Results of Job: search_f7bf8db8-b0f3-4f5f-9525-b3b7b99e490d

Query Target Key Target Name Description P-Value MaxTC

Tiagabine

SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 7.969e-282 1.00
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 3.49e-230 1.00
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 3.587e-212 1.00
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 7.516e-27 1.00
KEAP1_MOUSE Keap1 Kelch-like ECH-associated protein 1 6.705e-36 0.28
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 5.433e-23 0.44
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 1.873e-20 0.45
G3H407_CRIGR PROKR2 3.808e-18 0.34
DRD2_BOVIN DRD2 D(2) dopamine receptor 6.584e-14 0.33
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 9.96e-13 0.40
G3HIE5_CRIGR Prokineticin receptor 1 3.495e-12 0.31
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.425e-11 0.44
ERG_HUMAN ERG Transcriptional regulator ERG 7.541e-10 0.29
PDE8B_HUMAN PDE8B High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B 6.295e-09 0.33
PDE8A_HUMAN PDE8A High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A 9.077e-09 0.33
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 2.212e-08 0.34
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 3.231e-08 0.44
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 4.179e-08 0.28
GPBAR_MOUSE Gpbar1 G-protein coupled bile acid receptor 1 1.438e-07 0.29
ERG2_YEAST ERG2 C-8 sterol isomerase 1.823e-07 0.28
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 1.926e-07 0.35
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 2.285e-07 0.32
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2.079e-06 0.28

Sirolimus

FKB1A_MOUSE Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 1.48e-266 1.00
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 7.572e-102 1.00
FKB1B_HUMAN FKBP1B Peptidyl-prolyl cis-trans isomerase FKBP1B 4.237e-70 1.00
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 3.59e-28 1.00
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 1.214e-27 1.00
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 4.665e-11 1.00
IF4E_HUMAN EIF4E Eukaryotic translation initiation factor 4E 7.587e-06 1.00
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 0.07225 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.1247 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.9567 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.9676 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.9994 1.00
PP2BA_HUMAN PPP3CA Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform 1.433e-107 0.39
AT2A2_RAT Atp2a2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 4.449e-37 0.29
AT1A1_RAT Atp1a1 Sodium/potassium-transporting ATPase subunit alpha-1 7.193e-24 0.29
AT1A3_RAT Atp1a3 Sodium/potassium-transporting ATPase subunit alpha-3 4.959e-12 0.29
AT1A2_RAT Atp1a2 Sodium/potassium-transporting ATPase subunit alpha-2 6.023e-11 0.29
SF3B3_HUMAN SF3B3 Splicing factor 3B subunit 3 8.59e-11 0.39
FKBP4_HUMAN FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4 1.929e-07 0.40

Tacrolimus

PP2BA_HUMAN PPP3CA Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform 1.336e-224 1.00
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 1.986e-167 1.00
FKB1B_HUMAN FKBP1B Peptidyl-prolyl cis-trans isomerase FKBP1B 4.237e-70 1.00
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 1.214e-27 1.00
SF3B3_HUMAN SF3B3 Splicing factor 3B subunit 3 1.645e-26 1.00
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 4.665e-11 1.00
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 0.1887 1.00
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 0.4441 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.9567 1.00
FKB1A_MOUSE Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 4.245e-115 0.42
FKBP4_HUMAN FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4 1.665e-15 0.88
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 1.92e-11 0.39

Cocaine

SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 7.362e-217 1.00
Q9WTR4_RAT Slc6a2 Transporter 1.141e-166 1.00
SC6A3_BOVIN SLC6A3 Sodium-dependent dopamine transporter 4.199e-161 1.00
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 5.074e-104 1.00
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.228e-103 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 3.898e-89 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 7.941e-48 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 1.218e-38 1.00
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 4.781e-11 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.0002446 1.00
Q63380_RAT NET Transporter 0.0003039 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.005281 1.00
SC6A4_MACMU SLC6A4 Sodium-dependent serotonin transporter 2.807e-93 0.49
Q7JHP9_MACMU SLC6A3 Transporter 4.468e-93 0.49
Q8WSF8_APLCA Soluble acetylcholine receptor 8.543e-77 0.57
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 3.046e-60 0.43
ACHP_LYMST Acetylcholine-binding protein 1.078e-50 0.57
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 3.054e-43 0.56
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.132e-37 0.57
F1LNR9_RAT Slc6a2 Transporter 2.087e-36 0.30
GSTT1_RAT Gstt1 Glutathione S-transferase theta-1 1.377e-35 0.28
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 1.137e-33 0.52
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 4.414e-30 0.57
ACHA9_RAT Chrna9 Neuronal acetylcholine receptor subunit alpha-9 5.042e-29 0.32
Q8VH27_CAVPO GPM2 Muscarinic acetylcholine receptor 3.524e-25 0.52
ADA2A_PIG ADRA2A Alpha-2A adrenergic receptor 7.913e-25 0.31
5HT4R_MOUSE Htr4 5-hydroxytryptamine receptor 4 1.248e-24 0.30
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 1.332e-24 0.33
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 2.876e-24 0.38
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 7.321e-24 0.33
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 2.942e-22 0.39
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 4.695e-22 0.33
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 2.262e-20 0.35
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.22e-16 0.66
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 8.882e-16 0.66
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 1.998e-15 0.38
5HT3B_HUMAN HTR3B 5-hydroxytryptamine receptor 3B 3.442e-15 0.29
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 6.772e-15 0.66
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 7.216e-15 0.41
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 2.536e-13 0.39
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 2.313e-11 0.37
ITPR3_BOVIN ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 6.059e-11 0.35
VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 4.084e-10 0.29
Q8WMX0_BOVIN Muscarinic receptor M1 5.442e-10 0.38
ACHA7_MOUSE Chrna7 Neuronal acetylcholine receptor subunit alpha-7 1.109e-09 0.37
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.951e-09 0.34
OPRD_HUMAN OPRD1 Delta-type opioid receptor 3.372e-09 0.34
ITA5_HUMAN ITGA5 Integrin alpha-5 5.289e-09 0.47
PPM1B_HUMAN PPM1B Protein phosphatase 1B 1.111e-08 0.29
Q4QYD9_RAT Heat sensitive channel TRPV3 1.493e-08 0.28
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 1.582e-08 0.47
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 4.388e-08 0.38
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 5.16e-08 0.66
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 5.261e-08 0.40
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 9.446e-08 0.52
ELOV6_HUMAN ELOVL6 Elongation of very long chain fatty acids protein 6 1.33e-07 0.32
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 1.753e-07 0.47
ACHB2_RAT Chrnb2 Neuronal acetylcholine receptor subunit beta-2 2.532e-07 0.35
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 2.617e-07 0.28
ACHA4_RAT Chrna4 Neuronal acetylcholine receptor subunit alpha-4 3.92e-07 0.35
Q8AWE3_CHICK Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B 4.268e-07 0.29
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 4.369e-07 0.32
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 5.14e-07 0.37
BLA1_ECOLX bla Beta-lactamase SHV-1 6.149e-07 0.29
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 6.354e-07 0.29
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 6.854e-07 0.33
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 8.387e-07 0.47
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 9.656e-07 0.48
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 1.058e-06 0.40
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 1.216e-06 0.40
LEG9_HUMAN LGALS9 Galectin-9 1.359e-06 0.29
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 1.369e-06 0.42
OPRX_CAVPO OPRL1 Nociceptin receptor 1.507e-06 0.30
CHLE_HUMAN BCHE Cholinesterase 1.541e-06 0.39
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 2.14e-06 0.42
ACHA3_HUMAN CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 2.436e-06 0.47
ACHB4_RAT Chrnb4 Neuronal acetylcholine receptor subunit beta-4 2.81e-06 0.34
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 2.829e-06 0.42
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 2.989e-06 0.33
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 3.495e-06 0.31
OX1R_RAT Hcrtr1 Orexin receptor type 1 3.958e-06 0.29

Quinapril

ACE_HUMAN ACE Angiotensin-converting enzyme 4.17e-186 1.00
ACE_RABIT ACE Angiotensin-converting enzyme 2.633e-141 1.00
ACE_RAT Ace Angiotensin-converting enzyme 1.605e-123 0.70
ADAM9_HUMAN ADAM9 Disintegrin and metalloproteinase domain-containing protein 9 2.125e-102 0.43
OPRD_RAT Oprd1 Delta-type opioid receptor 4.15e-93 0.53
OPRD_MOUSE Oprd1 Delta-type opioid receptor 9.373e-89 0.49
OPRM_RAT Oprm1 Mu-type opioid receptor 2.493e-85 0.49
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 1.476e-74 0.41
AREG_HUMAN AREG Amphiregulin 1.652e-69 0.35
Q9NAW4_PLAFA Cysteine protease falcipain-3 5.486e-66 0.38
PRSS8_HUMAN PRSS8 Prostasin 2.881e-63 0.32
CTRB_BOVIN Chymotrypsinogen B 1.051e-62 0.34
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.232e-58 0.44
NEP_RABIT MME Neprilysin 8.483e-57 0.44
NEP_RAT Mme Neprilysin 2.419e-54 0.60
ACE_MOUSE Ace Angiotensin-converting enzyme 9.268e-54 0.56
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 7.123e-49 0.33
MMP3_HUMAN MMP3 Stromelysin-1 2.701e-47 0.43
PRO_HTL1A gag-pro Gag-Pro polyprotein 9.338e-47 0.32
XPP2_RAT Xpnpep2 Xaa-Pro aminopeptidase 2 1.872e-44 0.35
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 5.439e-40 0.34
CFTR_HUMAN CFTR Cystic fibrosis transmembrane conductance regulator 8.393e-40 0.40
Q95PM0_TRYBR rhodesain Cysteine protease 1.362e-39 0.34
GHRHR_RAT Ghrhr Growth hormone-releasing hormone receptor 2.946e-39 0.31
DPP4_MOUSE Dpp4 Dipeptidyl peptidase 4 1.094e-36 0.44
Q9Y006_PLAFA hap HAP protein 5.94e-36 0.28
BKRB1_RAT Bdkrb1 B1 bradykinin receptor 2.609e-35 0.33
OPRD_HUMAN OPRD1 Delta-type opioid receptor 5.062e-34 0.48
TPP2_RAT Tpp2 Tripeptidyl-peptidase 2 7.286e-33 0.33
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 3.651e-32 0.33
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 3.286e-31 0.38
BKRB2_RABIT BDKRB2 B2 bradykinin receptor 5.199e-31 0.34
NEP_HUMAN MME Neprilysin 6.874e-31 0.41
THER_BACTH npr Thermolysin 1.105e-29 0.42
XPP2_HUMAN XPNPEP2 Xaa-Pro aminopeptidase 2 4.681e-29 0.35
XPP1_HUMAN XPNPEP1 Xaa-Pro aminopeptidase 1 4.929e-29 0.35
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 8.208e-29 0.34
NR1D1_HUMAN NR1D1 Nuclear receptor subfamily 1 group D member 1 8.238e-29 0.41
BAD_HUMAN BAD Bcl2-associated agonist of cell death 3.695e-28 0.32
BRCA1_HUMAN BRCA1 Breast cancer type 1 susceptibility protein 3.074e-27 0.29
NEP_MOUSE Mme Neprilysin 1.777e-26 0.30
MMP1_HUMAN MMP1 Interstitial collagenase 2.66e-26 0.43
AGTR2_RAT Agtr2 Type-2 angiotensin II receptor 7.507e-26 0.48
Q9NBD4_PLAFA Cysteine protease falcipain-2 1.246e-25 0.32
CYSP_TRYCR Cruzipain 1.509e-25 0.34
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 5.318e-25 0.43
Q704V1_PSEAI blaGIM-1 GIM-1 protein 5.379e-25 0.31
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 9.245e-25 0.56
CATB_BOVIN CTSB Cathepsin B 1.488e-24 0.33
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 8.22e-24 0.31
E1BI31_BOVIN DPP9 Dipeptidyl peptidase 9 1.558e-23 0.38
MC4R_MOUSE Mc4r Melanocortin receptor 4 2.727e-23 0.40
MC3R_MOUSE Mc3r Melanocortin receptor 3 6.989e-23 0.40
MMP8_HUMAN MMP8 Neutrophil collagenase 3.321e-22 0.39
AMPL_HUMAN LAP3 Cytosol aminopeptidase 7.126e-22 0.31
AMP1_PLAFQ M1 family aminopeptidase 7.882e-22 0.34
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 1.801e-21 0.48
PPCE_MOUSE Prep Prolyl endopeptidase 6.124e-21 0.29
AMPN_HUMAN ANPEP Aminopeptidase N 1.568e-20 0.38
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 5.518e-20 0.34
CATK_HUMAN CTSK Cathepsin K 1.065e-19 0.36
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 1.507e-19 0.31
O31048_PORGN DPP IV Dipeptidyl peptidase IV 1.539e-19 0.38
MC5R_MOUSE Mc5r Melanocortin receptor 5 1.733e-19 0.40
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 6.863e-19 0.33
FNTB_RAT Fntb Protein farnesyltransferase subunit beta 3.244e-18 0.38
FNTA_RAT Fnta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 4.489e-18 0.38
CATL1_HUMAN CTSL Cathepsin L1 9.263e-18 0.35
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.087e-17 0.48
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 2.094e-17 0.40
LKHA4_CAVPO LTA4H Leukotriene A-4 hydrolase 1.11e-16 0.35
PPCE_HUMAN PREP Prolyl endopeptidase 2.22e-16 0.42
CATG_HUMAN CTSG Cathepsin G 1.11e-15 0.31
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.221e-15 0.30
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 1.443e-15 0.38
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 1.887e-15 0.30
CATB_HUMAN CTSB Cathepsin B 2.331e-15 0.34
A3EZI9_9HEPC NS3 Genome polyprotein 3.109e-15 0.36
Q9IP65_HCMV US28 G protein-coupled receptor 3.553e-15 0.29
MC4R_HUMAN MC4R Melanocortin receptor 4 5.773e-15 0.41
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 4.907e-14 0.32
CBPA1_HUMAN CPA1 Carboxypeptidase A1 6.051e-14 0.31
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 8.671e-14 0.43
PP2AA_BOVIN PPP2CA Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 1.203e-13 0.30
AMPB_RAT Rnpep Aminopeptidase B 2.056e-13 0.29
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 2.897e-13 0.32
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 2.948e-13 0.38
DPP8_HUMAN DPP8 Dipeptidyl peptidase 8 3.683e-13 0.38
BIRC2_HUMAN BIRC2 Baculoviral IAP repeat-containing protein 2 5.772e-13 0.32
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 6.347e-13 0.34
AMPN_PIG ANPEP Aminopeptidase N 8.092e-13 0.34
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 1.064e-12 0.31
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 1.064e-12 0.31
CCR10_MOUSE Ccr10 C-C chemokine receptor type 10 1.272e-12 0.34
PEPD_HUMAN PEPD Xaa-Pro dipeptidase 1.288e-12 0.31
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.813e-12 0.33
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 4.429e-12 0.31
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 7.237e-12 0.31
B4URF0_I33A0 Neuraminidase 1.006e-11 0.40
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 1.15e-11 0.28
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 1.34e-11 0.43
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 1.498e-11 0.31
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 1.526e-11 0.29
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 2.712e-11 0.30
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 3.317e-11 0.48
PPCE_BOVIN PREP Prolyl endopeptidase 4.265e-11 0.35
CASP1_MOUSE Casp1 Caspase-1 9.026e-11 0.30
US28_HCMVA US28 G-protein coupled receptor homolog US28 9.455e-11 0.29
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 1.811e-10 0.31
MMP25_HUMAN MMP25 Matrix metalloproteinase-25 4.159e-10 0.32
DPP9_HUMAN DPP9 Dipeptidyl peptidase 9 5.12e-10 0.38
MEP50_HUMAN WDR77 Methylosome protein 50 5.984e-10 0.33
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 6.339e-10 0.34
NANH_CLOPF nanH Sialidase 6.379e-10 0.38
MMP2_HUMAN MMP2 72 kDa type IV collagenase 6.881e-10 0.36
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 7.57e-10 0.33
NRAM_I34A1 Neuraminidase 8.429e-10 0.38
PEPA_PIG PGA Pepsin A 1.485e-09 0.30
NRAM_I77AB Neuraminidase 1.821e-09 0.31
PEPT1_DERPT DERP1 Peptidase 1 1.924e-09 0.30
BCL2_HUMAN BCL2 Apoptosis regulator Bcl-2 2.377e-09 0.37
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 3.44e-09 0.33
OPRK_RAT Oprk1 Kappa-type opioid receptor 3.727e-09 0.32
RENI_HUMAN REN Renin 4.32e-09 0.56
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 4.956e-09 0.37
ANF_HUMAN NPPA Natriuretic peptides A 5.398e-09 0.32
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 6.749e-09 0.34
HDAC8_HUMAN HDAC8 Histone deacetylase 8 7.259e-09 0.35
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 1.052e-08 0.33
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 1.073e-08 0.32
DLG4_HUMAN DLG4 Disks large homolog 4 1.29e-08 0.32
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 1.349e-08 0.29
DPP2_HUMAN DPP7 Dipeptidyl peptidase 2 1.626e-08 0.35
MC3R_HUMAN MC3R Melanocortin receptor 3 1.633e-08 0.33
VHL_HUMAN VHL von Hippel-Lindau disease tumor suppressor 1.649e-08 0.32
D2K2A8_9HEPC NS4A Non-structural protein 4A 1.926e-08 0.33
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 2.343e-08 0.33
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 2.848e-08 0.32
CBPA1_BOVIN CPA1 Carboxypeptidase A1 3.526e-08 0.30
NK1R_CAVPO TACR1 Substance-P receptor 4.148e-08 0.38
Q72874_9HIV1 pol Pol polyprotein 4.586e-08 0.33
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 8.655e-08 0.34
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.27e-07 0.33
SPP2A_HUMAN SPPL2A Signal peptide peptidase-like 2A 1.721e-07 0.29
CATS_HUMAN CTSS Cathepsin S 1.933e-07 0.36
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 2.496e-07 0.35
SCYD_MAGO7 SDH1 Scytalone dehydratase 2.717e-07 0.34
A5Z252_9INFA Neuraminidase 2.889e-07 0.30
Q6PRC7_IXORI Legumain-like protease 3.078e-07 0.30
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 3.146e-07 0.33
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 3.15e-07 0.32
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 3.15e-07 0.32
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 3.15e-07 0.32
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 3.15e-07 0.32
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 3.15e-07 0.32
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 3.15e-07 0.32
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 3.15e-07 0.32
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 3.15e-07 0.32
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 3.15e-07 0.32
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 3.15e-07 0.32
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 3.15e-07 0.32
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 3.15e-07 0.32
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 3.15e-07 0.32
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 3.15e-07 0.32
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 3.15e-07 0.32
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 3.15e-07 0.32
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 3.15e-07 0.32
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 3.15e-07 0.32
NK1R_RAT Tacr1 Substance-P receptor 3.68e-07 0.32
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 3.727e-07 0.29
S12A5_RAT Slc12a5 Solute carrier family 12 member 5 3.907e-07 0.29
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 3.997e-07 0.32
CTRA_BOVIN Chymotrypsinogen A 4.11e-07 0.30
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 4.642e-07 0.33
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 4.703e-07 0.32
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 6.013e-07 0.28
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 6.36e-07 0.28
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 6.792e-07 0.31
MMP12_HUMAN MMP12 Macrophage metalloelastase 7.124e-07 0.32
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.03e-06 0.34
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 1.069e-06 0.31
THRB_BOVIN F2 Prothrombin 1.097e-06 0.42
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.118e-06 0.42
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.199e-06 0.31
Q4U254_9ENTO protease Protease 1.239e-06 0.32
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 1.332e-06 0.40
CMA1_HUMAN CMA1 Chymase 1.34e-06 0.31
DPP4_RAT Dpp4 Dipeptidyl peptidase 4 1.454e-06 0.44
PLM2_PLAFA Plasmepsin-2 2.102e-06 0.29
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 2.369e-06 0.29
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 2.7e-06 0.30
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 2.79e-06 0.30
FNTA_HUMAN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 2.974e-06 0.39
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 3.559e-06 0.29
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 3.64e-06 0.29
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 3.873e-06 0.32
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 4.404e-06 0.33
PPCE_PIG PREP Prolyl endopeptidase 4.543e-06 0.33
NRAM_INBLE Neuraminidase 4.8e-06 0.38
THRB_HUMAN F2 Prothrombin 5.079e-06 0.32
NRAM_I33A0 Neuraminidase 5.335e-06 0.31
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 5.387e-06 0.32
GRAB_HUMAN GZMB Granzyme B 5.455e-06 0.30
CASP1_HUMAN CASP1 Caspase-1 5.96e-06 0.30
TRY1_BOVIN Cationic trypsin 7.425e-06 0.33

Buprenorphine

OPRK_HUMAN OPRK1 Kappa-type opioid receptor 4.964e-184 1.00
OPRD_HUMAN OPRD1 Delta-type opioid receptor 2.517e-173 1.00
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 1.209e-165 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 6.422e-150 1.00
OPRM_MOUSE Oprm1 Mu-type opioid receptor 5.186e-144 1.00
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.62e-120 1.00
OPRD_RAT Oprd1 Delta-type opioid receptor 7.233e-111 1.00
OPRM_RAT Oprm1 Mu-type opioid receptor 1.548e-110 1.00
OPRX_HUMAN OPRL1 Nociceptin receptor 4.376e-29 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9999 1.00
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 2.727e-123 0.53
OPRM_BOVIN OPRM1 Mu-type opioid receptor 1.419e-111 0.88
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.629e-103 0.53
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.455e-63 0.88
TLR4_MOUSE Tlr4 Toll-like receptor 4 8.185e-38 0.39
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 1.451e-37 0.59
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 4.202e-20 0.30
OPRX_CAVPO OPRL1 Nociceptin receptor 6.292e-07 0.32

Phenprocoumon

VKOR1_RAT Vkorc1 Vitamin K epoxide reductase complex subunit 1 7.78e-183 1.00
Q72874_9HIV1 pol Pol polyprotein 1.11e-16 1.00
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 2.856e-114 0.72
NQO1_RAT Nqo1 NAD(P)H dehydrogenase [quinone] 1 1.164e-65 0.53
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 1.258e-52 0.34
CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 1.415e-46 0.32
VKOR1_BOVIN VKORC1 Vitamin K epoxide reductase complex subunit 1 2.246e-39 0.35
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 5.581e-29 0.36
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 5.827e-26 0.32
PCSK7_HUMAN PCSK7 Proprotein convertase subtilisin/kexin type 7 1.917e-23 0.53
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 2.308e-23 0.55
P89582_9HIV2 pol Integrase 5.144e-19 0.42
Q39829_SOYBN Lipoxygenase 8.29e-19 0.30
HST2_YEAST HST2 NAD-dependent protein deacetylase HST2 1.039e-18 0.30
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.11e-16 0.33
Q49PX0_9POXV N1L N1L 2.22e-16 0.30
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 1.21e-14 0.32
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 2.288e-13 0.32
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 1.295e-12 0.34
Q4U254_9ENTO protease Protease 2.146e-12 0.58
AOFB_RAT Maob Amine oxidase [flavin-containing] B 9.645e-12 0.36
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 1.809e-11 0.36
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 8.458e-11 0.35
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 3.905e-10 0.36
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 7.892e-10 0.42
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 2.988e-09 0.29
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 1.083e-08 0.31
CALM1_HUMAN CALM1 Calmodulin-1 1.709e-08 0.30
Q7ZJM1_9HIV1 pol Integrase 2.508e-08 0.43
STXA_SHIDY stxA Shiga toxin subunit A 3.985e-08 0.29
1433G_HUMAN YWHAG 14-3-3 protein gamma 5.363e-08 0.28
Q17SB2_PLAFA Plasmepsin 4 6.82e-08 0.31
DOPO_HUMAN DBH Dopamine beta-hydroxylase 8.352e-08 0.29
GPR55_HUMAN GPR55 G-protein coupled receptor 55 3.033e-07 0.36
GPR18_HUMAN GPR18 N-arachidonyl glycine receptor 4.349e-07 0.33
NK3R_HUMAN TACR3 Neuromedin-K receptor 6.236e-07 0.33
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 8.682e-07 0.34
PB1_HUMAN PBRM1 Protein polybromo-1 4.084e-06 0.29
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 4.848e-06 0.37
NR1H4_MOUSE Nr1h4 Bile acid receptor 5.16e-06 0.28
CBPA1_BOVIN CPA1 Carboxypeptidase A1 6.747e-06 0.32
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 7.911e-06 0.36
MIF_HUMAN MIF Macrophage migration inhibitory factor 8.933e-06 0.31
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 9.113e-06 0.39

Perphenazine

PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 1.947e-177 1.00
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 8.026e-34 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 4.388e-33 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 3.331e-16 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.0001023 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.005023 1.00
PRIO_MOUSE Prnp Major prion protein 6.607e-74 0.59
TYTR_TRYCR TPR Trypanothione reductase 5.703e-62 0.59
EBPL_HUMAN EBPL Emopamil-binding protein-like 2.598e-52 0.57
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 4.089e-51 0.72
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 5.756e-50 0.32
LYSC1_RAT Lyz1 Lysozyme C-1 6.897e-46 0.57
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 5.849e-43 0.80
CALM_BOVIN CALM Calmodulin 4.006e-41 0.59
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 3.753e-40 0.59
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 7.179e-38 0.46
DRD4_RAT Drd4 D(4) dopamine receptor 2.268e-36 0.33
BGLR_RAT Gusb Beta-glucuronidase 2.175e-35 0.57
HNMT_RAT Hnmt Histamine N-methyltransferase 9.77e-33 0.30
CALM1_HUMAN CALM1 Calmodulin-1 8.829e-31 0.59
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 3.105e-30 0.80
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 2.011e-28 0.59
HRH1_HUMAN HRH1 Histamine H1 receptor 9.623e-28 0.80
DRD3_HUMAN DRD3 D(3) dopamine receptor 3.202e-27 0.80
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.051e-26 0.80
DRD2_RAT Drd2 D(2) dopamine receptor 5.233e-26 0.59
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 3.736e-25 0.80
FA8_HUMAN F8 Coagulation factor VIII 9.719e-24 0.29
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.599e-23 0.80
DRD5_HUMAN DRD5 D(1B) dopamine receptor 2.108e-23 0.72
DRD3_RAT Drd3 D(3) dopamine receptor 1.14e-22 0.46
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.176e-22 0.37
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 1.004e-21 0.42
HRH3_CAVPO HRH3 Histamine H3 receptor 7.663e-21 0.33
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 7.339e-20 0.80
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 1.28e-19 0.41
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 8.023e-19 0.31
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 2.749e-18 0.42
DRD1_RAT Drd1 D(1A) dopamine receptor 9.803e-18 0.59
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.405e-17 0.80
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.983e-17 0.80
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 2.115e-17 0.80
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 2.171e-17 0.80
HRH1_RAT Hrh1 Histamine H1 receptor 1.232e-14 0.43
SL9A3_RAT Slc9a3 Sodium/hydrogen exchanger 3 1.332e-14 0.33
ERG2_YEAST ERG2 C-8 sterol isomerase 2.753e-14 0.57
HRP1_PLAFA Histidine-rich protein PFHRP-II 3.131e-14 0.29
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.072e-13 0.80
CHLE_HUMAN BCHE Cholinesterase 1.086e-13 0.43
CHLE_HORSE BCHE Cholinesterase 3.149e-13 0.55
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.477e-12 0.39
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 2.039e-12 0.35
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 3.384e-12 0.57
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 3.935e-12 0.33
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 4.293e-12 0.80
TYTR_TRYBB TPR Trypanothione reductase 4.914e-12 0.39
US28_HCMVA US28 G-protein coupled receptor homolog US28 9.395e-12 0.32
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.539e-11 0.80
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 2.996e-11 0.80
NOX1_HUMAN NOX1 NADPH oxidase 1 3.92e-11 0.35
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 9.183e-11 0.34
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 1.055e-10 0.59
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.175e-10 0.80
HRH2_HUMAN HRH2 Histamine H2 receptor 6.765e-10 0.72
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.254e-09 0.37
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 2.415e-09 0.35
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 3.556e-09 0.80
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 4.009e-09 0.80
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 4.612e-09 0.80
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 8.799e-09 0.32
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.234e-08 0.80
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.357e-08 0.59
DRD1_PIG DRD1 D(1A) dopamine receptor 2.039e-08 0.31
WDR48_HUMAN WDR48 WD repeat-containing protein 48 4.305e-08 0.57
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 5.953e-08 0.57
HRH3_HUMAN HRH3 Histamine H3 receptor 6.367e-08 0.52
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 1.982e-07 0.31
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 2.173e-07 0.80
PRIO_HUMAN PRNP Major prion protein 4.805e-07 0.59
AAPK2_HUMAN PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 6.339e-07 0.30
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.012e-06 0.39
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 1.142e-06 0.80
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.383e-06 0.31
AAKG1_HUMAN PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 2.025e-06 0.30
ACES_ELEEL ache Acetylcholinesterase 2.036e-06 0.40
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 4.21e-06 0.30
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 6.182e-06 0.43
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 8.622e-06 0.29
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 9.519e-06 0.30
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 9.9e-06 0.39

Salmeterol

ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 9.031e-153 1.00
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 1.202e-125 1.00
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 9.407e-124 1.00
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 2.637e-65 1.00
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 6.957e-27 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.747e-05 1.00
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 1.202e-104 0.49
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 5.372e-64 0.31
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 9.47e-61 0.35
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 1.28e-48 0.40
ADRB3_MOUSE Adrb3 Beta-3 adrenergic receptor 1.51e-42 0.34
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 6.395e-29 0.37
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 9.187e-21 0.34
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 5.635e-20 0.45
HEXA_HUMAN HEXA Beta-hexosaminidase subunit alpha 8.357e-20 0.32
LIPL_HUMAN LPL Lipoprotein lipase 8.29e-19 0.30
SYFA_HAEIN pheS Phenylalanine--tRNA ligase alpha subunit 2.139e-18 0.29
SYFA_STRPN pheS Phenylalanine--tRNA ligase alpha subunit 2.139e-18 0.29
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 1.324e-17 0.31
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 9.104e-15 0.55
EGFR_MOUSE Egfr Epidermal growth factor receptor 2.232e-14 0.32
PERM_HUMAN MPO Myeloperoxidase 2.621e-13 0.42
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 6.397e-13 0.32
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 1.559e-12 0.29
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 3.509e-12 0.65
TYTR_TRYCR TPR Trypanothione reductase 1.091e-11 0.31
CBS_HUMAN CBS Cystathionine beta-synthase 1.42e-11 0.31
Q6RY99_RAT Tetraspanin 7.655e-11 0.29
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 7.039e-10 0.31
ASAH1_HUMAN ASAH1 Acid ceramidase 3.483e-09 0.30
LIPE_MOUSE Lipg Endothelial lipase 4.655e-09 0.33
AMP1_PLAFQ M1 family aminopeptidase 3.191e-08 0.30
DRD2_HUMAN DRD2 D(2) dopamine receptor 4.894e-08 0.49
NAAA_HUMAN NAAA N-acylethanolamine-hydrolyzing acid amidase 1.104e-07 0.30
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 1.552e-07 0.32
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 2.377e-07 0.41
POLG_CXB3N Genome polyprotein 6.162e-07 0.30
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 6.39e-07 0.28
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.13e-06 0.31
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 1.507e-06 0.30
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 7.597e-06 0.36
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 7.705e-06 0.28
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 7.857e-06 0.41
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 9.231e-06 0.41

Granisetron

5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 1.503e-149 1.00
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 2.982e-70 1.00
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 7.085e-55 1.00
5HT3B_HUMAN HTR3B 5-hydroxytryptamine receptor 3B 1.089e-50 1.00
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 3.331e-16 1.00
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.22e-15 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.004329 1.00
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 1.19e-90 0.55
5HT4R_MOUSE Htr4 5-hydroxytryptamine receptor 4 1.254e-78 0.50
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 2.242e-78 0.33
BCAT2_HUMAN BCAT2 Branched-chain-amino-acid aminotransferase, mitochondrial 1.033e-49 0.35
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 2.077e-48 0.34
ACHA7_MACMU CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 1.921e-39 0.31
Q8VBU5_MOUSE Pde4b Phosphodiesterase 5.403e-33 0.32
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 6.461e-21 0.37
SC6A3_BOVIN SLC6A3 Sodium-dependent dopamine transporter 1.248e-19 0.31
CFAD_HUMAN CFD Complement factor D 6.736e-19 0.36
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 5.011e-18 0.32
PDE7A_HUMAN PDE7A High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A 4.441e-16 0.32
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 8.882e-16 0.50
CNR1_HUMAN CNR1 Cannabinoid receptor 1 2.887e-15 0.39
DRD3_RAT Drd3 D(3) dopamine receptor 7.216e-15 0.42
BCAT1_HUMAN BCAT1 Branched-chain-amino-acid aminotransferase, cytosolic 8.66e-15 0.32
CNR2_HUMAN CNR2 Cannabinoid receptor 2 1.343e-13 0.35
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.786e-13 0.41
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 1.315e-12 0.31
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.768e-12 0.33
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 7.881e-12 0.52
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.19e-11 0.37
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.802e-11 0.37
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 2.606e-11 0.31
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 3.22e-11 0.34
PER2_HUMAN PER2 Period circadian protein homolog 2 1.039e-10 0.31
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.03e-10 0.30
CNR2_RAT Cnr2 Cannabinoid receptor 2 4.065e-10 0.32
DRD2_RAT Drd2 D(2) dopamine receptor 1.033e-09 0.42
CRFR2_HUMAN CRHR2 Corticotropin-releasing factor receptor 2 1.476e-09 0.29
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.816e-09 0.37
ACHA7_MOUSE Chrna7 Neuronal acetylcholine receptor subunit alpha-7 5.304e-09 0.34
CNR1_RAT Cnr1 Cannabinoid receptor 1 6.426e-09 0.36
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 6.577e-09 0.33
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 6.935e-09 0.35
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 1.906e-08 0.30
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 2.333e-08 0.38
MK08_RAT Mapk8 Mitogen-activated protein kinase 8 5.431e-08 0.28
GRM5_HUMAN GRM5 Metabotropic glutamate receptor 5 6.234e-08 0.37
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 6.816e-08 0.29
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.43e-07 0.37
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 1.593e-07 0.33
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 1.621e-07 0.32
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.812e-07 0.30
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 2.645e-07 0.28
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 3.666e-07 0.30
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 4.396e-07 0.29
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 5.286e-07 0.43
PANC_MYCTU panC Pantothenate synthetase 1.111e-06 0.34
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 1.13e-06 0.31
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.402e-06 0.36
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.691e-06 0.36
ACHP_LYMST Acetylcholine-binding protein 1.984e-06 0.34
MK03_MOUSE Mapk3 Mitogen-activated protein kinase 3 3.175e-06 0.29
ELNE_HUMAN ELANE Neutrophil elastase 4.685e-06 0.35
CCNA2_HUMAN CCNA2 Cyclin-A2 6.256e-06 0.32
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 6.504e-06 0.34
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 8.741e-06 0.52
MK01_MOUSE Mapk1 Mitogen-activated protein kinase 1 9.419e-06 0.31

