329e-06 0.31
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 3.848e-06 0.36
INSRR_HUMAN INSRR Insulin receptor-related protein 4.4e-06 0.30
KCC2G_HUMAN CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 4.756e-06 0.32
ST17A_HUMAN STK17A Serine/threonine-protein kinase 17A 6.663e-06 0.36
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 6.674e-06 0.30
PAG_BACAN pagA Protective antigen 8.86e-06 0.35
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 9.272e-06 0.35
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 9.725e-06 0.40

ZINC47290313

BGLR_HUMAN GUSB Beta-glucuronidase 1.017e-55 0.45
ISPE_ECOLI ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 2.649e-45 0.36
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 4.98e-41 0.41
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 1.324e-39 0.58
TYTR_CRIFA TPR Trypanothione reductase 6.694e-38 0.30
SPRE_HUMAN SPR Sepiapterin reductase 1.394e-36 0.31
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 3.059e-36 0.52
TCMO_HELTU CYP73A1 Trans-cinnamate 4-monooxygenase 8.333e-36 0.28
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 7.437e-34 0.40
TYTR_TRYCR TPR Trypanothione reductase 1.693e-33 0.37
TGT_HUMAN QTRT1 Queuine tRNA-ribosyltransferase catalytic subunit 1 7.094e-33 0.41
ACES_TETCF ache Acetylcholinesterase 1.073e-27 0.32
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 1.276e-25 0.33
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 2.842e-25 0.62
RNH1_HUMAN RNASEH1 Ribonuclease H1 7.479e-23 0.37
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 9.809e-23 0.52
CHLE_HUMAN BCHE Cholinesterase 3.344e-20 0.40
ACES_BOVIN ACHE Acetylcholinesterase 1.657e-19 0.40
SYM_STAAW metG Methionine--tRNA ligase 8.372e-18 0.33
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 1.11e-16 0.30
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 2.22e-16 0.36
MMP10_HUMAN MMP10 Stromelysin-2 1.221e-15 0.34
A3KMY8_BOVIN GUSB Beta-glucuronidase 2.665e-15 0.35
CYSP_TRYCR Cruzipain 4.441e-15 0.44
PA_I000X PA Polymerase acidic protein 7.438e-15 0.28
ACES_HUMAN ACHE Acetylcholinesterase 8.438e-15 0.40
NMBR_HUMAN NMBR Neuromedin-B receptor 1.01e-14 0.31
PERM_HUMAN MPO Myeloperoxidase 4.208e-14 0.35
PARP2_HUMAN PARP2 Poly [ADP-ribose] polymerase 2 7.172e-14 0.62
MTR1C_XENLA mtnr1c Melatonin receptor type 1C 9.792e-14 0.33
BODG_PSESK Gamma-butyrobetaine dioxygenase 4.967e-13 0.28
WNT3A_HUMAN WNT3A Protein Wnt-3a 8.897e-13 0.40
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 2.811e-12 0.37
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 4.887e-12 0.38
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 4.887e-12 0.38
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 1.18e-11 0.36
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 1.196e-11 0.28
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.403e-11 0.43
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 2.999e-11 0.40
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 8.798e-11 0.38
PRIO_MESAU PRNP Major prion protein 1.417e-10 0.51
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 4.41e-10 0.35
CHLE_HORSE BCHE Cholinesterase 2.212e-09 0.33
ERM_STREE erm rRNA adenine N-6-methyltransferase 2.851e-09 0.29
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 4.722e-09 0.32
AMP1_PLAFQ M1 family aminopeptidase 1.965e-08 0.31
ACES_ELEEL ache Acetylcholinesterase 3.187e-08 0.33
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 4.582e-08 0.38
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 7.14e-08 0.35
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 9.105e-08 0.34
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.063e-07 0.35
EGFR_MOUSE Egfr Epidermal growth factor receptor 1.206e-07 0.31
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 1.229e-07 0.47
PANK3_HUMAN PANK3 Pantothenate kinase 3 2.362e-07 0.29
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 3.081e-07 0.33
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 5.464e-07 0.28
LUCI_AQULA Luciferin 4-monooxygenase 6.132e-07 0.34
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 7.58e-07 0.34
MMP13_HUMAN MMP13 Collagenase 3 8.416e-07 0.36
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 1.101e-06 0.29
MMP8_HUMAN MMP8 Neutrophil collagenase 1.176e-06 0.34
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 1.51e-06 0.33
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 4.596e-06 0.29
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 5.641e-06 0.36
CASP1_HUMAN CASP1 Caspase-1 6.105e-06 0.35
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 6.156e-06 0.31
GRIA4_RAT Gria4 Glutamate receptor 4 6.739e-06 0.32
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 7.112e-06 0.29
PCNA_HUMAN PCNA Proliferating cell nuclear antigen 8.152e-06 0.29
MEX5_CAEEL mex-5 Zinc finger protein mex-5 8.565e-06 0.32

ZINC1595301214

SUCR1_HUMAN SUCNR1 Succinate receptor 1 2.671e-55 0.33
SUCR1_RAT Sucnr1 Succinate receptor 1 6.576e-46 0.30
OXGR1_HUMAN OXGR1 2-oxoglutarate receptor 1 4.054e-36 0.30
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 2.112e-25 0.32
Q9ZTP8_MAIZE hd1b Histone deacetylase 5.999e-21 0.31
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 2.998e-15 0.34
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 3.031e-12 0.32
PA2GC_HUMAN PLA2G2C Putative inactive group IIC secretory phospholipase A2 3.49e-12 0.36
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 1.468e-11 0.35
ITPR1_HUMAN ITPR1 Inositol 1,4,5-trisphosphate receptor type 1 1.537e-11 0.28
HDAC1_RAT Hdac1 Histone deacetylase 1 1.818e-11 0.29
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 5.482e-11 0.30
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 2.204e-10 0.31
CP74A_ARATH CYP74A Allene oxide synthase, chloroplastic 2.923e-10 0.30
TPH1_RAT Tph1 Tryptophan 5-hydroxylase 1 2.923e-10 0.30
TPH1_HUMAN TPH1 Tryptophan 5-hydroxylase 1 8.324e-10 0.30
MEP50_HUMAN WDR77 Methylosome protein 50 2.572e-09 0.32
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 3.207e-09 0.32
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 5.335e-08 0.35
UR2R_HUMAN UTS2R Urotensin-2 receptor 8.145e-08 0.36
PPAP_HUMAN ACP3 Prostatic acid phosphatase 1.324e-07 0.28
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 3.386e-07 0.31
Q6UB75_PIG Group VII phospholipase A2 5.904e-07 0.28
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 1.016e-06 0.32
PLM2_PLAFA Plasmepsin-2 1.345e-06 0.31
IDE_HUMAN IDE Insulin-degrading enzyme 3.404e-06 0.28
CATD_HUMAN CTSD Cathepsin D 6.373e-06 0.31
ANM3_HUMAN PRMT3 Protein arginine N-methyltransferase 3 8.966e-06 0.32
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 9.449e-06 0.31

ZINC432194222

Q56D28_CAVPO CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells 6.843e-53 0.35
GLUT4_RAT Slc2a4 Solute carrier family 2, facilitated glucose transporter member 4 3.104e-39 0.31
GTR8_HUMAN SLC2A8 Solute carrier family 2, facilitated glucose transporter member 8 3.104e-39 0.31
Q6RY99_RAT Tetraspanin 5.489e-27 0.40
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 7.024e-21 0.36
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 1.507e-19 0.31
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 2.22e-16 0.33
ADA_HUMAN ADA Adenosine deaminase 4.884e-13 0.31
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 1.453e-10 0.33
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 2.624e-10 0.33
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 1.356e-08 0.34
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 2.722e-08 0.31
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 2.799e-08 0.39
CRTM_STAAU crtM 4,4'-diapophytoene synthase 1.994e-07 0.31
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 3.269e-07 0.39
PDS_SYNE7 pds 15-cis-phytoene desaturase 5.653e-07 0.33
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 1.046e-06 0.31
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 4.939e-06 0.32
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 9.348e-06 0.30

