Results of Job: search_eadd48f6-fe63-4020-b5f5-991265a4b4be

Query Target Key Target Name Description P-Value MaxTC

Pitolisant

HRH3_HUMAN HRH3 Histamine H3 receptor 1.976e-156 1.00
HRH3_CAVPO HRH3 Histamine H3 receptor 1.055e-67 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 1.382e-53 1.00
HRH3_RAT Hrh3 Histamine H3 receptor 5.462e-52 1.00
HRH3_MOUSE Hrh3 Histamine H3 receptor 7.829e-52 1.00
HNMT_RAT Hnmt Histamine N-methyltransferase 5.667e-103 0.46
DRD4_RAT Drd4 D(4) dopamine receptor 4.858e-70 0.49
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.779e-65 0.53
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.678e-63 0.50
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 6.068e-57 0.40
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 9.768e-49 0.51
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 8.963e-45 0.53
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 2.009e-40 0.51
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 6.131e-39 0.42
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 1.538e-38 0.40
O19067_PIG N-methyl-D-aspartate receptor 2.427e-38 0.30
DRD5_HUMAN DRD5 D(1B) dopamine receptor 1.594e-36 0.47
TYTR_TRYBB TPR Trypanothione reductase 2.232e-33 0.33
LMBL3_HUMAN L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 3.507e-31 0.47
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.321e-29 0.47
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 5.076e-28 0.43
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 8.468e-28 0.40
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 9.201e-28 0.39
NPY1R_RAT Npy1r Neuropeptide Y receptor type 1 2.325e-27 0.34
ACES_ELEEL ache Acetylcholinesterase 4.665e-27 0.41
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 6.351e-27 0.47
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.296e-26 0.38
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 1.246e-25 0.32
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 1.406e-25 0.42
MURB_STAAU murB UDP-N-acetylenolpyruvoylglucosamine reductase 4.152e-25 0.33
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 7.854e-25 0.31
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 8.969e-25 0.38
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 1.939e-24 0.40
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.773e-24 0.49
DRD2_MOUSE Drd2 D(2) dopamine receptor 5.132e-24 0.40
ZN664_CAVPO ZNF664 Zinc finger protein 664 1.839e-23 0.29
FA8_HUMAN F8 Coagulation factor VIII 1.926e-23 0.29
DRD4_HUMAN DRD4 D(4) dopamine receptor 2.289e-23 0.40
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 1.889e-22 0.34
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 2.628e-22 0.35
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 2.848e-22 0.50
NORA_STAAU norA Quinolone resistance protein NorA 4.329e-22 0.36
DRD3_HUMAN DRD3 D(3) dopamine receptor 4.127e-21 0.49
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 4.663e-21 0.37
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 5.394e-21 0.47
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.048e-20 0.49
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 2.07e-20 0.47
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 2.183e-20 0.48
EBPL_HUMAN EBPL Emopamil-binding protein-like 3.462e-20 0.32
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 7.729e-20 0.33
CHKA_HUMAN CHKA Choline kinase alpha 2.305e-19 0.33
CHLE_HORSE BCHE Cholinesterase 2.713e-19 0.40
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 3.429e-19 0.45
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 3.828e-19 0.43
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 3.768e-18 0.35
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.594e-17 0.43
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 1.11e-16 0.32
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.11e-16 0.47
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 2.22e-16 0.48
HRH2_HUMAN HRH2 Histamine H2 receptor 2.22e-16 0.45
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 3.331e-16 0.42
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 3.331e-16 0.46
MIP_LEGPN mip Outer membrane protein MIP 2.665e-15 0.37
H10_HUMAN H1-0 Histone H1.0 3.331e-15 0.29
HRH1_CAVPO HRH1 Histamine H1 receptor 3.442e-15 0.46
DRD2_RAT Drd2 D(2) dopamine receptor 3.997e-15 0.47
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 4.33e-15 0.34
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 5.551e-15 0.44
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 1.377e-14 0.48
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 1.799e-14 0.36
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 2.42e-14 0.35
CHIT1_MOUSE Chit1 Chitotriosidase-1 4.818e-14 0.29
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 5.984e-14 0.29
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 6.461e-14 0.49
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 6.706e-14 0.49
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 7.905e-14 0.43
SMYD2_HUMAN SMYD2 N-lysine methyltransferase SMYD2 1.084e-13 0.33
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 3.085e-13 0.40
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 3.407e-13 0.33
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 3.499e-13 0.37
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 3.922e-13 0.29
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 5.038e-13 0.36
ACES_RAT Ache Acetylcholinesterase 5.215e-13 0.46
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 7.203e-13 0.30
US28_HCMVA US28 G-protein coupled receptor homolog US28 1.089e-11 0.31
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 1.607e-11 0.31
CHIT1_HUMAN CHIT1 Chitotriosidase-1 1.794e-11 0.29
ESR1_HUMAN ESR1 Estrogen receptor 2.933e-11 0.36
MURA_ECOLI murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3.048e-11 0.30
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 4.153e-11 0.37
PPCE_MOUSE Prep Prolyl endopeptidase 1.647e-10 0.28
CHIA_HUMAN CHIA Acidic mammalian chitinase 1.979e-10 0.29
CHIA_MOUSE Chia Acidic mammalian chitinase 1.979e-10 0.29
ACES_MOUSE Ache Acetylcholinesterase 3.576e-10 0.34
LSS_HUMAN LSS Lanosterol synthase 5.067e-10 0.38
Q9JKC1_RAT Bche Carboxylic ester hydrolase 5.325e-10 0.41
MEN1_HUMAN MEN1 Menin 6.297e-10 0.30
DRD1_PIG DRD1 D(1A) dopamine receptor 1.132e-09 0.32
HRH1_RAT Hrh1 Histamine H1 receptor 1.239e-09 0.33
ACES_HUMAN ACHE Acetylcholinesterase 2.709e-09 0.54
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 3.055e-09 0.29
ACES_ANOGA Ace Acetylcholinesterase 3.299e-09 0.32
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 4.723e-09 0.43
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 4.995e-09 0.32
PPCE_BOVIN PREP Prolyl endopeptidase 5.048e-09 0.28
Q6L5J4_HUMAN FPRL2 FML2_HUMAN 5.137e-09 0.41
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 6.857e-09 0.33
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 7.05e-09 0.41
GPBAR_MOUSE Gpbar1 G-protein coupled bile acid receptor 1 9.317e-09 0.31
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 9.627e-09 0.35
PPOC_ORYSJ PPOX1 Protoporphyrinogen oxidase, chloroplastic 1.082e-08 0.29
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 1.134e-08 0.29
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.278e-08 0.45
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 2.023e-08 0.32
LMBL1_HUMAN L3MBTL1 Lethal(3)malignant brain tumor-like protein 1 2.745e-08 0.45
DPO1_THEAQ polA DNA polymerase I, thermostable 2.755e-08 0.33
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 2.97e-08 0.48
Q9FYV8_MAIZE Protoporphyrinogen oxidase 2.973e-08 0.32
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 3.171e-08 0.34
DRD3_CHLAE DRD3 D(3) dopamine receptor 3.452e-08 0.29
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 3.505e-08 0.29
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 5.06e-08 0.35
Q9WTR4_RAT Slc6a2 Transporter 7.775e-08 0.38
PPCE_RAT Prep Prolyl endopeptidase 7.802e-08 0.31
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 1.097e-07 0.33
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 1.664e-07 0.29
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 1.848e-07 0.33
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 2.352e-07 0.34
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 3.567e-07 0.35
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 3.819e-07 0.35
HRH2_CAVPO HRH2 Histamine H2 receptor 4.133e-07 0.46
OXDA_MOUSE Dao D-amino-acid oxidase 8.114e-07 0.33
TLR9_HUMAN TLR9 Toll-like receptor 9 9.086e-07 0.33
AMYP_PIG AMY2 Pancreatic alpha-amylase 1.071e-06 0.28
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 1.209e-06 0.34
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 1.209e-06 0.43
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.45e-06 0.30
ESR2_HUMAN ESR2 Estrogen receptor beta 1.52e-06 0.34
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 1.558e-06 0.35
NOX5_HUMAN NOX5 NADPH oxidase 5 1.732e-06 0.30
Q63380_RAT NET Transporter 2.556e-06 0.34
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 2.708e-06 0.41
ACES_BOVIN ACHE Acetylcholinesterase 3.16e-06 0.33
ACHP_LYMST Acetylcholine-binding protein 3.238e-06 0.33
Q865E1_MACMU HRH3 Histamine receptor H3 4.649e-06 0.41
IKKB_MOUSE Ikbkb Inhibitor of nuclear factor kappa-B kinase subunit beta 5.03e-06 0.30
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 5.556e-06 0.42
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 5.929e-06 0.36
SKN1_CAEEL skn-1 Protein skinhead-1 6.203e-06 0.35
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 6.905e-06 0.37

