Results of Job: search_dafecaf1-50fd-4006-a54e-1e8486d6d2d3

Query Target Key Target Name Description P-Value MaxTC

Fludarabine

AA1R_RAT Adora1 Adenosine receptor A1 2.571e-281 1.00
AA2AR_RAT Adora2a Adenosine receptor A2a 3.698e-190 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 8.575e-163 1.00
HSF1_MOUSE Hsf1 Heat shock factor protein 1 0.001637 1.00
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 6.654e-195 0.58
OXGR1_RAT Oxgr1 2-oxoglutarate receptor 1 4.166e-183 0.45
ADK_TOXGO AK Adenosine kinase 6.362e-173 0.68
MBTA_MYCTU mbtA Salicyl-AMP ligase / salicyl-S-ArCP synthetase 2.228e-172 0.44
AA3R_RAT Adora3 Adenosine receptor A3 1.915e-171 0.74
ADOK_MYCTO adoK Adenosine kinase 1.881e-162 0.41
SAHH_HUMAN AHCY Adenosylhomocysteinase 5.732e-156 0.57
AA1R_CHICK ADORA1 Adenosine receptor A1 2.279e-148 0.54
C3SIU2_ECOLX metJ Met repressor 7.216e-137 0.43
AA1R_RABIT ADORA1 Adenosine receptor A1 5.832e-136 0.44
S28A2_HUMAN SLC28A2 Sodium/nucleoside cotransporter 2 1.119e-134 0.41
AA3R_RABIT ADORA3 Adenosine receptor A3 1.152e-133 0.44
DCAM_HUMAN AMD1 S-adenosylmethionine decarboxylase proenzyme 8.567e-130 0.51
AA1R_HUMAN ADORA1 Adenosine receptor A1 3.097e-128 0.74
DOT1L_HUMAN DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.435e-123 0.44
AA1R_CAVPO ADORA1 Adenosine receptor A1 3.094e-123 0.74
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 1.852e-117 0.63
DNPH1_HUMAN DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 9.384e-117 0.35
DNPH1_RAT Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 5.094e-115 0.35
MTAP_MOUSE Mtap S-methyl-5'-thioadenosine phosphorylase 2.516e-113 0.52
SAHH_RAT Ahcy Adenosylhomocysteinase 3.563e-112 0.47
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 1.354e-104 0.74
BIP_HUMAN HSPA5 Endoplasmic reticulum chaperone BiP 5.06e-104 0.50
P2RY1_RAT P2ry1 P2Y purinoceptor 1 1.974e-102 0.49
CDD_MOUSE Cda Cytidine deaminase 4.317e-102 0.50
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 2.13e-97 0.49
IMDH1_HUMAN IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 2.355e-96 0.44
G3PC_LEIME GAPC Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 9.689e-91 0.35
SAHH_MOUSE Ahcy Adenosylhomocysteinase 1.56e-90 0.47
SAHH_PLAF7 Adenosylhomocysteinase 1.045e-89 0.60
ADK_HUMAN ADK Adenosine kinase 4.491e-88 0.68
SPEE_HUMAN SRM Spermidine synthase 3.642e-84 0.43
CDD_HUMAN CDA Cytidine deaminase 2.86e-81 0.42
Q99MI5_RAT LOC100912604 Spermidine synthase 2.849e-76 0.43
SYQ_HUMAN QARS1 Glutamine--tRNA ligase 1.92e-73 0.45
KAD2_RAT Ak2 Adenylate kinase 2, mitochondrial 1.025e-71 0.46
ASNS_HUMAN ASNS Asparagine synthetase [glutamine-hydrolyzing] 1.296e-71 0.40
G3P_HUMAN GAPDH Glyceraldehyde-3-phosphate dehydrogenase 2.512e-71 0.74
P2Y11_HUMAN P2RY11 P2Y purinoceptor 11 2.855e-71 0.44
IMDH2_MOUSE Impdh2 Inosine-5'-monophosphate dehydrogenase 2 1.113e-70 0.40
RASK_HUMAN KRAS GTPase KRas 5.524e-69 0.37
HSP7C_HUMAN HSPA8 Heat shock cognate 71 kDa protein 9.404e-69 0.50
KAD3_RAT Ak3 GTP:AMP phosphotransferase AK3, mitochondrial 8.622e-67 0.46
P96884_MYCTO birA BirA bifunctional protein 1.823e-66 0.36
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 3.864e-66 0.43
NADK_HUMAN NADK NAD kinase 4.632e-66 0.46
FUT6_HUMAN FUT6 Alpha-(1,3)-fucosyltransferase 6 8.838e-66 0.31
SPSY_HUMAN SMS Spermine synthase 3.14e-65 0.42
PQSA_PSEAE pqsA Anthranilate--CoA ligase 6.042e-65 0.41
IF4E_RABIT EIF4E Eukaryotic translation initiation factor 4E 3.478e-64 0.41
ADA_MOUSE Ada Adenosine deaminase 8.556e-64 0.42
NADK1_LISMF nadK1 NAD kinase 1 1.697e-63 0.51
NADK_STAAC nadK NAD kinase 1.697e-63 0.51
SAHH2_HUMAN AHCYL1 S-adenosylhomocysteine hydrolase-like protein 1 2.952e-61 0.33
DHE3_BOVIN GLUD1 Glutamate dehydrogenase 1, mitochondrial 4.937e-60 0.40
SYRC_HUMAN RARS1 Arginine--tRNA ligase, cytoplasmic 6.114e-60 0.38
MACD1_HUMAN MACROD1 ADP-ribose glycohydrolase MACROD1 1.225e-59 0.48
MACD2_HUMAN MACROD2 ADP-ribose glycohydrolase MACROD2 1.225e-59 0.48
KTHY_HUMAN DTYMK Thymidylate kinase 5.233e-57 0.34
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 6.313e-57 0.48
P2RX5_RAT P2rx5 P2X purinoceptor 5 2.408e-56 0.48
P2RX6_RAT P2rx6 P2X purinoceptor 6 2.408e-56 0.48
HSP7C_BOVIN HSPA8 Heat shock cognate 71 kDa protein 1.011e-55 0.44
WALK_STAAU walK Sensor protein kinase WalK 1.011e-55 0.44
ENPL_PIG HSP90B1 Endoplasmin 1.696e-55 0.44
SYS_ECOLI serS Serine--tRNA ligase 2.558e-55 0.44
ENPP1_RAT Enpp1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 6.547e-55 0.47
KMT5C_HUMAN KMT5C Histone-lysine N-methyltransferase KMT5C 7.269e-55 0.44
SETB1_HUMAN SETDB1 Histone-lysine N-methyltransferase SETDB1 7.269e-55 0.44
P2RY4_RAT P2ry4 P2Y purinoceptor 4 8.631e-55 0.46
RN5A_MOUSE Rnasel 2-5A-dependent ribonuclease 1.331e-54 0.39
SETD2_HUMAN SETD2 Histone-lysine N-methyltransferase SETD2 1.573e-54 0.43
METK2_RAT Mat2a S-adenosylmethionine synthase isoform type-2 2.735e-54 0.43
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 1.634e-53 0.64
MSHC_MYCTU mshC L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 1.668e-53 0.43
PARG_BOVIN PARG Poly(ADP-ribose) glycohydrolase 3.656e-53 0.39
ADA_BOVIN ADA Adenosine deaminase 1.157e-52 0.62
I6YFP0_MYCTU birA Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase) 4.819e-52 0.35
SYD_ECOLI aspS Aspartate--tRNA ligase 2.789e-51 0.41
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 8.778e-51 0.34
Q9HWG3_PSEAE pchD Pyochelin biosynthesis protein PchD 1.398e-50 0.40
ADCY2_RAT Adcy2 Adenylate cyclase type 2 3.839e-50 0.44
RNAS1_HUMAN RNASE1 Ribonuclease pancreatic 1.017e-49 0.34
RNAS2_HUMAN RNASE2 Non-secretory ribonuclease 1.017e-49 0.34
PANE_ECOLI panE 2-dehydropantoate 2-reductase 5.443e-49 0.31
RN5A_HUMAN RNASEL 2-5A-dependent ribonuclease 7.227e-49 0.39
ENTE_ECOLI entE Enterobactin synthase component E 8.02e-49 0.31
SYY_ECOLI tyrS Tyrosine--tRNA ligase 5.765e-48 0.38
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 3.01e-47 0.44
HARS1_HUMAN HARS1 Histidine--tRNA ligase, cytoplasmic 9.288e-47 0.37
Q4VQ11_PIG Adenosine receptor A1 1.187e-44 0.55
UBA7_HUMAN UBA7 Ubiquitin-like modifier-activating enzyme 7 3.774e-44 0.35
BIRA_ECOLI birA Bifunctional ligase/repressor BirA 1.756e-43 0.35
METK1_RAT Mat1a S-adenosylmethionine synthase isoform type-1 3.711e-42 0.36
ADCY5_RAT Adcy5 Adenylate cyclase type 5 1.732e-41 0.68
Q8TA74_HEMPU Ryanodine receptor 3.934e-40 0.33
S29A1_RAT Slc29a1 Equilibrative nucleoside transporter 1 9.023e-39 0.48
IF4E_MOUSE Eif4e Eukaryotic translation initiation factor 4E 1.089e-38 0.33
POLG_POL1M Genome polyprotein 4.536e-38 0.30
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 6.303e-38 0.43
S28A2_RAT Slc28a2 Sodium/nucleoside cotransporter 2 2.333e-36 0.29
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 2.619e-36 0.42
PYRF_YEAST URA3 Orotidine 5'-phosphate decarboxylase 3.788e-36 0.38
ISPE_ECOLI ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 3.875e-36 0.29
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 6.36e-36 0.36
ENTP1_BOVIN ENTPD1 Ectonucleoside triphosphate diphosphohydrolase 1 1.71e-35 0.28
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 2.005e-34 0.63
ANM7_HUMAN PRMT7 Protein arginine N-methyltransferase 7 2.601e-34 0.43
SYL_ECOLI leuS Leucine--tRNA ligase 5.293e-34 0.42
ADA_HUMAN ADA Adenosine deaminase 4.958e-33 0.60
Q9HX69_PSEAE rocR RocR 5.95e-33 0.34
GPR17_HUMAN GPR17 Uracil nucleotide/cysteinyl leukotriene receptor 7.448e-33 0.42
IUNH_CRIFA IUNH Inosine-uridine preferring nucleoside hydrolase 5.025e-32 0.33
O15727_TRYBB Inosine-adenosine-guanosine-nucleoside hydrolase 5.025e-32 0.33
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 2.118e-31 0.36
ADCY5_HUMAN ADCY5 Adenylate cyclase type 5 1.512e-30 0.28
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 4.851e-30 0.39
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 5.015e-30 0.48
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 2.986e-29 0.48
SUV91_HUMAN SUV39H1 Histone-lysine N-methyltransferase SUV39H1 1.385e-28 0.44
UBA6_HUMAN UBA6 Ubiquitin-like modifier-activating enzyme 6 2.3e-28 0.35
PUR6_CHICK AIRC Multifunctional protein ADE2 4.874e-28 0.34
AMPD1_RABIT AMPD1 AMP deaminase 1 7.994e-28 0.34
CDK12_HUMAN CDK12 Cyclin-dependent kinase 12 2.247e-27 0.34
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 8.491e-27 0.45
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 9.136e-27 0.74
SYMC_HUMAN MARS1 Methionine--tRNA ligase, cytoplasmic 1.182e-26 0.42
AA2AR_MOUSE Adora2a Adenosine receptor A2a 1.283e-26 0.30
MGMT_HUMAN MGMT Methylated-DNA--protein-cysteine methyltransferase 1.646e-26 0.35
P2RX4_RAT P2rx4 P2X purinoceptor 4 4.81e-26 0.48
AA1R_BOVIN ADORA1 Adenosine receptor A1 7.719e-26 0.74
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 2.453e-25 0.49
NNMT_HUMAN NNMT Nicotinamide N-methyltransferase 3.051e-25 0.34
SYI_ECOLI ileS Isoleucine--tRNA ligase 4.411e-25 0.40
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 5.693e-25 0.45
BPL1_HUMAN HLCS Biotin--protein ligase 1.533e-24 0.35
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 2.52e-24 0.48
PARG_HUMAN PARG Poly(ADP-ribose) glycohydrolase 3.022e-24 0.39
PANC_MYCTU panC Pantothenate synthetase 3.943e-24 0.44
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 5.682e-24 0.44
Q3ZDS5_9HEPC NS5B 1.069e-23 0.29
HEXB_HUMAN HEXB Beta-hexosaminidase subunit beta 1.114e-23 0.29
KITH_RAT Tk1 Thymidine kinase, cytosolic 1.551e-22 0.36
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1.666e-22 0.47
P2RX1_RAT P2rx1 P2X purinoceptor 1 6.553e-22 0.46
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 8.283e-22 0.51
DCAM_RAT Amd1 S-adenosylmethionine decarboxylase proenzyme 2.303e-21 0.51
KITH_VZVD TK Thymidine kinase 3.057e-21 0.32
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 6.242e-20 0.33
HEXA_HUMAN HEXA Beta-hexosaminidase subunit alpha 2.375e-18 0.29
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 4.377e-18 0.45
EZH1_HUMAN EZH1 Histone-lysine N-methyltransferase EZH1 1.243e-17 0.44
B4EH87_BURCJ Lectin 1.11e-16 0.32
5NTD_HUMAN NT5E 5'-nucleotidase 2.22e-16 0.47
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 9.992e-16 0.33
A0A0E7NXW5_STAAU birA Bifunctional ligase/repressor BirA 1.11e-15 0.35
SYTC_HUMAN TARS1 Threonine--tRNA ligase 1, cytoplasmic 1.221e-15 0.41
OGA_HUMAN OGA Protein O-GlcNAcase 5.884e-15 0.32
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 2.542e-14 0.44
AA1R_MOUSE Adora1 Adenosine receptor A1 2.931e-14 0.53
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 4.874e-14 0.42
KITH_HUMAN TK1 Thymidine kinase, cytosolic 5.551e-14 0.33
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 5.74e-14 0.48
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 1.239e-13 0.41
OGA_RAT Oga Protein O-GlcNAcase 3.084e-13 0.29
RAB7A_HUMAN RAB7A Ras-related protein Rab-7a 3.427e-13 0.42
CD69_HUMAN CD69 Early activation antigen CD69 3.773e-13 0.32
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 3.773e-13 0.32
ADH1A_HUMAN ADH1A Alcohol dehydrogenase 1A 4.547e-13 0.35
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 4.751e-13 0.42
HPPK_ECOLI folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 6.268e-13 0.38
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 7.736e-13 0.32
KAPCA_HUMAN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 1.146e-12 0.40
CCNK_HUMAN CCNK Cyclin-K 1.714e-12 0.34
AA3R_MOUSE Adora3 Adenosine receptor A3 2.783e-12 0.31
KMT2A_HUMAN KMT2A Histone-lysine N-methyltransferase 2A 4.94e-12 0.44
P2RX2_RAT P2rx2 P2X purinoceptor 2 1.161e-11 0.48
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 1.246e-11 0.45
ADK_RAT Adk Adenosine kinase 1.399e-11 0.55
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 6.023e-11 0.29
E1BN64_BOVIN PDE3B Phosphodiesterase 3.596e-10 0.34
LEG1_HUMAN LGALS1 Galectin-1 5.371e-10 0.28
TYPH_HUMAN TYMP Thymidine phosphorylase 5.714e-10 0.34
INMT_HUMAN INMT Indolethylamine N-methyltransferase 6.069e-10 0.44
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 9.827e-10 0.39
DCPS_HUMAN DCPS m7GpppX diphosphatase 1.145e-09 0.41
DPOLB_HUMAN POLB DNA polymerase beta 1.165e-09 0.31
M9TGV3_MYCTX inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 1.707e-09 0.32
5NTD_RAT Nt5e 5'-nucleotidase 1.778e-09 0.47
P2Y12_RAT P2ry12 P2Y purinoceptor 12 5.797e-09 0.48
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 1.315e-08 0.44
Q9Y0I0_9TRYP AT1 Adenosine transporter 1 1.557e-08 0.39
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 2.138e-08 0.33
SYT_YERPE thrS Threonine--tRNA ligase 3.442e-08 0.41
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 3.495e-08 0.47
LEG3_HUMAN LGALS3 Galectin-3 5.537e-08 0.28
EZH2_HUMAN EZH2 Histone-lysine N-methyltransferase EZH2 5.666e-08 0.44
ENPL_CANLF HSP90B1 Endoplasmin 7.105e-08 0.44
O39930_9HEPC NS5b RNA-directed RNA polymerase 1.123e-07 0.33
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.689e-07 0.34
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 2.815e-07 0.45
LUCI_AQULA Luciferin 4-monooxygenase 4.503e-07 0.35
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 4.858e-07 0.34
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 5.266e-07 0.34
DNLJ_STAAU ligA DNA ligase 5.605e-07 0.64
PNPH_HUMAN PNP Purine nucleoside phosphorylase 7.44e-07 0.43
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 1.292e-06 0.45
SMYD2_HUMAN SMYD2 N-lysine methyltransferase SMYD2 2.098e-06 0.44
Q56950_YERPE ybtE Salicyl-AMP ligase YbtE 3.423e-06 0.40
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 3.629e-06 0.68
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 4.003e-06 0.30
HPRT_HUMAN HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 4.055e-06 0.44

Fluvastatin

HMDH_RAT Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2.782e-259 1.00
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 5.021e-213 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.2713 1.00
HMDH_MOUSE Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 7.917e-64 0.41
HMDH_PIG HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 5.765e-28 0.45
FABP4_RAT Fabp4 Fatty acid-binding protein, adipocyte 2.847e-23 0.29
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 3.664e-15 0.45
PDE6D_HUMAN PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 3.099e-12 0.45
AK1A1_HUMAN AKR1A1 Aldo-keto reductase family 1 member A1 1.38e-09 0.32
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 2.567e-07 0.30
CENPE_HUMAN CENPE Centromere-associated protein E 3.098e-07 0.31
PD2R2_MOUSE Ptgdr2 Prostaglandin D2 receptor 2 3.431e-07 0.32
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 1.074e-06 0.34
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 1.363e-06 0.30
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.827e-06 0.29
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 4.204e-06 0.31
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 4.596e-06 0.29
APJ_HUMAN APLNR Apelin receptor 6.947e-06 0.30

Rosuvastatin

HMDH_RAT Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2.473e-253 1.00
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 9.2e-194 1.00
PDE6D_HUMAN PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 3.215e-07 1.00
HMDH_MOUSE Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2.156e-62 0.41
HMDH_PIG HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2.025e-20 0.33
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 4.877e-07 0.33

Atorvastatin

HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 8.256e-222 1.00
HMDH_PIG HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 5.121e-61 1.00
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 1.472e-31 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.9174 1.00
HMDH_RAT Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.93e-263 0.72
HMDH_MOUSE Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 7.788e-49 0.32
CCR3_MACFA CCR3 C-C chemokine receptor type 3 7.142e-37 0.29
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 2.116e-25 0.34
PRIO_SHEEP PRNP Major prion protein 3.192e-24 0.31
PDE6D_HUMAN PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 3.392e-21 0.76
MMP3_HUMAN MMP3 Stromelysin-1 4.996e-15 0.37
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 4.744e-13 0.32
APJ_HUMAN APLNR Apelin receptor 4.948e-11 0.30
Q6DMN0_TOXGO CPL Cathepsin L 2.659e-10 0.30
GALR1_RAT Galr1 Galanin receptor type 1 4.325e-10 0.29
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 5.13e-10 0.31
MMP12_HUMAN MMP12 Macrophage metalloelastase 2.202e-09 0.34
CAC1H_HUMAN CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H 2.355e-09 0.31
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 2.563e-09 0.30
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 3.244e-09 0.28
VE1_HPV11 E1 Replication protein E1 5.158e-09 0.31
ITB7_HUMAN ITGB7 Integrin beta-7 1.742e-08 0.32
MMP2_HUMAN MMP2 72 kDa type IV collagenase 2.33e-08 0.37
CASP1_MOUSE Casp1 Caspase-1 4.167e-08 0.35
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 1.703e-07 0.31
MMP1_HUMAN MMP1 Interstitial collagenase 2.191e-07 0.37
GATA4_MOUSE Gata4 Transcription factor GATA-4 2.729e-07 0.30
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 2.729e-07 0.30
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 3.864e-07 0.30
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 4.221e-07 0.29
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 6.705e-07 0.31
CTNB1_HUMAN CTNNB1 Catenin beta-1 1.499e-06 0.29
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 3.31e-06 0.28
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 3.488e-06 0.29
ANO1_HUMAN ANO1 Anoctamin-1 5.635e-06 0.30

Atazanavir

Q72874_9HIV1 pol Pol polyprotein 1.179e-184 1.00
Q9YQ12_9HIV1 protease Protease 1.724e-147 1.00
O90781_9PLVG HIV-1 protease HIV-1 protease 2.72e-133 1.00
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 1.266e-14 1.00
Q82134_9DELA prt Protease 1.317e-146 0.36
POL_HV1A2 gag-pol Gag-Pol polyprotein 1.699e-100 0.32
Q82323_9DELA Protease 1.263e-94 0.31
PLM1_PLAFA Plasmepsin-1 1.952e-74 0.40
RENI_HUMAN REN Renin 7.092e-62 0.38
CATL1_BOVIN CTSL Cathepsin L1 1.079e-58 0.36
PRO_HTL1A gag-pro Gag-Pro polyprotein 2.921e-54 0.31
CATD_HUMAN CTSD Cathepsin D 1.146e-46 0.58
PSA1_HUMAN PSMA1 Proteasome subunit alpha type-1 3.331e-45 0.37
PSA2_HUMAN PSMA2 Proteasome subunit alpha type-2 3.331e-45 0.37
PSA3_HUMAN PSMA3 Proteasome subunit alpha type-3 3.331e-45 0.37
PSA4_HUMAN PSMA4 Proteasome subunit alpha type-4 3.331e-45 0.37
PSA5_HUMAN PSMA5 Proteasome subunit alpha type-5 3.331e-45 0.37
PSA6_HUMAN PSMA6 Proteasome subunit alpha type-6 3.331e-45 0.37
PSA7_HUMAN PSMA7 Proteasome subunit alpha type-7 3.331e-45 0.37
PSB11_HUMAN PSMB11 Proteasome subunit beta type-11 3.331e-45 0.37
PSB3_HUMAN PSMB3 Proteasome subunit beta type-3 3.331e-45 0.37
PSB4_HUMAN PSMB4 Proteasome subunit beta type-4 3.331e-45 0.37
PSB6_HUMAN PSMB6 Proteasome subunit beta type-6 3.331e-45 0.37
PSB7_HUMAN PSMB7 Proteasome subunit beta type-7 3.331e-45 0.37
PSMA8_HUMAN PSMA8 Proteasome subunit alpha-type 8 3.331e-45 0.37
PLM2_PLAFA Plasmepsin-2 1.529e-44 0.40
PSB10_HUMAN PSMB10 Proteasome subunit beta type-10 9.438e-44 0.37
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 5.23e-37 0.37
CANX_CHICK Calpain-1 catalytic subunit 1.71e-35 0.28
PEPA_PIG PGA Pepsin A 3.294e-34 0.40
PEPC_HUMAN PGC Gastricsin 6.359e-32 0.40
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 3.612e-31 0.37
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 8.778e-31 0.37
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 7.189e-30 0.37
CATD_BOVIN CTSD Cathepsin D 8.551e-30 0.40
PEPT1_DERPT DERP1 Peptidase 1 1.17e-24 0.32
CARP_YEAST PEP4 Saccharopepsin 1.535e-24 0.30
PAPA1_CARPA Papain 6.042e-24 0.36
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 3.165e-23 0.32
UROK_RAT Plau Urokinase-type plasminogen activator 5.225e-23 0.28
Q3HTL5_PLAFA fp2B Falcipain 2B 7.318e-23 0.28
KLK5_HUMAN KLK5 Kallikrein-5 1.209e-21 0.39
Q4U254_9ENTO protease Protease 2.868e-21 0.40
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 6.747e-21 0.31
P88142_9HIV2 pol Pol polyprotein 2.843e-19 0.29
RENI_RAT Ren1 Renin 5.229e-19 0.34
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 1.022e-18 0.31
NK3R_CAVPO TACR3 Neuromedin-K receptor 9.992e-16 0.31
BACE1_HUMAN BACE1 Beta-secretase 1 1.221e-15 0.37
NK3R_HUMAN TACR3 Neuromedin-K receptor 1.044e-14 0.34
PTPRB_HUMAN PTPRB Receptor-type tyrosine-protein phosphatase beta 1.377e-14 0.32
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 2.587e-14 0.37
CBPA1_HUMAN CPA1 Carboxypeptidase A1 1.188e-13 0.29
UROK_MOUSE Plau Urokinase-type plasminogen activator 5.476e-13 0.28
CATF_HUMAN CTSF Cathepsin F 4.07e-12 0.29
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 1.822e-11 0.35
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 5.617e-11 0.33
RENI1_MOUSE Ren1 Renin-1 9.872e-11 0.29
CATB_HUMAN CTSB Cathepsin B 2.347e-10 0.37
APH1A_HUMAN APH1A Gamma-secretase subunit APH-1A 5.06e-10 0.43
APH1B_HUMAN APH1B Gamma-secretase subunit APH-1B 5.06e-10 0.43
NICA_HUMAN NCSTN Nicastrin 5.06e-10 0.43
PEN2_HUMAN PSENEN Gamma-secretase subunit PEN-2 5.109e-10 0.43
PSN2_HUMAN PSEN2 Presenilin-2 5.256e-10 0.43
CARP_RHICH Rhizopuspepsin 6.811e-10 0.31
POL_HV1BR gag-pol Gag-Pol polyprotein 9.521e-10 0.30
MMP3_HUMAN MMP3 Stromelysin-1 1.181e-09 0.32
GLNA_HUMAN GLUL Glutamine synthetase 1.206e-09 0.30
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 1.206e-09 0.30
PSN1_HUMAN PSEN1 Presenilin-1 1.265e-09 0.43
ECE1_RAT Ece1 Endothelin-converting enzyme 1 4.329e-09 0.29
NEP_HUMAN MME Neprilysin 8.465e-09 0.31
CATE_HUMAN CTSE Cathepsin E 8.732e-09 0.40
BACE2_HUMAN BACE2 Beta-secretase 2 8.769e-09 0.30
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 9.565e-09 0.38
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 1.877e-08 0.30
NK2R_MESAU TACR2 Substance-K receptor 1.994e-08 0.30
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 7.772e-08 0.32
LPXC_PSEAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.436e-07 0.33
CYSP_TRYCR Cruzipain 2.418e-07 0.32
Q95PM0_TRYBR rhodesain Cysteine protease 3.229e-07 0.30
MMP1_HUMAN MMP1 Interstitial collagenase 2.535e-06 0.32
NK3R_RAT Tacr3 Neuromedin-K receptor 3.536e-06 0.30
MMP2_HUMAN MMP2 72 kDa type IV collagenase 3.923e-06 0.31
FCER2_HUMAN FCER2 Low affinity immunoglobulin epsilon Fc receptor 7.219e-06 0.32
CAN1_RAT Capn1 Calpain-1 catalytic subunit 8.684e-06 0.28
Q9JN24_ECOLX def Peptide deformylase 9.831e-06 0.32

Dutasteride

S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 2.689e-180 1.00
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 3.001e-155 1.00
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 6.82e-11 1.00
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 2.98e-89 0.58
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 3.129e-48 0.64
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.171e-42 0.64
ANDR_RAT Ar Androgen receptor 1.894e-39 0.60
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 3.717e-22 0.29
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 2.036e-19 0.31
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 2.587e-19 0.30
GBRD_HUMAN GABRD Gamma-aminobutyric acid receptor subunit delta 3.331e-16 0.34
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.776e-15 0.32
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 4.932e-13 0.34
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 3.427e-10 0.32
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 8.359e-08 0.31
RXFP1_HUMAN RXFP1 Relaxin receptor 1 1.573e-07 0.29
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 6.037e-07 0.32
STS_HUMAN STS Steryl-sulfatase 6.898e-07 0.32
GBRA4_HUMAN GABRA4 Gamma-aminobutyric acid receptor subunit alpha-4 8.798e-07 0.34

Nifedipine

CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 4.582e-176 1.00
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.664e-150 1.00
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 1.17e-146 1.00
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 3.28e-71 1.00
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 4.448e-60 1.00
CAC1D_HUMAN CACNA1D Voltage-dependent L-type calcium channel subunit alpha-1D 2.015e-56 1.00
TRPA1_MOUSE Trpa1 Transient receptor potential cation channel subfamily A member 1 1.781e-53 1.00
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 1.089e-50 1.00
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.482e-43 1.00
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 1.318e-07 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 5.544e-06 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 6.14e-06 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.0008224 1.00
AA1R_RAT Adora1 Adenosine receptor A1 0.0008413 1.00
AA2AR_RAT Adora2a Adenosine receptor A2a 0.006536 1.00
ACES_ELEEL ache Acetylcholinesterase 0.007315 1.00
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 0.0238 1.00
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 0.5511 1.00
CHLE_HORSE BCHE Cholinesterase 0.6331 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.9572 1.00
AA1R_HUMAN ADORA1 Adenosine receptor A1 0.9937 1.00
S27A4_HUMAN SLC27A4 Long-chain fatty acid transport protein 4 3.788e-86 0.39
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 2.652e-55 0.38
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 6.593e-38 0.35
AMPN_RAT Anpep Aminopeptidase N 8.297e-37 0.29
SCMU_MYCTU Secreted chorismate mutase 1.195e-36 0.29
S29A1_RAT Slc29a1 Equilibrative nucleoside transporter 1 2.111e-36 0.45
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 2.207e-31 0.39
MCR_HUMAN NR3C2 Mineralocorticoid receptor 2.72e-30 0.57
COLA_CLOPE colA Collagenase ColA 1.334e-22 0.30
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 6.221e-22 0.43
HPPD_PIG HPD 4-hydroxyphenylpyruvate dioxygenase 7.617e-21 0.33
Q95MF8_PIG Sulfotransferase 1.039e-18 0.30
TLR4_MOUSE Tlr4 Toll-like receptor 4 3.512e-18 0.42
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 1.726e-17 0.35
Q03732_HBV HBcAg Capsid protein 2.22e-16 0.35
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 5.551e-16 0.43
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 2.109e-15 0.31
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 3.464e-14 0.33
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 2.708e-13 0.43
TNR16_HUMAN NGFR Tumor necrosis factor receptor superfamily member 16 6.449e-13 0.28
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 1.4e-12 0.31
CAC1S_RAT Cacna1s Voltage-dependent L-type calcium channel subunit alpha-1S 3.895e-12 0.47
RORA_HUMAN RORA Nuclear receptor ROR-alpha 9.518e-12 0.30
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 1.088e-11 0.37
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.47e-11 0.43
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 6.885e-11 0.34
ILVB_ARATH ALS Acetolactate synthase, chloroplastic 7.834e-11 0.31
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.986e-10 0.43
B4URF0_I33A0 Neuraminidase 6.69e-10 0.35
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.022e-09 0.43
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 1.165e-09 0.33
AROQ_STRCO aroQ 3-dehydroquinate dehydratase 1.231e-09 0.30
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 1.89e-09 0.33
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 2.734e-09 0.32
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 3.781e-09 0.31
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 1.028e-08 0.36
METC_ECOLI metC Cystathionine beta-lyase MetC 1.347e-08 0.34
SENP8_HUMAN SENP8 Sentrin-specific protease 8 1.45e-08 0.32
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 4.296e-08 0.43
SENP6_HUMAN SENP6 Sentrin-specific protease 6 4.363e-08 0.32
A3KMY8_BOVIN GUSB Beta-glucuronidase 1.59e-07 0.36
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 2.505e-07 0.36
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 4.188e-07 0.53
EST1_RABIT Liver carboxylesterase 1 4.983e-07 0.34
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 7.709e-07 0.53
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.668e-06 0.45
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 1.967e-06 0.33
SENP7_HUMAN SENP7 Sentrin-specific protease 7 2.079e-06 0.32
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 4.872e-06 0.33
USP_DROME usp Protein ultraspiracle 6.965e-06 0.32
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 7.687e-06 0.33

Isoprenaline

ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 6.57e-146 1.00
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 1.054e-77 1.00
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 2.492e-77 1.00
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 2.179e-74 1.00
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 4.057e-74 1.00
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 6.054e-63 1.00
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.619e-53 1.00
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 1.078e-51 1.00
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 2.219e-49 1.00
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 6.524e-44 1.00
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 5.116e-36 1.00
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 6.953e-35 1.00
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 1.375e-10 1.00
DRD4_HUMAN DRD4 D(4) dopamine receptor 0.04189 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.1061 1.00
ADA2A_MOUSE Adra2a Alpha-2A adrenergic receptor 3.487e-68 0.55
ADA2C_MOUSE Adra2c Alpha-2C adrenergic receptor 3.487e-68 0.55
Q06347_9HIV2 reverse transcriptase Reverse transcriptase 1.431e-47 0.38
ADRB3_MOUSE Adrb3 Beta-3 adrenergic receptor 1.122e-42 0.34
DNMT1_MOUSE Dnmt1 DNA (cytosine-5)-methyltransferase 1 3.682e-30 0.29
Q39829_SOYBN Lipoxygenase 3.022e-24 0.39
H9TVJ1_CHISP TyR1 3.516e-24 0.30
ARP19_RAT Arpp19 cAMP-regulated phosphoprotein 19 1.444e-23 0.29
G3HDX1_CRIGR Alpha-1B adrenergic receptor 2.751e-21 0.41
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 2.808e-18 0.39
TYRO_HUMAN TYR Tyrosinase 2.22e-15 0.33
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 8.66e-15 0.32
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.464e-14 0.69
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 2.335e-13 0.31
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 2.583e-13 0.33
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 5.167e-13 0.42
RNH1_HUMAN RNASEH1 Ribonuclease H1 8.722e-13 0.38
COMT_PIG COMT Catechol O-methyltransferase 3.598e-09 0.29
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 4.34e-09 0.69
Q964Q8_TRYCR SPPS Solanesyl diphosphate synthase 6.365e-09 0.30
Q49PX0_9POXV N1L N1L 1.083e-08 0.31
AOC3_HUMAN AOC3 Membrane primary amine oxidase 9.872e-08 0.34
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 6.427e-07 0.30
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.639e-06 0.39
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 7.376e-06 0.39

