Results of Job: search_d22a434f-e460-44d7-8210-a001e7c87487

Query Target Key Target Name Description P-Value MaxTC

compound_1

AURKA_HUMAN AURKA Aurora kinase A 5.876e-122 0.59
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 1.045e-117 0.59
EGFR_HUMAN EGFR Epidermal growth factor receptor 2.558e-102 0.48
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 4.831e-96 0.56
CTNB1_HUMAN CTNNB1 Catenin beta-1 1.437e-88 0.56
AURKB_HUMAN AURKB Aurora kinase B 2.248e-72 0.50
C3SLB7_ECOLX glmU Bifunctional protein GlmU 3.565e-67 0.48
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 1.621e-66 0.43
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 5.909e-64 0.38
SHH_MOUSE Shh Sonic hedgehog protein 1.254e-59 0.42
PRIO_SHEEP PRNP Major prion protein 7.911e-55 0.41
TPOR_HUMAN MPL Thrombopoietin receptor 3.046e-54 0.36
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 1.708e-52 0.48
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 1.004e-48 0.32
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 5.227e-48 0.34
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 2.895e-44 0.41
DUS2L_HUMAN DUS2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like 3.092e-44 0.35
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 4.854e-43 0.35
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 4.195e-42 0.47
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.06e-41 0.38
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 3.015e-38 0.35
AURKB_MOUSE Aurkb Aurora kinase B 2.873e-37 0.29
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 2.261e-34 0.37
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 2.417e-34 0.34
LCK_HUMAN LCK Tyrosine-protein kinase Lck 2.686e-32 0.38
PSBA_SPIOL psbA Photosystem II protein D1 1.05e-31 0.33
TAAR1_RAT Taar1 Trace amine-associated receptor 1 2.985e-31 0.39
HSPB1_HUMAN HSPB1 Heat shock protein beta-1 2.93e-30 0.29
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 1.193e-29 0.43
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 9.128e-29 0.53
ENL_HUMAN MLLT1 Protein ENL 2.859e-26 0.32
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 3.633e-26 0.32
AURKA_MOUSE Aurka Aurora kinase A 1.077e-25 0.29
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 6.062e-25 0.39
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 2.937e-24 0.38
AUKBA_XENLA aurkb-a Aurora kinase B-A 1.072e-23 0.38
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.095e-23 0.53
GBRD_RAT Gabrd Gamma-aminobutyric acid receptor subunit delta 2.847e-23 0.29
LUCI_AQULA Luciferin 4-monooxygenase 3.371e-23 0.34
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 4.565e-23 0.34
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 4.705e-23 0.37
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 1.803e-22 0.36
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 3.207e-22 0.44
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 6.296e-22 0.32
GRM1_HUMAN GRM1 Metabotropic glutamate receptor 1 4.249e-21 0.38
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 5.417e-21 0.40
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 5.703e-21 0.35
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 6.911e-21 0.34
APOB_HUMAN APOB Apolipoprotein B-100 1.079e-20 0.31
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 1.379e-20 0.34
EGFR_MOUSE Egfr Epidermal growth factor receptor 2.867e-20 0.31
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 3.492e-20 0.32
EPHB_MYCTO Epoxide hydrolase B 8.656e-20 0.31
CD38_MOUSE Cd38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 1.057e-19 0.37
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 3.131e-19 0.36
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 5.444e-19 0.32
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 5.447e-19 0.37
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 1.002e-18 0.38
FA10_HUMAN F10 Coagulation factor X 1.491e-18 0.41
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 3.538e-18 0.35
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 4.315e-18 0.32
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 5.37e-18 0.37
V1AR_RAT Avpr1a Vasopressin V1a receptor 7.967e-18 0.36
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 1.216e-17 0.32
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 1.509e-17 0.43
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 1.942e-17 0.40
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 2.847e-17 0.36
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 3.569e-17 0.32
LIMK1_RAT Limk1 LIM domain kinase 1 4.697e-17 0.31
CCNA1_HUMAN CCNA1 Cyclin-A1 1.11e-16 0.33
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 1.11e-16 0.32
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 2.22e-16 0.43
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 3.331e-16 0.31
TIE2_HUMAN TEK Angiopoietin-1 receptor 3.331e-16 0.34
V2R_RAT Avpr2 Vasopressin V2 receptor 3.331e-16 0.36
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 7.772e-16 0.40
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 9.992e-16 0.45
