Results of Job: search_e05954f7-6aec-45cd-bae2-4c314d22dd2a

Query Target Key Target Name Description P-Value MaxTC

compound_1

DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 7.32e-82 0.69
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 5.577e-78 0.64
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 3.488e-68 0.67
SIA4B_RAT St3gal2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 5.061e-68 0.36
CP11A_BOVIN CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial 2.581e-66 0.53
EPHA2_MOUSE Epha2 Ephrin type-A receptor 2 1.069e-63 0.38
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 3.524e-63 0.53
CRYAB_HUMAN CRYAB Alpha-crystallin B chain 1.473e-53 0.67
DHCR7_RAT Dhcr7 7-dehydrocholesterol reductase 4.876e-53 0.69
CP125_MYCTU cyp125 Steroid C26-monooxygenase 9.526e-53 0.66
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 9.252e-42 0.36
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 1.526e-38 0.47
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 1.666e-38 0.32
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 2.87e-38 0.46
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 5.761e-37 0.46
SMT1_ARATH SMT1 Cycloartenol-C-24-methyltransferase 1.36e-35 0.58
CDC45_HUMAN CDC45 Cell division control protein 45 homolog 1.71e-35 0.28
CP17A_MACFA CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.527e-33 0.42
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.776e-33 0.53
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 6.203e-33 0.36
SHBG_HUMAN SHBG Sex hormone-binding globulin 3.702e-31 0.52
VDR_RAT Vdr Vitamin D3 receptor 6.288e-29 0.33
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 1.772e-28 0.36
NTCP2_HUMAN SLC10A2 Ileal sodium/bile acid cotransporter 5.434e-27 0.36
FGF2_HUMAN FGF2 Fibroblast growth factor 2 5.679e-26 0.57
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 3.091e-24 0.52
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 3.553e-24 0.75
CD4_HUMAN CD4 T-cell surface glycoprotein CD4 4.51e-24 0.30
CAH4_BOVIN CA4 Carbonic anhydrase 4 2.253e-23 0.35
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.179e-22 0.43
ERG2_YEAST ERG2 C-8 sterol isomerase 2.141e-22 0.49
NR1H4_HUMAN NR1H4 Bile acid receptor 1.087e-18 0.39
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 8.104e-18 0.28
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 1.11e-16 0.34
SHH_HUMAN SHH Sonic hedgehog protein 1.221e-15 0.40
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 2.22e-15 0.52
ESR2_HUMAN ESR2 Estrogen receptor beta 2.442e-15 0.46
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 4.552e-15 0.51
RORA_HUMAN RORA Nuclear receptor ROR-alpha 1.921e-14 0.49
ANDR_HUMAN AR Androgen receptor 3.153e-14 0.46
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 9.481e-14 0.67
REST_BORBU resT Telomere resolvase ResT 9.837e-14 0.34
ABCBB_HUMAN ABCB11 Bile salt export pump 1.014e-13 0.34
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2.084e-12 0.49
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 2.098e-12 0.51
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 3.897e-12 0.51
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 1.218e-11 0.51
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 1.218e-11 0.51
ESR1_HUMAN ESR1 Estrogen receptor 3.336e-11 0.46
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 3.394e-11 0.51
GLI1_HUMAN GLI1 Zinc finger protein GLI1 6.11e-11 0.40
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 1.322e-10 0.51
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 1.322e-10 0.51
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 1.998e-10 0.51
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 2.966e-10 0.51
VDR_HUMAN VDR Vitamin D3 receptor 5.424e-10 0.39
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 1.305e-09 0.54
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 1.7e-09 0.51
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.098e-08 0.35
FGF1_HUMAN FGF1 Fibroblast growth factor 1 1.201e-08 0.29
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 1.528e-08 0.51
ECR_DROME EcR Ecdysone receptor 1.656e-08 0.29
CAH2_HUMAN CA2 Carbonic anhydrase 2 2.082e-08 0.35
ANDR_RAT Ar Androgen receptor 2.388e-08 0.32
DPOLB_RAT Polb DNA polymerase beta 5.466e-08 0.39
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 9.841e-08 0.31
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.796e-07 0.31
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.869e-07 0.28
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 4.123e-07 0.75
IL2_HUMAN IL2 Interleukin-2 5.919e-07 0.37
HRH3_RAT Hrh3 Histamine H3 receptor 1.332e-06 0.34
CP19A_HUMAN CYP19A1 Aromatase 1.505e-06 0.53
RORG_HUMAN RORC Nuclear receptor ROR-gamma 1.767e-06 0.70
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 7.537e-06 0.28
GBA2_HUMAN GBA2 Non-lysosomal glucosylceramidase 7.807e-06 0.48