ZINC654211310

ACES_TETCF ache Acetylcholinesterase 6.724e-52 0.35
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 6.285e-44 0.35
NCS1_HUMAN NCS1 Neuronal calcium sensor 1 1.377e-35 0.28
Q9VWX8_DROME Frq2 FI18190p1 1.377e-35 0.28
CHLE_HUMAN BCHE Cholinesterase 1.767e-33 0.35
ACES_HUMAN ACHE Acetylcholinesterase 3.99e-25 0.35
CHLE_HORSE BCHE Cholinesterase 1.351e-23 0.35
ACES_ELEEL ache Acetylcholinesterase 8.698e-21 0.35
ACES_BOVIN ACHE Acetylcholinesterase 1.007e-19 0.33
Q9JKC1_RAT Bche Carboxylic ester hydrolase 3.906e-19 0.32
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 1.319e-18 0.32
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 9.105e-18 0.32
DPO3_STAAU polC DNA polymerase III PolC-type 1.11e-16 0.30
RORG_MOUSE Rorc Nuclear receptor ROR-gamma 1.221e-15 0.33
PRIO_MESAU PRNP Major prion protein 2.809e-14 0.36
PRIO_HUMAN PRNP Major prion protein 4.334e-13 0.35
ACES_RAT Ache Acetylcholinesterase 2.823e-12 0.32
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 1.275e-10 0.32
PANK1_HUMAN PANK1 Pantothenate kinase 1 3.985e-08 0.29
A4_HUMAN APP Amyloid-beta precursor protein 7.174e-08 0.35
ITB8_HUMAN ITGB8 Integrin beta-8 7.37e-07 0.29
LUCI_AQULA Luciferin 4-monooxygenase 2.561e-06 0.31
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 5.823e-06 0.36

ZINC1607713173

VIPR2_HUMAN VIPR2 Vasoactive intestinal polypeptide receptor 2 2.651e-49 0.32
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 1.889e-34 0.40
OGT1_HUMAN OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 1.537e-18 0.33
SYT_YERPE thrS Threonine--tRNA ligase 3.331e-16 0.29
ADA33_HUMAN ADAM33 Disintegrin and metalloproteinase domain-containing protein 33 3.109e-15 0.30
BCAT1_HUMAN BCAT1 Branched-chain-amino-acid aminotransferase, cytosolic 2.931e-14 0.31
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 3.301e-12 0.32
HMDH_RAT Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 5.069e-11 0.31
SYTC_HUMAN TARS1 Threonine--tRNA ligase 1, cytoplasmic 5.09e-11 0.29
CASP3_HUMAN CASP3 Caspase-3 6.303e-11 0.34
FA10_BOVIN F10 Coagulation factor X 9.042e-10 0.30
NEK1_HUMAN NEK1 Serine/threonine-protein kinase Nek1 6.75e-09 0.32
MEP1B_HUMAN MEP1B Meprin A subunit beta 1.834e-08 0.29
MMP10_HUMAN MMP10 Stromelysin-2 2.174e-08 0.31
MMP7_HUMAN MMP7 Matrilysin 1.519e-07 0.31
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 1.812e-07 0.34
ADAM9_HUMAN ADAM9 Disintegrin and metalloproteinase domain-containing protein 9 4.119e-07 0.29
NPY5R_MOUSE Npy5r Neuropeptide Y receptor type 5 5.963e-07 0.36
B2LUN4_PIG GSK3-beta Glycogen synthase kinase 3 beta 3.203e-06 0.29
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 6.219e-06 0.29
CAN1_RAT Capn1 Calpain-1 catalytic subunit 6.558e-06 0.29
HRH3_CAVPO HRH3 Histamine H3 receptor 9.555e-06 0.30

ZINC1606832925

MMP13_MOUSE Mmp13 Collagenase 3 2.776e-47 0.33
NAMPT_RAT Nampt Nicotinamide phosphoribosyltransferase 5.988e-47 0.31
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.562e-37 0.37
SENP2_HUMAN SENP2 Sentrin-specific protease 2 2.223e-37 0.30
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.378e-36 0.34
QPCTL_HUMAN QPCTL Glutaminyl-peptide cyclotransferase-like protein 1.014e-35 0.35
E2AK3_RAT Eif2ak3 Eukaryotic translation initiation factor 2-alpha kinase 3 1.215e-35 0.28
VE1_HPV11 E1 Replication protein E1 1.245e-34 0.36
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 1.488e-32 0.42
FOLC_MOUSE Fpgs Folylpolyglutamate synthase, mitochondrial 2.623e-32 0.37
QPCT_HUMAN QPCT Glutaminyl-peptide cyclotransferase 5.035e-30 0.41
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 5.742e-28 0.37
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 2.818e-23 0.37
SCN3A_HUMAN SCN3A Sodium channel protein type 3 subunit alpha 2.052e-22 0.32
RFA1_HUMAN RPA1 Replication protein A 70 kDa DNA-binding subunit 1.013e-19 0.32
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 5.36e-19 0.35
NR1H4_HUMAN NR1H4 Bile acid receptor 3.092e-18 0.60
STABP_HUMAN STAMBP STAM-binding protein 4.441e-16 0.30
DYR_ENTFC folA Dihydrofolate reductase 1.61e-14 0.30
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 5.751e-14 0.45
IF4E_HUMAN EIF4E Eukaryotic translation initiation factor 4E 8.327e-14 0.34
TYSY_MOUSE Tyms Thymidylate synthase 9.026e-14 0.31
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 2.688e-13 0.36
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 7.064e-13 0.29
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 1.393e-12 0.31
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 4.194e-12 0.36
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 4.809e-12 0.32
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 5.629e-12 0.48
FOLC_HUMAN FPGS Folylpolyglutamate synthase, mitochondrial 2.627e-11 0.31
PTGES_CANLF PTGES Prostaglandin E synthase 4.959e-11 0.30
PA_I34A1 PA Polymerase acidic protein 1.977e-10 0.31
SYUA_HUMAN SNCA Alpha-synuclein 3.524e-10 0.31
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 4.905e-10 0.35
ALDH2_HUMAN ALDH2 Aldehyde dehydrogenase, mitochondrial 9.382e-10 0.30
MMP13_HUMAN MMP13 Collagenase 3 1.054e-09 0.36
GASR_BOVIN CCKBR Gastrin/cholecystokinin type B receptor 1.56e-09 0.32
ARBK1_HUMAN GRK2 Beta-adrenergic receptor kinase 1 2.77e-09 0.32
HDAC1_HUMAN HDAC1 Histone deacetylase 1 3.826e-09 0.44
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 4.244e-09 0.30
AGTR1_HUMAN AGTR1 Type-1 angiotensin II receptor 5.621e-09 0.32
ARBK2_HUMAN GRK3 Beta-adrenergic receptor kinase 2 6.127e-09 0.32
CAH2_BOVIN CA2 Carbonic anhydrase 2 7.414e-09 0.36
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 9.266e-09 0.29
HDAC2_HUMAN HDAC2 Histone deacetylase 2 9.556e-09 0.38
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 1.493e-08 0.28
CTNB1_HUMAN CTNNB1 Catenin beta-1 2.155e-08 0.30
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 2.94e-08 0.34
SCNAA_HUMAN SCN10A Sodium channel protein type 10 subunit alpha 3.029e-08 0.35
LUCI_RENRE Coelenterazine h 2-monooxygenase 4.521e-08 0.28
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 7.566e-08 0.30
KDM2B_HUMAN KDM2B Lysine-specific demethylase 2B 1.813e-07 0.31
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 2.164e-07 0.36
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 2.294e-07 0.36
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 2.729e-07 0.30
HDAC5_HUMAN HDAC5 Histone deacetylase 5 3.943e-07 0.32
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 6.546e-07 0.38
HDAC3_HUMAN HDAC3 Histone deacetylase 3 9.503e-07 0.38
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 9.93e-07 0.32
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.372e-06 0.44
LYOX_HUMAN LOX Protein-lysine 6-oxidase 2.106e-06 0.32
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 6.085e-06 0.35
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 9.098e-06 0.35
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 9.159e-06 0.32