Curcumin

A4_HUMAN APP Amyloid-beta precursor protein 1.061e-88 1.00
MTSI_SPISQ sssIM CPG DNA methylase 3.251e-71 1.00
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 6.787e-58 1.00
LGUL_HUMAN GLO1 Lactoylglutathione lyase 4.988e-47 1.00
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 7.526e-47 1.00
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 8.746e-46 1.00
TLR4_MOUSE Tlr4 Toll-like receptor 4 4.782e-44 1.00
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 4.629e-39 1.00
CAH6_HUMAN CA6 Carbonic anhydrase 6 6.942e-33 1.00
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 2.049e-28 1.00
CAH7_HUMAN CA7 Carbonic anhydrase 7 5.992e-28 1.00
FOS_HUMAN FOS Proto-oncogene c-Fos 1.157e-24 1.00
CAH13_HUMAN CA13 Carbonic anhydrase 13 7.821e-21 1.00
BACE1_HUMAN BACE1 Beta-secretase 1 2.088e-20 1.00
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 3.321e-20 1.00
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.156e-19 1.00
DHI1_RAT Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 2.407e-19 1.00
CAH12_HUMAN CA12 Carbonic anhydrase 12 5.558e-18 1.00
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 1.019e-17 1.00
CAH9_HUMAN CA9 Carbonic anhydrase 9 4.83e-17 1.00
CAH4_HUMAN CA4 Carbonic anhydrase 4 1.11e-16 1.00
EP300_HUMAN EP300 Histone acetyltransferase p300 3.331e-16 1.00
CAH1_HUMAN CA1 Carbonic anhydrase 1 6.704e-13 1.00
CAH15_MOUSE Ca15 Carbonic anhydrase 15 4.212e-12 1.00
PTGES_HUMAN PTGES Prostaglandin E synthase 5.676e-11 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 7.694e-11 1.00
NRAM_I77AB Neuraminidase 1.839e-10 1.00
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 3.069e-10 1.00
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 3.355e-10 1.00
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 4.277e-08 1.00
TF_HUMAN F3 Tissue factor 5.443e-08 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 3.865e-06 1.00
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 2.929e-05 1.00
KPCE_HUMAN PRKCE Protein kinase C epsilon type 4.2e-05 1.00
AMPN_HUMAN ANPEP Aminopeptidase N 9.911e-05 1.00
DHI1_HUMAN HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 0.2012 1.00
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 6.291e-173 0.63
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 1.021e-121 0.48
CYSP_PLAFA Trophozoite cysteine proteinase 2.12e-110 0.46
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 6.468e-77 0.47
TAU_HUMAN MAPT Microtubule-associated protein tau 2.493e-70 0.89
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.376e-67 0.47
TNR1A_HUMAN TNFRSF1A Tumor necrosis factor receptor superfamily member 1A 1.497e-64 0.42
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 6.632e-64 0.73
PTN1_MOUSE Ptpn1 Tyrosine-protein phosphatase non-receptor type 1 1.712e-55 0.33
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 4.585e-53 0.53
GP183_MOUSE Gpr183 G-protein coupled receptor 183 1.558e-49 0.32
PACR_HUMAN ADCYAP1R1 Pituitary adenylate cyclase-activating polypeptide type I receptor 9.797e-47 0.33
NR0B2_HUMAN NR0B2 Nuclear receptor subfamily 0 group B member 2 6.755e-46 0.34
NANA_STREE nanA Sialidase A 1.368e-45 0.39
DCOR_HUMAN ODC1 Ornithine decarboxylase 4.012e-45 0.48
Q7ZJM1_9HIV1 pol Integrase 8.338e-45 0.91
TRPM5_HUMAN TRPM5 Transient receptor potential cation channel subfamily M member 5 1.865e-43 0.35
C5ISA2_SHEEP TUBA4A Tubulin alpha chain 5.166e-42 0.33
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 2.51e-41 0.51
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 5.588e-41 0.65
PACR_RAT Adcyap1r1 Pituitary adenylate cyclase-activating polypeptide type I receptor 3.824e-40 0.32
DYN1_HUMAN DNM1 Dynamin-1 4.705e-40 0.37
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 6.695e-39 0.49
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 3.08e-38 0.30
MMP2_RAT Mmp2 72 kDa type IV collagenase 3.56e-37 0.29
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 3.127e-36 0.42
MYOC_HUMAN MYOC Myocilin 7.177e-32 0.40
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 1.536e-31 0.47
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 3.985e-31 0.51
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 6.911e-31 0.46
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 7.128e-31 0.74
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 1.123e-29 0.62
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 1.282e-29 0.33
DHPR_HUMAN QDPR Dihydropteridine reductase 1.143e-28 0.39
ACES_ELEEL ache Acetylcholinesterase 1.264e-28 0.70
Q43570_TOBAC NtBBF1.1 Zn finger protein 6.769e-28 0.33
CHLE_HORSE BCHE Cholinesterase 1.148e-27 0.54
Q26964_TRYCR TCTS-154 Trans-sialidase 1.79e-27 0.34
Q49PX0_9POXV N1L N1L 4.724e-27 0.42
CAH14_HUMAN CA14 Carbonic anhydrase 14 4.443e-26 0.74
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 5.386e-24 0.37
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 9.584e-24 0.47
CAH13_MOUSE Ca13 Carbonic anhydrase 13 1.263e-23 0.61
KCNB1_HUMAN KCNB1 Potassium voltage-gated channel subfamily B member 1 2.847e-23 0.29
TF65_HUMAN RELA Transcription factor p65 3.136e-23 0.49
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 4.364e-23 0.43
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 1.402e-22 0.48
AHR_RABIT AHR Aryl hydrocarbon receptor 2.887e-22 0.29
GP183_HUMAN GPR183 G-protein coupled receptor 183 3.573e-22 0.32
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 3.91e-21 0.78
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 6.515e-21 0.30
TTHY_HUMAN TTR Transthyretin 9.705e-21 0.59
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 1.141e-20 0.32
MMP1_HUMAN MMP1 Interstitial collagenase 2.327e-20 0.52
CHLE_HUMAN BCHE Cholinesterase 2.639e-20 0.54
DHPR_RAT Qdpr Dihydropteridine reductase 2.905e-20 0.39
PPO2_AGABI PPO2 Polyphenol oxidase 2 3.649e-20 0.50
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 6.117e-20 0.34
JUN_HUMAN JUN Transcription factor AP-1 8.068e-20 0.73
Q9XYC7_PLAFA HDAC1 Histone deacetylase 2.72e-19 0.37
STXA_SHIDY stxA Shiga toxin subunit A 2.019e-18 0.40
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.554e-18 0.43
POL_RSVP gag-pol Gag-Pol polyprotein 7.088e-18 0.28
CAN_CANAL NCE103 Carbonic anhydrase 7.593e-18 0.46
MPRI_HUMAN IGF2R Cation-independent mannose-6-phosphate receptor 1.016e-17 0.39
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1.125e-17 0.33
MMP2_HUMAN MMP2 72 kDa type IV collagenase 4.155e-17 0.52
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 5.312e-17 0.35
CAH3_HUMAN CA3 Carbonic anhydrase 3 1.11e-16 0.45
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.11e-16 0.43
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 1.11e-16 0.46
ACPM_HUMAN NDUFAB1 Acyl carrier protein, mitochondrial 2.22e-16 0.31
CIA30_HUMAN NDUFAF1 Complex I intermediate-associated protein 30, mitochondrial 2.22e-16 0.31
NDUA1_HUMAN NDUFA1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 2.22e-16 0.31
NDUA2_HUMAN NDUFA2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 2.22e-16 0.31
NDUA3_HUMAN NDUFA3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 2.22e-16 0.31
NDUA5_HUMAN NDUFA5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 2.22e-16 0.31
NDUA6_HUMAN NDUFA6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 2.22e-16 0.31
NDUA7_HUMAN NDUFA7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 2.22e-16 0.31
NDUA8_HUMAN NDUFA8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 2.22e-16 0.31
NDUA9_HUMAN NDUFA9 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial 2.22e-16 0.31
NDUAA_HUMAN NDUFA10 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial 2.22e-16 0.31
NDUAB_HUMAN NDUFA11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 2.22e-16 0.31
NDUAC_HUMAN NDUFA12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 2.22e-16 0.31
NDUAD_HUMAN NDUFA13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 2.22e-16 0.31
NDUB1_HUMAN NDUFB1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 2.22e-16 0.31
NDUB2_HUMAN NDUFB2 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial 2.22e-16 0.31
NDUB3_HUMAN NDUFB3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 2.22e-16 0.31
NDUB4_HUMAN NDUFB4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 2.22e-16 0.31
NDUB5_HUMAN NDUFB5 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial 2.22e-16 0.31
NDUB6_HUMAN NDUFB6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 2.22e-16 0.31
NDUB7_HUMAN NDUFB7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 2.22e-16 0.31
NDUB8_HUMAN NDUFB8 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial 2.22e-16 0.31
NDUB9_HUMAN NDUFB9 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 2.22e-16 0.31
NDUBA_HUMAN NDUFB10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 2.22e-16 0.31
NDUBB_HUMAN NDUFB11 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial 2.22e-16 0.31
NDUC1_HUMAN NDUFC1 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial 2.22e-16 0.31
NDUC2_HUMAN NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2 2.22e-16 0.31
NDUF2_HUMAN NDUFAF2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 2.22e-16 0.31
NDUF3_HUMAN NDUFAF3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 2.22e-16 0.31
NDUF4_HUMAN NDUFAF4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 2.22e-16 0.31
NDUS1_HUMAN NDUFS1 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 2.22e-16 0.31
NDUS2_HUMAN NDUFS2 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 2.22e-16 0.31
NDUS3_HUMAN NDUFS3 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 2.22e-16 0.31
NDUS4_HUMAN NDUFS4 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 2.22e-16 0.31
NDUS5_HUMAN NDUFS5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 2.22e-16 0.31
NDUS6_HUMAN NDUFS6 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial 2.22e-16 0.31
NDUS7_HUMAN NDUFS7 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial 2.22e-16 0.31
NDUS8_HUMAN NDUFS8 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial 2.22e-16 0.31
NDUV1_HUMAN NDUFV1 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 2.22e-16 0.31
NDUV2_HUMAN NDUFV2 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 2.22e-16 0.31