Meclofenamic_acid

AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 8.603e-120 1.00
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 1.6e-57 1.00
FABPI_HUMAN FABP2 Fatty acid-binding protein, intestinal 1.089e-50 1.00
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 8.384e-43 1.00
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 1.328e-39 1.00
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.078e-36 1.00
TTHY_HUMAN TTR Transthyretin 4.975e-27 1.00
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 4.208e-19 1.00
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 5.74e-11 1.00
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 6.58e-06 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.00137 1.00
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 0.2231 1.00
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 8.802e-86 0.40
IL8_HUMAN CXCL8 Interleukin-8 1.663e-63 0.68
ENTP1_RAT Entpd1 Ectonucleoside triphosphate diphosphohydrolase 1 1.921e-39 0.31
AAKG2_HUMAN PRKAG2 5'-AMP-activated protein kinase subunit gamma-2 2.095e-36 0.29
TFDP2_HUMAN TFDP2 Transcription factor Dp-2 2.095e-36 0.29
Q8S3J0_BROTE ALS Acetolactate synthase 1.609e-35 0.28
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 3.285e-35 0.36
G2YM83_BOTF4 Cytochrome b-c1 complex subunit Rieske, mitochondrial 6.921e-33 0.32
FABH_STRP3 fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.67e-30 0.30
USP_DROME usp Protein ultraspiracle 1.847e-25 0.31
ECR_BOMMO EcR Ecdysone receptor 9.226e-25 0.33
FABH_STAAM fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.962e-24 0.30
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 5.139e-24 0.31
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 9.153e-24 0.40
AAKG3_HUMAN PRKAG3 5'-AMP-activated protein kinase subunit gamma-3 1.926e-23 0.29
Q38C41_TRYB2 Phosphotransferase 4.905e-23 0.31
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 2.877e-22 0.51
CCR2_MOUSE Ccr2 C-C chemokine receptor type 2 9.863e-22 0.37
Q8MWR1_SPOFR USP Ultraspiracle protein 2.178e-21 0.31
Q8MWR2_SPOFR EcR Ecdysteroid receptor 2.178e-21 0.31
J7HAW4_RAPRA Acetolactate synthase 6.118e-21 0.30
ECR_DROME EcR Ecdysone receptor 6.856e-21 0.31
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 1.436e-20 0.29
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 9.479e-20 0.30
PYGL_RAT Pygl Glycogen phosphorylase, liver form 6.571e-19 0.29
AAKB2_HUMAN PRKAB2 5'-AMP-activated protein kinase subunit beta-2 3.615e-18 0.29
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 4.441e-16 0.31
STXA_SHIDY stxA Shiga toxin subunit A 1.11e-15 0.29
ACES_TETCF ache Acetylcholinesterase 7.661e-15 0.54
RPGF4_HUMAN RAPGEF4 Rap guanine nucleotide exchange factor 4 1.088e-14 0.35
SORT_HUMAN SORT1 Sortilin 1.765e-14 0.35
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 2.254e-14 0.31
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 2.909e-14 0.33
NR4A1_HUMAN NR4A1 Nuclear receptor subfamily 4 group A member 1 3.364e-14 0.40
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 4.841e-14 0.30
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 5.507e-14 0.30
CXCR2_HUMAN CXCR2 C-X-C chemokine receptor type 2 1.193e-13 0.34
Q9NBA7_PLAFA Cysteine protease falcipain-3 1.391e-13 0.37
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.583e-13 0.36
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 2.738e-13 0.40
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 1.761e-12 0.31
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 2.371e-12 0.32
E3UJZ5_SPOLI Ecdysone receptor 3.634e-12 0.33
Q9AQH7_STAAU dnaC Replicative DNA helicase 5.743e-12 0.29
KMO_MOUSE Kmo Kynurenine 3-monooxygenase 7.616e-12 0.29
IF4E_HUMAN EIF4E Eukaryotic translation initiation factor 4E 8.314e-12 0.33
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 5.162e-11 0.33
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 6.193e-11 0.43
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.634e-10 0.30
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 1.915e-10 0.35
EST1_RABIT Liver carboxylesterase 1 2.977e-10 0.34
O31272_9GAMM imiS Beta-lactamase 2.98e-10 0.32
MENB_MYCTU menB 1,4-dihydroxy-2-naphthoyl-CoA synthase 3.484e-10 0.30
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 3.573e-10 0.36
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 4.155e-10 0.35
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 5.428e-10 0.33
ENPP3_HUMAN ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 5.888e-10 0.31
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 1.364e-09 0.54
HIPK2_HUMAN HIPK2 Homeodomain-interacting protein kinase 2 2.371e-08 0.40
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 2.384e-08 0.35
DAPK3_HUMAN DAPK3 Death-associated protein kinase 3 2.678e-08 0.36
A5H660_SCHMA HDAC8 Histone deacetylase 8 2.874e-08 0.30
P2RX2_RAT P2rx2 P2X purinoceptor 2 3.657e-08 0.33
ST17A_HUMAN STK17A Serine/threonine-protein kinase 17A 4.529e-08 0.36
P2RX7_RAT P2rx7 P2X purinoceptor 7 4.811e-08 0.33
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 7.636e-08 0.45
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 1.124e-07 0.31
KC1A_HUMAN CSNK1A1 Casein kinase I isoform alpha 1.171e-07 0.35
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 1.24e-07 0.42
O39930_9HEPC NS5b RNA-directed RNA polymerase 1.638e-07 0.32
METC_ECOLI metC Cystathionine beta-lyase MetC 2.362e-07 0.29
BAD_HUMAN BAD Bcl2-associated agonist of cell death 2.521e-07 0.30
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 2.577e-07 0.34
PTPRG_HUMAN PTPRG Receptor-type tyrosine-protein phosphatase gamma 3.409e-07 0.33
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 3.878e-07 0.33
DYRK4_HUMAN DYRK4 Dual specificity tyrosine-phosphorylation-regulated kinase 4 4.163e-07 0.35
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 7.06e-07 0.43
PA21B_HUMAN PLA2G1B Phospholipase A2 7.403e-07 0.59
AAPK2_HUMAN PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 9.377e-07 0.29
MATK_HUMAN MATK Megakaryocyte-associated tyrosine-protein kinase 1.148e-06 0.35
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 1.37e-06 0.32
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 1.577e-06 0.35
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 1.64e-06 0.35
AGP1_YEAST AGP1 General amino acid permease AGP1 1.716e-06 0.32
RET4_HUMAN RBP4 Retinol-binding protein 4 1.904e-06 0.30
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 2.026e-06 0.59
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 2.326e-06 0.35
AAKG1_HUMAN PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 2.907e-06 0.29
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 3.495e-06 0.31
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 3.563e-06 0.28
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 3.798e-06 0.75
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 3.964e-06 0.31
FEN1_HUMAN FEN1 Flap endonuclease 1 4.1e-06 0.34
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 5.094e-06 0.32
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 5.483e-06 0.30
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 5.853e-06 0.35
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 6.326e-06 0.35
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 7.384e-06 0.40
CXCR1_HUMAN CXCR1 C-X-C chemokine receptor type 1 9.712e-06 0.43

Ritodrine

ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 2.452e-119 1.00
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 3.486e-107 1.00
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 4.102e-30 1.00
GALR3_HUMAN GALR3 Galanin receptor type 3 0.0001565 1.00
H9TVJ1_CHISP TyR1 1.499e-57 0.37
ACER2_HUMAN ACER2 Alkaline ceramidase 2 6.694e-38 0.30
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 2.553e-31 0.59
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 4.22e-30 0.45
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 2.381e-25 0.59
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 9.762e-23 0.53
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 4.405e-21 0.32
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 3.629e-19 0.38
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 2.22e-16 0.58
GLI1_HUMAN GLI1 Zinc finger protein GLI1 6.661e-16 0.30
IL1B_HUMAN IL1B Interleukin-1 beta 2.665e-15 0.29
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 1.565e-14 0.32
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 4.672e-13 0.51
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 2.274e-12 0.39
EZRI_HUMAN EZR Ezrin 3.82e-12 0.30
HD_HUMAN HTT Huntingtin 2.782e-11 0.31
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 3.866e-10 0.59
ESR2_HUMAN ESR2 Estrogen receptor beta 6.178e-10 0.44
TAT_HV1H2 tat Protein Tat 6.32e-10 0.29
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 7.421e-10 0.32
ESR1_HUMAN ESR1 Estrogen receptor 3.209e-09 0.44
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 2.757e-08 0.38
ESR2_RAT Esr2 Estrogen receptor beta 4.304e-08 0.34
NEP_RABIT MME Neprilysin 8.259e-08 0.31
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 1.876e-07 0.59
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 3.192e-07 0.38
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 3.273e-07 0.49
OPRM_RAT Oprm1 Mu-type opioid receptor 3.615e-07 0.35
TYRO_HUMAN TYR Tyrosinase 4.266e-07 0.33
ACE_HUMAN ACE Angiotensin-converting enzyme 8.273e-07 0.30
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.075e-06 0.32
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 1.638e-06 0.30
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 2.83e-06 0.49
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.849e-06 0.29
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 4.286e-06 0.38
CBPA1_BOVIN CPA1 Carboxypeptidase A1 5.141e-06 0.31
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 7.992e-06 0.38

Dinoprostone

PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 4.267e-115 1.00
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 2.85e-105 1.00
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 4.646e-87 1.00
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 2.175e-80 1.00
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 5.712e-77 1.00
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 2.674e-47 1.00
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 3.924e-45 1.00
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 1.726e-37 1.00
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 1.912e-33 1.00
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.735e-32 1.00
PI2R_HUMAN PTGIR Prostacyclin receptor 1.963e-30 1.00
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 2.122e-22 1.00
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 2.988e-12 1.00
PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 6.048e-144 0.67
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 3.446e-110 0.73
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 1.455e-109 0.72
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 1.37e-106 0.72
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 8.758e-70 0.67
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 2.885e-69 0.35
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 1.104e-41 0.72
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 1.137e-40 0.67
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 3.579e-36 0.67
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 1.514e-29 0.41
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 1.14e-28 0.29
IL6RB_HUMAN IL6ST Interleukin-6 receptor subunit beta 5.698e-23 0.29
CNR1_RAT Cnr1 Cannabinoid receptor 1 2.629e-18 0.58
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 5.76e-18 0.28
TA2R_RAT Tbxa2r Thromboxane A2 receptor 2.27e-17 0.61
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 1.477e-14 0.35
LOX15_PIG ALOX15 Arachidonate 15-lipoxygenase 6.362e-14 0.31
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 2.359e-13 0.32
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 6.464e-12 0.29
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.203e-11 0.39
MGLL_RAT Mgll Monoglyceride lipase 4.396e-11 0.32
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 1.194e-10 0.37
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 2.137e-10 0.38
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.164e-08 0.32
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 1.561e-08 0.47
Q6UB75_PIG Group VII phospholipase A2 1.612e-07 0.31
GPR18_HUMAN GPR18 N-arachidonyl glycine receptor 2.65e-07 0.34
GLCM_MOUSE Gba Lysosomal acid glucosylceramidase 3.35e-07 0.32
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 1.272e-06 0.29
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.751e-06 0.32
MPIP2_MOUSE Cdc25b M-phase inducer phosphatase 2 4.184e-06 0.30
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 5.02e-06 0.29
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 6.13e-06 0.31

Terbutaline

ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 6.307e-109 1.00
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 2.329e-31 1.00
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 1.088e-57 0.47
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 3.89e-50 0.60
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 1.704e-39 0.40
G3HDX1_CRIGR Alpha-1B adrenergic receptor 2.157e-22 0.43
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 3.775e-22 0.35
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 2.955e-20 0.41
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 6.661e-16 0.35
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 1.593e-12 0.40
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 1.261e-11 0.37
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 1.436e-10 0.60
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 9.182e-07 0.31
Q8WS26_TRYCR Farnesyl diphosphate synthase 9.904e-06 0.34

Levorphanol

OPRD_HUMAN OPRD1 Delta-type opioid receptor 1.91e-101 1.00
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 6.577e-84 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.63e-83 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.871e-82 1.00
OPRM_MOUSE Oprm1 Mu-type opioid receptor 1.404e-79 1.00
OPRM_CAVPO OPRM1 Mu-type opioid receptor 2.987e-65 1.00
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 1.32e-42 1.00
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 6.499e-36 1.00
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 2.207e-06 1.00
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 0.001681 1.00
F7HEV7_MACMU YTHDF2 G_PROTEIN_RECEP_F1_2 domain-containing protein 8.719e-91 0.42
H9FL65_MACMU OPRK1 Kappa-type opioid receptor 8.719e-91 0.42
OPRM_MACMU OPRM1 Mu-type opioid receptor 1.141e-80 0.42
OPRM_BOVIN OPRM1 Mu-type opioid receptor 1.525e-49 0.51
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.033e-47 0.56
OPRM_RAT Oprm1 Mu-type opioid receptor 7.669e-43 0.69
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 3.009e-40 0.41
OPRX_CAVPO OPRL1 Nociceptin receptor 2.727e-32 0.37
ZN664_CAVPO ZNF664 Zinc finger protein 664 6.285e-31 0.38
ACHB3_RAT Chrnb3 Neuronal acetylcholine receptor subunit beta-3 4.087e-30 0.38
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 4.008e-21 0.71
ACHA6_RAT Chrna6 Neuronal acetylcholine receptor subunit alpha-6 5.194e-19 0.38
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.332e-18 0.30
OPRD_RAT Oprd1 Delta-type opioid receptor 1.11e-16 0.56
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 2.22e-16 0.71
ACHB4_MOUSE Chrnb4 Neuronal acetylcholine receptor subunit beta-4 2.367e-13 0.30
ACHB2_MOUSE Chrnb2 Neuronal acetylcholine receptor subunit beta-2 1.686e-12 0.30
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 4.251e-12 0.30
ACHA9_RAT Chrna9 Neuronal acetylcholine receptor subunit alpha-9 6.352e-11 0.35
ERG2_YEAST ERG2 C-8 sterol isomerase 3.247e-10 0.41
ACHB2_RAT Chrnb2 Neuronal acetylcholine receptor subunit beta-2 9.282e-10 0.44
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.379e-09 0.30
ACHA4_RAT Chrna4 Neuronal acetylcholine receptor subunit alpha-4 1.643e-09 0.44
ACHA3_RAT Chrna3 Neuronal acetylcholine receptor subunit alpha-3 1.676e-09 0.51
ACHB4_RAT Chrnb4 Neuronal acetylcholine receptor subunit beta-4 1.769e-09 0.51
ESR1_MOUSE Esr1 Estrogen receptor 1.91e-09 0.30
ESR2_MOUSE Esr2 Estrogen receptor beta 1.91e-09 0.30
DRD5_HUMAN DRD5 D(1B) dopamine receptor 2.136e-09 0.33
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 9.659e-09 0.41
Q690N0_BOVIN PGR Progesterone receptor 2.661e-07 0.30
OPRK_RAT Oprk1 Kappa-type opioid receptor 2.71e-07 0.42
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 2.837e-07 0.38
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 3.053e-07 0.30
SHBG_HUMAN SHBG Sex hormone-binding globulin 7.861e-07 0.32
ACHA3_HUMAN CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 8.467e-07 0.38
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 1.324e-06 0.43
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.548e-06 0.33
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.876e-06 0.30
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 2.511e-06 0.30

Prednisolone

CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 7.433e-98 1.00
GCR_HUMAN NR3C1 Glucocorticoid receptor 6.556e-53 1.00
GCR_RAT Nr3c1 Glucocorticoid receptor 1.475e-50 1.00
GCR_MOUSE Nr3c1 Glucocorticoid receptor 3.804e-49 1.00
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 6.19e-39 1.00
GLNA_HUMAN GLUL Glutamine synthetase 3.937e-30 1.00
IL6_HUMAN IL6 Interleukin-6 7.773e-24 1.00
MCR_HUMAN NR3C2 Mineralocorticoid receptor 1.017e-07 1.00
PRGR_HUMAN PGR Progesterone receptor 1.981e-05 1.00
ANDR_HUMAN AR Androgen receptor 0.0004242 1.00
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 0.004722 1.00
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 0.5587 1.00
ATTY_RAT Tat Tyrosine aminotransferase 5.593e-96 0.36
Q690N0_BOVIN PGR Progesterone receptor 5.073e-73 0.57
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.804e-47 0.69
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 6.807e-46 0.41
CP19A_HUMAN CYP19A1 Aromatase 1.985e-37 0.47
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 5.859e-25 0.41
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 6.788e-24 0.41
F1Q298_CANLF NR3C1 Glucocorticoid receptor 3.817e-23 0.28
GCR_PIG NR3C1 Glucocorticoid receptor 3.817e-23 0.28
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 1.523e-18 0.29
NOS2_RAT Nos2 Nitric oxide synthase, inducible 3.442e-15 0.33
PRGR_RAT Pgr Progesterone receptor 3.442e-15 0.33
ANDR_RAT Ar Androgen receptor 1.898e-14 0.57
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.087e-14 0.41
PRGR_RABIT PGR Progesterone receptor 1.854e-13 0.35
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 4.013e-13 0.36
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.077e-10 0.41
ERG2_YEAST ERG2 C-8 sterol isomerase 4.421e-08 0.31
PPO2_AGABI PPO2 Polyphenol oxidase 2 9.4e-08 0.52
ANDR_MOUSE Ar Androgen receptor 1.093e-07 0.31
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.003e-06 0.40
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.366e-06 0.30
MCR_RAT Nr3c2 Mineralocorticoid receptor 2.092e-06 0.39
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 2.418e-06 0.34

Risedronic_acid

Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 7.365e-97 1.00
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 5.493e-87 1.00
Q8WS26_TRYCR Farnesyl diphosphate synthase 2.22e-15 1.00
Q197X6_TOXGO FPPS Farnesyl diphosphate synthase 1.001e-11 1.00
GGPPS_YEAST BTS1 Geranylgeranyl pyrophosphate synthase 2.859e-101 0.50
ISPA_ECOLI ispA Farnesyl diphosphate synthase 1.462e-67 0.42
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 5.992e-57 0.49
Q8MTZ4_9TRYP PPase1 Vacuolar-type proton translocating pyrophosphatase 1 4.313e-43 0.53
ACHA5_RAT Chrna5 Neuronal acetylcholine receptor subunit alpha-5 3.56e-37 0.29
Q8ST54_TRYCR HK Phosphotransferase 1.507e-34 0.64
GGPPS_HUMAN GGPS1 Geranylgeranyl pyrophosphate synthase 5.209e-34 0.50
THAS_HUMAN TBXAS1 Thromboxane-A synthase 2.863e-26 0.41
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 1.713e-25 0.42
ISPH_AQUAE ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 5.063e-24 0.47
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 2.366e-20 0.44
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 8.93e-20 0.35
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 1.464e-19 0.44
ACHP_LYMST Acetylcholine-binding protein 1.595e-19 0.38
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 2.477e-19 0.33
CLPP_STAA8 clpP ATP-dependent Clp protease proteolytic subunit 4.11e-19 0.30
CP2A6_HUMAN CYP2A6 Cytochrome P450 2A6 1.11e-16 0.33
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 6.051e-14 0.33
BT3A1_HUMAN BTN3A1 Butyrophilin subfamily 3 member A1 1.87e-13 0.37
Q05BA5_MOUSE Ncoa3 Nuclear receptor coactivator 1.108e-12 0.31
AMPL_PIG LAP3 Cytosol aminopeptidase 1.244e-12 0.38
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 2.691e-12 0.34
PNPH_RAT Pnp Purine nucleoside phosphorylase 4.098e-12 0.31
ACHA6_MOUSE Chrna6 Neuronal acetylcholine receptor subunit alpha-6 4.437e-12 0.33
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 8.302e-12 0.29
T1QYY3_9HIV1 int Integrase 8.327e-12 0.32
PPO1_AGABI PPO1 Polyphenol oxidase 1 1.05e-11 0.37
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 2.245e-11 0.31
DXR_ECOLI dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2.596e-11 0.59
THAS_RAT Tbxas1 Thromboxane-A synthase 4.165e-11 0.30
DXR_MYCTU dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 7.116e-11 0.35
KCNN4_HUMAN KCNN4 Intermediate conductance calcium-activated potassium channel protein 4 1.118e-10 0.33
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 1.346e-10 0.32
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 1.998e-10 0.46
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 2.312e-10 0.30
CNOT7_HUMAN CNOT7 CCR4-NOT transcription complex subunit 7 3.547e-10 0.37
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 9.824e-10 0.33
IMPA1_BOVIN IMPA1 Inositol monophosphatase 1 1.036e-09 0.33
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 2.338e-09 0.30
ACHA7_MOUSE Chrna7 Neuronal acetylcholine receptor subunit alpha-7 1.075e-08 0.33
ACHB2_RAT Chrnb2 Neuronal acetylcholine receptor subunit beta-2 9.908e-08 0.37
G6PC_HUMAN G6PC Glucose-6-phosphatase 1.238e-07 0.30
ACHA4_RAT Chrna4 Neuronal acetylcholine receptor subunit alpha-4 1.569e-07 0.37
AMPL_HUMAN LAP3 Cytosol aminopeptidase 1.722e-07 0.29
GRM2_HUMAN GRM2 Metabotropic glutamate receptor 2 3.703e-07 0.31
CP19A_RAT Cyp19a1 Aromatase 4.365e-07 0.33
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 9.67e-07 0.37
Q3Y5H1_9GAMC 3C-like protease 1.575e-06 0.28
STABP_HUMAN STAMBP STAM-binding protein 2.536e-06 0.32
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 4.231e-06 0.37
AMPN_HUMAN ANPEP Aminopeptidase N 4.377e-06 0.38
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 4.436e-06 0.32
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 4.934e-06 0.38
R1AB_SARS rep Replicase polyprotein 1ab 7.385e-06 0.29
CASP5_HUMAN CASP5 Caspase-5 7.953e-06 0.28

Eprosartan

AGTRB_RAT Agtr1b Type-1B angiotensin II receptor 5.008e-95 1.00
AGTR1_HUMAN AGTR1 Type-1 angiotensin II receptor 8.903e-75 1.00
AGTR2_RAT Agtr2 Type-2 angiotensin II receptor 1.552e-40 1.00
AGTRA_RAT Agtr1 Type-1A angiotensin II receptor 9.439e-60 0.48
AGTR1_RABIT AGTR1 Type-1 angiotensin II receptor 1.339e-59 0.65
AGTR1_BOVIN AGTR1 Type-1 angiotensin II receptor 3.01e-44 0.37
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 3.103e-21 0.30
A8K2H7_HUMAN C3AR1 Complement component 3a receptor 1, isoform CRA_a 1.187e-17 0.34
GP142_HUMAN GPR142 Probable G-protein coupled receptor 142 1.732e-14 0.31
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 4.804e-13 0.47
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 1.806e-11 0.31
RARB_HUMAN RARB Retinoic acid receptor beta 4.877e-11 0.36
TLR7_HUMAN TLR7 Toll-like receptor 7 6.971e-11 0.33
DOPO_RAT Dbh Dopamine beta-hydroxylase 9.106e-10 0.33
BLA1_STEMA Metallo-beta-lactamase L1 type 3 2.206e-09 0.30
MK08_RAT Mapk8 Mitogen-activated protein kinase 8 5.431e-08 0.28
BRS3_MOUSE Brs3 Bombesin receptor subtype-3 1.818e-07 0.29
ETHR_MYCTU ethR HTH-type transcriptional regulator EthR 5.389e-07 0.31
AGTR1_CAVPO AGTR1 Type-1 angiotensin II receptor 7.359e-07 0.35
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 8.338e-07 0.30
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 8.275e-06 0.29

Etacrynic_acid

GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 1.883e-88 1.00
GSTP1_HUMAN GSTP1 Glutathione S-transferase P 2.38e-51 1.00
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 0.02748 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.4056 1.00
PA2GX_MOUSE Pla2g10 Group 10 secretory phospholipase A2 2.186e-50 0.31
PA2GE_MOUSE Pla2g2e Group IIE secretory phospholipase A2 8.425e-45 0.31
PA2G5_MOUSE Pla2g5 Calcium-dependent phospholipase A2 1.5e-42 0.31
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 8.071e-42 0.41
PA21B_MOUSE Pla2g1b Phospholipase A2 1.437e-40 0.31
PA2GE_HUMAN PLA2G2E Group IIE secretory phospholipase A2 1.437e-40 0.31
PA2GA_MOUSE Pla2g2a Phospholipase A2, membrane associated 8.289e-39 0.31
PD2R2_MOUSE Ptgdr2 Prostaglandin D2 receptor 2 1.164e-33 0.35
PA2G5_HUMAN PLA2G5 Calcium-dependent phospholipase A2 2.394e-30 0.31
PA21B_HUMAN PLA2G1B Phospholipase A2 1.544e-27 0.32
PD2R2_RAT Ptgdr2 Prostaglandin D2 receptor 2 1.62e-24 0.30
PA2GD_MOUSE Pla2g2d Group IID secretory phospholipase A2 3.502e-24 0.31
PA2GF_HUMAN PLA2G2F Group IIF secretory phospholipase A2 1.024e-18 0.31
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 1.11e-16 0.31
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 6.55e-15 0.31
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 1.288e-14 0.37
PA2GF_MOUSE Pla2g2f Group IIF secretory phospholipase A2 1.102e-13 0.30
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 1.37e-13 0.31
PA21B_PIG PLA2G1B Phospholipase A2, major isoenzyme 1.573e-13 0.31
AK1A1_PIG AKR1A1 Aldo-keto reductase family 1 member A1 1.562e-12 0.31
CD69_HUMAN CD69 Early activation antigen CD69 3.325e-12 0.30
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 2.372e-09 0.41
POLG_DEN2P Genome polyprotein 1.258e-07 0.33
PPARD_MOUSE Ppard Peroxisome proliferator-activated receptor delta 3.265e-07 0.34
Q56D28_CAVPO CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells 4.359e-07 0.30
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 5.766e-06 0.36

Penicillamine

DAPE_HAEIN dapE Succinyl-diaminopimelate desuccinylase 2.714e-79 1.00
Q5HMD9_STAEQ murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 2.155e-45 0.29
AAA1_RAT Slc7a10 Asc-type amino acid transporter 1 2.281e-40 0.32
LEU3_THET8 leuB 3-isopropylmalate dehydrogenase 3.875e-36 0.29
AMPN_ECOLI pepN Aminopeptidase N 9.677e-35 0.28
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 5.348e-26 0.30
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 1.11e-16 0.32
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 2.22e-16 0.38
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 1.188e-14 0.33
BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 4.041e-14 0.29
GLN1B_ECOLI glnA Glutamine synthetase 6.108e-13 0.28
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 5.571e-12 0.29
CBPA1_BOVIN CPA1 Carboxypeptidase A1 1.984e-11 0.36
AMPB_HUMAN RNPEP Aminopeptidase B 1.105e-10 0.29
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 3.485e-10 0.37
GRIK2_HUMAN GRIK2 Glutamate receptor ionotropic, kainate 2 4.275e-09 0.33
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 1.849e-07 0.29
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 4.596e-07 0.37
GRIK3_HUMAN GRIK3 Glutamate receptor ionotropic, kainate 3 7.538e-07 0.30
GRM6_RAT Grm6 Metabotropic glutamate receptor 6 3.933e-06 0.30
GRIK5_HUMAN GRIK5 Glutamate receptor ionotropic, kainate 5 5.303e-06 0.30

Amantadine

M2_I000F M Matrix protein 2 1.444e-77 1.00
M2_I72A8 M Matrix protein 2 6.586e-52 1.00
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 2.207e-06 1.00
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 0.001681 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.5521 1.00
Q20MD5_I72A8 M2 Matrix protein 2 7.938e-18 0.39
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 4.947e-07 0.41
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 1.057e-06 0.41

Quinidine

KCND2_RAT Kcnd2 Potassium voltage-gated channel subfamily D member 2 5.121e-61 1.00
S22A2_MOUSE Slc22a2 Solute carrier family 22 member 2 5.121e-61 1.00
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 6.524e-44 1.00
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 6.524e-44 1.00
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 4.875e-41 1.00
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 9.712e-23 1.00
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 3.331e-16 1.00
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.016e-09 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.249e-07 1.00
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.851e-06 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.0002896 1.00
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 0.02632 1.00
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 0.07391 1.00
CHLE_HORSE BCHE Cholinesterase 0.2573 1.00
CHLE_HUMAN BCHE Cholinesterase 0.2814 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.7175 1.00
GYRA_STAAU gyrA DNA gyrase subunit A 5.287e-71 0.45
GYRB_STAAU gyrB DNA gyrase subunit B 3.299e-44 0.45
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 6.252e-27 0.38
GYRB_MYCSM gyrB DNA gyrase subunit B 2.344e-11 0.31
O97467_PLAFA ht1 Hexose transporter 1 1.153e-09 0.41
PDE3B_HUMAN PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase B 1.088e-08 0.31
PDE3A_HUMAN PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase A 8.282e-06 0.31

Flurandrenolide

Q690N0_BOVIN PGR Progesterone receptor 4.561e-56 1.00
GCR_HUMAN NR3C1 Glucocorticoid receptor 3.855e-18 1.00
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.1e-52 0.45
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 8.682e-42 0.38
GCR_MOUSE Nr3c1 Glucocorticoid receptor 2.961e-30 0.45
GCR_RAT Nr3c1 Glucocorticoid receptor 8.81e-23 0.43
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.437e-21 0.45
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.22e-16 0.38
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 3.331e-16 0.38
CP19A_HUMAN CYP19A1 Aromatase 1.568e-11 0.41
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.087e-10 0.34
GLNA_HUMAN GLUL Glutamine synthetase 1.087e-10 0.34
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 1.006e-08 0.34
IL6_HUMAN IL6 Interleukin-6 1.507e-08 0.34
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 4.947e-08 0.38
MCR_RAT Nr3c2 Mineralocorticoid receptor 5.101e-06 0.36

Clomifene

EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 4.017e-50 1.00
ERG2_YEAST ERG2 C-8 sterol isomerase 9.77e-41 1.00
ESR1_HUMAN ESR1 Estrogen receptor 3.554e-27 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.477e-09 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 2.837e-07 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 8.051e-07 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 8.462e-07 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 5.564e-06 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.882e-05 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 3.742e-05 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 0.000319 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.0007651 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.001102 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 0.001429 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.003316 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 0.01164 1.00
NK2R_HUMAN TACR2 Substance-K receptor 0.01566 1.00
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 0.02775 1.00
DNAB_MYCTU dnaB Replicative DNA helicase 0.1236 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.1387 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.1837 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.337 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.3913 1.00
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 0.4317 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.4764 1.00
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 0.4821 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 0.5402 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.6994 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.7089 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 0.9639 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.9861 1.00
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 2.933e-122 0.62
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 1.669e-101 0.46
AMYP_RAT Amy2 Pancreatic alpha-amylase 6.797e-56 0.38
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 3.534e-55 0.38
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 8.304e-50 0.46
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 1.136e-48 0.77
ACH10_HUMAN CHRNA10 Neuronal acetylcholine receptor subunit alpha-10 1.356e-39 0.31
ACHA9_HUMAN CHRNA9 Neuronal acetylcholine receptor subunit alpha-9 1.356e-39 0.31
SAT1_HUMAN SAT1 Diamine acetyltransferase 1 2.85e-39 0.31
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 2.345e-35 0.39
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 2.65e-35 0.34
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 2.241e-32 0.54
ACRO_PIG ACR Acrosin 2.275e-30 0.37
Q8WMX0_BOVIN Muscarinic receptor M1 2.109e-28 0.38
MYT1_HUMAN MYT1 Myelin transcription factor 1 6.442e-26 0.32
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 1.035e-25 0.57
NORA_STAAU norA Quinolone resistance protein NorA 5.433e-23 0.42
IKKB_MOUSE Ikbkb Inhibitor of nuclear factor kappa-B kinase subunit beta 6.987e-23 0.34
SRC_MOUSE Src Neuronal proto-oncogene tyrosine-protein kinase Src 2.04e-21 0.35
CP26B_HUMAN CYP26B1 Cytochrome P450 26B1 5.426e-20 0.30
CHLE_HORSE BCHE Cholinesterase 8.882e-16 0.43
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 2.509e-14 0.31
ACES_ELEEL ache Acetylcholinesterase 8.482e-14 0.40
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 2.986e-13 0.29
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 3.039e-13 0.42
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.255e-13 0.33
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 4.619e-13 0.31
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 8.57e-13 0.38
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 8.92e-13 0.54
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.68e-12 0.31
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 1.818e-12 0.32
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 2.394e-12 0.32
S100B_HUMAN S100B Protein S100-B 1.182e-10 0.31
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 2.328e-10 0.45
RARB_HUMAN RARB Retinoic acid receptor beta 4.143e-10 0.37
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 4.256e-10 0.31
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 4.644e-10 0.31
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 6.468e-10 0.31
LSS_HUMAN LSS Lanosterol synthase 1.007e-09 0.38
PA24A_HUMAN PLA2G4A Cytosolic phospholipase A2 1.091e-09 0.33
ACES_HUMAN ACHE Acetylcholinesterase 2.037e-09 0.55
ESR2_HUMAN ESR2 Estrogen receptor beta 2.113e-09 0.43
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 2.22e-09 0.39
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 3.249e-09 0.37
CP19A_HUMAN CYP19A1 Aromatase 4.666e-09 0.47
ALK_HUMAN ALK ALK tyrosine kinase receptor 1.093e-08 0.40
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 1.752e-08 0.32
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.985e-08 0.31
RARA_HUMAN RARA Retinoic acid receptor alpha 4.118e-08 0.37
RARG_HUMAN RARG Retinoic acid receptor gamma 9.785e-08 0.37
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 1.837e-07 0.32
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 6.778e-07 0.31
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 7.138e-07 0.32
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 7.39e-07 0.45
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 7.859e-07 0.44
CHLE_HUMAN BCHE Cholinesterase 9.619e-07 0.39
BMP4_HUMAN BMP4 Bone morphogenetic protein 4 1.268e-06 0.34
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.482e-06 0.29
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 2.139e-06 0.38
CDKA1_HUMAN CDK2AP1 Cyclin-dependent kinase 2-associated protein 1 2.409e-06 0.29
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 2.746e-06 0.32
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 2.823e-06 0.34
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 4.047e-06 0.37
DYR_CHICK DHFR Dihydrofolate reductase 4.601e-06 0.29
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 4.8e-06 0.31
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 4.906e-06 0.30
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 4.913e-06 0.32
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 5.595e-06 0.31
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 7.045e-06 0.31