Bupropion

ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 5.357e-141 1.00
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 1.385e-136 1.00
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 7.854e-134 1.00
ACHA_HUMAN CHRNA1 Acetylcholine receptor subunit alpha 6.786e-117 1.00
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 2.758e-44 1.00
ACHA3_HUMAN CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 1.928e-41 1.00
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 7.315e-26 1.00
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 1.403e-24 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 5.242e-19 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 2.22e-14 1.00
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 7.655e-09 1.00
ITA5_HUMAN ITGA5 Integrin alpha-5 0.0001351 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.0004393 1.00
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 0.06538 1.00
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 3.463e-102 0.48
UREA_CANEN Urease 4.651e-40 0.38
C5ISA2_SHEEP TUBA4A Tubulin alpha chain 6.694e-38 0.30
PHO85_YEAST PHO85 Cyclin-dependent protein kinase PHO85 1.627e-37 0.30
G3V906_RAT Hcar1 Hydroxycarboxylic acid receptor 1 5.351e-37 0.29
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 6.933e-34 0.35
ECR_BOMMO EcR Ecdysone receptor 1.061e-33 0.43
USP_DROME usp Protein ultraspiracle 3.456e-32 0.43
PA2A1_ECHCA Acidic phospholipase A2 EC-I 1.52e-28 0.35
PA2B1_NAJME Basic phospholipase A2 1 1.52e-28 0.35
PA2BA_PROFL Basic phospholipase A2 PLA-A 1.52e-28 0.35
ECR_DROME EcR Ecdysone receptor 2.202e-26 0.43
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 8.043e-26 0.41
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 9.841e-25 0.30
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 2.555e-24 0.46
CDK1_YEAST CDC28 Cyclin-dependent kinase 1 3.794e-24 0.30
TBA_TRYCR Tubulin alpha chain 6.853e-24 0.38
Q9TU16_CANLF PTGER4 Prostaglandin E receptor 4 1.926e-23 0.29
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 2.545e-22 0.35
E3UJZ5_SPOLI Ecdysone receptor 7.091e-20 0.43
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 8.516e-20 0.37
PDS_SYNE7 pds 15-cis-phytoene desaturase 2.096e-19 0.34
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 5.224e-19 0.38
GABT_RAT Abat 4-aminobutyrate aminotransferase, mitochondrial 7.357e-19 0.41
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 6.347e-18 0.43
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 7.386e-18 0.38
KMO_RAT Kmo Kynurenine 3-monooxygenase 2.359e-17 0.43
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 2.873e-17 0.38
Q8MWR1_SPOFR USP Ultraspiracle protein 4.441e-16 0.30
Q8MWR2_SPOFR EcR Ecdysteroid receptor 4.441e-16 0.30
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 1.443e-15 0.30
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 1.443e-15 0.32
ACES_ANOGA Ace Acetylcholinesterase 1.676e-14 0.40
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 1.754e-14 0.34
GRM5_HUMAN GRM5 Metabotropic glutamate receptor 5 2.476e-14 0.38
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 8.671e-14 0.30
XPO1_HUMAN XPO1 Exportin-1 2.112e-13 0.34
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 2.586e-13 0.47
EIS_MYCTU eis N-acetyltransferase Eis 4.722e-13 0.33
PEPT1_DERPT DERP1 Peptidase 1 8.781e-13 0.30
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 1.018e-12 0.31
CATL2_HUMAN CTSV Cathepsin L2 4.404e-12 0.36
PSBA_MARPO psbA Photosystem II protein D1 1.859e-11 0.36
5HT1D_RAT Htr1d 5-hydroxytryptamine receptor 1D 2.374e-11 0.32
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 3.155e-11 0.29
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 7.798e-11 0.29
H9CNL0_SPOEX Ryanodien receptor 9.112e-11 0.29
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 1.613e-10 0.46
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 2.9e-10 0.38
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 5.188e-10 0.38
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 9.972e-10 0.48
S100B_HUMAN S100B Protein S100-B 1.087e-09 0.28
SL9A1_HUMAN SLC9A1 Sodium/hydrogen exchanger 1 1.519e-09 0.31
IL8_HUMAN CXCL8 Interleukin-8 1.978e-09 0.32
SCYD_MAGO7 SDH1 Scytalone dehydratase 2.577e-09 0.34
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 3.739e-09 0.36
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.111e-08 0.29
F264_HUMAN PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 2.169e-08 0.31
ABCC9_HUMAN ABCC9 ATP-binding cassette sub-family C member 9 2.384e-08 0.34
KCJ11_HUMAN KCNJ11 ATP-sensitive inward rectifier potassium channel 11 2.933e-08 0.36
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 3.632e-08 0.30
EST2_HUMAN CES2 Cocaine esterase 4.42e-08 0.31
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 4.79e-08 0.28
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 5.731e-08 0.31
PRIO_SHEEP PRNP Major prion protein 6.776e-08 0.37
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 8.759e-08 0.31
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 1.238e-07 0.30
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.609e-07 0.30
Q38C41_TRYB2 Phosphotransferase 1.734e-07 0.31
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.529e-07 0.35
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 3.771e-07 0.29
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 4.038e-07 0.36
Q8MTZ4_9TRYP PPase1 Vacuolar-type proton translocating pyrophosphatase 1 5.217e-07 0.30
LUCI_AQULA Luciferin 4-monooxygenase 5.803e-07 0.35
CAC1I_HUMAN CACNA1I Voltage-dependent T-type calcium channel subunit alpha-1I 7.368e-07 0.37
CLK2_MOUSE Clk2 Dual specificity protein kinase CLK2 7.564e-07 0.29
CLK4_MOUSE Clk4 Dual specificity protein kinase CLK4 7.564e-07 0.29
CNR2_HUMAN CNR2 Cannabinoid receptor 2 7.596e-07 0.37
TAAR1_RAT Taar1 Trace amine-associated receptor 1 8.336e-07 0.34
EST1_RABIT Liver carboxylesterase 1 1.002e-06 0.31
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 1.917e-06 0.31
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 2.358e-06 0.31
O61059_LEIME LmGT2 Glucose transporter 2.49e-06 0.32
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 2.78e-06 0.38
AGP1_YEAST AGP1 General amino acid permease AGP1 3.052e-06 0.31
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 3.603e-06 0.36
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 6.12e-06 0.31
CATB_HUMAN CTSB Cathepsin B 7.517e-06 0.36

Orlistat

ABD12_HUMAN ABHD12 Lysophosphatidylserine lipase ABHD12 2.9e-124 1.00
ABHGA_HUMAN ABHD16A Phosphatidylserine lipase ABHD16A 2.9e-124 1.00
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 1.195e-113 1.00
LIPP_HUMAN PNLIP Pancreatic triacylglycerol lipase 5.121e-61 1.00
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 5.442e-43 1.00
DGLB_HUMAN DAGLB Sn1-specific diacylglycerol lipase beta 2.191e-35 1.00
DGLA_MOUSE Dagla Sn1-specific diacylglycerol lipase alpha 1.645e-26 1.00
ABHD6_HUMAN ABHD6 Monoacylglycerol lipase ABHD6 1.584e-12 1.00
FAS_HUMAN FASN Fatty acid synthase 1.242e-05 1.00
CNR1_HUMAN CNR1 Cannabinoid receptor 1 0.00449 1.00
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 0.004684 1.00
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 0.008309 1.00
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 8.016e-45 0.35
LYPA2_HUMAN LYPLA2 Acyl-protein thioesterase 2 1.258e-27 0.36
LYPA1_HUMAN LYPLA1 Acyl-protein thioesterase 1 4.774e-25 0.36
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 6.474e-25 0.31
MPIP2_MOUSE Cdc25b M-phase inducer phosphatase 2 7.84e-23 0.31
ACPM_BOVIN NDUFAB1 Acyl carrier protein, mitochondrial 1.438e-21 0.32
NDUV1_BOVIN NDUFV1 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 1.438e-21 0.32
CLPP_STAA8 clpP ATP-dependent Clp protease proteolytic subunit 3.983e-19 0.30
ACLY_RAT Acly ATP-citrate synthase 2.22e-16 0.35
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 2.22e-16 0.36
KPCA_RAT Prkca Protein kinase C alpha type 3.22e-15 0.31
ADH1G_HUMAN ADH1C Alcohol dehydrogenase 1C 8.66e-14 0.34
Q6UB75_PIG Group VII phospholipase A2 2.562e-13 0.29
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 1.106e-12 0.36
LASR_PSEAE lasR Transcriptional activator protein LasR 3.244e-12 0.30
TRAR_RHIRD traR Transcriptional activator protein TraR 6.013e-11 0.28
ADH1B_HUMAN ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH1B 9.638e-11 0.34
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 1.416e-10 0.29
PA2G5_HUMAN PLA2G5 Calcium-dependent phospholipase A2 2.783e-10 0.29
LUXR_ALIFS luxR Transcriptional activator protein LuxR 6.396e-10 0.28
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 1.175e-08 0.36
CATB_BOVIN CTSB Cathepsin B 2.357e-08 0.29
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 7.748e-08 0.32
PA2G5_MOUSE Pla2g5 Calcium-dependent phospholipase A2 1.664e-07 0.29
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 2.645e-07 0.28
PA2GA_MOUSE Pla2g2a Phospholipase A2, membrane associated 6.83e-07 0.29
ADH1A_HUMAN ADH1A Alcohol dehydrogenase 1A 1.239e-06 0.34

Ouabain

AT1B3_RAT Atp1b3 Sodium/potassium-transporting ATPase subunit beta-3 2.9e-124 1.00
AT1A4_RAT Atp1a4 Sodium/potassium-transporting ATPase subunit alpha-4 5.128e-114 1.00
AT1B1_RAT Atp1b1 Sodium/potassium-transporting ATPase subunit beta-1 5.128e-114 1.00
AT1A3_RAT Atp1a3 Sodium/potassium-transporting ATPase subunit alpha-3 2.326e-91 1.00
AT1A2_RAT Atp1a2 Sodium/potassium-transporting ATPase subunit alpha-2 1.133e-82 1.00
AT1A1_RAT Atp1a1 Sodium/potassium-transporting ATPase subunit alpha-1 2.714e-79 1.00
KLF5_HUMAN KLF5 Krueppel-like factor 5 3.879e-12 1.00
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 7.033e-05 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.7197 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9999 1.00
NOTC1_MOUSE Notch1 Neurogenic locus notch homolog protein 1 5.745e-80 0.46
AT1A1_CANLF ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 4.439e-78 0.47
AT1A1_HUMAN ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 1.207e-69 0.44
AT1A1_PIG ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 2.457e-54 0.34
SO4C1_HUMAN SLCO4C1 Solute carrier organic anion transporter family member 4C1 8.579e-52 0.47
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 1.289e-19 0.44
NOTC1_HUMAN NOTCH1 Neurogenic locus notch homolog protein 1 3.331e-16 0.39
AT12A_HUMAN ATP12A Potassium-transporting ATPase alpha chain 2 6.747e-11 0.42
PAX8_HUMAN PAX8 Paired box protein Pax-8 1.052e-06 0.72

Bicalutamide

ANDR_RAT Ar Androgen receptor 2.957e-118 1.00
ANDR_HUMAN AR Androgen receptor 1.079e-93 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.01788 1.00
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 2.822e-109 0.47
RORG_MOUSE Rorc Nuclear receptor ROR-gamma 1.349e-31 0.38
MOGT2_MOUSE Mogat2 2-acylglycerol O-acyltransferase 2 1.196e-26 0.33
Q9NBD4_PLAFA Cysteine protease falcipain-2 2.728e-24 0.30
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 9.201e-24 0.47
RORG_HUMAN RORC Nuclear receptor ROR-gamma 1.59e-21 0.42
BLM_HUMAN BLM Bloom syndrome protein 2.862e-21 0.43
DHI1_MOUSE Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 7.595e-21 0.38
PRGR_RAT Pgr Progesterone receptor 4.887e-20 0.45
WRN_HUMAN WRN Werner syndrome ATP-dependent helicase 3.728e-19 0.29
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.11e-16 0.31
UT2_RAT Slc14a2 Urea transporter 2 4.441e-16 0.31
PYRD_RAT Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 7.772e-16 0.34
RORB_HUMAN RORB Nuclear receptor ROR-beta 1.099e-14 0.32
TRPV4_RAT Trpv4 Transient receptor potential cation channel subfamily V member 4 2.554e-14 0.33
PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 1.454e-13 0.34
MOGT2_HUMAN MOGAT2 2-acylglycerol O-acyltransferase 2 1.722e-13 0.33
RORA_HUMAN RORA Nuclear receptor ROR-alpha 2.374e-12 0.32
SCN9A_HUMAN SCN9A Sodium channel protein type 9 subunit alpha 2.638e-12 0.35
F261_HUMAN PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 3.127e-12 0.31
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 3.602e-12 0.35
KCJ11_HUMAN KCNJ11 ATP-sensitive inward rectifier potassium channel 11 6.532e-12 0.34
MCR_HUMAN NR3C2 Mineralocorticoid receptor 1.943e-11 0.34
UT1_RAT Slc14a1 Urea transporter 1 2.363e-11 0.31
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 4.284e-11 0.33
DHI1_HUMAN HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 4.484e-11 0.38
PRGR_HUMAN PGR Progesterone receptor 2.694e-10 0.43
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 6.731e-10 0.33
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 8.149e-10 0.31
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 8.45e-10 0.33
TRPV4_MOUSE Trpv4 Transient receptor potential cation channel subfamily V member 4 8.577e-10 0.28
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 1.382e-09 0.36
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 6.689e-09 0.42
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 2.243e-08 0.29
UBP47_HUMAN USP47 Ubiquitin carboxyl-terminal hydrolase 47 6.174e-08 0.29
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 7.595e-08 0.34
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 1.033e-07 0.34
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 2.041e-07 0.32
I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 2.089e-07 0.35
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 2.369e-07 0.42
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 3.811e-07 0.29
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 4.213e-07 0.32
SFRP1_HUMAN SFRP1 Secreted frizzled-related protein 1 4.386e-07 0.29
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 5.506e-07 0.33
Q9BRH5_HUMAN DGAT1 DGAT1 protein 8.619e-07 0.29
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 9.893e-07 0.34
SCYD_MAGO7 SDH1 Scytalone dehydratase 1.02e-06 0.29
CYNT_HELPY cynT Carbonic anhydrase 1.235e-06 0.29
NR1I2_HUMAN NR1I2 Nuclear receptor subfamily 1 group I member 2 1.717e-06 0.32
LGMN_HUMAN LGMN Legumain 2.232e-06 0.31
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 2.849e-06 0.29
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 2.859e-06 0.31
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 3.477e-06 0.28
CXCR2_HUMAN CXCR2 C-X-C chemokine receptor type 2 6.731e-06 0.33

Pioglitazone

CISD1_RAT Cisd1 CDGSH iron-sulfur domain-containing protein 1 1.153e-110 1.00
ABCBB_RAT Abcb11 Bile salt export pump 2.645e-55 1.00
ABCBB_HUMAN ABCB11 Bile salt export pump 4.629e-39 1.00
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.271e-33 1.00
CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 1.139e-30 1.00
PPARG_RAT Pparg Peroxisome proliferator-activated receptor gamma 8.832e-27 1.00
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 1.11e-16 1.00
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 2.946e-10 1.00
AOFB_RAT Maob Amine oxidase [flavin-containing] B 0.001369 1.00
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 0.01049 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 0.9134 1.00
MPC2_HUMAN MPC2 Mitochondrial pyruvate carrier 2 3.57e-93 0.69
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 1.628e-38 0.56
HST2_YEAST HST2 NAD-dependent protein deacetylase HST2 1.72e-19 0.31
HRH3_RAT Hrh3 Histamine H3 receptor 1.11e-16 0.42
PGDH_HUMAN HPGD 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 3.973e-13 0.54
A0A0Y9T855_PLABE DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 6.108e-13 0.28
A5K1N1_PLAVS Dihydroorotate dehydrogenase, mitochondrial, putative 6.108e-13 0.28
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 4.073e-11 0.30
Q690N0_BOVIN PGR Progesterone receptor 1.091e-06 0.54
ITA5_HUMAN ITGA5 Integrin alpha-5 1.871e-06 0.29
RORA_HUMAN RORA Nuclear receptor ROR-alpha 2.497e-06 0.31

Diphenylpyraline

SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 4.385e-102 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 9.627e-10 1.00
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 3.069e-73 0.63
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.456e-49 0.63
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 1.776e-39 0.34
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 8.341e-39 0.31
TYRP1_MOUSE Tyrp1 5,6-dihydroxyindole-2-carboxylic acid oxidase 2.145e-35 0.29
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 4.089e-33 0.36
Q9WTR4_RAT Slc6a2 Transporter 1.658e-32 0.54
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 4.161e-32 0.63
ACHP_LYMST Acetylcholine-binding protein 2.519e-30 0.45
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 1.499e-27 0.36
Q8WSF8_APLCA Soluble acetylcholine receptor 6.228e-27 0.33
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 3.585e-26 0.63
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 1.011e-22 0.36
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 9.45e-21 0.37
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 2.503e-20 0.31
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 4.444e-17 0.40
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 1.776e-15 0.29
NK1R_MOUSE Tacr1 Substance-P receptor 4.441e-15 0.29
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 3.553e-14 0.35
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 1.155e-13 0.40
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 8.229e-13 0.31
OPRX_HUMAN OPRL1 Nociceptin receptor 2.794e-12 0.33
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 4.279e-12 0.63
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 6.612e-12 0.49
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.258e-11 0.36
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.811e-11 0.31
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 4.839e-11 0.63
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.167e-10 0.63
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 2.37e-10 0.63
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 3.274e-10 0.36
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 5.862e-10 0.31
NK1R_RAT Tacr1 Substance-P receptor 1.165e-09 0.32
Q8WMX0_BOVIN Muscarinic receptor M1 1.243e-09 0.35
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.736e-09 0.63
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.872e-09 0.63
DRD5_HUMAN DRD5 D(1B) dopamine receptor 2.367e-09 0.36
ACHB2_RAT Chrnb2 Neuronal acetylcholine receptor subunit beta-2 2.393e-09 0.37
ANM8_HUMAN PRMT8 Protein arginine N-methyltransferase 8 3.413e-09 0.34
BLAB_AERHY cphA Metallo-beta-lactamase type 2 3.598e-09 0.29
ACHA4_RAT Chrna4 Neuronal acetylcholine receptor subunit alpha-4 4.14e-09 0.37
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.103e-08 0.63
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 2.301e-08 0.31
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.466e-08 0.63
HRH1_CAVPO HRH1 Histamine H1 receptor 5.683e-08 0.49
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 1.858e-07 0.35
Q63380_RAT NET Transporter 2.932e-07 0.31
NK1R_HUMAN TACR1 Substance-P receptor 4.514e-07 0.31
MRGX1_HUMAN MRGPRX1 Mas-related G-protein coupled receptor member X1 4.96e-07 0.29
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 5.732e-07 0.31
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 9.035e-07 0.36
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 1.068e-06 0.31
HRH1_HUMAN HRH1 Histamine H1 receptor 2.815e-06 0.63
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 3.213e-06 0.28
DRD1_RAT Drd1 D(1A) dopamine receptor 4.044e-06 0.32
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 5.177e-06 0.31
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 5.734e-06 0.29
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 8.612e-06 0.36

Levofloxacin

Q47245_ECOLX gyrA DNA gyrase subunit A 2.726e-89 1.00
C3SLN2_ECOLX gyrB DNA gyrase subunit B 2.83e-77 1.00
STE24_YEAST STE24 CAAX prenyl protease 1 2.428e-08 1.00
STRP_STRP1 ska Streptokinase A 2.689e-06 1.00
TRYP_PIG Trypsin 5.684e-05 1.00
ACEA_MYCTU icl Isocitrate lyase 7.603e-72 0.40
VATB2_HUMAN ATP6V1B2 V-type proton ATPase subunit B, brain isoform 1.89e-41 0.33
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 2.678e-22 0.84
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 2.996e-22 0.49
DPO3_BACSU polC DNA polymerase III PolC-type 3.278e-20 0.37
DPO1_THEAQ polA DNA polymerase I, thermostable 4.644e-17 0.34
PARC_STAAU parC DNA topoisomerase 4 subunit A 1.11e-16 0.45
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 2.665e-15 0.84
CNR2_RAT Cnr2 Cannabinoid receptor 2 3.388e-11 0.41
GYRA_MYCTU gyrA DNA gyrase subunit A 1.423e-08 0.45
GYRA_STAAU gyrA DNA gyrase subunit A 2.363e-07 0.42
WDR5_HUMAN WDR5 WD repeat-containing protein 5 6.609e-07 0.29
GYRA_ECOLI gyrA DNA gyrase subunit A 2.625e-06 0.42

Diclofenamide

CYNT_HELPY cynT Carbonic anhydrase 1.196e-81 1.00
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 5.252e-80 1.00
A6YCJ1_9METZ Astrosclerin-3 1.578e-78 1.00
B2V8E3_SULSY Carbonate dehydratase 1.635e-77 1.00
Q31FD6_HYDCU Carbonic anhydrase, alpha family 1.635e-77 1.00
CAH_METTE Carbonic anhydrase 1.506e-74 1.00
C0IX24_STYPI CA2 Carbonic anhydrase 2.36e-72 1.00
B5SU02_STYPI CA Alpha carbonic anhydrase 1.458e-69 1.00
Q5TU56_ANOGA 1272966 Carbonic anhydrase 1.373e-62 1.00
CAN_YEAST NCE103 Carbonic anhydrase 2.068e-58 1.00
CAH4_BOVIN CA4 Carbonic anhydrase 4 5.255e-53 1.00
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 8.898e-49 1.00
CAH15_MOUSE Ca15 Carbonic anhydrase 15 4.803e-46 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 4.92e-43 1.00
CAH6_HUMAN CA6 Carbonic anhydrase 6 8.797e-43 1.00
CAH1_HUMAN CA1 Carbonic anhydrase 1 6.167e-42 1.00
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.1e-41 1.00
Q6FTL6_CANGA NCE103 Carbonic anhydrase 8.848e-40 1.00
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 3.043e-37 1.00
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 3.58e-35 1.00
CAN_CANAL NCE103 Carbonic anhydrase 2.253e-33 1.00
CAH13_MOUSE Ca13 Carbonic anhydrase 13 7.672e-31 1.00
CAH9_HUMAN CA9 Carbonic anhydrase 9 2.804e-30 1.00
CAH7_HUMAN CA7 Carbonic anhydrase 7 8.521e-30 1.00
CAH12_HUMAN CA12 Carbonic anhydrase 12 9.68e-28 1.00
CAH4_HUMAN CA4 Carbonic anhydrase 4 8.242e-27 1.00
CAH14_HUMAN CA14 Carbonic anhydrase 14 9.199e-26 1.00
CAH13_HUMAN CA13 Carbonic anhydrase 13 1.078e-24 1.00
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 1.947e-20 1.00
CAH2_BOVIN CA2 Carbonic anhydrase 2 1.658e-52 0.54
CAH3_HUMAN CA3 Carbonic anhydrase 3 2.172e-30 0.41
PGES2_HUMAN PTGES2 Prostaglandin E synthase 2 1.676e-29 0.40
Q9HVB9_PSEAE Carbonic anhydrase 1.571e-21 0.34
CAH1_HORSE CA1 Carbonic anhydrase 1 1.11e-16 0.29
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 6.151e-14 0.34
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 2.975e-11 0.36
METC_ECOLI metC Cystathionine beta-lyase MetC 6.636e-09 0.35
O77078_PLAFA fabH Beta-ketoacyl-acyl carrier protein synthase III 1.322e-08 0.29
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 2.989e-08 0.36
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 9.396e-07 0.29
APEX1_HUMAN APEX1 DNA-(apurinic or apyrimidinic site) lyase 2.036e-06 0.58
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.849e-06 0.29

Sertraline

Q9WTR4_RAT Slc6a2 Transporter 7.078e-80 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 4.973e-60 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 9.576e-53 1.00
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 7.577e-49 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.737e-43 1.00
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 6.454e-41 1.00
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.851e-06 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 0.0002947 1.00
Q63380_RAT NET Transporter 0.0003039 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.002173 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.006662 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.007417 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.01743 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 0.04204 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 0.06101 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.06183 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.08091 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.1002 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.1054 1.00
MC5R_HUMAN MC5R Melanocortin receptor 5 0.1414 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.4144 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.5554 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.704 1.00
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 1.046e-73 0.39
SC6A4_MACMU SLC6A4 Sodium-dependent serotonin transporter 3.13e-63 0.33
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 9.927e-59 0.39
F1LNR9_RAT Slc6a2 Transporter 2.843e-54 0.31
Q7JHP9_MACMU SLC6A3 Transporter 2.623e-51 0.33
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 3.57e-28 0.32
KCNN1_HUMAN KCNN1 Small conductance calcium-activated potassium channel protein 1 4.226e-09 0.28
KCNN2_HUMAN KCNN2 Small conductance calcium-activated potassium channel protein 2 1.178e-07 0.28
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 1.422e-07 0.35

Cefadroxil

S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 2.714e-79 1.00
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 2.271e-54 1.00
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.118e-38 1.00
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 1.71e-81 0.44
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 2.973e-50 0.44
Q7DHH4_STAAU mecA MecA 5.94e-36 0.28
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 3.067e-33 0.65
CATL1_RAT Ctsl Cathepsin L1 3.177e-30 0.33
B2ZTR6_ACIBA Beta-lactamase 7.107e-24 0.38
D6NSM8_ACIBA ampC Beta-lactamase 7.107e-24 0.38
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 2.22e-16 0.31
A2RP81_CITFR blaPER-2 Beta-lactamase 2.788e-13 0.29
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 2.282e-12 0.42
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 1.059e-09 0.33
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 8.011e-09 0.35
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.316e-07 0.34
STRP_STRP1 ska Streptokinase A 1.539e-07 0.67
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 1.405e-06 0.67

Cloxacillin

A4ZYU9_ECOLX blaACC-4 Beta-lactamase 2.714e-79 1.00
Q3S5C3_SALNE sugE Efflux transporter 5.121e-61 1.00
Q48435_KLEPN bla LAT-2 Beta-lactamase 5.121e-61 1.00
GPBAR_RAT Gpbar1 G-protein coupled bile acid receptor 1 5.283e-49 0.41
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 3.32e-42 0.48
NCAP_I33A0 NP Nucleoprotein 1.705e-35 0.44
BLAB_BACCE Metallo-beta-lactamase type 2 1.082e-31 0.36
A2RP81_CITFR blaPER-2 Beta-lactamase 1.793e-18 0.41
5HT1D_RAT Htr1d 5-hydroxytryptamine receptor 1D 6.253e-11 0.32
Q7T1G6_DANRE trpn1 Ion channel NompC 7.996e-11 0.36
TRAP_STAAM traP Signal transduction protein TRAP 1.064e-08 0.29
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 1.717e-08 0.44
FFAR2_MOUSE Ffar2 Free fatty acid receptor 2 1.725e-08 0.32
GBRA5_HUMAN GABRA5 Gamma-aminobutyric acid receptor subunit alpha-5 8.84e-08 0.31
GATA4_MOUSE Gata4 Transcription factor GATA-4 1.317e-07 0.31
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 1.317e-07 0.31
AMPC_ECOLI ampC Beta-lactamase 6.523e-07 0.38

Econazole

CP121_MYCTU cyp121 Mycocyclosin synthase 2.714e-79 1.00
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 1.089e-50 1.00
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 4.629e-39 1.00
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.673e-35 1.00
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 1.273e-34 1.00
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 3.937e-30 1.00
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 2.783e-20 1.00
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 7.759e-13 1.00
Q690N0_BOVIN PGR Progesterone receptor 6.498e-12 1.00
I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 9.297e-12 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 6.447e-07 1.00
Q8IL32_PLAF7 Heat shock protein 90, putative 1.464e-06 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.795e-05 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.0001433 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.0003003 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.0007537 1.00
NK2R_HUMAN TACR2 Substance-K receptor 0.001219 1.00
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 0.001285 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 0.002212 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.00263 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.003922 1.00
DNAB_MYCTU dnaB Replicative DNA helicase 0.005376 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.01153 1.00
ANDR_RAT Ar Androgen receptor 0.01773 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 0.03766 1.00
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 0.05077 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.05186 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 0.05689 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.08765 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.1005 1.00
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 0.18 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.1886 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.2856 1.00
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 0.2982 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.3224 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.3568 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.4145 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 0.6417 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.7026 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.7054 1.00
OPRD_HUMAN OPRD1 Delta-type opioid receptor 0.7755 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.7837 1.00
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 0.789 1.00
DRD4_HUMAN DRD4 D(4) dopamine receptor 0.8162 1.00
NK1R_HUMAN TACR1 Substance-P receptor 0.8338 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.8459 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 0.947 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.9804 1.00
AA1R_HUMAN ADORA1 Adenosine receptor A1 0.9937 1.00
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 0.9981 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 0.9982 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 0.9986 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 1 1.00
HMOX1_RAT Hmox1 Heme oxygenase 1 1.388e-129 0.48
CP21A_HUMAN CYP21A2 Steroid 21-hydroxylase 2.044e-65 0.30
HMOX2_RAT Hmox2 Heme oxygenase 2 2.282e-61 0.48
A2TEF2_LEIIN CYP51 Putative lanosterol 14-alpha-demethylase 9.875e-56 0.41
CP11A_RAT Cyp11a1 Cholesterol side-chain cleavage enzyme, mitochondrial 1.433e-54 0.30
CP7A1_RAT Cyp7a1 Cytochrome P450 7A1 1.433e-54 0.30
CP51A_RAT Cyp51a1 Lanosterol 14-alpha demethylase 1.801e-52 0.30
CP74A_ARATH CYP74A Allene oxide synthase, chloroplastic 1.479e-48 0.58
THAS_RAT Tbxas1 Thromboxane-A synthase 4.055e-48 0.38
CP3A5_HUMAN CYP3A5 Cytochrome P450 3A5 1.317e-37 0.30
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 6.655e-37 0.49
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 6.718e-37 0.49
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 3.695e-30 0.41
HMOX1_HUMAN HMOX1 Heme oxygenase 1 2.077e-27 0.34
CP51_CANAL ERG11 Lanosterol 14-alpha demethylase 2.01e-25 0.41
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 4.144e-20 0.49
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 1.636e-19 0.30
CP19A_HUMAN CYP19A1 Aromatase 1.736e-17 0.72
CP19A_RAT Cyp19a1 Aromatase 3.28e-17 0.33
CPXA_PSEPU camC Camphor 5-monooxygenase 4.11e-17 0.33
LUXR_ALIFS luxR Transcriptional activator protein LuxR 1.554e-15 0.48
TRPC6_MOUSE Trpc6 Short transient receptor potential channel 6 1.232e-14 0.40
QPCT_HUMAN QPCT Glutaminyl-peptide cyclotransferase 1.319e-07 0.37
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1.323e-06 0.41
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 2.027e-06 0.41
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 2.049e-06 0.29
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 2.756e-06 0.30

Etidronic_acid

B1LRJ1_ECOSM traI Type IV secretion-like conjugative transfer relaxase protein TraI 4.448e-70 1.00
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 1.487e-37 0.36
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 4.395e-28 0.41
Q197X6_TOXGO FPPS Farnesyl diphosphate synthase 2.38e-23 0.31
GGPPS_HUMAN GGPS1 Geranylgeranyl pyrophosphate synthase 1.045e-13 0.35
Q8WS26_TRYCR Farnesyl diphosphate synthase 2.716e-10 0.35
IMPA1_BOVIN IMPA1 Inositol monophosphatase 1 2.795e-09 0.31
Q8ST54_TRYCR HK Phosphotransferase 1.02e-07 0.35

Papaverine

Q9XSW7_PIG Phosphodiesterase 5.121e-61 1.00
PDE10_HUMAN PDE10A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 1.848e-38 1.00
PDE3B_HUMAN PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase B 2.052e-30 1.00
PDE3A_HUMAN PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase A 3.507e-20 1.00
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 5.235e-09 1.00
PDE5A_HUMAN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 1.51e-06 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.002199 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.003606 1.00
DNAB_MYCTU dnaB Replicative DNA helicase 0.006506 1.00
PDE2A_HUMAN PDE2A cGMP-dependent 3',5'-cyclic phosphodiesterase 0.02351 1.00
RECA_MYCTU recA Protein RecA 0.06861 1.00
PDE10_RAT Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 0.3597 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.8967 1.00
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 2.781e-71 0.40
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 4.054e-52 0.35
Q8Z9J9_SALTI folA Dihydrofolate reductase 1.822e-47 0.47
DRTS_PLAFK Bifunctional dihydrofolate reductase-thymidylate synthase 8.161e-45 0.47
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 1.58e-44 0.47
LOLA_ECOLI lolA Outer-membrane lipoprotein carrier protein 1.071e-38 0.31
AHR_RAT Ahr Aryl hydrocarbon receptor 1.917e-37 0.30
DYR_LACLA folA Dihydrofolate reductase 3.869e-34 0.38
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 2.387e-31 0.35
DRTS_PLABA Bifunctional dihydrofolate reductase-thymidylate synthase 2.968e-29 0.47
DYR1_ECOLX dhfrI Dihydrofolate reductase type 1 5.906e-22 0.38
DYR_LACCA folA Dihydrofolate reductase 1.784e-21 0.47
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 2.992e-21 0.32
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 5.394e-20 0.32
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 5.468e-20 0.40
Q49PX0_9POXV N1L N1L 1.11e-16 0.33
DYR_NEIGO folA Dihydrofolate reductase 2.22e-16 0.47
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 1.166e-13 0.29
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 1.463e-13 0.33
HGF_HUMAN HGF Hepatocyte growth factor 3.23e-13 0.29
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 7.249e-13 0.40
Q81R22_BACAN dfrA Dihydrofolate reductase 7.636e-13 0.33
LYPA2_HUMAN LYPLA2 Acyl-protein thioesterase 2 1.108e-12 0.31
ASM_HUMAN SMPD1 Sphingomyelin phosphodiesterase 2.757e-12 0.30
DYR_BOVIN DHFR Dihydrofolate reductase 3.079e-12 0.30
DYR_CANAX DFR1 Dihydrofolate reductase 8.76e-12 0.40
LYPA1_HUMAN LYPLA1 Acyl-protein thioesterase 1 1.554e-11 0.31
DYR_ECOLI folA Dihydrofolate reductase 2.234e-11 0.33
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 6.852e-11 0.31
IBP5_HUMAN IGFBP5 Insulin-like growth factor-binding protein 5 2.084e-10 0.33
RNH1_HUMAN RNASEH1 Ribonuclease H1 3.807e-10 0.30
QPCTL_HUMAN QPCTL Glutaminyl-peptide cyclotransferase-like protein 5.61e-10 0.33
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 6.32e-10 0.29
Q9UUP5_PNEJI DHFR DHFR 6.557e-10 0.33
DYR_STAAU folA Dihydrofolate reductase 3.69e-09 0.33
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 1.107e-08 0.33
DYR_RAT Dhfr Dihydrofolate reductase 1.823e-08 0.40
DYR_PNECA Dihydrofolate reductase 1.838e-08 0.40
A4_HUMAN APP Amyloid-beta precursor protein 2.387e-08 0.39
TAU_BOVIN MAPT Microtubule-associated protein tau 2.422e-08 0.29
PGK1_HUMAN PGK1 Phosphoglycerate kinase 1 3.777e-08 0.30
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 4.555e-08 0.33
LUCI_PHOPE Luciferin 4-monooxygenase 5.727e-08 0.31
DRTS_TOXGO Bifunctional dihydrofolate reductase-thymidylate synthase 9.878e-08 0.40
Q9BPW0_HUMAN PPP5C Serine/threonine-protein phosphatase 1.647e-07 0.44
ACES_HUMAN ACHE Acetylcholinesterase 2.638e-07 0.43
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 2.68e-07 0.28
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 2.721e-07 0.40
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 4.766e-07 0.31
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 5.559e-07 0.31
TTHY_HUMAN TTR Transthyretin 6.061e-07 0.33
TNR1A_HUMAN TNFRSF1A Tumor necrosis factor receptor superfamily member 1A 8.494e-07 0.33
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 1.084e-06 0.29
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 1.201e-06 0.31
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 1.402e-06 0.47
Q9JKC1_RAT Bche Carboxylic ester hydrolase 1.803e-06 0.30
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 1.812e-06 0.29
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 2.071e-06 0.34
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.713e-06 0.37
COT2_HUMAN NR2F2 COUP transcription factor 2 2.801e-06 0.35
O30463_MYCAV folA Dihydrofolate reductase 4.868e-06 0.33

