Results of Job: search_e5c10261-8aa6-4759-a5c8-95058a712735

Query Target Key Target Name Description P-Value MaxTC

compound_1

BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 5.312e-157 0.51
AURKA_HUMAN AURKA Aurora kinase A 1.624e-117 0.49
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 5.78e-116 0.49
TPOR_HUMAN MPL Thrombopoietin receptor 7.128e-102 0.45
A1Z199_HUMAN BCR/ABL fusion BCR/ABL p210 fusion protein 1.576e-98 0.34
EGFR_HUMAN EGFR Epidermal growth factor receptor 5.779e-89 0.44
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 1.001e-79 0.35
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 6.289e-75 0.43
AURKB_HUMAN AURKB Aurora kinase B 8.829e-72 0.46
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.066e-70 0.38
SHH_MOUSE Shh Sonic hedgehog protein 2.429e-69 0.39
CTNB1_HUMAN CTNNB1 Catenin beta-1 4.251e-69 0.43
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 3.732e-64 0.44
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 2.379e-63 0.36
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 9.894e-61 0.41
TMPS4_HUMAN TMPRSS4 Transmembrane protease serine 4 1.738e-52 0.36
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 8.489e-52 0.42
RXFP1_HUMAN RXFP1 Relaxin receptor 1 2.068e-49 0.35
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 3.64e-49 0.41
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 1.754e-48 0.44
APOB_HUMAN APOB Apolipoprotein B-100 2.21e-47 0.31
DUS2L_HUMAN DUS2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like 3.537e-46 0.37
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 4.833e-46 0.37
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 1.987e-45 0.32
LCK_HUMAN LCK Tyrosine-protein kinase Lck 3.117e-45 0.39
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 9.027e-44 0.36
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 8.342e-42 0.36
C3SLB7_ECOLX glmU Bifunctional protein GlmU 2.768e-39 0.43
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 4.695e-39 0.41
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 1.104e-37 0.34
AURKB_MOUSE Aurkb Aurora kinase B 1.317e-37 0.30
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.828e-37 0.41
ARAF_HUMAN ARAF Serine/threonine-protein kinase A-Raf 4.331e-35 0.38
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 1.324e-34 0.43
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 4.858e-34 0.36
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 2.669e-31 0.31
TIE2_HUMAN TEK Angiopoietin-1 receptor 7.989e-31 0.40
VGFR2_DANRE kdr Vascular endothelial growth factor receptor 2 1.089e-30 0.30
HSPB1_HUMAN HSPB1 Heat shock protein beta-1 1.268e-30 0.29
HCK_HUMAN HCK Tyrosine-protein kinase HCK 3.28e-30 0.36
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 1.247e-29 0.44
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 2.584e-28 0.43
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 8.106e-27 0.35
CD38_MOUSE Cd38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 1.787e-26 0.43
NR2C2_HUMAN NR2C2 Nuclear receptor subfamily 2 group C member 2 1.863e-26 0.33
AURKA_MOUSE Aurka Aurora kinase A 5.874e-26 0.30
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.671e-25 0.36
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 8.426e-25 0.34
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 3.955e-24 0.32
PTGES_CANLF PTGES Prostaglandin E synthase 8.092e-24 0.37
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 2.713e-22 0.38
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 6.634e-22 0.42
AUKBA_XENLA aurkb-a Aurora kinase B-A 1.353e-21 0.34
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 2.053e-21 0.34
BTK_HUMAN BTK Tyrosine-protein kinase BTK 2.27e-21 0.41
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 2.852e-21 0.41
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 3.414e-21 0.37
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 7.018e-21 0.30
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 7.297e-21 0.32
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 7.335e-21 0.38
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 1.629e-20 0.38
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 9.33e-20 0.32
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 3.023e-19 0.47
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 4.466e-19 0.38
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 5.207e-19 0.32
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 5.576e-19 0.30
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 6.81e-19 0.37
TEC_HUMAN TEC Tyrosine-protein kinase Tec 9.195e-19 0.33
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 9.247e-19 0.29
PTGES_HUMAN PTGES Prostaglandin E synthase 1.066e-18 0.41
HGFL_HUMAN MST1 Hepatocyte growth factor-like protein 1.126e-18 0.30
PRIO_SHEEP PRNP Major prion protein 1.287e-18 0.33
INSR_HUMAN INSR Insulin receptor 1.424e-18 0.36
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 2.026e-18 0.48