NDUV3_HUMAN NDUFV3 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 2.22e-16 0.31
NU1M_HUMAN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 2.22e-16 0.31
NU2M_HUMAN MT-ND2 NADH-ubiquinone oxidoreductase chain 2 2.22e-16 0.31
NU3M_HUMAN MT-ND3 NADH-ubiquinone oxidoreductase chain 3 2.22e-16 0.31
NU4LM_HUMAN MT-ND4L NADH-ubiquinone oxidoreductase chain 4L 2.22e-16 0.31
NU5M_HUMAN MT-ND5 NADH-ubiquinone oxidoreductase chain 5 2.22e-16 0.31
NU6M_HUMAN MT-ND6 NADH-ubiquinone oxidoreductase chain 6 2.22e-16 0.31
NUA4L_HUMAN NDUFA4L2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 2.22e-16 0.31
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 2.22e-16 0.67
DUS3_HUMAN DUSP3 Dual specificity protein phosphatase 3 3.331e-16 0.38
NR1H4_HUMAN NR1H4 Bile acid receptor 5.551e-16 0.36
AOFA_MOUSE Maoa Amine oxidase [flavin-containing] A 6.661e-16 0.30
PTN7_HUMAN PTPN7 Tyrosine-protein phosphatase non-receptor type 7 6.661e-16 0.38
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 8.882e-16 0.48
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 9.992e-16 0.43
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 1.221e-15 0.41
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 1.443e-15 0.41
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 2.554e-15 0.33
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 3.331e-15 0.29
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 3.664e-15 0.39
HDAC1_HUMAN HDAC1 Histone deacetylase 1 3.997e-15 0.50
IMDH1_HUMAN IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 1.077e-14 0.36
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 1.277e-14 0.78
P89582_9HIV2 pol Integrase 1.987e-14 0.32
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 2.476e-14 0.39
MIF_HUMAN MIF Macrophage migration inhibitory factor 4.607e-14 0.36
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 5.329e-14 0.47
B4URF0_I33A0 Neuraminidase 8.349e-14 0.36
FUT7_HUMAN FUT7 Alpha-(1,3)-fucosyltransferase 7 9.504e-14 0.30
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 9.581e-14 0.42
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.559e-13 0.37
SHBG_HUMAN SHBG Sex hormone-binding globulin 2.466e-13 0.46
KLF5_HUMAN KLF5 Krueppel-like factor 5 3.822e-13 0.34
LYAG_RAT Gaa Lysosomal alpha-glucosidase 4.735e-13 0.42
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 4.957e-13 0.51
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 5.373e-13 0.34
HDAC8_HUMAN HDAC8 Histone deacetylase 8 5.801e-13 0.39
ACES_HUMAN ACHE Acetylcholinesterase 6.176e-13 0.54
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 7.048e-13 0.38
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 8.272e-13 0.45
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 9.167e-13 0.31
AK1A1_PIG AKR1A1 Aldo-keto reductase family 1 member A1 1.108e-12 0.31
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 1.466e-12 0.47
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 2.43e-12 0.34
HDAC2_HUMAN HDAC2 Histone deacetylase 2 2.436e-12 0.39
PERM_HUMAN MPO Myeloperoxidase 5.825e-12 0.47
LAT_MYCTU lat Probable L-lysine-epsilon aminotransferase 6.489e-12 0.35
GLR_HUMAN GCGR Glucagon receptor 6.655e-12 0.39
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 6.987e-12 0.46
HSF1_MOUSE Hsf1 Heat shock factor protein 1 2.062e-11 0.57
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 2.26e-11 0.50
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 2.985e-11 0.41
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 3.556e-11 0.39
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 4.403e-11 0.50
O96526_LEIMA CRK3 Cdc2-related kinase 5.117e-11 0.32
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 6.066e-11 0.33
HDA11_HUMAN HDAC11 Histone deacetylase 11 6.919e-11 0.33
NU4M_HUMAN MT-ND4 NADH-ubiquinone oxidoreductase chain 4 1.068e-10 0.31
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.105e-10 0.29
ACES_TETCF ache Acetylcholinesterase 1.757e-10 0.35
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 5.036e-10 0.31
RXRA_MOUSE Rxra Retinoic acid receptor RXR-alpha 6.6e-10 0.30
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 7.536e-10 0.89
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 7.636e-10 0.44
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 1.136e-09 0.53
Q76353_9HIV1 Integrase 1.236e-09 0.45
Q9ZTP8_MAIZE hd1b Histone deacetylase 1.261e-09 0.33
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 1.321e-09 0.34
CH10_HUMAN HSPE1 10 kDa heat shock protein, mitochondrial 1.52e-09 0.32
CH60_HUMAN HSPD1 60 kDa heat shock protein, mitochondrial 1.52e-09 0.32
RARB_HUMAN RARB Retinoic acid receptor beta 2.422e-09 0.33
AGAL_HUMAN GLA Alpha-galactosidase A 2.635e-09 0.29
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 2.801e-09 0.39
CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 2.917e-09 0.43
GLR_RAT Gcgr Glucagon receptor 3.313e-09 0.33
G6PT1_HUMAN SLC37A4 Glucose-6-phosphate exchanger SLC37A4 3.895e-09 0.31
A3EZJ3_9HEPC NS3 Genome polyprotein 5.58e-09 0.34
PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 7.658e-09 0.35
RARA_HUMAN RARA Retinoic acid receptor alpha 7.983e-09 0.33
HDAC6_HUMAN HDAC6 Histone deacetylase 6 8.386e-09 0.50
O49150_SOLTU Lipoxygenase 8.733e-09 0.45
FABH_ECOLI fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.056e-08 0.30
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 1.083e-08 0.31
STRP_STRP1 ska Streptokinase A 1.192e-08 0.53
NOX4_HUMAN NOX4 NADPH oxidase 4 1.194e-08 0.44
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 1.32e-08 0.34
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 1.341e-08 0.43
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.426e-08 0.41
Q9BHT9_PLABE G6PD-6PGL Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 1.589e-08 0.53
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 1.636e-08 0.34
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.92e-08 0.39
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.57e-08 0.39
Q932Y6_PSEAI bla(tem-2) Beta-lactamase 3.972e-08 0.89
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 5.356e-08 0.37
DPOL_HHV6U U38 DNA polymerase catalytic subunit 5.363e-08 0.28
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 5.465e-08 0.46
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 6.44e-08 0.29
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 7.456e-08 0.46
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 8.839e-08 0.45
CYSK_MYCTU cysK1 O-acetylserine sulfhydrylase 8.85e-08 0.35
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 9.402e-08 0.37
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 1.027e-07 0.38
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.035e-07 0.50
LUCI_PHOPY Luciferin 4-monooxygenase 1.12e-07 0.43
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.283e-07 0.40
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 1.332e-07 0.33
TLR9_HUMAN TLR9 Toll-like receptor 9 1.424e-07 0.89
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 1.628e-07 0.39
MET_HUMAN MET Hepatocyte growth factor receptor 1.893e-07 0.61
RECA_MYCTU recA Protein RecA 2.203e-07 0.48
SENP7_HUMAN SENP7 Sentrin-specific protease 7 2.412e-07 0.40
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 3.035e-07 0.33
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 3.205e-07 0.29
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 3.428e-07 0.86
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 4.36e-07 0.30
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 4.465e-07 0.35
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 4.524e-07 0.32
CP26B_HUMAN CYP26B1 Cytochrome P450 26B1 4.905e-07 0.29
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 6.286e-07 0.44
Q5TKS5_STAAU fabI Enoyl-ACP reductase 7.384e-07 0.32
BGAL_ECOLX lacZ Beta-galactosidase 1.127e-06 0.39
Q8IL32_PLAF7 Heat shock protein 90, putative 1.215e-06 0.53
COMT_RAT Comt Catechol O-methyltransferase 1.216e-06 0.37
SENP6_HUMAN SENP6 Sentrin-specific protease 6 1.29e-06 0.40
PDE5A_BOVIN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 1.393e-06 0.47
HDAC1_MOUSE Hdac1 Histone deacetylase 1 1.419e-06 0.35
RARG_HUMAN RARG Retinoic acid receptor gamma 1.495e-06 0.33
MAP2_HUMAN METAP2 Methionine aminopeptidase 2 1.519e-06 0.33
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 1.688e-06 0.42
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 1.714e-06 0.35
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 1.72e-06 0.39
AHR_HUMAN AHR Aryl hydrocarbon receptor 1.928e-06 0.29
NOX1_HUMAN NOX1 NADPH oxidase 1 1.989e-06 0.30
PDE4C_HUMAN PDE4C cAMP-specific 3',5'-cyclic phosphodiesterase 4C 2.021e-06 0.35
XBP1_HUMAN XBP1 X-box-binding protein 1 2.108e-06 0.37
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 2.685e-06 0.41
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 2.699e-06 0.38
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 2.719e-06 0.38
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 2.99e-06 0.32
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 3.168e-06 0.28
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 3.203e-06 0.29
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 4.083e-06 0.41
BLA2_BACCE blm Metallo-beta-lactamase type 2 4.749e-06 0.30
CCND3_HUMAN CCND3 G1/S-specific cyclin-D3 5.198e-06 0.41
GPR35_HUMAN GPR35 G-protein coupled receptor 35 5.82e-06 0.36
ERR1_HUMAN ESRRA Steroid hormone receptor ERR1 6.065e-06 0.29
HPSE_HUMAN HPSE Heparanase 6.337e-06 0.30
HDAC4_HUMAN HDAC4 Histone deacetylase 4 6.715e-06 0.38
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 6.746e-06 0.74
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 7.122e-06 0.38
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 7.435e-06 0.41
TLR1_MOUSE Tlr1 Toll-like receptor 1 7.581e-06 0.29
TLR2_MOUSE Tlr2 Toll-like receptor 2 7.581e-06 0.29
CP19A_HUMAN CYP19A1 Aromatase 8.517e-06 0.42
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 8.753e-06 0.76
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 8.819e-06 0.40
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 8.987e-06 0.35
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 9.636e-06 0.29