Flupentixol

KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 7.922e-47 1.00
WDR48_HUMAN WDR48 WD repeat-containing protein 48 9.818e-12 1.00
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 1.582e-11 1.00
DRD1_RAT Drd1 D(1A) dopamine receptor 4.99e-09 1.00
DRD1_BOVIN DRD1 D(1A) dopamine receptor 2.207e-06 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.0001858 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.06134 1.00
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 2.246e-71 0.57
LYSC1_RAT Lyz1 Lysozyme C-1 2.774e-36 0.45
BGLR_RAT Gusb Beta-glucuronidase 5.083e-28 0.45
EBPL_HUMAN EBPL Emopamil-binding protein-like 5.083e-28 0.45
CALM_BOVIN CALM Calmodulin 2.22e-16 0.45
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 1.898e-14 0.31
CALM1_HUMAN CALM1 Calmodulin-1 2.14e-12 0.45
LYPA1_HUMAN LYPLA1 Acyl-protein thioesterase 1 5.106e-12 0.32
DRD5_HUMAN DRD5 D(1B) dopamine receptor 4.891e-10 0.57
ERG2_YEAST ERG2 C-8 sterol isomerase 9.473e-10 0.45
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 1.543e-09 0.30
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2.396e-08 0.45
HRH1_HUMAN HRH1 Histamine H1 receptor 2.383e-06 0.57
STE24_YEAST STE24 CAAX prenyl protease 1 2.585e-06 0.37
DRD2_RAT Drd2 D(2) dopamine receptor 2.679e-06 0.45

Cycrimine

ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 9.818e-46 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.001e-42 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 5.777e-39 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 9.801e-26 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 2.684e-25 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 7.818e-20 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 7.625e-12 1.00
HRH1_RAT Hrh1 Histamine H1 receptor 1.281e-06 1.00
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 1.091e-89 0.39
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 3.259e-74 0.40
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.311e-58 0.36
AMYP_RAT Amy2 Pancreatic alpha-amylase 4.53e-57 0.33
ABHDB_HUMAN ABHD11 Protein ABHD11 6.795e-57 0.33
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 5.348e-55 0.50
HRH3_HUMAN HRH3 Histamine H3 receptor 1.264e-53 0.39
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 3.021e-49 0.35
MEN1_HUMAN MEN1 Menin 1.691e-47 0.46
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 3.218e-45 0.41
DGLB_MOUSE Daglb Sn1-specific diacylglycerol lipase beta 2.533e-43 0.36
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 7.365e-43 0.43
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.733e-42 0.42
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 3.028e-39 0.35
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 1.01e-38 0.39
NPSR1_RAT Npsr1 Neuropeptide S receptor 1.381e-38 0.31
HRH3_MOUSE Hrh3 Histamine H3 receptor 4.085e-38 0.38
ABHD6_HUMAN ABHD6 Monoacylglycerol lipase ABHD6 1.358e-31 0.36
HNMT_RAT Hnmt Histamine N-methyltransferase 1.753e-29 0.33
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 2.098e-29 0.39
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 2.306e-29 0.52
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 7.118e-29 0.36
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 6.688e-28 0.40
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 9.257e-27 0.42
NPSR1_HUMAN NPSR1 Neuropeptide S receptor 1.133e-26 0.36
Q8WMX0_BOVIN Muscarinic receptor M1 2.148e-24 0.30
LYPA2_HUMAN LYPLA2 Acyl-protein thioesterase 2 1.087e-23 0.31
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 8.954e-23 0.34
LYPA1_HUMAN LYPLA1 Acyl-protein thioesterase 1 1.73e-21 0.31
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 4.338e-21 0.35
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.304e-20 0.56
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 1.443e-17 0.43
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 3.774e-17 0.33
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 1.11e-16 0.36
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 1.11e-16 0.32
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 9.548e-15 0.40
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 2.598e-14 0.32
LMBL3_HUMAN L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 3.275e-14 0.31
HRH3_RAT Hrh3 Histamine H3 receptor 8.071e-14 0.37
HRH1_HUMAN HRH1 Histamine H1 receptor 1.079e-13 0.44
TYTR_TRYBB TPR Trypanothione reductase 4.239e-13 0.32
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 1.249e-12 0.36
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.722e-12 0.30
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 2.513e-12 0.36
TERT_HUMAN TERT Telomerase reverse transcriptase 2.922e-12 0.33
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 4.605e-12 0.35
VACHT_RAT Slc18a3 Vesicular acetylcholine transporter 8.624e-12 0.33
CALM_BOVIN CALM Calmodulin 2.119e-11 0.31
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.551e-11 0.34
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 9.019e-11 0.31
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 3.841e-10 0.37
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 5.162e-10 0.29
HRH1_CAVPO HRH1 Histamine H1 receptor 5.581e-10 0.38
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 9.417e-10 0.42
PPCE_BOVIN PREP Prolyl endopeptidase 1.076e-09 0.30
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 1.117e-09 0.44
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 2.533e-09 0.29
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 2.681e-09 0.40
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 4.864e-09 0.28
ANM8_HUMAN PRMT8 Protein arginine N-methyltransferase 8 5.529e-09 0.32
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.822e-08 0.32
DPO1_THEAQ polA DNA polymerase I, thermostable 3.921e-08 0.33
ESR2_HUMAN ESR2 Estrogen receptor beta 8.033e-08 0.32
HRH2_HUMAN HRH2 Histamine H2 receptor 1.249e-07 0.32
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 1.346e-07 0.30
ESR1_HUMAN ESR1 Estrogen receptor 1.427e-07 0.33
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 2.643e-07 0.34
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 3.393e-07 0.37
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 4.513e-07 0.32
OPRX_HUMAN OPRL1 Nociceptin receptor 5.254e-07 0.33
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 1.684e-06 0.29
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 1.955e-06 0.31
Q63380_RAT NET Transporter 2.019e-06 0.33
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 3.168e-06 0.28
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 3.426e-06 0.31
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 3.669e-06 0.39
ACES_MOUSE Ache Acetylcholinesterase 3.702e-06 0.35
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 3.82e-06 0.38
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 4.618e-06 0.32
ACHP_LYMST Acetylcholine-binding protein 5.32e-06 0.32
DRD3_HUMAN DRD3 D(3) dopamine receptor 6.095e-06 0.56
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 6.522e-06 0.30
HRH3_CAVPO HRH3 Histamine H3 receptor 7.767e-06 0.36
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 7.804e-06 0.38

Repaglinide

ABCC8_HUMAN ABCC8 ATP-binding cassette sub-family C member 8 4.185e-40 1.00
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.785e-14 1.00
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 8.337e-90 0.42
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 1.319e-81 0.41
MC4R_HUMAN MC4R Melanocortin receptor 4 5.855e-81 0.44
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 1.846e-60 0.39
HCN1_HUMAN HCN1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 6.864e-53 0.33
TPH1_HUMAN TPH1 Tryptophan 5-hydroxylase 1 5.32e-50 0.40
HCN4_HUMAN HCN4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 9.896e-50 0.33
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 1.97e-46 0.31
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 8.786e-42 0.31
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 8.786e-42 0.31
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 8.786e-42 0.31
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 8.786e-42 0.31
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 8.786e-42 0.31
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 8.786e-42 0.31
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 8.786e-42 0.31
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 8.786e-42 0.31
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 8.786e-42 0.31
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 8.786e-42 0.31
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 8.786e-42 0.31
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 8.786e-42 0.31
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 8.786e-42 0.31
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 8.786e-42 0.31
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 8.786e-42 0.31
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 8.786e-42 0.31
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 8.786e-42 0.31
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 8.786e-42 0.31
PHHY_PSEFL pobA p-hydroxybenzoate hydroxylase 2.269e-41 0.33
HCN2_HUMAN HCN2 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 2.276e-38 0.30
HCN3_HUMAN HCN3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 2.276e-38 0.30
D4ADR1_RAT Lpar5 Lysophosphatidic acid receptor 5 1.917e-37 0.30
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 4.05e-37 0.31
VDAC2_HUMAN VDAC2 Voltage-dependent anion-selective channel protein 2 4.269e-37 0.29
ANT3_HUMAN SERPINC1 Antithrombin-III 2.43e-36 0.29
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 7.175e-35 0.38
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 2.647e-30 0.37
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 3.447e-29 0.32
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 5.575e-29 0.32
ADA33_HUMAN ADAM33 Disintegrin and metalloproteinase domain-containing protein 33 5.662e-29 0.30
KLK1_HUMAN KLK1 Kallikrein-1 1.154e-28 0.32
KLKB1_HUMAN KLKB1 Plasma kallikrein 1.915e-28 0.33
GPR88_HUMAN GPR88 Probable G-protein coupled receptor 88 2.061e-28 0.36
MMP8_RAT Mmp8 Neutrophil collagenase 2.333e-27 0.31
MMP9_RAT Mmp9 Matrix metalloproteinase-9 5.168e-27 0.31
ACACB_HUMAN ACACB Acetyl-CoA carboxylase 2 9.397e-25 0.33
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 7.193e-24 0.29
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 2.497e-23 0.30
PTN14_HUMAN PTPN14 Tyrosine-protein phosphatase non-receptor type 14 2.847e-23 0.29
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 9.303e-22 0.35
KCNQ4_HUMAN KCNQ4 Potassium voltage-gated channel subfamily KQT member 4 1.778e-21 0.34
SOAT1_CHLAE SOAT1 Sterol O-acyltransferase 1 1.854e-21 0.33
NORA_STAAU norA Quinolone resistance protein NorA 6.505e-21 0.31
TIMP3_RAT Timp3 Metalloproteinase inhibitor 3 1.207e-20 0.31
NEP_PIG MME Neprilysin 1.24e-20 0.31
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 2.81e-20 0.30
PSB10_HUMAN PSMB10 Proteasome subunit beta type-10 4.048e-20 0.31
MC3R_HUMAN MC3R Melanocortin receptor 3 5.136e-20 0.37
ITA4_HUMAN ITGA4 Integrin alpha-4 1.356e-19 0.37
CCKAR_MOUSE Cckar Cholecystokinin receptor type A 1.958e-19 0.32
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 7.06e-19 0.32
CASP8_HUMAN CASP8 Caspase-8 7.441e-19 0.34
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 1.172e-18 0.31
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.221e-18 0.36
PSA1_HUMAN PSMA1 Proteasome subunit alpha type-1 2.677e-18 0.31
PSA2_HUMAN PSMA2 Proteasome subunit alpha type-2 2.677e-18 0.31
PSA3_HUMAN PSMA3 Proteasome subunit alpha type-3 2.677e-18 0.31
PSA4_HUMAN PSMA4 Proteasome subunit alpha type-4 2.677e-18 0.31
PSA5_HUMAN PSMA5 Proteasome subunit alpha type-5 2.677e-18 0.31
PSA6_HUMAN PSMA6 Proteasome subunit alpha type-6 2.677e-18 0.31
PSA7_HUMAN PSMA7 Proteasome subunit alpha type-7 2.677e-18 0.31
PSB11_HUMAN PSMB11 Proteasome subunit beta type-11 2.677e-18 0.31
PSB3_HUMAN PSMB3 Proteasome subunit beta type-3 2.677e-18 0.31
PSB4_HUMAN PSMB4 Proteasome subunit beta type-4 2.677e-18 0.31
PSB6_HUMAN PSMB6 Proteasome subunit beta type-6 2.677e-18 0.31
PSB7_HUMAN PSMB7 Proteasome subunit beta type-7 2.677e-18 0.31
PSMA8_HUMAN PSMA8 Proteasome subunit alpha-type 8 2.677e-18 0.31
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 4.879e-18 0.29
CC14A_HUMAN CDC14A Dual specificity protein phosphatase CDC14A 4.879e-18 0.29
DUS10_HUMAN DUSP10 Dual specificity protein phosphatase 10 4.879e-18 0.29
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 1.098e-17 0.35
PTPRB_HUMAN PTPRB Receptor-type tyrosine-protein phosphatase beta 1.234e-17 0.32
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 1.341e-17 0.32
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 2.172e-17 0.33
BRPF1_HUMAN BRPF1 Peregrin 2.389e-17 0.37
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 4.743e-17 0.31
ITB1_HUMAN ITGB1 Integrin beta-1 1.11e-16 0.37
SOAT2_CHLAE SOAT2 Sterol O-acyltransferase 2 1.11e-16 0.33
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.11e-15 0.38
Q95PM0_TRYBR rhodesain Cysteine protease 1.998e-15 0.33
RENI_HUMAN REN Renin 1.998e-15 0.32
PEN2_HUMAN PSENEN Gamma-secretase subunit PEN-2 6.661e-15 0.41
CASP1_HUMAN CASP1 Caspase-1 7.883e-15 0.34
APH1A_HUMAN APH1A Gamma-secretase subunit APH-1A 1.221e-14 0.41
APH1B_HUMAN APH1B Gamma-secretase subunit APH-1B 1.221e-14 0.41
NICA_HUMAN NCSTN Nicastrin 1.221e-14 0.41
PSN2_HUMAN PSEN2 Presenilin-2 1.288e-14 0.41
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.577e-14 0.41
HNF4A_RAT Hnf4a Hepatocyte nuclear factor 4-alpha 1.754e-14 0.29
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 3.264e-14 0.31
PSN1_HUMAN PSEN1 Presenilin-1 4.508e-14 0.41
CASP7_HUMAN CASP7 Caspase-7 4.585e-14 0.34
UR2R_HUMAN UTS2R Urotensin-2 receptor 4.974e-14 0.35
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 6.95e-14 0.33
MC5R_HUMAN MC5R Melanocortin receptor 5 1.106e-13 0.37
CATK_HUMAN CTSK Cathepsin K 4.247e-13 0.32
DRD1_PIG DRD1 D(1A) dopamine receptor 4.492e-13 0.31
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 5.338e-13 0.28
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 5.338e-13 0.28
HRH2_CAVPO HRH2 Histamine H2 receptor 5.541e-13 0.33
DRD2_RAT Drd2 D(2) dopamine receptor 6.464e-13 0.38
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 1.103e-12 0.31
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 1.373e-12 0.37
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 3.076e-12 0.37
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 5.049e-12 0.31
SOAT1_HUMAN SOAT1 Sterol O-acyltransferase 1 5.183e-12 0.33
HRH2_HUMAN HRH2 Histamine H2 receptor 5.25e-12 0.33
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 5.319e-12 0.41
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 6.343e-12 0.30
HNF4A_HUMAN HNF4A Hepatocyte nuclear factor 4-alpha 8.9e-12 0.29
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.023e-11 0.33
EDNRA_RAT Ednra Endothelin-1 receptor 1.536e-11 0.33
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.749e-11 0.37
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 2.099e-11 0.31
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 2.793e-11 0.31
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 8.216e-11 0.30
TRY3_HUMAN PRSS3 Trypsin-3 9.695e-11 0.29
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 1.041e-10 0.31
CASP3_HUMAN CASP3 Caspase-3 2.065e-10 0.34
DRD4_HUMAN DRD4 D(4) dopamine receptor 2.147e-10 0.35
HRH1_CAVPO HRH1 Histamine H1 receptor 2.153e-10 0.33
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 3.674e-10 0.30
DRD3_HUMAN DRD3 D(3) dopamine receptor 3.905e-10 0.36
PTPRA_HUMAN PTPRA Receptor-type tyrosine-protein phosphatase alpha 5.587e-10 0.30
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 6.811e-10 0.31
UBCP1_HUMAN UBLCP1 Ubiquitin-like domain-containing CTD phosphatase 1 7.541e-10 0.29
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 7.811e-10 0.31
G3H407_CRIGR PROKR2 1.009e-09 0.35
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 1.057e-09 0.34
MMP1_HUMAN MMP1 Interstitial collagenase 1.62e-09 0.31
EDNRA_HUMAN EDNRA Endothelin-1 receptor 2.392e-09 0.35
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 2.944e-09 0.31
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 3.8e-09 0.33
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 4.15e-09 0.36
ILVB_YEAST ILV2 Acetolactate synthase catalytic subunit, mitochondrial 4.608e-09 0.28
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 6.293e-09 0.36
NEP_RABIT MME Neprilysin 6.68e-09 0.31
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 8.193e-09 0.31
G3I1B6_CRIGR 5-hydroxytryptamine receptor 8.252e-09 0.30
5HT1B_CRIGR HTR1B 5-hydroxytryptamine receptor 1B 1.043e-08 0.30
V2R_HUMAN AVPR2 Vasopressin V2 receptor 1.244e-08 0.33
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 1.309e-08 0.32
MC4R_RAT Mc4r Melanocortin receptor 4 1.335e-08 0.32
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 1.634e-08 0.28
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 1.7e-08 0.29
AMP1_PLAFQ M1 family aminopeptidase 2.398e-08 0.31
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 2.611e-08 0.33
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 3.038e-08 0.29
CATD_BOVIN CTSD Cathepsin D 3.125e-08 0.32
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 3.812e-08 0.37
EDNRB_HUMAN EDNRB Endothelin receptor type B 3.933e-08 0.35
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 4.105e-08 0.32
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 4.437e-08 0.30
RENI_RAT Ren1 Renin 4.482e-08 0.29
CATL1_HUMAN CTSL Cathepsin L1 6.494e-08 0.32
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 6.853e-08 0.33
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 7.724e-08 0.30
AMPN_HUMAN ANPEP Aminopeptidase N 8.228e-08 0.29
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 1.092e-07 0.30
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 1.41e-07 0.31
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 1.468e-07 0.30
NK1R_HUMAN TACR1 Substance-P receptor 1.553e-07 0.36
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 1.563e-07 0.29
PI2R_HUMAN PTGIR Prostacyclin receptor 1.683e-07 0.30
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 1.745e-07 0.29
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.848e-07 0.33
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 2.129e-07 0.29
MCLN3_HUMAN MCOLN3 Mucolipin-3 2.347e-07 0.31
PD1L1_HUMAN CD274 Programmed cell death 1 ligand 1 3.05e-07 0.28
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 3.544e-07 0.29
BRD1_HUMAN BRD1 Bromodomain-containing protein 1 4.058e-07 0.32
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 4.481e-07 0.29
CBPA1_HUMAN CPA1 Carboxypeptidase A1 4.755e-07 0.29
ECE1_RAT Ece1 Endothelin-converting enzyme 1 6.007e-07 0.29
BKRB1_HUMAN BDKRB1 B1 bradykinin receptor 6.422e-07 0.34
GLSK_HUMAN GLS Glutaminase kidney isoform, mitochondrial 7.427e-07 0.38
CBX7_HUMAN CBX7 Chromobox protein homolog 7 9.065e-07 0.31
ACHA_HUMAN CHRNA1 Acetylcholine receptor subunit alpha 9.253e-07 0.30
LKHA4_CAVPO LTA4H Leukotriene A-4 hydrolase 1.025e-06 0.32
CATB_BOVIN CTSB Cathepsin B 1.732e-06 0.30
CATD_HUMAN CTSD Cathepsin D 1.889e-06 0.34
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 2.017e-06 0.28
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 2.14e-06 0.34
PDS_SYNE7 pds 15-cis-phytoene desaturase 2.434e-06 0.28
PRIO_SHEEP PRNP Major prion protein 2.611e-06 0.29
RIR1_HHV11 RIR1 Ribonucleoside-diphosphate reductase large subunit 2.648e-06 0.29
PRIO_MESAU PRNP Major prion protein 2.849e-06 0.29
CML1_HUMAN CMKLR1 Chemokine-like receptor 1 3.138e-06 0.30
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 4.596e-06 0.29
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 4.683e-06 0.37
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 4.864e-06 0.33
EDNRB_RAT Ednrb Endothelin receptor type B 4.972e-06 0.29
Q8IL11_PLAF7 M17 leucyl aminopeptidase 6.036e-06 0.31
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 7.79e-06 0.32
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 8.517e-06 0.35
CATS_HUMAN CTSS Cathepsin S 9.665e-06 0.33

Bumetanide

S22A6_RAT Slc22a6 Solute carrier family 22 member 6 8.103e-33 1.00
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 6.003e-83 0.38
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 2.013e-61 0.32
FABH_STRP3 fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.039e-60 0.31
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 6.229e-57 0.38
FABH_STAAM fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.649e-46 0.29
CHMU_MYCTU Intracellular chorismate mutase 1.371e-45 0.36
SCMU_MYCTU Secreted chorismate mutase 9.991e-44 0.35
PA2A1_NAJMO Acidic phospholipase A2 CM-I 1.627e-37 0.30
FABH_HAEIN fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 3.56e-37 0.29
KAT1_HUMAN KYAT1 Kynurenine--oxoglutarate transaminase 1 1.377e-35 0.28
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 1.72e-34 0.31
GPAT1_MOUSE Gpam Glycerol-3-phosphate acyltransferase 1, mitochondrial 9.686e-32 0.34
PGES2_HUMAN PTGES2 Prostaglandin E synthase 2 2.932e-30 0.36
CRTM_STAAU crtM 4,4'-diapophytoene synthase 2.494e-27 0.33
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 2.643e-26 0.32
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 4.113e-26 0.31
CAH2_HUMAN CA2 Carbonic anhydrase 2 5.601e-26 0.37
AGTR1_PIG AGTR1 Type-1 angiotensin II receptor 1.541e-24 0.38
CAH4_BOVIN CA4 Carbonic anhydrase 4 2.342e-24 0.36
CEL_BOVIN CEL Bile salt-activated lipase 9.98e-22 0.33
CAH1_HUMAN CA1 Carbonic anhydrase 1 5.161e-20 0.37
NEUR3_HUMAN NEU3 Sialidase-3 5.708e-20 0.40
A85C_MYCTU fbpC Diacylglycerol acyltransferase/mycolyltransferase Ag85C 8.254e-20 0.31
PRTN3_HUMAN PRTN3 Myeloblastin 1.172e-19 0.31
CYNT_HELPY cynT Carbonic anhydrase 1.198e-19 0.34
S22A8_RAT Slc22a8 Solute carrier family 22 member 8 8.596e-19 0.30
KAT3_HUMAN KYAT3 Kynurenine--oxoglutarate transaminase 3 9.056e-18 0.28
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 1.11e-15 0.32
CAH9_HUMAN CA9 Carbonic anhydrase 9 5.995e-15 0.39
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 8.216e-15 0.41
CAH7_HUMAN CA7 Carbonic anhydrase 7 8.549e-15 0.37
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 9.992e-15 0.32
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.787e-14 0.37
CTRB_BOVIN Chymotrypsinogen B 8.893e-14 0.28
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 9.637e-14 0.33
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 9.781e-14 0.31
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 1.06e-13 0.39
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 1.131e-13 0.30
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 2.877e-13 0.37
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 7.303e-13 0.34
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.064e-12 0.39
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 1.327e-12 0.34
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.5e-12 0.32
EST1_RABIT Liver carboxylesterase 1 1.72e-12 0.30
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 2.732e-12 0.31
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 4.935e-12 0.32
CAH13_HUMAN CA13 Carbonic anhydrase 13 1.197e-11 0.37
O39930_9HEPC NS5b RNA-directed RNA polymerase 2.343e-11 0.32
MAP2_HUMAN METAP2 Methionine aminopeptidase 2 2.677e-11 0.33
STS_HUMAN STS Steryl-sulfatase 3.477e-11 0.32
FDFT_HUMAN FDFT1 Squalene synthase 4.086e-11 0.33
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 5.001e-11 0.35
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 6.523e-11 0.28
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 8.097e-11 0.33
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.374e-10 0.34
CAH14_HUMAN CA14 Carbonic anhydrase 14 2.48e-10 0.37
CAH2_BOVIN CA2 Carbonic anhydrase 2 2.567e-10 0.30
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 3.022e-10 0.30
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 4.37e-10 0.34
P2RX2_RAT P2rx2 P2X purinoceptor 2 4.517e-10 0.29
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 6.156e-10 0.31
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 9.181e-10 0.28
CAH6_HUMAN CA6 Carbonic anhydrase 6 9.424e-10 0.37
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 2.861e-09 0.33
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 2.975e-09 0.34
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 3.06e-09 0.28
CATG_HUMAN CTSG Cathepsin G 3.22e-09 0.32
Q9JN24_ECOLX def Peptide deformylase 3.261e-09 0.31
HRP1_PLAFA Histidine-rich protein PFHRP-II 3.8e-09 0.34
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 4.418e-09 0.32
NCEH1_HUMAN NCEH1 Neutral cholesterol ester hydrolase 1 8.97e-09 0.30
O77078_PLAFA fabH Beta-ketoacyl-acyl carrier protein synthase III 1.751e-08 0.28
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 2.926e-08 0.35
CAH3_HUMAN CA3 Carbonic anhydrase 3 3.264e-08 0.37
C0IX24_STYPI CA2 Carbonic anhydrase 3.841e-08 0.29
A5H660_SCHMA HDAC8 Histone deacetylase 8 4.199e-08 0.30
B2V8E3_SULSY Carbonate dehydratase 7.596e-08 0.29
B5SU02_STYPI CA Alpha carbonic anhydrase 7.596e-08 0.29
Q31FD6_HYDCU Carbonic anhydrase, alpha family 7.596e-08 0.29
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 9.002e-08 0.29
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 1.019e-07 0.30
CAH4_HUMAN CA4 Carbonic anhydrase 4 1.136e-07 0.37
PTN1_RAT Ptpn1 Tyrosine-protein phosphatase non-receptor type 1 1.149e-07 0.28
A6YCJ1_9METZ Astrosclerin-3 1.884e-07 0.29
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 2.107e-07 0.30
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 2.131e-07 0.32
RARB_HUMAN RARB Retinoic acid receptor beta 2.209e-07 0.32
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 2.659e-07 0.37
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 3.044e-07 0.32
FA10_HUMAN F10 Coagulation factor X 4.065e-07 0.38
MMP13_HUMAN MMP13 Collagenase 3 4.365e-07 0.36
Q56D28_CAVPO CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells 4.44e-07 0.30
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 5.06e-07 0.30
AGTRA_RAT Agtr1 Type-1A angiotensin II receptor 6.126e-07 0.29
EGLN2_HUMAN EGLN2 Egl nine homolog 2 7.764e-07 0.30
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 9.38e-07 0.31
GPR18_HUMAN GPR18 N-arachidonyl glycine receptor 1.819e-06 0.30
TLR8_HUMAN TLR8 Toll-like receptor 8 1.907e-06 0.30
EST2_HUMAN CES2 Cocaine esterase 2.345e-06 0.30
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 2.553e-06 0.32
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 2.779e-06 0.31
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 2.987e-06 0.30
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 3.038e-06 0.32
5NTD_RAT Nt5e 5'-nucleotidase 3.12e-06 0.29
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 3.477e-06 0.28
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 3.5e-06 0.30
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 3.606e-06 0.29
THB_HUMAN THRB Thyroid hormone receptor beta 4.101e-06 0.32
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 4.23e-06 0.30
Q6UCJ9_TOXGO ENR Enoyl-acyl carrier reductase 5.176e-06 0.36
AMP1_PLAFQ M1 family aminopeptidase 6.161e-06 0.31
THA_HUMAN THRA Thyroid hormone receptor alpha 6.449e-06 0.32
TLR7_HUMAN TLR7 Toll-like receptor 7 6.595e-06 0.30
FEN1_HUMAN FEN1 Flap endonuclease 1 6.991e-06 0.31

Terbinafine

ERG1_HUMAN SQLE Squalene monooxygenase 1.735e-32 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.01698 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.02618 1.00
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 0.1887 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.2941 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.7204 1.00
CRTN_STAAE crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 3.47e-102 0.61
CHS1_CANAX CHS1 Chitin synthase 1 2.756e-76 0.41
CRTN_STAA3 crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 1.472e-69 0.40
CRTN_STAAW crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 9.11e-58 0.40
CRTN_STAAM crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 5.499e-37 0.40
ANM1_RAT Prmt1 Protein arginine N-methyltransferase 1 1.599e-14 0.36
AMPN_MOUSE Anpep Aminopeptidase N 9.112e-11 0.29

Phenoxybenzamine

S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.414e-25 1.00
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 1.558e-20 1.00
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.785e-14 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.001278 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.3369 1.00
PDS_SYNE7 pds 15-cis-phytoene desaturase 1.067e-76 0.38
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 3.853e-51 0.38
EPOR_HUMAN EPOR Erythropoietin receptor 1.106e-39 0.34
G6PC_HUMAN G6PC Glucose-6-phosphatase 7.393e-29 0.33
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 2.436e-22 0.33
SCYD_MAGO7 SDH1 Scytalone dehydratase 3.331e-16 0.36
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 5.329e-15 0.29
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 2.165e-14 0.36
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.875e-14 0.36
CALM_BOVIN CALM Calmodulin 2.98e-13 0.36
FDFT_RAT Fdft1 Squalene synthase 3.65e-12 0.34
MMP12_MOUSE Mmp12 Macrophage metalloelastase 3.679e-12 0.28
GPR88_HUMAN GPR88 Probable G-protein coupled receptor 88 5.443e-11 0.35
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 1.077e-10 0.40
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 3.87e-10 0.40
CALM1_HUMAN CALM1 Calmodulin-1 4.88e-10 0.36
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 1.629e-09 0.29
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 3.692e-08 0.34
ERG2_YEAST ERG2 C-8 sterol isomerase 7.894e-08 0.30
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 6.603e-07 0.35
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.022e-06 0.30
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.711e-06 0.35
NORA_STAAU norA Quinolone resistance protein NorA 2.149e-06 0.32
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 2.644e-06 0.29
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 3.572e-06 0.29
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 8.627e-06 0.30