SENP7_HUMAN SENP7 Sentrin-specific protease 7 1.332e-15 0.37
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 1.998e-15 0.37
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 2.109e-15 0.37
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 2.665e-15 0.38
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 4.441e-15 0.38
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 8.216e-15 0.38
KCNQ2_RAT Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 9.104e-15 0.36
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 1.033e-14 0.41
TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 1.199e-14 0.34
Q25615_ONCVO Chitinase 1.998e-14 0.34
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 2.22e-14 0.34
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 2.298e-14 0.31
TNR16_HUMAN NGFR Tumor necrosis factor receptor superfamily member 16 2.298e-14 0.31
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 5.262e-14 0.44
HDAC1_HUMAN HDAC1 Histone deacetylase 1 5.329e-14 0.42
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 7.772e-14 0.44
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 1.195e-13 0.37
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 1.205e-13 0.35
Q38C41_TRYB2 Phosphotransferase 1.206e-13 0.29
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 1.428e-13 0.37
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.68e-13 0.37
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 2.263e-13 0.37
BTK_HUMAN BTK Tyrosine-protein kinase BTK 2.539e-13 0.38
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 3.532e-13 0.43
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 5.25e-13 0.32
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 6.746e-13 0.34
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 7.834e-13 0.31
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 9.187e-13 0.43
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 2.25e-12 0.40
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 2.455e-12 0.36
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 2.538e-12 0.38
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 2.983e-12 0.37
HDAC3_HUMAN HDAC3 Histone deacetylase 3 5.678e-12 0.42
ANDR_MOUSE Ar Androgen receptor 7.057e-12 0.29
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 7.41e-12 0.34
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 7.643e-12 0.31
CCNK_HUMAN CCNK Cyclin-K 9.554e-12 0.32
KCJ11_HUMAN KCNJ11 ATP-sensitive inward rectifier potassium channel 11 1.093e-11 0.33
O61059_LEIME LmGT2 Glucose transporter 2.694e-11 0.36
ECR_BOMMO EcR Ecdysone receptor 3.919e-11 0.31
E3UJZ5_SPOLI Ecdysone receptor 3.972e-11 0.30
AOFB_RAT Maob Amine oxidase [flavin-containing] B 5.332e-11 0.32
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 6.145e-11 0.31
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 6.485e-11 0.40
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 9.395e-11 0.38
A5H660_SCHMA HDAC8 Histone deacetylase 8 9.483e-11 0.31
GRM5_HUMAN GRM5 Metabotropic glutamate receptor 5 1.236e-10 0.35
O97467_PLAFA ht1 Hexose transporter 1 1.339e-10 0.36
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 1.67e-10 0.34
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 2.114e-10 0.36
PSBA_MARPO psbA Photosystem II protein D1 2.222e-10 0.33
M3K5_HUMAN MAP3K5 Mitogen-activated protein kinase kinase kinase 5 3.934e-10 0.32
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 4.013e-10 0.40
LCK_MOUSE Lck Proto-oncogene tyrosine-protein kinase LCK 4.438e-10 0.31
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 4.633e-10 0.45
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 5.115e-10 0.45
UREA_CANEN Urease 6.803e-10 0.32
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 6.93e-10 0.36
CNR1_HUMAN CNR1 Cannabinoid receptor 1 7.371e-10 0.37
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 7.587e-10 0.35
HDAC6_HUMAN HDAC6 Histone deacetylase 6 9.023e-10 0.37
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 9.542e-10 0.38
ACRO_HUMAN ACR Acrosin 9.59e-10 0.30
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 1.224e-09 0.31
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 1.357e-09 0.36
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 2.144e-09 0.31
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 2.18e-09 0.31
ENPP3_HUMAN ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 2.184e-09 0.29
SIK1_HUMAN SIK1 Serine/threonine-protein kinase SIK1 3.073e-09 0.36
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 3.283e-09 0.36
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 3.305e-09 0.31
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 3.305e-09 0.31
GBRA6_RAT Gabra6 Gamma-aminobutyric acid receptor subunit alpha-6 3.598e-09 0.29
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 4.19e-09 0.37
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 5.195e-09 0.31
HPSE_HUMAN HPSE Heparanase 5.271e-09 0.35
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 6.152e-09 0.44