ZINC26963777

SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 4.994e-47 0.31
DPO3_STAAU polC DNA polymerase III PolC-type 4e-46 0.36
ISPE_ECOLI ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 4.538e-44 0.35
CACB3_RAT Cacnb3 Voltage-dependent L-type calcium channel subunit beta-3 6.446e-43 0.34
NMDZ1_MOUSE Grin1 Glutamate receptor ionotropic, NMDA 1 1.361e-42 0.34
ITB8_HUMAN ITGB8 Integrin beta-8 2.582e-42 0.32
KCNN3_RAT Kcnn3 Small conductance calcium-activated potassium channel protein 3 5.029e-39 0.37
Q9FBC5_STREE fabK Enoyl-ACP reductase II 2.664e-37 0.38
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 2.414e-35 0.35
MEP50_HUMAN WDR77 Methylosome protein 50 9.67e-35 0.35
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 2.17e-34 0.35
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 3.778e-32 0.34
ITB5_HUMAN ITGB5 Integrin beta-5 3.961e-32 0.32
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 4.067e-31 0.36
GRM5_MOUSE Grm5 Metabotropic glutamate receptor 5 7.996e-31 0.30
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 3.562e-29 0.35
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 1.52e-28 0.35
ITAV_HUMAN ITGAV Integrin alpha-V 1.543e-27 0.40
PTGES_MOUSE Ptges Prostaglandin E synthase 2.994e-27 0.31
DGAT1_RAT Dgat1 Diacylglycerol O-acyltransferase 1 1.209e-25 0.31
ITB6_HUMAN ITGB6 Integrin beta-6 3.96e-24 0.32
CYSP_TRYCR Cruzipain 5.338e-24 0.74
TSSK3_HUMAN TSSK3 Testis-specific serine/threonine-protein kinase 3 1.069e-23 0.29
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 3.306e-23 0.39
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.675e-22 0.40
CAC1H_HUMAN CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H 1.367e-21 0.34
ACES_BOVIN ACHE Acetylcholinesterase 1.443e-21 0.34
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 2.584e-21 0.36
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 3.725e-20 0.36
SYFA_HAEIN pheS Phenylalanine--tRNA ligase alpha subunit 1.126e-18 0.30
SYFA_STRPN pheS Phenylalanine--tRNA ligase alpha subunit 1.126e-18 0.30
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 1.86e-18 0.32
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 2.878e-18 0.30
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 5.342e-18 0.36
ITB3_HUMAN ITGB3 Integrin beta-3 3.069e-17 0.40
ACOX1_RAT Acox1 Peroxisomal acyl-coenzyme A oxidase 1 4.77e-17 0.35
PDE10_HUMAN PDE10A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 1.11e-16 0.41
SPRE_HUMAN SPR Sepiapterin reductase 9.992e-16 0.32
ISPD_ARATH ISPD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic 1.887e-15 0.29
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 2.776e-15 0.29
Q5NGQ3_FRATT fabI Enoyl-[acyl-carrier-protein] reductase [NADH] 4.086e-14 0.35
DEF_MYCTU def Peptide deformylase 1.957e-13 0.30
MTR1B_CHICK Melatonin receptor type 1B 3.146e-13 0.29
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 3.645e-13 0.38
SOAT1_MOUSE Soat1 Sterol O-acyltransferase 1 4.421e-13 0.29
PRIO_MESAU PRNP Major prion protein 4.665e-13 0.35
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 4.994e-13 0.30
ACES_TETCF ache Acetylcholinesterase 7.38e-13 0.30
SCNNA_MOUSE Scnn1a Amiloride-sensitive sodium channel subunit alpha 3.325e-12 0.30
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 4.239e-12 0.34
CHLE_HUMAN BCHE Cholinesterase 6.989e-12 0.34
KCNN3_HUMAN KCNN3 Small conductance calcium-activated potassium channel protein 3 3.11e-11 0.31
ACES_ELEEL ache Acetylcholinesterase 5.992e-11 0.34
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 6.766e-11 0.34
KCNN1_HUMAN KCNN1 Small conductance calcium-activated potassium channel protein 1 7.039e-10 0.31
KLF5_HUMAN KLF5 Krueppel-like factor 5 3.029e-09 0.38
CHLE_HORSE BCHE Cholinesterase 4.742e-09 0.34
SCN4A_RAT Scn4a Sodium channel protein type 4 subunit alpha 4.756e-09 0.34
ACES_HUMAN ACHE Acetylcholinesterase 5.461e-09 0.34
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 7.357e-09 0.30
SHH_MOUSE Shh Sonic hedgehog protein 7.541e-09 0.31
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 1.519e-08 0.38
PEBB_HUMAN CBFB Core-binding factor subunit beta 2.085e-08 0.31
KCNN2_HUMAN KCNN2 Small conductance calcium-activated potassium channel protein 2 2.668e-08 0.31
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 1.27e-07 0.30
Q8IL11_PLAF7 M17 leucyl aminopeptidase 2.056e-07 0.35
CRTM_STAAU crtM 4,4'-diapophytoene synthase 2.683e-07 0.30
LDLR_HUMAN LDLR Low-density lipoprotein receptor 5.015e-07 0.32
ETHR_MYCTU ethR HTH-type transcriptional regulator EthR 5.113e-07 0.30
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 5.944e-07 0.30
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 7.955e-07 0.29
AA1R_RAT Adora1 Adenosine receptor A1 8.982e-07 0.34
SCRB1_HUMAN SCARB1 Scavenger receptor class B member 1 1.097e-06 0.34
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 1.224e-06 0.31
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 1.241e-06 0.30
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.399e-06 0.34
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 1.441e-06 0.36
GYRA_STAAU gyrA DNA gyrase subunit A 1.749e-06 0.33
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 1.845e-06 0.30
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 2.147e-06 0.33
TOP3_BACSU topB DNA topoisomerase 3 2.845e-06 0.30
VGFR2_MOUSE Kdr Vascular endothelial growth factor receptor 2 3.505e-06 0.29
CLTR1_CAVPO CYSLTR1 Cysteinyl leukotriene receptor 1 5.91e-06 0.32
Q9BHT9_PLABE G6PD-6PGL Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 7.159e-06 0.32
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 8.815e-06 0.31
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 9.938e-06 0.36