Azacitidine

DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 3.325e-25 1.00
AA1R_RAT Adora1 Adenosine receptor A1 1.17e-189 0.58
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 2.747e-167 0.49
ADOK_MYCTO adoK Adenosine kinase 2.406e-157 0.42
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 6.921e-151 0.39
ADK_TOXGO AK Adenosine kinase 7.526e-150 0.54
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 5.647e-137 0.40
OXGR1_RAT Oxgr1 2-oxoglutarate receptor 1 1.138e-136 0.36
CDD_MOUSE Cda Cytidine deaminase 1.792e-124 0.57
AA2AR_RAT Adora2a Adenosine receptor A2a 1.112e-122 0.57
AA1R_CHICK ADORA1 Adenosine receptor A1 4.953e-120 0.43
S28A2_HUMAN SLC28A2 Sodium/nucleoside cotransporter 2 5.702e-118 0.35
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 2.56e-113 0.41
DNPH1_HUMAN DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 3.206e-106 0.34
AA1R_RABIT ADORA1 Adenosine receptor A1 1.43e-105 0.33
DNPH1_RAT Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 4.422e-104 0.34
DCAM_HUMAN AMD1 S-adenosylmethionine decarboxylase proenzyme 5.526e-104 0.39
AA3R_RABIT ADORA3 Adenosine receptor A3 1.103e-103 0.33
C3SIU2_ECOLX metJ Met repressor 2.685e-103 0.35
MBTA_MYCTU mbtA Salicyl-AMP ligase / salicyl-S-ArCP synthetase 7.805e-103 0.34
CDD_HUMAN CDA Cytidine deaminase 2.143e-101 0.57
IF4E_MOUSE Eif4e Eukaryotic translation initiation factor 4E 2.019e-99 0.38
IF4E_RABIT EIF4E Eukaryotic translation initiation factor 4E 7.942e-99 0.38
AA1R_CAVPO ADORA1 Adenosine receptor A1 8.679e-92 0.58
AA3R_HUMAN ADORA3 Adenosine receptor A3 1.574e-86 0.55
MTAP_MOUSE Mtap S-methyl-5'-thioadenosine phosphorylase 2.519e-86 0.38
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 3.465e-86 0.37
P2RY1_RAT P2ry1 P2Y purinoceptor 1 5.746e-83 0.40
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 3.896e-80 0.46
ADK_HUMAN ADK Adenosine kinase 2.254e-79 0.54
SAHH_HUMAN AHCY Adenosylhomocysteinase 1.363e-78 0.53
PUR6_CHICK AIRC Multifunctional protein ADE2 8.877e-75 0.42
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 4.273e-74 0.38
AA1R_HUMAN ADORA1 Adenosine receptor A1 4.558e-71 0.55
ADA_MOUSE Ada Adenosine deaminase 2.056e-68 0.57
DOT1L_HUMAN DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 3.819e-68 0.36
RASK_HUMAN KRAS GTPase KRas 4.528e-67 0.36
BIP_HUMAN HSPA5 Endoplasmic reticulum chaperone BiP 1.058e-66 0.46
P2RY4_RAT P2ry4 P2Y purinoceptor 4 1.063e-65 0.40
KITH_VZVD TK Thymidine kinase 6.479e-65 0.40
SPEE_HUMAN SRM Spermidine synthase 8.218e-64 0.32
KAD2_RAT Ak2 Adenylate kinase 2, mitochondrial 1.142e-62 0.40
AA3R_RAT Adora3 Adenosine receptor A3 5.017e-62 0.54
HSP7C_HUMAN HSPA8 Heat shock cognate 71 kDa protein 1.627e-60 0.46
IMDH2_MOUSE Impdh2 Inosine-5'-monophosphate dehydrogenase 2 4.162e-60 0.35
ASNS_HUMAN ASNS Asparagine synthetase [glutamine-hydrolyzing] 2.06e-59 0.33
KAD3_RAT Ak3 GTP:AMP phosphotransferase AK3, mitochondrial 2.229e-58 0.40
SYQ_HUMAN QARS1 Glutamine--tRNA ligase 2.56e-58 0.34
PYRF_YEAST URA3 Orotidine 5'-phosphate decarboxylase 1.14e-57 0.44
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 1.656e-57 0.36
Q99MI5_RAT LOC100912604 Spermidine synthase 2.186e-57 0.32
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 1.963e-55 0.39
NADK_HUMAN NADK NAD kinase 3.422e-55 0.36
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 2.166e-54 0.54
KTHY_HUMAN DTYMK Thymidylate kinase 1.783e-53 0.31
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 2.101e-51 0.38
P2Y11_HUMAN P2RY11 P2Y purinoceptor 11 3.559e-51 0.39
DHE3_BOVIN GLUD1 Glutamate dehydrogenase 1, mitochondrial 3.87e-51 0.33
PQSA_PSEAE pqsA Anthranilate--CoA ligase 5.567e-51 0.32
RN5A_MOUSE Rnasel 2-5A-dependent ribonuclease 8.407e-51 0.34
KITH_VZVO TK Thymidine kinase 3.093e-50 0.35
MACD1_HUMAN MACROD1 ADP-ribose glycohydrolase MACROD1 7.582e-50 0.40
MACD2_HUMAN MACROD2 ADP-ribose glycohydrolase MACROD2 7.582e-50 0.40
SPSY_HUMAN SMS Spermine synthase 1.486e-49 0.32
ENPP1_RAT Enpp1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 2.201e-49 0.41
ENTE_ECOLI entE Enterobactin synthase component E 2.72e-49 0.31
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 3.366e-49 0.40
NADK1_LISMF nadK1 NAD kinase 1 3.639e-49 0.39
NADK_STAAC nadK NAD kinase 3.639e-49 0.39
HSP7C_BOVIN HSPA8 Heat shock cognate 71 kDa protein 1.202e-48 0.39
WALK_STAAU walK Sensor protein kinase WalK 1.202e-48 0.39
SYRC_HUMAN RARS1 Arginine--tRNA ligase, cytoplasmic 1.953e-48 0.31
PYRF_METTH pyrF Orotidine 5'-phosphate decarboxylase 2.879e-48 0.33
PARG_BOVIN PARG Poly(ADP-ribose) glycohydrolase 3.108e-48 0.34
ADA_BOVIN ADA Adenosine deaminase 3.695e-48 0.63
IMDH1_HUMAN IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 6.824e-48 0.35
P2RX5_RAT P2rx5 P2X purinoceptor 5 6.859e-46 0.38
P2RX6_RAT P2rx6 P2X purinoceptor 6 6.859e-46 0.38
POLG_POL1M Genome polyprotein 9.43e-46 0.36
KMT5C_HUMAN KMT5C Histone-lysine N-methyltransferase KMT5C 3.164e-45 0.36
SETB1_HUMAN SETDB1 Histone-lysine N-methyltransferase SETDB1 3.164e-45 0.36
METK2_RAT Mat2a S-adenosylmethionine synthase isoform type-2 4.407e-45 0.36
G3P_HUMAN GAPDH Glyceraldehyde-3-phosphate dehydrogenase 8.361e-44 0.57
SYS_ECOLI serS Serine--tRNA ligase 8.416e-44 0.35
ISPE_ECOLI ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 3.453e-43 0.34
ENPL_PIG HSP90B1 Endoplasmin 1.122e-42 0.34
RN5A_HUMAN RNASEL 2-5A-dependent ribonuclease 1.361e-42 0.34
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 3.163e-42 0.62
MSHC_MYCTU mshC L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 5.166e-42 0.33
SETD2_HUMAN SETD2 Histone-lysine N-methyltransferase SETD2 7.441e-41 0.32
SAHH_PLAF7 Adenosylhomocysteinase 9.648e-41 0.33
SYD_ECOLI aspS Aspartate--tRNA ligase 2.671e-40 0.32
Q8T6J6_PLAFA ompdc Orotidine 5'-monophosphate decarboxylase 5.881e-40 0.32
Q9HWG3_PSEAE pchD Pyochelin biosynthesis protein PchD 9.26e-40 0.32
KITH_RAT Tk1 Thymidine kinase, cytosolic 3.171e-38 0.33
BIRA_ECOLI birA Bifunctional ligase/repressor BirA 4.754e-38 0.30
SYY_ECOLI tyrS Tyrosine--tRNA ligase 9.681e-38 0.30
P2RY2_RAT P2ry2 P2Y purinoceptor 2 1.627e-37 0.30
HARS1_HUMAN HARS1 Histidine--tRNA ligase, cytoplasmic 8.297e-37 0.29
S28A2_RAT Slc28a2 Sodium/nucleoside cotransporter 2 1.332e-36 0.29
GGTA1_BOVIN GGTA1 N-acetyllactosaminide alpha-1,3-galactosyltransferase 2.333e-36 0.29
Q8KHJ3_NEIME lgtC Alpha 1,4 galactosyltransferase 2.333e-36 0.29
UBA7_HUMAN UBA7 Ubiquitin-like modifier-activating enzyme 7 3.875e-36 0.29
ENTP1_BOVIN ENTPD1 Ectonucleoside triphosphate diphosphohydrolase 1 1.097e-35 0.28
ADA_HUMAN ADA Adenosine deaminase 3.052e-35 0.53
S29A1_RAT Slc29a1 Equilibrative nucleoside transporter 1 3.098e-32 0.40
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 1.644e-31 0.35
B4EH87_BURCJ Lectin 3.983e-31 0.33
AMPD1_RABIT AMPD1 AMP deaminase 1 4.15e-30 0.37
GPR17_HUMAN GPR17 Uracil nucleotide/cysteinyl leukotriene receptor 1.111e-29 0.36
CDK12_HUMAN CDK12 Cyclin-dependent kinase 12 2.203e-29 0.36
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 9.289e-28 0.32
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 3.057e-27 0.31
ANM7_HUMAN PRMT7 Protein arginine N-methyltransferase 7 5.245e-27 0.33
P2RY6_RAT P2ry6 P2Y purinoceptor 6 8.081e-27 0.31
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 4.4e-26 0.38
SYL_ECOLI leuS Leucine--tRNA ligase 1.42e-25 0.32
RNAS1_HUMAN RNASE1 Ribonuclease pancreatic 3.865e-25 0.31
RNAS2_HUMAN RNASE2 Non-secretory ribonuclease 3.865e-25 0.31
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 1.611e-24 0.38
MGMT_HUMAN MGMT Methylated-DNA--protein-cysteine methyltransferase 4.048e-24 0.32
G3PC_LEIME GAPC Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 4.652e-24 0.30
HEXB_HUMAN HEXB Beta-hexosaminidase subunit beta 6.243e-24 0.29
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 9.723e-24 0.44
UBA6_HUMAN UBA6 Ubiquitin-like modifier-activating enzyme 6 2.847e-23 0.29
SAHH_MOUSE Ahcy Adenosylhomocysteinase 1.819e-22 0.33
Q4VQ11_PIG Adenosine receptor A1 1.933e-22 0.44
BPL1_HUMAN HLCS Biotin--protein ligase 1.64e-21 0.30
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 1.71e-21 0.41
P2RX4_RAT P2rx4 P2X purinoceptor 4 2.764e-21 0.38
SAHH_RAT Ahcy Adenosylhomocysteinase 2.814e-21 0.36
PARG_HUMAN PARG Poly(ADP-ribose) glycohydrolase 3.472e-21 0.34
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 3.533e-21 0.37
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 5.346e-21 0.54
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 6.907e-21 0.40
A3RLP8_CHV1 UL23 Thymidine kinase 1.202e-20 0.29
KITH_HUMAN TK1 Thymidine kinase, cytosolic 4.068e-20 0.38
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 5.798e-20 0.37
SYI_ECOLI ileS Isoleucine--tRNA ligase 8.357e-20 0.32
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 9.13e-20 0.41
P2RX1_RAT P2rx1 P2X purinoceptor 1 4.253e-19 0.39
GLCM_BOVIN GBA Lysosomal acid glucosylceramidase 1.126e-18 0.30
HEXA_HUMAN HEXA Beta-hexosaminidase subunit alpha 1.523e-18 0.29
MRAY_ECOLI mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase 1.523e-18 0.29
Q8TA74_HEMPU Ryanodine receptor 1.523e-18 0.29
METK1_RAT Mat1a S-adenosylmethionine synthase isoform type-1 4.879e-18 0.29
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 6.168e-18 0.30
IF4E_HUMAN EIF4E Eukaryotic translation initiation factor 4E 2.045e-17 0.35
PANC_MYCTU panC Pantothenate synthetase 3.625e-17 0.36
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 1.11e-16 0.50
DCAM_RAT Amd1 S-adenosylmethionine decarboxylase proenzyme 2.22e-16 0.39
Q9HX69_PSEAE rocR RocR 3.331e-16 0.31
UMPS_HUMAN UMPS Uridine 5'-monophosphate synthase 5.551e-16 0.30
IUNH_CRIFA IUNH Inosine-uridine preferring nucleoside hydrolase 1.554e-15 0.30
O15727_TRYBB Inosine-adenosine-guanosine-nucleoside hydrolase 1.554e-15 0.30
SAHH2_HUMAN AHCYL1 S-adenosylhomocysteine hydrolase-like protein 1 3.331e-15 0.29
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 3.664e-15 0.29
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 3.775e-15 0.34
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 5.329e-15 0.37
P96884_MYCTO birA BirA bifunctional protein 6.55e-15 0.28
DPOLB_HUMAN POLB DNA polymerase beta 2.32e-14 0.31
SYMC_HUMAN MARS1 Methionine--tRNA ligase, cytoplasmic 2.509e-14 0.34
CD69_HUMAN CD69 Early activation antigen CD69 3.12e-14 0.35
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 3.12e-14 0.35
5NTD_HUMAN NT5E 5'-nucleotidase 5.629e-14 0.41
A0A0E7NXW5_STAAU birA Bifunctional ligase/repressor BirA 8.438e-14 0.30
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 1.14e-13 0.47
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 1.141e-13 0.41
ADCY5_RAT Adcy5 Adenylate cyclase type 5 2.142e-13 0.36
CCNK_HUMAN CCNK Cyclin-K 2.23e-13 0.36
SUV91_HUMAN SUV39H1 Histone-lysine N-methyltransferase SUV39H1 3.132e-13 0.36
RAB7A_HUMAN RAB7A Ras-related protein Rab-7a 7.717e-13 0.41
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 1.044e-12 0.41
AA1R_BOVIN ADORA1 Adenosine receptor A1 1.505e-12 0.54
NNMT_HUMAN NNMT Nicotinamide N-methyltransferase 1.88e-12 0.30
ADK_RAT Adk Adenosine kinase 1.883e-12 0.42
SYTC_HUMAN TARS1 Threonine--tRNA ligase 1, cytoplasmic 2.14e-12 0.32
TYPH_HUMAN TYMP Thymidine phosphorylase 3.15e-12 0.36
P2RY2_MOUSE P2ry2 P2Y purinoceptor 2 3.63e-12 0.30
ADCY2_RAT Adcy2 Adenylate cyclase type 2 3.938e-12 0.33
ADH1A_HUMAN ADH1A Alcohol dehydrogenase 1A 1.93e-11 0.31
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 4.705e-11 0.41
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 4.959e-11 0.30
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 6.069e-11 0.41
KMT2A_HUMAN KMT2A Histone-lysine N-methyltransferase 2A 5.064e-10 0.36
DCPS_HUMAN DCPS m7GpppX diphosphatase 8.157e-10 0.38
P2RX2_RAT P2rx2 P2X purinoceptor 2 1.588e-09 0.38
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 1.754e-09 0.37
E1BN64_BOVIN PDE3B Phosphodiesterase 3.077e-09 0.31
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 9.592e-09 0.46
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 1.258e-08 0.43
FGF1_HUMAN FGF1 Fibroblast growth factor 1 1.512e-08 0.28
CAH14_HUMAN CA14 Carbonic anhydrase 14 2.09e-08 0.37
5NTD_RAT Nt5e 5'-nucleotidase 2.329e-08 0.41
EZH1_HUMAN EZH1 Histone-lysine N-methyltransferase EZH1 2.661e-08 0.36
INMT_HUMAN INMT Indolethylamine N-methyltransferase 2.661e-08 0.36
HPRT_HUMAN HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 3.813e-08 0.43
KITM_HUMAN TK2 Thymidine kinase 2, mitochondrial 4.179e-08 0.28
CAH9_HUMAN CA9 Carbonic anhydrase 9 1.324e-07 0.40
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 1.371e-07 0.38
P2Y12_RAT P2ry12 P2Y purinoceptor 12 1.539e-07 0.39
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 1.617e-07 0.36
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 1.714e-07 0.46
PNPH_HUMAN PNP Purine nucleoside phosphorylase 1.787e-07 0.48
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 2.525e-07 0.29
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 3.521e-07 0.36
TOP1_HUMAN TOP1 DNA topoisomerase 1 4.637e-07 0.33
FGF2_HUMAN FGF2 Fibroblast growth factor 2 5.464e-07 0.28
ENPL_CANLF HSP90B1 Endoplasmin 5.981e-07 0.38
Q9Y0I0_9TRYP AT1 Adenosine transporter 1 7.679e-07 0.30
LEG9_HUMAN LGALS9 Galectin-9 9.412e-07 0.30
SYT_YERPE thrS Threonine--tRNA ligase 1.458e-06 0.32
OGT1_HUMAN OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 1.886e-06 0.31
CAH1_HUMAN CA1 Carbonic anhydrase 1 2.323e-06 0.40
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.361e-06 0.37
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.631e-06 0.29
AA1R_MOUSE Adora1 Adenosine receptor A1 5.72e-06 0.44

Dorzolamide

MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 6.44e-24 1.00
Q5TU56_ANOGA 1272966 Carbonic anhydrase 2.999e-22 1.00
CAN_YEAST NCE103 Carbonic anhydrase 2.718e-21 1.00
C0IX24_STYPI CA2 Carbonic anhydrase 1.959e-20 1.00
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 1.959e-20 1.00
B2V8E3_SULSY Carbonate dehydratase 1.163e-19 1.00
B5SU02_STYPI CA Alpha carbonic anhydrase 1.163e-19 1.00
Q31FD6_HYDCU Carbonic anhydrase, alpha family 1.163e-19 1.00
CAH_METTE Carbonic anhydrase 9.774e-19 1.00
A6YCJ1_9METZ Astrosclerin-3 1.246e-18 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 3.737e-17 1.00
CYNT_HELPY cynT Carbonic anhydrase 1.11e-16 1.00
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 4.984e-13 1.00
CAH13_MOUSE Ca13 Carbonic anhydrase 13 4.181e-12 1.00
CAH15_MOUSE Ca15 Carbonic anhydrase 15 6.71e-12 1.00
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 2.471e-11 1.00
Q6FTL6_CANGA NCE103 Carbonic anhydrase 2.471e-11 1.00
CAH4_HUMAN CA4 Carbonic anhydrase 4 3.53e-11 1.00
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 4.128e-10 1.00
CAH3_HUMAN CA3 Carbonic anhydrase 3 1.172e-08 1.00
CAN_CANAL NCE103 Carbonic anhydrase 3.372e-08 1.00
CAH4_BOVIN CA4 Carbonic anhydrase 4 4.186e-08 1.00
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.579e-06 1.00
CAH13_HUMAN CA13 Carbonic anhydrase 13 1.743e-06 1.00
CAH6_HUMAN CA6 Carbonic anhydrase 6 2.548e-06 1.00
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.483e-05 1.00
CAH14_HUMAN CA14 Carbonic anhydrase 14 0.002049 1.00
CAH7_HUMAN CA7 Carbonic anhydrase 7 0.006951 1.00
CAH12_HUMAN CA12 Carbonic anhydrase 12 0.5726 1.00
CAH9_HUMAN CA9 Carbonic anhydrase 9 0.6166 1.00

Zonisamide

CAH3_BOVIN CA3 Carbonic anhydrase 3 9.163e-22 1.00
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 4.694e-20 1.00
Q5TU56_ANOGA 1272966 Carbonic anhydrase 1.159e-18 1.00
CAN_YEAST NCE103 Carbonic anhydrase 7.296e-18 1.00
C0IX24_STYPI CA2 Carbonic anhydrase 3.794e-17 1.00
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 3.794e-17 1.00
B2V8E3_SULSY Carbonate dehydratase 2.22e-16 1.00
B5SU02_STYPI CA Alpha carbonic anhydrase 2.22e-16 1.00
Q31FD6_HYDCU Carbonic anhydrase, alpha family 2.22e-16 1.00
A6YCJ1_9METZ Astrosclerin-3 1.221e-15 1.00
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 2.487e-13 1.00
CYNT_HELPY cynT Carbonic anhydrase 3.307e-11 1.00
CAH15_MOUSE Ca15 Carbonic anhydrase 15 5.135e-10 1.00
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 1.529e-09 1.00
Q6FTL6_CANGA NCE103 Carbonic anhydrase 1.529e-09 1.00
CAN_CANAL NCE103 Carbonic anhydrase 2.191e-08 1.00
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 3.264e-08 1.00
CAH6_HUMAN CA6 Carbonic anhydrase 6 1.239e-07 1.00
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.022e-06 1.00
CAH13_HUMAN CA13 Carbonic anhydrase 13 1.242e-06 1.00
CAH9_HUMAN CA9 Carbonic anhydrase 9 5.739e-05 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 0.0001058 1.00
CAH4_HUMAN CA4 Carbonic anhydrase 4 0.0002175 1.00
CAH7_HUMAN CA7 Carbonic anhydrase 7 0.000539 1.00
CAH1_HUMAN CA1 Carbonic anhydrase 1 0.001106 1.00
CAH14_HUMAN CA14 Carbonic anhydrase 14 0.001814 1.00
AOFB_RAT Maob Amine oxidase [flavin-containing] B 0.05217 1.00
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 0.7342 1.00
CEL2A_RAT Cela2a Chymotrypsin-like elastase family member 2A 8.104e-18 0.28
COX2_HUMAN MT-CO2 Cytochrome c oxidase subunit 2 4.441e-15 0.29
O77078_PLAFA fabH Beta-ketoacyl-acyl carrier protein synthase III 1.322e-08 0.29
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.646e-06 0.32
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.849e-06 0.29
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 4.121e-06 0.38
CAH_METTE Carbonic anhydrase 7.112e-06 0.29

Diflunisal

S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 5.486e-20 1.00
TTHY_HUMAN TTR Transthyretin 2.851e-07 1.00
CAH1_HUMAN CA1 Carbonic anhydrase 1 0.01825 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 0.03832 1.00
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 5.556e-82 0.45
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 3.402e-59 0.48
MGRA_STAAU mgrA HTH-type transcriptional regulator MgrA 7.775e-53 0.42
IF4E_HUMAN EIF4E Eukaryotic translation initiation factor 4E 2.659e-42 0.45
3BHS2_HUMAN HSD3B2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 1.921e-39 0.31
TNF11_MOUSE Tnfsf11 Tumor necrosis factor ligand superfamily member 11 3.128e-37 0.39
HAOX2_HUMAN HAO2 Hydroxyacid oxidase 2 8.333e-36 0.28
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 5.039e-33 0.41
DHB14_HUMAN HSD17B14 17-beta-hydroxysteroid dehydrogenase 14 5.359e-29 0.35
PTN9_HUMAN PTPN9 Tyrosine-protein phosphatase non-receptor type 9 8.123e-29 0.39
TMPS4_HUMAN TMPRSS4 Transmembrane protease serine 4 1.535e-24 0.30
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 4.293e-24 0.33
Q2PCB5_DICLA ca Carbonic anhydrase 5.267e-22 0.32
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 5.743e-22 0.36
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 9.638e-21 0.41
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 1.576e-20 0.40
PTN22_HUMAN PTPN22 Tyrosine-protein phosphatase non-receptor type 22 2.114e-20 0.39
CO9_HUMAN C9 Complement component C9 4.22e-20 0.32
POLI_HUMAN POLI DNA polymerase iota 4.22e-20 0.32
POL_RSVP gag-pol Gag-Pol polyprotein 2.322e-19 0.31
AAKB2_HUMAN PRKAB2 5'-AMP-activated protein kinase subunit beta-2 6.741e-19 0.30
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 9.295e-19 0.38
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 3.789e-18 0.39
KMO_HUMAN KMO Kynurenine 3-monooxygenase 8.118e-18 0.45
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 2.19e-17 0.40
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 1.11e-16 0.32
POLH_HUMAN POLH DNA polymerase eta 1.11e-16 0.32
AL5AP_HUMAN ALOX5AP Arachidonate 5-lipoxygenase-activating protein 4.441e-16 0.36
NR0B2_HUMAN NR0B2 Nuclear receptor subfamily 0 group B member 2 1.887e-15 0.29
EST2_HUMAN CES2 Cocaine esterase 2.554e-15 0.42
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 3.997e-15 0.43
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 2.32e-14 0.39
O49150_SOLTU Lipoxygenase 2.542e-14 0.43
FUT7_HUMAN FUT7 Alpha-(1,3)-fucosyltransferase 7 1.242e-13 0.30
SC6A5_RAT Slc6a5 Sodium- and chloride-dependent glycine transporter 2 2.959e-12 0.32
KMO_MOUSE Kmo Kynurenine 3-monooxygenase 5.743e-12 0.29
Q9AQH7_STAAU dnaC Replicative DNA helicase 1.275e-11 0.28
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 5.412e-11 0.35
NOTUM_MOUSE Notum Palmitoleoyl-protein carboxylesterase NOTUM 6.708e-11 0.31
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 2.962e-10 0.39
SYPC_CANAX PRS Proline--tRNA ligase, cytoplasmic 5.251e-10 0.30
NOTUM_HUMAN NOTUM Palmitoleoyl-protein carboxylesterase NOTUM 8.645e-10 0.31
POLG_DEN2P Genome polyprotein 1.345e-09 0.42
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 3.009e-09 0.35
EST1_HUMAN CES1 Liver carboxylesterase 1 6.578e-09 0.42
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 1.082e-08 0.29
TPOR_HUMAN MPL Thrombopoietin receptor 1.732e-08 0.32
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 2.114e-08 0.35
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 4.168e-08 0.30
SCYD_MAGO7 SDH1 Scytalone dehydratase 4.169e-08 0.40
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 4.403e-08 0.33
HSP82_YEAST HSP82 ATP-dependent molecular chaperone HSP82 6.44e-08 0.29
INSR_MOUSE Insr Insulin receptor 7.707e-08 0.29
ESR2_HUMAN ESR2 Estrogen receptor beta 7.9e-08 0.40
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 8.043e-08 0.32
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 9.311e-08 0.35
ESR1_HUMAN ESR1 Estrogen receptor 9.541e-08 0.40
RARB_HUMAN RARB Retinoic acid receptor beta 1.784e-07 0.35
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.575e-07 0.34
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 2.596e-07 0.32
AVR2B_HUMAN ACVR2B Activin receptor type-2B 2.614e-07 0.34
OXDA_RAT Dao D-amino-acid oxidase 2.82e-07 0.29
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 3.409e-07 0.33
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 3.914e-07 0.39
HAOX2_RAT Hao2 Hydroxyacid oxidase 2 5.928e-07 0.29
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 7.888e-07 0.37
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 8.15e-07 0.40
AAKG1_HUMAN PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 9.442e-07 0.32
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 9.501e-07 0.31
PTPRG_HUMAN PTPRG Receptor-type tyrosine-protein phosphatase gamma 9.501e-07 0.31
DUS22_HUMAN DUSP22 Dual specificity protein phosphatase 22 1.595e-06 0.31
PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 2.042e-06 0.39
KKCC2_HUMAN CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 2.823e-06 0.33
MK14_MOUSE Mapk14 Mitogen-activated protein kinase 14 3.689e-06 0.29

Acetylsalicylic_acid

PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 1.77e-18 1.00
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.514e-08 1.00
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 0.0004267 1.00
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 0.1455 1.00
ITB3_HUMAN ITGB3 Integrin beta-3 0.4299 1.00
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 2.213e-86 0.47
CFAD_RAT Cfd Complement factor D 7.817e-70 0.56
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 1.255e-67 0.42
FABP7_HUMAN FABP7 Fatty acid-binding protein, brain 5.257e-57 0.31
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 3.773e-54 0.31
PHHY_PSEFL pobA p-hydroxybenzoate hydroxylase 2.433e-48 0.38
ILVB_ARATH ALS Acetolactate synthase, chloroplastic 9.262e-48 0.35
RAGE_RAT Ager Advanced glycosylation end product-specific receptor 1.968e-44 0.35
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 3.054e-41 0.47
COX1_SHEEP MT-CO1 Cytochrome c oxidase subunit 1 7.528e-39 0.31
ERF3_YEAST SUP35 Eukaryotic peptide chain release factor GTP-binding subunit 1.572e-36 0.29
Q8S3J0_BROTE ALS Acetolactate synthase 3.875e-36 0.29
3HAO_HUMAN HAAO 3-hydroxyanthranilate 3,4-dioxygenase 1.097e-35 0.28
3HAO_RAT Haao 3-hydroxyanthranilate 3,4-dioxygenase 1.097e-35 0.28
K4JQ36_LAOST ace2 Carboxylic ester hydrolase 4.527e-34 0.33
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 1.681e-32 0.36
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 2.107e-31 0.31
FABH_STRP3 fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 4.33e-30 0.31
EST1_RABIT Liver carboxylesterase 1 7.652e-30 0.35
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 7.898e-29 0.30
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 5.726e-28 0.35
HMGB1_HUMAN HMGB1 High mobility group protein B1 5.379e-25 0.31
FABH_STAAM fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 7.143e-25 0.31
PA2A1_ECHCA Acidic phospholipase A2 EC-I 3.169e-24 0.30
PA2B1_NAJME Basic phospholipase A2 1 3.169e-24 0.30
PA2BA_PROFL Basic phospholipase A2 PLA-A 3.169e-24 0.30
STXA_SHIDY stxA Shiga toxin subunit A 4.713e-24 0.31
Q44079_AERHY cphA2 Beta-lactamase 6.243e-24 0.29
Q7YWJ9_MUSDO Ache Carboxylic ester hydrolase 7.388e-24 0.33
Q9NJH6_NEPCI AO-AChE Ace-orthologous acetylcholinesterase 7.388e-24 0.33
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 9.145e-24 0.47
FABPL_HUMAN FABP1 Fatty acid-binding protein, liver 1.605e-23 0.29
BLAB_SERMA Metallo-beta-lactamase type 2 6.377e-23 0.28
CCR2_MOUSE Ccr2 C-C chemokine receptor type 2 4.671e-22 0.37
TLR1_MOUSE Tlr1 Toll-like receptor 1 3.219e-20 0.39
TLR2_MOUSE Tlr2 Toll-like receptor 2 3.219e-20 0.39
EST2_HUMAN CES2 Cocaine esterase 2.192e-19 0.35
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.336e-18 0.32
AOX_TRYBB AOX Alternative oxidase, mitochondrial 4.358e-18 0.30
MOT4_HUMAN SLC16A3 Monocarboxylate transporter 4 7.689e-18 0.30
MCR_RAT Nr3c2 Mineralocorticoid receptor 8.153e-18 0.29
EPHB_MYCTO Epoxide hydrolase B 9.056e-18 0.28
FABPI_HUMAN FABP2 Fatty acid-binding protein, intestinal 1.11e-16 0.32
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 3.553e-15 0.35
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 7.55e-14 0.30
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 8.082e-14 0.38
EST1_HUMAN CES1 Liver carboxylesterase 1 2.067e-13 0.35
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 3.211e-13 0.37
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 3.514e-13 0.28
TTHY_HUMAN TTR Transthyretin 5.752e-13 0.34
DNLI1_HUMAN LIG1 DNA ligase 1 1.4e-12 0.31
CAH15_MOUSE Ca15 Carbonic anhydrase 15 2.071e-12 0.38
BXE_CLOBO botE Botulinum neurotoxin type E 4.114e-12 0.30
Q9NBA7_PLAFA Cysteine protease falcipain-3 4.838e-12 0.33
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 9.7e-12 0.29
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 1.717e-11 0.31
ACRO_HUMAN ACR Acrosin 4.524e-11 0.39
ITF2_HUMAN TCF4 Transcription factor 4 5.659e-11 0.29
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 6.407e-11 0.32
T1QYY3_9HIV1 int Integrase 6.878e-11 0.29
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 1.029e-10 0.29
NR4A1_HUMAN NR4A1 Nuclear receptor subfamily 4 group A member 1 1.059e-10 0.40
J7HAW4_RAPRA Acetolactate synthase 1.105e-10 0.29
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 1.105e-10 0.29
HCN1_HUMAN HCN1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 1.532e-10 0.28
FABP5_HUMAN FABP5 Fatty acid-binding protein 5 3.919e-10 0.31
CAH13_MOUSE Ca13 Carbonic anhydrase 13 4.544e-10 0.38
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 6.413e-10 0.42
PYGL_RAT Pygl Glycogen phosphorylase, liver form 7.541e-10 0.29
BLA1_STEMA Metallo-beta-lactamase L1 type 3 1.337e-09 0.31
MAP1_ECOLI map Methionine aminopeptidase 1.557e-09 0.39
IL8_HUMAN CXCL8 Interleukin-8 2.705e-09 0.31
AGTR1_CAVPO AGTR1 Type-1 angiotensin II receptor 4.904e-09 0.30
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 6.362e-09 0.38
Q9BEG3_BOVIN 5-lipoxygenase 1.419e-08 0.43
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 2.684e-08 0.40
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 3.386e-08 0.29
1433G_HUMAN YWHAG 14-3-3 protein gamma 3.985e-08 0.29
CAH3_HUMAN CA3 Carbonic anhydrase 3 4.467e-08 0.34
UCHL1_HUMAN UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1 8.323e-08 0.32
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.498e-07 0.42
CAH3_BOVIN CA3 Carbonic anhydrase 3 1.669e-07 0.32
APEX1_HUMAN APEX1 DNA-(apurinic or apyrimidinic site) lyase 1.693e-07 0.43
O40947_HHV8 ORF 73 2.137e-07 0.29
CYSP_PLAFA Trophozoite cysteine proteinase 2.239e-07 0.31
REV_HV1H2 rev Protein Rev 2.786e-07 0.28
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 4.171e-07 0.32
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 5.365e-07 0.30
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 7.668e-07 0.35
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 9.167e-07 0.38
TLR4_MOUSE Tlr4 Toll-like receptor 4 9.28e-07 0.31
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 9.452e-07 0.30
O77240_CHOFU EcR Ecdysone receptor isoform A 1.683e-06 0.29
FACE2_HUMAN RCE1 CAAX prenyl protease 2 1.735e-06 0.35
TERT_HUMAN TERT Telomerase reverse transcriptase 1.759e-06 0.35
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 2.292e-06 0.38
PTPRG_HUMAN PTPRG Receptor-type tyrosine-protein phosphatase gamma 2.473e-06 0.29
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 2.996e-06 0.38
USP_DROME usp Protein ultraspiracle 3.596e-06 0.33
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 4.056e-06 0.37
C3SLB7_ECOLX glmU Bifunctional protein GlmU 4.596e-06 0.29
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 5.252e-06 0.28
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 5.557e-06 0.29
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 5.742e-06 0.50
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 6.947e-06 0.30
TSPO_RAT Tspo Translocator protein 7.947e-06 0.33
STE24_YEAST STE24 CAAX prenyl protease 1 8.37e-06 0.38
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 8.441e-06 0.39
RET4_HUMAN RBP4 Retinol-binding protein 4 8.797e-06 0.33