Terazosin

ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 4.802e-59 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 3.046e-50 1.00
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 8.626e-47 1.00
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 5.869e-33 1.00
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 5.87e-29 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 8.706e-29 1.00
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 3.753e-17 1.00
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 4.934e-11 1.00
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 4.52e-10 1.00
ADA2B_RAT Adra2b Alpha-2B adrenergic receptor 3.385e-09 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 5.041e-05 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.0008507 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.001067 1.00
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 2.122e-165 0.47
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 1.755e-158 0.46
CCR4_MOUSE Ccr4 C-C chemokine receptor type 4 7.78e-95 0.41
KMT5A_HUMAN KMT5A N-lysine methyltransferase KMT5A 7.827e-69 0.38
CASB_RAT Csn2 Beta-casein 8.96e-67 0.58
CFAD_HUMAN CFD Complement factor D 1.479e-61 0.47
ADA2A_PIG ADRA2A Alpha-2A adrenergic receptor 1.028e-46 0.58
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 2.038e-45 0.37
KCNQ3_RAT Kcnq3 Potassium voltage-gated channel subfamily KQT member 3 6.705e-36 0.28
KCNQ4_RAT Kcnq4 Potassium voltage-gated channel subfamily KQT member 4 6.705e-36 0.28
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 7.196e-33 0.43
PDE3B_HUMAN PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase B 3.757e-32 0.30
PI3R5_HUMAN PIK3R5 Phosphoinositide 3-kinase regulatory subunit 5 8.106e-26 0.37
KCNQ3_HUMAN KCNQ3 Potassium voltage-gated channel subfamily KQT member 3 2.922e-25 0.32
PDE3A_HUMAN PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase A 1.693e-23 0.31
KCNQ5_HUMAN KCNQ5 Potassium voltage-gated channel subfamily KQT member 5 4.035e-23 0.28
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 1.051e-22 0.33
SSR2_RAT Sstr2 Somatostatin receptor type 2 2.399e-21 0.31
SSR1_RAT Sstr1 Somatostatin receptor type 1 1.06e-18 0.32
KCNQ4_HUMAN KCNQ4 Potassium voltage-gated channel subfamily KQT member 4 6.375e-18 0.28
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 8.61e-18 0.33
PDE4B_RAT Pde4b cAMP-specific 3',5'-cyclic phosphodiesterase 4B 2.22e-16 0.39
5HT1B_GORGO HTR1B 5-hydroxytryptamine receptor 1B 1.998e-15 0.29
NEK2_HUMAN NEK2 Serine/threonine-protein kinase Nek2 6.328e-15 0.36
PDPK1_HUMAN PDPK1 3-phosphoinositide-dependent protein kinase 1 2.118e-12 0.40
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 8.649e-12 0.32
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 2.8e-11 0.33
GAK_HUMAN GAK Cyclin-G-associated kinase 1.591e-10 0.32
ERM_STREE erm rRNA adenine N-6-methyltransferase 2.791e-09 0.29
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.815e-09 0.58
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 1.378e-08 0.65
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.695e-08 0.58
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 2.293e-08 0.35
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 2.519e-08 0.35
Q53I59_TRYCR PDEC Phosphodiesterase 3.296e-08 0.29
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 3.617e-08 0.58
DYR_BOVIN DHFR Dihydrofolate reductase 1.28e-07 0.31
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 1.403e-07 0.31
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 2.272e-07 0.39
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 9.996e-07 0.32
PK3CD_MOUSE Pik3cd Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1.549e-06 0.29
ALBU_BOVIN ALB Serum albumin 1.944e-06 0.28
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 3.148e-06 0.35
CFAB_HUMAN CFB Complement factor B 3.463e-06 0.34
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 5.929e-06 0.34

Diazoxide

ABCC8_HUMAN ABCC8 ATP-binding cassette sub-family C member 8 2.35e-56 1.00
KCJ11_HUMAN KCNJ11 ATP-sensitive inward rectifier potassium channel 11 7.55e-15 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.6858 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.7197 1.00
ABCC8_RAT Abcc8 ATP-binding cassette sub-family C member 8 1.466e-131 0.61
NCLX_HUMAN SLC8B1 Mitochondrial sodium/calcium exchanger protein 8.333e-36 0.28
T1QYY3_9HIV1 int Integrase 9.723e-22 0.31
CXCR2_HUMAN CXCR2 C-X-C chemokine receptor type 2 5.464e-09 0.37
DHI1_MOUSE Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 6.812e-09 0.36
TAT_HV112 tat Protein Tat 6.072e-07 0.31
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 8.134e-07 0.33
NOX1_HUMAN NOX1 NADPH oxidase 1 9.45e-07 0.32

Oxybutynin

ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 5.717e-51 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 8.953e-51 1.00
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 4.734e-49 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 6.65e-49 1.00
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 4.338e-48 1.00
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 7.308e-47 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 8.109e-22 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 7.772e-16 1.00
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 5.382e-10 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.563e-05 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.006597 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.2601 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.3252 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.5156 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.8821 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.9594 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.9887 1.00
AMYP_RAT Amy2 Pancreatic alpha-amylase 2.986e-102 0.53
Q8WMX0_BOVIN Muscarinic receptor M1 2.223e-58 0.39
ABHDB_HUMAN ABHD11 Protein ABHD11 4.955e-20 0.32
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 2.22e-16 0.31
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 5.071e-11 0.29
ABHD6_HUMAN ABHD6 Monoacylglycerol lipase ABHD6 8.247e-11 0.29
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 8.086e-10 0.42
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.594e-08 0.30
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 7.847e-08 0.31
MEN1_HUMAN MEN1 Menin 8.66e-08 0.31
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 2.676e-06 0.32

Leflunomide

PYRD_RAT Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 2.59e-50 1.00
PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 1.012e-43 1.00
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.554e-15 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.0001305 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.01118 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.6815 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.9383 1.00
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 3.553e-126 0.41
RXFP1_HUMAN RXFP1 Relaxin receptor 1 1.556e-112 0.39
APOB_HUMAN APOB Apolipoprotein B-100 4.892e-109 0.37
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 6.311e-93 0.51
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 1.593e-92 0.37
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 9.678e-75 0.44
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 8.533e-68 0.56
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 3.113e-57 0.51
TMPS4_HUMAN TMPRSS4 Transmembrane protease serine 4 2.387e-51 0.35
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 6.514e-49 0.52
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 8.516e-47 0.36
RXFP2_HUMAN RXFP2 Relaxin receptor 2 3.2e-43 0.40
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 2.482e-42 0.52
S20A2_HUMAN SLC20A2 Sodium-dependent phosphate transporter 2 8.37e-41 0.32
TRPC1_HUMAN TRPC1 Short transient receptor potential channel 1 1.845e-39 0.34
STIM2_HUMAN STIM2 Stromal interaction molecule 2 2.83e-38 0.30
SRPK1_MOUSE Srpk1 SRSF protein kinase 1 6.694e-38 0.30
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 4.657e-35 0.36
ADRB2_MOUSE Adrb2 Beta-2 adrenergic receptor 4.514e-34 0.29
VGFR2_DANRE kdr Vascular endothelial growth factor receptor 2 1.471e-32 0.34
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 6.044e-32 0.49
PTGES_CANLF PTGES Prostaglandin E synthase 1.396e-31 0.31
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 7.146e-31 0.46
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 1.091e-30 0.52
EHMT2_MOUSE Ehmt2 Histone-lysine N-methyltransferase EHMT2 1.955e-30 0.38
SHH_MOUSE Shh Sonic hedgehog protein 4.693e-30 0.38
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 9.904e-29 0.46
TA2R8_HUMAN TAS2R8 Taste receptor type 2 member 8 1.33e-27 0.34
Q25615_ONCVO Chitinase 1.361e-27 0.33
S20A1_HUMAN SLC20A1 Sodium-dependent phosphate transporter 1 3.081e-26 0.32
JUN_HUMAN JUN Transcription factor AP-1 4.941e-26 0.42
PSBA_MARPO psbA Photosystem II protein D1 1.952e-25 0.50
PTGES_HUMAN PTGES Prostaglandin E synthase 7.305e-25 0.42
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 4.908e-24 0.40
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 8.894e-24 0.35
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 1.122e-23 0.49
SMO_MOUSE Smo Smoothened homolog 2.205e-23 0.37
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 5.911e-22 0.36
TRPV4_RAT Trpv4 Transient receptor potential cation channel subfamily V member 4 8.909e-22 0.44
TRPV4_MOUSE Trpv4 Transient receptor potential cation channel subfamily V member 4 3.379e-21 0.34
PSBA_SPIOL psbA Photosystem II protein D1 3.608e-21 0.50
LCK_HUMAN LCK Tyrosine-protein kinase Lck 6.125e-21 0.42
TIE2_HUMAN TEK Angiopoietin-1 receptor 8.448e-21 0.36
SORT_HUMAN SORT1 Sortilin 2.532e-20 0.38
LIPL_HUMAN LPL Lipoprotein lipase 6.697e-20 0.32
ACRO_HUMAN ACR Acrosin 8.345e-20 0.35
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 1.784e-19 0.46
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 7.04e-19 0.35
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 2.374e-18 0.52
ELOV6_HUMAN ELOVL6 Elongation of very long chain fatty acids protein 6 3.66e-18 0.32
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 5.442e-18 0.35
SMO_HUMAN SMO Smoothened homolog 7.12e-18 0.37
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 7.856e-18 0.45
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 9.058e-18 0.35
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 1.152e-17 0.35
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 1.469e-17 0.52
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 1.562e-17 0.38
PRIO_SHEEP PRNP Major prion protein 1.828e-17 0.30
TAAR1_RAT Taar1 Trace amine-associated receptor 1 1.11e-16 0.38
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 9.992e-16 0.38
HDAC4_HUMAN HDAC4 Histone deacetylase 4 1.11e-15 0.38
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 2.109e-15 0.29
NR1H4_HUMAN NR1H4 Bile acid receptor 3.109e-15 0.38
ANO1_HUMAN ANO1 Anoctamin-1 3.775e-15 0.36
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 4.33e-15 0.41
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 5.107e-15 0.38
BLK_HUMAN BLK Tyrosine-protein kinase Blk 5.329e-15 0.34
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.377e-14 0.35
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 1.821e-14 0.37
GATA4_MOUSE Gata4 Transcription factor GATA-4 2.165e-14 0.32
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 2.165e-14 0.32
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 3.164e-14 0.33
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 7.602e-13 0.31
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 4.883e-12 0.46
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 6.418e-12 0.43
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 7.505e-12 0.42
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 1.062e-11 0.38
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 1.332e-11 0.32
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 2.4e-11 0.43
MATK_HUMAN MATK Megakaryocyte-associated tyrosine-protein kinase 2.533e-11 0.29
FA12_HUMAN F12 Coagulation factor XII 3.443e-11 0.32
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 3.897e-11 0.38
DPEP1_HUMAN DPEP1 Dipeptidase 1 6.626e-11 0.29
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 8.191e-11 0.37
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 8.223e-11 0.34
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 1.076e-10 0.36
ELOV6_MOUSE Elovl6 Elongation of very long chain fatty acids protein 6 2.131e-10 0.30
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 4.894e-10 0.52
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 5.051e-10 0.32
TRPC3_HUMAN TRPC3 Short transient receptor potential channel 3 6.99e-10 0.34
CTNB1_HUMAN CTNNB1 Catenin beta-1 7.272e-10 0.36
PYRD_PLAF7 Dihydroorotate dehydrogenase (quinone), mitochondrial 1.087e-09 0.29
ELOV3_HUMAN ELOVL3 Elongation of very long chain fatty acids protein 3 1.117e-09 0.30
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 1.162e-09 0.33
TPA_HUMAN PLAT Tissue-type plasminogen activator 1.185e-09 0.34
AURKA_HUMAN AURKA Aurora kinase A 1.543e-09 0.41
BRSK1_HUMAN BRSK1 Serine/threonine-protein kinase BRSK1 1.646e-09 0.32
KS6A1_HUMAN RPS6KA1 Ribosomal protein S6 kinase alpha-1 2.596e-09 0.39
BACE2_RAT Bace2 Beta-secretase 2 3.598e-09 0.29
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 3.779e-09 0.34
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 3.854e-09 0.34
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 5.415e-09 0.31
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 6.379e-09 0.39
BTK_HUMAN BTK Tyrosine-protein kinase BTK 9.341e-09 0.41
PANC_MYCTU panC Pantothenate synthetase 1.031e-08 0.33
ECR_AEDAE EcR Ecdysone receptor 1.594e-08 0.30
NRAM2_HUMAN SLC11A2 Natural resistance-associated macrophage protein 2 1.606e-08 0.40
AURKB_HUMAN AURKB Aurora kinase B 1.685e-08 0.43
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 2.079e-08 0.34
TEC_HUMAN TEC Tyrosine-protein kinase Tec 2.257e-08 0.34
KCC2B_HUMAN CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta 2.269e-08 0.31
KC1G2_HUMAN CSNK1G2 Casein kinase I isoform gamma-2 2.337e-08 0.32
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 2.638e-08 0.31
TYSY_ECOLI thyA Thymidylate synthase 3.456e-08 0.38
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 4.699e-08 0.32
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 5.476e-08 0.32
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 5.536e-08 0.33
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 5.544e-08 0.36
NLK_HUMAN NLK Serine/threonine-protein kinase NLK 6.378e-08 0.30
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 6.536e-08 0.32
MARK3_HUMAN MARK3 MAP/microtubule affinity-regulating kinase 3 6.571e-08 0.32
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 8.238e-08 0.29
BACE2_HUMAN BACE2 Beta-secretase 2 9.764e-08 0.33
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 1.132e-07 0.31
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 1.172e-07 0.52
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 1.191e-07 0.32
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 1.323e-07 0.38
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 1.49e-07 0.32
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 1.514e-07 0.32
TRAR_RHIRD traR Transcriptional activator protein TraR 1.747e-07 0.28
MINK1_HUMAN MINK1 Misshapen-like kinase 1 1.868e-07 0.32
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 3.273e-07 0.32
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 3.311e-07 0.44
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 3.513e-07 0.29
KLF5_HUMAN KLF5 Krueppel-like factor 5 3.642e-07 0.31
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 4.595e-07 0.32
NPY5R_MOUSE Npy5r Neuropeptide Y receptor type 5 5.651e-07 0.31
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 6.337e-07 0.30
BACE1_HUMAN BACE1 Beta-secretase 1 6.895e-07 0.37
RORG_MOUSE Rorc Nuclear receptor ROR-gamma 7.681e-07 0.32
EST2_HUMAN CES2 Cocaine esterase 7.784e-07 0.35
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 8.055e-07 0.48
PLK3_HUMAN PLK3 Serine/threonine-protein kinase PLK3 8.463e-07 0.31
SCNAA_HUMAN SCN10A Sodium channel protein type 10 subunit alpha 8.525e-07 0.30
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 9.396e-07 0.29
V1AR_RAT Avpr1a Vasopressin V1a receptor 9.434e-07 0.31
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 1.061e-06 0.32
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.263e-06 0.32
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 1.382e-06 0.32
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 1.397e-06 0.39
PLCB_HUMAN AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 1.552e-06 0.31
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.599e-06 0.33
HIPK2_HUMAN HIPK2 Homeodomain-interacting protein kinase 2 1.641e-06 0.31
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 1.732e-06 0.30
XBP1_HUMAN XBP1 X-box-binding protein 1 2.111e-06 0.40
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 2.415e-06 0.39
Q8MWR1_SPOFR USP Ultraspiracle protein 2.536e-06 0.32
Q8MWR2_SPOFR EcR Ecdysteroid receptor 2.536e-06 0.32
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 2.554e-06 0.29
LDLR_HUMAN LDLR Low-density lipoprotein receptor 2.849e-06 0.29
SCAF_HCMVA UL80 Capsid scaffolding protein 2.969e-06 0.33
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 3.098e-06 0.32
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.272e-06 0.28
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 3.3e-06 0.32
TXK_HUMAN TXK Tyrosine-protein kinase TXK 3.445e-06 0.34
PLK4_HUMAN PLK4 Serine/threonine-protein kinase PLK4 4.354e-06 0.32
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 4.857e-06 0.35
LUCI_AQULA Luciferin 4-monooxygenase 5.02e-06 0.29
CRCM1_HUMAN ORAI1 Calcium release-activated calcium channel protein 1 5.212e-06 0.34
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 5.885e-06 0.32
KCC2G_HUMAN CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 6.195e-06 0.32
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 6.294e-06 0.33
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 6.433e-06 0.29
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 6.83e-06 0.48
FER_HUMAN FER Tyrosine-protein kinase Fer 6.89e-06 0.29
V2R_RAT Avpr2 Vasopressin V2 receptor 7.345e-06 0.31
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 8.465e-06 0.34
KC1G3_HUMAN CSNK1G3 Casein kinase I isoform gamma-3 9.092e-06 0.30
IL2_HUMAN IL2 Interleukin-2 9.348e-06 0.30
UROK_HUMAN PLAU Urokinase-type plasminogen activator 9.956e-06 0.40

Emedastine

HRH1_CAVPO HRH1 Histamine H1 receptor 2.348e-48 1.00
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 4.348e-71 0.38
HMOX2_RAT Hmox2 Heme oxygenase 2 9.74e-66 0.35
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 2.325e-65 0.38
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 4.107e-56 0.32
PDE6D_HUMAN PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 1.958e-41 0.41
HRH4_HUMAN HRH4 Histamine H4 receptor 6.429e-28 0.43
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 4.267e-26 0.52
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 6.757e-23 0.37
5HT3B_HUMAN HTR3B 5-hydroxytryptamine receptor 3B 5.223e-20 0.38
SOS1_HUMAN SOS1 Son of sevenless homolog 1 1.193e-19 0.31
HRH1_HUMAN HRH1 Histamine H1 receptor 2.455e-18 0.62
RENI_MACMU REN Renin 7.773e-18 0.28
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 1.174e-17 0.45
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 8.737e-14 0.36
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 1.606e-12 0.31
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 4.484e-12 0.43
CHKA_HUMAN CHKA Choline kinase alpha 4.487e-12 0.31
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 4.582e-12 0.52
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 8.356e-12 0.29
BKRB1_RAT Bdkrb1 B1 bradykinin receptor 5.341e-10 0.32
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 1.4e-09 0.32
5HT1D_PIG HTR1D 5-hydroxytryptamine receptor 1D 2.217e-09 0.36
HRH4_RAT Hrh4 Histamine H4 receptor 3.582e-09 0.30
PK3CA_MOUSE Pik3ca Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 2.518e-08 0.30
O97467_PLAFA ht1 Hexose transporter 1 7.386e-08 0.34
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.42e-07 0.43
HRH2_HUMAN HRH2 Histamine H2 receptor 2.458e-07 0.30
GRM2_HUMAN GRM2 Metabotropic glutamate receptor 2 2.614e-07 0.37
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 3.078e-07 0.34
O61059_LEIME LmGT2 Glucose transporter 4.596e-07 0.34
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.297e-06 0.52
PRIO_MESAU PRNP Major prion protein 2.185e-06 0.29
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 5.64e-06 0.34

Amiodarone

SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 6.524e-44 1.00
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.56e-29 1.00
ERG2_YEAST ERG2 C-8 sterol isomerase 1.445e-27 1.00
THA_HUMAN THRA Thyroid hormone receptor alpha 1.892e-13 1.00
THB_HUMAN THRB Thyroid hormone receptor beta 5.473e-11 1.00
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 2.504e-10 1.00
FDFT_HUMAN FDFT1 Squalene synthase 0.0001509 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.0004463 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.0004782 1.00
LEF_BACAN lef Lethal factor 0.001556 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.001867 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 0.001899 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.003124 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.003461 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 0.005393 1.00
CYSP_TRYCR Cruzipain 0.005709 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.008927 1.00
BKRB2_HUMAN BDKRB2 B2 bradykinin receptor 0.01089 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.02469 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.0324 1.00
NK2R_HUMAN TACR2 Substance-K receptor 0.04329 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.05289 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 0.07824 1.00
MC5R_HUMAN MC5R Melanocortin receptor 5 0.1414 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.1762 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.2876 1.00
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 0.4821 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.5148 1.00
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 0.5511 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.658 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.6614 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 0.7853 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.8119 1.00
DRD4_HUMAN DRD4 D(4) dopamine receptor 0.8162 1.00
OPRD_HUMAN OPRD1 Delta-type opioid receptor 0.8394 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.8796 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9343 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 0.9559 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 0.9621 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 0.9973 1.00
VKOR1_RAT Vkorc1 Vitamin K epoxide reductase complex subunit 1 6.361e-42 0.32
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 1.78e-34 0.43
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 1.468e-19 0.30
PTN1_RAT Ptpn1 Tyrosine-protein phosphatase non-receptor type 1 1.11e-16 0.34
TSPO_RAT Tspo Translocator protein 5.551e-16 0.31
AMYP_RAT Amy2 Pancreatic alpha-amylase 4.43e-14 0.31
PLM2_PLAFA Plasmepsin-2 5.017e-13 0.31
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 1.573e-12 0.43
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 8.321e-11 0.32
CHLE_HUMAN BCHE Cholinesterase 1.146e-10 0.43
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 8.917e-10 0.30
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 5.661e-09 0.45
ACES_RAT Ache Acetylcholinesterase 5.682e-09 0.37
ACES_HUMAN ACHE Acetylcholinesterase 7.239e-09 0.37
Q8WMX0_BOVIN Muscarinic receptor M1 8.526e-09 0.31
Q9JKC1_RAT Bche Carboxylic ester hydrolase 1.476e-08 0.36
BIRC5_HUMAN BIRC5 Baculoviral IAP repeat-containing protein 5 5.44e-08 0.53
TAAR1_RAT Taar1 Trace amine-associated receptor 1 2.851e-07 0.81
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 7.857e-07 0.43
NORA_STAAU norA Quinolone resistance protein NorA 1.134e-06 0.33
NR1H4_MOUSE Nr1h4 Bile acid receptor 5.037e-06 0.28
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 8.99e-06 0.29

Carvedilol

ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 3.966e-39 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 0.0005077 1.00
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 2.117e-86 0.46
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 2.342e-81 0.48
Q533H1_FELCA UTS2R Urotensin II receptor 9.086e-76 0.34
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 4.403e-53 0.52
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 4.195e-45 0.48
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.221e-44 0.70
Q5YLN7_CANLF SCN5A Voltage-gated sodium channel Nav1.5 cardiac isoform 9.991e-44 0.35
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.781e-42 0.59
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 4.631e-37 0.41
CASR_BOVIN CASR Extracellular calcium-sensing receptor 8.297e-37 0.29
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 2.755e-36 0.41
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 2.243e-32 0.41
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.122e-31 0.45
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.201e-31 0.41
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 2.236e-31 0.41
DNMT1_MOUSE Dnmt1 DNA (cytosine-5)-methyltransferase 1 1.245e-30 0.30
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 8.163e-30 0.37
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 5.995e-19 0.41
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 5.395e-18 0.37
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 1.404e-17 0.49
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 4.596e-17 0.34
CASR_HUMAN CASR Extracellular calcium-sensing receptor 1.11e-15 0.43
UR2R_HUMAN UTS2R Urotensin-2 receptor 9.215e-15 0.39
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.21e-14 0.37
ADRB2_MOUSE Adrb2 Beta-2 adrenergic receptor 3.137e-13 0.32
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 3.917e-13 0.30
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 9.102e-13 0.33
TBB3_HUMAN TUBB3 Tubulin beta-3 chain 2.757e-12 0.30
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.659e-11 0.38
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 3.435e-11 0.42
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.145e-10 0.45
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 1.309e-10 0.28
GBRA6_HUMAN GABRA6 Gamma-aminobutyric acid receptor subunit alpha-6 2.1e-08 0.30
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 7.934e-08 0.48
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 8.132e-08 0.33
TLR4_HUMAN TLR4 Toll-like receptor 4 1.184e-07 0.32
PTK6_HUMAN PTK6 Protein-tyrosine kinase 6 1.327e-07 0.33
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 2.077e-07 0.29
ALBU_HUMAN ALB Serum albumin 2.457e-07 0.31
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 3.222e-07 0.41
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 1.309e-06 0.33
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 3.105e-06 0.41
GBRA4_HUMAN GABRA4 Gamma-aminobutyric acid receptor subunit alpha-4 3.156e-06 0.30
DRD4_HUMAN DRD4 D(4) dopamine receptor 3.302e-06 0.46

Pimozide

SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.935e-37 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.407e-31 1.00
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 3.937e-30 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 3.306e-25 1.00
DRD2_BOVIN DRD2 D(2) dopamine receptor 3.406e-23 1.00
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 1.21e-18 1.00
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 4.088e-13 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 1.11e-12 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.201e-10 1.00
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 1.367e-08 1.00
OPRD_HUMAN OPRD1 Delta-type opioid receptor 2.12e-08 1.00
WDR48_HUMAN WDR48 WD repeat-containing protein 48 2.882e-08 1.00
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 4.014e-08 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.143e-07 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 1.21e-07 1.00
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.466e-07 1.00
XBP1_HUMAN XBP1 X-box-binding protein 1 0.000332 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.008377 1.00
HRH4_HUMAN HRH4 Histamine H4 receptor 0.1211 1.00
PLD1_RAT Pld1 Phospholipase D1 2.215e-171 0.61
PLD1_HUMAN PLD1 Phospholipase D1 4.217e-161 0.61
PLD2_HUMAN PLD2 Phospholipase D2 1.966e-152 0.61
CCR3_RAT Ccr3 C-C chemokine receptor type 3 3.889e-81 0.36
CCR3_MOUSE Ccr3 Probable C-C chemokine receptor type 3 4.901e-69 0.36
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 3.849e-58 0.52
OPRX_HUMAN OPRL1 Nociceptin receptor 9.145e-51 0.59
CALRL_HUMAN CALCRL Calcitonin gene-related peptide type 1 receptor 6.551e-49 0.42
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.862e-44 0.40
DRD2_MOUSE Drd2 D(2) dopamine receptor 1.061e-42 0.38
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.926e-41 0.40
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.681e-41 0.39
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 4.633e-40 0.38
O19067_PIG N-methyl-D-aspartate receptor 1.474e-39 0.31
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 1.333e-36 0.39
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 3.973e-35 0.49
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 6.228e-35 0.51
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.969e-33 0.66
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.495e-29 0.70
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 3.714e-28 0.41
PDE6D_HUMAN PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 2.609e-26 0.32
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.929e-25 0.49
DRD2_RAT Drd2 D(2) dopamine receptor 6.172e-25 0.58
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 8.057e-25 0.66
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.941e-24 0.46
5HT7R_MOUSE Htr7 5-hydroxytryptamine receptor 7 3.516e-24 0.30
US28_HCMVA US28 G-protein coupled receptor homolog US28 2.944e-23 0.34
CALCA_RAT Calca Calcitonin gene-related peptide 1 4.989e-23 0.28
DRD4_RAT Drd4 D(4) dopamine receptor 1.678e-22 0.43
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 2.097e-22 0.45
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 2.254e-21 0.39
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 3.093e-21 0.49
DRD5_HUMAN DRD5 D(1B) dopamine receptor 5.275e-21 0.45
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 1.999e-20 0.44
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 2.021e-20 0.31
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.18e-19 0.67
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 1.344e-19 0.49
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 3.539e-19 0.36
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 3.933e-19 0.37
Q63380_RAT NET Transporter 1.667e-18 0.37
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 2.643e-18 0.61
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 4.486e-18 0.31
DRD3_HUMAN DRD3 D(3) dopamine receptor 9.911e-18 0.70
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.11e-16 0.53
AKT2_HUMAN AKT2 RAC-beta serine/threonine-protein kinase 1.11e-16 0.48
Q9WTR4_RAT Slc6a2 Transporter 1.11e-16 0.37
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 1.11e-16 0.41
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 2.22e-16 0.61
HRH3_CAVPO HRH3 Histamine H3 receptor 3.331e-16 0.48
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 8.882e-16 0.39
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.421e-14 0.58
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.465e-14 0.70
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.577e-14 0.70
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 3.919e-14 0.36
HRH1_HUMAN HRH1 Histamine H1 receptor 3.941e-14 0.58
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 7.006e-14 0.49
DRD3_CHLAE DRD3 D(3) dopamine receptor 7.605e-14 0.51
CASB_RAT Csn2 Beta-casein 1.242e-13 0.30
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 3.922e-13 0.29
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 8.911e-13 0.36
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 9.552e-13 0.34
NK2R_HUMAN TACR2 Substance-K receptor 1.032e-12 0.51
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.228e-12 0.61
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.278e-12 0.39
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.28e-12 0.53
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.292e-12 0.70
HRH2_HUMAN HRH2 Histamine H2 receptor 1.389e-12 0.45
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 2.26e-12 0.49
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 3.548e-12 0.58
5HT3B_MOUSE Htr3b 5-hydroxytryptamine receptor 3B 4.959e-12 0.29
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 5.012e-12 0.31
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 7.115e-12 0.32
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 8.017e-12 0.29
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 8.521e-12 0.39
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 1.141e-11 0.30
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 5.357e-11 0.53
HRH1_CAVPO HRH1 Histamine H1 receptor 7.257e-11 0.45
DRD5_RAT Drd5 D(1B) dopamine receptor 8.853e-11 0.32
MC4R_HUMAN MC4R Melanocortin receptor 4 1.695e-10 0.34
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 1.805e-10 0.48
DRD1_RAT Drd1 D(1A) dopamine receptor 2.336e-10 0.38
DRD1_HUMAN DRD1 D(1A) dopamine receptor 2.35e-10 0.48
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 2.791e-10 0.39
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 2.876e-10 0.49
RMLC_MYCTO rmlC dTDP-4-dehydrorhamnose 3,5-epimerase 3.238e-10 0.30
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 5.454e-10 0.58
CALRL_RAT Calcrl Calcitonin gene-related peptide type 1 receptor 6.557e-10 0.33
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 9.979e-10 0.33
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 1.103e-09 0.58
AKT3_HUMAN AKT3 RAC-gamma serine/threonine-protein kinase 1.153e-09 0.43
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 1.28e-09 0.50
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 3.219e-09 0.58
DRD2_CHLAE DRD2 D(2) dopamine receptor 8.733e-09 0.51
V1AR_MOUSE Avpr1a Vasopressin V1a receptor 2.359e-08 0.41
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 2.799e-08 0.49
CATS_HUMAN CTSS Cathepsin S 3.204e-08 0.43
LEF_BACAN lef Lethal factor 6.502e-08 0.32
ACHP_LYMST Acetylcholine-binding protein 8.736e-08 0.30
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 8.812e-08 0.33
VKOR1_RAT Vkorc1 Vitamin K epoxide reductase complex subunit 1 1.155e-07 0.31
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 4.055e-07 0.29
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 5.094e-07 0.32
PAX8_HUMAN PAX8 Paired box protein Pax-8 7.028e-07 0.44
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 7.045e-07 0.37
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 7.436e-07 0.58
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 8.263e-07 0.58
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.056e-06 0.31
NK1R_HUMAN TACR1 Substance-P receptor 1.075e-06 0.45
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 1.578e-06 0.37
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.699e-06 0.36
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 2.051e-06 0.49
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 2.71e-06 0.49
RAMP1_HUMAN RAMP1 Receptor activity-modifying protein 1 3.37e-06 0.38
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 3.91e-06 0.29
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 3.974e-06 0.49
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 4.204e-06 0.33
OXDA_PIG DAO D-amino-acid oxidase 4.387e-06 0.31
HRH1_RAT Hrh1 Histamine H1 receptor 5.606e-06 0.32
DRD1_MOUSE Drd1 D(1A) dopamine receptor 7.11e-06 0.31
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 7.564e-06 0.58

Primaquine

PERL_BOVIN LPO Lactoperoxidase 3.937e-30 1.00
CASP6_HUMAN CASP6 Caspase-6 1.925e-06 1.00
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 3.75e-06 1.00
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 6.485e-06 1.00
PERM_HUMAN MPO Myeloperoxidase 0.0001999 1.00
RECA_MYCTU recA Protein RecA 0.0004927 1.00
DNAB_MYCTU dnaB Replicative DNA helicase 0.0008604 1.00
CASP7_HUMAN CASP7 Caspase-7 0.003257 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.501 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.5147 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.9982 1.00
S40A1_HUMAN SLC40A1 Solute carrier family 40 member 1 1.968e-41 0.48
Q9NAW2_PLAFA Cysteine proteinase falcipain 2a 3.824e-40 0.32
MECP2_HUMAN MECP2 Methyl-CpG-binding protein 2 2.776e-23 0.37
HASP_HUMAN HASPIN Serine/threonine-protein kinase haspin 1.08e-21 0.31
IKBA_HUMAN NFKBIA NF-kappa-B inhibitor alpha 4.416e-20 0.45
RBP_CHICK Riboflavin-binding protein 5.429e-20 0.32
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 9.187e-18 0.33
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 5.474e-17 0.30
PDE4C_HUMAN PDE4C cAMP-specific 3',5'-cyclic phosphodiesterase 4C 2.22e-16 0.37
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 2.101e-11 0.44
HRP1_PLAFA Histidine-rich protein PFHRP-II 7.18e-10 0.66
PDE4A_HUMAN PDE4A cAMP-specific 3',5'-cyclic phosphodiesterase 4A 1.486e-07 0.37
TF65_HUMAN RELA Transcription factor p65 2.636e-07 0.45
PLM1_PLAFA Plasmepsin-1 3.894e-07 0.43
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 7.633e-07 0.32
S10A4_HUMAN S100A4 Protein S100-A4 7.758e-07 0.46
BXA1_CLOBO botA Botulinum neurotoxin type A 9.613e-07 0.33
DYR1_ECOLX dhfrI Dihydrofolate reductase type 1 2.577e-06 0.33
NSD2_HUMAN NSD2 Histone-lysine N-methyltransferase NSD2 3.126e-06 0.60
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 6.855e-06 0.37
STABP_HUMAN STAMBP STAM-binding protein 8.994e-06 0.29