Tafamidis

TTHY_HUMAN TTR Transthyretin 1.982e-13 1.00
HPSE_HUMAN HPSE Heparanase 3.997e-93 0.45
CYC_HUMAN CYCS Cytochrome c 1.389e-44 0.35
G3V906_RAT Hcar1 Hydroxycarboxylic acid receptor 1 5.166e-42 0.33
DKK1_MOUSE Dkk1 Dickkopf-related protein 1 1.28e-40 0.32
SYEP_HUMAN EPRS1 Bifunctional glutamate/proline--tRNA ligase 1.102e-37 0.30
HIF1N_HUMAN HIF1AN Hypoxia-inducible factor 1-alpha inhibitor 2.435e-37 0.30
ESR1_MOUSE Esr1 Estrogen receptor 8.091e-33 0.44
ESR2_MOUSE Esr2 Estrogen receptor beta 8.091e-33 0.44
GP119_HUMAN GPR119 Glucose-dependent insulinotropic receptor 3.785e-32 0.48
SYPC_CANAX PRS Proline--tRNA ligase, cytoplasmic 8.822e-31 0.35
PLCB_HUMAN AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 3.215e-29 0.36
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 5.428e-29 0.33
Q38C41_TRYB2 Phosphotransferase 1.569e-27 0.32
Q44079_AERHY cphA2 Beta-lactamase 4.904e-24 0.30
CEPT1_HUMAN CEPT1 Choline/ethanolaminephosphotransferase 1 5.974e-21 0.32
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 1.654e-20 0.30
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 2.123e-20 0.28
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 2.697e-20 0.35
P4HA1_HUMAN P4HA1 Prolyl 4-hydroxylase subunit alpha-1 4.748e-20 0.32
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 1.11e-16 0.39
CSK2B_HUMAN CSNK2B Casein kinase II subunit beta 9.992e-16 0.39
GRM5_MOUSE Grm5 Metabotropic glutamate receptor 5 2.442e-15 0.29
KMO_HUMAN KMO Kynurenine 3-monooxygenase 2.899e-13 0.35
Q548M1_ECOLX groL 60 kDa chaperonin 3.286e-13 0.30
Q7BGE6_ECOLX groES 10 kDa chaperonin 3.286e-13 0.30
NOTUM_MOUSE Notum Palmitoleoyl-protein carboxylesterase NOTUM 3.32e-13 0.31
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 7.122e-13 0.34
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 1.445e-12 0.31
ESR2_RAT Esr2 Estrogen receptor beta 1.523e-12 0.44
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 4.114e-12 0.30
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 6.333e-12 0.36
NOTUM_HUMAN NOTUM Palmitoleoyl-protein carboxylesterase NOTUM 7.499e-12 0.31
Q2PCB5_DICLA ca Carbonic anhydrase 9.095e-12 0.32
REST_BORBU resT Telomere resolvase ResT 1.23e-11 0.28
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 1.986e-11 0.30
ESR1_RAT Esr1 Estrogen receptor 2.317e-11 0.44
TLR9_HUMAN TLR9 Toll-like receptor 9 2.542e-11 0.34
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 3.482e-10 0.34
ESR2_HUMAN ESR2 Estrogen receptor beta 3.69e-10 0.44
CETP_HUMAN CETP Cholesteryl ester transfer protein 5.335e-10 0.37
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 6.26e-10 0.30
EST1_RABIT Liver carboxylesterase 1 7.373e-10 0.32
FABP5_HUMAN FABP5 Fatty acid-binding protein 5 7.982e-10 0.32
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 1.738e-09 0.30
AAPK2_HUMAN PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 3.493e-09 0.32
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 6.535e-09 0.36
Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 6.548e-09 0.29
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 1.038e-08 0.30
LRP6_HUMAN LRP6 Low-density lipoprotein receptor-related protein 6 1.349e-08 0.32
AAKG1_HUMAN PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 1.663e-08 0.32
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 1.782e-08 0.42
AMPC_ECOLI ampC Beta-lactamase 4.341e-08 0.35
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 4.451e-08 0.32
PE2R1_RAT Ptger1 Prostaglandin E2 receptor EP1 subtype 5.44e-08 0.35
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 8.387e-08 0.37
ESR1_HUMAN ESR1 Estrogen receptor 8.796e-08 0.44
ACMSD_HUMAN ACMSD 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase 1.031e-07 0.29
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 1.326e-07 0.32
KDM5B_HUMAN KDM5B Lysine-specific demethylase 5B 1.817e-07 0.30
SENP7_HUMAN SENP7 Sentrin-specific protease 7 1.989e-07 0.42
KS6B2_HUMAN RPS6KB2 Ribosomal protein S6 kinase beta-2 4.296e-07 0.30
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 4.364e-07 0.36
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 8.439e-07 0.34
RFA1_HUMAN RPA1 Replication protein A 70 kDa DNA-binding subunit 9.256e-07 0.29
SKN1_CAEEL skn-1 Protein skinhead-1 9.458e-07 0.41
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 1.177e-06 0.30
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 1.551e-06 0.30
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 2.121e-06 0.44
CTRC_HUMAN CTRC Chymotrypsin-C 2.249e-06 0.35
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 2.692e-06 0.34
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 2.761e-06 0.37
RARG_HUMAN RARG Retinoic acid receptor gamma 3.205e-06 0.31
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 4.149e-06 0.30
RARB_HUMAN RARB Retinoic acid receptor beta 4.291e-06 0.31
NR1H4_HUMAN NR1H4 Bile acid receptor 4.399e-06 0.34
RARA_HUMAN RARA Retinoic acid receptor alpha 4.53e-06 0.30
KDM4B_HUMAN KDM4B Lysine-specific demethylase 4B 8.58e-06 0.29

