Results of Job: search_f43704ad-8920-4bd7-b26b-14dc28f8cc17

Query Target Key Target Name Description P-Value MaxTC

Ritonavir

Q72874_9HIV1 pol Pol polyprotein 3.164e-141 1.00
Q9YQ12_9HIV1 protease Protease 1.272e-68 1.00
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 3.937e-30 1.00
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.22e-15 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 9.163e-06 1.00
THAS_HUMAN TBXAS1 Thromboxane-A synthase 0.03839 1.00
NK2R_HUMAN TACR2 Substance-K receptor 0.04852 1.00
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 0.1002 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.2687 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.9676 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 0.9982 1.00
O90781_9PLVG HIV-1 protease HIV-1 protease 2.51e-74 0.48
CPNS1_PIG CAPNS1 Calpain small subunit 1 1.892e-60 0.33
POL_HV1A2 gag-pol Gag-Pol polyprotein 6.898e-54 0.29
PEPA_PIG PGA Pepsin A 7.899e-46 0.38
CANX_CHICK Calpain-1 catalytic subunit 2.321e-45 0.36
PLM1_PLAFA Plasmepsin-1 2.676e-43 0.36
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 1.389e-41 0.36
PSA1_HUMAN PSMA1 Proteasome subunit alpha type-1 1.969e-41 0.34
PSA2_HUMAN PSMA2 Proteasome subunit alpha type-2 1.969e-41 0.34
PSA3_HUMAN PSMA3 Proteasome subunit alpha type-3 1.969e-41 0.34
PSA4_HUMAN PSMA4 Proteasome subunit alpha type-4 1.969e-41 0.34
PSA5_HUMAN PSMA5 Proteasome subunit alpha type-5 1.969e-41 0.34
PSA6_HUMAN PSMA6 Proteasome subunit alpha type-6 1.969e-41 0.34
PSA7_HUMAN PSMA7 Proteasome subunit alpha type-7 1.969e-41 0.34
PSB11_HUMAN PSMB11 Proteasome subunit beta type-11 1.969e-41 0.34
PSB3_HUMAN PSMB3 Proteasome subunit beta type-3 1.969e-41 0.34
PSB4_HUMAN PSMB4 Proteasome subunit beta type-4 1.969e-41 0.34
PSB6_HUMAN PSMB6 Proteasome subunit beta type-6 1.969e-41 0.34
PSB7_HUMAN PSMB7 Proteasome subunit beta type-7 1.969e-41 0.34
PSMA8_HUMAN PSMA8 Proteasome subunit alpha-type 8 1.969e-41 0.34
PAPA1_CARPA Papain 3.741e-40 0.31
PSB10_HUMAN PSMB10 Proteasome subunit beta type-10 4.21e-40 0.34
POLG_HRV14 Genome polyprotein 8.796e-36 0.28
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 6.316e-34 0.34
CATD_BOVIN CTSD Cathepsin D 6.812e-34 0.34
Q4U254_9ENTO protease Protease 1.057e-32 0.38
CATB_BOVIN CTSB Cathepsin B 3.266e-32 0.31
RENI_RAT Ren1 Renin 1.233e-31 0.36
CATD_HUMAN CTSD Cathepsin D 1.277e-31 0.38
PLM2_PLAFA Plasmepsin-2 2.53e-30 0.36
CASP9_HUMAN CASP9 Caspase-9 1.383e-29 0.32
Q3HTL5_PLAFA fp2B Falcipain 2B 3.907e-29 0.36
Q8I6Z5_PLAF7 Plasmepsin V 8.622e-29 0.33
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 1.41e-28 0.34
GP142_HUMAN GPR142 Probable G-protein coupled receptor 142 2.446e-28 0.34
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 3.179e-28 0.34
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 2.183e-27 0.34
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 1.733e-26 0.36
CATE_HUMAN CTSE Cathepsin E 3.118e-26 0.32
PTPRB_HUMAN PTPRB Receptor-type tyrosine-protein phosphatase beta 9.569e-26 0.34
PEPA1_PENJA Penicillopepsin-1 3.394e-25 0.28
PEPC_HUMAN PGC Gastricsin 1.046e-24 0.31
CATZ_RAT Ctsz Cathepsin Z 4.795e-23 0.28
Q9NBD4_PLAFA Cysteine protease falcipain-2 6.377e-23 0.28
KLK5_HUMAN KLK5 Kallikrein-5 1.873e-19 0.35
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 1.664e-18 0.29
CASP1_HUMAN CASP1 Caspase-1 1.961e-18 0.34
CATH_RAT Ctsh Pro-cathepsin H 7.277e-18 0.28
CATJ_RAT Ctsj Cathepsin J 7.277e-18 0.28
RENI_HUMAN REN Renin 8.346e-18 0.36
CATB_HUMAN CTSB Cathepsin B 4.441e-16 0.36
SCAF_HHV11 UL26 Capsid scaffolding protein 8.882e-16 0.31
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 1.776e-15 0.34
FFAR2_MOUSE Ffar2 Free fatty acid receptor 2 4.219e-15 0.29
CATC_RAT Ctsc Dipeptidyl peptidase 1 6.217e-15 0.28
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 4.33e-14 0.33
BACE1_HUMAN BACE1 Beta-secretase 1 1.351e-13 0.39
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 1.34e-11 0.32
THER_BACTH npr Thermolysin 2.183e-11 0.30
CYSP_TRYCR Cruzipain 3.028e-11 0.31
MCA2_TRYBB MCA2 Metacaspase 7.519e-11 0.32
CARP_RHICH Rhizopuspepsin 8.923e-11 0.34
P88142_9HIV2 pol Pol polyprotein 8.25e-10 0.28
CASPA_HUMAN CASP10 Caspase-10 9.181e-10 0.28
CASP1_MOUSE Casp1 Caspase-1 1.32e-09 0.32
CATK_HUMAN CTSK Cathepsin K 1.539e-09 0.33
CASP4_HUMAN CASP4 Caspase-4 1.686e-09 0.29
CASP7_HUMAN CASP7 Caspase-7 5.611e-09 0.32
CATL1_HUMAN CTSL Cathepsin L1 9.095e-09 0.36
APH1A_HUMAN APH1A Gamma-secretase subunit APH-1A 9.72e-09 0.39
APH1B_HUMAN APH1B Gamma-secretase subunit APH-1B 9.72e-09 0.39
NICA_HUMAN NCSTN Nicastrin 9.72e-09 0.39
PEN2_HUMAN PSENEN Gamma-secretase subunit PEN-2 9.802e-09 0.39
PSN2_HUMAN PSEN2 Presenilin-2 1.005e-08 0.39
CATL1_BOVIN CTSL Cathepsin L1 1.024e-08 0.30
CASP3_HUMAN CASP3 Caspase-3 1.457e-08 0.32
PSN1_HUMAN PSEN1 Presenilin-1 2.181e-08 0.39
R1A_SARS Replicase polyprotein 1a 2.332e-08 0.31
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 2.769e-08 0.36
SPP2A_HUMAN SPPL2A Signal peptide peptidase-like 2A 1.995e-07 0.29
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 3.953e-07 0.30
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 7.467e-07 0.32
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 1.829e-06 0.32
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 2.648e-06 0.29
R1AB_SARS rep Replicase polyprotein 1ab 2.696e-06 0.31
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 4.123e-06 0.32
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 5.756e-06 0.42
NK2R_MESAU TACR2 Substance-K receptor 7.903e-06 0.30