Chlorpheniramine

HRH1_CAVPO HRH1 Histamine H1 receptor 1.716e-29 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.124e-19 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 5.383e-17 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 6.495e-14 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 2.191e-11 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.225e-10 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.268e-10 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 5.47e-08 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.651e-07 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 3.331e-07 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.967e-06 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 5.585e-06 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 7.312e-06 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.0001255 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.002717 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.007421 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.07775 1.00
UR2R_HUMAN UTS2R Urotensin-2 receptor 1.027e-79 0.46
PRIO_MOUSE Prnp Major prion protein 3.875e-36 0.29
HRH1_RAT Hrh1 Histamine H1 receptor 4.632e-35 0.62
US28_HCMVA US28 G-protein coupled receptor homolog US28 3.505e-21 0.30
CALM_BOVIN CALM Calmodulin 1.861e-20 0.29
HRH3_CAVPO HRH3 Histamine H3 receptor 2.239e-18 0.62
DPOL_HHV1K DNA polymerase catalytic subunit 2.301e-18 0.29
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 2.318e-12 0.29
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 3.028e-12 0.30
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 9.7e-12 0.29
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 9.7e-12 0.29
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 9.909e-12 0.30
ANM1_RAT Prmt1 Protein arginine N-methyltransferase 1 1.23e-11 0.28
FFAR2_HUMAN FFAR2 Free fatty acid receptor 2 2.249e-11 0.38
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 1.105e-10 0.29
GPR39_MOUSE Gpr39 G-protein coupled receptor 39 3.261e-10 0.32
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 9.827e-10 0.39
PPO1_AGABI PPO1 Polyphenol oxidase 1 2.039e-09 0.29
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 3.598e-09 0.29
CALM1_HUMAN CALM1 Calmodulin-1 3.985e-08 0.29
FFAR2_MOUSE Ffar2 Free fatty acid receptor 2 1.365e-07 0.28
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 1.612e-07 0.31
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 2.22e-07 0.33
VKOR1_RAT Vkorc1 Vitamin K epoxide reductase complex subunit 1 2.38e-07 0.30
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 3.012e-07 0.31
CP19A_RAT Cyp19a1 Aromatase 3.182e-07 0.33
TYTR_TRYBB TPR Trypanothione reductase 3.912e-07 0.33
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 7.406e-07 0.30
DXR_ECOLI dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3.496e-06 0.32
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 6.522e-06 0.33
DPOL_VACCW POL DNA polymerase 7.85e-06 0.28
GPR39_HUMAN GPR39 G-protein coupled receptor 39 9.607e-06 0.32

Norfloxacin

PARC_STAAU parC DNA topoisomerase 4 subunit A 1.517e-27 1.00
ACEA_MYCTU icl Isocitrate lyase 3.75e-92 0.67
GLYCP_NIPAV G Glycoprotein G 1.039e-84 0.49
VATB2_HUMAN ATP6V1B2 V-type proton ATPase subunit B, brain isoform 3.352e-80 0.64
Q47245_ECOLX gyrA DNA gyrase subunit A 2.092e-68 0.67
C3SLN2_ECOLX gyrB DNA gyrase subunit B 3.181e-59 0.67
DPO3_BACSU polC DNA polymerase III PolC-type 1.856e-30 0.51
Q76353_9HIV1 Integrase 7.934e-30 0.43
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 4.184e-19 0.42
Q7ZJM1_9HIV1 pol Integrase 9.992e-16 0.43
DPO1_THEAQ polA DNA polymerase I, thermostable 2.442e-15 0.31
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.548e-11 0.36
PARE_STAAU parE DNA topoisomerase 4 subunit B 1.358e-09 0.67
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 2.37e-09 0.33
1433G_HUMAN YWHAG 14-3-3 protein gamma 3.044e-09 0.33
GYRA_ECOLI gyrA DNA gyrase subunit A 6.847e-08 0.67
GYRA_MYCTU gyrA DNA gyrase subunit A 2.395e-07 0.38
GATA4_MOUSE Gata4 Transcription factor GATA-4 3.977e-07 0.29
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 3.977e-07 0.29
GYRA_STAAU gyrA DNA gyrase subunit A 7.07e-07 0.67
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 1.806e-06 0.33
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 1.921e-06 0.33
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 4.472e-06 0.65
STRP_STRP1 ska Streptokinase A 5.623e-06 0.60
BRPF1_HUMAN BRPF1 Peregrin 8.684e-06 0.33

Desipramine

SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 7.819e-26 1.00
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 7.773e-24 1.00
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 6.843e-21 1.00
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 3.749e-20 1.00
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 5.634e-18 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 3.331e-16 1.00
HRH1_RAT Hrh1 Histamine H1 receptor 1.03e-11 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.046e-09 1.00
Q63380_RAT NET Transporter 5.929e-09 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 2.797e-06 1.00
HRH2_CAVPO HRH2 Histamine H2 receptor 4.659e-06 1.00
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 5.715e-06 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.229e-05 1.00
Q9WTR4_RAT Slc6a2 Transporter 0.004075 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.005403 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.01251 1.00
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 0.01427 1.00
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 0.02016 1.00
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 0.02632 1.00
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 1.434e-68 0.34
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 5.217e-65 0.37
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 4.942e-54 0.37
PRIO_MOUSE Prnp Major prion protein 3.56e-37 0.29
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 1.326e-34 0.31
LYSC1_RAT Lyz1 Lysozyme C-1 1.567e-26 0.33
CALM_BOVIN CALM Calmodulin 2.719e-22 0.33
BGLR_RAT Gusb Beta-glucuronidase 1.541e-20 0.33
EBPL_HUMAN EBPL Emopamil-binding protein-like 1.541e-20 0.33
DRD5_RAT Drd5 D(1B) dopamine receptor 6.64e-19 0.29
CALM1_HUMAN CALM1 Calmodulin-1 1.11e-16 0.33
ACM2_PIG CHRM2 Muscarinic acetylcholine receptor M2 2.22e-16 0.31
V1AR_RAT Avpr1a Vasopressin V1a receptor 5.551e-16 0.31
ACE_HUMAN ACE Angiotensin-converting enzyme 1.776e-15 0.33
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 5.44e-15 0.49
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 7.216e-15 0.37
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 9.104e-15 0.49
PRIO_MESAU PRNP Major prion protein 2.482e-12 0.30
ERG2_YEAST ERG2 C-8 sterol isomerase 3.465e-12 0.33
DRD5_HUMAN DRD5 D(1B) dopamine receptor 7.164e-12 0.34
ACHA6_RAT Chrna6 Neuronal acetylcholine receptor subunit alpha-6 1.333e-11 0.33
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.927e-10 0.49
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2.05e-10 0.33
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 7.347e-10 0.38
TYTR_TRYCR TPR Trypanothione reductase 1.95e-09 0.49
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 2.039e-09 0.29
ANM8_HUMAN PRMT8 Protein arginine N-methyltransferase 8 5.01e-09 0.33
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.25e-08 0.49
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.604e-08 0.49
TPP2_RAT Tpp2 Tripeptidyl-peptidase 2 3.621e-08 0.30
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 8.686e-08 0.49
INMT_RABIT INMT Indolethylamine N-methyltransferase 8.849e-08 0.31
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 9.398e-08 0.34
AL3A1_HUMAN ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 1.096e-07 0.31
NEP_HUMAN MME Neprilysin 1.439e-07 0.33
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 2.217e-07 0.28
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 2.975e-07 0.31
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 3.03e-07 0.49
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 4.257e-07 0.30
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 4.997e-07 0.45
HRH1_HUMAN HRH1 Histamine H1 receptor 6.689e-07 0.49
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 6.798e-07 0.37
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 7.113e-07 0.54
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.236e-06 0.47
DRD4_RAT Drd4 D(4) dopamine receptor 2.254e-06 0.36
ACE_RABIT ACE Angiotensin-converting enzyme 2.734e-06 0.33
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 8.89e-06 0.34
HRH2_HUMAN HRH2 Histamine H2 receptor 9.151e-06 0.49

Pilocarpine

ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 7.773e-24 1.00
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 7.261e-14 1.00
ACM1_MOUSE Chrm1 Muscarinic acetylcholine receptor M1 4.142e-12 1.00
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 1.782e-11 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.6272 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.9947 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.9994 1.00
CPXA_PSEPU camC Camphor 5-monooxygenase 8.882e-16 0.30

Diphenhydramine

SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 8.714e-23 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 2.776e-14 1.00
HRH1_CAVPO HRH1 Histamine H1 receptor 3.74e-11 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 9.053e-11 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 6.485e-09 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 7.45e-09 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.993e-07 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 3.788e-07 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 8.835e-07 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 8.842e-07 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.063e-06 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 6.014e-06 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.0001981 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.006402 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.01635 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.01933 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.03291 1.00
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 1.006e-73 0.35
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 1.405e-62 0.33
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.14e-60 0.63
Q5TIX5_MYCSM atpE ATP synthase subunit c 1.291e-51 0.28
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 9.276e-47 0.59
ANM1_RAT Prmt1 Protein arginine N-methyltransferase 1 1.802e-46 0.33
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 6.994e-36 0.35
ATPL_BACP3 atpE ATP synthase subunit c 1.377e-35 0.28
CALM_BOVIN CALM Calmodulin 1.425e-21 0.31
AOC3_HUMAN AOC3 Membrane primary amine oxidase 1.238e-20 0.37
UR2R_HUMAN UTS2R Urotensin-2 receptor 1.839e-20 0.33
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 7.194e-18 0.73
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.11e-16 0.42
AMYP_RAT Amy2 Pancreatic alpha-amylase 1.776e-15 0.34
Q9WTR4_RAT Slc6a2 Transporter 2.809e-14 0.40
ERG7_PNECA ERG7 Lanosterol synthase 2.986e-13 0.29
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 4.657e-13 0.30
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 8.923e-10 0.33
Q8VH27_CAVPO GPM2 Muscarinic acetylcholine receptor 1.628e-09 0.29
ATP6_MYCTU atpB ATP synthase subunit a 4.765e-09 0.30
ATPA_MYCTU atpA ATP synthase subunit alpha 4.765e-09 0.30
ATPB_MYCTU atpD ATP synthase subunit beta 4.765e-09 0.30
ATPE_MYCTU atpC ATP synthase epsilon chain 4.765e-09 0.30
ATPFD_MYCTU atpFH ATP synthase subunit b-delta 4.765e-09 0.30
ATPF_MYCTU atpF ATP synthase subunit b 4.765e-09 0.30
ATPG_MYCTU atpG ATP synthase gamma chain 4.765e-09 0.30
ATPL_MYCTU atpE ATP synthase subunit c 4.765e-09 0.30
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 7.882e-09 0.42
CALM1_HUMAN CALM1 Calmodulin-1 8.846e-09 0.31
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 1.143e-08 0.33
HRH1_RAT Hrh1 Histamine H1 receptor 1.954e-08 0.73
HRH1_HUMAN HRH1 Histamine H1 receptor 4.046e-08 0.73
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 7.551e-08 0.44
ACHP_LYMST Acetylcholine-binding protein 7.612e-07 0.39
NORA_STAAU norA Quinolone resistance protein NorA 1.606e-06 0.31
DXR_MYCTU dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.681e-06 0.29
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.835e-06 0.34
HRH2_HUMAN HRH2 Histamine H2 receptor 2.888e-06 0.73
Q63380_RAT NET Transporter 3.271e-06 0.34
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 3.358e-06 0.50
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 4.269e-06 0.42
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 6.982e-06 0.30
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 7.812e-06 0.41

Gemifloxacin

PARC_STAAU parC DNA topoisomerase 4 subunit A 9.817e-23 1.00
GYRA_STAAU gyrA DNA gyrase subunit A 4.182e-09 1.00
GYRB_STAAU gyrB DNA gyrase subunit B 1.149e-05 1.00
Q47245_ECOLX gyrA DNA gyrase subunit A 4.557e-57 0.41
VATB2_HUMAN ATP6V1B2 V-type proton ATPase subunit B, brain isoform 3.573e-55 0.44
ACEA_MYCTU icl Isocitrate lyase 9.883e-53 0.39
C3SLN2_ECOLX gyrB DNA gyrase subunit B 2.004e-49 0.41
GLYCP_NIPAV G Glycoprotein G 5.511e-32 0.32
DPO3_BACSU polC DNA polymerase III PolC-type 3.432e-22 0.33
DPO1_THEAQ polA DNA polymerase I, thermostable 1.665e-15 0.31
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 4.323e-12 0.30
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 2.37e-09 0.33
GYRA_MYCTU gyrA DNA gyrase subunit A 9.214e-09 0.46
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 9.468e-08 0.29
MAPK3_HUMAN MAPKAPK3 MAP kinase-activated protein kinase 3 1.934e-07 0.33
GYRA_ECOLI gyrA DNA gyrase subunit A 1.172e-06 0.46
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.204e-06 0.29
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 1.806e-06 0.33
PARE_STAAU parE DNA topoisomerase 4 subunit B 5.832e-06 0.39

Diphenoxylate

KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 3.251e-19 1.00
NK2R_MOUSE Tacr2 Substance-K receptor 1.024e-62 0.33
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 5.129e-49 0.45
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 7.133e-46 0.44
S12A5_RAT Slc12a5 Solute carrier family 12 member 5 3.026e-44 0.32
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.738e-40 0.45
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 3.175e-37 0.54
DCMC_MOUSE Mlycd Malonyl-CoA decarboxylase, mitochondrial 6.2e-28 0.32
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 2.847e-23 0.29
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 2.655e-21 0.53
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.101e-20 0.38
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 4.306e-20 0.44
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.125e-17 0.38
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 2.22e-16 0.30
HRH2_HUMAN HRH2 Histamine H2 receptor 6.661e-16 0.38
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 3.109e-15 0.38
NK2R_BOVIN TACR2 Substance-K receptor 3.664e-15 0.29
ADA1B_MOUSE Adra1b Alpha-1B adrenergic receptor 7.105e-15 0.28
HRH1_HUMAN HRH1 Histamine H1 receptor 7.327e-15 0.38
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 9.437e-15 0.44
MEN1_HUMAN MEN1 Menin 2.132e-14 0.31
CALM_BOVIN CALM Calmodulin 7.816e-14 0.38
PDIA1_HUMAN P4HB Protein disulfide-isomerase 2.359e-13 0.33
NK1R_HUMAN TACR1 Substance-P receptor 3.023e-13 0.35
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 4.763e-13 0.53
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.075e-12 0.44
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 4.628e-12 0.29
NK1R_CAVPO TACR1 Substance-P receptor 6.225e-12 0.33
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.514e-11 0.42
NK2R_HUMAN TACR2 Substance-K receptor 2.161e-11 0.35
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.979e-11 0.42
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 5.442e-11 0.42
TRPC6_MOUSE Trpc6 Short transient receptor potential channel 6 8.4e-11 0.29
HRH3_RAT Hrh3 Histamine H3 receptor 9.632e-11 0.38
VACHT_TETCF Vesicular acetylcholine transporter 1.553e-10 0.34
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 1.716e-10 0.44
Q63380_RAT NET Transporter 1.992e-10 0.43
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 2.79e-10 0.30
OPRX_HUMAN OPRL1 Nociceptin receptor 4.968e-10 0.40
OPRM_HUMAN OPRM1 Mu-type opioid receptor 7.516e-10 0.61
NK2R_RAT Tacr2 Substance-K receptor 9.031e-10 0.32
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 1.012e-09 0.28
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 1.275e-09 0.41
NK1R_MERUN TACR1 Substance-P receptor 3.634e-09 0.35
OPRD_HUMAN OPRD1 Delta-type opioid receptor 5.547e-09 0.41
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 5.671e-09 0.44
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.606e-08 0.30
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 3.153e-08 0.33
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 5.519e-08 0.30
ERG2_YEAST ERG2 C-8 sterol isomerase 9.578e-08 0.29
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.072e-07 0.32
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.676e-07 0.34
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 3.436e-07 0.31
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 3.738e-07 0.31
TSHR_HUMAN TSHR Thyrotropin receptor 3.808e-07 0.30
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 6.465e-07 0.30
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 8.335e-07 0.30
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 8.443e-07 0.40
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.204e-06 0.29
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.535e-06 0.30
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 2.171e-06 0.30
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 4.057e-06 0.49
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 6.258e-06 0.32

Trimethaphan

ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 1.377e-17 1.00
A9XFY4_MUSDO nAChRalpha5 Nicotinic acetylcholine receptor alpha 5 subunit 3.375e-10 1.00
Q72874_9HIV1 pol Pol polyprotein 9.765e-43 0.44
PGH2_BOVIN PTGS2 Prostaglandin G/H synthase 2 6.877e-25 0.33
PDE5A_BOVIN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 2.805e-22 0.34
ACES_MOUSE Ache Acetylcholinesterase 1.565e-20 0.32
PDE2A_BOVIN PDE2A cGMP-dependent 3',5'-cyclic phosphodiesterase 1.705e-19 0.30
CARP2_CANAX SAP2 Candidapepsin-2 2.154e-18 0.30
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 3.642e-18 0.31
DRD2_MOUSE Drd2 D(2) dopamine receptor 1.752e-13 0.30
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 7.187e-11 0.33
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 3.732e-09 0.35
E1BN64_BOVIN PDE3B Phosphodiesterase 1.322e-08 0.29
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 2.67e-08 0.32
BACE1_MOUSE Bace1 Beta-secretase 1 5.314e-08 0.29
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 6.905e-08 0.33
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.031e-07 0.29
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.257e-07 0.36
MALT1_HUMAN MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 1.669e-07 0.29
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 4.164e-07 0.29
ITA4_HUMAN ITGA4 Integrin alpha-4 4.553e-07 0.32
FABI_BACSU fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 5.622e-07 0.28
ITB1_HUMAN ITGB1 Integrin beta-1 8.411e-07 0.32
DPP4_RAT Dpp4 Dipeptidyl peptidase 4 1.862e-06 0.32
Q9YQ12_9HIV1 protease Protease 2.174e-06 0.37
OX1R_HUMAN HCRTR1 Orexin receptor type 1 2.912e-06 0.36
OX2R_HUMAN HCRTR2 Orexin receptor type 2 3.113e-06 0.36
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 6.955e-06 0.31
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 7.341e-06 0.29

Tegaserod

5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 1.11e-16 1.00
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 4.723e-07 1.00
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 3.678e-06 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 8.513e-05 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.0002544 1.00
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 0.0002847 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.007956 1.00
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 0.05302 1.00
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 0.06322 1.00
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 7.605e-48 0.44
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.684e-42 0.44
PA2A1_NAJMO Acidic phospholipase A2 CM-I 1.023e-37 0.30
SPRE_HUMAN SPR Sepiapterin reductase 2.072e-28 0.29
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.4e-26 0.38
MTR1C_XENLA mtnr1c Melatonin receptor type 1C 7.018e-21 0.30
ASAH1_RAT Asah1 Acid ceramidase 5.226e-19 0.31
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 5.976e-18 0.33
ENV_MMTVG env Envelope glycoprotein gp70 1.11e-16 0.31
AOC1_RAT Aoc1 Amiloride-sensitive amine oxidase [copper-containing] 3.331e-16 0.43
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.665e-15 0.42
GBRA1_RAT Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 5.551e-15 0.33
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 5.773e-15 0.34
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 1.055e-14 0.33
GAG_AVIER gag Gag polyprotein 2.232e-14 0.31
GBRG2_RAT Gabrg2 Gamma-aminobutyric acid receptor subunit gamma-2 1.293e-13 0.33
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 1.888e-13 0.38
MTR1B_CHICK Melatonin receptor type 1B 2.551e-13 0.29
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 5.472e-12 0.34
CHLE_HUMAN BCHE Cholinesterase 1.793e-11 0.38
KI20A_HUMAN KIF20A Kinesin-like protein KIF20A 8.853e-11 0.32
ACES_HUMAN ACHE Acetylcholinesterase 1.056e-10 0.38
GBRA5_RAT Gabra5 Gamma-aminobutyric acid receptor subunit alpha-5 3.598e-10 0.33
GBRB3_RAT Gabrb3 Gamma-aminobutyric acid receptor subunit beta-3 4.983e-10 0.33
HDAC3_HUMAN HDAC3 Histone deacetylase 3 2.759e-09 0.42
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 4.11e-09 0.46
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 4.765e-09 0.34
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 5.763e-09 0.39
TLR4_HUMAN TLR4 Toll-like receptor 4 1.111e-08 0.37
BGLR_HUMAN GUSB Beta-glucuronidase 1.421e-08 0.33
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.67e-08 0.40
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 3.226e-08 0.32
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 7.127e-08 0.29
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 8.772e-08 0.39
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 9.553e-08 0.55
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 1.124e-07 0.36
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 2.024e-07 0.31
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 3.513e-07 0.29
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 5.694e-07 0.38
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 6.914e-07 0.32
DCAM_RAT Amd1 S-adenosylmethionine decarboxylase proenzyme 7.857e-07 0.43
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.537e-06 0.29
PAO1_MAIZE MPAO1 Polyamine oxidase 1 1.661e-06 0.35
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 1.869e-06 0.31
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 2.39e-06 0.37
T23O_MOUSE Tdo2 Tryptophan 2,3-dioxygenase 5.99e-06 0.29
SYUA_HUMAN SNCA Alpha-synuclein 8.473e-06 0.32
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 9.275e-06 0.33
HDAC2_HUMAN HDAC2 Histone deacetylase 2 9.762e-06 0.41
TLR1_MOUSE Tlr1 Toll-like receptor 1 9.817e-06 0.29
TLR2_MOUSE Tlr2 Toll-like receptor 2 9.817e-06 0.29

Levocabastine

NTR2_RAT Ntsr2 Neurotensin receptor type 2 3.331e-16 1.00
CCR2_MOUSE Ccr2 C-C chemokine receptor type 2 7.994e-66 0.34
Q6P1E0_MOUSE Syk Tyrosine-protein kinase 3.822e-30 0.33
OPRX_RAT Oprl1 Nociceptin receptor 2.595e-21 0.31
VACHT_RAT Slc18a3 Vesicular acetylcholine transporter 2.33e-19 0.34
Q8WQX9_9TRYP PDEB1 Phosphodiesterase 4.655e-18 0.37
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 6.514e-13 0.36
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 7.248e-13 0.36
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 2.472e-12 0.36
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 3.518e-12 0.36
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 4.631e-11 0.41
VACHT_TETCF Vesicular acetylcholine transporter 7.764e-11 0.35
OPRX_HUMAN OPRL1 Nociceptin receptor 9.648e-11 0.40
DRD2_MOUSE Drd2 D(2) dopamine receptor 1.195e-10 0.32
NK1R_HUMAN TACR1 Substance-P receptor 3.721e-10 0.37
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 5.289e-10 0.31
OPRM_HUMAN OPRM1 Mu-type opioid receptor 6.836e-10 0.36
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 7.06e-09 0.32
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 3.381e-08 0.33
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 3.315e-07 0.35
NK3R_HUMAN TACR3 Neuromedin-K receptor 5.013e-07 0.35
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 5.904e-07 0.28
OPRD_HUMAN OPRD1 Delta-type opioid receptor 7.17e-07 0.38
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 1.649e-06 0.35
DHI1_HUMAN HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 2.448e-06 0.39

Benzocaine

CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 1.343e-14 1.00
DCOR_MOUSE Odc1 Ornithine decarboxylase 1.69e-91 0.41
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 1.235e-67 0.36
ACRO_HUMAN ACR Acrosin 8.458e-55 0.50
PIN4_HUMAN PIN4 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 2.422e-46 0.37
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 7.618e-39 0.44
ECR_CHITE EcR Ecdysone receptor 1.947e-38 0.30
ECR_HELVI EcR Ecdysone receptor 1.947e-38 0.30
O45117_CHITE USP-1 Ultraspiracle 1.947e-38 0.30
Q6IVK1_PLOIN USP 1.947e-38 0.30
Q6RVD3_PLOIN Ecdysone receptor 1.947e-38 0.30
Q7SIF6_HELVI Gene regulation protein 1.947e-38 0.30
Q8I1M8_CHISP CsUSP Ultraspiracle 1.947e-38 0.30
Q8MYA6_CHISP CsEcR-B1 Ecdysone receptor B1 isoform 1.947e-38 0.30
Q962I5_LUCCU Ultraspiracle protein 1.947e-38 0.30
USP_CHOFU USP Protein ultraspiracle homolog 1.947e-38 0.30
MAX_HUMAN MAX Protein max 8.333e-36 0.28
HIS7_ECOLI hisB Histidine biosynthesis bifunctional protein HisB 1.038e-35 0.36
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 2.488e-33 0.44
Q4Q5W4_LEIMA Putative squalene synthase 5.014e-28 0.46
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 9.991e-27 0.44
CAC1D_HUMAN CACNA1D Voltage-dependent L-type calcium channel subunit alpha-1D 1.098e-26 0.31
CAH2_BOVIN CA2 Carbonic anhydrase 2 1.666e-26 0.38
KDM6A_HUMAN KDM6A Lysine-specific demethylase 6A 1.669e-26 0.33
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 2.424e-26 0.38
BGAL_ASPNG lacA Beta-galactosidase 9.719e-24 0.29
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 1.023e-22 0.39
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 1.313e-22 0.35
EST1_RABIT Liver carboxylesterase 1 9.926e-20 0.36
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 1.109e-19 0.33
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 1.98e-19 0.31
Q4W6C8_LEPDE LdUSP Ultraspiracle 3.691e-19 0.30
Q4W6D0_LEPDE LdEcR-A Ecdysone receptor A isoform 3.691e-19 0.30
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 5.777e-19 0.42
ERG1_RAT Sqle Squalene monooxygenase 2.375e-18 0.52
CAH14_HUMAN CA14 Carbonic anhydrase 14 3.793e-17 0.70
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 4.126e-17 0.56
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 1.11e-16 0.33
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.11e-16 0.36
PAR16_HUMAN PARP16 Protein mono-ADP-ribosyltransferase PARP16 2.22e-16 0.31
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 3.331e-16 0.49
Q31945_CHEAL Chloroplast thylakoid membrane protein (psbA) 3.331e-16 0.31
Q9GSG8_AEDAE Ultraspiracle isoform-A 5.551e-16 0.30
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.443e-15 0.42
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 3.331e-15 0.59
GATA4_MOUSE Gata4 Transcription factor GATA-4 5.884e-15 0.33
LOXL4_HUMAN LOXL4 Lysyl oxidase homolog 4 5.884e-15 0.28
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 5.884e-15 0.33
A0A0Y9T855_PLABE DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 7.105e-15 0.33
A5K1N1_PLAVS Dihydroorotate dehydrogenase, mitochondrial, putative 7.105e-15 0.33
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 8.438e-15 0.35
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 1.721e-14 0.56
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 2.753e-14 0.31
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 3.086e-14 0.42
DBF4A_HUMAN DBF4 Protein DBF4 homolog A 3.486e-14 0.37
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 7.627e-14 0.41
Q05BA5_MOUSE Ncoa3 Nuclear receptor coactivator 1.463e-13 0.33
SENP7_HUMAN SENP7 Sentrin-specific protease 7 1.841e-13 0.53
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.905e-13 0.32
KAT2A_HUMAN KAT2A Histone acetyltransferase KAT2A 3.595e-13 0.45
KMO_RAT Kmo Kynurenine 3-monooxygenase 1.17e-12 0.32
GBRA2_HUMAN GABRA2 Gamma-aminobutyric acid receptor subunit alpha-2 1.789e-12 0.38
ENPP3_HUMAN ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 2.274e-12 0.39
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 4.258e-12 0.41
SENP1_HUMAN SENP1 Sentrin-specific protease 1 4.299e-12 0.30
CAH7_HUMAN CA7 Carbonic anhydrase 7 4.411e-12 0.70
NNMT_HUMAN NNMT Nicotinamide N-methyltransferase 6.966e-12 0.29
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 9.16e-12 0.35
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 9.7e-12 0.29
TDT_HUMAN DNTT DNA nucleotidylexotransferase 9.7e-12 0.29
E3UJZ5_SPOLI Ecdysone receptor 1.688e-11 0.31
RARB_HUMAN RARB Retinoic acid receptor beta 1.842e-11 0.44
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.909e-11 0.47
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.92e-11 0.31
AA3R_HUMAN ADORA3 Adenosine receptor A3 2.424e-11 0.37
RBBP9_HUMAN RBBP9 Serine hydrolase RBBP9 2.943e-11 0.30
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 3.761e-11 0.46
GBRG2_HUMAN GABRG2 Gamma-aminobutyric acid receptor subunit gamma-2 4.003e-11 0.38
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 4.786e-11 0.42
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 9.491e-11 0.40
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 1.004e-10 0.43
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 1.068e-10 0.31
RS27_HUMAN RPS27 40S ribosomal protein S27 1.369e-10 0.28
STS_HUMAN STS Steryl-sulfatase 1.898e-10 0.39
H9B8T9_CAPHI CTSB Cathepsin B 1.999e-10 0.34
RARA_HUMAN RARA Retinoic acid receptor alpha 2.17e-10 0.44
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.53e-10 0.33
ELNE_HUMAN ELANE Neutrophil elastase 3.968e-10 0.39
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 4.057e-10 0.31
EST2_HUMAN CES2 Cocaine esterase 5.276e-10 0.36
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 5.42e-10 0.31
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 5.618e-10 0.35
RXRG_MOUSE Rxrg Retinoic acid receptor RXR-gamma 7.019e-10 0.38
TLR4_HUMAN TLR4 Toll-like receptor 4 7.789e-10 0.31
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 8.044e-10 0.32
CAH12_HUMAN CA12 Carbonic anhydrase 12 9.76e-10 0.70
ECR_LUCCU EcR Ecdysone receptor 1.021e-09 0.30
RXRB_MOUSE Rxrb Retinoic acid receptor RXR-beta 1.106e-09 0.38
DHPS_ECOLI folP Dihydropteroate synthase 1.273e-09 0.38
Q6UCJ9_TOXGO ENR Enoyl-acyl carrier reductase 1.415e-09 0.31
GSTM2_HUMAN GSTM2 Glutathione S-transferase Mu 2 1.603e-09 0.39
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 1.76e-09 0.30
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 2.37e-09 0.33
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 3.158e-09 0.42
CAH1_HUMAN CA1 Carbonic anhydrase 1 3.66e-09 0.70
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 4.438e-09 0.28
KPCZ_HUMAN PRKCZ Protein kinase C zeta type 5.97e-09 0.50
TRY1_HUMAN PRSS1 Trypsin-1 7.712e-09 0.50
PHOP1_HUMAN PHOSPHO1 Phosphoethanolamine/phosphocholine phosphatase 8.426e-09 0.45
DNAB_MYCTU dnaB Replicative DNA helicase 9.731e-09 0.42
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 1.369e-08 0.39
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 1.403e-08 0.46
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 1.428e-08 0.30
Q8IL32_PLAF7 Heat shock protein 90, putative 1.757e-08 0.56
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.892e-08 0.70
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.959e-08 0.45
RECA_MYCTU recA Protein RecA 2.326e-08 0.43
LUCI_PHOPY Luciferin 4-monooxygenase 2.571e-08 0.37
CAH9_HUMAN CA9 Carbonic anhydrase 9 2.666e-08 0.70
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 3.649e-08 0.33
ACES_HUMAN ACHE Acetylcholinesterase 3.997e-08 0.42
DDIT3_MOUSE Ddit3 DNA damage-inducible transcript 3 protein 4.221e-08 0.35
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 4.531e-08 0.36
NR4A1_HUMAN NR4A1 Nuclear receptor subfamily 4 group A member 1 5.3e-08 0.35
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6.524e-08 0.45
MGLL_RAT Mgll Monoglyceride lipase 7.272e-08 0.35
CAH13_MOUSE Ca13 Carbonic anhydrase 13 7.631e-08 0.36
CAH15_MOUSE Ca15 Carbonic anhydrase 15 1.031e-07 0.36
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.129e-07 0.34
STRP_STRP1 ska Streptokinase A 1.25e-07 0.44
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 1.494e-07 0.37
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 1.532e-07 0.42
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.558e-07 0.32
XBP1_HUMAN XBP1 X-box-binding protein 1 1.6e-07 0.33
VGFR1_MOUSE Flt1 Vascular endothelial growth factor receptor 1 2.193e-07 0.29
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 2.869e-07 0.28
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 3.1e-07 0.42
PLMN_RAT Plg Plasminogen 3.351e-07 0.30
ACRO_PIG ACR Acrosin 3.537e-07 0.35
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 4.172e-07 0.56
TRPA1_MOUSE Trpa1 Transient receptor potential cation channel subfamily A member 1 4.268e-07 0.29
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 4.38e-07 0.35
CLAT_RAT Chat Choline O-acetyltransferase 4.905e-07 0.29
HKDC1_HUMAN HKDC1 Hexokinase HKDC1 5.1e-07 0.35
ODP2_MYCTU dlaT Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex 5.174e-07 0.29
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 6.027e-07 0.31
BGAL_HUMAN GLB1 Beta-galactosidase 7.045e-07 0.29
O77240_CHOFU EcR Ecdysone receptor isoform A 7.091e-07 0.30
TLR4_MOUSE Tlr4 Toll-like receptor 4 7.619e-07 0.32
TLR1_MOUSE Tlr1 Toll-like receptor 1 8.801e-07 0.35
TLR2_MOUSE Tlr2 Toll-like receptor 2 8.801e-07 0.35
5NTD_HUMAN NT5E 5'-nucleotidase 9.433e-07 0.32
GYRB_MYCSM gyrB DNA gyrase subunit B 1.27e-06 0.31
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.294e-06 0.33
GBRB_MUSDO Rdl Gamma-aminobutyric acid receptor subunit beta 1.334e-06 0.33
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.346e-06 0.29
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.367e-06 0.41
CP19A_HUMAN CYP19A1 Aromatase 1.467e-06 0.45
MITF_HUMAN MITF Microphthalmia-associated transcription factor 1.618e-06 0.43
DYR_PNECA Dihydrofolate reductase 1.635e-06 0.38
EST1_HUMAN CES1 Liver carboxylesterase 1 1.799e-06 0.36
GBRA4_HUMAN GABRA4 Gamma-aminobutyric acid receptor subunit alpha-4 1.849e-06 0.31
DHI1_RAT Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 1.977e-06 0.29
GBRA6_HUMAN GABRA6 Gamma-aminobutyric acid receptor subunit alpha-6 2.001e-06 0.33
CAH6_HUMAN CA6 Carbonic anhydrase 6 2.099e-06 0.36
LDLR_HUMAN LDLR Low-density lipoprotein receptor 2.26e-06 0.29
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 2.392e-06 0.43
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 2.849e-06 0.29
PRTN3_HUMAN PRTN3 Myeloblastin 3.161e-06 0.35
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 4.025e-06 0.46
FA10_BOVIN F10 Coagulation factor X 4.282e-06 0.29
ECR_BOMMO EcR Ecdysone receptor 5.117e-06 0.31
CAH_METTE Carbonic anhydrase 5.875e-06 0.29
LUCI_AQULA Luciferin 4-monooxygenase 6.235e-06 0.29
Q91H74_9FLAV Genome polyprotein 6.965e-06 0.32
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 7.229e-06 0.39
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 7.69e-06 0.29
LYOX_HUMAN LOX Protein-lysine 6-oxidase 7.85e-06 0.28
GSTP1_HUMAN GSTP1 Glutathione S-transferase P 7.864e-06 0.39
CDC7_HUMAN CDC7 Cell division cycle 7-related protein kinase 8.196e-06 0.37
FOLC_HUMAN FPGS Folylpolyglutamate synthase, mitochondrial 9.511e-06 0.29
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 9.702e-06 0.33

Sibutramine

SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 1.079e-13 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 5.601e-12 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 7.576e-09 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.01743 1.00
DHI1_MOUSE Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 1.399e-14 0.32
CHKA_HUMAN CHKA Choline kinase alpha 1.794e-07 0.30
DHI1_HUMAN HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 9.908e-07 0.35
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 3.03e-06 0.29