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 3.535e-18 0.48
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 1.099e-17 0.33
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 1.356e-17 0.30
LDLR_HUMAN LDLR Low-density lipoprotein receptor 1.918e-17 0.29
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 2.622e-17 0.31
SMO_MOUSE Smo Smoothened homolog 1.11e-16 0.32
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 1.11e-16 0.30
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 2.22e-16 0.31
BLK_HUMAN BLK Tyrosine-protein kinase Blk 1.665e-15 0.35
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 2.665e-15 0.33
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 2.998e-15 0.37
SMO_HUMAN SMO Smoothened homolog 2.998e-15 0.32
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 5.218e-15 0.33
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 6.217e-15 0.38
KCNQ2_RAT Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 8.993e-15 0.33
TNR16_HUMAN NGFR Tumor necrosis factor receptor superfamily member 16 1.987e-14 0.32
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 2.054e-14 0.32
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 2.287e-14 0.35
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 2.298e-14 0.30
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 2.454e-14 0.32
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 2.565e-14 0.42
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 6.395e-14 0.36
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 1.081e-13 0.30
TXK_HUMAN TXK Tyrosine-protein kinase TXK 1.124e-13 0.33
SCAF_HCMVA UL80 Capsid scaffolding protein 1.57e-13 0.33
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 1.854e-13 0.37
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 2.081e-13 0.35
EGFR_MOUSE Egfr Epidermal growth factor receptor 2.151e-13 0.29
TAAR1_RAT Taar1 Trace amine-associated receptor 1 3.59e-13 0.33
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 5.094e-13 0.42
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 5.372e-13 0.30
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 1.029e-12 0.30
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 1.101e-12 0.32
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 2.459e-12 0.32
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 2.971e-12 0.30
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 3.091e-12 0.30
ANDR_RAT Ar Androgen receptor 4.041e-12 0.37
GRM1_HUMAN GRM1 Metabotropic glutamate receptor 1 6.098e-12 0.38
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 6.96e-12 0.30
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 7.304e-12 0.31
WRN_HUMAN WRN Werner syndrome ATP-dependent helicase 8.473e-12 0.35
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 1.534e-11 0.33
CTRO_HUMAN CIT Citron Rho-interacting kinase 1.726e-11 0.30
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 2.543e-11 0.37
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 3.436e-11 0.33
HDAC3_HUMAN HDAC3 Histone deacetylase 3 3.642e-11 0.42
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 1.021e-10 0.33
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 1.248e-10 0.33
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 1.675e-10 0.28
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 1.837e-10 0.32
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 1.857e-10 0.30
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 1.99e-10 0.34
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 2.116e-10 0.30
FRK_HUMAN FRK Tyrosine-protein kinase FRK 2.477e-10 0.38
C11B2_MOUSE Cyp11b2 Cytochrome P450 11B2, mitochondrial 3.76e-10 0.29
CML1_HUMAN CMKLR1 Chemokine-like receptor 1 5.114e-10 0.38
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 6.332e-10 0.30
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 8.355e-10 0.33
CDKL3_HUMAN CDKL3 Cyclin-dependent kinase-like 3 8.577e-10 0.28
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 1.027e-09 0.30
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 1.26e-09 0.32
SUCR1_HUMAN SUCNR1 Succinate receptor 1 1.706e-09 0.30
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 1.751e-09 0.38
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 1.855e-09 0.30
NR1H4_HUMAN NR1H4 Bile acid receptor 2.023e-09 0.36
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 2.87e-09 0.30
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 3.008e-09 0.30
MCR_RAT Nr3c2 Mineralocorticoid receptor 3.341e-09 0.30
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 3.632e-09 0.38
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 4.654e-09 0.38
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 5.825e-09 0.30
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 6.361e-09 0.35
HDAC4_HUMAN HDAC4 Histone deacetylase 4 1.052e-08 0.34
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 1.23e-08 0.33
LIMK1_RAT Limk1 LIM domain kinase 1 1.464e-08 0.28
SIK1_HUMAN SIK1 Serine/threonine-protein kinase SIK1 1.622e-08 0.30