ZINC1645129342

NADD_BACAC nadD Probable nicotinate-nucleotide adenylyltransferase 1.743e-46 0.30
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 1.635e-39 0.38
PANK2_HUMAN PANK2 Pantothenate kinase 2, mitochondrial 2.333e-36 0.29
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 1.058e-32 0.33
TERT_HUMAN TERT Telomerase reverse transcriptase 8.55e-29 0.37
UT1_RAT Slc14a1 Urea transporter 1 3.228e-20 0.28
PANK1_HUMAN PANK1 Pantothenate kinase 1 1.11e-16 0.33
PANK3_HUMAN PANK3 Pantothenate kinase 3 5.551e-15 0.33
PAR12_HUMAN PARP12 Protein mono-ADP-ribosyltransferase PARP12 5.662e-15 0.28
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 5.884e-15 0.58
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 7.372e-14 0.34
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 2.083e-12 0.32
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 5.157e-12 0.30
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 1.17e-11 0.28
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 1.192e-11 0.30
CASP2_HUMAN CASP2 Caspase-2 1.573e-11 0.30
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 3.849e-11 0.32
ELOV6_HUMAN ELOVL6 Elongation of very long chain fatty acids protein 6 7.642e-11 0.30
CNR2_RAT Cnr2 Cannabinoid receptor 2 5.267e-10 0.36
ELOV6_MOUSE Elovl6 Elongation of very long chain fatty acids protein 6 8.682e-10 0.28
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 8.811e-10 0.28
PARP4_HUMAN PARP4 Protein mono-ADP-ribosyltransferase PARP4 4.155e-09 0.28
GYRA_STAAU gyrA DNA gyrase subunit A 1.128e-08 0.33
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 1.822e-08 0.34
ITA3_HUMAN ITGA3 Integrin alpha-3 1.828e-08 0.31
FUCO_BOVIN FUCA1 Tissue alpha-L-fucosidase 2.46e-08 0.30
SPRE_HUMAN SPR Sepiapterin reductase 5.037e-08 0.30
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.017e-07 0.36
Q38C41_TRYB2 Phosphotransferase 1.384e-07 0.32
GYRB_MYCS2 gyrB DNA gyrase subunit B 8.547e-07 0.29
PERM_HUMAN MPO Myeloperoxidase 8.941e-07 0.33
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 9.972e-07 0.38
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 2.369e-06 0.28
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 3.861e-06 0.38
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 4.987e-06 0.33
HDAC9_HUMAN HDAC9 Histone deacetylase 9 8.368e-06 0.33

ZINC1637782063

GLSL_MOUSE Gls2 Glutaminase liver isoform, mitochondrial 1.924e-46 0.37
PFKA_TRYBB pfk ATP-dependent 6-phosphofructokinase 2.971e-41 0.31
PFKA_TRYCC pfk ATP-dependent 6-phosphofructokinase 4.209e-40 0.31
UT1_RAT Slc14a1 Urea transporter 1 4.182e-31 0.31
GLSK_HUMAN GLS Glutaminase kidney isoform, mitochondrial 1.283e-26 0.39
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 1.52e-20 0.40
UT2_RAT Slc14a2 Urea transporter 2 1.11e-16 0.31
PAR12_HUMAN PARP12 Protein mono-ADP-ribosyltransferase PARP12 5.662e-15 0.28
PTR1_LEIMA PTR1 Pteridine reductase 1 2.501e-13 0.33
AKT1_MOUSE Akt1 RAC-alpha serine/threonine-protein kinase 2.833e-13 0.30
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 1.17e-11 0.28
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 8.811e-10 0.28
PARP4_HUMAN PARP4 Protein mono-ADP-ribosyltransferase PARP4 4.155e-09 0.28
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 2.733e-06 0.32
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 6.575e-06 0.33

ZINC1601627317

FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 6.062e-46 0.35
Q38C41_TRYB2 Phosphotransferase 6.514e-46 0.39
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 6.304e-45 0.39
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 2.376e-42 0.34
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 3.283e-40 0.36
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 3.4e-40 0.39
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 9.749e-40 0.32
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 3.384e-37 0.35
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 1.502e-34 0.32
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 2.616e-32 0.32
PYGL_RAT Pygl Glycogen phosphorylase, liver form 1.146e-29 0.32
NAMPT_RAT Nampt Nicotinamide phosphoribosyltransferase 5.245e-27 0.33
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 2.1e-25 0.39
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 2.585e-25 0.32
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 5.12e-25 0.39
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 6.236e-24 0.33
FABH_STAAM fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 8.657e-24 0.29
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 1.49e-21 0.32
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 1.473e-20 0.34
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 5.028e-20 0.34
LYOX_HUMAN LOX Protein-lysine 6-oxidase 5.061e-18 0.33
TRPC1_HUMAN TRPC1 Short transient receptor potential channel 1 8.52e-18 0.28
KCNQ2_RAT Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 9.523e-18 0.44
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 1.776e-17 0.42
FABH_STRP3 fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.109e-15 0.29
NR1H4_HUMAN NR1H4 Bile acid receptor 3.22e-15 0.37
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 7.661e-15 0.30
CXCR2_HUMAN CXCR2 C-X-C chemokine receptor type 2 1.177e-14 0.38
AOFB_RAT Maob Amine oxidase [flavin-containing] B 1.61e-14 0.41
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 3.009e-14 0.35
SORT_HUMAN SORT1 Sortilin 7.683e-14 0.32
CTNB1_HUMAN CTNNB1 Catenin beta-1 1.082e-13 0.30
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 1.303e-13 0.32
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 2.245e-13 0.33
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 5.752e-13 0.33
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 7.588e-13 0.33
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 1.122e-12 0.34
PRIO_SHEEP PRNP Major prion protein 2.501e-12 0.31
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 8.233e-12 0.32
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 9.81e-12 0.32
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.775e-11 0.29
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 2.572e-11 0.35
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 4.228e-11 0.31
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 4.536e-11 0.32
LUCI_AQULA Luciferin 4-monooxygenase 6.768e-11 0.28
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 9.089e-11 0.33
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 9.451e-11 0.29
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.573e-10 0.31
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 1.855e-10 0.32
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 1.209e-09 0.37
HXK4_HUMAN GCK Hexokinase-4 2.297e-09 0.32
RARA_HUMAN RARA Retinoic acid receptor alpha 2.3e-09 0.43
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 4.081e-09 0.34
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 7.37e-09 0.36
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 8.719e-09 0.29
RARB_HUMAN RARB Retinoic acid receptor beta 9.015e-09 0.43
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 9.72e-09 0.32
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 1.765e-08 0.34
STXA_SHIDY stxA Shiga toxin subunit A 2.572e-08 0.29
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 3.681e-08 0.33
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 4.144e-08 0.31
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 6.095e-08 0.34
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 7.092e-08 0.30
KCNQ3_HUMAN KCNQ3 Potassium voltage-gated channel subfamily KQT member 3 7.416e-08 0.44
O68720_YERPE yopH Targeted effector protein 1.491e-07 0.29
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 1.848e-07 0.33
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 1.911e-07 0.36
TA2R8_HUMAN TAS2R8 Taste receptor type 2 member 8 2.038e-07 0.32
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 4.396e-07 0.29
KC1E_HUMAN CSNK1E Casein kinase I isoform epsilon 4.979e-07 0.30
GYRB_MYCS2 gyrB DNA gyrase subunit B 5.775e-07 0.30
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 6.879e-07 0.31
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 1.017e-06 0.41
AURKA_HUMAN AURKA Aurora kinase A 1.017e-06 0.36
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 1.298e-06 0.34
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 1.904e-06 0.34
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 3.833e-06 0.32
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 3.941e-06 0.34
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 4.608e-06 0.29
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 6.544e-06 0.31
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 6.965e-06 0.32
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 7.24e-06 0.35
KC1D_HUMAN CSNK1D Casein kinase I isoform delta 7.471e-06 0.32
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 9.756e-06 0.34
A5H660_SCHMA HDAC8 Histone deacetylase 8 9.952e-06 0.31