Iloprost

PI2R_HUMAN PTGIR Prostacyclin receptor 2.531e-13 1.00
PI2R_RAT Ptgir Prostacyclin receptor 1.337e-10 1.00
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 0.01054 1.00
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 7.498e-54 0.35
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 1.397e-51 0.35
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 7.381e-50 0.35
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 2.707e-42 0.35
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 9.324e-40 0.35
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 6.782e-33 0.35
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 1.199e-22 0.35
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 1.285e-21 0.35
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 6.721e-21 0.46
PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 3.075e-19 0.35
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 2.22e-16 0.35
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 3.463e-12 0.35
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 6.598e-12 0.35
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 5.38e-09 0.44
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 7.713e-08 0.35
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 3.352e-07 0.35

Promethazine

ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 4.846e-13 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 3.137e-12 1.00
PRIO_HUMAN PRNP Major prion protein 2.339e-10 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 3.455e-10 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 2.748e-08 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 5.288e-07 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.162e-06 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.228e-06 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 2.493e-06 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 6.366e-06 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 7.201e-06 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.199e-05 1.00
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 5.149e-05 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 9.404e-05 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.000286 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.0008228 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.0008278 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.001881 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.002498 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.003145 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.0114 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.01811 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.03528 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.04376 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.05157 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 0.235 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 0.3245 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.3304 1.00
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 1.082e-117 0.51
PRIO_MOUSE Prnp Major prion protein 1.573e-54 0.43
TYTR_TRYCR TPR Trypanothione reductase 1.328e-35 0.43
CALM_BOVIN CALM Calmodulin 3.712e-27 0.43
LYSC1_RAT Lyz1 Lysozyme C-1 1.567e-26 0.33
CHLE_HUMAN BCHE Cholinesterase 3.655e-26 0.74
ITAM_HUMAN ITGAM Integrin alpha-M 4.502e-26 0.32
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 2.689e-22 0.43
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 1.83e-21 0.33
BGLR_RAT Gusb Beta-glucuronidase 1.541e-20 0.33
EBPL_HUMAN EBPL Emopamil-binding protein-like 1.541e-20 0.33
CALM1_HUMAN CALM1 Calmodulin-1 2.189e-20 0.43
NOX1_HUMAN NOX1 NADPH oxidase 1 6.414e-20 0.39
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 1.183e-13 0.38
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 8.628e-12 0.38
DEF_STAAM def Peptide deformylase 5.278e-11 0.30
DDAH1_HUMAN DDAH1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 2.8e-08 0.29
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 4.702e-08 0.43
CAC1S_HUMAN CACNA1S Voltage-dependent L-type calcium channel subunit alpha-1S 1.161e-07 0.31
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 4.404e-07 0.33
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.702e-06 0.43
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 4.877e-06 0.31

Butenafine

ACES_HUMAN ACHE Acetylcholinesterase 1.357e-09 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.008e-06 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.000169 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.005645 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.04808 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.0516 1.00
INAR1_HUMAN IFNAR1 Interferon alpha/beta receptor 1 4.048e-41 0.33
DRD2_CHLAE DRD2 D(2) dopamine receptor 1.864e-39 0.33
CRTN_STAA3 crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 3.409e-38 0.33
CRTN_STAAW crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 8.872e-32 0.33
CRTN_STAAE crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 2.61e-31 0.48
ANM1_RAT Prmt1 Protein arginine N-methyltransferase 1 2.272e-28 0.43
CRTN_STAAM crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 1.824e-20 0.33
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 1.284e-19 0.37
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 2.663e-19 0.40
ERG1_HUMAN SQLE Squalene monooxygenase 2.22e-16 0.49
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 6.661e-16 0.33
FTSZ_ECOLI ftsZ Cell division protein FtsZ 1.665e-15 0.29
FTSZ_STAAU ftsZ Cell division protein FtsZ 1.665e-15 0.29
CHIT1_HUMAN CHIT1 Chitotriosidase-1 1.119e-11 0.30
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 7.457e-11 0.30
CHIA_MOUSE Chia Acidic mammalian chitinase 1.291e-10 0.30
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 1.807e-09 0.38
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 1.878e-08 0.40
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 3.288e-08 0.31
CHIT1_MOUSE Chit1 Chitotriosidase-1 1.197e-07 0.30
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 3.89e-07 0.40
EST1_PIG Liver carboxylesterase 7.646e-07 0.33
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 1.63e-06 0.31
CHIA_HUMAN CHIA Acidic mammalian chitinase 9.348e-06 0.30

Sertaconazole

I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 9.072e-09 1.00
Q8IL32_PLAF7 Heat shock protein 90, putative 1.83e-05 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 6.37e-05 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.004007 1.00
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 0.00572 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.009472 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.03566 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.04011 1.00
CP121_MYCTU cyp121 Mycocyclosin synthase 4.769e-50 0.63
CP74A_ARATH CYP74A Allene oxide synthase, chloroplastic 5.719e-41 0.49
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 4.241e-32 0.63
A2TEF2_LEIIN CYP51 Putative lanosterol 14-alpha-demethylase 1.476e-29 0.37
THAS_RAT Tbxas1 Thromboxane-A synthase 8.704e-29 0.36
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 8.475e-25 0.63
CP51_CANAL ERG11 Lanosterol 14-alpha demethylase 7.35e-23 0.37
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 3.447e-19 0.63
HMOX1_RAT Hmox1 Heme oxygenase 1 7.216e-15 0.33
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 8.304e-14 0.63
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 4.812e-13 0.42
HMOX2_RAT Hmox2 Heme oxygenase 2 5.866e-13 0.33
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 5.063e-12 0.63
TRPC6_MOUSE Trpc6 Short transient receptor potential channel 6 4.393e-11 0.30
Q690N0_BOVIN PGR Progesterone receptor 1.021e-07 0.63
CP19A_HUMAN CYP19A1 Aromatase 3.983e-07 0.47
THAS_HUMAN TBXAS1 Thromboxane-A synthase 7.768e-07 0.63
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 4.58e-06 0.72

Anisindione

LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.033e-08 1.00
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 1.146e-80 0.37
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 2.837e-77 0.35
CP27A_HUMAN CYP27A1 Sterol 26-hydroxylase, mitochondrial 4.697e-56 0.34
EAA1_RAT Slc1a3 Excitatory amino acid transporter 1 2.44e-41 0.33
Q17SB2_PLAFA Plasmepsin 4 2.018e-36 0.32
CAC1S_HUMAN CACNA1S Voltage-dependent L-type calcium channel subunit alpha-1S 3.184e-32 0.33
PLM2_PLAFA Plasmepsin-2 1.127e-28 0.35
NPBW1_HUMAN NPBWR1 Neuropeptides B/W receptor type 1 1.607e-25 0.36
TPPP_BOVIN TPPP Tubulin polymerization-promoting protein 5.379e-25 0.31
CP24A_RAT Cyp24a1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1.354e-24 0.33
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 2.752e-23 0.30
CP1A1_RAT Cyp1a1 Cytochrome P450 1A1 1.421e-22 0.31
PDE5A_BOVIN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 3.332e-21 0.33
1A15_ARATH ACS5 1-aminocyclopropane-1-carboxylate synthase 5 5.223e-20 0.38
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 1.55e-19 0.47
KAT3_HUMAN KYAT3 Kynurenine--oxoglutarate transaminase 3 3.691e-19 0.30
PPARG_RAT Pparg Peroxisome proliferator-activated receptor gamma 5.026e-19 0.32
P2RX7_MOUSE P2rx7 P2X purinoceptor 7 5.084e-19 0.53
AHR_RABIT AHR Aryl hydrocarbon receptor 6.477e-19 0.31
PERL_BOVIN LPO Lactoperoxidase 7.28e-19 0.32
CEL2A_RAT Cela2a Chymotrypsin-like elastase family member 2A 1.265e-18 0.30
DUS1_MOUSE Dusp1 Dual specificity protein phosphatase 1 2.576e-18 0.29
KLK14_HUMAN KLK14 Kallikrein-14 7.502e-18 0.28
TOP2_PLAFK TOP2 DNA topoisomerase 2 7.502e-18 0.28
Q56950_YERPE ybtE Salicyl-AMP ligase YbtE 4.049e-17 0.32
H9B8T9_CAPHI CTSB Cathepsin B 7.772e-16 0.35
T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 8.882e-16 0.30
LUCI_PHOPE Luciferin 4-monooxygenase 1.332e-15 0.33
LUCI_PHOPY Luciferin 4-monooxygenase 1.443e-15 0.53
PPAP_HUMAN ACP3 Prostatic acid phosphatase 2.998e-15 0.30
A0A060INS8_CAPHI CTSH Cathepsin H 3.109e-15 0.36
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 3.22e-15 0.31
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 8.105e-15 0.49
TF65_HUMAN RELA Transcription factor p65 9.881e-15 0.32
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 1.055e-14 0.36
CBS_HUMAN CBS Cystathionine beta-synthase 1.66e-13 0.37
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 2.387e-13 0.38
Q93EK7_NEIME lgtC LgtC 2.986e-13 0.29
FIBB_HUMAN FGB Fibrinogen beta chain 6.608e-13 0.35
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 1.099e-12 0.32
CAH13_MOUSE Ca13 Carbonic anhydrase 13 1.145e-12 0.41
Q38C41_TRYB2 Phosphotransferase 1.631e-12 0.37
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.786e-12 0.38
CAH15_MOUSE Ca15 Carbonic anhydrase 15 1.88e-12 0.41
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 2.299e-12 0.32
SENP7_HUMAN SENP7 Sentrin-specific protease 7 5.961e-12 0.51
BAZ2A_HUMAN BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 6.28e-12 0.29
SENP6_HUMAN SENP6 Sentrin-specific protease 6 6.913e-12 0.51
EST1_RABIT Liver carboxylesterase 1 9.38e-12 0.41
PRTN3_HUMAN PRTN3 Myeloblastin 2.758e-11 0.35
EST2_HUMAN CES2 Cocaine esterase 2.94e-11 0.44
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 4.228e-11 0.31
BAZ2B_HUMAN BAZ2B Bromodomain adjacent to zinc finger domain protein 2B 7.253e-11 0.29
RBBP9_HUMAN RBBP9 Serine hydrolase RBBP9 1.415e-10 0.28
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 2.052e-10 0.37
IL2_HUMAN IL2 Interleukin-2 2.557e-10 0.29
G3P_HUMAN GAPDH Glyceraldehyde-3-phosphate dehydrogenase 3.074e-10 0.38
MOT4_HUMAN SLC16A3 Monocarboxylate transporter 4 6.468e-10 0.31
KCNA1_HUMAN KCNA1 Potassium voltage-gated channel subfamily A member 1 1.206e-09 0.30
EST1_HUMAN CES1 Liver carboxylesterase 1 1.229e-09 0.44
C1R_HUMAN C1R Complement C1r subcomponent 1.905e-09 0.35
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 1.972e-09 0.40
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 2.546e-09 0.57
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 2.765e-09 0.53
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 3.157e-09 0.33
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 4.69e-09 0.34
SCAF_HHV11 UL26 Capsid scaffolding protein 4.69e-09 0.34
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 4.74e-09 0.34
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 5.769e-09 0.33
STXA_SHIDY stxA Shiga toxin subunit A 5.818e-09 0.32
MAP1_ECOLI map Methionine aminopeptidase 6.12e-09 0.33
CAH14_HUMAN CA14 Carbonic anhydrase 14 8.814e-09 0.42
IMDH_CRYNJ Inosine-5'-monophosphate dehydrogenase 9.523e-09 0.29
E1BN64_BOVIN PDE3B Phosphodiesterase 9.882e-09 0.29
RECA_MYCTU recA Protein RecA 1.152e-08 0.43
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 1.321e-08 0.30
CAH1_HORSE CA1 Carbonic anhydrase 1 1.322e-08 0.29
BGLR_HUMAN GUSB Beta-glucuronidase 1.662e-08 0.34
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 1.906e-08 0.37
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 2.093e-08 0.37
AOC3_HUMAN AOC3 Membrane primary amine oxidase 2.171e-08 0.31
Q49PX0_9POXV N1L N1L 2.237e-08 0.30
CATE_HUMAN CTSE Cathepsin E 2.278e-08 0.32
KLK7_HUMAN KLK7 Kallikrein-7 2.528e-08 0.30
GRM7_RAT Grm7 Metabotropic glutamate receptor 7 2.952e-08 0.30
AOC3_BOVIN AOC3 Membrane primary amine oxidase 4.633e-08 0.30
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 5.445e-08 0.31
CAH3_HUMAN CA3 Carbonic anhydrase 3 6.689e-08 0.34
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 8.922e-08 0.34
A4_HUMAN APP Amyloid-beta precursor protein 9.903e-08 0.36
LEP_ECOLI lepB Signal peptidase I 1e-07 0.30
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.002e-07 0.32
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.031e-07 0.29
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1.106e-07 0.30
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.143e-07 0.42
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.191e-07 0.38
A3KMY8_BOVIN GUSB Beta-glucuronidase 1.258e-07 0.34
Q9BEG3_BOVIN 5-lipoxygenase 1.568e-07 0.33
G6PC_HUMAN G6PC Glucose-6-phosphatase 1.995e-07 0.29
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 2.075e-07 0.34
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 2.141e-07 0.29
NR4A2_HUMAN NR4A2 Nuclear receptor subfamily 4 group A member 2 2.163e-07 0.30
WDR48_HUMAN WDR48 WD repeat-containing protein 48 2.498e-07 0.31
STE24_YEAST STE24 CAAX prenyl protease 1 2.641e-07 0.29
ACES_ELEEL ache Acetylcholinesterase 3.183e-07 0.36
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 3.345e-07 0.31
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 3.973e-07 0.31
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 4.607e-07 0.41
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 4.698e-07 0.29
CAH3_BOVIN CA3 Carbonic anhydrase 3 4.707e-07 0.30
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 5.556e-07 0.33
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 6.578e-07 0.32
DNAB_MYCTU dnaB Replicative DNA helicase 8.236e-07 0.41
OXDA_MOUSE Dao D-amino-acid oxidase 8.292e-07 0.33
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 8.549e-07 0.38
Q3Y5H1_9GAMC 3C-like protease 8.598e-07 0.30
TLR4_MOUSE Tlr4 Toll-like receptor 4 8.83e-07 0.31
TAU_HUMAN MAPT Microtubule-associated protein tau 9.663e-07 0.36
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.127e-06 0.37
AOFB_RAT Maob Amine oxidase [flavin-containing] B 1.149e-06 0.40
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 1.72e-06 0.41
AMPN_PIG ANPEP Aminopeptidase N 1.962e-06 0.38
CAH7_HUMAN CA7 Carbonic anhydrase 7 2.311e-06 0.42
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 2.754e-06 0.38
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 2.945e-06 0.34
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 3.013e-06 0.37
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 3.047e-06 0.29
KLK5_HUMAN KLK5 Kallikrein-5 3.272e-06 0.28
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 3.276e-06 0.37
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 3.469e-06 0.30
5NTD_HUMAN NT5E 5'-nucleotidase 3.677e-06 0.29
BLA2_BACCE blm Metallo-beta-lactamase type 2 3.933e-06 0.30
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 4.261e-06 0.31
CAH2_HUMAN CA2 Carbonic anhydrase 2 5.213e-06 0.42
CP19A_HUMAN CYP19A1 Aromatase 5.239e-06 0.42
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 5.416e-06 0.35
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 6.099e-06 0.61
HKDC1_HUMAN HKDC1 Hexokinase HKDC1 6.55e-06 0.39
LUCI_AQULA Luciferin 4-monooxygenase 7.112e-06 0.29
P2RX2_RAT P2rx2 P2X purinoceptor 2 7.41e-06 0.35
TTHY_HUMAN TTR Transthyretin 8.32e-06 0.40
CAH1_HUMAN CA1 Carbonic anhydrase 1 8.722e-06 0.42
SYUA_HUMAN SNCA Alpha-synuclein 8.982e-06 0.36
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 9.511e-06 0.29
RPGF4_HUMAN RAPGEF4 Rap guanine nucleotide exchange factor 4 9.957e-06 0.29

Cefuroxime

CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 6.728e-08 1.00
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 6.151e-94 0.59
B2ZTR6_ACIBA Beta-lactamase 2.177e-62 0.59
D6NSM8_ACIBA ampC Beta-lactamase 2.177e-62 0.59
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 6.875e-58 0.59
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.13e-51 0.59
Q7DHH4_STAAU mecA MecA 1.731e-38 0.30
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 2.961e-31 0.39
ADA2A_PIG ADRA2A Alpha-2A adrenergic receptor 6.794e-23 0.28
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 9.444e-23 0.41
A2RP81_CITFR blaPER-2 Beta-lactamase 1.406e-19 0.44
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 7.65e-18 0.34
CASB_RAT Csn2 Beta-casein 6.325e-13 0.28
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 2.582e-11 0.38
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.342e-10 0.49
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 3.017e-10 0.41
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 4.284e-08 0.29
STRP_STRP1 ska Streptokinase A 7.802e-08 0.49

Miconazole

Q8IL32_PLAF7 Heat shock protein 90, putative 1.53e-06 1.00
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 0.001319 1.00
DNAB_MYCTU dnaB Replicative DNA helicase 0.002896 1.00
RECA_MYCTU recA Protein RecA 0.1151 1.00
CP121_MYCTU cyp121 Mycocyclosin synthase 1.32e-62 0.79
A2TEF2_LEIIN CYP51 Putative lanosterol 14-alpha-demethylase 9.875e-56 0.41
CP11A_RAT Cyp11a1 Cholesterol side-chain cleavage enzyme, mitochondrial 8.164e-52 0.28
CP7A1_RAT Cyp7a1 Cytochrome P450 7A1 8.164e-52 0.28
CP74A_ARATH CYP74A Allene oxide synthase, chloroplastic 1.479e-48 0.58
THAS_RAT Tbxas1 Thromboxane-A synthase 1.043e-43 0.38
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 4.413e-40 0.79
HMOX1_RAT Hmox1 Heme oxygenase 1 3.227e-36 0.40
CP3A5_HUMAN CYP3A5 Cytochrome P450 3A5 1.007e-35 0.28
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 6.364e-31 0.79
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1.037e-29 0.41
CP21A_HUMAN CYP21A2 Steroid 21-hydroxylase 3.962e-29 0.28
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 1.084e-25 0.79
CP51A_RAT Cyp51a1 Lanosterol 14-alpha demethylase 1.211e-25 0.28
CP51_CANAL ERG11 Lanosterol 14-alpha demethylase 2.01e-25 0.41
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 6.9e-24 0.79
HMOX2_RAT Hmox2 Heme oxygenase 2 4.003e-22 0.40
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 1.5e-18 0.28
THAS_HUMAN TBXAS1 Thromboxane-A synthase 3.054e-17 0.79
CPXA_PSEPU camC Camphor 5-monooxygenase 4.11e-17 0.33
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.11e-16 0.40
LUXR_ALIFS luxR Transcriptional activator protein LuxR 1.11e-16 0.58
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 2.22e-16 0.79
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 4.441e-16 0.40
TRPC6_MOUSE Trpc6 Short transient receptor potential channel 6 4.495e-13 0.35
CP19A_HUMAN CYP19A1 Aromatase 1.078e-12 0.55
SHIP2_HUMAN INPPL1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 1.383e-11 0.28
I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 5.056e-11 0.79
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 9.708e-11 0.40
Q690N0_BOVIN PGR Progesterone receptor 1.612e-09 0.79
CP19A_RAT Cyp19a1 Aromatase 1.177e-08 0.31
CP26A_HUMAN CYP26A1 Cytochrome P450 26A1 1.498e-08 0.31
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 7.769e-08 0.79
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1.784e-06 0.41
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 2.027e-06 0.41
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 2.049e-06 0.29
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 2.523e-06 0.79
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 5.31e-06 0.28
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 7.112e-06 0.29
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 7.543e-06 0.34

Acetophenazine

ANDR_RAT Ar Androgen receptor 4.41e-05 1.00
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 5.807e-143 0.71
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 1.247e-74 0.43
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.852e-71 0.65
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 2.051e-69 0.33
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 7.6e-60 0.32
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 1.355e-57 0.30
PRIO_MOUSE Prnp Major prion protein 4.562e-54 0.43
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.557e-52 0.65
DRD1_PIG DRD1 D(1A) dopamine receptor 1.856e-52 0.34
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.335e-51 0.71
TYTR_TRYCR TPR Trypanothione reductase 2.916e-47 0.43
DRD5_RAT Drd5 D(1B) dopamine receptor 8.21e-47 0.29
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.057e-44 0.43
LYSC1_RAT Lyz1 Lysozyme C-1 3.904e-44 0.55
DRD4_HUMAN DRD4 D(4) dopamine receptor 4.124e-44 0.65
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 1.362e-43 0.65
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 2.289e-43 0.39
DRD2_RAT Drd2 D(2) dopamine receptor 4.374e-39 0.55
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 1.827e-37 0.29
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 2.46e-37 0.71
CALM_BOVIN CALM Calmodulin 8.647e-35 0.55
BGLR_RAT Gusb Beta-glucuronidase 4.812e-34 0.55
EBPL_HUMAN EBPL Emopamil-binding protein-like 4.812e-34 0.55
DRD3_RAT Drd3 D(3) dopamine receptor 1.347e-33 0.34
NOX1_HUMAN NOX1 NADPH oxidase 1 8.273e-31 0.56
CHLE_HUMAN BCHE Cholinesterase 6.789e-28 0.41
HRH1_HUMAN HRH1 Histamine H1 receptor 6.85e-28 0.65
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 1.463e-26 0.29
CALM1_HUMAN CALM1 Calmodulin-1 4.57e-26 0.55
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.978e-24 0.65
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.239e-20 0.65
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.425e-20 0.40
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 3.868e-20 0.65
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 6.698e-20 0.36
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 1.692e-19 0.30
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.396e-18 0.65
DRD4_RAT Drd4 D(4) dopamine receptor 1.986e-18 0.32
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 3.715e-18 0.65
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.18e-17 0.36
DRD5_HUMAN DRD5 D(1B) dopamine receptor 1.11e-16 0.65
ERG2_YEAST ERG2 C-8 sterol isomerase 1.11e-16 0.55
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 2.22e-16 0.36
Q25856_PLAFA PFG6PD Glucose-6-phosphate dehydrogenase 2.22e-16 0.33
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.331e-16 0.65
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 7.772e-16 0.65
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 7.772e-16 0.59
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 8.882e-16 0.30
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 5.44e-15 0.32
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.243e-14 0.65
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2.642e-14 0.55
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 3.186e-14 0.78
AAKG1_HUMAN PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 4.197e-14 0.30
DRD1_RAT Drd1 D(1A) dopamine receptor 6.184e-14 0.43
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 1.751e-13 0.37
HRH2_HUMAN HRH2 Histamine H2 receptor 2.214e-13 0.65
AAPK2_HUMAN PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 3.372e-13 0.30
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 1.385e-12 0.30
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 1.983e-12 0.65
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 2.393e-12 0.31
5HT3B_MOUSE Htr3b 5-hydroxytryptamine receptor 3B 2.443e-12 0.30
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 6.876e-12 0.65
CHLE_HORSE BCHE Cholinesterase 7.721e-12 0.51
DRD2_BOVIN DRD2 D(2) dopamine receptor 8.775e-12 0.43
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 1.059e-11 0.32
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 1.444e-11 0.29
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 2.633e-11 0.36
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 4.884e-11 0.30
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 6.574e-11 0.31
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 1.657e-10 0.32
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 2.303e-10 0.37
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 2.367e-10 0.31
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 6.439e-10 0.29
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 1.254e-09 0.31
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.284e-09 0.65
HRH1_RAT Hrh1 Histamine H1 receptor 1.09e-08 0.42
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.126e-08 0.65
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 1.17e-08 0.39
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.352e-08 0.65
PRIO_HUMAN PRNP Major prion protein 2.656e-08 0.66
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 2.866e-08 0.65
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 5.438e-08 0.43
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 6.905e-08 0.65
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 9.041e-08 0.65
DEF_STAAM def Peptide deformylase 9.226e-08 0.31
ACES_ELEEL ache Acetylcholinesterase 9.842e-08 0.36
WDR48_HUMAN WDR48 WD repeat-containing protein 48 1.088e-07 0.55
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 1.479e-07 0.55
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.689e-07 0.65
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 1.995e-07 0.29
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 5.984e-07 0.65
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 6.994e-07 0.30
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 1.281e-06 0.38
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 1.846e-06 0.50
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.846e-06 0.33
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.91e-06 0.43
ACES_HUMAN ACHE Acetylcholinesterase 3.135e-06 0.40
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 3.143e-06 0.32
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 3.823e-06 0.44
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 4.352e-06 0.37
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 7.946e-06 0.32
HRH1_CAVPO HRH1 Histamine H1 receptor 9.131e-06 0.43
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 9.673e-06 0.32

Flavoxate

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.0001204 1.00
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 6.243e-90 0.36
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 1.286e-45 0.42
NORA_STAAU norA Quinolone resistance protein NorA 3.175e-44 0.33
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 5.286e-40 0.43
I6X8D2_MYCTU pks13 Polyketide synthase Pks13 6.244e-40 0.32
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 4.64e-32 0.32
GRP1_HUMAN RASGRP1 RAS guanyl-releasing protein 1 4.623e-31 0.31
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 1.139e-27 0.32
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 1.834e-27 0.48
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 2.859e-26 0.32
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 9.97e-25 0.33
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.676e-22 0.31
CHLE_HORSE BCHE Cholinesterase 1.707e-21 0.46
Q6Q253_PIG 5-HT4R 5-hydroxytryptamine receptor 4 protein 5.165e-21 0.30
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.929e-20 0.36
ACES_ELEEL ache Acetylcholinesterase 6.411e-20 0.46
GPC6A_MOUSE Gprc6a G-protein coupled receptor family C group 6 member A 7.563e-20 0.32
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.06e-19 0.35
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 1.072e-18 0.33
HRH3_HUMAN HRH3 Histamine H3 receptor 2.667e-18 0.37
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 4.572e-17 0.38
HRH1_CAVPO HRH1 Histamine H1 receptor 1.11e-16 0.32
ESR1_HUMAN ESR1 Estrogen receptor 9.992e-16 0.40
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 2.109e-15 0.35
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.109e-15 0.44
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 2.156e-13 0.33
HRH2_HUMAN HRH2 Histamine H2 receptor 4.406e-13 0.35
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.789e-12 0.30
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 4.114e-12 0.30
ADCY5_RAT Adcy5 Adenylate cyclase type 5 5.603e-12 0.32
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 1.15e-11 0.28
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 1.193e-11 0.34
HNMT_RAT Hnmt Histamine N-methyltransferase 1.266e-11 0.30
ESR2_HUMAN ESR2 Estrogen receptor beta 2.712e-11 0.40
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 3.204e-11 0.32
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 3.44e-11 0.34
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 5.752e-11 0.56
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.165e-10 0.35
ESR1_RAT Esr1 Estrogen receptor 5.552e-10 0.34
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 7.936e-10 0.35
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 8.665e-10 0.38
KCNJ3_RAT Kcnj3 G protein-activated inward rectifier potassium channel 1 1.063e-09 0.30
KCNJ5_RAT Kcnj5 G protein-activated inward rectifier potassium channel 4 1.063e-09 0.30
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 1.184e-09 0.33
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.73e-09 0.34
V1BR_RAT Avpr1b Vasopressin V1b receptor 1.733e-09 0.31
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 1.832e-09 0.34
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.846e-09 0.35
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 3.529e-09 0.39
CLTR1_HUMAN CYSLTR1 Cysteinyl leukotriene receptor 1 4.129e-09 0.38
PTPRF_HUMAN PTPRF Receptor-type tyrosine-protein phosphatase F 4.786e-09 0.30
ACHA3_HUMAN CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 7.549e-09 0.34
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.075e-08 0.35
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.145e-08 0.56
STXA_SHIDY stxA Shiga toxin subunit A 3.985e-08 0.29
MRP2_HUMAN ABCC2 Canalicular multispecific organic anion transporter 1 4.908e-08 0.30
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.451e-07 0.37
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.874e-07 0.55
ALBU_HUMAN ALB Serum albumin 5.282e-07 0.30
DRD2_RAT Drd2 D(2) dopamine receptor 6.082e-07 0.44
TYTR_TRYBB TPR Trypanothione reductase 7.062e-07 0.30
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 9.626e-07 0.33
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.084e-06 0.35
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.918e-06 0.35
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 2.101e-06 0.33
KLK7_HUMAN KLK7 Kallikrein-7 2.522e-06 0.34
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 3.044e-06 0.29
FOS_HUMAN FOS Proto-oncogene c-Fos 3.861e-06 0.29
KPCA_MOUSE Prkca Protein kinase C alpha type 4.761e-06 0.32
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 6.048e-06 0.31
NPSR1_HUMAN NPSR1 Neuropeptide S receptor 6.484e-06 0.30
TRYP_PIG Trypsin 6.758e-06 0.32
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 7.085e-06 0.37
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 7.652e-06 0.28
AGP1_YEAST AGP1 General amino acid permease AGP1 8.833e-06 0.28

Ambenonium

ACES_BOVIN ACHE Acetylcholinesterase 0.0007667 1.00
DXS_HAEI8 dxs 1-deoxy-D-xylulose-5-phosphate synthase 9.7e-55 0.35
DXS_ARATH DXS 1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic 3.56e-37 0.29
IL8_HUMAN CXCL8 Interleukin-8 2.226e-36 0.36
ANM1_RAT Prmt1 Protein arginine N-methyltransferase 1 6.978e-36 0.32
USP_DROME usp Protein ultraspiracle 7.734e-25 0.31
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 6.191e-24 0.33
TRXR1_HUMAN TXNRD1 Thioredoxin reductase 1, cytoplasmic 1.961e-23 0.30
Q8MWR1_SPOFR USP Ultraspiracle protein 4.514e-21 0.30
Q8MWR2_SPOFR EcR Ecdysteroid receptor 4.514e-21 0.30
ECR_DROME EcR Ecdysone receptor 2.208e-20 0.31
ECR_BOMMO EcR Ecdysone receptor 6.057e-18 0.31
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 1.321e-14 0.32
A0A0Y9T855_PLABE DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 4.967e-13 0.28
A5K1N1_PLAVS Dihydroorotate dehydrogenase, mitochondrial, putative 4.967e-13 0.28
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 3.051e-12 0.38
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 3.631e-12 0.35
Q2TU57_MAIZE Sterol-8,7-isomerase 4.437e-12 0.33
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 6.032e-12 0.35
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 2.6e-11 0.35
GBRA1_RAT Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 8.016e-11 0.38
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 8.923e-11 0.34
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 1.259e-10 0.38
PE2R3_RAT Ptger3 Prostaglandin E2 receptor EP3 subtype 2.368e-10 0.30
PDS_SYNE7 pds 15-cis-phytoene desaturase 3.541e-10 0.33
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 4.069e-10 0.31
GBRG2_RAT Gabrg2 Gamma-aminobutyric acid receptor subunit gamma-2 7.577e-10 0.38
FABP5_HUMAN FABP5 Fatty acid-binding protein 5 1.098e-09 0.31
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 1.793e-09 0.30
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 5.776e-09 0.36
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.44e-08 0.39
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 2.301e-08 0.31
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 2.311e-08 0.31
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 5.753e-08 0.37
OPRK_RAT Oprk1 Kappa-type opioid receptor 9.184e-08 0.29
E3UJZ5_SPOLI Ecdysone receptor 1.683e-07 0.29
TTHY_HUMAN TTR Transthyretin 6.049e-07 0.34
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.141e-06 0.30
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 1.154e-06 0.30
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 1.248e-06 0.36
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 2.002e-06 0.35
CAN_CANAL NCE103 Carbonic anhydrase 2.157e-06 0.31
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 2.331e-06 0.35
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 5.309e-06 0.31
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 6.016e-06 0.34

Azlocillin

STRP_STRP1 ska Streptokinase A 0.001039 1.00
Q82134_9DELA prt Protease 1.223e-115 0.31
Q82323_9DELA Protease 1.849e-76 0.30
BIRC8_HUMAN BIRC8 Baculoviral IAP repeat-containing protein 8 3.143e-69 0.32
PRO_HTL1A gag-pro Gag-Pro polyprotein 8.42e-41 0.31
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 3.392e-34 0.42
A2RP81_CITFR blaPER-2 Beta-lactamase 5.735e-34 0.77
BLAB_BACCE Metallo-beta-lactamase type 2 1.214e-32 0.37
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 1.172e-30 0.34
Q3S5C3_SALNE sugE Efflux transporter 2.03e-26 0.42
Q48435_KLEPN bla LAT-2 Beta-lactamase 2.03e-26 0.42
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 2.158e-24 0.30
BIRC2_HUMAN BIRC2 Baculoviral IAP repeat-containing protein 2 8.603e-22 0.32
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 7.228e-20 0.35
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 1.11e-16 0.31
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 2.687e-14 0.35
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.941e-12 0.35
AMPC_CITFR ampC Beta-lactamase 8.289e-12 0.29
BLAC_BACLI penP Beta-lactamase 8.289e-12 0.29
CATL1_RAT Ctsl Cathepsin L1 4.615e-11 0.35
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 5.367e-09 0.30
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 6.425e-08 0.30
AMPC_ECOLI ampC Beta-lactamase 4.107e-07 0.39
TF2AA_HUMAN GTF2A1 Transcription initiation factor IIA subunit 1 8.09e-06 0.28

Perhexiline

FYN_HUMAN FYN Tyrosine-protein kinase Fyn 0.01089 1.00
GPR55_HUMAN GPR55 G-protein coupled receptor 55 0.02848 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 0.06101 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.08099 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.1054 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.4304 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.5947 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.6272 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.7812 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9999 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 1 1.00
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 2.22e-16 0.32
Q6RY99_RAT Tetraspanin 4.393e-11 0.30
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 1.778e-08 0.33
PNMT_BOVIN PNMT Phenylethanolamine N-methyltransferase 2.466e-08 0.30
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 5.289e-07 0.33
M2_I000F M Matrix protein 2 6.705e-07 0.31

Doxepin

5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.01826 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.02581 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.3487 1.00
HRH1_CAVPO HRH1 Histamine H1 receptor 1.015e-30 0.76
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 1.222e-23 0.39
ASM_HUMAN SMPD1 Sphingomyelin phosphodiesterase 1.11e-16 0.42
HRH1_HUMAN HRH1 Histamine H1 receptor 1.023e-12 0.70
HRH1_RAT Hrh1 Histamine H1 receptor 2.123e-11 0.70
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 5.602e-10 0.46
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 1.214e-07 0.30
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.368e-07 0.40
UR2R_HUMAN UTS2R Urotensin-2 receptor 2.044e-07 0.35
DRD5_HUMAN DRD5 D(1B) dopamine receptor 4.906e-07 0.70
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 3.359e-06 0.70
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 4.303e-06 0.35
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 5.56e-06 0.70
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 5.934e-06 0.38