Triheptanoin

P2Y10_HUMAN P2RY10 Putative P2Y purinoceptor 10 4.861e-154 0.46
TLR2_HUMAN TLR2 Toll-like receptor 2 1.683e-151 0.58
GP174_HUMAN GPR174 Probable G-protein coupled receptor 174 5.841e-123 0.46
CQSS_VIBCH cqsS CAI-1 autoinducer sensor kinase/phosphatase CqsS 1.765e-118 0.43
LPAR4_HUMAN LPAR4 Lysophosphatidic acid receptor 4 2.208e-103 0.54
GPR34_HUMAN GPR34 Probable G-protein coupled receptor 34 9.919e-90 0.46
LPAR6_HUMAN LPAR6 Lysophosphatidic acid receptor 6 1.075e-79 0.54
MCAT_HUMAN SLC25A20 Mitochondrial carnitine/acylcarnitine carrier protein 2.542e-67 0.54
KPCA_BOVIN PRKCA Protein kinase C alpha type 3.155e-65 0.84
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 3.368e-63 0.77
LPAR4_MOUSE Lpar4 Lysophosphatidic acid receptor 4 1.832e-58 0.47
MPIP2_MOUSE Cdc25b M-phase inducer phosphatase 2 1.27e-55 0.35
POLI_MOUSE Poli DNA polymerase iota 2.484e-53 0.35
LPAR1_MOUSE Lpar1 Lysophosphatidic acid receptor 1 2.257e-49 0.33
DPOLM_HUMAN POLM DNA-directed DNA/RNA polymerase mu 1.389e-44 0.35
TDT_BOVIN DNTT DNA nucleotidylexotransferase 1.389e-44 0.35
KPCL_MOUSE Prkch Protein kinase C eta type 1.198e-42 0.84
PA2A1_NAJMO Acidic phospholipase A2 CM-I 3.568e-41 0.33
A1ZA98_DROME Jhe Carboxylic ester hydrolase 4.563e-41 0.41
PA2GC_HUMAN PLA2G2C Putative inactive group IIC secretory phospholipase A2 2.273e-40 0.33
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 6.214e-40 0.39
ACER2_HUMAN ACER2 Alkaline ceramidase 2 7.142e-37 0.29
Q95Z89_LEIMA Top1B DNA topoisomerase type IB small subunit 1.332e-36 0.29
ADH7_HUMAN ADH7 All-trans-retinol dehydrogenase [NAD(+)] ADH7 3.875e-36 0.29
KPCA_HUMAN PRKCA Protein kinase C alpha type 2.549e-34 0.84
POLH_HUMAN POLH DNA polymerase eta 3.47e-34 0.35
Q6UB75_PIG Group VII phospholipase A2 3.724e-34 0.32
CP2E1_HUMAN CYP2E1 Cytochrome P450 2E1 7.237e-33 0.33
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 8.462e-33 0.55
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 2.095e-32 0.36
PA21B_PIG PLA2G1B Phospholipase A2, major isoenzyme 1.437e-31 0.42
Q9GPG0_MANSE Carboxylic ester hydrolase 5.395e-30 0.37
Q197X6_TOXGO FPPS Farnesyl diphosphate synthase 1.874e-29 0.34
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 2.374e-29 0.37
ACPM_HUMAN NDUFAB1 Acyl carrier protein, mitochondrial 4.137e-29 0.28
CIA30_HUMAN NDUFAF1 Complex I intermediate-associated protein 30, mitochondrial 4.137e-29 0.28
NDUA1_HUMAN NDUFA1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 4.137e-29 0.28
NDUA2_HUMAN NDUFA2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 4.137e-29 0.28
NDUA3_HUMAN NDUFA3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 4.137e-29 0.28
NDUA5_HUMAN NDUFA5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 4.137e-29 0.28
NDUA6_HUMAN NDUFA6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 4.137e-29 0.28
NDUA7_HUMAN NDUFA7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 4.137e-29 0.28
NDUA8_HUMAN NDUFA8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 4.137e-29 0.28
NDUA9_HUMAN NDUFA9 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial 4.137e-29 0.28
NDUAA_HUMAN NDUFA10 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial 4.137e-29 0.28
NDUAB_HUMAN NDUFA11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 4.137e-29 0.28
NDUAC_HUMAN NDUFA12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 4.137e-29 0.28
NDUAD_HUMAN NDUFA13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 4.137e-29 0.28
NDUB1_HUMAN NDUFB1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 4.137e-29 0.28
NDUB2_HUMAN NDUFB2 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial 4.137e-29 0.28
NDUB3_HUMAN NDUFB3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 4.137e-29 0.28
NDUB4_HUMAN NDUFB4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 4.137e-29 0.28
NDUB5_HUMAN NDUFB5 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial 4.137e-29 0.28
NDUB6_HUMAN NDUFB6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 4.137e-29 0.28
NDUB7_HUMAN NDUFB7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 4.137e-29 0.28
NDUB8_HUMAN NDUFB8 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial 4.137e-29 0.28
NDUB9_HUMAN NDUFB9 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 4.137e-29 0.28
NDUBA_HUMAN NDUFB10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 4.137e-29 0.28
NDUBB_HUMAN NDUFB11 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial 4.137e-29 0.28
NDUC1_HUMAN NDUFC1 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial 4.137e-29 0.28
NDUC2_HUMAN NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2 4.137e-29 0.28
NDUF2_HUMAN NDUFAF2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 4.137e-29 0.28
NDUF3_HUMAN NDUFAF3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 4.137e-29 0.28
NDUF4_HUMAN NDUFAF4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 4.137e-29 0.28
NDUS1_HUMAN NDUFS1 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 4.137e-29 0.28
NDUS2_HUMAN NDUFS2 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 4.137e-29 0.28
NDUS3_HUMAN NDUFS3 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 4.137e-29 0.28
NDUS4_HUMAN NDUFS4 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 4.137e-29 0.28
NDUS5_HUMAN NDUFS5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 4.137e-29 0.28
NDUS6_HUMAN NDUFS6 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial 4.137e-29 0.28
NDUS7_HUMAN NDUFS7 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial 4.137e-29 0.28
NDUS8_HUMAN NDUFS8 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial 4.137e-29 0.28
NDUV1_HUMAN NDUFV1 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 4.137e-29 0.28
NDUV2_HUMAN NDUFV2 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 4.137e-29 0.28
NDUV3_HUMAN NDUFV3 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 4.137e-29 0.28
NU1M_HUMAN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 4.137e-29 0.28
NU2M_HUMAN MT-ND2 NADH-ubiquinone oxidoreductase chain 2 4.137e-29 0.28
NU3M_HUMAN MT-ND3 NADH-ubiquinone oxidoreductase chain 3 4.137e-29 0.28
NU4LM_HUMAN MT-ND4L NADH-ubiquinone oxidoreductase chain 4L 4.137e-29 0.28
NU5M_HUMAN MT-ND5 NADH-ubiquinone oxidoreductase chain 5 4.137e-29 0.28
NU6M_HUMAN MT-ND6 NADH-ubiquinone oxidoreductase chain 6 4.137e-29 0.28
NUA4L_HUMAN NDUFA4L2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 4.137e-29 0.28
PA2GA_MOUSE Pla2g2a Phospholipase A2, membrane associated 2.453e-28 0.36
PPM1A_HUMAN PPM1A Protein phosphatase 1A 2.586e-28 0.35
ALF_CANAL FBA1 Fructose-bisphosphate aldolase 3.926e-28 0.37
EST1_RABIT Liver carboxylesterase 1 1.27e-27 0.43
PA2G5_HUMAN PLA2G5 Calcium-dependent phospholipase A2 2.762e-27 0.36
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 1.316e-26 0.54
POLK_HUMAN POLK DNA polymerase kappa 2.123e-26 0.35
KPCA_RAT Prkca Protein kinase C alpha type 2.698e-26 0.38
PA2GA_RABIT PLA2G2A Phospholipase A2, membrane associated 9.886e-26 0.32
Q5HMD9_STAEQ murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 2.901e-25 0.31
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 4.036e-25 0.77
Q8WS26_TRYCR Farnesyl diphosphate synthase 3.409e-24 0.34
PA2G5_MOUSE Pla2g5 Calcium-dependent phospholipase A2 1.538e-23 0.36
EST2C_MOUSE Ces2c Acylcarnitine hydrolase 2.334e-23 0.30
EST2_HUMAN CES2 Cocaine esterase 1.082e-22 0.43
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 1.665e-22 0.28
PA2GA_RAT Pla2g2a Phospholipase A2, membrane associated 3.209e-22 0.36
A85C_MYCTU fbpC Diacylglycerol acyltransferase/mycolyltransferase Ag85C 8.238e-21 0.32
AMPN_ECOLI pepN Aminopeptidase N 1.446e-19 0.31
SPTC2_HUMAN SPTLC2 Serine palmitoyltransferase 2 5.19e-19 0.30
NU4M_HUMAN MT-ND4 NADH-ubiquinone oxidoreductase chain 4 9.064e-19 0.28
Q9BJJ9_PLAFA FabI Enoyl-ACP reductase 2.898e-18 0.29
D5FGE8_TRYCR POT1.5 Putative amino acid permease/transporter 3.334e-18 0.29
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 7.07e-18 0.54
GSTM1_HUMAN GSTM1 Glutathione S-transferase Mu 1 9.771e-18 0.28
EST1_HUMAN CES1 Liver carboxylesterase 1 4.73e-17 0.43
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.665e-15 0.33
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 3.331e-15 0.77
MGLL_RAT Mgll Monoglyceride lipase 4.33e-15 0.34
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 1.765e-14 0.35
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 3.653e-14 0.55
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 3.753e-14 0.35
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.129e-13 0.61
DYN1_HUMAN DNM1 Dynamin-1 1.642e-13 0.33
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 2.367e-13 0.33
GPR34_MOUSE Gpr34 Probable G-protein coupled receptor 34 2.446e-13 0.40
KPCE_HUMAN PRKCE Protein kinase C epsilon type 7.602e-13 0.84
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 2.307e-12 0.30
ERG1_RAT Sqle Squalene monooxygenase 2.988e-12 0.33
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 4.314e-12 0.33
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 6.804e-12 0.46
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 7.328e-12 0.37
GNAI1_HUMAN GNAI1 Guanine nucleotide-binding protein G(i) subunit alpha-1 7.334e-12 0.29
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 2.453e-11 0.35
LYAM3_HUMAN SELP P-selectin 4.536e-11 0.54
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 8.149e-11 0.38
P2Y10_MOUSE P2ry10 Putative P2Y purinoceptor 10 8.735e-11 0.40
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.415e-10 0.28
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 2.488e-10 0.38
KPCD_MOUSE Prkcd Protein kinase C delta type 2.633e-10 0.50
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 4.42e-10 0.37
CP74A_ARATH CYP74A Allene oxide synthase, chloroplastic 4.661e-10 0.29
DPOLL_HUMAN POLL DNA polymerase lambda 6.896e-10 0.35
PAOX_HUMAN PAOX Peroxisomal N(1)-acetyl-spermine/spermidine oxidase 7.541e-10 0.29
TLR4_HUMAN TLR4 Toll-like receptor 4 8.965e-10 0.29
EST1_PIG Liver carboxylesterase 1.379e-09 0.37
GGPPS_HUMAN GGPS1 Geranylgeranyl pyrophosphate synthase 2.025e-09 0.29
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 2.791e-09 0.29
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 3.442e-09 0.28
ADH1B_HUMAN ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH1B 3.598e-09 0.29
KPCA_MOUSE Prkca Protein kinase C alpha type 1.478e-08 0.33
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.957e-08 0.41
O07911_STAAU agrC AgrC 2.237e-08 0.30
NAAA_HUMAN NAAA N-acylethanolamine-hydrolyzing acid amidase 2.24e-08 0.43
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 2.79e-08 0.42
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 4.256e-08 0.30
KDM5A_HUMAN KDM5A Lysine-specific demethylase 5A 5.447e-08 0.33
AMPL_HUMAN LAP3 Cytosol aminopeptidase 7.597e-08 0.32
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 7.951e-08 0.33
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 8.352e-08 0.29
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 9.579e-08 0.49
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 1.365e-07 0.28
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 1.408e-07 0.30
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 2.367e-07 0.33
DPOLB_RAT Polb DNA polymerase beta 2.429e-07 0.35
KPCG_RAT Prkcg Protein kinase C gamma type 2.74e-07 0.84
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 2.972e-07 0.54
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.065e-06 0.42
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 1.271e-06 0.29
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 1.654e-06 0.32
DPOLB_HUMAN POLB DNA polymerase beta 1.71e-06 0.38
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 2.741e-06 0.29