Suprofen

PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 3.442e-15 1.00
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 8.378e-11 1.00
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 3.293e-37 0.46
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 6.679e-32 0.46
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 4.468e-30 0.37
BLAB_BACCE Metallo-beta-lactamase type 2 3.959e-25 0.28
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 2.592e-24 0.46
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 3.398e-22 0.37
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 1.04e-20 0.46
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 3.542e-19 0.59
IL8_HUMAN CXCL8 Interleukin-8 8.187e-18 0.46
HELD_ECOLI helD DNA helicase IV 1.882e-17 0.33
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 2.774e-17 0.40
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.998e-15 0.46
SCAF_HHV2H UL26 Capsid scaffolding protein 2.565e-13 0.31
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 6.873e-13 0.33
LOX5_MOUSE Alox5 Arachidonate 5-lipoxygenase 6.398e-11 0.34
ALBU_BOVIN ALB Serum albumin 4.828e-10 0.46
PGH2_BOVIN PTGS2 Prostaglandin G/H synthase 2 1.122e-09 0.46
Q962Y6_SCHMA TGR Thioredoxin glutathione reductase 2.103e-09 0.35
KAT2A_HUMAN KAT2A Histone acetyltransferase KAT2A 3.025e-09 0.31
GATA4_MOUSE Gata4 Transcription factor GATA-4 3.283e-09 0.38
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 3.283e-09 0.38
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 3.765e-09 0.35
SCAF_EBVB9 Capsid scaffolding protein 4.279e-09 0.31
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 6.989e-09 0.32
CH10_HUMAN HSPE1 10 kDa heat shock protein, mitochondrial 8.292e-09 0.29
CH60_HUMAN HSPD1 60 kDa heat shock protein, mitochondrial 8.292e-09 0.29
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 8.846e-09 0.31
AL3A1_HUMAN ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 1.629e-08 0.35
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 1.709e-08 0.30
SCAF_HHV6U U53 Capsid scaffolding protein 3.186e-08 0.31
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 3.391e-08 0.35
SC6A5_RAT Slc6a5 Sodium- and chloride-dependent glycine transporter 2 3.766e-08 0.31
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 4.463e-08 0.32
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.206e-07 0.38
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 5.394e-07 0.46
KS6B2_HUMAN RPS6KB2 Ribosomal protein S6 kinase beta-2 6.257e-07 0.29
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 7.045e-07 0.29
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 9.318e-07 0.33
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 1.046e-06 0.62
BLA1_STEMA Metallo-beta-lactamase L1 type 3 1.819e-06 0.29
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 3.946e-06 0.29
Q2XUH7_PIG Angiotensin type II receptor 5.125e-06 0.35
Q7T1G6_DANRE trpn1 Ion channel NompC 6.484e-06 0.35
BLA2_BACCE blm Metallo-beta-lactamase type 2 8.279e-06 0.28
ALDH2_HUMAN ALDH2 Aldehyde dehydrogenase, mitochondrial 9.282e-06 0.35

Pemirolast

Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 5.218e-15 1.00
AGTR1_BOVIN AGTR1 Type-1 angiotensin II receptor 3.213e-10 0.38
PARE_STAAU parE DNA topoisomerase 4 subunit B 2.534e-08 0.29
AGTRB_RAT Agtr1b Type-1B angiotensin II receptor 1.717e-07 0.32
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 3.814e-06 0.36

Ketotifen

DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.021e-14 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 1.195e-06 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 3.142e-05 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 6.703e-05 1.00
HRH1_CAVPO HRH1 Histamine H1 receptor 0.0007954 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.001939 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 0.002681 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.004499 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 0.006825 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.009091 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.01978 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.01983 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.04655 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.05027 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.06149 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.141 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.1528 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.2438 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 0.4522 1.00
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 2.022e-38 0.49
DRD5_HUMAN DRD5 D(1B) dopamine receptor 2.654e-35 0.43
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 3.604e-18 0.46
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 1.199e-14 0.37
5HT2C_MOUSE Htr2c 5-hydroxytryptamine receptor 2C 1.46e-13 0.47
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 4.289e-13 0.46
HRH1_RAT Hrh1 Histamine H1 receptor 7.397e-12 0.47
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.363e-08 0.47
HRH4_RAT Hrh4 Histamine H4 receptor 2.037e-07 0.30
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 4.173e-07 0.62
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 4.905e-07 0.29
DRD4_HUMAN DRD4 D(4) dopamine receptor 6.957e-07 0.43
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 8.718e-07 0.47
Q9BEG3_BOVIN 5-lipoxygenase 9.143e-06 0.36

Methdilazine

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.053e-12 1.00
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 5.295e-113 0.44
PRIO_MOUSE Prnp Major prion protein 7.497e-47 0.37
DEF_STAAM def Peptide deformylase 6.968e-37 0.36
TYTR_TRYCR TPR Trypanothione reductase 2.086e-36 0.40
LYSC1_RAT Lyz1 Lysozyme C-1 3.098e-32 0.40
CALM_BOVIN CALM Calmodulin 1.61e-27 0.40
BGLR_RAT Gusb Beta-glucuronidase 6.482e-25 0.40
EBPL_HUMAN EBPL Emopamil-binding protein-like 6.482e-25 0.40
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 7.742e-22 0.37
CALM1_HUMAN CALM1 Calmodulin-1 1.176e-20 0.40
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 1.202e-19 0.32
CHLE_HUMAN BCHE Cholinesterase 2.076e-19 0.40
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 2.22e-16 0.32
Q9IP65_HCMV US28 G protein-coupled receptor 5.551e-16 0.30
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 2.887e-15 0.31
HRH1_HUMAN HRH1 Histamine H1 receptor 7.661e-15 0.84
CHLE_HORSE BCHE Cholinesterase 1.055e-14 0.50
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 7.616e-14 0.84
NOX1_HUMAN NOX1 NADPH oxidase 1 1.045e-13 0.36
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 1.116e-12 0.35
Q9WTR4_RAT Slc6a2 Transporter 4.288e-12 0.33
US28_HCMVA US28 G-protein coupled receptor homolog US28 2.665e-11 0.30
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 3.21e-11 0.36
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 5.306e-11 0.31
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 8.636e-11 0.34
MALT1_HUMAN MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 1.326e-10 0.84
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 2.728e-10 0.84
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 4.395e-10 0.33
HRH2_HUMAN HRH2 Histamine H2 receptor 5.712e-10 0.44
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 1.125e-09 0.30
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 2.182e-09 0.84
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 4.317e-09 0.84
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 4.91e-09 0.32
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 2.945e-07 0.44
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 5.271e-07 0.37
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.331e-06 0.36
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.735e-06 0.84
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 1.908e-06 0.84
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.496e-06 0.84
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 2.587e-06 0.37
PRIO_HUMAN PRNP Major prion protein 2.923e-06 0.44
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 3.213e-06 0.28
DRD1_RAT Drd1 D(1A) dopamine receptor 6.551e-06 0.37
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 6.646e-06 0.84
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 7.872e-06 0.84
DRD1_HUMAN DRD1 D(1A) dopamine receptor 8.866e-06 0.44

Levamisole

PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 2.589e-12 1.00
PPBT_MOUSE Alpl Alkaline phosphatase, tissue-nonspecific isozyme 1.151e-134 0.72
CP2B6_HUMAN CYP2B6 Cytochrome P450 2B6 1.267e-36 0.30
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 2.718e-07 0.30

Zalcitabine

Q72547_9HIV1 pol Reverse transcriptase/RNaseH 1.598e-08 1.00
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 0.01803 1.00
ISPE_ECOLI ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1.361e-42 0.34
DPOLB_HUMAN POLB DNA polymerase beta 5.029e-35 0.61
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 5.442e-26 0.44
ADA_MOUSE Ada Adenosine deaminase 4.212e-24 0.30
KITH_VZVD TK Thymidine kinase 2.658e-19 0.29
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 2.975e-19 0.48
O39930_9HEPC NS5b RNA-directed RNA polymerase 1.674e-13 0.42
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.569e-12 0.69
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 3.832e-12 0.35
V5TFZ2_9FLAV Nonstructural protein 5 5.263e-12 0.32
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 3.779e-09 0.44
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 1.134e-08 0.29
CDD_MOUSE Cda Cytidine deaminase 2.871e-07 0.30
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 7.235e-07 0.32
CDD_HUMAN CDA Cytidine deaminase 1.777e-06 0.30
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 5.32e-06 0.38

Oxybuprocaine

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 5.407e-08 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.0009096 1.00
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 1.203e-74 0.43
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.625e-74 0.39
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 5.683e-67 0.32
AMYP_RAT Amy2 Pancreatic alpha-amylase 6.539e-57 0.38
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 3.047e-52 0.53
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 7.542e-50 0.35
ERG1_RAT Sqle Squalene monooxygenase 1.134e-43 0.38
AGTR1_PIG AGTR1 Type-1 angiotensin II receptor 2.271e-40 0.31
TLR1_HUMAN TLR1 Toll-like receptor 1 1.921e-39 0.31
THA_HUMAN THRA Thyroid hormone receptor alpha 1.82e-32 0.39
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 6.838e-31 0.42
Q8WMX0_BOVIN Muscarinic receptor M1 7.565e-30 0.38
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 5.637e-29 0.44
TLR1_MOUSE Tlr1 Toll-like receptor 1 6.079e-29 0.34
TLR2_MOUSE Tlr2 Toll-like receptor 2 6.079e-29 0.34
REV_HV1W2 rev Protein Rev 3.829e-28 0.35
ERG2_YEAST ERG2 C-8 sterol isomerase 3.662e-27 0.42
THB_HUMAN THRB Thyroid hormone receptor beta 1.685e-25 0.39
KDM6A_HUMAN KDM6A Lysine-specific demethylase 6A 5.379e-25 0.31
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 8.073e-25 0.39
IKKB_MOUSE Ikbkb Inhibitor of nuclear factor kappa-B kinase subunit beta 1.988e-21 0.31
MDHM_HUMAN MDH2 Malate dehydrogenase, mitochondrial 2.137e-20 0.34
RARB_HUMAN RARB Retinoic acid receptor beta 7.626e-18 0.35
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 1.11e-16 0.37
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 3.331e-16 0.36
HNF4A_RAT Hnf4a Hepatocyte nuclear factor 4-alpha 3.442e-15 0.32
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.776e-14 0.37
ACRO_PIG ACR Acrosin 4.53e-14 0.29
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 2.893e-13 0.30
A3KMY8_BOVIN GUSB Beta-glucuronidase 2.959e-13 0.31
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 4.33e-13 0.34
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 8.045e-13 0.45
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 1.076e-12 0.38
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.128e-12 0.39
RARA_HUMAN RARA Retinoic acid receptor alpha 1.859e-12 0.35
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 2.186e-12 0.30
HNF4A_HUMAN HNF4A Hepatocyte nuclear factor 4-alpha 2.406e-12 0.32
RARG_HUMAN RARG Retinoic acid receptor gamma 8.906e-12 0.35
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 1.121e-11 0.35
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 1.17e-11 0.28
DCOR_MOUSE Odc1 Ornithine decarboxylase 2.119e-11 0.31
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 3.544e-11 0.29
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 4.107e-11 0.43
B4URF0_I33A0 Neuraminidase 8.114e-11 0.41
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.258e-10 0.32
ACRO_HUMAN ACR Acrosin 3.29e-10 0.35
Q4Q5W4_LEIMA Putative squalene synthase 6.32e-10 0.29
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 1.579e-09 0.38
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 1.735e-09 0.43
B2LA1_MOUSE Bcl2a1 Bcl-2-related protein A1 1.741e-09 0.35
RXRA_HUMAN RXRA Retinoic acid receptor RXR-alpha 1.856e-09 0.36
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.435e-09 0.39
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 3.496e-09 0.35
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 4.947e-09 0.48
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 5.106e-09 0.32
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 5.213e-09 0.31
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 8.452e-09 0.30
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 2.111e-08 0.35
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 2.536e-08 0.32
STS_HUMAN STS Steryl-sulfatase 3.632e-08 0.40
DYR_CHICK DHFR Dihydrofolate reductase 3.882e-08 0.31
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 4.014e-08 0.35
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 6.82e-08 0.31
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 8.39e-08 0.38
ALK_HUMAN ALK ALK tyrosine kinase receptor 8.773e-08 0.33
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.061e-07 0.43
Q43570_TOBAC NtBBF1.1 Zn finger protein 1.07e-07 0.32
PLM2_PLAFA Plasmepsin-2 1.09e-07 0.35
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.815e-07 0.43
CHLE_HORSE BCHE Cholinesterase 2.287e-07 0.34
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 2.656e-07 0.35
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.41e-07 0.39
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 4.405e-07 0.30
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 5.207e-07 0.33
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 5.533e-07 0.28
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 6.357e-07 0.48
TLR7_HUMAN TLR7 Toll-like receptor 7 6.584e-07 0.31
NORA_STAAU norA Quinolone resistance protein NorA 1.017e-06 0.33
SCN3A_HUMAN SCN3A Sodium channel protein type 3 subunit alpha 1.284e-06 0.43
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 1.498e-06 0.42
PLEC_HUMAN PLEC Plectin 2.186e-06 0.35
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 3.989e-06 0.31
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 4.225e-06 0.29
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 5.567e-06 0.28
AGP1_YEAST AGP1 General amino acid permease AGP1 7.85e-06 0.28
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 8.152e-06 0.29
HRH2_HUMAN HRH2 Histamine H2 receptor 8.272e-06 0.32
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 8.948e-06 0.43

Maprotiline

HRH1_HUMAN HRH1 Histamine H1 receptor 1.116e-06 1.00
DRD5_HUMAN DRD5 D(1B) dopamine receptor 1.009e-05 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.0002172 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 0.0002947 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.002182 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 0.002212 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 0.009014 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.01743 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 0.04204 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 0.05109 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 0.06101 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.1002 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.1054 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.3224 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.3402 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.4773 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.4877 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.5554 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.5947 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.6272 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.7266 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.8223 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.9777 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.9947 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 0.9999 1.00
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 5.16e-30 0.33
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 5.633e-25 0.33
Q9WTR4_RAT Slc6a2 Transporter 8.103e-10 0.40
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 3.997e-08 0.32
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 3.569e-07 0.32
Q63380_RAT NET Transporter 2.926e-06 0.32
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 4.194e-06 0.32
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 5.966e-06 0.40

Triazolam

GBRA1_HUMAN GABRA1 Gamma-aminobutyric acid receptor subunit alpha-1 7.421e-06 1.00
GBRA5_HUMAN GABRA5 Gamma-aminobutyric acid receptor subunit alpha-5 0.0002658 1.00
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 2.064e-82 0.81
AURKA_MOUSE Aurka Aurora kinase A 9.659e-15 0.32
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 3.776e-12 0.42
SC6A5_RAT Slc6a5 Sodium- and chloride-dependent glycine transporter 2 5.245e-12 0.35
DHI1_MOUSE Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 1.626e-10 0.35
SC6A9_RAT Slc6a9 Sodium- and chloride-dependent glycine transporter 1 8.803e-10 0.35
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 5.654e-08 0.55
TAT_HV112 tat Protein Tat 1.359e-06 0.29

Felbamate

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.229e-05 1.00
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 2.435e-57 0.33
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 1.354e-53 0.30
KYNU_HUMAN KYNU Kynureninase 1.04e-51 0.31
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 8.275e-48 0.33
GLT_PYRHO Glutamate transporter homolog 5.166e-42 0.33
CERT_HUMAN CERT1 Ceramide transfer protein 1.921e-39 0.31
KYNU_RAT Kynu Kynureninase 4.474e-39 0.31
GPR88_MOUSE Gpr88 Probable G-protein coupled receptor 88 1.917e-37 0.30
Q8VH25_CAVPO GPM4 Muscarinic acetylcholine receptor 3.56e-37 0.29
MURI_LACFE murI Glutamate racemase 1.572e-36 0.29
ACER2_HUMAN ACER2 Alkaline ceramidase 2 9.362e-36 0.28
NCS1_HUMAN NCS1 Neuronal calcium sensor 1 9.362e-36 0.28
Q9VWX8_DROME Frq2 FI18190p1 9.362e-36 0.28
BLAB_BACCE Metallo-beta-lactamase type 2 2.708e-35 0.40
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 6.48e-33 0.43
EST1_RABIT Liver carboxylesterase 1 1.408e-32 0.39
NK1R_RAT Tacr1 Substance-P receptor 1.211e-31 0.38
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 1.785e-25 0.38
Q43014_PRUAV Beta-glucosidase 1.418e-24 0.30
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 2.158e-24 0.30
KLK2_HUMAN KLK2 Kallikrein-2 7.729e-24 0.31
GABR2_RAT Gabbr2 Gamma-aminobutyric acid type B receptor subunit 2 3.991e-23 0.34
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 8.363e-23 0.35
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 1.507e-22 0.33
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.935e-22 0.33
KLK8_HUMAN KLK8 Kallikrein-8 1.271e-21 0.31
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 4.77e-21 0.34
MANR_PSEPU mdlA Mandelate racemase 6.654e-21 0.33
KCNN4_HUMAN KCNN4 Intermediate conductance calcium-activated potassium channel protein 4 2.493e-20 0.32
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 2.537e-20 0.34
EPHB_MYCTO Epoxide hydrolase B 2.952e-20 0.32
ACE_MOUSE Ace Angiotensin-converting enzyme 4.358e-20 0.30
KLK4_HUMAN KLK4 Kallikrein-4 7.122e-20 0.31
CBPA1_BOVIN CPA1 Carboxypeptidase A1 1.667e-19 0.35
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 3.08e-19 0.33
AOC3_HUMAN AOC3 Membrane primary amine oxidase 9.507e-19 0.35
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 2.309e-18 0.31
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.066e-17 0.33
PA_I34A1 PA Polymerase acidic protein 1.819e-17 0.32
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 1.882e-17 0.33
PA_I000X PA Polymerase acidic protein 1.11e-16 0.32
EST2_HUMAN CES2 Cocaine esterase 2.22e-16 0.39
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 4.441e-16 0.31
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 1.554e-15 0.34
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 1.665e-15 0.30
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 2.109e-15 0.33
PPAP_HUMAN ACP3 Prostatic acid phosphatase 2.331e-15 0.30
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 3.109e-15 0.29
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 4.663e-15 0.38
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 6.217e-15 0.30
CBPB1_PIG CPB1 Carboxypeptidase B 7.661e-15 0.34
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 2.509e-14 0.31
NEP_MOUSE Mme Neprilysin 3.697e-14 0.31
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 6.761e-14 0.31
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 9.504e-14 0.30
BLA2_BACCE blm Metallo-beta-lactamase type 2 1.364e-13 0.40
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.752e-13 0.35
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 4.238e-13 0.32
GLSK_HUMAN GLS Glutaminase kidney isoform, mitochondrial 5.329e-13 0.33
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 1.608e-12 0.31
AMPN_PIG ANPEP Aminopeptidase N 1.761e-12 0.36
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 5.486e-12 0.33
GPR88_HUMAN GPR88 Probable G-protein coupled receptor 88 6.776e-12 0.31
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 7.538e-12 0.33
EST1_HUMAN CES1 Liver carboxylesterase 1 1.138e-11 0.39
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 1.74e-11 0.35
FNTA_HUMAN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 4.085e-11 0.33
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 6.878e-11 0.29
AMPN_HUMAN ANPEP Aminopeptidase N 1.516e-10 0.33
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 2.375e-10 0.35
AMPL_PIG LAP3 Cytosol aminopeptidase 6.028e-10 0.28
MCA2_TRYBB MCA2 Metacaspase 6.171e-10 0.29
GALR2_RAT Galr2 Galanin receptor type 2 7.541e-10 0.29
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 8.203e-10 0.33
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 8.668e-10 0.31
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 1.863e-09 0.30
Q8WMX0_BOVIN Muscarinic receptor M1 3.13e-09 0.32
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 3.409e-09 0.46
Q9SEH8_SOYBN Man1 alpha-1,2-Mannosidase 3.598e-09 0.29
BLAB_AERHY cphA Metallo-beta-lactamase type 2 4.608e-09 0.28
Q8WSF8_APLCA Soluble acetylcholine receptor 7.092e-09 0.29
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 1.025e-08 0.35
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 1.069e-08 0.30
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.834e-08 0.30
DXR_ECOLI dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.913e-08 0.31
NK1R_HUMAN TACR1 Substance-P receptor 2.034e-08 0.37
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 2.739e-08 0.30
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 3.049e-08 0.39
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 3.077e-08 0.31
FEN1_HUMAN FEN1 Flap endonuclease 1 3.707e-08 0.30
MDM4_HUMAN MDM4 Protein Mdm4 3.883e-08 0.31
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 8.352e-08 0.29
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 1.27e-07 0.34
AMPL_HUMAN LAP3 Cytosol aminopeptidase 1.395e-07 0.30
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.507e-07 0.38
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 1.619e-07 0.33
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.706e-07 0.39
Q17SB2_PLAFA Plasmepsin 4 1.721e-07 0.29
CBPA1_HUMAN CPA1 Carboxypeptidase A1 2.373e-07 0.30
DXR_MYCTU dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3.054e-07 0.33
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 3.459e-07 0.38
UPAR_HUMAN PLAUR Urokinase plasminogen activator surface receptor 4.055e-07 0.29
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 4.078e-07 0.34
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 4.177e-07 0.29
VKOR1_RAT Vkorc1 Vitamin K epoxide reductase complex subunit 1 4.177e-07 0.29
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 4.28e-07 0.39
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 4.306e-07 0.31
CASR_HUMAN CASR Extracellular calcium-sensing receptor 4.383e-07 0.33
ACRO_HUMAN ACR Acrosin 4.721e-07 0.33
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 5.865e-07 0.30
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 6.416e-07 0.32
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 6.508e-07 0.40
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 6.864e-07 0.34
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 8.892e-07 0.33
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 9.396e-07 0.29
UROK_HUMAN PLAU Urokinase-type plasminogen activator 9.434e-07 0.31
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 1.574e-06 0.33
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 1.643e-06 0.30
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.085e-06 0.39
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 2.726e-06 0.30
NR1H4_MOUSE Nr1h4 Bile acid receptor 4.01e-06 0.29
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 4.685e-06 0.31
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 4.749e-06 0.30
GRM3_HUMAN GRM3 Metabotropic glutamate receptor 3 4.913e-06 0.38
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 5.9e-06 0.29
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 8.325e-06 0.37
ACHP_LYMST Acetylcholine-binding protein 8.718e-06 0.29

Alprenolol

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 9.618e-05 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.03885 1.00
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 2.28e-123 0.61
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 7.519e-111 0.69
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 6.258e-109 0.71
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 8.3e-98 0.60
ADRB2_MOUSE Adrb2 Beta-2 adrenergic receptor 3.044e-70 0.37
DNMT1_MOUSE Dnmt1 DNA (cytosine-5)-methyltransferase 1 1.86e-41 0.41
CASR_BOVIN CASR Extracellular calcium-sensing receptor 1.157e-39 0.31
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 1.967e-36 0.60
NAT_MYCSM nat Arylamine N-acetyltransferase 2.095e-36 0.29
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 7.885e-36 0.36
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 1.581e-31 0.60
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.826e-28 0.39
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 3.894e-27 0.60
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 2.395e-24 0.60
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.058e-21 0.60
SYFA_HAEIN pheS Phenylalanine--tRNA ligase alpha subunit 9.056e-18 0.28
SYFA_STRPN pheS Phenylalanine--tRNA ligase alpha subunit 9.056e-18 0.28
FDFT_RAT Fdft1 Squalene synthase 1.616e-17 0.68
CASR_HUMAN CASR Extracellular calcium-sensing receptor 2.22e-16 0.38
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 3.275e-14 0.29
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 1.704e-13 0.29
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 9.112e-11 0.29
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 1.511e-07 0.29
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 6.509e-07 0.60
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 7.784e-07 0.31
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 5.33e-06 0.43

Hexafluronium

Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 0.0006859 1.00
ACES_ELEEL ache Acetylcholinesterase 0.9235 1.00
ACM2_PIG CHRM2 Muscarinic acetylcholine receptor M2 2.627e-71 0.41
KCNK2_RAT Kcnk2 Potassium channel subfamily K member 2 5.239e-40 0.32
ACHB_TETCF CHRNB1 Acetylcholine receptor subunit beta 4.849e-25 0.30
ACHG_TETCF CHRNG Acetylcholine receptor subunit gamma 4.849e-25 0.30
ACHD_TETCF chrnd Acetylcholine receptor subunit delta 2.656e-22 0.30
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 1.11e-15 0.30
LUXR_ALIFS luxR Transcriptional activator protein LuxR 4.403e-11 0.32
FAS_RAT Fasn Fatty acid synthase 5.033e-11 0.29
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.526e-07 0.35
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 3.862e-06 0.35

Clofazimine

CYSP_TRYCR Cruzipain 0.005709 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.2687 1.00
STRP_STRP1 ska Streptokinase A 0.4152 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.5021 1.00
MSRA_BOVIN MSRA Mitochondrial peptide methionine sulfoxide reductase 4.119e-31 0.32
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 2.275e-30 0.39
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 6.284e-14 0.35
HMOX2_RAT Hmox2 Heme oxygenase 2 5.908e-09 0.30
GBB1_HUMAN GNB1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 1.023e-06 0.28
GBG2_HUMAN GNG2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 1.023e-06 0.28
DPOL_VACCW POL DNA polymerase 1.851e-06 0.32

Bimatoprost

AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 0.01157 1.00
PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 1.202e-171 0.72
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 6.914e-152 0.81
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 5.878e-97 0.61
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 5.738e-83 0.61
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 1.06e-82 0.61
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 1.062e-73 0.61
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 3.254e-65 0.49
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 1.732e-54 0.49
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 3.096e-49 0.61
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 1.154e-48 0.34
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 7.485e-48 0.49
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 3.779e-46 0.49
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 9.4e-37 0.64
ACER2_HUMAN ACER2 Alkaline ceramidase 2 1.195e-36 0.29
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.223e-32 0.61
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 2.229e-29 0.81
PE2R4_RABIT PTGER4 Prostaglandin E2 receptor EP4 subtype 8.943e-25 0.30
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 3.963e-24 0.41
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 6.251e-24 0.51
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 4.391e-22 0.61
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 5.481e-22 0.35
CNR1_RAT Cnr1 Cannabinoid receptor 1 1.299e-20 0.60
Q6UB75_PIG Group VII phospholipase A2 7.615e-20 0.30
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 9.296e-20 0.43
PI2R_HUMAN PTGIR Prostacyclin receptor 3.072e-19 0.43
GLCM_MOUSE Gba Lysosomal acid glucosylceramidase 5.986e-19 0.30
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 1.658e-17 0.29
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 2.256e-17 0.33
TA2R_RAT Tbxa2r Thromboxane A2 receptor 5.551e-16 0.47
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 1.221e-15 0.36
AMP1_PLAFQ M1 family aminopeptidase 1.332e-15 0.29
LPAR1_MOUSE Lpar1 Lysophosphatidic acid receptor 1 2.554e-15 0.29
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.932e-14 0.43
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 3.975e-14 0.61
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 9.559e-14 0.36
ACE_HUMAN ACE Angiotensin-converting enzyme 1.515e-13 0.31
MMP3_HUMAN MMP3 Stromelysin-1 3.387e-13 0.33
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 5.641e-13 0.28
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 1.214e-12 0.36
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 8.017e-12 0.29
ACE_RAT Ace Angiotensin-converting enzyme 1.476e-11 0.30
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 2.683e-11 0.34
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 3.102e-10 0.32
PPCE_BOVIN PREP Prolyl endopeptidase 8.149e-10 0.31
Q9NAW4_PLAFA Cysteine protease falcipain-3 8.577e-10 0.28
SCYD_MAGO7 SDH1 Scytalone dehydratase 4.584e-09 0.31
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.009e-08 0.38
DLG4_HUMAN DLG4 Disks large homolog 4 3.328e-08 0.30
CBPA1_BOVIN CPA1 Carboxypeptidase A1 4.098e-08 0.29
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 4.42e-08 0.30
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 8.451e-08 0.43
LYAM3_HUMAN SELP P-selectin 8.906e-08 0.32
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 1.436e-07 0.35
MMP2_HUMAN MMP2 72 kDa type IV collagenase 1.972e-07 0.33
CBPB1_PIG CPB1 Carboxypeptidase B 5.363e-07 0.28
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 5.368e-07 0.34
ACE_MOUSE Ace Angiotensin-converting enzyme 5.904e-07 0.28
MMP8_HUMAN MMP8 Neutrophil collagenase 8.485e-07 0.32
GPR18_HUMAN GPR18 N-arachidonyl glycine receptor 8.63e-07 0.31
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 8.672e-07 0.31
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 8.676e-07 0.30
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 8.676e-07 0.30
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 8.676e-07 0.30
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 8.676e-07 0.30
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 8.676e-07 0.30
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 8.676e-07 0.30
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 8.676e-07 0.30
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 8.676e-07 0.30
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 8.676e-07 0.30
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 8.676e-07 0.30
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 8.676e-07 0.30
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 8.676e-07 0.30
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 8.676e-07 0.30
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 8.676e-07 0.30
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 8.676e-07 0.30
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 8.676e-07 0.30
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 8.676e-07 0.30
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 8.676e-07 0.30
PLM1_PLAFA Plasmepsin-1 8.92e-07 0.31
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.36e-06 0.32
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.864e-06 0.32
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 2.815e-06 0.32
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 3.254e-06 0.30
NEP_RAT Mme Neprilysin 3.999e-06 0.32
ACE_RABIT ACE Angiotensin-converting enzyme 4.427e-06 0.31
CMA1_HUMAN CMA1 Chymase 4.482e-06 0.32
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 4.993e-06 0.28
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 5.223e-06 0.29
HDA11_HUMAN HDAC11 Histone deacetylase 11 6.522e-06 0.33
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 7.53e-06 0.34
CATH_HUMAN CTSH Pro-cathepsin H 7.965e-06 0.30
GRIA4_RAT Gria4 Glutamate receptor 4 9.055e-06 0.31

Methantheline

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.06455 1.00
GRM7_HUMAN GRM7 Metabotropic glutamate receptor 7 5.014e-72 0.35
GRM8_HUMAN GRM8 Metabotropic glutamate receptor 8 1.47e-32 0.37
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 3.325e-29 0.30
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 7.207e-26 0.31
GRM3_RAT Grm3 Metabotropic glutamate receptor 3 2.199e-18 0.37
P2RX4_RAT P2rx4 P2X purinoceptor 4 2.528e-17 0.31
FFAR4_RAT Ffar4 Free fatty acid receptor 4 2.442e-15 0.29
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 5.884e-15 0.28
CCR1_MOUSE Ccr1 C-C chemokine receptor type 1 1.876e-14 0.32
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 6.814e-12 0.30
Q8WMX0_BOVIN Muscarinic receptor M1 1.285e-11 0.40
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 2.837e-11 0.33
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 1.402e-09 0.29
OPRX_RAT Oprl1 Nociceptin receptor 1.923e-07 0.29
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 3.102e-07 0.37
GRM1_RAT Grm1 Metabotropic glutamate receptor 1 3.71e-07 0.37
GRM6_RAT Grm6 Metabotropic glutamate receptor 6 4.771e-07 0.35
GRM3_HUMAN GRM3 Metabotropic glutamate receptor 3 3.693e-06 0.35
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 6.668e-06 0.31

Dacarbazine

PAX8_HUMAN PAX8 Paired box protein Pax-8 0.07099 1.00
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 0.789 1.00
GUAD_HUMAN GDA Guanine deaminase 6.608e-13 0.35
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 6.811e-07 0.38

Oxymetazoline

5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 0.3669 1.00
NISCH_RAT Nisch Nischarin 8.398e-30 0.38
CISD1_RAT Cisd1 CDGSH iron-sulfur domain-containing protein 1 1.114e-23 0.29
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.911e-22 0.37
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 8.288e-22 0.66
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 3.498e-19 0.37
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 9.553e-19 0.35
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 2.624e-18 0.35
NISCH_HUMAN NISCH Nischarin 6.661e-16 0.33
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 1.188e-14 0.36
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 5.251e-14 0.35
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 9.008e-11 0.66
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 1.104e-09 0.66
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 3.664e-06 0.50
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 4.596e-06 0.29
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 7.112e-06 0.29

Dienestrol

CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.6612 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.8816 1.00
O87171_SPHPI lsdA Dioxygenase 9.035e-66 0.41
SSDH_HUMAN ALDH5A1 Succinate-semialdehyde dehydrogenase, mitochondrial 4.375e-53 0.42
GABT_HUMAN ABAT 4-aminobutyrate aminotransferase, mitochondrial 4.8e-34 0.42
Q86PR3_AEDAE SCP-2 Sterol carrier protein 2 1.248e-24 0.30
H9TVJ1_CHISP TyR1 4.212e-24 0.30
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 7.389e-23 0.38
CAH3_HUMAN CA3 Carbonic anhydrase 3 2.816e-18 0.43
MYG_HUMAN MB Myoglobin 1.882e-17 0.33
ESR1_HUMAN ESR1 Estrogen receptor 1.11e-16 0.52
Q2PCB5_DICLA ca Carbonic anhydrase 7.772e-16 0.43
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 7.772e-16 0.31
ESR2_HUMAN ESR2 Estrogen receptor beta 1.665e-15 0.52
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 3.922e-13 0.29
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 1.331e-11 0.45
MTSI_SPISQ sssIM CPG DNA methylase 6.627e-11 0.34
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 1.441e-10 0.33
CAH15_MOUSE Ca15 Carbonic anhydrase 15 4.86e-09 0.43
MIF_HUMAN MIF Macrophage migration inhibitory factor 2.123e-08 0.31
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 4.951e-08 0.28
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 5.192e-08 0.28
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 9.455e-08 0.34
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 2.811e-07 0.36
CAH14_HUMAN CA14 Carbonic anhydrase 14 3.347e-07 0.43
A4_HUMAN APP Amyloid-beta precursor protein 4.004e-07 0.42
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 7.65e-07 0.40
O49150_SOLTU Lipoxygenase 9.875e-07 0.33
CAH7_HUMAN CA7 Carbonic anhydrase 7 1.023e-06 0.43
GABT_RAT Abat 4-aminobutyrate aminotransferase, mitochondrial 1.547e-06 0.34
AHR_RABIT AHR Aryl hydrocarbon receptor 1.71e-06 0.38
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 1.844e-06 0.38
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.858e-06 0.38
H9B8T9_CAPHI CTSB Cathepsin B 2.802e-06 0.37
CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 3.247e-06 0.36
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 4.704e-06 0.30
A0A060INS8_CAPHI CTSH Cathepsin H 5.348e-06 0.37