Levallorphan

OPRM_HUMAN OPRM1 Mu-type opioid receptor 6.96e-80 1.00
OPRM_RAT Oprm1 Mu-type opioid receptor 1.017e-39 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.06969 1.00
OPRD_HUMAN OPRD1 Delta-type opioid receptor 4.025e-99 0.86
F7HEV7_MACMU YTHDF2 G_PROTEIN_RECEP_F1_2 domain-containing protein 6.332e-96 0.59
H9FL65_MACMU OPRK1 Kappa-type opioid receptor 6.332e-96 0.59
OPRM_MACMU OPRM1 Mu-type opioid receptor 3.13e-85 0.59
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 5.087e-83 0.75
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 3.904e-77 0.86
OPRM_MOUSE Oprm1 Mu-type opioid receptor 2.881e-62 0.69
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 1.347e-60 0.42
OPRM_CAVPO OPRM1 Mu-type opioid receptor 2.942e-59 0.86
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 3.033e-52 0.69
OPRD_MOUSE Oprd1 Delta-type opioid receptor 2.226e-38 0.49
ZN664_CAVPO ZNF664 Zinc finger protein 664 7.287e-37 0.46
OPRM_BOVIN OPRM1 Mu-type opioid receptor 2.486e-36 0.38
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 1.379e-25 0.69
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 7.413e-23 0.59
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 9.009e-20 0.59
OPRD_RAT Oprd1 Delta-type opioid receptor 2.22e-16 0.46
ERG2_YEAST ERG2 C-8 sterol isomerase 2.471e-13 0.59
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2.181e-11 0.59
ACHA3_RAT Chrna3 Neuronal acetylcholine receptor subunit alpha-3 1.293e-09 0.52
ACHB4_RAT Chrnb4 Neuronal acetylcholine receptor subunit beta-4 1.366e-09 0.52
OPRK_RAT Oprk1 Kappa-type opioid receptor 2.109e-08 0.34
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 1.392e-06 0.46

Tridihexethyl

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.0001867 1.00
AMYP_RAT Amy2 Pancreatic alpha-amylase 4.87e-63 0.38
ACH10_HUMAN CHRNA10 Neuronal acetylcholine receptor subunit alpha-10 3.56e-37 0.29
ACHA9_HUMAN CHRNA9 Neuronal acetylcholine receptor subunit alpha-9 3.56e-37 0.29
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 1.78e-36 0.39
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.708e-28 0.57
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 1.163e-27 0.38
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 2.702e-25 0.57
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 8.788e-24 0.57
ABHDB_HUMAN ABHD11 Protein ABHD11 2.758e-19 0.31
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.779e-18 0.57
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 1.11e-16 0.38
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 5.551e-16 0.57
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 1.11e-15 0.30
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 3.456e-11 0.30
MEN1_HUMAN MEN1 Menin 3.466e-10 0.32
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 1.731e-06 0.30