Rebamipide

CP51_TRYCC CYP51 Sterol 14-alpha demethylase 3.729e-138 0.43
TYSY_MOUSE Tyms Thymidylate synthase 1.766e-88 0.34
PUR2_HUMAN GART Trifunctional purine biosynthetic protein adenosine-3 2.398e-83 0.36
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 4.739e-83 0.42
FOLC_HUMAN FPGS Folylpolyglutamate synthase, mitochondrial 8.206e-82 0.34
EDNRB_RAT Ednrb Endothelin receptor type B 1.914e-77 0.37
PUR2_MOUSE Gart Trifunctional purine biosynthetic protein adenosine-3 8.185e-71 0.36
FOLC_MOUSE Fpgs Folylpolyglutamate synthase, mitochondrial 7.521e-69 0.33
DYR_MOUSE Dhfr Dihydrofolate reductase 3.967e-67 0.32
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 1.849e-66 0.48
NEP_RABIT MME Neprilysin 4.106e-64 0.42
ECE1_BOVIN ECE1 Endothelin-converting enzyme 1 1.534e-63 0.37
EDNRA_MOUSE Ednra Endothelin-1 receptor 1.69e-61 0.33
KISSR_HUMAN KISS1R KiSS-1 receptor 1.48e-60 0.40
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 2.602e-52 0.36
TYSY_HUMAN TYMS Thymidylate synthase 3.259e-51 0.33
SYUA_HUMAN SNCA Alpha-synuclein 3.861e-50 0.37
MMP11_MOUSE Mmp11 Stromelysin-3 9.732e-50 0.30
BLA1_STEMA Metallo-beta-lactamase L1 type 3 1.61e-49 0.39
ITB7_HUMAN ITGB7 Integrin beta-7 8.445e-49 0.35
DYR_ENTFC folA Dihydrofolate reductase 1.224e-48 0.32
EDNRA_PIG EDNRA Endothelin-1 receptor 8.829e-48 0.36
NEP_PIG MME Neprilysin 1.753e-43 0.42
IL1RA_MOUSE Il1rn Interleukin-1 receptor antagonist protein 1.756e-43 0.35
ACE_RAT Ace Angiotensin-converting enzyme 1.686e-42 0.42
E2QDN0_ECOLX thyA Thymidylate synthase 5.162e-42 0.30
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.105e-41 0.47
DYR_HUMAN DHFR Dihydrofolate reductase 9.225e-41 0.35
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 2.984e-40 0.34
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 6.845e-40 0.45
MC3R_HUMAN MC3R Melanocortin receptor 3 2.227e-39 0.42
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 2.817e-39 0.55
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 1.701e-38 0.42
NEP_HUMAN MME Neprilysin 1.778e-38 0.40
Q9MYJ9_RABIT CCR1 Chemokine receptor 1.947e-38 0.30
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 1.354e-37 0.47
ECE1_RAT Ece1 Endothelin-converting enzyme 1 2.198e-37 0.41
BODG_PSESK Gamma-butyrobetaine dioxygenase 3.997e-37 0.46
TYSY_RAT Tyms Thymidylate synthase 9.401e-37 0.30
DPO3B_ECOLI dnaN Beta sliding clamp 2.333e-36 0.29
MC4R_HUMAN MC4R Melanocortin receptor 4 4.401e-36 0.42
CCKAR_RAT Cckar Cholecystokinin receptor type A 7.722e-36 0.48
FOLC_ECOLI folC Dihydrofolate synthase/folylpolyglutamate synthase 1.71e-35 0.28
ACE_HUMAN ACE Angiotensin-converting enzyme 1.822e-35 0.47
FOLR2_HUMAN FOLR2 Folate receptor beta 1.566e-33 0.34
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 1.45e-32 0.49
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 2.541e-32 0.37
ITB1_HUMAN ITGB1 Integrin beta-1 7.164e-32 0.42
ITA4_HUMAN ITGA4 Integrin alpha-4 8.182e-32 0.42
CATL2_HUMAN CTSV Cathepsin L2 4.737e-31 0.37
Q6DMN0_TOXGO CPL Cathepsin L 5.052e-31 0.33
CBPA1_HUMAN CPA1 Carboxypeptidase A1 5.878e-31 0.34
GRM5_MOUSE Grm5 Metabotropic glutamate receptor 5 1.138e-30 0.30
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 2.237e-30 0.40
DYR_LACCA folA Dihydrofolate reductase 3.458e-30 0.32
EDNRB_PIG EDNRB Endothelin receptor type B 9.856e-30 0.39
MMP11_HUMAN MMP11 Stromelysin-3 1.164e-29 0.29
ITB2_HUMAN ITGB2 Integrin beta-2 7.993e-29 0.48
LMCPB_LEIME LMCPB Cysteine proteinase B 8.417e-29 0.28
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 1.239e-28 0.46
PCFT_HUMAN SLC46A1 Proton-coupled folate transporter 3.183e-28 0.34
EDNRA_HUMAN EDNRA Endothelin-1 receptor 7.058e-28 0.37
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 7.798e-27 0.45
THER_BACTH npr Thermolysin 3.705e-26 0.40
SYM_ECOLI metG Methionine--tRNA ligase 6.743e-26 0.35
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 8.611e-26 0.45
A2TEF2_LEIIN CYP51 Putative lanosterol 14-alpha-demethylase 1.105e-25 0.32
NEP_MOUSE Mme Neprilysin 1.177e-25 0.30
TYSY_LACCA thyA Thymidylate synthase 1.561e-24 0.31
ITAL_HUMAN ITGAL Integrin alpha-L 1.78e-24 0.48
FOLR1_HUMAN FOLR1 Folate receptor alpha 2.983e-24 0.34
ENL_HUMAN MLLT1 Protein ENL 4.035e-23 0.28
TYRO_HUMAN TYR Tyrosinase 4.204e-23 0.35
NMBR_HUMAN NMBR Neuromedin-B receptor 2.372e-22 0.32
UR2R_HUMAN UTS2R Urotensin-2 receptor 2.882e-22 0.38
RIR1_MYCTU nrdE Ribonucleoside-diphosphate reductase subunit alpha 5.481e-22 0.35
ITA5_HUMAN ITGA5 Integrin alpha-5 1.645e-21 0.33
MMP2_HUMAN MMP2 72 kDa type IV collagenase 1.906e-21 0.45
NEP_RAT Mme Neprilysin 2.83e-21 0.41
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 5.474e-21 0.36
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 8.982e-21 0.32
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 1.127e-20 0.40
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 1.252e-20 0.40
PLD2_HUMAN PLD2 Phospholipase D2 1.82e-20 0.36
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 3.313e-20 0.32
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 3.496e-20 0.35
TSPO_RAT Tspo Translocator protein 6.015e-20 0.34
CP51_CANAL ERG11 Lanosterol 14-alpha demethylase 6.896e-20 0.32
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 7.566e-20 0.36
MMP8_RAT Mmp8 Neutrophil collagenase 1.543e-19 0.32
ELAS_PSEAE lasB Elastase 2.547e-19 0.34
PLD1_HUMAN PLD1 Phospholipase D1 2.897e-19 0.36
ICAM1_HUMAN ICAM1 Intercellular adhesion molecule 1 3.561e-19 0.48
CAH4_BOVIN CA4 Carbonic anhydrase 4 3.693e-19 0.44
CAH2_HUMAN CA2 Carbonic anhydrase 2 3.851e-19 0.48
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 1.523e-18 0.29
GHSR_RAT Ghsr Growth hormone secretagogue receptor type 1 1.564e-18 0.32
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 3.322e-18 0.37
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 3.813e-18 0.30
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 5.88e-18 0.36
SO1A3_RAT Slco1a3 Solute carrier organic anion transporter family member 1A3 8.104e-18 0.28
CATL1_BOVIN CTSL Cathepsin L1 9.937e-18 0.33
PLD1_RAT Pld1 Phospholipase D1 1.179e-17 0.33
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 1.181e-17 0.33
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 1.336e-17 0.32
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 2.308e-17 0.33
D2K2A8_9HEPC NS4A Non-structural protein 4A 3.087e-17 0.33
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 1.11e-16 0.39
CATL1_HUMAN CTSL Cathepsin L1 1.11e-16 0.37
CNR1_HUMAN CNR1 Cannabinoid receptor 1 1.11e-16 0.38
HDAC2_HUMAN HDAC2 Histone deacetylase 2 1.11e-16 0.39
MMP8_HUMAN MMP8 Neutrophil collagenase 1.11e-16 0.35
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 2.22e-16 0.42
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 3.331e-16 0.39
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 4.441e-16 0.30
DYR_RAT Dhfr Dihydrofolate reductase 5.551e-16 0.32
DNMT1_MOUSE Dnmt1 DNA (cytosine-5)-methyltransferase 1 7.772e-16 0.30
KLKB1_HUMAN KLKB1 Plasma kallikrein 7.772e-16 0.39
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 1.998e-15 0.31
CATB_HUMAN CTSB Cathepsin B 2.776e-15 0.39
MC5R_MOUSE Mc5r Melanocortin receptor 5 2.998e-15 0.31
GLI2_HUMAN GLI2 Zinc finger protein GLI2 4.441e-15 0.29
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 9.659e-15 0.33
POLG_HRV16 Genome polyprotein 1.676e-14 0.32
LPXC_ECOLI lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 3.375e-14 0.37
S19A1_HUMAN SLC19A1 Reduced folate transporter 4.03e-14 0.31
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 9.392e-14 0.31
FA11_HUMAN F11 Coagulation factor XI 1.231e-13 0.54
ADA12_HUMAN ADAM12 Disintegrin and metalloproteinase domain-containing protein 12 1.242e-13 0.30
ACE_MOUSE Ace Angiotensin-converting enzyme 1.317e-13 0.29
CBPA1_BOVIN CPA1 Carboxypeptidase A1 3.155e-13 0.30
THB_RAT Thrb Thyroid hormone receptor beta 4.1e-13 0.30
CAH3_BOVIN CA3 Carbonic anhydrase 3 5.229e-13 0.30
HDAC3_HUMAN HDAC3 Histone deacetylase 3 7.387e-13 0.39
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 7.442e-13 0.55
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 7.548e-13 0.32
C3SWJ7_ECOLX thyA Thymidylate synthase 1.067e-12 0.32