Ondansetron

KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.976 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.9903 1.00
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 7.425e-36 0.34
KGP1_BOVIN PRKG1 cGMP-dependent protein kinase 1 6.587e-33 0.33
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 7.231e-22 0.40
MYLK_CHICK Mylk Myosin light chain kinase, smooth muscle 1.513e-12 0.33
PDE6D_HUMAN PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 2.349e-11 0.34
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 4.09e-10 0.32
KAPCB_HUMAN PRKACB cAMP-dependent protein kinase catalytic subunit beta 1.665e-08 0.28
RB_HUMAN RB1 Retinoblastoma-associated protein 2.045e-08 0.35
TLK2_HUMAN TLK2 Serine/threonine-protein kinase tousled-like 2 4.951e-08 0.28
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 5.867e-07 0.37
PI51C_HUMAN PIP5K1C Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma 5.904e-07 0.28
TLK1_HUMAN TLK1 Serine/threonine-protein kinase tousled-like 1 5.904e-07 0.28
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 1.211e-06 0.29
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 1.995e-06 0.28
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 2.849e-06 0.29
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 3.477e-06 0.62
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 8.279e-06 0.28
MYLK4_HUMAN MYLK4 Myosin light chain kinase family member 4 8.279e-06 0.28
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 9.122e-06 0.53

Paricalcitol

VDR_HUMAN VDR Vitamin D3 receptor 1.393e-206 0.65
VDR_RAT Vdr Vitamin D3 receptor 1.02e-202 0.65
VDR_BOVIN VDR Vitamin D3 receptor 3.31e-119 0.50
VDR_CHICK VDR Vitamin D3 receptor 7.247e-98 0.50
VDRA_DANRE vdra Vitamin D3 receptor A 3.046e-90 0.50
VDR_MOUSE Vdr Vitamin D3 receptor 2.475e-77 0.35
VDR_PIG VDR Vitamin D3 receptor 1.414e-62 0.50
VTDB_HUMAN GC Vitamin D-binding protein 1.414e-62 0.50
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1.328e-39 0.52
CRYAB_HUMAN CRYAB Alpha-crystallin B chain 5.448e-24 0.29
DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 2.208e-20 0.32
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 3.08e-12 0.39
ECR_DROME EcR Ecdysone receptor 3.186e-08 0.28
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 1.894e-06 0.29
NR1H4_MOUSE Nr1h4 Bile acid receptor 5.379e-06 0.28

Almotriptan

5HT1D_PIG HTR1D 5-hydroxytryptamine receptor 1D 6.572e-176 0.65
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 3.162e-142 0.65
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 5.454e-139 0.65
NK2R_RAT Tacr2 Substance-K receptor 6.479e-66 0.34
PERM_HUMAN MPO Myeloperoxidase 6.938e-57 0.51
Q8MI13_BOVIN 5htr1d 5-hydroxytryptamine 1D receptor 1.805e-50 0.65
SPRE_HUMAN SPR Sepiapterin reductase 5.96e-47 0.33
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 2.263e-36 0.65
SYUA_HUMAN SNCA Alpha-synuclein 9.11e-34 0.31
5HT1B_GORGO HTR1B 5-hydroxytryptamine receptor 1B 1.972e-33 0.65
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 5.734e-33 0.52
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 2.033e-30 0.41
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 1.859e-29 0.65
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 4.272e-28 0.65
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 3.22e-25 0.52
5HT1D_RAT Htr1d 5-hydroxytryptamine receptor 1D 6.235e-25 0.65
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 1.727e-24 0.53
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 7.938e-22 0.35
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 1.544e-20 0.65
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.56e-20 0.40
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 7.224e-20 0.65
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.328e-19 0.65
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.11e-16 0.39
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 2.089e-13 0.65
DRD2_RAT Drd2 D(2) dopamine receptor 1.389e-12 0.53
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 7.199e-12 0.65
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 4.953e-11 0.46
5HT5A_RAT Htr5a 5-hydroxytryptamine receptor 5A 9.74e-11 0.30
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.716e-10 0.65
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 7.085e-10 0.37
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 8.162e-10 0.65
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 1.337e-09 0.32
5HT6R_RAT Htr6 5-hydroxytryptamine receptor 6 8.722e-09 0.30
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 2.335e-08 0.65
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 1.608e-07 0.32
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 4.442e-07 0.29
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 9.859e-07 0.35
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.112e-06 0.31
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 1.386e-06 0.43
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 5.569e-06 0.32
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 8.404e-06 0.28
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 8.414e-06 0.53

Ranitidine

ACM1_MOUSE Chrm1 Muscarinic acetylcholine receptor M1 4.46e-174 0.64
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 6.012e-159 0.64
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 2.854e-22 0.55
QPCTL_HUMAN QPCTL Glutaminyl-peptide cyclotransferase-like protein 6.979e-19 0.32
CHLE_HUMAN BCHE Cholinesterase 3.331e-16 0.64
H6TY12_PERAM Nicotinic acetylcholine receptor alpha8 subunit 3.664e-15 0.39
ACES_HUMAN ACHE Acetylcholinesterase 1.353e-13 0.64
ACH4_DROME nAChRbeta2 Acetylcholine receptor subunit beta-like 2 4.806e-11 0.30
QPCT_HUMAN QPCT Glutaminyl-peptide cyclotransferase 2.061e-07 0.32
HRH2_RAT Hrh2 Histamine H2 receptor 8.687e-07 0.33
HRH2_CAVPO HRH2 Histamine H2 receptor 3.402e-06 0.45
ACES_ELEEL ache Acetylcholinesterase 3.5e-06 0.71

Conivaptan

V2R_RAT Avpr2 Vasopressin V2 receptor 6.496e-169 0.77
V2R_HUMAN AVPR2 Vasopressin V2 receptor 1.079e-161 0.77
V1AR_RAT Avpr1a Vasopressin V1a receptor 1.295e-136 0.77
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 1.157e-83 0.36
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 6.65e-80 0.77
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 3.867e-70 0.34
LIPL_BOVIN LPL Lipoprotein lipase 8.69e-56 0.31
PRIO_SHEEP PRNP Major prion protein 4.008e-49 0.34
M21_HRSVA M2-1 Matrix M2-1 4.604e-49 0.39
NCAP_HRSVA N Nucleoprotein 4.604e-49 0.39
PHOSP_HRSVA P Phosphoprotein 4.604e-49 0.39
COX1_SHEEP MT-CO1 Cytochrome c oxidase subunit 1 9.681e-38 0.30
TRPV1_CAVPO Trpv1 Transient receptor potential cation channel subfamily V member 1 2.333e-36 0.29
BAP1_HUMAN BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1 3.875e-36 0.29
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 3.643e-35 0.31
APOB_HUMAN APOB Apolipoprotein B-100 5.265e-30 0.34
O31272_9GAMM imiS Beta-lactamase 2.613e-27 0.30
CCKAR_RAT Cckar Cholecystokinin receptor type A 9.641e-26 0.36
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 4.495e-24 0.41
FSHR_RAT Fshr Follicle-stimulating hormone receptor 8.089e-24 0.29
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 5.444e-23 0.36
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.201e-22 0.32
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 9.738e-22 0.31
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 9.265e-19 0.32
AGTRA_RAT Agtr1 Type-1A angiotensin II receptor 1.872e-17 0.35
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 4.441e-16 0.32
CTNB1_HUMAN CTNNB1 Catenin beta-1 8.216e-15 0.32
AGTRB_RAT Agtr1b Type-1B angiotensin II receptor 1.599e-14 0.32
AGTR1_HUMAN AGTR1 Type-1 angiotensin II receptor 2.909e-14 0.36
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 5.018e-14 0.33
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 1.028e-13 0.32
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 5.283e-12 0.31
AGTR1_RABIT AGTR1 Type-1 angiotensin II receptor 2.017e-11 0.34
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 2.412e-11 0.30
SMO_HUMAN SMO Smoothened homolog 4.021e-11 0.38
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 1.081e-10 0.29
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 1.204e-10 0.31
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 6.413e-10 0.32
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 6.62e-10 0.29
FA10_HUMAN F10 Coagulation factor X 1.15e-09 0.37
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 1.316e-09 0.36
TPA_HUMAN PLAT Tissue-type plasminogen activator 2.622e-09 0.32
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 3.399e-09 0.29
OXYR_HUMAN OXTR Oxytocin receptor 3.818e-09 0.61
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 9.368e-09 0.34
FSHR_HUMAN FSHR Follicle-stimulating hormone receptor 1.09e-08 0.37
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 2.598e-08 0.32
P2Y14_MOUSE P2ry14 P2Y purinoceptor 14 2.634e-08 0.32
NR1H4_HUMAN NR1H4 Bile acid receptor 1.197e-07 0.36
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 1.336e-07 0.32
AURKA_HUMAN AURKA Aurora kinase A 1.377e-07 0.34
UROK_HUMAN PLAU Urokinase-type plasminogen activator 1.758e-07 0.40
GATA4_MOUSE Gata4 Transcription factor GATA-4 2.083e-07 0.30
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 2.083e-07 0.30
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 3.065e-07 0.36
OX2R_HUMAN HCRTR2 Orexin receptor type 2 6.326e-07 0.34
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 7.615e-07 0.31
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 9.396e-07 0.29
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 1.161e-06 0.31
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 1.341e-06 0.38
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.41e-06 0.34
MK14_RAT Mapk14 Mitogen-activated protein kinase 14 1.477e-06 0.33
SMO_MOUSE Smo Smoothened homolog 2.027e-06 0.33
SHH_MOUSE Shh Sonic hedgehog protein 2.378e-06 0.33
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.611e-06 0.29
OX1R_HUMAN HCRTR1 Orexin receptor type 1 3.477e-06 0.34
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 4.8e-06 0.32
GASR_CANLF CCKBR Gastrin/cholecystokinin type B receptor 4.902e-06 0.28
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 7.298e-06 0.39
HPSE_HUMAN HPSE Heparanase 8.073e-06 0.29
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 8.176e-06 0.28
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 8.403e-06 0.30

Metacycline

MDFA_ECOLI mdfA Multidrug transporter MdfA 1.089e-126 0.49

Benzonatate

CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 4.364e-126 0.68
ACRO_HUMAN ACR Acrosin 1.179e-59 0.42
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 9.521e-57 0.38
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.251e-43 0.33
ERG1_RAT Sqle Squalene monooxygenase 1.816e-38 0.37
TLR1_HUMAN TLR1 Toll-like receptor 1 4.265e-38 0.30
DYR_ENTFC folA Dihydrofolate reductase 3.03e-33 0.30
TLR1_MOUSE Tlr1 Toll-like receptor 1 2.699e-32 0.31
TLR2_MOUSE Tlr2 Toll-like receptor 2 2.699e-32 0.31
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 2.119e-25 0.33
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.785e-25 0.34
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 5.175e-25 0.28
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 7.187e-23 0.29
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 2.309e-21 0.33
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 2.374e-21 0.38
SMO_MOUSE Smo Smoothened homolog 1.857e-19 0.41
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 5.411e-19 0.36
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 5.363e-18 0.31
NADE_BACSU nadE NH(3)-dependent NAD(+) synthetase 6.375e-18 0.28
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 6.569e-18 0.31
PSBA_SPIOL psbA Photosystem II protein D1 9.809e-18 0.29
RARB_HUMAN RARB Retinoic acid receptor beta 1.563e-17 0.37
DHPS_ECOLI folP Dihydropteroate synthase 1.11e-16 0.40
RIR2_HUMAN RRM2 Ribonucleoside-diphosphate reductase subunit M2 1.11e-16 0.36
GATA4_MOUSE Gata4 Transcription factor GATA-4 1.443e-15 0.35
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 1.443e-15 0.35
MDHM_HUMAN MDH2 Malate dehydrogenase, mitochondrial 4.441e-15 0.29
TLR8_HUMAN TLR8 Toll-like receptor 8 4.774e-15 0.33
TLR7_HUMAN TLR7 Toll-like receptor 7 8.327e-15 0.36
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 1.765e-14 0.68
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 3.253e-14 0.38
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 3.533e-13 0.33
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 5.125e-13 0.28
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 2.046e-12 0.30
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.35e-12 0.30
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 2.898e-12 0.34
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 2.963e-12 0.32
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 5.743e-12 0.29
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 6.089e-12 0.33
EST2C_MOUSE Ces2c Acylcarnitine hydrolase 9.7e-12 0.29
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 2.648e-11 0.34
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 2.959e-11 0.31
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 3.172e-11 0.34
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 2.156e-10 0.33
Q4Q5W4_LEIMA Putative squalene synthase 3.022e-10 0.30
TRY1_HUMAN PRSS1 Trypsin-1 4.207e-10 0.42
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 4.664e-10 0.38
SCN3A_HUMAN SCN3A Sodium channel protein type 3 subunit alpha 5.287e-10 0.68
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 7.051e-10 0.39
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 8.267e-10 0.39
KCNH3_HUMAN KCNH3 Potassium voltage-gated channel subfamily H member 3 8.724e-10 0.30
CAH14_HUMAN CA14 Carbonic anhydrase 14 2.089e-09 0.36
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 2.232e-09 0.35
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 2.578e-09 0.43
A1ZA98_DROME Jhe Carboxylic ester hydrolase 3.598e-09 0.29
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 3.887e-09 0.34
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 3.906e-09 0.33
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 3.939e-09 0.29
RARA_HUMAN RARA Retinoic acid receptor alpha 4.272e-09 0.37
CAH2_HUMAN CA2 Carbonic anhydrase 2 5.924e-09 0.43
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 7.08e-09 0.29
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 7.406e-09 0.35
CAN2_PIG CAPN2 Calpain-2 catalytic subunit 1.052e-08 0.28
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 1.38e-08 0.29
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 1.493e-08 0.28
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 2.191e-08 0.31
AOC1_HUMAN AOC1 Amiloride-sensitive amine oxidase [copper-containing] 2.754e-08 0.29
STS_HUMAN STS Steryl-sulfatase 2.823e-08 0.42
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 4.652e-08 0.35
CAC1S_RAT Cacna1s Voltage-dependent L-type calcium channel subunit alpha-1S 6.98e-08 0.30
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 7.725e-08 0.36
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 9.826e-08 0.31
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.346e-07 0.30
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.558e-07 0.32
E3UJZ5_SPOLI Ecdysone receptor 1.598e-07 0.29
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 1.634e-07 0.33
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.64e-07 0.43
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.924e-07 0.33
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 2.192e-07 0.32
O61059_LEIME LmGT2 Glucose transporter 3.936e-07 0.43
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 4.314e-07 0.33
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 4.905e-07 0.29
HRH3_RAT Hrh3 Histamine H3 receptor 4.942e-07 0.36
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 5.065e-07 0.43
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 5.944e-07 0.33
CEL_BOVIN CEL Bile salt-activated lipase 6.322e-07 0.28
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 6.841e-07 0.31
CAH7_HUMAN CA7 Carbonic anhydrase 7 7.044e-07 0.36
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 7.791e-07 0.35
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 7.888e-07 0.68
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 8.103e-07 0.33
ALBU_HUMAN ALB Serum albumin 8.547e-07 0.29
PPO2_AGABI PPO2 Polyphenol oxidase 2 9.231e-07 0.41
Q8ST54_TRYCR HK Phosphotransferase 1.03e-06 0.30
AOC1_RAT Aoc1 Amiloride-sensitive amine oxidase [copper-containing] 1.054e-06 0.28
Q56D28_CAVPO CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells 1.122e-06 0.28
GYRB_MYCSM gyrB DNA gyrase subunit B 1.249e-06 0.30
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 1.278e-06 0.30
PRIO_SHEEP PRNP Major prion protein 1.385e-06 0.30
CAH13_HUMAN CA13 Carbonic anhydrase 13 1.409e-06 0.35
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.556e-06 0.30
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.618e-06 0.29
SENP7_HUMAN SENP7 Sentrin-specific protease 7 1.878e-06 0.41
GBRB_MUSDO Rdl Gamma-aminobutyric acid receptor subunit beta 2.044e-06 0.32
CAH6_HUMAN CA6 Carbonic anhydrase 6 2.072e-06 0.35
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 2.236e-06 0.43
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 2.279e-06 0.29
O97467_PLAFA ht1 Hexose transporter 1 2.415e-06 0.43
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 2.434e-06 0.33
DRD1_PIG DRD1 D(1A) dopamine receptor 4.247e-06 0.29
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 4.944e-06 0.43
CATK_HUMAN CTSK Cathepsin K 5.55e-06 0.37
CAH3_HUMAN CA3 Carbonic anhydrase 3 5.669e-06 0.35
LYOX_HUMAN LOX Protein-lysine 6-oxidase 7.112e-06 0.29
ECR_BOMMO EcR Ecdysone receptor 7.279e-06 0.32
PRTN3_HUMAN PRTN3 Myeloblastin 7.709e-06 0.32
MPIP2_MOUSE Cdc25b M-phase inducer phosphatase 2 7.85e-06 0.28
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 8.031e-06 0.29
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 8.269e-06 0.49
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 8.36e-06 0.43
Q8MWR1_SPOFR USP Ultraspiracle protein 8.827e-06 0.29
Q8MWR2_SPOFR EcR Ecdysteroid receptor 8.827e-06 0.29
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 9.56e-06 0.39

Mesoridazine

PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 8.822e-111 0.41
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 6.613e-64 0.34
PRIO_MOUSE Prnp Major prion protein 3.502e-48 0.38
TYTR_TRYCR TPR Trypanothione reductase 3.981e-41 0.43
LYSC1_RAT Lyz1 Lysozyme C-1 4.986e-31 0.38
CALM_BOVIN CALM Calmodulin 2.322e-27 0.38
BGLR_RAT Gusb Beta-glucuronidase 5.462e-24 0.38
EBPL_HUMAN EBPL Emopamil-binding protein-like 5.462e-24 0.38
ITAM_HUMAN ITGAM Integrin alpha-M 5.889e-23 0.28
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 1.512e-22 0.38
CALM1_HUMAN CALM1 Calmodulin-1 1.544e-20 0.38
HRH1_HUMAN HRH1 Histamine H1 receptor 3.821e-17 0.42
Q9IP65_HCMV US28 G protein-coupled receptor 5.662e-15 0.28
CHLE_HORSE BCHE Cholinesterase 1.132e-12 0.53
Q8MI13_BOVIN 5htr1d 5-hydroxytryptamine 1D receptor 2.95e-12 0.29
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 5.389e-12 0.42
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 2.022e-11 0.71
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 2.358e-11 0.30
DEF_STAAM def Peptide deformylase 4.214e-11 0.33
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 5.129e-11 0.30
NOX1_HUMAN NOX1 NADPH oxidase 1 6.486e-11 0.34
US28_HCMVA US28 G-protein coupled receptor homolog US28 1.309e-10 0.28
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 2.492e-10 0.38
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 5.559e-10 0.34
ACHA9_RAT Chrna9 Neuronal acetylcholine receptor subunit alpha-9 6.311e-10 0.31
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 8.871e-10 0.42
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 9.824e-10 0.39
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 1.822e-09 0.30
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 3.598e-09 0.29
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.428e-08 0.42
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 2.057e-08 0.30
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 2.35e-08 0.42
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 8.941e-08 0.42
HRH2_HUMAN HRH2 Histamine H2 receptor 1.359e-07 0.38
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.365e-07 0.28
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 2.241e-07 0.33
CHLE_HUMAN BCHE Cholinesterase 2.302e-07 0.40
CNR1_RAT Cnr1 Cannabinoid receptor 1 2.768e-07 0.33
ACHB2_RAT Chrnb2 Neuronal acetylcholine receptor subunit beta-2 2.804e-07 0.34
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 3.467e-07 0.38
ACHA4_RAT Chrna4 Neuronal acetylcholine receptor subunit alpha-4 4.331e-07 0.34
DRD1_HUMAN DRD1 D(1A) dopamine receptor 6.511e-07 0.71
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 6.78e-07 0.33
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 1.289e-06 0.33
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 1.68e-06 0.32
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 4.027e-06 0.32
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 4.211e-06 0.42
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 6.841e-06 0.39
PRIO_HUMAN PRNP Major prion protein 7.118e-06 0.40
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 8.172e-06 0.42
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 9.284e-06 0.30

Anileridine

S12A5_RAT Slc12a5 Solute carrier family 12 member 5 1.367e-109 0.37
NK2R_MOUSE Tacr2 Substance-K receptor 1.768e-71 0.35
CHLE_MOUSE Bche Cholinesterase 2.265e-65 0.35
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 6.125e-64 0.50
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 4.831e-60 0.46
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.799e-56 0.50
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 2.104e-51 0.38
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 6.163e-49 0.47
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 6.525e-45 0.48
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 1.474e-44 0.35
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 3.537e-42 0.35
UTS2_MACMU UTS2 Urotensin-2 1.332e-36 0.29
AGTRB_RAT Agtr1b Type-1B angiotensin II receptor 1.149e-35 0.33
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 3.867e-35 0.38
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 6.131e-35 0.47
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 3.284e-34 0.54
OPRD_HUMAN OPRD1 Delta-type opioid receptor 4.53e-34 0.48
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 1.697e-32 0.40
NK2R_BOVIN TACR2 Substance-K receptor 6.21e-32 0.32
OPRM_HUMAN OPRM1 Mu-type opioid receptor 3.372e-30 0.66
DCMC_MOUSE Mlycd Malonyl-CoA decarboxylase, mitochondrial 6.625e-29 0.33
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 1.044e-27 0.31
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 1.154e-27 0.36
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 1.285e-27 0.33
THYX_PBCV1 Probable flavin-dependent thymidylate synthase 1.293e-27 0.33
OPRM_RAT Oprm1 Mu-type opioid receptor 1.624e-26 0.48
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 9.039e-26 0.66
GHRHR_RAT Ghrhr Growth hormone-releasing hormone receptor 6.289e-24 0.30
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 8.472e-24 0.31
NK2R_RAT Tacr2 Substance-K receptor 1.116e-23 0.35
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 2.614e-23 0.38
PDIA1_HUMAN P4HB Protein disulfide-isomerase 2.697e-23 0.39
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 4.185e-23 0.28
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 4.696e-22 0.38
EBPL_HUMAN EBPL Emopamil-binding protein-like 7.378e-22 0.35
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 1.089e-21 0.38
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.214e-21 0.38
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 2.977e-21 0.54
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 4.227e-21 0.39
US28_HCMVA US28 G-protein coupled receptor homolog US28 2.073e-20 0.29
OPRX_HUMAN OPRL1 Nociceptin receptor 2.074e-20 0.41
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 5.61e-20 0.32
DRD2_BOVIN DRD2 D(2) dopamine receptor 6.31e-19 0.41
DRD2_HUMAN DRD2 D(2) dopamine receptor 6.651e-19 0.45
Q63380_RAT NET Transporter 1.645e-18 0.46
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.703e-18 0.39
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 2.494e-18 0.32
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 3.294e-18 0.41
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 3.916e-18 0.38
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 5.218e-18 0.38
DRD2_RAT Drd2 D(2) dopamine receptor 2.665e-17 0.41
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 3.969e-17 0.54
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 4.514e-17 0.35
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 4.931e-17 0.32
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.11e-16 0.45
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.22e-16 0.39
NK2R_HUMAN TACR2 Substance-K receptor 2.22e-16 0.37
NK3R_HUMAN TACR3 Neuromedin-K receptor 3.331e-16 0.34
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 5.551e-16 0.31
HRH1_HUMAN HRH1 Histamine H1 receptor 6.661e-16 0.38
ADA1B_MOUSE Adra1b Alpha-1B adrenergic receptor 9.992e-16 0.30
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 9.992e-16 0.38
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 1.332e-15 0.45
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 1.665e-15 0.35
PA_I000X PA Polymerase acidic protein 2.109e-15 0.29
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.665e-15 0.42
NK1R_CAVPO TACR1 Substance-P receptor 2.665e-15 0.35
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 4.885e-15 0.48
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 4.885e-15 0.51
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 9.659e-15 0.35
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 9.992e-15 0.37
SOAT1_HUMAN SOAT1 Sterol O-acyltransferase 1 1.01e-14 0.33
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.465e-14 0.66
DRD3_HUMAN DRD3 D(3) dopamine receptor 3.642e-14 0.45
HRH3_RAT Hrh3 Histamine H3 receptor 3.875e-14 0.36
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 6.861e-14 0.38
CAC1D_HUMAN CACNA1D Voltage-dependent L-type calcium channel subunit alpha-1D 3.164e-13 0.29
VACHT_TETCF Vesicular acetylcholine transporter 3.779e-13 0.36
OGA_RAT Oga Protein O-GlcNAcase 3.922e-13 0.29
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 4.121e-13 0.38
HRH2_HUMAN HRH2 Histamine H2 receptor 5.018e-13 0.32
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 5.046e-13 0.41
OPRM_CAVPO OPRM1 Mu-type opioid receptor 5.747e-13 0.66
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 1.288e-12 0.31
DRD2_MOUSE Drd2 D(2) dopamine receptor 1.626e-12 0.33
VACHT_RAT Slc18a3 Vesicular acetylcholine transporter 1.722e-12 0.35
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 2.032e-12 0.38
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 3.336e-12 0.30
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 3.78e-12 0.37
HRH3_HUMAN HRH3 Histamine H3 receptor 7.527e-12 0.40
AGTR1_BOVIN AGTR1 Type-1 angiotensin II receptor 1.374e-11 0.33
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 1.381e-11 0.44
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 1.608e-11 0.32
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 1.92e-11 0.31
KCNJ1_HUMAN KCNJ1 ATP-sensitive inward rectifier potassium channel 1 2.179e-11 0.42
ACE_HUMAN ACE Angiotensin-converting enzyme 2.222e-11 0.34
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 2.342e-11 0.37
OPRD_RAT Oprd1 Delta-type opioid receptor 3.24e-11 0.48
CALM_BOVIN CALM Calmodulin 3.542e-11 0.30
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 4.205e-11 0.29
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 4.265e-11 0.66
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 6.946e-11 0.47
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 7.961e-11 0.33
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 9.364e-11 0.41
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 1.133e-10 0.42
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 1.517e-10 0.31
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 2.067e-10 0.41
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 2.578e-10 0.32
NK1R_HUMAN TACR1 Substance-P receptor 6.779e-10 0.37
GYRB_MYCSM gyrB DNA gyrase subunit B 7.109e-10 0.32
RARB_HUMAN RARB Retinoic acid receptor beta 9.473e-10 0.30
ACES_MOUSE Ache Acetylcholinesterase 1.009e-09 0.35
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.448e-09 0.32
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 2.075e-09 0.32
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 2.23e-09 0.33
Q8WSF8_APLCA Soluble acetylcholine receptor 2.491e-09 0.30
NORA_STAAU norA Quinolone resistance protein NorA 2.704e-09 0.32
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 2.873e-09 0.31
P2RX1_MOUSE P2rx1 P2X purinoceptor 1 3.055e-09 0.29
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 3.327e-09 0.33
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 4.307e-09 0.32
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 5.161e-09 0.76
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 6.156e-09 0.34
NK3R_CAVPO TACR3 Neuromedin-K receptor 6.798e-09 0.34
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 8.779e-09 0.34
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 1.036e-08 0.29
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 1.039e-08 0.33
BRS3_MOUSE Brs3 Bombesin receptor subtype-3 1.101e-08 0.30
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 2.83e-08 0.39
DRD3_CHLAE DRD3 D(3) dopamine receptor 4.521e-08 0.28
FSHR_HUMAN FSHR Follicle-stimulating hormone receptor 4.662e-08 0.32
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 5.683e-08 0.38
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 6.101e-08 0.30
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 6.532e-08 0.32
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 9.688e-08 0.35
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 1.319e-07 0.38
ADAM9_HUMAN ADAM9 Disintegrin and metalloproteinase domain-containing protein 9 1.693e-07 0.31
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2.011e-07 0.35
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 2.934e-07 0.33
PA_I34A1 PA Polymerase acidic protein 3.965e-07 0.29
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 4.483e-07 0.43
PLM2_PLAFA Plasmepsin-2 4.943e-07 0.36
MGLL_RAT Mgll Monoglyceride lipase 5.529e-07 0.29
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 9.403e-07 0.30
POLG_DEN2P Genome polyprotein 1.032e-06 0.28
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 1.922e-06 0.33
LMBL3_HUMAN L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 2.312e-06 0.31
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 2.318e-06 0.30
CASP5_HUMAN CASP5 Caspase-5 2.444e-06 0.31
PRIO_SHEEP PRNP Major prion protein 2.587e-06 0.29
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 2.971e-06 0.42
OPRM_MOUSE Oprm1 Mu-type opioid receptor 3.517e-06 0.54
NOS1_RAT Nos1 Nitric oxide synthase, brain 4.523e-06 0.38
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 4.86e-06 0.32
CCR5_MACFA CCR5 C-C chemokine receptor type 5 5.379e-06 0.28
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 5.722e-06 0.30
SSR5_MOUSE Sstr5 Somatostatin receptor type 5 5.849e-06 0.28
DRD1_RAT Drd1 D(1A) dopamine receptor 6.923e-06 0.35
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 7.482e-06 0.36
CCR5_MOUSE Ccr5 C-C chemokine receptor type 5 8.063e-06 0.31
ACE_RAT Ace Angiotensin-converting enzyme 9.428e-06 0.32
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 9.444e-06 0.30

Vardenafil

PDE5A_HUMAN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 2.36e-108 0.72
AMYP_PIG AMY2 Pancreatic alpha-amylase 1.725e-105 0.39
PDE6A_CANLF PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 1.195e-67 0.32
PDE6C_BOVIN PDE6C Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' 2.342e-63 0.51
PDE6C_HUMAN PDE6C Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' 1.778e-59 0.51
MRP5_HUMAN ABCC5 Multidrug resistance-associated protein 5 6.186e-56 0.38
PDE5A_RAT Pde5a cGMP-specific 3',5'-cyclic phosphodiesterase 1.819e-40 0.51
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 4.464e-26 0.51
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 4.962e-24 0.31
PDE1A_HUMAN PDE1A Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 1.665e-15 0.51
R1AB_SARS rep Replicase polyprotein 1ab 6.439e-15 0.33
E1BN64_BOVIN PDE3B Phosphodiesterase 1.199e-14 0.51
HDAC6_HUMAN HDAC6 Histone deacetylase 6 2.258e-13 0.48
PDE11_HUMAN PDE11A Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 2.079e-10 0.72
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 3.198e-09 0.36
MCLN3_HUMAN MCOLN3 Mucolipin-3 4.651e-09 0.34
CASP7_HUMAN CASP7 Caspase-7 5.362e-09 0.33
PDE6A_BOVIN PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 9.262e-09 0.51
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 2.225e-08 0.35
CASP3_HUMAN CASP3 Caspase-3 2.342e-08 0.33
AA2AR_RAT Adora2a Adenosine receptor A2a 2.63e-07 0.35
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 4.785e-07 0.30
CAH12_HUMAN CA12 Carbonic anhydrase 12 5.04e-07 0.46
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 2.011e-06 0.36
CAH9_HUMAN CA9 Carbonic anhydrase 9 5.03e-06 0.46

Rimexolone

ATTY_RAT Tat Tyrosine aminotransferase 9.753e-99 0.37
GCR_RAT Nr3c1 Glucocorticoid receptor 2.013e-57 0.60
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 7.156e-54 0.60
Q690N0_BOVIN PGR Progesterone receptor 5.534e-46 0.56
GCR_HUMAN NR3C1 Glucocorticoid receptor 1.209e-38 0.71
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.782e-33 0.60
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.877e-21 0.34
SHBG_HUMAN SHBG Sex hormone-binding globulin 2.534e-18 0.39
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.679e-18 0.60
GLNA_HUMAN GLUL Glutamine synthetase 2.679e-18 0.60
CP19A_HUMAN CYP19A1 Aromatase 9.341e-18 0.42
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 3.775e-15 0.34
IL6_HUMAN IL6 Interleukin-6 1.565e-14 0.60
NOS2_RAT Nos2 Nitric oxide synthase, inducible 3.253e-14 0.31
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 1.266e-10 0.34
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.158e-08 0.34
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.269e-07 0.34

Ceforanide

S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 1.219e-98 0.62
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 8.944e-61 0.62
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 6.73e-54 0.62
B2ZTR6_ACIBA Beta-lactamase 6.687e-43 0.38
D6NSM8_ACIBA ampC Beta-lactamase 6.687e-43 0.38
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 7.026e-31 0.38
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.948e-23 0.44
CMA1_HUMAN CMA1 Chymase 2.237e-19 0.39
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 3.119e-19 0.37
A2RP81_CITFR blaPER-2 Beta-lactamase 1.01e-14 0.32
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 1.786e-12 0.43
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 2.928e-09 0.42
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1.881e-08 0.33
STRP_STRP1 ska Streptokinase A 2.252e-08 0.58
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 3.391e-07 0.55

Tipranavir

FACE1_MOUSE Zmpste24 CAAX prenyl protease 1 homolog 1.986e-89 0.72
UBC12_HUMAN UBE2M NEDD8-conjugating enzyme Ubc12 8.796e-36 0.28
Q72874_9HIV1 pol Pol polyprotein 3.643e-20 0.72
PGAM1_HUMAN PGAM1 Phosphoglycerate mutase 1 1.265e-18 0.30
KPCA_MOUSE Prkca Protein kinase C alpha type 2.716e-18 0.32
ADRB3_MACMU ADRB3 Beta-3 adrenergic receptor 3.816e-11 0.30
PEPA5_HUMAN PGA5 Pepsin A-5 5.73e-11 0.72
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 2.557e-09 0.32
CATE_HUMAN CTSE Cathepsin E 1.233e-06 0.72