Tiludronic_acid

MMP2_HUMAN MMP2 72 kDa type IV collagenase 0.1028 1.00
GLNAC_MAIZE GLN2 Glutamine synthetase, chloroplastic 5.166e-42 0.33
P5CR1_ARATH PROC1 Pyrroline-5-carboxylate reductase 5.245e-27 0.33
Q01HZ7_ORYSA OSIGBa0132E09-OSIGBa0108L24.11 Glutamine synthetase 6.654e-21 0.33
MANR_PSEPU mdlA Mandelate racemase 1.523e-18 0.29
DXR_ECOLI dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3.945e-12 0.36
BLAB_AERHY cphA Metallo-beta-lactamase type 2 6.867e-12 0.38
EST1_RABIT Liver carboxylesterase 1 2.682e-10 0.34
BLA1_STEMA Metallo-beta-lactamase L1 type 3 3.365e-09 0.47
Q8MTZ4_9TRYP PPase1 Vacuolar-type proton translocating pyrophosphatase 1 1.717e-08 0.37
PPAP_HUMAN ACP3 Prostatic acid phosphatase 2.487e-08 0.31
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 3.295e-07 0.35
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 5.572e-06 0.41

Melatonin

MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 1.377e-314 0.83
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 3.725e-283 0.76
SYUA_HUMAN SNCA Alpha-synuclein 4.972e-152 0.58
SPRE_HUMAN SPR Sepiapterin reductase 3.358e-120 0.57
5HT1D_PIG HTR1D 5-hydroxytryptamine receptor 1D 7.432e-120 0.43
MTR1C_XENLA mtnr1c Melatonin receptor type 1C 4.216e-115 0.68
MTR1B_CHICK Melatonin receptor type 1B 2.986e-95 0.42
FPRS1_MOUSE Fpr-s1 Formyl peptide receptor-related sequence 1 2.415e-86 0.32
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 1.575e-84 0.69
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 5.077e-71 0.54
PERM_HUMAN MPO Myeloperoxidase 3.023e-65 0.48
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 2.342e-60 0.53
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 1.604e-54 0.32
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 4.078e-52 0.33
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 2.819e-45 0.57
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 3.689e-43 0.36
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.906e-37 0.56
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 4.202e-34 0.45
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.095e-33 0.36
NMBR_HUMAN NMBR Neuromedin-B receptor 1.467e-33 0.41
DNMT1_MOUSE Dnmt1 DNA (cytosine-5)-methyltransferase 1 9.732e-32 0.31
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 1.415e-31 0.36
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 2.892e-31 0.41
CHLE_HUMAN BCHE Cholinesterase 7.13e-31 0.59
KI20A_HUMAN KIF20A Kinesin-like protein KIF20A 4.992e-30 0.34
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 5.462e-30 0.71
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 3.276e-29 0.31
GBRA1_RAT Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 1.794e-28 0.41
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 6.038e-28 0.41
Q8MI13_BOVIN 5htr1d 5-hydroxytryptamine 1D receptor 9.356e-28 0.36
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 9.779e-28 0.45
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 1.161e-27 0.52
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 1.824e-26 0.35
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 3.01e-26 0.31
GBRG2_RAT Gabrg2 Gamma-aminobutyric acid receptor subunit gamma-2 7.533e-26 0.41
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 8.932e-26 0.55
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.14e-25 0.53
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 2.058e-25 0.52
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 2.898e-25 0.39
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 5.697e-25 0.54
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 7.256e-25 0.44
5HT1D_RAT Htr1d 5-hydroxytryptamine receptor 1D 7.498e-25 0.44
ACES_HUMAN ACHE Acetylcholinesterase 3.567e-24 0.60
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 3.953e-24 0.56
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 1.109e-23 0.33
ACES_BOVIN ACHE Acetylcholinesterase 2.315e-22 0.49
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 2.54e-22 0.55
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 3.447e-20 0.64
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 3.979e-20 0.69
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 2.322e-19 0.31
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 2.503e-19 0.35
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 3.278e-19 0.31
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 5.302e-19 0.37
MDHM_PIG MDH2 Malate dehydrogenase, mitochondrial 5.329e-19 0.30
NK2R_RAT Tacr2 Substance-K receptor 8.99e-19 0.38
5HT1B_GORGO HTR1B 5-hydroxytryptamine receptor 1B 1.406e-18 0.36
AAKB2_HUMAN PRKAB2 5'-AMP-activated protein kinase subunit beta-2 9.771e-18 0.28
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.168e-17 0.42
GBRA5_RAT Gabra5 Gamma-aminobutyric acid receptor subunit alpha-5 1.469e-17 0.40
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.577e-17 0.31
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 2.482e-17 0.49
GBRB3_RAT Gabrb3 Gamma-aminobutyric acid receptor subunit beta-3 2.607e-17 0.40
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 4.911e-17 0.60
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.11e-16 0.42
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 2.22e-16 0.31
HDAC2_HUMAN HDAC2 Histone deacetylase 2 7.772e-16 0.35
PD1L1_HUMAN CD274 Programmed cell death 1 ligand 1 1.665e-15 0.33
COX2_HUMAN MT-CO2 Cytochrome c oxidase subunit 2 2.109e-15 0.29
THA_HUMAN THRA Thyroid hormone receptor alpha 3.664e-15 0.36
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 9.326e-15 0.29
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.044e-14 0.31
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 1.876e-14 0.31
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 2.898e-14 0.40
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 2.964e-14 0.56
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 3.586e-14 0.67
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 4.474e-14 0.62
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 8.671e-14 0.52
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 1.112e-13 0.40
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.152e-13 0.56
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 3.232e-13 0.52
Q5NGQ3_FRATT fabI Enoyl-[acyl-carrier-protein] reductase [NADH] 3.773e-13 0.32
DPOL_HHV11 DNA polymerase catalytic subunit 4.846e-13 0.28
DPOL_VZVD DNA polymerase catalytic subunit 4.846e-13 0.28
Q9JN24_ECOLX def Peptide deformylase 1.749e-12 0.62
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 1.897e-12 0.53
THB_HUMAN THRB Thyroid hormone receptor beta 2.17e-12 0.36
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 2.277e-12 0.71
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 3.517e-12 0.33
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 4.659e-12 0.41
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 9.593e-12 0.33
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 1.17e-11 0.28
TYTR_TRYCR TPR Trypanothione reductase 1.38e-11 0.61
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 1.99e-11 0.35
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.235e-11 0.57
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 2.821e-11 0.36
T23O_MOUSE Tdo2 Tryptophan 2,3-dioxygenase 3.126e-11 0.30
TAU_HUMAN MAPT Microtubule-associated protein tau 8.329e-11 0.39
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 8.569e-11 0.40
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 9.301e-11 0.32
EST1_RABIT Liver carboxylesterase 1 2.244e-10 0.33
TSHR_HUMAN TSHR Thyrotropin receptor 3.175e-10 0.29
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 3.544e-10 0.46
CLK3_HUMAN CLK3 Dual specificity protein kinase CLK3 7.739e-10 0.45
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 8.38e-10 0.45
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 8.404e-10 0.37
DRD2_RAT Drd2 D(2) dopamine receptor 8.982e-10 0.49
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 1.24e-09 0.36
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.251e-09 0.65
MTSI_SPISQ sssIM CPG DNA methylase 1.37e-09 0.30
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 2.119e-09 0.34
ERM_STREE erm rRNA adenine N-6-methyltransferase 2.494e-09 0.29
MOT4_HUMAN SLC16A3 Monocarboxylate transporter 4 3.598e-09 0.29
NK1R_HUMAN TACR1 Substance-P receptor 4.402e-09 0.40
KPYK_STAAR pyk Pyruvate kinase 4.526e-09 0.33
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4.578e-09 0.39
DDAH1_HUMAN DDAH1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 5.398e-09 0.32
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 6.11e-09 0.65
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 6.237e-09 0.29
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 1.238e-08 0.47
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 1.395e-08 0.29
CHLE_HORSE BCHE Cholinesterase 1.724e-08 0.57
BAZ2A_HUMAN BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 2.819e-08 0.29
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 3.505e-08 0.29
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 3.887e-08 0.40
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 3.961e-08 0.36
DPOL_HHV6U U38 DNA polymerase catalytic subunit 3.985e-08 0.29
ACES_ELEEL ache Acetylcholinesterase 5.572e-08 0.57
Q7ZJM1_9HIV1 pol Integrase 5.656e-08 0.33
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 6.405e-08 0.36
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 7.169e-08 0.34
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 7.544e-08 0.34
HISX_BRAOC HDH Histidinol dehydrogenase, chloroplastic 7.964e-08 0.29
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 8.616e-08 0.36
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 1.022e-07 0.32
MAPK2_HUMAN MAPKAPK2 MAP kinase-activated protein kinase 2 1.098e-07 0.36
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 1.101e-07 0.30
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 1.162e-07 0.28
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1.272e-07 0.45
GPR84_HUMAN GPR84 G-protein coupled receptor 84 1.363e-07 0.60
BAZ2B_HUMAN BAZ2B Bromodomain adjacent to zinc finger domain protein 2B 1.488e-07 0.29
STE24_YEAST STE24 CAAX prenyl protease 1 1.805e-07 0.31
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.895e-07 0.51
ECE1_RAT Ece1 Endothelin-converting enzyme 1 4.034e-07 0.30
Q9WTR4_RAT Slc6a2 Transporter 5.135e-07 0.52
AAKG1_HUMAN PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 6.172e-07 0.34
HDAC6_HUMAN HDAC6 Histone deacetylase 6 8.215e-07 0.36
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 9.518e-07 0.38
AHR_HUMAN AHR Aryl hydrocarbon receptor 1.005e-06 0.46
NEP_RABIT MME Neprilysin 1.102e-06 0.34
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 1.102e-06 0.30
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 1.205e-06 0.33
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 1.223e-06 0.63
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.24e-06 0.29
TLR4_MOUSE Tlr4 Toll-like receptor 4 1.709e-06 0.30
RYR2_HUMAN RYR2 Ryanodine receptor 2 1.939e-06 0.32
OX2R_HUMAN HCRTR2 Orexin receptor type 2 2.036e-06 0.47
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 2.609e-06 0.45
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 2.754e-06 0.52
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.57e-06 0.52
GRIA1_RAT Gria1 Glutamate receptor 1 3.894e-06 0.30
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 5.411e-06 0.29
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 6.368e-06 0.36
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 7.02e-06 0.41
HDAC8_HUMAN HDAC8 Histone deacetylase 8 7.631e-06 0.34
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 8.023e-06 0.34
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 8.152e-06 0.29
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 8.209e-06 0.37
DRD3_HUMAN DRD3 D(3) dopamine receptor 8.94e-06 0.52
ADA2B_RAT Adra2b Alpha-2B adrenergic receptor 9.662e-06 0.31

Trimetrexate

DYR_RAT Dhfr Dihydrofolate reductase 4.78e-211 0.78
DRTS_TOXGO Bifunctional dihydrofolate reductase-thymidylate synthase 4.2e-204 0.78
DYR_PNECA Dihydrofolate reductase 2.266e-193 0.78
O30463_MYCAV folA Dihydrofolate reductase 1.199e-178 0.68
DYR_HUMAN DHFR Dihydrofolate reductase 5.688e-140 0.74
DYR_CANAX DFR1 Dihydrofolate reductase 7.958e-111 0.53
DYR_YEAST DFR1 Dihydrofolate reductase 6.405e-101 0.62
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 6.507e-99 0.58
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 1.232e-95 0.51
DYR_ENTFC folA Dihydrofolate reductase 3.499e-94 0.49
Q9UUP5_PNEJI DHFR DHFR 9.487e-94 0.40
Q81R22_BACAN dfrA Dihydrofolate reductase 1.457e-87 0.40
DYR_ECOLI folA Dihydrofolate reductase 1.097e-86 0.68
DYR_STAAU folA Dihydrofolate reductase 1.484e-85 0.43
DCPS_HUMAN DCPS m7GpppX diphosphatase 1.761e-71 0.44
DYR_LACCA folA Dihydrofolate reductase 1.71e-66 0.68
DYR_LACLA folA Dihydrofolate reductase 6.743e-51 0.39
KS6A2_MOUSE Rps6ka2 Ribosomal protein S6 kinase alpha-2 1.174e-39 0.32
DRTS_PLABA Bifunctional dihydrofolate reductase-thymidylate synthase 4.897e-35 0.42
Q8Z9J9_SALTI folA Dihydrofolate reductase 7.836e-31 0.39
O97467_PLAFA ht1 Hexose transporter 1 1.756e-28 0.53
DRTS_PLAFK Bifunctional dihydrofolate reductase-thymidylate synthase 7.396e-28 0.52
O61059_LEIME LmGT2 Glucose transporter 2.018e-27 0.53
DYR_MOUSE Dhfr Dihydrofolate reductase 3.995e-26 0.39
J7IFZ2_STRPY Dihydrofolate reductase 5.707e-26 0.30
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 7.174e-25 0.54
M3K11_MOUSE Map3k11 Mitogen-activated protein kinase kinase kinase 11 8.424e-24 0.32
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 2.957e-23 0.53
DYR1_ECOLX dhfrI Dihydrofolate reductase type 1 6.747e-23 0.39
DRTS_LEIMA Bifunctional dihydrofolate reductase-thymidylate synthase 1.303e-22 0.46
DYR_MYCTU folA Dihydrofolate reductase 3.093e-22 0.32
DYR_NEIGO folA Dihydrofolate reductase 2.022e-18 0.39
PTR1_LEIMA PTR1 Pteridine reductase 1 2.22e-16 0.46
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 7.437e-13 0.40
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 3.032e-10 0.32
FOLC_HUMAN FPGS Folylpolyglutamate synthase, mitochondrial 9.219e-07 0.35
PLCB_HUMAN AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 2.502e-06 0.29
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 3.815e-06 0.36
M3K11_HUMAN MAP3K11 Mitogen-activated protein kinase kinase kinase 11 9.018e-06 0.32
PDPK1_HUMAN PDPK1 3-phosphoinositide-dependent protein kinase 1 9.464e-06 0.34

Dihydrotachysterol

VDR_HUMAN VDR Vitamin D3 receptor 1.444e-181 0.54
VDR_RAT Vdr Vitamin D3 receptor 6.259e-157 0.44
VDR_BOVIN VDR Vitamin D3 receptor 4.192e-104 0.42
VDR_CHICK VDR Vitamin D3 receptor 1.844e-87 0.41
VDRA_DANRE vdra Vitamin D3 receptor A 3.256e-73 0.41
VDR_PIG VDR Vitamin D3 receptor 6.625e-51 0.41
VTDB_HUMAN GC Vitamin D-binding protein 6.625e-51 0.41
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 6.915e-34 0.45
DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 1.335e-19 0.31
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 7.022e-12 0.38
NR1H4_MOUSE Nr1h4 Bile acid receptor 4.32e-08 0.39
RXRA_MOUSE Rxra Retinoic acid receptor RXR-alpha 8.356e-07 0.39

Dinoprost_tromethamine

PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 2.829e-162 0.85
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 1.385e-117 0.85
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 1.592e-113 0.85
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 1.054e-112 0.85
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 6.554e-103 0.85
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 1.907e-84 0.85
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 3.22e-60 0.58
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 2.138e-53 0.58
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 3.139e-46 0.85
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 1.034e-39 0.58
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 7.165e-39 0.85
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 5.822e-38 0.85
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 1.116e-36 0.58
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 2.045e-35 0.58
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 1.98e-29 0.85
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 2.666e-29 0.85
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 1.167e-24 0.38
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 1.443e-24 0.29
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 6.571e-23 0.29
PI2R_HUMAN PTGIR Prostacyclin receptor 4.078e-21 0.58
SPTC2_HUMAN SPTLC2 Serine palmitoyltransferase 2 6.654e-21 0.33
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.537e-19 0.58
TA2R_RAT Tbxa2r Thromboxane A2 receptor 2.805e-17 0.59
KAPCA_RAT Prkaca cAMP-dependent protein kinase catalytic subunit alpha 7.438e-15 0.28
CNR1_RAT Cnr1 Cannabinoid receptor 1 9.37e-14 0.37
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.55e-13 0.32
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 8.017e-12 0.29
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 1.332e-11 0.36
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 1.661e-11 0.85
MGLL_RAT Mgll Monoglyceride lipase 5.806e-11 0.32
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 6.534e-11 0.58
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.027e-10 0.36
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 1.091e-10 0.32
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 1.295e-09 0.58
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 3.526e-08 0.30
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 2.697e-07 0.38
GLCM_MOUSE Gba Lysosomal acid glucosylceramidase 8.204e-07 0.30
GPR18_HUMAN GPR18 N-arachidonyl glycine receptor 8.63e-07 0.31

Arbutamine

ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 1.227e-130 0.61
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.202e-126 0.56
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 1.161e-113 0.61
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 4.752e-103 0.53
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 9.143e-68 0.48
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 2.58e-61 0.48
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 1.112e-59 0.35
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 2.14e-54 0.55
ADA2A_MOUSE Adra2a Alpha-2A adrenergic receptor 9.185e-54 0.43
ADA2C_MOUSE Adra2c Alpha-2C adrenergic receptor 9.185e-54 0.43
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 5.937e-51 0.48
H9TVJ1_CHISP TyR1 1.127e-50 0.33
TYTR_CRIFA TPR Trypanothione reductase 2.856e-49 0.39
GRIA1_RAT Gria1 Glutamate receptor 1 9.638e-47 0.31
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 1.599e-46 0.48
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 4.236e-33 0.39
GRIA1_HUMAN GRIA1 Glutamate receptor 1 7.704e-29 0.32
ARP19_RAT Arpp19 cAMP-regulated phosphoprotein 19 8.092e-26 0.32
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 5.257e-25 0.39
NANA_STREE nanA Sialidase A 6.246e-22 0.34
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 5.933e-21 0.55
Q39829_SOYBN Lipoxygenase 1.446e-19 0.31
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 4.687e-19 0.50
G3HDX1_CRIGR Alpha-1B adrenergic receptor 1.882e-17 0.33
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 1.11e-16 0.32
PA_I000X PA Polymerase acidic protein 1.887e-15 0.29
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 1.998e-15 0.32
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 4.441e-15 0.36
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.144e-14 0.48
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.354e-14 0.29
POLG_CXB3N Genome polyprotein 4.219e-14 0.35
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 5.118e-14 0.32
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 7.661e-14 0.34
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 1.261e-12 0.32
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 2.182e-12 0.40
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 3.546e-11 0.49
SCNNA_HUMAN SCNN1A Amiloride-sensitive sodium channel subunit alpha 3.173e-10 0.30
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 4.337e-10 0.54
TAT_HV1H2 tat Protein Tat 8.972e-10 0.28
AK1A1_HUMAN AKR1A1 Aldo-keto reductase family 1 member A1 1.498e-09 0.32
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 2.902e-09 0.49
COMT_PIG COMT Catechol O-methyltransferase 3.598e-09 0.29
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.643e-08 0.48
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 2.047e-08 0.48
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.925e-07 0.35
EGFR_MOUSE Egfr Epidermal growth factor receptor 2.788e-07 0.30
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 2.8e-07 0.49
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 4.905e-07 0.29
ESR2_RAT Esr2 Estrogen receptor beta 5.231e-07 0.29
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 7.476e-07 0.29
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.099e-06 0.45
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 1.848e-06 0.50
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 2.361e-06 0.30
LEF_BACAN lef Lethal factor 3.918e-06 0.33
DPOLB_RAT Polb DNA polymerase beta 4.596e-06 0.29
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 5.525e-06 0.30
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 5.525e-06 0.30

Deslanoside

AT1A1_HUMAN ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 2.463e-122 0.79
AT1A3_RAT Atp1a3 Sodium/potassium-transporting ATPase subunit alpha-3 8.134e-111 0.79
NOTC1_MOUSE Notch1 Neurogenic locus notch homolog protein 1 5.279e-104 0.58
AT1A2_RAT Atp1a2 Sodium/potassium-transporting ATPase subunit alpha-2 2.902e-100 0.79
AT1A1_CANLF ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 5.385e-89 0.79
SO4C1_HUMAN SLCO4C1 Solute carrier organic anion transporter family member 4C1 8.129e-75 0.65
AT1B3_RAT Atp1b3 Sodium/potassium-transporting ATPase subunit beta-3 3.253e-58 0.46
AT1A4_RAT Atp1a4 Sodium/potassium-transporting ATPase subunit alpha-4 7.167e-52 0.79
AT1B1_RAT Atp1b1 Sodium/potassium-transporting ATPase subunit beta-1 7.167e-52 0.79
AT1A1_PIG ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 1.009e-46 0.29
AT1A1_RAT Atp1a1 Sodium/potassium-transporting ATPase subunit alpha-1 2.636e-37 0.46
AMYP_HUMAN AMY2A Pancreatic alpha-amylase 1.366e-36 0.31
LEG4_HUMAN LGALS4 Galectin-4 5.046e-36 0.30
LEG8_HUMAN LGALS8 Galectin-8 5.046e-36 0.30
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 4.504e-35 0.79
AT12A_HUMAN ATP12A Potassium-transporting ATPase alpha chain 2 9.36e-26 0.44
NOTC1_HUMAN NOTCH1 Neurogenic locus notch homolog protein 1 1.128e-12 0.35
TYRO_HUMAN TYR Tyrosinase 1.032e-11 0.29
FGF1_HUMAN FGF1 Fibroblast growth factor 1 1.69e-08 0.28
PAX8_HUMAN PAX8 Paired box protein Pax-8 1.76e-07 0.88
KLF5_HUMAN KLF5 Krueppel-like factor 5 1.1e-06 0.46
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 2.659e-06 0.79
IL2_HUMAN IL2 Interleukin-2 3.059e-06 0.33
RORG_MOUSE Rorc Nuclear receptor ROR-gamma 4.532e-06 0.79

Nefazodone

5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 2.087e-117 0.51
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 2.533e-109 0.51
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.87e-106 0.50
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 6.634e-72 0.50
DRD2_HUMAN DRD2 D(2) dopamine receptor 6.675e-72 0.48
DRD3_HUMAN DRD3 D(3) dopamine receptor 4.162e-60 0.48
DRD2_RAT Drd2 D(2) dopamine receptor 8.885e-57 0.51
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 6.962e-52 0.48
DRD4_RAT Drd4 D(4) dopamine receptor 1.415e-50 0.48
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.907e-46 0.43
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 3.716e-41 0.49
HRH1_HUMAN HRH1 Histamine H1 receptor 5.884e-36 0.47
HRH3_HUMAN HRH3 Histamine H3 receptor 4.999e-34 0.40
NORA_STAAU norA Quinolone resistance protein NorA 3.951e-33 0.33
DRD3_RAT Drd3 D(3) dopamine receptor 1.151e-32 0.40
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 3.817e-32 0.35
DRD5_HUMAN DRD5 D(1B) dopamine receptor 5.587e-32 0.38
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.241e-31 0.44
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 2.103e-31 0.33
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 4.982e-30 0.40
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 4.51e-28 0.42
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 4.638e-26 0.34
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 2.069e-25 0.31
MYT1_HUMAN MYT1 Myelin transcription factor 1 1.605e-23 0.29
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 2.894e-23 0.44
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 8.185e-23 0.44
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.424e-22 0.38
HRH3_CAVPO HRH3 Histamine H3 receptor 1.502e-22 0.39
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 7.144e-22 0.40
DRD1_PIG DRD1 D(1A) dopamine receptor 1.073e-19 0.34
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 5.403e-19 0.51
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 6.46e-19 0.48
HRH3_RAT Hrh3 Histamine H3 receptor 7.418e-19 0.34
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 1.328e-18 0.36
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 2.388e-18 0.41
SL9A3_RAT Slc9a3 Sodium/hydrogen exchanger 3 2.873e-18 0.33
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 3.781e-18 0.46
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 5.457e-18 0.48
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 5.526e-18 0.35
H10_HUMAN H1-0 Histone H1.0 1.187e-17 0.34
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 2.053e-17 0.47
ADA1B_MOUSE Adra1b Alpha-1B adrenergic receptor 1.11e-16 0.32
Q9HUN3_PSEAE dnaB Replicative DNA helicase 6.661e-16 0.35
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 8.882e-16 0.46
ACES_ELEEL ache Acetylcholinesterase 5.107e-15 0.34
CHLE_HORSE BCHE Cholinesterase 1.044e-14 0.35
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 1.31e-14 0.32
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 1.91e-14 0.34
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 7.716e-14 0.30
HRH2_HUMAN HRH2 Histamine H2 receptor 1.13e-13 0.44
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 1.162e-13 0.31
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 1.592e-13 0.32
B2LA1_MOUSE Bcl2a1 Bcl-2-related protein A1 3.66e-13 0.35
KHK_HUMAN KHK Ketohexokinase 5.244e-13 0.32
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 1.096e-12 0.35
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.668e-12 0.35
B2LA1_HUMAN BCL2A1 Bcl-2-related protein A1 1.792e-12 0.32
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 3.986e-12 0.30
HRH1_CAVPO HRH1 Histamine H1 receptor 4.168e-12 0.35
HRP1_PLAFA Histidine-rich protein PFHRP-II 6.411e-12 0.32
DRD2_BOVIN DRD2 D(2) dopamine receptor 2.849e-11 0.31
IKKB_MOUSE Ikbkb Inhibitor of nuclear factor kappa-B kinase subunit beta 3.299e-11 0.31
DRD1_RAT Drd1 D(1A) dopamine receptor 1.015e-10 0.44
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.067e-10 0.31
AGTRB_RAT Agtr1b Type-1B angiotensin II receptor 2.221e-10 0.33
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 2.264e-10 0.48
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 7.622e-10 0.32
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 8.26e-10 0.31
REV1_HUMAN REV1 DNA repair protein REV1 9.011e-10 0.37
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.302e-09 0.33
V1BR_RAT Avpr1b Vasopressin V1b receptor 1.993e-09 0.34
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.384e-09 0.46
PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 4.412e-09 0.31
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 6.125e-09 0.33
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 6.265e-09 0.44
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 1.187e-08 0.32
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 1.425e-08 0.34
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 1.62e-08 0.34
SRC_MOUSE Src Neuronal proto-oncogene tyrosine-protein kinase Src 5.098e-08 0.29
CXCR1_HUMAN CXCR1 C-X-C chemokine receptor type 1 6.183e-08 0.38
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 7.859e-08 0.34
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 8.297e-08 0.36
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 1.017e-07 0.34
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 1.111e-07 0.31
ESR1_HUMAN ESR1 Estrogen receptor 1.116e-07 0.37
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 1.636e-07 0.37
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 2.152e-07 0.38
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 2.206e-07 0.39
ACES_RAT Ache Acetylcholinesterase 2.463e-07 0.34
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 3.619e-07 0.33
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 4.593e-07 0.36
Q9RMI3_STAAU fabI Enoyl-[acyl-carrier-protein] reductase [NADPH] 5.184e-07 0.29
DPO3_BACSU polC DNA polymerase III PolC-type 5.485e-07 0.31
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 8.058e-07 0.29
PRIO_SHEEP PRNP Major prion protein 1.025e-06 0.31
Q56D28_CAVPO CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells 1.106e-06 0.28
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 1.182e-06 0.29
O97467_PLAFA ht1 Hexose transporter 1 1.513e-06 0.36
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 1.677e-06 0.29
PDIA1_HUMAN P4HB Protein disulfide-isomerase 1.815e-06 0.29
ESR2_HUMAN ESR2 Estrogen receptor beta 2.878e-06 0.37
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 3.669e-06 0.36
DRD1_MOUSE Drd1 D(1A) dopamine receptor 3.977e-06 0.32
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 4.517e-06 0.32
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 5.069e-06 0.33
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 5.334e-06 0.35
DCTP1_HUMAN DCTPP1 dCTP pyrophosphatase 1 7.573e-06 0.32
O61059_LEIME LmGT2 Glucose transporter 9.145e-06 0.36
XDH_RAT Xdh Xanthine dehydrogenase/oxidase 9.278e-06 0.30
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 9.349e-06 0.29
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 9.621e-06 0.36

Glipizide

HYEP_MOUSE Ephx1 Epoxide hydrolase 1 3.034e-109 0.47
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 6.134e-76 0.47
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 1.786e-50 0.35
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 3.582e-45 0.30
Q9TU16_CANLF PTGER4 Prostaglandin E receptor 4 1.857e-33 0.42
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.156e-29 0.47
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 4.403e-25 0.41
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 8.436e-25 0.47
ABCC8_HUMAN ABCC8 ATP-binding cassette sub-family C member 8 4.406e-24 0.59
ABCBB_RAT Abcb11 Bile salt export pump 1.539e-23 0.59
TGM2_MOUSE Tgm2 Protein-glutamine gamma-glutamyltransferase 2 1.17e-22 0.36
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 5.211e-21 0.34
CAH1_HUMAN CA1 Carbonic anhydrase 1 5.989e-18 0.48
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 4.687e-17 0.59
CNR1_HUMAN CNR1 Cannabinoid receptor 1 2.22e-16 0.38
CAH2_HUMAN CA2 Carbonic anhydrase 2 3.331e-16 0.48
GPBAR_MOUSE Gpbar1 G-protein coupled bile acid receptor 1 5.551e-16 0.34
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 3.22e-15 0.59
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 5.329e-15 0.41
CAH4_BOVIN CA4 Carbonic anhydrase 4 4.015e-13 0.37
Q4Q5S8_LEIMA NMT Glycylpeptide N-tetradecanoyltransferase 4.482e-13 0.32
Q388H8_TRYB2 Glycylpeptide N-tetradecanoyltransferase 7.399e-13 0.32
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.964e-12 0.40
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 2.223e-12 0.37
ADA17_MOUSE Adam17 Disintegrin and metalloproteinase domain-containing protein 17 2.847e-12 0.30
CAH9_HUMAN CA9 Carbonic anhydrase 9 3.525e-12 0.48
Q9ERT1_MOUSE TRH-R2 Thyrotropin-releasing hormone receptor 2 4.181e-12 0.30
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 8.04e-12 0.30
CNR2_HUMAN CNR2 Cannabinoid receptor 2 8.762e-12 0.33
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 9.469e-12 0.37
TRFR_MOUSE Trhr Thyrotropin-releasing hormone receptor 1.216e-11 0.30
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 1.389e-11 0.33
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 1.571e-11 0.33
CAH14_HUMAN CA14 Carbonic anhydrase 14 2.996e-11 0.34
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 7.526e-11 0.29
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 8.353e-11 0.40
NMT1_HUMAN NMT1 Glycylpeptide N-tetradecanoyltransferase 1 1.439e-10 0.32
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 1.85e-10 0.33
CPNS1_PIG CAPNS1 Calpain small subunit 1 3.026e-10 0.28
CAH12_HUMAN CA12 Carbonic anhydrase 12 4.303e-10 0.48
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 5.554e-10 0.35
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 8.499e-10 0.34
ERG_HUMAN ERG Transcriptional regulator ERG 1.072e-09 0.28
PANC_MYCTU panC Pantothenate synthetase 6.08e-09 0.36
CAH2_BOVIN CA2 Carbonic anhydrase 2 6.404e-09 0.34
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.414e-08 0.40
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.494e-08 0.34
CAH7_HUMAN CA7 Carbonic anhydrase 7 3.552e-08 0.34
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 4.612e-08 0.40
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.581e-07 0.42
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.599e-07 0.33
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 2.033e-07 0.34
TYRO3_HUMAN TYRO3 Tyrosine-protein kinase receptor TYRO3 2.649e-07 0.32
GRM1_RAT Grm1 Metabotropic glutamate receptor 1 5.722e-07 0.38
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 6.005e-07 0.38
QPCTL_HUMAN QPCTL Glutaminyl-peptide cyclotransferase-like protein 7.32e-07 0.32
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 8.676e-07 0.31
MMP3_HUMAN MMP3 Stromelysin-1 8.932e-07 0.34
PRIO_MESAU PRNP Major prion protein 2.028e-06 0.29