STRP_STRP1 ska Streptokinase A 7.403e-09 0.37
SENP6_HUMAN SENP6 Sentrin-specific protease 6 1.034e-08 0.40
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 2.082e-08 0.31
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 2.16e-08 0.40
TXK_HUMAN TXK Tyrosine-protein kinase TXK 2.467e-08 0.31
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 2.624e-08 0.32
HCK_HUMAN HCK Tyrosine-protein kinase HCK 3.07e-08 0.36
CTRO_HUMAN CIT Citron Rho-interacting kinase 3.379e-08 0.31
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 5.175e-08 0.31
AA3R_HUMAN ADORA3 Adenosine receptor A3 5.294e-08 0.39
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 5.611e-08 0.30
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 8.611e-08 0.41
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 9.238e-08 0.31
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 1.017e-07 0.33
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 1.095e-07 0.34
IL6_HUMAN IL6 Interleukin-6 1.106e-07 0.30
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 1.155e-07 0.31
TEC_HUMAN TEC Tyrosine-protein kinase Tec 1.185e-07 0.29
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 1.328e-07 0.33
SCNAA_HUMAN SCN10A Sodium channel protein type 10 subunit alpha 1.406e-07 0.38
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 1.411e-07 0.33
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 1.657e-07 0.32
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 2.121e-07 0.31
BCAT2_HUMAN BCAT2 Branched-chain-amino-acid aminotransferase, mitochondrial 2.141e-07 0.34
GATA4_MOUSE Gata4 Transcription factor GATA-4 2.196e-07 0.30
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 2.196e-07 0.30
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 2.574e-07 0.31
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 3.001e-07 0.37
LIMK1_HUMAN LIMK1 LIM domain kinase 1 3.96e-07 0.36
SMO_HUMAN SMO Smoothened homolog 4.792e-07 0.35
CAH7_HUMAN CA7 Carbonic anhydrase 7 4.851e-07 0.36
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 5.284e-07 0.34
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 5.49e-07 0.33
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 5.533e-07 0.28
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 5.759e-07 0.36
CYNT_HELPY cynT Carbonic anhydrase 6.917e-07 0.31
GYRB_MYCS2 gyrB DNA gyrase subunit B 7.69e-07 0.29
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 7.97e-07 0.31
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 8.09e-07 0.32
CAH4_HUMAN CA4 Carbonic anhydrase 4 8.195e-07 0.36
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 8.66e-07 0.38
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 9.152e-07 0.31
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 9.667e-07 0.34
UROK_HUMAN PLAU Urokinase-type plasminogen activator 1.184e-06 0.38
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 1.347e-06 0.31
KCNQ3_HUMAN KCNQ3 Potassium voltage-gated channel subfamily KQT member 3 1.535e-06 0.36
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 1.662e-06 0.37
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 1.851e-06 0.31
AURKC_HUMAN AURKC Aurora kinase C 1.941e-06 0.31
SCAF_HCMVA UL80 Capsid scaffolding protein 2.206e-06 0.32
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 2.212e-06 0.31
FFAR2_HUMAN FFAR2 Free fatty acid receptor 2 2.326e-06 0.29
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 2.391e-06 0.36
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 2.412e-06 0.37
TPA_HUMAN PLAT Tissue-type plasminogen activator 2.515e-06 0.38
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 2.545e-06 0.37
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 2.622e-06 0.37
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 2.628e-06 0.31
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 2.845e-06 0.30
YES_HUMAN YES1 Tyrosine-protein kinase Yes 2.88e-06 0.31
EST1_HUMAN CES1 Liver carboxylesterase 1 2.885e-06 0.33
Q76129_9HIV1 gag Structural capsid protein 3.283e-06 0.30
NR1H4_HUMAN NR1H4 Bile acid receptor 3.777e-06 0.34
NCOA1_HUMAN NCOA1 Nuclear receptor coactivator 1 3.786e-06 0.31
V2R_HUMAN AVPR2 Vasopressin V2 receptor 3.997e-06 0.30
FRK_HUMAN FRK Tyrosine-protein kinase FRK 4.46e-06 0.37
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 6.091e-06 0.33
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 6.414e-06 0.31
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 6.674e-06 0.34
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 7.637e-06 0.37
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 8.2e-06 0.29
GABT_RAT Abat 4-aminobutyrate aminotransferase, mitochondrial 8.294e-06 0.30
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 8.351e-06 0.36
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 8.752e-06 0.31
Q8MWR1_SPOFR USP Ultraspiracle protein 8.827e-06 0.29
Q8MWR2_SPOFR EcR Ecdysteroid receptor 8.827e-06 0.29
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 9.573e-06 0.31
G2YM83_BOTF4 Cytochrome b-c1 complex subunit Rieske, mitochondrial 9.736e-06 0.29