Mezlocillin

Q82134_9DELA prt Protease 5.347e-88 0.30
Q82323_9DELA Protease 9.374e-49 0.29
PRO_HTL1A gag-pro Gag-Pro polyprotein 2.812e-35 0.29
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 1.311e-32 0.40
A2RP81_CITFR blaPER-2 Beta-lactamase 5.517e-31 0.70
BLAB_BACCE Metallo-beta-lactamase type 2 8.493e-31 0.35
Q3S5C3_SALNE sugE Efflux transporter 3.351e-25 0.40
Q48435_KLEPN bla LAT-2 Beta-lactamase 3.351e-25 0.40
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 7.741e-25 0.34
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 2.847e-23 0.29
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 1.015e-18 0.33
BIRC2_HUMAN BIRC2 Baculoviral IAP repeat-containing protein 2 1.144e-14 0.32
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.561e-13 0.33
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 9.824e-12 0.33
BIRC8_HUMAN BIRC8 Baculoviral IAP repeat-containing protein 8 1.107e-11 0.28
CATL1_RAT Ctsl Cathepsin L1 1.41e-10 0.33
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 7.48e-09 0.29
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 1.271e-08 0.29
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.322e-08 0.29
AMPC_ECOLI ampC Beta-lactamase 1.008e-06 0.37

Diethylpropion

GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 3.943e-87 0.36
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.023e-70 0.42
EST1_RABIT Liver carboxylesterase 1 4.366e-65 0.40
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 3.203e-56 0.35
CBPA1_HUMAN CPA1 Carboxypeptidase A1 2.776e-55 0.35
AMYP_RAT Amy2 Pancreatic alpha-amylase 4.503e-54 0.34
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 9.204e-49 0.37
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 3.031e-47 0.37
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 2.684e-46 0.37
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 4.746e-44 0.35
ACHA_HUMAN CHRNA1 Acetylcholine receptor subunit alpha 1.806e-40 0.37
NEP_MOUSE Mme Neprilysin 1.447e-38 0.30
ACER2_HUMAN ACER2 Alkaline ceramidase 2 1.225e-37 0.30
CBX5_HUMAN CBX5 Chromobox protein homolog 5 3.56e-37 0.29
EST2_HUMAN CES2 Cocaine esterase 2.366e-36 0.42
GLT_PYRHO Glutamate transporter homolog 3.875e-36 0.29
CANX_CHICK Calpain-1 catalytic subunit 8.333e-36 0.28
SYL_STAA8 leuS Leucine--tRNA ligase 9.362e-36 0.28
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 8.661e-35 0.28
K4JQ36_LAOST ace2 Carboxylic ester hydrolase 1.807e-32 0.35
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 4.068e-32 0.40
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 2.613e-31 0.40
USP_DROME usp Protein ultraspiracle 1.835e-30 0.33
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 2.586e-28 0.35
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.172e-26 0.31
BLAB_BACCE Metallo-beta-lactamase type 2 3.612e-26 0.29
ACE_MOUSE Ace Angiotensin-converting enzyme 3.846e-26 0.30
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 3.852e-25 0.33
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 4.45e-25 0.45
ECR_DROME EcR Ecdysone receptor 5.64e-25 0.33
EST1_HUMAN CES1 Liver carboxylesterase 1 1.786e-24 0.42
Q43014_PRUAV Beta-glucosidase 1.605e-23 0.29
Q3HTL5_PLAFA fp2B Falcipain 2B 4.633e-23 0.28
SYL_ECOLI leuS Leucine--tRNA ligase 4.989e-23 0.28
Q7YWJ9_MUSDO Ache Carboxylic ester hydrolase 9.532e-23 0.35
Q9NJH6_NEPCI AO-AChE Ace-orthologous acetylcholinesterase 9.532e-23 0.35
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 1.006e-22 0.35
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 6.074e-22 0.33
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 1.369e-21 0.36
ECR_BOMMO EcR Ecdysone receptor 1.685e-21 0.39
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 1.845e-21 0.30
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 2.098e-20 0.34
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 4.667e-20 0.32
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 5.271e-20 0.30
E1BI31_BOVIN DPP9 Dipeptidyl peptidase 9 5.429e-20 0.32
NEP_HUMAN MME Neprilysin 1.448e-19 0.35
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 1.126e-18 0.30
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 2.42e-18 0.30
CATG_HUMAN CTSG Cathepsin G 2.964e-18 0.40
TBA_TRYCR Tubulin alpha chain 3.143e-18 0.29
IL8_HUMAN CXCL8 Interleukin-8 4.572e-18 0.35
PA_I000X PA Polymerase acidic protein 6.307e-18 0.34
NEP_RABIT MME Neprilysin 2.592e-17 0.34
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 3.231e-17 0.30
ACE_HUMAN ACE Angiotensin-converting enzyme 1.11e-16 0.35
COLA_CLOPE colA Collagenase ColA 1.11e-16 0.31
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.11e-16 0.30
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.11e-16 0.35
GLI1_HUMAN GLI1 Zinc finger protein GLI1 2.22e-16 0.30
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 3.331e-16 0.44
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.443e-15 0.30
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 1.554e-15 0.33
THER_BACTH npr Thermolysin 2.442e-15 0.29
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 2.998e-15 0.32
E3UJZ5_SPOLI Ecdysone receptor 4.33e-15 0.33
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 4.441e-15 0.29
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 6.55e-15 0.30
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 6.772e-15 0.41
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 1.166e-14 0.29
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.255e-14 0.35
PA_I34A1 PA Polymerase acidic protein 1.421e-14 0.34
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 4.43e-14 0.31
AOC3_HUMAN AOC3 Membrane primary amine oxidase 5.984e-14 0.33
ACHA3_HUMAN CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 6.262e-14 0.41
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 1.306e-13 0.33
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 1.492e-13 0.30
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 1.837e-13 0.66
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2.738e-13 0.32
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 3.781e-13 0.34
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 4.383e-13 0.33
MMP12_MOUSE Mmp12 Macrophage metalloelastase 6.578e-13 0.30
PDS_SYNE7 pds 15-cis-phytoene desaturase 1.094e-12 0.33
ERG2_YEAST ERG2 C-8 sterol isomerase 3.488e-12 0.32
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 6.317e-12 0.32
CBPA1_BOVIN CPA1 Carboxypeptidase A1 1.917e-11 0.35
BLA2_BACCE blm Metallo-beta-lactamase type 2 2.225e-11 0.30
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 2.237e-11 0.29
CATH_HUMAN CTSH Pro-cathepsin H 3.284e-11 0.32
Q6DMN0_TOXGO CPL Cathepsin L 3.962e-11 0.33
NK1R_RAT Tacr1 Substance-P receptor 4.747e-11 0.29
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 4.757e-11 0.30
A5H660_SCHMA HDAC8 Histone deacetylase 8 8.073e-11 0.31
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.517e-10 0.31
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.614e-10 0.36
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 1.949e-10 0.29
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 2.212e-10 0.66
CPNS1_PIG CAPNS1 Calpain small subunit 1 2.578e-10 0.29
ILVB_ARATH ALS Acetolactate synthase, chloroplastic 3.299e-10 0.29
CATB_BOVIN CTSB Cathepsin B 3.421e-10 0.28
ACE_RAT Ace Angiotensin-converting enzyme 3.442e-10 0.32
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 3.705e-10 0.30
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 5.186e-10 0.36
PAPA1_CARPA Papain 5.899e-10 0.32
CBX8_HUMAN CBX8 Chromobox protein homolog 8 6.748e-10 0.29
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 7.006e-10 0.37
NEP_PIG MME Neprilysin 7.541e-10 0.29
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 1.087e-09 0.28
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 1.482e-09 0.37
Q8WMX0_BOVIN Muscarinic receptor M1 1.579e-09 0.34
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 1.676e-09 0.41
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 1.76e-09 0.30
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 2.109e-09 0.29
Q8WSF8_APLCA Soluble acetylcholine receptor 2.659e-09 0.32
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 2.832e-09 0.30
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 3.311e-09 0.32
ITPR3_BOVIN ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 3.598e-09 0.29
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.915e-09 0.38
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 4.438e-09 0.28
P2RX4_RAT P2rx4 P2X purinoceptor 4 4.635e-09 0.30
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 5.176e-09 0.39
SCYD_MAGO7 SDH1 Scytalone dehydratase 6.639e-09 0.31
ACES_ANOGA Ace Acetylcholinesterase 7.822e-09 0.32
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 9.475e-09 0.35
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 1.088e-08 0.35
CATK_HUMAN CTSK Cathepsin K 1.168e-08 0.33
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.236e-08 0.38
SYLC_HUMAN LARS1 Leucine--tRNA ligase, cytoplasmic 1.607e-08 0.28
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 1.781e-08 0.32
LIPS_RAT Lipe Hormone-sensitive lipase 2.08e-08 0.36
UPAR_HUMAN PLAUR Urokinase plasminogen activator surface receptor 2.824e-08 0.34
CATB_HUMAN CTSB Cathepsin B 3.329e-08 0.33
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 3.557e-08 0.38
DXR_ECOLI dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3.811e-08 0.30
FEN1_HUMAN FEN1 Flap endonuclease 1 4.705e-08 0.30
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 5.093e-08 0.38
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 5.266e-08 0.41
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 5.899e-08 0.35
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 5.975e-08 0.30
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 6.126e-08 0.31
PPAP_HUMAN ACP3 Prostatic acid phosphatase 8.63e-08 0.29
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 1.067e-07 0.35
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.07e-07 0.42
CMA1_HUMAN CMA1 Chymase 1.141e-07 0.40
SC6A5_RAT Slc6a5 Sodium- and chloride-dependent glycine transporter 2 1.296e-07 0.28
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.395e-07 0.35
MAP11_HUMAN METAP1 Methionine aminopeptidase 1 1.509e-07 0.34
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 1.554e-07 0.44
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 1.572e-07 0.35
CTRB_BOVIN Chymotrypsinogen B 1.849e-07 0.29
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 2.136e-07 0.29
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.16e-07 0.38
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 2.192e-07 0.32
GPR88_HUMAN GPR88 Probable G-protein coupled receptor 88 2.471e-07 0.35
OPRD_HUMAN OPRD1 Delta-type opioid receptor 3.42e-07 0.40
POLG_HCV77 Genome polyprotein 3.716e-07 0.33
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 4.368e-07 0.29
ACE_RABIT ACE Angiotensin-converting enzyme 4.68e-07 0.39
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 4.905e-07 0.29
CHLE_HUMAN BCHE Cholinesterase 5.173e-07 0.47
AGP1_YEAST AGP1 General amino acid permease AGP1 5.192e-07 0.35
NR1H4_MOUSE Nr1h4 Bile acid receptor 5.944e-07 0.33
PRIO_MESAU PRNP Major prion protein 5.973e-07 0.32
ALBU_BOVIN ALB Serum albumin 6.072e-07 0.31
NOX1_HUMAN NOX1 NADPH oxidase 1 6.512e-07 0.35
UR2R_HUMAN UTS2R Urotensin-2 receptor 6.533e-07 0.33
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 7.196e-07 0.35
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 7.97e-07 0.31
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 8.52e-07 0.36
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 8.676e-07 0.30
AMPN_HUMAN ANPEP Aminopeptidase N 1.035e-06 0.30
PGH2_BOVIN PTGS2 Prostaglandin G/H synthase 2 1.069e-06 0.31
GRIK3_HUMAN GRIK3 Glutamate receptor ionotropic, kainate 3 1.14e-06 0.29
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.191e-06 0.36
DXR_MYCTU dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.224e-06 0.30
TSPO_RAT Tspo Translocator protein 1.224e-06 0.33
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.241e-06 0.30
TSPO_HUMAN TSPO Translocator protein 1.278e-06 0.31
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.567e-06 0.34
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.575e-06 0.36
CBX7_HUMAN CBX7 Chromobox protein homolog 7 1.766e-06 0.29
TLR4_MOUSE Tlr4 Toll-like receptor 4 1.881e-06 0.29
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.926e-06 0.29
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 2.026e-06 0.36
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 2.044e-06 0.32
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 2.07e-06 0.28
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 2.07e-06 0.28
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 2.07e-06 0.28
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 2.07e-06 0.28
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 2.07e-06 0.28
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 2.07e-06 0.28
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 2.07e-06 0.28
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 2.07e-06 0.28
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 2.07e-06 0.28
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 2.07e-06 0.28
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 2.07e-06 0.28
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 2.07e-06 0.28
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 2.07e-06 0.28
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 2.07e-06 0.28
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 2.07e-06 0.28
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 2.07e-06 0.28
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 2.07e-06 0.28
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 2.07e-06 0.28
CYSK_MYCTU cysK1 O-acetylserine sulfhydrylase 2.124e-06 0.28
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 2.26e-06 0.29
ELNE_HUMAN ELANE Neutrophil elastase 2.321e-06 0.38
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 2.849e-06 0.29
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 3.066e-06 0.40
CATK_RABIT CTSK Cathepsin K 3.614e-06 0.32
ACHP_LYMST Acetylcholine-binding protein 3.626e-06 0.32
LUCI_PHOPY Luciferin 4-monooxygenase 4.035e-06 0.33
CBPB1_HUMAN CPB1 Carboxypeptidase B 4.121e-06 0.28
AMPN_PIG ANPEP Aminopeptidase N 4.212e-06 0.31
CTRA_BOVIN Chymotrypsinogen A 4.565e-06 0.36
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 6.019e-06 0.50
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 6.094e-06 0.31
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 6.177e-06 0.32
CAH14_HUMAN CA14 Carbonic anhydrase 14 7.098e-06 0.35
ACES_HUMAN ACHE Acetylcholinesterase 7.897e-06 0.47
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 8.05e-06 0.32
SENP7_HUMAN SENP7 Sentrin-specific protease 7 8.3e-06 0.32
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 8.306e-06 0.31
CP26A_HUMAN CYP26A1 Cytochrome P450 26A1 9.367e-06 0.30
MGLL_HUMAN MGLL Monoglyceride lipase 9.626e-06 0.35

Salicylic_acid

HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 2.581e-86 0.50
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 8.702e-86 0.48
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 2.629e-84 0.42
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 1.039e-68 0.33
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 6.107e-67 0.39
Q2PCB5_DICLA ca Carbonic anhydrase 4.065e-62 0.38
MGRA_STAAU mgrA HTH-type transcriptional regulator MgrA 2.724e-60 0.48
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 6.005e-56 0.42
RAGE_RAT Ager Advanced glycosylation end product-specific receptor 1.011e-55 0.44
EST1_RABIT Liver carboxylesterase 1 2.976e-54 0.43
TCMO_HELTU CYP73A1 Trans-cinnamate 4-monooxygenase 6.114e-52 0.41
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.692e-49 0.35
PHHY_PSEFL pobA p-hydroxybenzoate hydroxylase 4.627e-48 0.38
ERF3_YEAST SUP35 Eukaryotic peptide chain release factor GTP-binding subunit 4.275e-43 0.34
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 1.722e-42 0.48
EST2_HUMAN CES2 Cocaine esterase 1.249e-41 0.43
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 3.57e-40 0.36
3HAO_HUMAN HAAO 3-hydroxyanthranilate 3,4-dioxygenase 2.83e-38 0.30
3HAO_RAT Haao 3-hydroxyanthranilate 3,4-dioxygenase 2.83e-38 0.30
Q8S3J0_BROTE ALS Acetolactate synthase 3.458e-38 0.30
POL_RSVP gag-pol Gag-Pol polyprotein 1.551e-37 0.32
STXA_SHIDY stxA Shiga toxin subunit A 1.695e-37 0.39
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 2.468e-36 0.48
C5ISA2_SHEEP TUBA4A Tubulin alpha chain 1.097e-35 0.28
MANR_PSEPU mdlA Mandelate racemase 3.139e-35 0.29
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 1.081e-34 0.28
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 3.09e-34 0.39
HMGB1_HUMAN HMGB1 High mobility group protein B1 9.4e-34 0.42
HPPD_PIG HPD 4-hydroxyphenylpyruvate dioxygenase 3.181e-33 0.29
MYOC_HUMAN MYOC Myocilin 9.257e-32 0.39
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 5.641e-31 0.41
BLAB_BACCE Metallo-beta-lactamase type 2 1.184e-30 0.35
Q44079_AERHY cphA2 Beta-lactamase 6.531e-30 0.37
BLAB_SERMA Metallo-beta-lactamase type 2 4.249e-29 0.36
DOPO_HUMAN DBH Dopamine beta-hydroxylase 1.021e-28 0.45
BXE_CLOBO botE Botulinum neurotoxin type E 2.301e-27 0.35
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 2.614e-27 0.32
AOX_TRYBB AOX Alternative oxidase, mitochondrial 5.428e-27 0.54
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 6.922e-27 0.33
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 7.022e-27 0.54
EST1_HUMAN CES1 Liver carboxylesterase 1 1.806e-25 0.43
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 2.159e-25 0.37
FABH_STAAM fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 4.904e-24 0.30
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 8.852e-24 0.41
AL1A1_RAT Aldh1a1 Retinal dehydrogenase 1 9.719e-24 0.29
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 4.99e-23 0.42
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 5.237e-23 0.33
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 6.58e-23 0.41
T1QYY3_9HIV1 int Integrase 9.845e-23 0.34
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 1.651e-22 0.37
EPHB_MYCTO Epoxide hydrolase B 1.654e-22 0.36
AAKB2_HUMAN PRKAB2 5'-AMP-activated protein kinase subunit beta-2 1.974e-21 0.34
TTHY_HUMAN TTR Transthyretin 3.572e-21 0.41
CO9_HUMAN C9 Complement component C9 6.654e-21 0.33
POLI_HUMAN POLI DNA polymerase iota 6.654e-21 0.33
Q01HZ7_ORYSA OSIGBa0132E09-OSIGBa0108L24.11 Glutamine synthetase 2.318e-20 0.32
CAH3_HUMAN CA3 Carbonic anhydrase 3 8.557e-20 0.38
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.041e-19 0.31
PTN9_HUMAN PTPN9 Tyrosine-protein phosphatase non-receptor type 9 5.177e-19 0.29
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 6.133e-19 0.48
PADI1_HUMAN PADI1 Protein-arginine deiminase type-1 6.607e-19 0.29
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.913e-18 0.33
KAT8_HUMAN KAT8 Histone acetyltransferase KAT8 4.879e-18 0.29
Q5VLE3_EMEND rmtA RmtA 4.879e-18 0.29
BLA2_BACCE blm Metallo-beta-lactamase type 2 5.934e-18 0.35
FABPI_HUMAN FABP2 Fatty acid-binding protein, intestinal 6.876e-18 0.34
O49150_SOLTU Lipoxygenase 8.47e-18 0.33
P2RX1_MOUSE P2rx1 P2X purinoceptor 1 8.934e-18 0.29
OXDD_HUMAN DDO D-aspartate oxidase 9.056e-18 0.28
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 1.882e-17 0.33
POLH_HUMAN POLH DNA polymerase eta 1.882e-17 0.33
FUT7_HUMAN FUT7 Alpha-(1,3)-fucosyltransferase 7 2.22e-16 0.36
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 2.22e-16 0.41
O77078_PLAFA fabH Beta-ketoacyl-acyl carrier protein synthase III 2.22e-16 0.29
PA_I000X PA Polymerase acidic protein 2.22e-16 0.31
Q9AQH7_STAAU dnaC Replicative DNA helicase 2.22e-16 0.41
CAH14_HUMAN CA14 Carbonic anhydrase 14 4.441e-16 0.50
G3PG_TRYCR Glyceraldehyde-3-phosphate dehydrogenase, glycosomal 4.441e-16 0.31
Q7ZJM1_9HIV1 pol Integrase 6.661e-16 0.45
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 7.772e-16 0.41
FABH_STRP3 fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.443e-15 0.30
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 1.554e-15 0.46
DNLI1_HUMAN LIG1 DNA ligase 1 3.775e-15 0.38
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 5.107e-15 0.40
KYNU_HUMAN KYNU Kynureninase 9.215e-15 0.32
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 9.437e-15 0.38
CAH6_HUMAN CA6 Carbonic anhydrase 6 1.121e-14 0.38
Q9NBA7_PLAFA Cysteine protease falcipain-3 1.998e-14 0.39
TP53B_HUMAN TP53BP1 TP53-binding protein 1 2.298e-14 0.31
CAH7_HUMAN CA7 Carbonic anhydrase 7 2.742e-14 0.50
GBB1_HUMAN GNB1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 4.385e-14 0.35
GBG2_HUMAN GNG2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 4.385e-14 0.35
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 5.94e-14 0.44
LAT1_RAT Slc7a5 Large neutral amino acids transporter small subunit 1 7.039e-14 0.30
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 1.245e-13 0.42
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.285e-13 0.38
CAH15_MOUSE Ca15 Carbonic anhydrase 15 2.259e-13 0.38
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 2.59e-13 0.42
POLG_CXB3N Genome polyprotein 3.577e-13 0.31
KTHY_HUMAN DTYMK Thymidylate kinase 3.922e-13 0.29
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 3.922e-13 0.29
Q9BEG3_BOVIN 5-lipoxygenase 4.142e-13 0.35
PTPRG_HUMAN PTPRG Receptor-type tyrosine-protein phosphatase gamma 5.185e-13 0.34
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 9.271e-13 0.29
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 1.103e-12 0.41
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.012e-12 0.54
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 9.838e-12 0.29
CAH9_HUMAN CA9 Carbonic anhydrase 9 1.066e-11 0.54
OXDA_PIG DAO D-amino-acid oxidase 1.555e-11 0.33
PTN22_HUMAN PTPN22 Tyrosine-protein phosphatase non-receptor type 22 1.691e-11 0.33
PA_I34A1 PA Polymerase acidic protein 2.477e-11 0.34
J7HAW4_RAPRA Acetolactate synthase 2.943e-11 0.30
CAH13_MOUSE Ca13 Carbonic anhydrase 13 3.57e-11 0.38
SYPC_CANAX PRS Proline--tRNA ligase, cytoplasmic 5.068e-11 0.32
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 5.451e-11 0.41
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 6.343e-11 0.29
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 6.745e-11 0.37
POLG_DEN2P Genome polyprotein 7.225e-11 0.48
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 7.966e-11 0.34
CBS_HUMAN CBS Cystathionine beta-synthase 8.191e-11 0.29
H9B8T9_CAPHI CTSB Cathepsin B 1.449e-10 0.34
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.698e-10 0.54
CAH3_BOVIN CA3 Carbonic anhydrase 3 4.337e-10 0.44
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 4.875e-10 0.37
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 5.011e-10 0.40
PADI2_HUMAN PADI2 Protein-arginine deiminase type-2 5.982e-10 0.29
PADI3_HUMAN PADI3 Protein-arginine deiminase type-3 5.982e-10 0.29
USP_DROME usp Protein ultraspiracle 6.028e-10 0.28
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 6.641e-10 0.45
BLAB_AERHY cphA Metallo-beta-lactamase type 2 6.811e-10 0.31
TLR4_MOUSE Tlr4 Toll-like receptor 4 7.105e-10 0.33
APEX1_HUMAN APEX1 DNA-(apurinic or apyrimidinic site) lyase 9.269e-10 0.35
RNH1_HUMAN RNASEH1 Ribonuclease H1 9.852e-10 0.28
PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 1.876e-09 0.33
CBPA1_BOVIN CPA1 Carboxypeptidase A1 1.919e-09 0.45
CAN_CANAL NCE103 Carbonic anhydrase 1.964e-09 0.32
1433G_HUMAN YWHAG 14-3-3 protein gamma 2.37e-09 0.33
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 2.414e-09 0.39
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 2.448e-09 0.35
PERM_HUMAN MPO Myeloperoxidase 2.809e-09 0.54
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 4.279e-09 0.32
GRIK5_RAT Grik5 Glutamate receptor ionotropic, kainate 5 4.438e-09 0.28
Q49PX0_9POXV N1L N1L 4.799e-09 0.32
HCAR2_RAT Hcar2 Hydroxycarboxylic acid receptor 2 5.207e-09 0.31
CAH2_HUMAN CA2 Carbonic anhydrase 2 7.313e-09 0.54
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 7.454e-09 0.31
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 7.454e-09 0.31
I23O1_MOUSE Ido1 Indoleamine 2,3-dioxygenase 1 1.004e-08 0.36
CAH4_HUMAN CA4 Carbonic anhydrase 4 1.808e-08 0.38
IBP3_HUMAN IGFBP3 Insulin-like growth factor-binding protein 3 1.928e-08 0.35
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 2.422e-08 0.29
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 2.718e-08 0.31
ECR_DROME EcR Ecdysone receptor 3.186e-08 0.28
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 3.96e-08 0.48
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 4.552e-08 0.46
DUS3_HUMAN DUSP3 Dual specificity protein phosphatase 3 4.79e-08 0.33
INSR_MOUSE Insr Insulin receptor 5.975e-08 0.30
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 7.156e-08 0.40
BLA1_STEMA Metallo-beta-lactamase L1 type 3 8.173e-08 0.36
TPOR_HUMAN MPL Thrombopoietin receptor 1.006e-07 0.36
REV_HV1H2 rev Protein Rev 1.106e-07 0.30
TCMO_POPKI CYP73A16 Trans-cinnamate 4-monooxygenase 1.736e-07 0.41
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 1.849e-07 0.29
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 2.996e-07 0.30
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 2.996e-07 0.30
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 3.753e-07 0.30
EGFR_MOUSE Egfr Epidermal growth factor receptor 4.177e-07 0.29
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 4.386e-07 0.50
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 4.852e-07 0.35
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 4.947e-07 0.46
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 5.365e-07 0.30
CBPA1_HUMAN CPA1 Carboxypeptidase A1 5.45e-07 0.28
NOX4_HUMAN NOX4 NADPH oxidase 4 6.323e-07 0.45
Q6FTL6_CANGA NCE103 Carbonic anhydrase 6.405e-07 0.31
FACE2_HUMAN RCE1 CAAX prenyl protease 2 7.376e-07 0.43
SENP7_HUMAN SENP7 Sentrin-specific protease 7 7.436e-07 0.36
OXDA_HUMAN DAO D-amino-acid oxidase 7.73e-07 0.33
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 8.065e-07 0.38
PRIO_HUMAN PRNP Major prion protein 8.367e-07 0.41
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 1.122e-06 0.28
NR4A1_HUMAN NR4A1 Nuclear receptor subfamily 4 group A member 1 1.365e-06 0.45
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 1.494e-06 0.34
NCOA1_HUMAN NCOA1 Nuclear receptor coactivator 1 1.568e-06 0.34
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 1.689e-06 0.38
Q76353_9HIV1 Integrase 1.774e-06 0.46
GRIK3_HUMAN GRIK3 Glutamate receptor ionotropic, kainate 3 1.944e-06 0.28
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 2.169e-06 0.33
O40947_HHV8 ORF 73 2.177e-06 0.40
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 2.185e-06 0.29
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 2.244e-06 0.34
GRM6_RAT Grm6 Metabotropic glutamate receptor 6 2.343e-06 0.31
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 2.878e-06 0.31
Q8IL32_PLAF7 Heat shock protein 90, putative 2.982e-06 0.39
DUS22_HUMAN DUSP22 Dual specificity protein phosphatase 22 3.559e-06 0.29
COMT_RAT Comt Catechol O-methyltransferase 3.743e-06 0.31
Q8IEK1_PLAF7 M1-family alanyl aminopeptidase 5.51e-06 0.29
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 6.491e-06 0.38
CAH2_BOVIN CA2 Carbonic anhydrase 2 6.674e-06 0.32
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 6.721e-06 0.41
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 8.039e-06 0.33
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 8.279e-06 0.28
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 8.558e-06 0.28
PPO2_AGABI PPO2 Polyphenol oxidase 2 9.499e-06 0.45
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 9.625e-06 0.45

Sulfapyridine

BRD4_MOUSE Brd4 Bromodomain-containing protein 4 8.422e-81 0.52
BPTF_HUMAN BPTF Nucleosome-remodeling factor subunit BPTF 1.552e-77 0.52
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 8.667e-77 0.44
QCR7_HUMAN UQCRB Cytochrome b-c1 complex subunit 7 4.743e-67 0.36
S40A1_HUMAN SLC40A1 Solute carrier family 40 member 1 2.825e-62 0.41
Q56D22_MACMU HSD11B1 Hydroxysteroid 11-beta dehydrogenase 1 2.703e-52 0.42
SMCA4_HUMAN SMARCA4 Transcription activator BRG1 6.188e-51 0.54
CCR9_HUMAN CCR9 C-C chemokine receptor type 9 2.774e-50 0.39
CYNT_HELPY cynT Carbonic anhydrase 3.931e-38 0.43
Q81VW8_BACAN folP Dihydropteroate synthase 5.548e-38 0.47
DAPAT_ARATH DAP LL-diaminopimelate aminotransferase, chloroplastic 6.694e-38 0.30
Q5TU56_ANOGA 1272966 Carbonic anhydrase 9.385e-38 0.47
ARY2_MOUSE Nat2 Arylamine N-acetyltransferase 2 3.445e-36 0.34
ARY1_HUMAN NAT1 Arylamine N-acetyltransferase 1 1.655e-35 0.34
SC5A7_RAT Slc5a7 High affinity choline transporter 1 1.527e-33 0.42
BRD7_HUMAN BRD7 Bromodomain-containing protein 7 3.056e-31 0.54
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 4.108e-29 0.47
C0IX24_STYPI CA2 Carbonic anhydrase 1.412e-28 0.43
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 9.897e-28 0.43
B2V8E3_SULSY Carbonate dehydratase 1.737e-27 0.43
B5SU02_STYPI CA Alpha carbonic anhydrase 1.737e-27 0.43
Q31FD6_HYDCU Carbonic anhydrase, alpha family 1.737e-27 0.43
A6YCJ1_9METZ Astrosclerin-3 4.903e-26 0.43
Q5XX84_CANLF HSD11B1 11-beta-hydroxysteroid dehydrogenase type 1 6.439e-26 0.42
CAN_YEAST NCE103 Carbonic anhydrase 1.12e-24 0.43
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 3.929e-24 0.40
Q44079_AERHY cphA2 Beta-lactamase 5.518e-23 0.28
METC_ECOLI metC Cystathionine beta-lyase MetC 1.765e-22 0.35
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.741e-20 0.43
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.171e-19 0.38
BAZ2B_HUMAN BAZ2B Bromodomain adjacent to zinc finger domain protein 2B 6.521e-19 0.52
CAH4_BOVIN CA4 Carbonic anhydrase 4 2.8e-18 0.47
MMP12_MOUSE Mmp12 Macrophage metalloelastase 4.146e-18 0.29
EDNRA_HUMAN EDNRA Endothelin-1 receptor 6.543e-18 0.36
EDNRB_HUMAN EDNRB Endothelin receptor type B 1.109e-17 0.36
FFAR4_RAT Ffar4 Free fatty acid receptor 4 1.882e-17 0.33
GLRA3_HUMAN GLRA3 Glycine receptor subunit alpha-3 5.121e-17 0.30
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 1.11e-16 0.32
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 7.772e-16 0.43
Q388H8_TRYB2 Glycylpeptide N-tetradecanoyltransferase 7.772e-16 0.33
CAH15_MOUSE Ca15 Carbonic anhydrase 15 8.882e-16 0.38
Q6FTL6_CANGA NCE103 Carbonic anhydrase 8.882e-16 0.43
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 1.11e-15 0.34
CAH13_MOUSE Ca13 Carbonic anhydrase 13 1.221e-15 0.47
EDNRA_RAT Ednra Endothelin-1 receptor 2.109e-15 0.43
PGES2_HUMAN PTGES2 Prostaglandin E synthase 2 3.775e-15 0.33
CAH9_HUMAN CA9 Carbonic anhydrase 9 9.215e-15 0.47
CAH2_BOVIN CA2 Carbonic anhydrase 2 1.188e-14 0.38
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.299e-14 0.50
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 2.487e-14 0.46
CAH_METTE Carbonic anhydrase 2.576e-14 0.38
SCN3A_HUMAN SCN3A Sodium channel protein type 3 subunit alpha 6.095e-14 0.33
IKBA_HUMAN NFKBIA NF-kappa-B inhibitor alpha 6.45e-14 0.36
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 7.316e-14 0.37
CAH1_HUMAN CA1 Carbonic anhydrase 1 2.687e-13 0.50
CAN_CANAL NCE103 Carbonic anhydrase 8.002e-13 0.43
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 2.659e-12 0.38
ABCBB_RAT Abcb11 Bile salt export pump 3.144e-12 0.30
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 3.996e-12 0.36
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.947e-11 0.43
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 3.597e-11 0.29
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 3.724e-11 0.36
CAH6_HUMAN CA6 Carbonic anhydrase 6 3.745e-11 0.43
KMO_RAT Kmo Kynurenine 3-monooxygenase 3.898e-11 0.36
MBD2_HUMAN MBD2 Methyl-CpG-binding domain protein 2 4.196e-11 0.30
KAT2B_HUMAN KAT2B Histone acetyltransferase KAT2B 4.76e-11 0.52
LIMK2_HUMAN LIMK2 LIM domain kinase 2 5.287e-11 0.37
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 9.574e-11 0.36
SCN9A_HUMAN SCN9A Sodium channel protein type 9 subunit alpha 2.113e-10 0.40
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 2.173e-10 0.43
BRD4_HUMAN BRD4 Bromodomain-containing protein 4 2.29e-10 0.57
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 2.561e-10 0.43
EDNRA_PIG EDNRA Endothelin-1 receptor 2.799e-10 0.33
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 9.062e-10 0.50
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.403e-09 0.47
KCNN1_HUMAN KCNN1 Small conductance calcium-activated potassium channel protein 1 1.582e-09 0.30
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 1.61e-09 0.36
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 2.039e-09 0.29
PFKA_TRYCC pfk ATP-dependent 6-phosphofructokinase 2.495e-09 0.30
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 3.562e-09 0.36
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 3.648e-09 0.31
PFKA_TRYBB pfk ATP-dependent 6-phosphofructokinase 1.005e-08 0.30
RT109_YEAST RTT109 Histone acetyltransferase RTT109 1.86e-08 0.30
SCN9A_RAT Scn9a Sodium channel protein type 9 subunit alpha 4.022e-08 0.32
TF65_HUMAN RELA Transcription factor p65 4.635e-08 0.36
KCNN2_HUMAN KCNN2 Small conductance calcium-activated potassium channel protein 2 5.219e-08 0.30
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 7.387e-08 0.29
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 1.11e-07 0.36
5NTD_HUMAN NT5E 5'-nucleotidase 1.157e-07 0.37
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.506e-07 0.43
DHI1_HUMAN HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 2.01e-07 0.61
CBP_HUMAN CREBBP CREB-binding protein 3.094e-07 0.54
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.446e-06 0.43
BRD3_HUMAN BRD3 Bromodomain-containing protein 3 1.546e-06 0.54
NSD2_HUMAN NSD2 Histone-lysine N-methyltransferase NSD2 1.856e-06 0.31
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 3.716e-06 0.44
LUCI_AQULA Luciferin 4-monooxygenase 3.933e-06 0.30
GSK3B_RAT Gsk3b Glycogen synthase kinase-3 beta 5.619e-06 0.30
GCN5_YEAST GCN5 Histone acetyltransferase GCN5 6.347e-06 0.29
KCNN3_HUMAN KCNN3 Small conductance calcium-activated potassium channel protein 3 9.582e-06 0.30