Phenacemide

GLSK_HUMAN GLS Glutaminase kidney isoform, mitochondrial 4.777e-103 0.46
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 2.262e-71 0.44
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 1.275e-61 0.34
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 1.499e-60 0.33
FURIN_HUMAN FURIN Furin 2.655e-58 0.39
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 7.536e-58 0.43
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 3.616e-54 0.37
NEP_MOUSE Mme Neprilysin 1.479e-53 0.35
AOC2_HUMAN AOC2 Retina-specific copper amine oxidase 5.509e-53 0.38
AMPB_RAT Rnpep Aminopeptidase B 6.514e-53 0.31
GP183_MOUSE Gpr183 G-protein coupled receptor 183 5.108e-48 0.33
NEP_RABIT MME Neprilysin 7.065e-48 0.35
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 1.541e-47 0.32
GLSL_MOUSE Gls2 Glutaminase liver isoform, mitochondrial 3.737e-47 0.38
NK1R_RAT Tacr1 Substance-P receptor 3.56e-46 0.44
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 4.914e-46 0.37
CBPA1_HUMAN CPA1 Carboxypeptidase A1 1.448e-45 0.35
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 1.705e-44 0.37
AMPN_PIG ANPEP Aminopeptidase N 4.493e-44 0.37
GLT_PYRHO Glutamate transporter homolog 4.275e-43 0.34
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.531e-42 0.47
AMP1_PLAFQ M1 family aminopeptidase 2.021e-42 0.34
UBP4_HUMAN USP4 Ubiquitin carboxyl-terminal hydrolase 4 5.166e-42 0.33
Q99P97_RAT Histone deacetylase 6 4.048e-41 0.33
RCOR3_HUMAN RCOR3 REST corepressor 3 7.545e-40 0.32
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.244e-38 0.41
AMPB_MOUSE Rnpep Aminopeptidase B 1.947e-38 0.30
AMPL_BOVIN LAP3 Cytosol aminopeptidase 1.947e-38 0.30
SYL_STAA8 leuS Leucine--tRNA ligase 3.458e-38 0.30
NEP_RAT Mme Neprilysin 1.196e-37 0.36
PHHY_PSEFL pobA p-hydroxybenzoate hydroxylase 5.351e-37 0.29
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.479e-36 0.38
DAPAT_ARATH DAP LL-diaminopimelate aminotransferase, chloroplastic 1.572e-36 0.29
CBPC2_HUMAN AGBL2 Cytosolic carboxypeptidase 2 3.875e-36 0.29
AMPL_HUMAN LAP3 Cytosol aminopeptidase 5.287e-36 0.34
CBPA1_BOVIN CPA1 Carboxypeptidase A1 8.658e-35 0.37
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 1.908e-33 0.36
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 2.425e-33 0.35
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 4.943e-33 0.38
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.076e-32 0.39
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 1.468e-32 0.32
POLG_CXB3N Genome polyprotein 2.762e-30 0.46
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 2.887e-30 0.31
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 5.296e-30 0.37
NEP_PIG MME Neprilysin 9.685e-30 0.31
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 2.647e-29 0.38
Q7ZJM1_9HIV1 pol Integrase 4.003e-29 0.52
POLG_WNV Genome polyprotein 5.672e-29 0.33
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 4.738e-28 0.36
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 5.76e-28 0.34
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 5.76e-28 0.34
PHLC_BACCE plc Phospholipase C 1.055e-27 0.28
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 2.52e-27 0.43
AMPN_HUMAN ANPEP Aminopeptidase N 4.38e-27 0.36
UBP5_HUMAN USP5 Ubiquitin carboxyl-terminal hydrolase 5 5.245e-27 0.33
KYNU_HUMAN KYNU Kynureninase 4.802e-26 0.29
IL8_HUMAN CXCL8 Interleukin-8 5.111e-26 0.32
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 7.985e-26 0.33
BLAB_BACCE Metallo-beta-lactamase type 2 4.642e-25 0.28
EST1_RABIT Liver carboxylesterase 1 1.217e-24 0.39
SYL_ECOLI leuS Leucine--tRNA ligase 1.418e-24 0.30
HDAC8_HUMAN HDAC8 Histone deacetylase 8 5.714e-24 0.44
HMGB1_HUMAN HMGB1 High mobility group protein B1 5.518e-23 0.28
MGLL_RAT Mgll Monoglyceride lipase 9.952e-23 0.36
EST1_HUMAN CES1 Liver carboxylesterase 1 1.745e-22 0.54
Q6RY99_RAT Tetraspanin 1.796e-22 0.32
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 2.736e-22 0.40
AMPB_HUMAN RNPEP Aminopeptidase B 5.041e-22 0.32
A5H660_SCHMA HDAC8 Histone deacetylase 8 6.115e-22 0.35
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 1.058e-21 0.37
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.226e-21 0.46
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.866e-21 0.41
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.065e-21 0.41
HISX_ECOLI hisD Histidinol dehydrogenase 2.329e-21 0.34
THER_BACTH npr Thermolysin 6.533e-21 0.36
EPHB_MYCTO Epoxide hydrolase B 6.654e-21 0.33
HIS7_ECOLI hisB Histidine biosynthesis bifunctional protein HisB 8.763e-21 0.29
KLK8_HUMAN KLK8 Kallikrein-8 1.398e-20 0.29
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.578e-20 0.46
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 2.395e-20 0.33
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 7.273e-20 0.39
Q7K6A1_PLAF7 Histone deacetylase 7.563e-20 0.32
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 9.485e-20 0.33
GP183_HUMAN GPR183 G-protein coupled receptor 183 1.577e-19 0.33
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 3.691e-19 0.30
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 4.682e-19 0.38
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 4.893e-19 0.35
KLK4_HUMAN KLK4 Kallikrein-4 6.412e-19 0.29
VM1B1_BOTAS Snake venom metalloproteinase BaP1 9.052e-19 0.30
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.443e-18 0.59
Q9IP65_HCMV US28 G protein-coupled receptor 1.722e-18 0.35
LIPL_HUMAN LPL Lipoprotein lipase 2.139e-18 0.29
PA_I34A1 PA Polymerase acidic protein 2.415e-18 0.33
NEC2_HUMAN PCSK2 Neuroendocrine convertase 2 2.576e-18 0.29
VE1_HPV11 E1 Replication protein E1 2.805e-18 0.36
GNPAT_HUMAN GNPAT Dihydroxyacetone phosphate acyltransferase 4.879e-18 0.29
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 6.876e-18 0.34
BLA2_BACCE blm Metallo-beta-lactamase type 2 1.226e-17 0.36
ECE1_RAT Ece1 Endothelin-converting enzyme 1 1.315e-17 0.31
Q9SEH8_SOYBN Man1 alpha-1,2-Mannosidase 1.485e-17 0.29
PA_I000X PA Polymerase acidic protein 1.882e-17 0.33
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 4.539e-17 0.32
CAN_CANAL NCE103 Carbonic anhydrase 1.11e-16 0.39
CMA1_HUMAN CMA1 Chymase 1.11e-16 0.42
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 1.11e-16 0.40
MMP12_HUMAN MMP12 Macrophage metalloelastase 1.11e-16 0.36
CATL1_BOVIN CTSL Cathepsin L1 2.22e-16 0.30
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 2.22e-16 0.40
CAC1I_HUMAN CACNA1I Voltage-dependent T-type calcium channel subunit alpha-1I 3.331e-16 0.41
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 4.441e-16 0.37
AMPL_PIG LAP3 Cytosol aminopeptidase 5.551e-16 0.32
HISX_BRAOC HDH Histidinol dehydrogenase, chloroplastic 5.551e-16 0.34
KCNN4_HUMAN KCNN4 Intermediate conductance calcium-activated potassium channel protein 4 6.661e-16 0.30
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 9.992e-16 0.35
PPAP_HUMAN ACP3 Prostatic acid phosphatase 9.992e-16 0.31
NEP_HUMAN MME Neprilysin 1.221e-15 0.33
Q6FTL6_CANGA NCE103 Carbonic anhydrase 1.332e-15 0.33
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 1.443e-15 0.30
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 1.887e-15 0.37
PAPA1_CARPA Papain 2.109e-15 0.30
MALX3_YEAST IMA1 Oligo-1,6-glucosidase IMA1 2.22e-15 0.29
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 2.887e-15 0.35
CAH7_HUMAN CA7 Carbonic anhydrase 7 3.109e-15 0.46
CAH2_HUMAN CA2 Carbonic anhydrase 2 3.997e-15 0.46
LY96_HUMAN LY96 Lymphocyte antigen 96 4.441e-15 0.29
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 4.441e-15 0.29
H9B8T9_CAPHI CTSB Cathepsin B 4.774e-15 0.63
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 5.107e-15 0.36
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 5.107e-15 0.30
HDAC1_HUMAN HDAC1 Histone deacetylase 1 8.549e-15 0.41
EST2_HUMAN CES2 Cocaine esterase 1.01e-14 0.39
ELAS_PSEAE lasB Elastase 1.499e-14 0.34
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 1.71e-14 0.39
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 2.132e-14 0.33
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 2.132e-14 0.33
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 2.32e-14 0.36
CAH9_HUMAN CA9 Carbonic anhydrase 9 3.231e-14 0.46
CAH12_HUMAN CA12 Carbonic anhydrase 12 3.242e-14 0.46
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 4.285e-14 0.36
HDAC2_HUMAN HDAC2 Histone deacetylase 2 4.918e-14 0.44
ADH1G_HUMAN ADH1C Alcohol dehydrogenase 1C 5.851e-14 0.34
CAH1_HUMAN CA1 Carbonic anhydrase 1 7.105e-14 0.46
AOC3_HUMAN AOC3 Membrane primary amine oxidase 8.66e-14 0.38
HISX_BRUSU hisD Histidinol dehydrogenase 1.024e-13 0.34
LYAM1_HUMAN SELL L-selectin 1.433e-13 0.31
MMP8_HUMAN MMP8 Neutrophil collagenase 2.102e-13 0.36
PCSK7_HUMAN PCSK7 Proprotein convertase subtilisin/kexin type 7 2.482e-13 0.29
LAT1_RAT Slc7a5 Large neutral amino acids transporter small subunit 1 2.701e-13 0.29
BLA1_STEMA Metallo-beta-lactamase L1 type 3 2.808e-13 0.34
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 3.422e-13 0.36
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 3.768e-13 0.49
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 4.488e-13 0.34
US28_HCMVA US28 G-protein coupled receptor homolog US28 4.742e-13 0.35
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 7.938e-13 0.32
TYRO_MOUSE Tyr Tyrosinase 9.167e-13 0.31
RS27_HUMAN RPS27 40S ribosomal protein S27 1.465e-12 0.34
AMPX_VIBPR Bacterial leucyl aminopeptidase 1.88e-12 0.30
HDAC7_HUMAN HDAC7 Histone deacetylase 7 2.532e-12 0.33
MAP1_ECOLI map Methionine aminopeptidase 2.828e-12 0.35
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 3.725e-12 0.33
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 3.82e-12 0.30
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 4.628e-12 0.29
TRXR1_HUMAN TXNRD1 Thioredoxin reductase 1, cytoplasmic 5.743e-12 0.29
KLK2_HUMAN KLK2 Kallikrein-2 7.334e-12 0.29
GRM3_HUMAN GRM3 Metabotropic glutamate receptor 3 7.495e-12 0.33
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 9.93e-12 0.35
HRH1_CAVPO HRH1 Histamine H1 receptor 1.03e-11 0.38
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 1.29e-11 0.34
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.407e-11 0.59
FEN1_HUMAN FEN1 Flap endonuclease 1 1.464e-11 0.36
CBS_HUMAN CBS Cystathionine beta-synthase 1.659e-11 0.31
ASAH1_HUMAN ASAH1 Acid ceramidase 2.058e-11 0.31
AMPN_MOUSE Anpep Aminopeptidase N 2.506e-11 0.30
HDAC9_HUMAN HDAC9 Histone deacetylase 9 3.581e-11 0.33
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 3.972e-11 0.31
CATL1_HUMAN CTSL Cathepsin L1 5.096e-11 0.41
ADH1B_HUMAN ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH1B 7.128e-11 0.34
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 8.611e-11 0.31
PCSK6_HUMAN PCSK6 Proprotein convertase subtilisin/kexin type 6 1.005e-10 0.34
SSPA_STAAU sspA Glutamyl endopeptidase 1.105e-10 0.29
CTRA_BOVIN Chymotrypsinogen A 1.112e-10 0.31
SOAT1_CHLAE SOAT1 Sterol O-acyltransferase 1 1.182e-10 0.31
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 1.193e-10 0.39
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 1.284e-10 0.32
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 1.347e-10 0.32
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 1.381e-10 0.30
Q9JN24_ECOLX def Peptide deformylase 1.401e-10 0.30
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 1.441e-10 0.33
CRTM_STAAU crtM 4,4'-diapophytoene synthase 1.781e-10 0.29
CASP3_HUMAN CASP3 Caspase-3 1.848e-10 0.38
MMP2_HUMAN MMP2 72 kDa type IV collagenase 1.904e-10 0.38
KLK6_HUMAN KLK6 Kallikrein-6 2.006e-10 0.38
SCNNA_HUMAN SCNN1A Amiloride-sensitive sodium channel subunit alpha 2.83e-10 0.31
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 3.052e-10 0.41
HDA11_HUMAN HDAC11 Histone deacetylase 11 3.398e-10 0.35
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 3.663e-10 0.38
P2RX4_RAT P2rx4 P2X purinoceptor 4 3.926e-10 0.34
MCA2_TRYBB MCA2 Metacaspase 4.084e-10 0.29
LYAM3_HUMAN SELP P-selectin 4.375e-10 0.33
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 4.762e-10 0.34
PADI1_HUMAN PADI1 Protein-arginine deiminase type-1 4.884e-10 0.29
PADI3_HUMAN PADI3 Protein-arginine deiminase type-3 4.884e-10 0.29
S100B_HUMAN S100B Protein S100-B 4.884e-10 0.29
HDAC3_HUMAN HDAC3 Histone deacetylase 3 6.077e-10 0.41
CATK_RABIT CTSK Cathepsin K 6.253e-10 0.31
PTPRA_HUMAN PTPRA Receptor-type tyrosine-protein phosphatase alpha 6.505e-10 0.30
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 6.872e-10 0.47
MMP10_HUMAN MMP10 Stromelysin-2 7.828e-10 0.31
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 7.875e-10 0.33
MDM4_HUMAN MDM4 Protein Mdm4 8.742e-10 0.35
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 1.031e-09 0.32
MEP1B_HUMAN MEP1B Meprin A subunit beta 1.099e-09 0.34
UROK_HUMAN PLAU Urokinase-type plasminogen activator 1.186e-09 0.42
Q49PX0_9POXV N1L N1L 1.278e-09 0.34
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.37e-09 0.30
MMP1_HUMAN MMP1 Interstitial collagenase 1.558e-09 0.38
CAC1H_HUMAN CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H 1.754e-09 0.36
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 1.767e-09 0.35
BLAB_AERHY cphA Metallo-beta-lactamase type 2 2.039e-09 0.29
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 2.303e-09 0.31
PPCE_BOVIN PREP Prolyl endopeptidase 2.406e-09 0.29
RCOR1_HUMAN RCOR1 REST corepressor 1 2.558e-09 0.31
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 2.791e-09 0.29
AROK_HELPY aroK Shikimate kinase 2.903e-09 0.29
EST5_RAT Liver carboxylesterase B-1 3.304e-09 0.31
MMP8_RAT Mmp8 Neutrophil collagenase 3.598e-09 0.29
ACE_HUMAN ACE Angiotensin-converting enzyme 3.755e-09 0.35
HDAC5_HUMAN HDAC5 Histone deacetylase 5 3.982e-09 0.33
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 4.324e-09 0.29
SYLC_HUMAN LARS1 Leucine--tRNA ligase, cytoplasmic 4.635e-09 0.30
SCYD_MAGO7 SDH1 Scytalone dehydratase 5.315e-09 0.33
HCAR2_RAT Hcar2 Hydroxycarboxylic acid receptor 2 5.615e-09 0.30
NK2R_MESAU TACR2 Substance-K receptor 6.286e-09 0.34
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 6.704e-09 0.32
CLAT_RAT Chat Choline O-acetyltransferase 7.034e-09 0.37
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 7.399e-09 0.41
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 7.444e-09 0.32
PPO2_AGABI PPO2 Polyphenol oxidase 2 7.874e-09 0.40
CAH14_HUMAN CA14 Carbonic anhydrase 14 8.06e-09 0.46
THRB_HUMAN F2 Prothrombin 1.055e-08 0.39
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 1.203e-08 0.37
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 1.258e-08 0.34
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 1.322e-08 0.29
TRY1_RAT Prss1 Anionic trypsin-1 1.445e-08 0.29
UPAR_RAT Plaur Urokinase plasminogen activator surface receptor 1.445e-08 0.29
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.674e-08 0.32
MMP3_HUMAN MMP3 Stromelysin-1 1.857e-08 0.34
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 1.883e-08 0.34
FCER2_HUMAN FCER2 Low affinity immunoglobulin epsilon Fc receptor 1.916e-08 0.33
Q76353_9HIV1 Integrase 2.431e-08 0.41
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 2.451e-08 0.35
SOAT2_CHLAE SOAT2 Sterol O-acyltransferase 2 2.487e-08 0.31
AOC3_RAT Aoc3 Membrane primary amine oxidase 2.798e-08 0.38
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 2.905e-08 0.39
TRY1_HUMAN PRSS1 Trypsin-1 3.91e-08 0.34
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 3.985e-08 0.29
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 4.23e-08 0.41
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 5.883e-08 0.32
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 6.161e-08 0.32
CASP7_HUMAN CASP7 Caspase-7 6.239e-08 0.38
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 6.44e-08 0.29
PA21B_HUMAN PLA2G1B Phospholipase A2 6.502e-08 0.33
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 6.978e-08 0.29
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 7.027e-08 0.34
CAH3_HUMAN CA3 Carbonic anhydrase 3 8.482e-08 0.30
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 9.293e-08 0.36
AOC3_BOVIN AOC3 Membrane primary amine oxidase 1.031e-07 0.29
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.033e-07 0.31
NK3R_HUMAN TACR3 Neuromedin-K receptor 1.196e-07 0.37
ACE_RAT Ace Angiotensin-converting enzyme 1.642e-07 0.33
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 1.91e-07 0.30
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 1.91e-07 0.30
CAH4_BOVIN CA4 Carbonic anhydrase 4 2.323e-07 0.36
MCR_HUMAN NR3C2 Mineralocorticoid receptor 2.693e-07 0.40
Q72874_9HIV1 pol Pol polyprotein 2.84e-07 0.35
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 3.123e-07 0.38
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 3.222e-07 0.36
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 3.437e-07 0.32
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 3.465e-07 0.38
CATG_HUMAN CTSG Cathepsin G 3.485e-07 0.31
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 3.629e-07 0.29
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 3.793e-07 0.43
ACE_MOUSE Ace Angiotensin-converting enzyme 4.177e-07 0.29
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 4.192e-07 0.34
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 4.206e-07 0.30
SENP7_HUMAN SENP7 Sentrin-specific protease 7 4.712e-07 0.34
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 5.08e-07 0.28
Q8IL11_PLAF7 M17 leucyl aminopeptidase 5.223e-07 0.33
LIMK2_HUMAN LIMK2 LIM domain kinase 2 5.435e-07 0.31
TLR4_MOUSE Tlr4 Toll-like receptor 4 5.663e-07 0.31
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 6.257e-07 0.29
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 6.533e-07 0.43
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 6.565e-07 0.31
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 6.696e-07 0.31
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 7.045e-07 0.29
GRIA1_RAT Gria1 Glutamate receptor 1 7.147e-07 0.35
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 7.833e-07 0.31
PERM_HUMAN MPO Myeloperoxidase 8.114e-07 0.33
PEN2_HUMAN PSENEN Gamma-secretase subunit PEN-2 8.688e-07 0.35
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 8.985e-07 0.32
LYAM2_HUMAN SELE E-selectin 9.716e-07 0.33
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 1.125e-06 0.36
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 1.167e-06 0.36
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 1.241e-06 0.30
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 1.277e-06 0.29
EST1_PIG Liver carboxylesterase 1.326e-06 0.33
MAP1_YEAST MAP1 Methionine aminopeptidase 1 1.339e-06 0.35
CHLE_HUMAN BCHE Cholinesterase 1.415e-06 0.42
Q9ZTP8_MAIZE hd1b Histone deacetylase 1.423e-06 0.32
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 1.478e-06 0.38
COMT_RAT Comt Catechol O-methyltransferase 1.491e-06 0.33
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 1.507e-06 0.30
ADA_HUMAN ADA Adenosine deaminase 1.556e-06 0.29
APH1A_HUMAN APH1A Gamma-secretase subunit APH-1A 1.628e-06 0.35
APH1B_HUMAN APH1B Gamma-secretase subunit APH-1B 1.628e-06 0.35
NICA_HUMAN NCSTN Nicastrin 1.628e-06 0.35
PSN2_HUMAN PSEN2 Presenilin-2 1.67e-06 0.35
HDAC1_MOUSE Hdac1 Histone deacetylase 1 1.743e-06 0.32
KLK1_HUMAN KLK1 Kallikrein-1 1.85e-06 0.34
GRIA4_RAT Gria4 Glutamate receptor 4 2.005e-06 0.35
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 2.064e-06 0.30
NEUR3_HUMAN NEU3 Sialidase-3 2.088e-06 0.29
NR1H4_HUMAN NR1H4 Bile acid receptor 2.372e-06 0.38
B4URF0_I33A0 Neuraminidase 2.376e-06 0.34
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 2.417e-06 0.33
CAH6_HUMAN CA6 Carbonic anhydrase 6 2.866e-06 0.35
MAP2_HUMAN METAP2 Methionine aminopeptidase 2 2.954e-06 0.33
PSN1_HUMAN PSEN1 Presenilin-1 3.028e-06 0.35
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 3.035e-06 0.35
CAH13_HUMAN CA13 Carbonic anhydrase 13 3.092e-06 0.30
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 3.124e-06 0.31
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 3.24e-06 0.31
HRH2_CAVPO HRH2 Histamine H2 receptor 3.3e-06 0.38
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 3.536e-06 0.31
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 3.936e-06 0.34
STRP_STRP1 ska Streptokinase A 3.993e-06 0.41
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 4.252e-06 0.33
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 4.268e-06 0.44
OXDA_PIG DAO D-amino-acid oxidase 4.337e-06 0.32
HDAC4_HUMAN HDAC4 Histone deacetylase 4 4.343e-06 0.33
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 4.586e-06 0.30
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 4.928e-06 0.30
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 5.406e-06 0.40
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 5.548e-06 0.31
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 5.699e-06 0.32
AOFB_RAT Maob Amine oxidase [flavin-containing] B 5.956e-06 0.36
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 6.411e-06 0.30
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 6.947e-06 0.30
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 7.689e-06 0.30
PAO1_MAIZE MPAO1 Polyamine oxidase 1 8.819e-06 0.31
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 9.255e-06 0.34

Cefapirin

S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 1.371e-100 0.68
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 5.697e-62 0.68
B2ZTR6_ACIBA Beta-lactamase 9.298e-56 0.53
D6NSM8_ACIBA ampC Beta-lactamase 9.298e-56 0.53
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.206e-55 0.68
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 3.04e-35 0.44
Q59401_ENTCL Beta-lactamase 5.703e-27 0.37
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.435e-25 0.47
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 3.906e-19 0.37
A2RP81_CITFR blaPER-2 Beta-lactamase 3.088e-17 0.38
AMPC_ENTCL ampC Beta-lactamase 1.728e-13 0.43
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 1.312e-11 0.40
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 1.101e-09 0.30
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 5.627e-09 0.41
STRP_STRP1 ska Streptokinase A 8.398e-09 0.62
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1.042e-08 0.34
BLAC_STAAU blaZ Beta-lactamase 1.078e-08 0.31
BLAT_ECOLX bla; blaT-3; blaT-4; blaT-5; blaT-6 Beta-lactamase TEM 2.094e-08 0.37
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 1.038e-07 0.68
ELNE_HUMAN ELANE Neutrophil elastase 1.318e-06 0.44
Q6W9J1_ENTCL blaTEM-1 Beta-lactamase 2.473e-06 0.29

Cefditoren

PBPA_PSEAE mrcA Penicillin-binding protein 1A 7.137e-86 0.40
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 7.44e-74 0.65
B2ZTR6_ACIBA Beta-lactamase 1.481e-64 0.65
D6NSM8_ACIBA ampC Beta-lactamase 1.481e-64 0.65
Q83TT7_ECOLX ampC AmpC 3.15e-58 0.40
Q7DHH4_STAAU mecA MecA 5.341e-50 0.40
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.447e-45 0.65
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 3.268e-41 0.65
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 1.376e-32 0.40
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 1.335e-27 0.34
Q3S5C3_SALNE sugE Efflux transporter 3.477e-25 0.40
Q48435_KLEPN bla LAT-2 Beta-lactamase 3.477e-25 0.40
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.44e-18 0.34
A2RP81_CITFR blaPER-2 Beta-lactamase 2.987e-18 0.40
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 2.866e-17 0.33
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.109e-15 0.63
AMPC_CITFR ampC Beta-lactamase 2.573e-13 0.33
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 3.404e-13 0.62
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 1.069e-06 0.63
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 9.675e-06 0.62

Tolbutamide

AKT1_MOUSE Akt1 RAC-alpha serine/threonine-protein kinase 6.237e-78 0.32
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 1.67e-49 0.43
SYL_STAA8 leuS Leucine--tRNA ligase 1.083e-43 0.35
LN28A_MOUSE Lin28a Protein lin-28 homolog A 6.889e-43 0.34
ASAH1_RAT Asah1 Acid ceramidase 1.112e-42 0.34
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 6.691e-41 0.34
PA2A1_NAJMO Acidic phospholipase A2 CM-I 9.952e-40 0.31
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 5.824e-38 0.43
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 6.761e-37 0.60
Q9TU16_CANLF PTGER4 Prostaglandin E receptor 4 2.774e-36 0.45
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 5.892e-35 0.55
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 7.937e-34 0.50
FFAR4_RAT Ffar4 Free fatty acid receptor 4 4.951e-31 0.32
MEP1B_HUMAN MEP1B Meprin A subunit beta 9.93e-30 0.33
SYL_ECOLI leuS Leucine--tRNA ligase 4.494e-28 0.35
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 5.006e-25 0.41
CAH2_HUMAN CA2 Carbonic anhydrase 2 7.526e-25 0.61
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 8.255e-25 0.34
Q26964_TRYCR TCTS-154 Trans-sialidase 8.615e-25 0.31
CAH1_HUMAN CA1 Carbonic anhydrase 1 3.679e-23 0.61
CEL_BOVIN CEL Bile salt-activated lipase 1.201e-22 0.35
CAH9_HUMAN CA9 Carbonic anhydrase 9 5.089e-22 0.61
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.745e-21 0.61
MMP2_HUMAN MMP2 72 kDa type IV collagenase 6.164e-19 0.45
S22A8_RAT Slc22a8 Solute carrier family 22 member 8 2.139e-18 0.29
CAN1_RAT Capn1 Calpain-1 catalytic subunit 2.879e-18 0.35
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.134e-17 0.38
MMP7_HUMAN MMP7 Matrilysin 1.11e-16 0.39
CAH4_BOVIN CA4 Carbonic anhydrase 4 2.22e-16 0.46
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 4.441e-16 0.45
ASAH1_HUMAN ASAH1 Acid ceramidase 1.11e-15 0.35
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.221e-15 0.50
CAH2_BOVIN CA2 Carbonic anhydrase 2 1.332e-15 0.38
GSP_CRIFA GSP Glutathionylspermidine synthase 1.776e-15 0.38
KMO_RAT Kmo Kynurenine 3-monooxygenase 7.772e-15 0.32
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.177e-14 0.48
TASP1_HUMAN TASP1 Threonine aspartase 1 1.621e-14 0.40
CXCR2_RABIT CXCR2 C-X-C chemokine receptor type 2 9.315e-14 0.34
ABCBB_RAT Abcb11 Bile salt export pump 9.504e-14 0.34
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 2.173e-13 0.29
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 5.702e-13 0.35
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 2.251e-12 0.45
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 2.96e-12 0.39
FA10_BOVIN F10 Coagulation factor X 3.875e-12 0.34
I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 4.776e-12 0.42
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 4.975e-12 0.45
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 5.407e-12 0.50
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 5.581e-12 0.30
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 5.918e-12 0.36
CAH7_HUMAN CA7 Carbonic anhydrase 7 1.173e-11 0.50
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 2.383e-11 0.40
MMP8_HUMAN MMP8 Neutrophil collagenase 2.573e-11 0.45
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 3.912e-11 0.36
MMP13_HUMAN MMP13 Collagenase 3 4.891e-11 0.39
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 1.124e-10 0.38
METC_ECOLI metC Cystathionine beta-lyase MetC 1.779e-10 0.42
SYLC_HUMAN LARS1 Leucine--tRNA ligase, cytoplasmic 2.78e-10 0.35
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 4.259e-10 0.36
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 4.398e-10 0.29
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 4.813e-10 0.34
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 4.884e-10 0.29
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 5.027e-10 0.31
ABCC8_HUMAN ABCC8 ATP-binding cassette sub-family C member 8 5.041e-10 0.34
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 6.343e-10 0.38
AGTR1_PIG AGTR1 Type-1 angiotensin II receptor 7.185e-10 0.32
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 8.894e-10 0.37
MMP3_HUMAN MMP3 Stromelysin-1 1.016e-09 0.39
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 1.166e-09 0.38
Q9JN24_ECOLX def Peptide deformylase 1.326e-09 0.32
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.395e-09 0.42
EST1_RABIT Liver carboxylesterase 1 1.508e-09 0.30
LIMK2_HUMAN LIMK2 LIM domain kinase 2 1.906e-09 0.36
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 2.184e-09 0.29
MMP12_HUMAN MMP12 Macrophage metalloelastase 2.757e-09 0.45
MMP1_HUMAN MMP1 Interstitial collagenase 3.131e-09 0.39
PLEC_HUMAN PLEC Plectin 3.275e-09 0.33
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 3.545e-09 0.34
LEF_BACAN lef Lethal factor 4.459e-09 0.38
RGS8_HUMAN RGS8 Regulator of G-protein signaling 8 5.367e-09 0.30
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 5.447e-09 0.34
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 6.17e-09 0.45
COLA_CLOPE colA Collagenase ColA 6.525e-09 0.38
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 1.709e-08 0.30
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 1.934e-08 0.48
CAN_CANAL NCE103 Carbonic anhydrase 2.212e-08 0.34
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.515e-08 0.33
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 3.608e-08 0.31
STS_HUMAN STS Steryl-sulfatase 3.9e-08 0.32
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 4.403e-08 0.33
DDAH1_HUMAN DDAH1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 4.589e-08 0.28
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 4.592e-08 0.35
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 5.768e-08 0.33
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 6.003e-08 0.34
O39930_9HEPC NS5b RNA-directed RNA polymerase 6.793e-08 0.32
MGLL_RAT Mgll Monoglyceride lipase 8.8e-08 0.33
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 9.141e-08 0.30
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 1.724e-07 0.32
F16P1_MOUSE Fbp1 Fructose-1,6-bisphosphatase 1 2.119e-07 0.29
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 2.423e-07 0.31
Q72874_9HIV1 pol Pol polyprotein 2.696e-07 0.38
Q6FTL6_CANGA NCE103 Carbonic anhydrase 3.6e-07 0.34
CAH4_HUMAN CA4 Carbonic anhydrase 4 4.144e-07 0.50
MAP2_HUMAN METAP2 Methionine aminopeptidase 2 5.031e-07 0.36
THRB_BOVIN F2 Prothrombin 7.066e-07 0.34
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 7.955e-07 0.30
Q8JXU8_9HEPC NS5B RNA-directed RNA polymerase 8.108e-07 0.41
PNMT_HUMAN PNMT Phenylethanolamine N-methyltransferase 1.041e-06 0.33
CAH6_HUMAN CA6 Carbonic anhydrase 6 1.29e-06 0.50
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 2.123e-06 0.29
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 2.123e-06 0.29
THRB_HUMAN F2 Prothrombin 2.593e-06 0.45
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 3.407e-06 0.40
HEPS_HUMAN HPN Serine protease hepsin 3.534e-06 0.31
RPGF4_HUMAN RAPGEF4 Rap guanine nucleotide exchange factor 4 3.803e-06 0.31
CAH3_HUMAN CA3 Carbonic anhydrase 3 3.813e-06 0.35
MCLN3_HUMAN MCOLN3 Mucolipin-3 3.924e-06 0.33
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 4.274e-06 0.34
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 4.874e-06 0.33
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 5.557e-06 0.29
O49150_SOLTU Lipoxygenase 5.734e-06 0.29
CPNS1_PIG CAPNS1 Calpain small subunit 1 6.867e-06 0.31
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 7.401e-06 0.30
CNR1_RAT Cnr1 Cannabinoid receptor 1 7.687e-06 0.35
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 9.419e-06 0.29

Doxacurium

S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 1.111e-76 0.37
TBB5_HUMAN TUBB Tubulin beta chain 1.444e-23 0.29
TPPP_BOVIN TPPP Tubulin polymerization-promoting protein 1.444e-23 0.29
ACHB4_MOUSE Chrnb4 Neuronal acetylcholine receptor subunit beta-4 5.286e-23 0.36
ACHB2_MOUSE Chrnb2 Neuronal acetylcholine receptor subunit beta-2 1.651e-21 0.36
ACPM_HUMAN NDUFAB1 Acyl carrier protein, mitochondrial 5.551e-16 0.30
CIA30_HUMAN NDUFAF1 Complex I intermediate-associated protein 30, mitochondrial 5.551e-16 0.30
NDUA1_HUMAN NDUFA1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 5.551e-16 0.30
NDUA2_HUMAN NDUFA2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 5.551e-16 0.30
NDUA3_HUMAN NDUFA3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 5.551e-16 0.30
NDUA5_HUMAN NDUFA5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 5.551e-16 0.30
NDUA6_HUMAN NDUFA6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 5.551e-16 0.30
NDUA7_HUMAN NDUFA7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 5.551e-16 0.30
NDUA8_HUMAN NDUFA8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 5.551e-16 0.30
NDUA9_HUMAN NDUFA9 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial 5.551e-16 0.30
NDUAA_HUMAN NDUFA10 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial 5.551e-16 0.30
NDUAB_HUMAN NDUFA11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 5.551e-16 0.30
NDUAC_HUMAN NDUFA12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 5.551e-16 0.30
NDUAD_HUMAN NDUFA13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 5.551e-16 0.30
NDUB1_HUMAN NDUFB1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 5.551e-16 0.30
NDUB2_HUMAN NDUFB2 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial 5.551e-16 0.30
NDUB3_HUMAN NDUFB3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 5.551e-16 0.30
NDUB4_HUMAN NDUFB4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 5.551e-16 0.30
NDUB5_HUMAN NDUFB5 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial 5.551e-16 0.30
NDUB6_HUMAN NDUFB6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 5.551e-16 0.30
NDUB7_HUMAN NDUFB7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 5.551e-16 0.30
NDUB8_HUMAN NDUFB8 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial 5.551e-16 0.30
NDUB9_HUMAN NDUFB9 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 5.551e-16 0.30
NDUBA_HUMAN NDUFB10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 5.551e-16 0.30
NDUBB_HUMAN NDUFB11 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial 5.551e-16 0.30
NDUC1_HUMAN NDUFC1 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial 5.551e-16 0.30
NDUC2_HUMAN NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2 5.551e-16 0.30
NDUF2_HUMAN NDUFAF2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 5.551e-16 0.30
NDUF3_HUMAN NDUFAF3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 5.551e-16 0.30
NDUF4_HUMAN NDUFAF4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 5.551e-16 0.30
NDUS1_HUMAN NDUFS1 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 5.551e-16 0.30
NDUS2_HUMAN NDUFS2 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 5.551e-16 0.30
NDUS3_HUMAN NDUFS3 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 5.551e-16 0.30
NDUS4_HUMAN NDUFS4 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 5.551e-16 0.30
NDUS5_HUMAN NDUFS5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 5.551e-16 0.30
NDUS6_HUMAN NDUFS6 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial 5.551e-16 0.30
NDUS7_HUMAN NDUFS7 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial 5.551e-16 0.30
NDUS8_HUMAN NDUFS8 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial 5.551e-16 0.30
NDUV1_HUMAN NDUFV1 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 5.551e-16 0.30
NDUV2_HUMAN NDUFV2 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 5.551e-16 0.30
NDUV3_HUMAN NDUFV3 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 5.551e-16 0.30
NU1M_HUMAN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 5.551e-16 0.30
NU2M_HUMAN MT-ND2 NADH-ubiquinone oxidoreductase chain 2 5.551e-16 0.30
NU3M_HUMAN MT-ND3 NADH-ubiquinone oxidoreductase chain 3 5.551e-16 0.30
NU4LM_HUMAN MT-ND4L NADH-ubiquinone oxidoreductase chain 4L 5.551e-16 0.30
NU5M_HUMAN MT-ND5 NADH-ubiquinone oxidoreductase chain 5 5.551e-16 0.30
NU6M_HUMAN MT-ND6 NADH-ubiquinone oxidoreductase chain 6 5.551e-16 0.30
NUA4L_HUMAN NDUFA4L2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 5.551e-16 0.30
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 2.017e-13 0.33
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 9.402e-13 0.37
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 1.973e-12 0.30
SC5A7_MOUSE Slc5a7 High affinity choline transporter 1 2.398e-12 0.29
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 4.835e-12 0.32
NU4M_HUMAN MT-ND4 NADH-ubiquinone oxidoreductase chain 4 2.015e-10 0.30
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 4.612e-08 0.32
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 8.805e-08 0.35
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 1.182e-07 0.37
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 1.295e-07 0.37
MIP_LEGPN mip Outer membrane protein MIP 2.571e-07 0.31
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 3.632e-07 0.34
KCNN3_RAT Kcnn3 Small conductance calcium-activated potassium channel protein 3 6.937e-07 0.63
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 1.226e-06 0.30
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.409e-06 0.29

Cefprozil

S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 6.783e-76 0.41
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 2.316e-60 0.76
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 3.476e-48 0.76
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 8.1e-47 0.41
Q7DHH4_STAAU mecA MecA 5.166e-42 0.33
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 2.873e-31 0.76
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 9.23e-26 0.50
B2ZTR6_ACIBA Beta-lactamase 2.329e-21 0.34
D6NSM8_ACIBA ampC Beta-lactamase 2.329e-21 0.34
CATL1_RAT Ctsl Cathepsin L1 7.216e-15 0.31
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 1.535e-11 0.39
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 3.968e-11 0.30
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.399e-09 0.37
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 3.497e-07 0.32
STRP_STRP1 ska Streptokinase A 1.775e-06 0.60
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 3.278e-06 0.60