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 1.626e-12 0.32
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 1.702e-12 0.31
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 2.095e-12 0.33
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 3.091e-12 0.30
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 3.295e-12 0.34
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 4.412e-12 0.36
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 4.493e-12 0.30
CAH1_HUMAN CA1 Carbonic anhydrase 1 5.545e-12 0.47
MDM4_HUMAN MDM4 Protein Mdm4 5.908e-12 0.41
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 6.938e-12 0.37
NK2R_MESAU TACR2 Substance-K receptor 7.555e-12 0.32
MC4R_MOUSE Mc4r Melanocortin receptor 4 8.697e-12 0.31
A3EZI9_9HEPC NS3 Genome polyprotein 1.213e-11 0.33
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 1.235e-11 0.33
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 1.244e-11 0.29
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 1.498e-11 0.31
TYTR_LEIDO TPR Trypanothione reductase 1.537e-11 0.28
Q8JXU8_9HEPC NS5B RNA-directed RNA polymerase 1.992e-11 0.40
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 2.018e-11 0.32
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 2.549e-11 0.30
MTSI_SPISQ sssIM CPG DNA methylase 4.93e-11 0.35
CAN_CANAL NCE103 Carbonic anhydrase 5.523e-11 0.32
PADI2_HUMAN PADI2 Protein-arginine deiminase type-2 6.177e-11 0.32
MMP1_HUMAN MMP1 Interstitial collagenase 8.822e-11 0.35
Q3Y5H1_9GAMC 3C-like protease 1.028e-10 0.36
OXDA_RAT Dao D-amino-acid oxidase 1.131e-10 0.30
PADI1_HUMAN PADI1 Protein-arginine deiminase type-1 1.517e-10 0.31
PADI3_HUMAN PADI3 Protein-arginine deiminase type-3 1.517e-10 0.31
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 1.519e-10 0.32
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 2.96e-10 0.43
POLG_DEN26 Genome polyprotein 3.133e-10 0.32
CD36_RAT Cd36 Platelet glycoprotein 4 3.289e-10 0.31
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 4.191e-10 0.32
GHRHR_RAT Ghrhr Growth hormone-releasing hormone receptor 4.64e-10 0.30
ACE_RABIT ACE Angiotensin-converting enzyme 9.522e-10 0.49
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 1.032e-09 0.36
MENB_MYCTU menB 1,4-dihydroxy-2-naphthoyl-CoA synthase 1.045e-09 0.28
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 1.573e-09 0.36
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.847e-09 0.39
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 2.15e-09 0.35
CATS_HUMAN CTSS Cathepsin S 2.234e-09 0.37
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 2.284e-09 0.33
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 2.948e-09 0.31
TIMP3_RAT Timp3 Metalloproteinase inhibitor 3 3.181e-09 0.32
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 3.246e-09 0.28
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 3.307e-09 0.39
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 3.534e-09 0.34
GASR_BOVIN CCKBR Gastrin/cholecystokinin type B receptor 4.706e-09 0.30
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 5.637e-09 0.31
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 5.815e-09 0.31
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 6.031e-09 0.33
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 6.031e-09 0.33
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 6.691e-09 0.30
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 1.035e-08 0.30
MMP9_RAT Mmp9 Matrix metalloproteinase-9 1.066e-08 0.32
CATK_HUMAN CTSK Cathepsin K 1.265e-08 0.37
PAPA1_CARPA Papain 1.338e-08 0.33
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 1.738e-08 0.43
DRTS_TOXGO Bifunctional dihydrofolate reductase-thymidylate synthase 2.181e-08 0.32
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 2.311e-08 0.30
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 2.311e-08 0.30
DPOL_HHV6U U38 DNA polymerase catalytic subunit 2.696e-08 0.29
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 3.913e-08 0.32
GLI1_HUMAN GLI1 Zinc finger protein GLI1 3.985e-08 0.29
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 4.761e-08 0.30
CTRA_BOVIN Chymotrypsinogen A 5.207e-08 0.37
NK1R_CAVPO TACR1 Substance-P receptor 5.445e-08 0.33
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 6.159e-08 0.36
EDNRB_HUMAN EDNRB Endothelin receptor type B 6.175e-08 0.38
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 6.236e-08 0.34
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 6.408e-08 0.36
DYR_CHICK DHFR Dihydrofolate reductase 7.09e-08 0.28
NK1R_HUMAN TACR1 Substance-P receptor 7.325e-08 0.52
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 8.015e-08 0.32
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 9.364e-08 0.41
ITAV_HUMAN ITGAV Integrin alpha-V 1.013e-07 0.32
POLG_WNV Genome polyprotein 1.123e-07 0.32
KMO_RAT Kmo Kynurenine 3-monooxygenase 1.189e-07 0.30
ITB3_HUMAN ITGB3 Integrin beta-3 1.211e-07 0.42
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 1.243e-07 0.30
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 1.243e-07 0.30
MMP26_HUMAN MMP26 Matrix metalloproteinase-26 1.276e-07 0.30
CTRB_BOVIN Chymotrypsinogen B 1.452e-07 0.29
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 1.663e-07 0.30
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 1.709e-07 0.29
AMPN_PIG ANPEP Aminopeptidase N 1.994e-07 0.32
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 2.198e-07 0.30
ADCY5_HUMAN ADCY5 Adenylate cyclase type 5 2.479e-07 0.31
UCHL1_HUMAN UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1 3.205e-07 0.29
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 3.244e-07 0.31
MC3R_MOUSE Mc3r Melanocortin receptor 3 5.795e-07 0.30
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 7.379e-07 0.33
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 7.543e-07 0.30
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 7.569e-07 0.34
SENP1_HUMAN SENP1 Sentrin-specific protease 1 8.63e-07 0.31
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 8.736e-07 0.33
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 8.752e-07 0.30
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 9.164e-07 0.34
V1AR_RAT Avpr1a Vasopressin V1a receptor 9.948e-07 0.30
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 1.042e-06 0.28
PRKX_HUMAN PRKX cAMP-dependent protein kinase catalytic subunit PRKX 1.123e-06 0.35
CAN1_RAT Capn1 Calpain-1 catalytic subunit 1.184e-06 0.33
PRIO_SHEEP PRNP Major prion protein 1.201e-06 0.31
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 1.335e-06 0.42
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.448e-06 0.33
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 1.57e-06 0.32
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 1.621e-06 0.32
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 1.643e-06 0.34
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 1.869e-06 0.29
TPH1_HUMAN TPH1 Tryptophan 5-hydroxylase 1 2.132e-06 0.30
FNTA_HUMAN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 2.28e-06 0.34
HDAC6_MOUSE Hdac6 Histone deacetylase 6 2.383e-06 0.34
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 2.687e-06 0.41
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 2.794e-06 0.30
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 2.834e-06 0.36
PGTB1_HUMAN PGGT1B Geranylgeranyl transferase type-1 subunit beta 3.184e-06 0.29
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 3.376e-06 0.34
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 3.559e-06 0.29
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 3.563e-06 0.30
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 3.597e-06 0.28
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 4.182e-06 0.38
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 4.4e-06 0.30
LUCI_AQULA Luciferin 4-monooxygenase 4.823e-06 0.30
KLK1_HUMAN KLK1 Kallikrein-1 5.6e-06 0.30
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 6.557e-06 0.37
USP_DROME usp Protein ultraspiracle 6.739e-06 0.32
KIFC1_HUMAN KIFC1 Kinesin-like protein KIFC1 7.355e-06 0.29
GABT_RAT Abat 4-aminobutyrate aminotransferase, mitochondrial 9.96e-06 0.30