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 1.763e-08 0.33
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 1.866e-08 0.30
MK11_HUMAN MAPK11 Mitogen-activated protein kinase 11 2.048e-08 0.32
HDAC6_HUMAN HDAC6 Histone deacetylase 6 2.46e-08 0.34
KCJ11_HUMAN KCNJ11 ATP-sensitive inward rectifier potassium channel 11 2.602e-08 0.31
ST17A_HUMAN STK17A Serine/threonine-protein kinase 17A 2.625e-08 0.30
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 2.653e-08 0.30
TAOK2_HUMAN TAOK2 Serine/threonine-protein kinase TAO2 2.853e-08 0.30
A5H660_SCHMA HDAC8 Histone deacetylase 8 2.876e-08 0.32
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 2.885e-08 0.30
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 3.8e-08 0.32
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 4.164e-08 0.38
YES_HUMAN YES1 Tyrosine-protein kinase Yes 4.937e-08 0.33
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 4.982e-08 0.30
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 5.231e-08 0.33
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 6.3e-08 0.31
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 6.528e-08 0.35
TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 6.756e-08 0.30
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 8.754e-08 0.38
IL6_HUMAN IL6 Interleukin-6 9.613e-08 0.30
NLK_HUMAN NLK Serine/threonine-protein kinase NLK 1.041e-07 0.29
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 1.185e-07 0.30
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 1.24e-07 0.32
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 1.451e-07 0.30
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.487e-07 0.42
CDK3_HUMAN CDK3 Cyclin-dependent kinase 3 1.799e-07 0.29
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 1.894e-07 0.30
WNT3A_MOUSE Wnt3a Protein Wnt-3a 1.934e-07 0.29
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 2.542e-07 0.30
MYO3B_HUMAN MYO3B Myosin-IIIb 2.594e-07 0.28
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 3.085e-07 0.32
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 3.596e-07 0.34
CSK_HUMAN CSK Tyrosine-protein kinase CSK 3.695e-07 0.30
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 4.086e-07 0.32
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 4.163e-07 0.34
LIMK1_HUMAN LIMK1 LIM domain kinase 1 4.545e-07 0.34
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 4.669e-07 0.36
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 4.708e-07 0.38
SORT_HUMAN SORT1 Sortilin 5.023e-07 0.29
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 6.32e-07 0.34
SCNAA_HUMAN SCN10A Sodium channel protein type 10 subunit alpha 9.388e-07 0.30
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 1.186e-06 0.34
AOFB_RAT Maob Amine oxidase [flavin-containing] B 1.724e-06 0.33
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 1.827e-06 0.28
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 1.834e-06 0.36
BACE1_HUMAN BACE1 Beta-secretase 1 2.003e-06 0.32
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.028e-06 0.29
SENP7_HUMAN SENP7 Sentrin-specific protease 7 2.051e-06 0.32
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 2.233e-06 0.38
AURKC_HUMAN AURKC Aurora kinase C 2.239e-06 0.30
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 2.387e-06 0.33
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 2.538e-06 0.31
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 2.631e-06 0.30
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 3.011e-06 0.31
BLM_HUMAN BLM Bloom syndrome protein 3.129e-06 0.35
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 3.266e-06 0.30
E2AK4_HUMAN EIF2AK4 eIF-2-alpha kinase GCN2 3.295e-06 0.30
KCNQ3_HUMAN KCNQ3 Potassium voltage-gated channel subfamily KQT member 3 3.596e-06 0.33
DYRK3_HUMAN DYRK3 Dual specificity tyrosine-phosphorylation-regulated kinase 3 3.713e-06 0.31
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 4.259e-06 0.34
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 4.345e-06 0.34
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 4.45e-06 0.35
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 4.523e-06 0.30
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 5.463e-06 0.28
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 5.819e-06 0.32
Q76129_9HIV1 gag Structural capsid protein 6.129e-06 0.29
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 6.25e-06 0.31
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 6.315e-06 0.32
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 7.329e-06 0.30
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 7.652e-06 0.28
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 8.214e-06 0.32
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 8.363e-06 0.32
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 8.511e-06 0.38
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 8.931e-06 0.34
O97467_PLAFA ht1 Hexose transporter 1 9.114e-06 0.36