ZINC194556655

PANK1_HUMAN PANK1 Pantothenate kinase 1 1.167e-45 0.30
GRIP1_RAT Grip1 Glutamate receptor-interacting protein 1 3.059e-43 0.34
PANK2_HUMAN PANK2 Pantothenate kinase 2, mitochondrial 4.754e-38 0.30
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 9.698e-38 0.36
PANK3_HUMAN PANK3 Pantothenate kinase 3 1.701e-34 0.30
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 3.973e-24 0.42
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 5.927e-22 0.36
THAS_RAT Tbxas1 Thromboxane-A synthase 1.961e-21 0.39
OXDD_HUMAN DDO D-aspartate oxidase 2.917e-21 0.34
ETHR_MYCS2 ethR HTH-type transcriptional regulator EthR 4.22e-20 0.32
PAR12_HUMAN PARP12 Protein mono-ADP-ribosyltransferase PARP12 1.083e-18 0.36
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 2.372e-18 0.30
BCR_HUMAN BCR Breakpoint cluster region protein 2.446e-18 0.29
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 3.331e-16 0.33
ISPT_STRPN uppS Isoprenyl transferase 1.11e-15 0.36
KLK6_HUMAN KLK6 Kallikrein-6 2.665e-15 0.28
ADHX_HUMAN ADH5 Alcohol dehydrogenase class-3 5.995e-15 0.31
Q8IL11_PLAF7 M17 leucyl aminopeptidase 1.377e-14 0.32
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 1.632e-14 0.36
GRB7_HUMAN GRB7 Growth factor receptor-bound protein 7 9.504e-14 0.30
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 5.116e-13 0.34
ACES_ELEEL ache Acetylcholinesterase 7.059e-13 0.41
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 9.986e-13 0.36
DLDH_MYCTU lpdC Dihydrolipoyl dehydrogenase 1.099e-12 0.45
AOC2_HUMAN AOC2 Retina-specific copper amine oxidase 2.397e-12 0.30
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 3.801e-12 0.36
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 4.214e-12 0.34
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 4.414e-12 0.35
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 6.006e-12 0.36
M3K6_HUMAN MAP3K6 Mitogen-activated protein kinase kinase kinase 6 6.966e-12 0.29
PARP4_HUMAN PARP4 Protein mono-ADP-ribosyltransferase PARP4 2.683e-11 0.36
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 2.977e-11 0.31
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 4.736e-11 0.41
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 5.406e-11 0.30
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 8.336e-11 0.31
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 1.726e-10 0.35
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 4.604e-10 0.29
CP26A_HUMAN CYP26A1 Cytochrome P450 26A1 7.94e-10 0.30
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 1.628e-09 0.32
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 2.32e-09 0.37
5HT2C_MOUSE Htr2c 5-hydroxytryptamine receptor 2C 5.367e-09 0.30
GYRA_STAAU gyrA DNA gyrase subunit A 2.416e-08 0.31
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 3.043e-08 0.33
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 4.568e-08 0.32
GP142_MOUSE Gpr142 Probable G-protein coupled receptor 142 5.451e-08 0.33
OXDA_RAT Dao D-amino-acid oxidase 6.346e-08 0.34
PGH1_MOUSE Ptgs1 Prostaglandin G/H synthase 1 7.321e-08 0.31
BGLR_HUMAN GUSB Beta-glucuronidase 1.074e-07 0.31
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 1.236e-07 0.29
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 2.127e-07 0.32
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 3.629e-07 0.29
VP16_HHV11 Tegument protein VP16 5.589e-07 0.41
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.184e-06 0.33
ALBU_HUMAN ALB Serum albumin 1.21e-06 0.28
LDLR_HUMAN LDLR Low-density lipoprotein receptor 1.272e-06 0.30
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 1.633e-06 0.37
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 1.639e-06 0.32
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 2.09e-06 0.35
KLK5_HUMAN KLK5 Kallikrein-5 3.082e-06 0.28
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 4.463e-06 0.34
GASR_CANLF CCKBR Gastrin/cholecystokinin type B receptor 4.596e-06 0.29
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 5.329e-06 0.30
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 7.652e-06 0.28

ZINC565828307

MEP50_HUMAN WDR77 Methylosome protein 50 1.312e-45 0.39
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 3.786e-45 0.39
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 2.967e-41 0.41
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 1.728e-40 0.50
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 2.577e-39 0.41
CASR_BOVIN CASR Extracellular calcium-sensing receptor 2.873e-37 0.29
RASN_HUMAN NRAS GTPase NRas 8.297e-37 0.29
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.078e-30 0.38
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 2.567e-29 0.41
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 1.534e-27 0.50
CASR_HUMAN CASR Extracellular calcium-sensing receptor 2.591e-27 0.43
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 4.431e-22 0.35
ACOX1_RAT Acox1 Peroxisomal acyl-coenzyme A oxidase 1 1.484e-21 0.31
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 1.11e-16 0.31
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 1.443e-15 0.30
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 3.142e-14 0.31
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 6.637e-13 0.35
CALM_BOVIN CALM Calmodulin 1.272e-10 0.28
CASR_RAT Casr Extracellular calcium-sensing receptor 8.682e-10 0.31
TAU_HUMAN MAPT Microtubule-associated protein tau 1.851e-09 0.31
SCN1A_HUMAN SCN1A Sodium channel protein type 1 subunit alpha 9.314e-08 0.29
ESR1_RAT Esr1 Estrogen receptor 4.528e-07 0.33
SCN9A_MOUSE Scn9a Sodium channel protein type 9 subunit alpha 1.006e-06 0.29

ZINC1455894347

Q3I4V7_CRYNV CAN2 Carbonic anhydrase 3.016e-45 0.61
TYTR_CRIFA TPR Trypanothione reductase 1.071e-38 0.31
AOC2_HUMAN AOC2 Retina-specific copper amine oxidase 1.332e-34 0.30
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 6.361e-34 0.40
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 6.361e-34 0.40
PYGM_RAT Pygm Glycogen phosphorylase, muscle form 2.528e-29 0.29
CAN_CANAL NCE103 Carbonic anhydrase 3.516e-28 0.61
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 2.835e-24 0.33
GBRD_RAT Gabrd Gamma-aminobutyric acid receptor subunit delta 4.628e-24 0.30
GALE_HUMAN GALE UDP-glucose 4-epimerase 4.185e-23 0.28
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 1.079e-22 0.61
PANC_MYCTU panC Pantothenate synthetase 1.158e-20 0.39
EGFR_MOUSE Egfr Epidermal growth factor receptor 1.374e-20 0.32
PACR_HUMAN ADCYAP1R1 Pituitary adenylate cyclase-activating polypeptide type I receptor 3.089e-19 0.30
MCA_MYCTU mca Mycothiol S-conjugate amidase 6.556e-18 0.28
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 1.011e-17 0.61
GLR_HUMAN GCGR Glucagon receptor 5.551e-16 0.37
PA_I000X PA Polymerase acidic protein 3.442e-15 0.29
SYUA_HUMAN SNCA Alpha-synuclein 9.243e-13 0.32
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 2.017e-12 0.33
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 3.478e-11 0.33
CRTM_STAAU crtM 4,4'-diapophytoene synthase 2.678e-10 0.29
DOPO_RAT Dbh Dopamine beta-hydroxylase 9.255e-10 0.33
MTSI_SPISQ sssIM CPG DNA methylase 1.076e-09 0.30
GBRA6_RAT Gabra6 Gamma-aminobutyric acid receptor subunit alpha-6 1.823e-09 0.30
PFKA_TRYCC pfk ATP-dependent 6-phosphofructokinase 1.83e-09 0.30
CNR1_HUMAN CNR1 Cannabinoid receptor 1 2.507e-09 0.38
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 7.046e-09 0.38
PFKA_TRYBB pfk ATP-dependent 6-phosphofructokinase 7.529e-09 0.30
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 7.93e-09 0.35
DOPO_HUMAN DBH Dopamine beta-hydroxylase 9.732e-09 0.33
GLR_RAT Gcgr Glucagon receptor 1.314e-08 0.30
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 2.437e-08 0.31
DPOL_HHV6U U38 DNA polymerase catalytic subunit 3.505e-08 0.29
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 3.887e-08 0.31
1433G_HUMAN YWHAG 14-3-3 protein gamma 3.985e-08 0.29
SPRE_HUMAN SPR Sepiapterin reductase 7.964e-08 0.29
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 1.122e-06 0.28
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 1.331e-06 0.32
PDIA1_HUMAN P4HB Protein disulfide-isomerase 1.615e-06 0.29
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.956e-06 0.31
PTPRG_HUMAN PTPRG Receptor-type tyrosine-protein phosphatase gamma 2.849e-06 0.29
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 3.051e-06 0.32
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 6.015e-06 0.31
GBRA4_RAT Gabra4 Gamma-aminobutyric acid receptor subunit alpha-4 7.094e-06 0.30
LIPE_HUMAN LIPG Endothelial lipase 7.413e-06 0.36