Latanoprostene_bunod

PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 2.002e-130 0.69
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 2.324e-109 0.69
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 3.22e-80 0.69
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 2.616e-76 0.69
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 2.116e-50 0.34
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 2.471e-27 0.34
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 8.67e-26 0.38
MGLL_RAT Mgll Monoglyceride lipase 1.176e-23 0.30
Q9NAW4_PLAFA Cysteine protease falcipain-3 2.07e-19 0.30
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 1.11e-16 0.29
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 1.388e-14 0.40
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 5.486e-13 0.49
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 8.103e-12 0.50
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 1.513e-11 0.34
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 8.313e-10 0.35
NAAA_HUMAN NAAA N-acylethanolamine-hydrolyzing acid amidase 2.547e-09 0.29
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 6.781e-09 0.50
TA2R_RAT Tbxa2r Thromboxane A2 receptor 1.536e-08 0.33
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 2.702e-06 0.35

Fruquintinib

PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 1.026e-78 0.50
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 9.559e-70 0.56
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 7.513e-61 0.55
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.119e-43 0.54
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 2.677e-40 0.51
EGFR_HUMAN EGFR Epidermal growth factor receptor 4.649e-37 0.49
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 2.121e-30 0.50
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 5.486e-29 0.47
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 1.781e-28 0.32
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 1.908e-28 0.44
PDE3B_HUMAN PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase B 4.447e-25 0.32
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 1.238e-22 0.34
TIE2_HUMAN TEK Angiopoietin-1 receptor 1.9e-20 0.55
AUKBA_XENLA aurkb-a Aurora kinase B-A 2.621e-19 0.31
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 7.189e-19 0.35
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 1.618e-17 0.50
MET_HUMAN MET Hepatocyte growth factor receptor 1.682e-17 0.51
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 1.813e-17 0.40
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 5.376e-17 0.47
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 1.11e-16 0.33
LCK_HUMAN LCK Tyrosine-protein kinase Lck 1.11e-16 0.48
PDE3A_HUMAN PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase A 1.11e-16 0.32
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 7.772e-16 0.52
C3SLB7_ECOLX glmU Bifunctional protein GlmU 4.398e-13 0.34
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 2.101e-12 0.36
FAK2_MOUSE Ptk2b Protein-tyrosine kinase 2-beta 4.995e-12 0.32
AURKB_HUMAN AURKB Aurora kinase B 5.774e-12 0.55
AURKA_HUMAN AURKA Aurora kinase A 6.638e-12 0.55
NEK11_HUMAN NEK11 Serine/threonine-protein kinase Nek11 1.723e-11 0.34
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.809e-11 0.38
CLK1_MOUSE Clk1 Dual specificity protein kinase CLK1 2.271e-11 0.34
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 5.975e-11 0.34
VGFR2_DANRE kdr Vascular endothelial growth factor receptor 2 7.173e-11 0.29
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 7.196e-11 0.32
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 7.721e-11 0.50
ATM_HUMAN ATM Serine-protein kinase ATM 1.912e-10 0.31
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 3.19e-10 0.34
STK4_HUMAN STK4 Serine/threonine-protein kinase 4 3.496e-10 0.34
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 5.768e-10 0.34
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 8.961e-10 0.34
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 1.46e-09 0.34
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 3.264e-09 0.34
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 4.388e-09 0.34
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 8.661e-09 0.38
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 1.015e-08 0.34
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 1.403e-08 0.38
A5H660_SCHMA HDAC8 Histone deacetylase 8 2.371e-08 0.30
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 2.61e-08 0.50
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 3.405e-08 0.32
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 6.293e-08 0.30
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 3.642e-07 0.44
GAK_HUMAN GAK Cyclin-G-associated kinase 4.67e-07 0.34
AURKC_HUMAN AURKC Aurora kinase C 5.24e-07 0.34
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 5.871e-07 0.34
FGFR2_HUMAN FGFR2 Fibroblast growth factor receptor 2 5.908e-07 0.40
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 1.331e-06 0.34
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 2.12e-06 0.50
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 2.648e-06 0.34
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 2.68e-06 0.35
PDE1B_HUMAN PDE1B Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B 3.237e-06 0.30
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 3.354e-06 0.36
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 4.225e-06 0.29
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 4.465e-06 0.34
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 4.635e-06 0.31
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 5.752e-06 0.28
LUCI_AQULA Luciferin 4-monooxygenase 5.99e-06 0.29
Q7T1G6_DANRE trpn1 Ion channel NompC 6.37e-06 0.35

Tucatinib

EGFR_HUMAN EGFR Epidermal growth factor receptor 1.333e-69 0.38
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 7.236e-66 0.41
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 8.516e-61 0.33
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 2.8e-47 0.33
ERBB2_RAT Erbb2 Receptor tyrosine-protein kinase erbB-2 3.533e-46 0.29
DUS2L_HUMAN DUS2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like 4.269e-37 0.29
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 1.396e-34 0.30
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 1.691e-32 0.32
EGFR_MOUSE Egfr Epidermal growth factor receptor 3.881e-28 0.34
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 7.711e-19 0.38
LUCI_RENRE Coelenterazine h 2-monooxygenase 3.331e-16 0.30
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 7.772e-16 0.34
HXK4_HUMAN GCK Hexokinase-4 7.369e-10 0.35
NCOA1_HUMAN NCOA1 Nuclear receptor coactivator 1 8.473e-10 0.35
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 5.41e-09 0.34
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 2.36e-08 0.29
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 2.396e-08 0.33
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 4.144e-07 0.31
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 6.126e-07 0.33
CD38_MOUSE Cd38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 1.879e-06 0.30
VP16_HHV11 Tegument protein VP16 3.276e-06 0.35
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 3.615e-06 0.28
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 3.951e-06 0.32

Amifampridine

AMO_PEA Primary amine oxidase 6.261e-50 0.32
KAT8_HUMAN KAT8 Histone acetyltransferase KAT8 1.237e-26 0.43
CP2A6_HUMAN CYP2A6 Cytochrome P450 2A6 1.596e-21 0.35
AOC1_HUMAN AOC1 Amiloride-sensitive amine oxidase [copper-containing] 4.25e-20 0.54
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 4.687e-10 0.36
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 6.745e-09 0.50
NFAC1_HUMAN NFATC1 Nuclear factor of activated T-cells, cytoplasmic 1 3.189e-08 0.29
PI51C_HUMAN PIP5K1C Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma 4.905e-07 0.29
PI4KA_HUMAN PI4KA Phosphatidylinositol 4-kinase alpha 5.537e-07 0.29
PTR1_LEIMA PTR1 Pteridine reductase 1 1.124e-06 0.45
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 6.289e-06 0.50

Treosulfan

ALDOA_RABIT ALDOA Fructose-bisphosphate aldolase A 2.227e-37 0.32
ALF_TRYBB ALD Fructose-bisphosphate aldolase, glycosomal 2.227e-37 0.32
DCOR_RAT Odc1 Ornithine decarboxylase 3.331e-08 0.32
6PGD_HUMAN PGD 6-phosphogluconate dehydrogenase, decarboxylating 5.192e-08 0.28

Daprodustat

EGLN1_HUMAN EGLN1 Egl nine homolog 1 1.15e-36 0.45
P4HA1_RAT P4ha1 Prolyl 4-hydroxylase subunit alpha-1 1.444e-23 0.29
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 5.296e-07 0.33
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 3.999e-06 0.31
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 4.984e-06 0.29

Vinflunine

Q25270_LEIDO beta-tubulin Beta-tubulin 3.213e-29 0.78
TRPM8_MOUSE Trpm8 Transient receptor potential cation channel subfamily M member 8 1.255e-18 0.33
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 1.313e-18 0.69
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.068e-07 0.78