Proflavine

TOP2_PLAFK TOP2 DNA topoisomerase 2 7.425e-75 0.45
MSRA_BOVIN MSRA Mitochondrial peptide methionine sulfoxide reductase 2.665e-15 0.29
RLGM1_TRYBB REL1 RNA-editing ligase 1, mitochondrial 6.761e-14 0.34
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 6.464e-12 0.29
REV_HV1H2 rev Protein Rev 6.501e-11 0.44
O40947_HHV8 ORF 73 9.262e-11 0.50
TGT_ZYMMO tgt Queuine tRNA-ribosyltransferase 5.367e-09 0.30
TAU_HUMAN MAPT Microtubule-associated protein tau 5.383e-08 0.50
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1.849e-07 0.29
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 1.849e-07 0.29
5NTD_HUMAN NT5E 5'-nucleotidase 3.948e-07 0.34
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 2.32e-06 0.29
TERT_HUMAN TERT Telomerase reverse transcriptase 5.668e-06 0.41
POLG_HCVNZ Genome polyprotein 6.946e-06 0.46

Prednicarbate

ATTY_RAT Tat Tyrosine aminotransferase 2.388e-65 0.31
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.206e-54 0.56
Q690N0_BOVIN PGR Progesterone receptor 1.351e-39 0.45
GCR_HUMAN NR3C1 Glucocorticoid receptor 5.777e-37 0.56
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.018e-35 0.56
GCR_RAT Nr3c1 Glucocorticoid receptor 6.64e-35 0.56
SHBG_HUMAN SHBG Sex hormone-binding globulin 2.785e-24 0.41
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 2.025e-20 0.33
CP19A_HUMAN CYP19A1 Aromatase 2.017e-19 0.41
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.558e-17 0.56
GLNA_HUMAN GLUL Glutamine synthetase 2.558e-17 0.56
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 3.775e-15 0.33
IL6_HUMAN IL6 Interleukin-6 9.248e-14 0.56
NOS2_RAT Nos2 Nitric oxide synthase, inducible 1.203e-13 0.30
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 1.227e-10 0.32
ANDR_RAT Ar Androgen receptor 9.546e-09 0.45
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.882e-08 0.33
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 4.877e-07 0.33
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.495e-06 0.42

Deserpidine

S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 1.228e-63 0.30
ADA2A_PIG ADRA2A Alpha-2A adrenergic receptor 5.692e-51 0.64
VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 1.036e-43 0.84
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 8.977e-33 0.84
GPVI_HUMAN GP6 Platelet glycoprotein VI 2.847e-23 0.29
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 4.388e-21 0.84
TRPM8_MOUSE Trpm8 Transient receptor potential cation channel subfamily M member 8 2.116e-20 0.36
Q25270_LEIDO beta-tubulin Beta-tubulin 3.757e-18 0.30
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.581e-17 0.64
TLR4_HUMAN TLR4 Toll-like receptor 4 4.387e-17 0.32
ACHA7_MOUSE Chrna7 Neuronal acetylcholine receptor subunit alpha-7 4.33e-15 0.31
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.144e-14 0.84
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 3.854e-13 0.64
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 5.148e-13 0.64
DRD1_HUMAN DRD1 D(1A) dopamine receptor 6.292e-13 0.34
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 1.117e-12 0.34
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 1.686e-12 0.64
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 5.561e-12 0.64
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 4.487e-11 0.30
SC6A3_BOVIN SLC6A3 Sodium-dependent dopamine transporter 7.648e-11 0.32
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 1.268e-09 0.33
DRD5_HUMAN DRD5 D(1B) dopamine receptor 4.629e-09 0.31
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 9.822e-09 0.84
NORA_STAAU norA Quinolone resistance protein NorA 1.262e-08 0.84
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 1.88e-08 0.30
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 4.368e-08 0.31
Q49PX0_9POXV N1L N1L 4.468e-08 0.28
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 5.897e-08 0.31
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 6.537e-08 0.64
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 1.003e-07 0.32
PDE5A_BOVIN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 1.163e-07 0.31
TF_HUMAN F3 Tissue factor 1.257e-07 0.33
AA2BR_RAT Adora2b Adenosine receptor A2b 2.725e-07 0.64
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 5.262e-07 0.49
PLD1_RAT Pld1 Phospholipase D1 8.498e-07 0.34
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 8.874e-07 0.64
MIP_LEGPN mip Outer membrane protein MIP 1.08e-06 0.28
PDE5A_HUMAN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 1.239e-06 0.32
KLK7_HUMAN KLK7 Kallikrein-7 2.783e-06 0.33
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 3.927e-06 0.35
ADA2B_RAT Adra2b Alpha-2B adrenergic receptor 4.267e-06 0.64
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 5.455e-06 0.30
P96830_MYCTO TYR_PHOSPHATASE_2 domain-containing protein 5.988e-06 0.30
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 9.349e-06 0.29

Amifostine

APAH_MYCRA aphA Acetylpolyamine amidohydrolase 2.935e-60 0.39
Q964Q8_TRYCR SPPS Solanesyl diphosphate synthase 8.345e-52 0.32
Q8WS26_TRYCR Farnesyl diphosphate synthase 3.581e-37 0.32
Q197X6_TOXGO FPPS Farnesyl diphosphate synthase 5.45e-35 0.32
GABR2_RAT Gabbr2 Gamma-aminobutyric acid type B receptor subunit 2 9.962e-27 0.34
DHYS_RAT Dhps Deoxyhypusine synthase 7.128e-24 0.39
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 6.732e-20 0.34
PAOX_HUMAN PAOX Peroxisomal N(1)-acetyl-spermine/spermidine oxidase 1.801e-13 0.40
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 3.26e-10 0.33
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 3.863e-09 0.33
TF65_HUMAN RELA Transcription factor p65 1.313e-07 0.30
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 2.078e-07 0.30
GBRR1_HUMAN GABRR1 Gamma-aminobutyric acid receptor subunit rho-1 3.553e-06 0.34
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 5.807e-06 0.32
PAO1_MAIZE MPAO1 Polyamine oxidase 1 6.636e-06 0.32

Trilostane

TAT_HV112 tat Protein Tat 1.552e-59 0.52
Q95MF8_PIG Sulfotransferase 8.646e-56 0.32
SHBG_HUMAN SHBG Sex hormone-binding globulin 4.354e-44 0.38
SHBG_RAT Shbg Sex hormone-binding globulin 1.275e-29 0.37
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 2.153e-26 0.38
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.956e-21 0.31
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 6.654e-21 0.33
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.369e-20 0.33
ANDR_RAT Ar Androgen receptor 1.11e-16 0.40
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.221e-15 0.35
CP19A_HUMAN CYP19A1 Aromatase 1.271e-13 0.42
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 2.315e-13 0.33
ESR2_HUMAN ESR2 Estrogen receptor beta 3.909e-13 0.37
Q690N0_BOVIN PGR Progesterone receptor 2.078e-12 0.37
ANDR_HUMAN AR Androgen receptor 1.877e-11 0.37
ESR1_MOUSE Esr1 Estrogen receptor 2.049e-10 0.33
ESR2_MOUSE Esr2 Estrogen receptor beta 2.049e-10 0.33
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 6.146e-10 0.30
ESR1_HUMAN ESR1 Estrogen receptor 3.086e-09 0.37
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 4.3e-07 0.33
ANDR_MOUSE Ar Androgen receptor 3.407e-06 0.37
MCR_RAT Nr3c2 Mineralocorticoid receptor 4.431e-06 0.37

Capecitabine

ADK_HUMAN ADK Adenosine kinase 1.547e-58 0.47
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 9.496e-54 0.43
NAAA_HUMAN NAAA N-acylethanolamine-hydrolyzing acid amidase 1.622e-52 0.35
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 4.756e-47 0.35
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 2.325e-39 0.34
POLG_POL1M Genome polyprotein 1.674e-38 0.30
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 8.648e-35 0.33
OXGR1_RAT Oxgr1 2-oxoglutarate receptor 1 7.235e-32 0.31
ASAH1_RAT Asah1 Acid ceramidase 7.951e-30 0.30
KITH_VZVO TK Thymidine kinase 1.208e-27 0.34
IF4E_MOUSE Eif4e Eukaryotic translation initiation factor 4E 1.282e-24 0.29
FTSZ_MYCTU ftsZ Cell division protein FtsZ 1.529e-23 0.29
ADA_MOUSE Ada Adenosine deaminase 4.185e-23 0.28
MRAY_BACSU mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase 2.576e-18 0.29
GSTM1_HUMAN GSTM1 Glutathione S-transferase Mu 1 3.72e-18 0.29
AA3R_RAT Adora3 Adenosine receptor A3 2.22e-16 0.32
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 1.998e-15 0.33
MBTA_MYCTU mbtA Salicyl-AMP ligase / salicyl-S-ArCP synthetase 5.218e-14 0.29
ENV_HV1H2 env Envelope glycoprotein gp160 3.922e-13 0.29
P2RY1_RAT P2ry1 P2Y purinoceptor 1 5.476e-13 0.28
AA1R_RAT Adora1 Adenosine receptor A1 1.629e-12 0.36
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 3.346e-11 0.31
AA2AR_RAT Adora2a Adenosine receptor A2a 3.93e-10 0.36
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 5.866e-10 0.29
RAB7A_HUMAN RAB7A Ras-related protein Rab-7a 2.343e-09 0.29
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 2.851e-09 0.29
RASK_HUMAN KRAS GTPase KRas 3.431e-09 0.28
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 4.536e-09 0.31
KITM_HUMAN TK2 Thymidine kinase 2, mitochondrial 3.37e-08 0.29
ASAH1_HUMAN ASAH1 Acid ceramidase 5.356e-07 0.30
CDD_MOUSE Cda Cytidine deaminase 5.464e-07 0.28
CDD_HUMAN CDA Cytidine deaminase 3.133e-06 0.28
ADK_RAT Adk Adenosine kinase 4.506e-06 0.33
P2RX1_RAT P2rx1 P2X purinoceptor 1 5.131e-06 0.31
GLCM_HUMAN GBA Lysosomal acid glucosylceramidase 6.008e-06 0.30
C3SIU2_ECOLX metJ Met repressor 7.607e-06 0.28

Chloroprocaine

AMYP_RAT Amy2 Pancreatic alpha-amylase 4.33e-58 0.41
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 5.349e-37 0.47
Q8WMX0_BOVIN Muscarinic receptor M1 7.911e-31 0.41
ERG1_RAT Sqle Squalene monooxygenase 7.217e-26 0.31
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 7.919e-26 0.47
ASIC1_HUMAN ASIC1 Acid-sensing ion channel 1 6.243e-24 0.29
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 2.056e-20 0.32
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 3.323e-20 0.34
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 7.238e-19 0.40
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 7.054e-18 0.40
Q9FYV8_MAIZE Protoporphyrinogen oxidase 2.334e-17 0.34
ERG2_YEAST ERG2 C-8 sterol isomerase 3.331e-16 0.34
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 5.551e-16 0.30
MBTP1_HUMAN MBTPS1 Membrane-bound transcription factor site-1 protease 6.661e-16 0.29
VATB1_HUMAN ATP6V1B1 V-type proton ATPase subunit B, kidney isoform 1.704e-13 0.29
VPP1_CHICK ATP6V0A1 V-type proton ATPase 116 kDa subunit a isoform 1 1.704e-13 0.29
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 2.811e-13 0.45
CDKA1_HUMAN CDK2AP1 Cyclin-dependent kinase 2-associated protein 1 2.182e-12 0.31
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 7.334e-12 0.29
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 4.943e-11 0.42
A3KMY8_BOVIN GUSB Beta-glucuronidase 2.864e-10 0.32
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.935e-09 0.33
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 3.514e-09 0.50
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.018e-08 0.40
B2LA1_MOUSE Bcl2a1 Bcl-2-related protein A1 2.43e-08 0.29
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 1.124e-07 0.31
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 2.026e-07 0.32
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 3.121e-07 0.39
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 3.829e-07 0.29
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 4.877e-07 0.50
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 7.351e-07 0.30
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 1.171e-06 0.36
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.793e-06 0.41
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 1.833e-06 0.32
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 6.433e-06 0.29
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 7.991e-06 0.30

Gliclazide

FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 1.184e-56 0.39
AMYP_PIG AMY2 Pancreatic alpha-amylase 2.166e-51 0.33
LN28A_MOUSE Lin28a Protein lin-28 homolog A 7.774e-43 0.34
FFAR4_RAT Ffar4 Free fatty acid receptor 4 1.822e-32 0.32
Q9TU16_CANLF PTGER4 Prostaglandin E receptor 4 9.393e-28 0.34
CPNS1_PIG CAPNS1 Calpain small subunit 1 6.367e-27 0.33
H9YX08_MACMU CCR6 C-C chemokine receptor type 6 9.218e-26 0.32
Q388H8_TRYB2 Glycylpeptide N-tetradecanoyltransferase 2.461e-25 0.34
Q26964_TRYCR TCTS-154 Trans-sialidase 6.731e-25 0.31
Q4Q5S8_LEIMA NMT Glycylpeptide N-tetradecanoyltransferase 4.332e-23 0.31
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 3.305e-17 0.41
MMP2_HUMAN MMP2 72 kDa type IV collagenase 1.11e-16 0.36
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.11e-16 0.38
NMT1_HUMAN NMT1 Glycylpeptide N-tetradecanoyltransferase 1 7.772e-16 0.31
KMO_RAT Kmo Kynurenine 3-monooxygenase 6.217e-15 0.32
CAH2_BOVIN CA2 Carbonic anhydrase 2 1.354e-14 0.36
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 4.174e-14 0.41
NMT_ASPFU nmt1 Glycylpeptide N-tetradecanoyltransferase 8.349e-14 0.30
ABCBB_RAT Abcb11 Bile salt export pump 9.681e-14 0.34
GSP_CRIFA GSP Glutathionylspermidine synthase 5.558e-13 0.32
TASP1_HUMAN TASP1 Threonine aspartase 1 7.039e-13 0.35
KCNQ1_HUMAN KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 2.931e-12 0.30
CAN1_RAT Capn1 Calpain-1 catalytic subunit 5.853e-12 0.32
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 6.625e-12 0.40
MMP13_HUMAN MMP13 Collagenase 3 3.789e-11 0.36
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 1.336e-10 0.28
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.246e-10 0.42
MMP1_HUMAN MMP1 Interstitial collagenase 3.395e-10 0.36
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 4.601e-10 0.38
ABCC8_HUMAN ABCC8 ATP-binding cassette sub-family C member 8 4.842e-10 0.34
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 4.876e-10 0.34
MMP7_HUMAN MMP7 Matrilysin 5.009e-10 0.36
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.187e-09 0.46
METC_ECOLI metC Cystathionine beta-lyase MetC 1.498e-09 0.38
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.694e-09 0.46
MCLN3_HUMAN MCOLN3 Mucolipin-3 2.947e-09 0.39
ITA4_HUMAN ITGA4 Integrin alpha-4 5.309e-09 0.36
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 5.51e-09 0.34
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 6.077e-09 0.32
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 1.156e-08 0.36
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 1.563e-08 0.37
MMP3_HUMAN MMP3 Stromelysin-1 2.007e-08 0.36
MMP26_HUMAN MMP26 Matrix metalloproteinase-26 4.372e-08 0.32
O39930_9HEPC NS5b RNA-directed RNA polymerase 6.583e-08 0.32
CAH9_HUMAN CA9 Carbonic anhydrase 9 7.365e-08 0.46
MMP8_HUMAN MMP8 Neutrophil collagenase 1.025e-07 0.36
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 2.569e-07 0.30
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 3.276e-07 0.36
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 4.821e-07 0.40
CAH12_HUMAN CA12 Carbonic anhydrase 12 5.853e-07 0.46
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 8.279e-07 0.31
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.507e-06 0.30
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 1.907e-06 0.32
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 1.907e-06 0.32
S12A5_HUMAN SLC12A5 Solute carrier family 12 member 5 1.963e-06 0.37
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 1.993e-06 0.34
STS_HUMAN STS Steryl-sulfatase 2.209e-06 0.33
HNF4A_RAT Hnf4a Hepatocyte nuclear factor 4-alpha 2.455e-06 0.35
RPGF4_HUMAN RAPGEF4 Rap guanine nucleotide exchange factor 4 3.555e-06 0.31
CAH4_BOVIN CA4 Carbonic anhydrase 4 4.348e-06 0.43
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 4.443e-06 0.34
HEPS_HUMAN HPN Serine protease hepsin 4.577e-06 0.30
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 4.68e-06 0.31
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 4.842e-06 0.30
TRY1_BOVIN Cationic trypsin 5.27e-06 0.31
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 5.385e-06 0.40
VIPR2_HUMAN VIPR2 Vasoactive intestinal polypeptide receptor 2 7.11e-06 0.31
COLA_CLOPE colA Collagenase ColA 7.347e-06 0.33

Vigabatrin

FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 4.369e-55 0.38
GBRT_HUMAN GABRQ Gamma-aminobutyric acid receptor subunit theta 5.166e-42 0.33
S6A13_RAT Slc6a13 Sodium- and chloride-dependent GABA transporter 2 5.166e-42 0.33
GRM8_MOUSE Grm8 Metabotropic glutamate receptor 8 1.921e-39 0.31
BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 1.814e-38 0.35
AAA1_RAT Slc7a10 Asc-type amino acid transporter 1 3.875e-36 0.29
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 4.231e-31 0.40
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 5.899e-31 0.46
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 7.011e-29 0.35
GGH_HUMAN GGH Gamma-glutamyl hydrolase 9.393e-28 0.34
GSTK1_HUMAN GSTK1 Glutathione S-transferase kappa 1 6.243e-24 0.29
GABT_PIG ABAT 4-aminobutyrate aminotransferase, mitochondrial 3.462e-20 0.32
GNPAT_HUMAN GNPAT Dihydroxyacetone phosphate acyltransferase 7.563e-20 0.32
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 3.122e-19 0.31
VGLU3_RAT Slc17a8 Vesicular glutamate transporter 3 9.056e-18 0.28
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 1.882e-17 0.33
BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 3.331e-16 0.37
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.221e-15 0.30
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 5.018e-14 0.32
Q9I056_PSEAE cpg2 Carboxypeptidase G2 7.55e-14 0.30
GLN1B_ECOLI glnA Glutamine synthetase 1.704e-13 0.29
GRM6_RAT Grm6 Metabotropic glutamate receptor 6 5.528e-12 0.31
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 2.335e-11 0.33
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.335e-11 0.33
Q6RY99_RAT Tetraspanin 4.757e-11 0.30
PA2GC_HUMAN PLA2G2C Putative inactive group IIC secretory phospholipase A2 1.517e-10 0.31
GRM8_RAT Grm8 Metabotropic glutamate receptor 8 4.123e-10 0.31
DDAH1_HUMAN DDAH1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 1.709e-08 0.30
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 4.403e-08 0.33
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 1.323e-07 0.34
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 2.554e-07 0.32
DCOR_RAT Odc1 Ornithine decarboxylase 2.994e-07 0.28
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 3.888e-07 0.32
Q6UB75_PIG Group VII phospholipase A2 4.905e-07 0.29
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 5.944e-07 0.33
GRIK2_HUMAN GRIK2 Glutamate receptor ionotropic, kainate 2 6.637e-07 0.32
GRIK2_RAT Grik2 Glutamate receptor ionotropic, kainate 2 8.358e-07 0.30
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 8.358e-07 0.30
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 9.875e-07 0.33
GRM8_HUMAN GRM8 Metabotropic glutamate receptor 8 1.166e-06 0.34
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 1.643e-06 0.34
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 1.923e-06 0.32
GBRR1_HUMAN GABRR1 Gamma-aminobutyric acid receptor subunit rho-1 5.201e-06 0.33
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 5.237e-06 0.31
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 6.801e-06 0.30

Amdinocillin

BLAB_BACCE Metallo-beta-lactamase type 2 4.859e-55 0.48
D5HSX5_9GAMM blaPER-6 Beta-lactamase 1.841e-40 0.32
Q0VTR6_ACIPI adc-14 Beta-lactamase 1.841e-40 0.32
Q0VTR8_ACIPI adc-16 Beta-lactamase 1.841e-40 0.32
Q7X575_ECOLX SHV-11 Beta-lactamase 1.841e-40 0.32
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 2.83e-30 0.38
A1E3K9_ECOLX blaSCO-1 Beta-lactamase 5.085e-26 0.32
A8RR46_BACCS bcl1 Beta-lactamase 5.085e-26 0.32
D2SSQ3_PSEAI Beta-lactamase 5.085e-26 0.32
Q3SAW3_PSEAI bla(BEL1) Beta-lactamase 5.085e-26 0.32
Q3S5C3_SALNE sugE Efflux transporter 2.07e-23 0.38
Q48435_KLEPN bla LAT-2 Beta-lactamase 2.07e-23 0.38
D1MIX9_PSEAI blaGES-13 Beta-lactamase 3.801e-20 0.32
AMPC_ECOLI ampC Beta-lactamase 5.388e-20 0.52
A2RP81_CITFR blaPER-2 Beta-lactamase 1.11e-16 0.37
BLAT_ECOLX bla; blaT-3; blaT-4; blaT-5; blaT-6 Beta-lactamase TEM 7.661e-15 0.33
AMPC_ENTCL ampC Beta-lactamase 1.334e-13 0.36
BLA1_STEMA Metallo-beta-lactamase L1 type 3 7.561e-10 0.31
BLAC_STAAU blaZ Beta-lactamase 5.886e-09 0.32
BLAB_BACFG ccrA Metallo-beta-lactamase type 2 3.209e-08 0.30

Streptomycin

AMYP_HUMAN AMY2A Pancreatic alpha-amylase 5.433e-55 0.33
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 2.417e-52 0.36
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 5.879e-29 0.28
CHIT_YEAST CTS1 Endochitinase 1.208e-27 0.34
MAG_HUMAN MAG Myelin-associated glycoprotein 4.796e-23 0.32
LEG4_HUMAN LGALS4 Galectin-4 3.983e-19 0.30
LEG8_HUMAN LGALS8 Galectin-8 3.983e-19 0.30
FGF1_HUMAN FGF1 Fibroblast growth factor 1 2.22e-16 0.29
CD69_HUMAN CD69 Early activation antigen CD69 6.661e-16 0.39
AMY1A_HUMAN AMY1A Alpha-amylase 1 8.882e-16 0.30
P94451_GEOSE Alpha-amylase 9.504e-14 0.30
LEG3_HUMAN LGALS3 Galectin-3 1.99e-13 0.31
FGF2_HUMAN FGF2 Fibroblast growth factor 2 3.029e-13 0.29
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 9.639e-10 0.29
LEG7_HUMAN LGALS7; LGALS7B Galectin-7 7.799e-08 0.29
LEF_BACAN lef Lethal factor 4.362e-07 0.40
CHIA_HUMAN CHIA Acidic mammalian chitinase 1.763e-06 0.34
SUIS_HUMAN SI Sucrase-isomaltase, intestinal 3.897e-06 0.28
CHIB_SERMA chiB Chitinase B 5.491e-06 0.34

Sulfinpyrazone

MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 3.786e-54 0.44
MURB_STAAU murB UDP-N-acetylenolpyruvoylglucosamine reductase 1.252e-44 0.43
MURA_ECOLI murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2.202e-25 0.42
LOXL4_HUMAN LOXL4 Lysyl oxidase homolog 4 3.109e-15 0.29
LOXL3_HUMAN LOXL3 Lysyl oxidase homolog 3 3.301e-08 0.29
LYOX_HUMAN LOX Protein-lysine 6-oxidase 6.235e-06 0.29

Atovaquone

Q9MYJ9_RABIT CCR1 Chemokine receptor 2.422e-46 0.37
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 4.071e-39 0.37
TBA_TRYCR Tubulin alpha chain 3.98e-36 0.30
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 5.481e-22 0.35
ACHA9_RAT Chrna9 Neuronal acetylcholine receptor subunit alpha-9 4.368e-18 0.30
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 2.22e-15 0.35
CBPB_HELZE CPB Carboxypeptidase B 1.884e-13 0.29
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 2.067e-12 0.34
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 1.075e-11 0.34
TAAR1_RAT Taar1 Trace amine-associated receptor 1 1.266e-10 0.35
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 9.443e-10 0.36
Q9WTR4_RAT Slc6a2 Transporter 2.336e-09 0.33
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 3.259e-09 0.35
BIRC5_HUMAN BIRC5 Baculoviral IAP repeat-containing protein 5 1.292e-08 0.29
HKDC1_HUMAN HKDC1 Hexokinase HKDC1 2.355e-08 0.33
SQHC_ALIAD shc Squalene--hopene cyclase 2.835e-08 0.30
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 5.519e-08 0.30
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 8.153e-08 0.33
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 8.23e-08 0.31
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 1.526e-07 0.35
EST2_HUMAN CES2 Cocaine esterase 9.025e-07 0.33
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 1.056e-06 0.35
SC6A4_MACMU SLC6A4 Sodium-dependent serotonin transporter 1.137e-06 0.28
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 2.011e-06 0.33
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.049e-06 0.29
EST1_HUMAN CES1 Liver carboxylesterase 1 2.327e-06 0.33
V1AR_MOUSE Avpr1a Vasopressin V1a receptor 2.488e-06 0.30
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 2.845e-06 0.30
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 2.989e-06 0.32
KPCZ_HUMAN PRKCZ Protein kinase C zeta type 4.125e-06 0.33
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 5.084e-06 0.32
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 5.416e-06 0.35

Amoxicillin

S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 1.313e-42 0.53
BLAB_BACCE Metallo-beta-lactamase type 2 9.34e-38 0.43
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 3.04e-35 0.44
Q3S5C3_SALNE sugE Efflux transporter 3.19e-27 0.44
Q48435_KLEPN bla LAT-2 Beta-lactamase 3.19e-27 0.44
A2RP81_CITFR blaPER-2 Beta-lactamase 5.55e-23 0.51
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 5.295e-17 0.32
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 2.331e-15 0.53
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.225e-12 0.53
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 3.72e-12 0.31
AMPC_ECOLI ampC Beta-lactamase 6.333e-12 0.49
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 1.508e-10 0.28
Q82134_9DELA prt Protease 2.07e-10 0.29
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 1.19e-09 0.30
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 2.702e-09 0.32
OPRD_MOUSE Oprd1 Delta-type opioid receptor 6.008e-09 0.31
OPRD_RAT Oprd1 Delta-type opioid receptor 1.454e-07 0.32
OPRM_CAVPO OPRM1 Mu-type opioid receptor 4.471e-07 0.31
OPRX_CAVPO OPRL1 Nociceptin receptor 3.531e-06 0.28
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 3.608e-06 0.30

Sulfoxone

FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.625e-41 0.34
O77078_PLAFA fabH Beta-ketoacyl-acyl carrier protein synthase III 5.318e-41 0.32
Q5VLE3_EMEND rmtA RmtA 1.306e-22 0.36
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 1.213e-17 0.37
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 5.295e-17 0.32
QCR7_HUMAN UQCRB Cytochrome b-c1 complex subunit 7 3.331e-16 0.31
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 9.992e-16 0.37
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.332e-15 0.33
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 3.775e-15 0.31
CYNT_HELPY cynT Carbonic anhydrase 9.703e-14 0.33
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.372e-11 0.38
CAH1_HUMAN CA1 Carbonic anhydrase 1 2.115e-09 0.38
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.16e-09 0.38
CAH9_HUMAN CA9 Carbonic anhydrase 9 4.374e-09 0.38
CAH4_BOVIN CA4 Carbonic anhydrase 4 8.05e-09 0.33
CAH14_HUMAN CA14 Carbonic anhydrase 14 3.013e-08 0.33
DDIT3_HUMAN DDIT3 DNA damage-inducible transcript 3 protein 6.213e-08 0.33
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 1.87e-07 0.44
CAH7_HUMAN CA7 Carbonic anhydrase 7 5.697e-07 0.33
Q6FTL6_CANGA NCE103 Carbonic anhydrase 8.092e-07 0.32
CAH_METTE Carbonic anhydrase 2.175e-06 0.31
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 2.442e-06 0.33

Rabeprazole

ENASE_HUMAN ENGASE Cytosolic endo-beta-N-acetylglucosaminidase 5.914e-39 0.63
ALKB3_HUMAN ALKBH3 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 3.309e-11 0.30
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 8.404e-06 0.28

Clonazepam

NCLX_HUMAN SLC8B1 Mitochondrial sodium/calcium exchanger protein 1.071e-38 0.31
NCAP_I33A0 NP Nucleoprotein 1.42e-25 0.32
S27A2_HUMAN SLC27A2 Very long-chain acyl-CoA synthetase 1.685e-24 0.30
SYUA_HUMAN SNCA Alpha-synuclein 2.457e-21 0.40
PGH1_RABIT PTGS1 Prostaglandin G/H synthase 1 2.788e-21 0.35
PGH2_RABIT PTGS2 Prostaglandin G/H synthase 2 6.551e-20 0.35
CCG8_HUMAN CACNG8 Voltage-dependent calcium channel gamma-8 subunit 3.331e-15 0.29
HPPD_RAT Hpd 4-hydroxyphenylpyruvate dioxygenase 1.01e-14 0.32
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 3.642e-14 0.41
TAU_HUMAN MAPT Microtubule-associated protein tau 1.849e-13 0.37
TSSK2_HUMAN TSSK2 Testis-specific serine/threonine-protein kinase 2 1.364e-12 0.43
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 1.545e-12 0.37
I23O2_HUMAN IDO2 Indoleamine 2,3-dioxygenase 2 8.819e-12 0.32
CASP4_HUMAN CASP4 Caspase-4 6.665e-11 0.36
TRXR2_PLAF7 trxr2 Thioredoxin reductase 2 1.369e-10 0.28
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 1.667e-10 0.48
TAT_HV112 tat Protein Tat 2.873e-10 0.47
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 4.569e-10 0.29
CASP9_HUMAN CASP9 Caspase-9 6.539e-10 0.36
H9B8T9_CAPHI CTSB Cathepsin B 1.379e-09 0.30
A0A060INS8_CAPHI CTSH Cathepsin H 3.825e-09 0.30
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 1.563e-08 0.43
OXDA_PIG DAO D-amino-acid oxidase 2.026e-08 0.30
KPCG_RAT Prkcg Protein kinase C gamma type 5.758e-08 0.32
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 1.199e-07 0.28
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.393e-07 0.41
CAH11_HUMAN CA11 Carbonic anhydrase-related protein 11 2.22e-07 0.30
FABI_BACSU fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 2.38e-07 0.30
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 1.244e-06 0.28
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 2.859e-06 0.31
CCNE1_HUMAN CCNE1 G1/S-specific cyclin-E1 7.718e-06 0.38
Q8MWR1_SPOFR USP Ultraspiracle protein 8.152e-06 0.29
Q8MWR2_SPOFR EcR Ecdysteroid receptor 8.152e-06 0.29

Proguanil

SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.275e-38 0.50
Q76270_9HIV1 HIV1 ENV GP41 6.694e-38 0.30
O69638_MYCTO Hydrolase, alpha/beta hydrolase fold family 9.362e-36 0.28
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 8.709e-24 0.33
FFAR2_HUMAN FFAR2 Free fatty acid receptor 2 4.755e-23 0.32
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 7.097e-22 0.41
PSBA_MARPO psbA Photosystem II protein D1 1.878e-21 0.39
EPHB_MYCTO Epoxide hydrolase B 2.157e-21 0.34
S100B_HUMAN S100B Protein S100-B 6.412e-19 0.29
PSBA_SPIOL psbA Photosystem II protein D1 1.11e-16 0.39
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.11e-16 0.33
PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 8.882e-16 0.33
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 9.548e-15 0.33
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 1.154e-13 0.39
H9CNL0_SPOEX Ryanodien receptor 1.647e-10 0.28
GBRA1_RAT Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 1.991e-10 0.35
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 2.351e-10 0.33
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 2.69e-10 0.45
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 3.073e-10 0.35
Q6DMN0_TOXGO CPL Cathepsin L 5.162e-10 0.29
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 7.415e-10 0.35
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 7.957e-10 0.45
GBRG2_RAT Gabrg2 Gamma-aminobutyric acid receptor subunit gamma-2 1.729e-09 0.35
PYRD_RAT Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 2.126e-09 0.33
TAAR1_RAT Taar1 Trace amine-associated receptor 1 4.512e-09 0.36
UR2R_HUMAN UTS2R Urotensin-2 receptor 1.514e-08 0.33
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 2.303e-08 0.40
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 4.269e-08 0.34
LIPL_RAT Lpl Lipoprotein lipase 5.111e-08 0.30
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 6.354e-08 0.33
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 7.803e-08 0.55
FFAR2_MOUSE Ffar2 Free fatty acid receptor 2 8.839e-08 0.29
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 1.31e-07 0.34
ACRO_HUMAN ACR Acrosin 3.024e-07 0.34
Q6FTL6_CANGA NCE103 Carbonic anhydrase 3.083e-07 0.33
AMPN_PIG ANPEP Aminopeptidase N 3.253e-07 0.32
FA11_HUMAN F11 Coagulation factor XI 3.304e-07 0.31
Q25615_ONCVO Chitinase 3.706e-07 0.29
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 5.622e-07 0.28
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 1.433e-06 0.45
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 2.252e-06 0.30
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.521e-06 0.29
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 3.572e-06 0.30
CAN1_RAT Capn1 Calpain-1 catalytic subunit 5.734e-06 0.29
Q03732_HBV HBcAg Capsid protein 7.679e-06 0.30
PAO1_MAIZE MPAO1 Polyamine oxidase 1 8.307e-06 0.31

Colistimethate

O07911_STAAU agrC AgrC 1.529e-32 0.33
ADAM8_HUMAN ADAM8 Disintegrin and metalloproteinase domain-containing protein 8 8.425e-19 0.30
AGRA_STAAU agrA Accessory gene regulator protein A 2.566e-12 0.30
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 4.397e-12 0.33
DLG4_HUMAN DLG4 Disks large homolog 4 1.324e-11 0.29
P96830_MYCTO TYR_PHOSPHATASE_2 domain-containing protein 4.194e-11 0.30
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 7.26e-07 0.29
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 7.619e-07 0.28

Bretylium

ACHB_TETCF CHRNB1 Acetylcholine receptor subunit beta 1.604e-19 0.34
ACHG_TETCF CHRNG Acetylcholine receptor subunit gamma 1.604e-19 0.34
ACHD_TETCF chrnd Acetylcholine receptor subunit delta 2.107e-17 0.34
CP27A_HUMAN CYP27A1 Sterol 26-hydroxylase, mitochondrial 2.986e-13 0.29
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 2.919e-12 0.34
DYR_MYCTU folA Dihydrofolate reductase 7.71e-12 0.32

Pentolinium

BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 2.3e-09 0.56
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 6.072e-07 0.31

Flucytosine

OXDA_RAT Dao D-amino-acid oxidase 1.623e-08 0.36
OXDA_PIG DAO D-amino-acid oxidase 1.3e-06 0.36

Oxamniquine

A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 2.423e-07 0.31
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 1.692e-06 0.30