ZINC24744136

AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 8.82e-45 0.34
ACHA7_MACMU CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 1.195e-36 0.29
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 5.19e-27 0.45
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 4.879e-18 0.29
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 1.11e-16 0.32
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 3.786e-14 0.32
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 7.538e-14 0.33
RNT1_ASPOR rntA Guanyl-specific ribonuclease T1 2.289e-13 0.29
PI2R_HUMAN PTGIR Prostacyclin receptor 4.469e-13 0.37
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 3.449e-11 0.34
ACRO_HUMAN ACR Acrosin 2.027e-10 0.33
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 2.963e-10 0.37
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 9.386e-09 0.29
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 2.73e-08 0.29
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 6.815e-08 0.35
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 6.815e-08 0.35
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 6.815e-08 0.35
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 6.815e-08 0.35
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 6.815e-08 0.35
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 6.815e-08 0.35
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 6.815e-08 0.35
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 6.815e-08 0.35
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 6.815e-08 0.35
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 6.815e-08 0.35
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 6.815e-08 0.35
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 6.815e-08 0.35
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 6.815e-08 0.35
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 6.815e-08 0.35
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 6.815e-08 0.35
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 6.815e-08 0.35
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 6.815e-08 0.35
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 6.815e-08 0.35
PYRD_RAT Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 5.182e-07 0.32
C3SLB7_ECOLX glmU Bifunctional protein GlmU 8.896e-07 0.32
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 1.2e-06 0.31
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.369e-06 0.29
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 4.733e-06 0.42
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 6.043e-06 0.46
AURKA_HUMAN AURKA Aurora kinase A 6.981e-06 0.42
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 8.711e-06 0.33

ZINC1207542374

ANM3_HUMAN PRMT3 Protein arginine N-methyltransferase 3 1.34e-44 0.43
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 2.416e-38 0.35
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 2.643e-24 0.31
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 3.464e-23 0.39
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 1.435e-20 0.60
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.833e-20 0.46
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 7.53e-19 0.39
Q9HUN3_PSEAE dnaB Replicative DNA helicase 3.084e-13 0.29
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 1.756e-12 0.31
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 1.471e-09 0.45
Q6FTL6_CANGA NCE103 Carbonic anhydrase 5.301e-08 0.36
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 5.69e-08 0.33
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 5.909e-08 0.35
PTN7_HUMAN PTPN7 Tyrosine-protein phosphatase non-receptor type 7 1.651e-07 0.37
5HT1D_RAT Htr1d 5-hydroxytryptamine receptor 1D 1.898e-07 0.31
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 2.434e-07 0.41
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 5.972e-07 0.30
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 7.01e-07 0.33
GYRB_MYCS2 gyrB DNA gyrase subunit B 9.396e-07 0.29
LDHA_HUMAN LDHA L-lactate dehydrogenase A chain 1.245e-06 0.33
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.869e-06 0.31
PRIO_SHEEP PRNP Major prion protein 2.558e-06 0.29
EGLN2_HUMAN EGLN2 Egl nine homolog 2 4.415e-06 0.31
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 6.908e-06 0.34
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 6.914e-06 0.29
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 6.914e-06 0.29
CAN_CANAL NCE103 Carbonic anhydrase 8.198e-06 0.36
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 9.291e-06 0.34

ZINC663997290

UBP10_HUMAN USP10 Ubiquitin carboxyl-terminal hydrolase 10 5.166e-42 0.33
UBP13_HUMAN USP13 Ubiquitin carboxyl-terminal hydrolase 13 5.166e-42 0.33
HD_HUMAN HTT Huntingtin 4.798e-31 0.37
CD38_MOUSE Cd38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 1.541e-21 0.35
CCRL2_HUMAN CCRL2 C-C chemokine receptor-like 2 5.844e-21 0.33
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 9.412e-18 0.46
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 1.11e-16 0.48
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 3.442e-15 0.48
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 8.567e-12 0.39
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 2.388e-11 0.43
EGFR_HUMAN EGFR Epidermal growth factor receptor 3.641e-11 0.39
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.4e-10 0.39
CDN1A_HUMAN CDKN1A Cyclin-dependent kinase inhibitor 1 4.813e-10 0.34
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 1.359e-09 0.34
LUCI_RENRE Coelenterazine h 2-monooxygenase 1.229e-08 0.31
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.773e-08 0.48
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 2.511e-08 0.48
EGFR_MOUSE Egfr Epidermal growth factor receptor 5.904e-07 0.28
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 1.054e-06 0.28
PGK1_HUMAN PGK1 Phosphoglycerate kinase 1 1.27e-06 0.32

ZINC1121360286

LOX5_MOUSE Alox5 Arachidonate 5-lipoxygenase 4.007e-40 0.33
C560_PIG SDHC Succinate dehydrogenase cytochrome b560 subunit, mitochondrial 1.605e-23 0.29
DHSD_PIG SDHD Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial 1.605e-23 0.29
NPY5R_MOUSE Npy5r Neuropeptide Y receptor type 5 4.034e-21 0.31
TNF11_MOUSE Tnfsf11 Tumor necrosis factor ligand superfamily member 11 7.645e-21 0.29
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 4.75e-12 0.31
GLUC_HUMAN GCG Glucagon 4.606e-11 0.32
IL6_HUMAN IL6 Interleukin-6 4.299e-09 0.36
MKNK2_HUMAN MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 5.911e-07 0.30

