Results of Job: search_f315e971-1c4b-4698-9dd6-7fc4109203c1

Query Target Key Target Name Description P-Value MaxTC

compound_1

KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 1.962e-237 0.74
AURKA_HUMAN AURKA Aurora kinase A 5.051e-191 0.74
EGFR_HUMAN EGFR Epidermal growth factor receptor 2.958e-103 0.51
AURKB_HUMAN AURKB Aurora kinase B 1.066e-101 0.62
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 3.521e-73 0.34
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 2.904e-67 0.40
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 6.44e-56 0.40
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 2.248e-55 0.36
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 4.14e-55 0.51
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 3.349e-51 0.37
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 9.189e-45 0.34
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.75e-44 0.43
DUS2L_HUMAN DUS2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like 1.353e-43 0.35
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 4.717e-43 0.40
SHH_MOUSE Shh Sonic hedgehog protein 6.655e-41 0.36
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 4.197e-39 0.34
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 2.93e-37 0.32
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 5.415e-37 0.36
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 1.847e-36 0.38
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 4.982e-36 0.35
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 4.539e-33 0.33
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 6.125e-33 0.44
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 5.051e-29 0.34
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 4.87e-28 0.32
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 1.086e-24 0.36
ENL_HUMAN MLLT1 Protein ENL 1.342e-24 0.30
AUKBA_XENLA aurkb-a Aurora kinase B-A 2.245e-21 0.34
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 9.314e-20 0.31
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 1.818e-19 0.30
RXFP1_HUMAN RXFP1 Relaxin receptor 1 7.342e-19 0.33
TPOR_HUMAN MPL Thrombopoietin receptor 2.647e-18 0.34
EPHB_MYCTO Epoxide hydrolase B 3.488e-18 0.29
CD38_MOUSE Cd38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 5.611e-18 0.37
GRM1_HUMAN GRM1 Metabotropic glutamate receptor 1 1.412e-17 0.37
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.415e-17 0.29
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 3.685e-17 0.30
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 1.11e-16 0.40
SMO_HUMAN SMO Smoothened homolog 1.221e-15 0.37
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 1.443e-15 0.37
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 2.776e-15 0.32
Q9SPL6_CICIN PPX1 Protoporphyrinogen oxidase 5.884e-15 0.28
Q9XQA6_POAAN psbA Photosystem II protein D1 5.884e-15 0.28
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 1.765e-14 0.35
UROK_HUMAN PLAU Urokinase-type plasminogen activator 2.354e-14 0.37
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 2.398e-14 0.34
TPA_HUMAN PLAT Tissue-type plasminogen activator 3.519e-14 0.37
NR1H4_HUMAN NR1H4 Bile acid receptor 3.986e-14 0.36
CTNB1_HUMAN CTNNB1 Catenin beta-1 3.113e-13 0.34
EGFR_MOUSE Egfr Epidermal growth factor receptor 3.505e-13 0.28
AOFB_RAT Maob Amine oxidase [flavin-containing] B 4.579e-13 0.35
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 7.008e-13 0.39
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 1.594e-12 0.32
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 1.81e-12 0.39
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 1.857e-12 0.32
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.283e-12 0.32
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 2.42e-12 0.32
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 6.512e-12 0.34
HDAC3_HUMAN HDAC3 Histone deacetylase 3 8.335e-12 0.41
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 8.488e-12 0.34
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.015e-11 0.36
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 1.099e-11 0.36
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 1.628e-11 0.29
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 9.055e-11 0.30
LCK_HUMAN LCK Tyrosine-protein kinase Lck 1.113e-10 0.35
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 1.272e-10 0.28
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 2.16e-10 0.37
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 3.278e-10 0.38
HDAC1_HUMAN HDAC1 Histone deacetylase 1 5.037e-10 0.41
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 7.674e-10 0.40
KCNQ2_RAT Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 9.835e-10 0.33
BTK_HUMAN BTK Tyrosine-protein kinase BTK 1.077e-09 0.35
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 1.314e-09 0.36
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 1.915e-09 0.32
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 1.984e-09 0.35
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 2.45e-09 0.44
HDAC6_HUMAN HDAC6 Histone deacetylase 6 2.711e-09 0.34
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 4.205e-09 0.35
PSBA_MARPO psbA Photosystem II protein D1 4.226e-09 0.28
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 5.51e-09 0.37
SCAF_HCMVA UL80 Capsid scaffolding protein 5.716e-09 0.32
HPSE_HUMAN HPSE Heparanase 1.478e-08 0.30
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 1.608e-08 0.38
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 2.015e-08 0.37
SENP7_HUMAN SENP7 Sentrin-specific protease 7 2.675e-08 0.35
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 3.166e-08 0.32
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 3.39e-08 0.35
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 4.163e-08 0.39
PRIO_SHEEP PRNP Major prion protein 5.845e-08 0.37
IL6_HUMAN IL6 Interleukin-6 1.276e-07 0.30
IKKB_HUMAN IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 1.81e-07 0.34
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 2.348e-07 0.29
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 2.811e-07 0.29
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 2.881e-07 0.30
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 4.707e-07 0.30
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 5.167e-07 0.34
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 5.643e-07 0.31
SHH_HUMAN SHH Sonic hedgehog protein 6.368e-07 0.31
GYRB_MYCSM gyrB DNA gyrase subunit B 6.457e-07 0.34
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.194e-06 0.37
PDPK1_HUMAN PDPK1 3-phosphoinositide-dependent protein kinase 1 1.241e-06 0.58
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 1.29e-06 0.39
INSR_HUMAN INSR Insulin receptor 1.405e-06 0.32
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 1.415e-06 0.39
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 1.663e-06 0.35
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 2.227e-06 0.32
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 2.382e-06 0.37
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 2.566e-06 0.35
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 2.707e-06 0.35
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 2.708e-06 0.30
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 3.365e-06 0.35
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 3.628e-06 0.35
CAH4_HUMAN CA4 Carbonic anhydrase 4 3.928e-06 0.32
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 4.068e-06 0.29
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 4.071e-06 0.30
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 5.282e-06 0.32
LYOX_HUMAN LOX Protein-lysine 6-oxidase 5.557e-06 0.29
PAG_BACAN pagA Protective antigen 6.113e-06 0.36
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 6.381e-06 0.35
LUCI_AQULA Luciferin 4-monooxygenase 6.502e-06 0.29
KCNQ3_HUMAN KCNQ3 Potassium voltage-gated channel subfamily KQT member 3 9.449e-06 0.31