ZINC760541736

MSRE_MOUSE Msr1 Macrophage scavenger receptor types I and II 1.157e-39 0.31
CXCR2_RABIT CXCR2 C-X-C chemokine receptor type 2 1.339e-33 0.29
TERT_HUMAN TERT Telomerase reverse transcriptase 3.111e-30 0.42
GYRA_STAAU gyrA DNA gyrase subunit A 1.123e-19 0.34
LDLR_HUMAN LDLR Low-density lipoprotein receptor 3.831e-18 0.30
PAR12_HUMAN PARP12 Protein mono-ADP-ribosyltransferase PARP12 6.307e-18 0.34
5HT1D_PIG HTR1D 5-hydroxytryptamine receptor 1D 2.22e-16 0.35
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 6.328e-14 0.34
HDAC2_HUMAN HDAC2 Histone deacetylase 2 1.529e-13 0.37
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.598e-12 0.37
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.964e-12 0.30
HDAC1_HUMAN HDAC1 Histone deacetylase 1 2.923e-12 0.37
GYRB_STAAU gyrB DNA gyrase subunit B 3.006e-12 0.34
CNR2_RAT Cnr2 Cannabinoid receptor 2 8.437e-12 0.39
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 1.165e-11 0.34
PARP4_HUMAN PARP4 Protein mono-ADP-ribosyltransferase PARP4 7.571e-11 0.34
UT1_RAT Slc14a1 Urea transporter 1 1.105e-10 0.29
ACES_ELEEL ache Acetylcholinesterase 5.099e-08 0.38
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 6.73e-08 0.34
HDAC8_HUMAN HDAC8 Histone deacetylase 8 6.892e-08 0.37
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 7.65e-08 0.31
HDAC6_HUMAN HDAC6 Histone deacetylase 6 2.863e-07 0.37
AKT1_MOUSE Akt1 RAC-alpha serine/threonine-protein kinase 6.033e-07 0.29
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 1.176e-06 0.31
HDAC9_HUMAN HDAC9 Histone deacetylase 9 2.344e-06 0.37
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 5.154e-06 0.34
CNR2_HUMAN CNR2 Cannabinoid receptor 2 6.427e-06 0.40

ZINC831434972

TYTR_CRIFA TPR Trypanothione reductase 7.528e-39 0.31
ACES_BOVIN ACHE Acetylcholinesterase 2.235e-31 0.36
CHLE_HUMAN BCHE Cholinesterase 8.549e-15 0.36
M3K11_MOUSE Map3k11 Mitogen-activated protein kinase kinase kinase 11 2.757e-12 0.30
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 1.64e-11 0.36
ACES_TETCF ache Acetylcholinesterase 2.051e-10 0.34
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 4.726e-10 0.33
ACES_HUMAN ACHE Acetylcholinesterase 1.509e-09 0.36
DLK1_HUMAN DLK1 Protein delta homolog 1 5.367e-09 0.30

ZINC738360286

HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 1.233e-34 0.36
BKRB2_RAT Bdkrb2 B2 bradykinin receptor 5.02e-27 0.32
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 6.917e-20 0.30
TAT_HV1H2 tat Protein Tat 3.034e-19 0.29
DYR_RAT Dhfr Dihydrofolate reductase 4.907e-14 0.43
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 6.284e-14 0.38
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 2.226e-13 0.32
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 1.376e-10 0.29
GASR_BOVIN CCKBR Gastrin/cholecystokinin type B receptor 1.718e-08 0.28
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 3.394e-08 0.31
DYR_PNECA Dihydrofolate reductase 5.019e-08 0.43
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 1.131e-07 0.32
CBPA1_HUMAN CPA1 Carboxypeptidase A1 1.979e-07 0.30
BLA1_STEMA Metallo-beta-lactamase L1 type 3 3.292e-07 0.33
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 7.045e-07 0.29
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 7.185e-07 0.30
B2CL1_HUMAN BCL2L1 Bcl-2-like protein 1 7.56e-07 0.34
DRTS_TOXGO Bifunctional dihydrofolate reductase-thymidylate synthase 1.041e-06 0.43
KAT2B_HUMAN KAT2B Histone acetyltransferase KAT2B 1.339e-06 0.30
TOP3_BACSU topB DNA topoisomerase 3 2.488e-06 0.30
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 5.379e-06 0.29
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 7.192e-06 0.29

ZINC791218181

TRPM8_MOUSE Trpm8 Transient receptor potential cation channel subfamily M member 8 2.851e-34 0.31
GBRA1_RAT Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 4.234e-26 0.33
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 1.286e-25 0.33
GBRG2_RAT Gabrg2 Gamma-aminobutyric acid receptor subunit gamma-2 1.068e-23 0.33
MDHM_PIG MDH2 Malate dehydrogenase, mitochondrial 1.123e-21 0.34
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 6.715e-21 0.31
Q7K6A1_PLAF7 Histone deacetylase 3.68e-20 0.32
GBRA5_RAT Gabra5 Gamma-aminobutyric acid receptor subunit alpha-5 9.085e-19 0.29
GBRB3_RAT Gabrb3 Gamma-aminobutyric acid receptor subunit beta-3 1.679e-18 0.29
MECP2_HUMAN MECP2 Methyl-CpG-binding protein 2 6.556e-18 0.28
LMP1_EBVB9 LMP1 Latent membrane protein 1 1.11e-16 0.41
EGLN1_HUMAN EGLN1 Egl nine homolog 1 3.331e-16 0.42
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.634e-13 0.33
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 2.413e-13 0.34
HISX_BRUSU hisD Histidinol dehydrogenase 4.735e-13 0.30
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 6.404e-13 0.32
CFTR_HUMAN CFTR Cystic fibrosis transmembrane conductance regulator 7.968e-13 0.38
BXA1_CLOBO botA Botulinum neurotoxin type A 1.03e-12 0.36
MEP50_HUMAN WDR77 Methylosome protein 50 1.978e-12 0.32
Q5NGQ3_FRATT fabI Enoyl-[acyl-carrier-protein] reductase [NADH] 2.757e-12 0.30
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 3.013e-12 0.34
DKK1_HUMAN DKK1 Dickkopf-related protein 1 6.966e-12 0.29
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 2.498e-11 0.33
ACOD1_MOUSE Scd1 Acyl-CoA desaturase 1 3.947e-10 0.30
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 5.743e-10 0.32
ATS5_HUMAN ADAMTS5 A disintegrin and metalloproteinase with thrombospondin motifs 5 1.318e-09 0.32
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 2.415e-09 0.31
UR2R_HUMAN UTS2R Urotensin-2 receptor 3.245e-08 0.33
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 5.058e-08 0.28
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 6.556e-08 0.37
Q7ZJM1_9HIV1 pol Integrase 1.638e-07 0.38
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 1.879e-07 0.29
Q8IL32_PLAF7 Heat shock protein 90, putative 2.57e-07 0.41
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 3.14e-07 0.31
DRD2_MOUSE Drd2 D(2) dopamine receptor 3.426e-07 0.31
Q76353_9HIV1 Integrase 3.888e-07 0.38
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 3.914e-07 0.33
CALCA_HUMAN CALCA Calcitonin gene-related peptide 1 5.587e-07 0.29
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 5.908e-07 0.36
ACOD_HUMAN SCD Acyl-CoA desaturase 9.49e-07 0.30
KDM4B_HUMAN KDM4B Lysine-specific demethylase 4B 3.751e-06 0.32
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 4.696e-06 0.31
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 4.884e-06 0.31
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 6.155e-06 0.32
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 7.112e-06 0.29
FACE2_HUMAN RCE1 CAAX prenyl protease 2 7.771e-06 0.31
CAN1_RAT Capn1 Calpain-1 catalytic subunit 8.279e-06 0.28
STABP_HUMAN STAMBP STAM-binding protein 8.364e-06 0.29
AA1R_BOVIN ADORA1 Adenosine receptor A1 8.368e-06 0.38

ZINC552125808

GRM5_MOUSE Grm5 Metabotropic glutamate receptor 5 2.913e-33 0.33
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 8.712e-23 0.35
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 1.818e-19 0.29
AA3R_HUMAN ADORA3 Adenosine receptor A3 4.552e-15 0.37
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 2.376e-14 0.34
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 6.928e-14 0.30
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 3.437e-13 0.31
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 1.136e-11 0.31
TAAR1_RAT Taar1 Trace amine-associated receptor 1 2.487e-11 0.44
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 1.17e-08 0.30
AA1R_BOVIN ADORA1 Adenosine receptor A1 3.045e-08 0.34
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 1.509e-07 0.44
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 1.721e-07 0.29
CLK2_MOUSE Clk2 Dual specificity protein kinase CLK2 2.012e-07 0.33
CLK4_MOUSE Clk4 Dual specificity protein kinase CLK4 2.012e-07 0.33
KLF5_HUMAN KLF5 Krueppel-like factor 5 2.342e-07 0.33
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 4.963e-07 0.34
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 8.266e-07 0.31
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 1.394e-06 0.32
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 3.01e-06 0.31
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 3.592e-06 0.29
LUCI_AQULA Luciferin 4-monooxygenase 4.23e-06 0.30
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 6.407e-06 0.32
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 7.842e-06 0.30
RXFP1_HUMAN RXFP1 Relaxin receptor 1 7.966e-06 0.29
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 8.404e-06 0.28

ZINC1450070720

SMO_HUMAN SMO Smoothened homolog 1.044e-29 0.34
CLTR1_CAVPO CYSLTR1 Cysteinyl leukotriene receptor 1 4.218e-26 0.36
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 1.739e-13 0.28
HSP12_CAEEL hsp-16.2 Heat shock protein Hsp-16.2 4.661e-10 0.29
TRPM8_MOUSE Trpm8 Transient receptor potential cation channel subfamily M member 8 9.735e-10 0.32
O31272_9GAMM imiS Beta-lactamase 4.608e-09 0.28
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 6.823e-09 0.31
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 1.694e-07 0.32
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 5.371e-07 0.29
AL5AP_HUMAN ALOX5AP Arachidonate 5-lipoxygenase-activating protein 8.997e-07 0.35
LUCI_AQULA Luciferin 4-monooxygenase 1.578e-06 0.32
CTNB1_HUMAN CTNNB1 Catenin beta-1 1.871e-06 0.29
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 2e-06 0.30
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 2.478e-06 0.32
CLTR1_HUMAN CYSLTR1 Cysteinyl leukotriene receptor 1 2.719e-06 0.32
STABP_HUMAN STAMBP STAM-binding protein 8.364e-06 0.29

ZINC1607650999

TERA_HUMAN VCP Transitional endoplasmic reticulum ATPase 1.542e-27 0.35
SORT_HUMAN SORT1 Sortilin 2.806e-25 0.47
A6QR73_RAT Gpr39 G protein-coupled receptor 39 1.494e-23 0.31
PSIP1_HUMAN PSIP1 PC4 and SFRS1-interacting protein 1.944e-23 0.30
GPR39_MOUSE Gpr39 G-protein coupled receptor 39 2.324e-23 0.31
MAP2_HUMAN METAP2 Methionine aminopeptidase 2 3.331e-16 0.34
MTR1B_CHICK Melatonin receptor type 1B 2.047e-13 0.29
TP53B_HUMAN TP53BP1 TP53-binding protein 1 3.922e-13 0.29
GPR39_HUMAN GPR39 G-protein coupled receptor 39 7.421e-13 0.31
V2R_HUMAN AVPR2 Vasopressin V2 receptor 7.511e-13 0.32
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 4.116e-12 0.29
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 4.097e-10 0.29
Q38C41_TRYB2 Phosphotransferase 9.207e-10 0.34
MTSI_SPISQ sssIM CPG DNA methylase 2.533e-09 0.29
MOT4_HUMAN SLC16A3 Monocarboxylate transporter 4 3.598e-09 0.29
ACES_BOVIN ACHE Acetylcholinesterase 6.843e-09 0.29
B2CL2_HUMAN BCL2L2 Bcl-2-like protein 2 2e-08 0.30
RXRG_MOUSE Rxrg Retinoic acid receptor RXR-gamma 2.028e-08 0.32
RXRB_MOUSE Rxrb Retinoic acid receptor RXR-beta 2.98e-08 0.32
HRH4_HUMAN HRH4 Histamine H4 receptor 3.169e-08 0.35
CHLE_HORSE BCHE Cholinesterase 1.47e-07 0.29
CXCR5_HUMAN CXCR5 C-X-C chemokine receptor type 5 9.356e-07 0.29
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 1.032e-06 0.29
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 1.21e-06 0.28
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 2.333e-06 0.30
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 3.477e-06 0.28
ACES_HUMAN ACHE Acetylcholinesterase 5.547e-06 0.35
ACES_ELEEL ache Acetylcholinesterase 9.594e-06 0.31

ZINC750333272

MPC2_HUMAN MPC2 Mitochondrial pyruvate carrier 2 2.063e-23 0.29
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.731e-09 0.34
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 6.763e-09 0.30
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 1.176e-06 0.30
B2RXC2_MOUSE Itpkb Kinase 1.697e-06 0.30
THAS_RAT Tbxas1 Thromboxane-A synthase 3.893e-06 0.34

ZINC555600304

SUCR1_RAT Sucnr1 Succinate receptor 1 3.796e-23 0.30
SOAT1_MOUSE Soat1 Sterol O-acyltransferase 1 4.356e-20 0.30
SUCR1_HUMAN SUCNR1 Succinate receptor 1 9.728e-19 0.32
Q9FBC5_STREE fabK Enoyl-ACP reductase II 2.727e-18 0.30
OXGR1_HUMAN OXGR1 2-oxoglutarate receptor 1 6.229e-18 0.28
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.471e-12 0.29
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 9.926e-12 0.28
TNF11_MOUSE Tnfsf11 Tumor necrosis factor ligand superfamily member 11 5.087e-11 0.30
POLG_CXB3N Genome polyprotein 7.504e-11 0.30
SENP8_HUMAN SENP8 Sentrin-specific protease 8 1.366e-10 0.36
SENP6_HUMAN SENP6 Sentrin-specific protease 6 5.483e-09 0.36
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 3.445e-07 0.31
SENP7_HUMAN SENP7 Sentrin-specific protease 7 1.934e-06 0.36
GYRA_STAAU gyrA DNA gyrase subunit A 4.186e-06 0.32

ZINC355846271

M3K11_MOUSE Map3k11 Mitogen-activated protein kinase kinase kinase 11 1.967e-22 0.28
CLK2_MOUSE Clk2 Dual specificity protein kinase CLK2 5.807e-11 0.38
CLK4_MOUSE Clk4 Dual specificity protein kinase CLK4 5.807e-11 0.38
CLK3_MOUSE Clk3 Dual specificity protein kinase CLK3 4.019e-10 0.38
DYRK2_HUMAN DYRK2 Dual specificity tyrosine-phosphorylation-regulated kinase 2 1.804e-09 0.38
CLK1_MOUSE Clk1 Dual specificity protein kinase CLK1 1.618e-07 0.38

ZINC346954448

RAD1_HUMAN RAD1 Cell cycle checkpoint protein RAD1 9.314e-20 0.31
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 6.661e-16 0.46
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 1.669e-09 0.46
TGFR1_MOUSE Tgfbr1 TGF-beta receptor type-1 2.869e-07 0.28
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 2.175e-06 0.31
THAS_RAT Tbxas1 Thromboxane-A synthase 6.553e-06 0.31

ZINC579888995

Q72547_9HIV1 pol Reverse transcriptase/RNaseH 6.221e-12 0.46
DRD4_RAT Drd4 D(4) dopamine receptor 1.17e-06 0.33

ZINC572926896

SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 1.055e-06 0.30