Chlorhexidine

PAO1_MAIZE MPAO1 Polyamine oxidase 1 6.741e-80 0.51
PSBA_SPIOL psbA Photosystem II protein D1 1.122e-43 0.40
AGUA_STRMU aguA Putative agmatine deiminase 6.678e-41 0.32
AL1A2_CHICK ALDH1A2 Retinal dehydrogenase 2 1.443e-37 0.30
Q9GSW0_PLAFA dhs Deoxyhypusine synthase 1.443e-37 0.30
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.198e-36 0.38
AATC_HUMAN GOT1 Aspartate aminotransferase, cytoplasmic 1.609e-35 0.28
DHYS_RAT Dhps Deoxyhypusine synthase 9.287e-27 0.30
TYTR_TRYCR TPR Trypanothione reductase 2.047e-25 0.41
EPHB_MYCTO Epoxide hydrolase B 2.07e-23 0.38
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 1.181e-21 0.38
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.82e-19 0.39
S100B_HUMAN S100B Protein S100-B 6.412e-19 0.29
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 6.792e-19 0.38
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 2.196e-13 0.39
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 4.004e-12 0.39
PSBA_MARPO psbA Photosystem II protein D1 2.548e-11 0.36
AL1A3_HUMAN ALDH1A3 Aldehyde dehydrogenase family 1 member A3 4.393e-11 0.30
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 4.853e-11 0.39
THAS_RAT Tbxas1 Thromboxane-A synthase 5.56e-11 0.36
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 1.645e-09 0.30
HRH3_CAVPO HRH3 Histamine H3 receptor 6.692e-09 0.56
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 1.557e-08 0.47
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 2.748e-08 0.41
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 2.971e-08 0.41
Q6FTL6_CANGA NCE103 Carbonic anhydrase 1.935e-07 0.33
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 2.651e-07 0.30
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 2.746e-07 0.32
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 3.662e-07 0.32
Q25615_ONCVO Chitinase 3.706e-07 0.29
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.381e-06 0.30
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.547e-06 0.32
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.278e-06 0.39
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.521e-06 0.29
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 5.051e-06 0.41
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 5.241e-06 0.40
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 8.881e-06 0.38

Pseudoephedrine

GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 4.734e-79 0.36
ACER2_HUMAN ACER2 Alkaline ceramidase 2 7.865e-58 0.46
PPAP_HUMAN ACP3 Prostatic acid phosphatase 2.067e-46 0.36
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 1.651e-34 0.37
BLAB_BACCE Metallo-beta-lactamase type 2 1.643e-33 0.38
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 2.874e-33 0.39
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 2.026e-28 0.35
ACE_MOUSE Ace Angiotensin-converting enzyme 6.284e-27 0.31
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 2.034e-26 0.37
AOC3_HUMAN AOC3 Membrane primary amine oxidase 1.427e-23 0.48
NSMA_HUMAN SMPD2 Sphingomyelin phosphodiesterase 2 4.633e-23 0.28
MANR_PSEPU mdlA Mandelate racemase 3.381e-22 0.35
EST1_RABIT Liver carboxylesterase 1 6.989e-22 0.32
Q8VH27_CAVPO GPM2 Muscarinic acetylcholine receptor 6.586e-18 0.29
G3HDX1_CRIGR Alpha-1B adrenergic receptor 5.295e-17 0.32
MA2A1_HUMAN MAN2A1 Alpha-mannosidase 2 1.11e-16 0.32
MA1B1_HUMAN MAN1B1 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 3.331e-16 0.32
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 1.332e-15 0.39
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 7.994e-15 0.33
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 4.652e-14 0.33
CALM_BOVIN CALM Calmodulin 5.228e-13 0.35
EST2_HUMAN CES2 Cocaine esterase 6.251e-13 0.39
BIRC8_HUMAN BIRC8 Baculoviral IAP repeat-containing protein 8 1.508e-11 0.28
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 1.436e-10 0.44
PPO1_AGABI PPO1 Polyphenol oxidase 1 1.441e-10 0.33
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 3.532e-10 0.39
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 5.779e-10 0.47
MENB_MYCTU menB 1,4-dihydroxy-2-naphthoyl-CoA synthase 5.982e-10 0.29
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 7.2e-10 0.31
BLAB_AERHY cphA Metallo-beta-lactamase type 2 1.645e-09 0.30
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 2.614e-09 0.35
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 2.734e-09 0.30
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 3.598e-09 0.29
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.084e-08 0.43
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.964e-08 0.47
EST1_HUMAN CES1 Liver carboxylesterase 1 2.377e-08 0.39
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 3.189e-08 0.29
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 3.301e-08 0.29
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 4.433e-08 0.68
NK1R_RAT Tacr1 Substance-P receptor 5.388e-08 0.29
BLA2_BACCE blm Metallo-beta-lactamase type 2 1.468e-07 0.38
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 3.614e-07 0.56
Q9WTR4_RAT Slc6a2 Transporter 5.476e-07 0.47
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 5.775e-07 0.34
SCYD_MAGO7 SDH1 Scytalone dehydratase 7.535e-07 0.31
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 7.834e-07 0.29
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.071e-06 0.30
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.085e-06 0.50
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 1.864e-06 0.32
CBPA1_BOVIN CPA1 Carboxypeptidase A1 3.003e-06 0.33
SUIS_HUMAN SI Sucrase-isomaltase, intestinal 4.107e-06 0.28
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 4.553e-06 0.39
OXDA_MOUSE Dao D-amino-acid oxidase 5.379e-06 0.28

Benzphetamine

Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.591e-72 0.37
G6PC_HUMAN G6PC Glucose-6-phosphatase 1.216e-70 0.33
NEP_MOUSE Mme Neprilysin 1.184e-68 0.34
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 5.879e-67 0.48
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 5.821e-60 0.33
CBPA1_HUMAN CPA1 Carboxypeptidase A1 8.485e-51 0.37
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 8.642e-48 0.34
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.282e-40 0.34
NEP_RABIT MME Neprilysin 6.86e-38 0.39
AMPB_MOUSE Rnpep Aminopeptidase B 1.225e-37 0.30
AMPL_BOVIN LAP3 Cytosol aminopeptidase 1.225e-37 0.30
CANX_CHICK Calpain-1 catalytic subunit 3.56e-37 0.29
AMPB_RAT Rnpep Aminopeptidase B 2.889e-34 0.32
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 2.645e-33 0.42
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 7.441e-32 0.31
ACE_MOUSE Ace Angiotensin-converting enzyme 4.868e-28 0.32
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 8.264e-28 0.62
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 2.46e-25 0.31
DRD2_CHLAE DRD2 D(2) dopamine receptor 1.065e-24 0.33
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 3.331e-24 0.38
Q704V1_PSEAI blaGIM-1 GIM-1 protein 4.904e-24 0.30
Q3HTL5_PLAFA fp2B Falcipain 2B 6.243e-24 0.29
NEP_RAT Mme Neprilysin 7.717e-24 0.33
AMPB_HUMAN RNPEP Aminopeptidase B 1.449e-22 0.32
AMPL_HUMAN LAP3 Cytosol aminopeptidase 2.194e-22 0.33
PAPA1_CARPA Papain 2.953e-21 0.32
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 6.361e-21 0.67
Q39829_SOYBN Lipoxygenase 9.314e-20 0.31
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 9.052e-19 0.30
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 2.064e-18 0.40
VM1B1_BOTAS Snake venom metalloproteinase BaP1 2.139e-18 0.29
AMP1_PLAFQ M1 family aminopeptidase 3.349e-18 0.30
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 4.377e-18 0.45
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 7.088e-18 0.28
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 4.069e-17 0.39
AOC3_HUMAN AOC3 Membrane primary amine oxidase 5.023e-17 0.48
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 2.22e-16 0.33
ACE_HUMAN ACE Angiotensin-converting enzyme 2.109e-15 0.39
NEP_HUMAN MME Neprilysin 6.173e-14 0.33
NK1R_RAT Tacr1 Substance-P receptor 1.315e-13 0.36
Q72874_9HIV1 pol Pol polyprotein 1.622e-13 0.33
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 2.134e-13 0.48
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 2.701e-13 0.29
MMP12_MOUSE Mmp12 Macrophage metalloelastase 2.286e-12 0.29
AMPX_VIBPR Bacterial leucyl aminopeptidase 3.325e-12 0.30
THER_BACTH npr Thermolysin 7.596e-12 0.33
CALM_BOVIN CALM Calmodulin 8.327e-12 0.32
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 9.536e-12 0.45
CBPA1_BOVIN CPA1 Carboxypeptidase A1 1.133e-11 0.33
AMPN_MOUSE Anpep Aminopeptidase N 4.196e-11 0.30
AMPN_HUMAN ANPEP Aminopeptidase N 4.545e-11 0.34
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 5.899e-11 0.67
AMPN_PIG ANPEP Aminopeptidase N 6.484e-11 0.36
CATH_HUMAN CTSH Pro-cathepsin H 9.483e-11 0.31
RORB_HUMAN RORB Nuclear receptor ROR-beta 1.043e-10 0.31
CPNS1_PIG CAPNS1 Calpain small subunit 1 1.741e-10 0.30
SOAT1_CHLAE SOAT1 Sterol O-acyltransferase 1 1.936e-10 0.30
GALR1_RAT Galr1 Galanin receptor type 1 2.244e-10 0.30
GALR2_RAT Galr2 Galanin receptor type 2 2.244e-10 0.30
NEP_PIG MME Neprilysin 3.105e-10 0.30
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 5.732e-10 0.29
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.547e-09 0.30
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 1.819e-09 0.33
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.863e-09 0.30
NISCH_HUMAN NISCH Nischarin 2.259e-09 0.42
Q49PX0_9POXV N1L N1L 2.37e-09 0.33
NISCH_RAT Nisch Nischarin 3.422e-09 0.42
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 3.995e-09 0.45
CALM1_HUMAN CALM1 Calmodulin-1 5.818e-09 0.32
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 7.511e-09 0.33
SOAT2_CHLAE SOAT2 Sterol O-acyltransferase 2 3.632e-08 0.30
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 4.078e-08 0.38
MMP13_RAT Mmp13 Collagenase 3 7.986e-08 0.31
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 8.352e-08 0.29
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 1.083e-07 0.35
ERG2_YEAST ERG2 C-8 sterol isomerase 1.422e-07 0.29
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 1.642e-07 0.41
AOFB_RAT Maob Amine oxidase [flavin-containing] B 1.713e-07 0.62
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 1.862e-07 0.33
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 2.29e-07 0.40
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 2.651e-07 0.30
OPRM_RAT Oprm1 Mu-type opioid receptor 3.169e-07 0.39
BLA2_BACCE blm Metallo-beta-lactamase type 2 4.38e-07 0.35
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 4.905e-07 0.29
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 8.93e-07 0.36
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 9.268e-07 0.40
RORG_HUMAN RORC Nuclear receptor ROR-gamma 9.478e-07 0.33
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 1.025e-06 0.62
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 1.034e-06 0.32
ACE_RAT Ace Angiotensin-converting enzyme 1.081e-06 0.34
NK1R_CAVPO TACR1 Substance-P receptor 1.201e-06 0.31
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 1.347e-06 0.38
ALBU_BOVIN ALB Serum albumin 1.414e-06 0.29
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 1.845e-06 0.30
Q9V396_DROME CAH1 Carbonic anhydrase 1 1.896e-06 0.41
Q9VTU8_DROME CAH2 Carbonic anhydrase 2, isoform A 1.896e-06 0.41
MMP8_HUMAN MMP8 Neutrophil collagenase 2.124e-06 0.31
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.245e-06 0.40
PGH2_BOVIN PTGS2 Prostaglandin G/H synthase 2 2.409e-06 0.29
RORA_HUMAN RORA Nuclear receptor ROR-alpha 2.552e-06 0.31
EST1_PIG Liver carboxylesterase 3.199e-06 0.30
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 3.898e-06 0.35
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 4.267e-06 0.30
CAN1_RAT Capn1 Calpain-1 catalytic subunit 4.586e-06 0.30
ACES_HUMAN ACHE Acetylcholinesterase 6.999e-06 0.38
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 7.112e-06 0.29
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 8.912e-06 0.38
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 9.444e-06 0.30

Testolactone

CP19A_HUMAN CYP19A1 Aromatase 2.628e-65 0.66
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 2.415e-45 0.43
Q690N0_BOVIN PGR Progesterone receptor 3.664e-44 0.36
SHBG_HUMAN SHBG Sex hormone-binding globulin 4.037e-37 0.40
GCR_RAT Nr3c1 Glucocorticoid receptor 1.818e-32 0.43
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 2.158e-24 0.30
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.657e-23 0.43
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 2.906e-22 0.36
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 2.755e-20 0.32
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.152e-19 0.38
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 4.441e-16 0.34
ANDR_RAT Ar Androgen receptor 7.772e-16 0.36
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 6.106e-15 0.36
NOS2_RAT Nos2 Nitric oxide synthase, inducible 2.509e-14 0.31
GCR_HUMAN NR3C1 Glucocorticoid receptor 2.698e-14 0.43
PRGR_RAT Pgr Progesterone receptor 2.753e-14 0.31
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 3.286e-14 0.32
GLNA_HUMAN GLUL Glutamine synthetase 2.311e-13 0.43
PRGR_RABIT PGR Progesterone receptor 1.89e-12 0.34
GCR_MOUSE Nr3c1 Glucocorticoid receptor 2.104e-12 0.43
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 8.745e-11 0.32
IL6_HUMAN IL6 Interleukin-6 1.193e-10 0.43
ANDR_HUMAN AR Androgen receptor 1.971e-10 0.43
PRGR_HUMAN PGR Progesterone receptor 3.437e-09 0.43
ERG2_YEAST ERG2 C-8 sterol isomerase 4.62e-09 0.36
ANDR_MOUSE Ar Androgen receptor 1.913e-08 0.36
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 3.483e-08 0.32
MCR_HUMAN NR3C2 Mineralocorticoid receptor 3.62e-08 0.43
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.682e-07 0.34
PPO2_AGABI PPO2 Polyphenol oxidase 2 3.534e-07 0.57

Loteprednol_etabonate

ATTY_RAT Tat Tyrosine aminotransferase 1.974e-64 0.31
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 3.448e-63 0.57
Q690N0_BOVIN PGR Progesterone receptor 2.03e-53 0.46
GCR_RAT Nr3c1 Glucocorticoid receptor 5.125e-40 0.57
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 3.068e-38 0.34
GCR_HUMAN NR3C1 Glucocorticoid receptor 1.474e-36 0.57
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.099e-34 0.57
SHBG_HUMAN SHBG Sex hormone-binding globulin 8.596e-33 0.40
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 4.778e-28 0.34
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 5.023e-26 0.57
CP19A_HUMAN CYP19A1 Aromatase 7.556e-26 0.41
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 6.63e-22 0.34
GLNA_HUMAN GLUL Glutamine synthetase 2.259e-17 0.57
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 2.331e-15 0.35
NOS2_RAT Nos2 Nitric oxide synthase, inducible 4.03e-14 0.31
IL6_HUMAN IL6 Interleukin-6 8.382e-14 0.57
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 5.519e-13 0.34
ANDR_RAT Ar Androgen receptor 8.702e-13 0.46
ANDR_MOUSE Ar Androgen receptor 6.589e-10 0.30
PRGR_RABIT PGR Progesterone receptor 3.494e-09 0.29
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 3.901e-09 0.34
ERG2_YEAST ERG2 C-8 sterol isomerase 9.929e-08 0.29
PPO2_AGABI PPO2 Polyphenol oxidase 2 8.38e-07 0.44
MCR_HUMAN NR3C2 Mineralocorticoid receptor 4.684e-06 0.57

Guaifenesin

B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 4.749e-61 0.43
Q5YLN7_CANLF SCN5A Voltage-gated sodium channel Nav1.5 cardiac isoform 1.986e-54 0.43
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.01e-51 0.40
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.654e-41 0.48
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 3.889e-41 0.53
NAT_MYCSM nat Arylamine N-acetyltransferase 1.52e-40 0.32
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 5.552e-39 0.45
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 3.033e-37 0.42
CASR_BOVIN CASR Extracellular calcium-sensing receptor 3.875e-36 0.29
ANDR_MOUSE Ar Androgen receptor 4.544e-36 0.40
Q49PX0_9POXV N1L N1L 7.748e-33 0.32
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 7.91e-27 0.39
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 5.387e-20 0.32
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 3.683e-19 0.42
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 1.439e-18 0.44
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 4.281e-18 0.43
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 1.034e-17 0.43
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.546e-17 0.42
CASR_HUMAN CASR Extracellular calcium-sensing receptor 1.11e-16 0.50
PTPRE_HUMAN PTPRE Receptor-type tyrosine-protein phosphatase epsilon 1.11e-16 0.31
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 6.661e-16 0.36
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 2.442e-15 0.32
LOX12_MOUSE Alox12 Arachidonate 12-lipoxygenase, 12S-type 4.441e-15 0.29
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 1.51e-14 0.42
SCN9A_MOUSE Scn9a Sodium channel protein type 9 subunit alpha 1.543e-14 0.43
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 7.172e-14 0.42
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 3.771e-13 0.33
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 4.66e-13 0.42
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 4.283e-12 0.33
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 5.46e-12 0.42
ADRB2_MOUSE Adrb2 Beta-2 adrenergic receptor 9.7e-12 0.29
SCN1A_HUMAN SCN1A Sodium channel protein type 1 subunit alpha 1.261e-11 0.32
CAH3_BOVIN CA3 Carbonic anhydrase 3 7.225e-11 0.48
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.415e-10 0.28
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.77e-10 0.31
VDR_HUMAN VDR Vitamin D3 receptor 4.367e-10 0.40
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 1.021e-09 0.30
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 4.045e-09 0.31
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 6.665e-08 0.31
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 1.084e-07 0.34
PD1L1_HUMAN CD274 Programmed cell death 1 ligand 1 2.68e-07 0.28
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 4.395e-07 0.33
PIM3_RAT Pim3 Serine/threonine-protein kinase pim-3 6.183e-07 0.42
MEP50_HUMAN WDR77 Methylosome protein 50 1.04e-06 0.36
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 1.22e-06 0.36
GRIK3_HUMAN GRIK3 Glutamate receptor ionotropic, kainate 3 1.482e-06 0.29
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 1.705e-06 0.42
PRIO_SHEEP PRNP Major prion protein 1.959e-06 0.29
NR1H4_MOUSE Nr1h4 Bile acid receptor 2e-06 0.31
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 2.14e-06 0.42
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 2.317e-06 0.42
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 3.354e-06 0.29
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 3.559e-06 0.29
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 5.78e-06 0.31
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 9.583e-06 0.31

Bitolterol

ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 3.375e-60 0.49
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.544e-53 0.40
ACRO_HUMAN ACR Acrosin 5.511e-41 0.41
ECR_CHITE EcR Ecdysone receptor 6.694e-38 0.30
ECR_HELVI EcR Ecdysone receptor 6.694e-38 0.30
O45117_CHITE USP-1 Ultraspiracle 6.694e-38 0.30
Q6IVK1_PLOIN USP 6.694e-38 0.30
Q6RVD3_PLOIN Ecdysone receptor 6.694e-38 0.30
Q7SIF6_HELVI Gene regulation protein 6.694e-38 0.30
Q8I1M8_CHISP CsUSP Ultraspiracle 6.694e-38 0.30
Q8MYA6_CHISP CsEcR-B1 Ecdysone receptor B1 isoform 6.694e-38 0.30
Q962I5_LUCCU Ultraspiracle protein 6.694e-38 0.30
USP_CHOFU USP Protein ultraspiracle homolog 6.694e-38 0.30
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 3.623e-34 0.30
ENTK_HUMAN TMPRSS15 Enteropeptidase 1.437e-31 0.32
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 1.798e-31 0.39
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 9.058e-29 0.30
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 1.683e-28 0.41
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 4.718e-28 0.54
PA2A1_ECHCA Acidic phospholipase A2 EC-I 4.036e-26 0.32
PA2B1_NAJME Basic phospholipase A2 1 4.036e-26 0.32
PA2BA_PROFL Basic phospholipase A2 PLA-A 4.036e-26 0.32
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 3.938e-21 0.41
Q4W6C8_LEPDE LdUSP Ultraspiracle 6.741e-19 0.30
Q4W6D0_LEPDE LdEcR-A Ecdysone receptor A isoform 6.741e-19 0.30
TRY1_HUMAN PRSS1 Trypsin-1 5.838e-18 0.41
GLP1R_RAT Glp1r Glucagon-like peptide 1 receptor 1.475e-17 0.29
Q9GSG8_AEDAE Ultraspiracle isoform-A 8.882e-16 0.30
PTPRE_HUMAN PTPRE Receptor-type tyrosine-protein phosphatase epsilon 5.662e-15 0.28
G3HDX1_CRIGR Alpha-1B adrenergic receptor 6.106e-15 0.28
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 4.43e-14 0.31
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 7.883e-14 0.30
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 9.917e-13 0.44
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 4.959e-12 0.29
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 1.865e-11 0.36
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 4.144e-11 0.36
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 6.822e-11 0.36
Q9JKC1_RAT Bche Carboxylic ester hydrolase 7.096e-10 0.34
ECR_LUCCU EcR Ecdysone receptor 1.37e-09 0.30
ACHA_HUMAN CHRNA1 Acetylcholine receptor subunit alpha 1.474e-09 0.36
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 2.752e-08 0.33
E3UJZ5_SPOLI Ecdysone receptor 7.634e-08 0.31
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 1.502e-07 0.31
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.985e-07 0.35
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 2.193e-07 0.44
CP26B_HUMAN CYP26B1 Cytochrome P450 26B1 2.196e-07 0.30
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 2.362e-07 0.29
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 4.953e-07 0.31
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 8.619e-07 0.29
O77240_CHOFU EcR Ecdysone receptor isoform A 8.676e-07 0.30
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 9.991e-07 0.31
RARB_MOUSE Rarb Retinoic acid receptor beta 1.142e-06 0.28
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 1.384e-06 0.29
EIS_MYCTU eis N-acetyltransferase Eis 2.07e-06 0.28
HCN1_HUMAN HCN1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 2.889e-06 0.32
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 2.948e-06 0.33
ECR_BOMMO EcR Ecdysone receptor 5.459e-06 0.31
RARA_MOUSE Rara Retinoic acid receptor alpha 5.463e-06 0.28
CHLE_HORSE BCHE Cholinesterase 6.744e-06 0.45

Aminolevulinic_acid

GBRT_HUMAN GABRQ Gamma-aminobutyric acid receptor subunit theta 1.225e-59 0.48
S6A13_RAT Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.225e-59 0.48
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 5.466e-52 0.55
CP4F2_HUMAN CYP4F2 Cytochrome P450 4F2 3.875e-36 0.29
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 2.881e-26 0.55
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 4.997e-26 0.48
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 1.42e-24 0.48
GABT_PIG ABAT 4-aminobutyrate aminotransferase, mitochondrial 2.162e-24 0.39
KDM7A_HUMAN KDM7A Lysine-specific demethylase 7A 6.654e-21 0.33
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 5.177e-20 0.33
BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 1.143e-19 0.34
GNPAT_HUMAN GNPAT Dihydroxyacetone phosphate acyltransferase 4.879e-18 0.29
ACEA_CANAX ICL1 Isocitrate lyase 1.11e-16 0.32
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 5.551e-16 0.30
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 3.875e-14 0.42
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 1.357e-13 0.43
Q6RY99_RAT Tetraspanin 2.23e-13 0.36
CGL_HUMAN CTH Cystathionine gamma-lyase 1.88e-12 0.30
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 2.201e-11 0.55
CBS_HUMAN CBS Cystathionine beta-synthase 2.506e-11 0.30
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 2.649e-11 0.42
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 3.185e-11 0.48
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 1.286e-09 0.48
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 2.643e-09 0.48
GBRR1_HUMAN GABRR1 Gamma-aminobutyric acid receptor subunit rho-1 2.79e-08 0.48
BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 2.994e-07 0.28
GABR2_RAT Gabbr2 Gamma-aminobutyric acid type B receptor subunit 2 3.402e-07 0.48
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 9.675e-07 0.38
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.716e-06 0.32
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 4.103e-06 0.48

Fulvestrant

Q95MF8_PIG Sulfotransferase 2.983e-59 0.33
STS_HUMAN STS Steryl-sulfatase 4.697e-56 0.37
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 4.157e-53 0.55
SHBG_HUMAN SHBG Sex hormone-binding globulin 2.857e-34 0.45
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 8.153e-33 0.45
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 8.143e-32 0.41
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 6.285e-29 0.38
ERR1_HUMAN ESRRA Steroid hormone receptor ERR1 1.052e-28 0.77
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 7.027e-28 0.45
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 9.005e-24 0.33
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 3.565e-21 0.34
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 5.378e-18 0.45
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.658e-17 0.45
ESR1_HUMAN ESR1 Estrogen receptor 1.554e-15 0.77
ESR1_MOUSE Esr1 Estrogen receptor 5.707e-14 0.45
ESR2_MOUSE Esr2 Estrogen receptor beta 5.707e-14 0.45
ESR1_RAT Esr1 Estrogen receptor 1.248e-12 0.77
ESR2_HUMAN ESR2 Estrogen receptor beta 4.816e-12 0.77
ANDR_HUMAN AR Androgen receptor 7.219e-10 0.45
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.938e-09 0.45
Q690N0_BOVIN PGR Progesterone receptor 2.862e-09 0.45
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 1.068e-06 0.32
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 1.069e-06 0.31
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.09e-06 0.45

Phenformin

NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 4.339e-57 0.37
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 5.474e-56 0.50
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 5.791e-56 0.37
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 6.243e-47 0.33
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 9.743e-42 0.42
TYTR_TRYCR TPR Trypanothione reductase 4.537e-35 0.38
KLK8_HUMAN KLK8 Kallikrein-8 9.887e-33 0.33
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 2.756e-31 0.32
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 2.616e-30 0.30
KLK4_HUMAN KLK4 Kallikrein-4 4.698e-30 0.33
ASAH1_HUMAN ASAH1 Acid ceramidase 1.56e-29 0.36
MCA2_TRYBB MCA2 Metacaspase 6.416e-29 0.32
CHIA_SERMA chiA Chitinase A 1.398e-28 0.31
Q8I6Z5_PLAF7 Plasmepsin V 1.501e-28 0.31
KLK2_HUMAN KLK2 Kallikrein-2 1.021e-24 0.33
S100B_HUMAN S100B Protein S100-B 2.197e-23 0.37
PAO1_MAIZE MPAO1 Polyamine oxidase 1 3.384e-23 0.47
AMPN_PIG ANPEP Aminopeptidase N 3.475e-21 0.44
SCNNA_HUMAN SCNN1A Amiloride-sensitive sodium channel subunit alpha 3.942e-21 0.37
AMP1_PLAFQ M1 family aminopeptidase 4.102e-21 0.40
PADI1_HUMAN PADI1 Protein-arginine deiminase type-1 4.378e-19 0.29
PADI3_HUMAN PADI3 Protein-arginine deiminase type-3 4.378e-19 0.29
LIPL_HUMAN LPL Lipoprotein lipase 1.523e-18 0.29
VM1B1_BOTAS Snake venom metalloproteinase BaP1 3.488e-18 0.29
TMPS2_HUMAN TMPRSS2 Transmembrane protease serine 2 9.056e-18 0.28
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.11e-16 0.44
FTSZ_ECOLI ftsZ Cell division protein FtsZ 1.11e-15 0.30
FTSZ_STAAU ftsZ Cell division protein FtsZ 1.11e-15 0.30
AMPN_HUMAN ANPEP Aminopeptidase N 1.332e-15 0.39
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 3.22e-15 0.30
AMPB_RAT Rnpep Aminopeptidase B 5.995e-15 0.36
CBPA1_BOVIN CPA1 Carboxypeptidase A1 9.437e-15 0.37
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.032e-14 0.47
SCYD_MAGO7 SDH1 Scytalone dehydratase 1.302e-13 0.36
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.337e-13 0.62
HRH2_CAVPO HRH2 Histamine H2 receptor 1.715e-13 0.39
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 1.884e-13 0.29
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 1.884e-13 0.29
NEP_MOUSE Mme Neprilysin 2.862e-13 0.29
5HT3B_MOUSE Htr3b 5-hydroxytryptamine receptor 3B 3.049e-13 0.33
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 3.536e-13 0.38
CAH2_HUMAN CA2 Carbonic anhydrase 2 3.7e-13 0.62
NK1R_RAT Tacr1 Substance-P receptor 6.392e-13 0.33
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 7.058e-13 0.29
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 1.076e-12 0.42
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 1.1e-12 0.42
AMPL_PIG LAP3 Cytosol aminopeptidase 1.713e-12 0.39
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 3.497e-12 0.30
HRH2_HUMAN HRH2 Histamine H2 receptor 4.502e-12 0.39
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 1.492e-11 0.33
CPNS1_PIG CAPNS1 Calpain small subunit 1 3.441e-11 0.31
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 3.561e-11 0.32
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 4.083e-11 0.36
FURIN_HUMAN FURIN Furin 5.449e-11 0.33
AMPB_HUMAN RNPEP Aminopeptidase B 6.878e-11 0.29
BGAL_BOVIN GLB1 Beta-galactosidase 7.645e-11 0.33
AOC3_HUMAN AOC3 Membrane primary amine oxidase 1.017e-10 0.48
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 1.045e-10 0.42
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 2.552e-10 0.47
CAH4_BOVIN CA4 Carbonic anhydrase 4 2.616e-10 0.40
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.415e-10 0.34
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 5.39e-10 0.42
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 6.212e-10 0.40
CHIB_SERMA chiB Chitinase B 6.606e-10 0.31
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 8.168e-10 0.41
PADI2_HUMAN PADI2 Protein-arginine deiminase type-2 9.181e-10 0.28
FUCO_HUMAN FUCA1 Tissue alpha-L-fucosidase 9.509e-10 0.33
CATL1_HUMAN CTSL Cathepsin L1 1.204e-09 0.35
CAH9_HUMAN CA9 Carbonic anhydrase 9 2.377e-09 0.62
CAH12_HUMAN CA12 Carbonic anhydrase 12 3.093e-09 0.62
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 4.635e-09 0.30
HRH3_CAVPO HRH3 Histamine H3 receptor 5.661e-09 0.49
Q6FTL6_CANGA NCE103 Carbonic anhydrase 9.058e-09 0.40
LIPE_MOUSE Lipg Endothelial lipase 1.048e-08 0.31
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 1.702e-08 0.29
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.709e-08 0.39
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 2.021e-08 0.31
CAH7_HUMAN CA7 Carbonic anhydrase 7 2.085e-08 0.42
KLF5_HUMAN KLF5 Krueppel-like factor 5 2.123e-08 0.39
CAN_CANAL NCE103 Carbonic anhydrase 2.991e-08 0.40
AMPL_HUMAN LAP3 Cytosol aminopeptidase 3.082e-08 0.32
ENV_MMTVG env Envelope glycoprotein gp70 3.301e-08 0.29
SPRE_HUMAN SPR Sepiapterin reductase 3.632e-08 0.30
MMP8_HUMAN MMP8 Neutrophil collagenase 4.016e-08 0.39
AOC3_BOVIN AOC3 Membrane primary amine oxidase 4.633e-08 0.30
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 5.39e-08 0.30
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 8.469e-08 0.42
HRH1_CAVPO HRH1 Histamine H1 receptor 9.012e-08 0.39
LEG7_HUMAN LGALS7; LGALS7B Galectin-7 1.031e-07 0.29
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 1.102e-07 0.30
EGFR_MOUSE Egfr Epidermal growth factor receptor 1.124e-07 0.31
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 1.144e-07 0.38
AOC3_RAT Aoc3 Membrane primary amine oxidase 1.515e-07 0.30
CRTM_STAAU crtM 4,4'-diapophytoene synthase 1.524e-07 0.32
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 1.839e-07 0.68
PERM_HUMAN MPO Myeloperoxidase 2.095e-07 0.41
GAG_AVIER gag Gag polyprotein 4.177e-07 0.29
TPH1_HUMAN TPH1 Tryptophan 5-hydroxylase 1 4.294e-07 0.38
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 4.907e-07 0.41
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 6.177e-07 0.30
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 9.05e-07 0.38
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 9.846e-07 0.33
CATB_BOVIN CTSB Cathepsin B 1.004e-06 0.31
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 1.38e-06 0.42
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 1.642e-06 0.41
LEG9_HUMAN LGALS9 Galectin-9 1.683e-06 0.29
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 1.698e-06 0.28
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 1.991e-06 0.36
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 2.05e-06 0.29
GRIA4_RAT Gria4 Glutamate receptor 4 2.083e-06 0.35
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 2.377e-06 0.30
CAH2_BOVIN CA2 Carbonic anhydrase 2 2.977e-06 0.39
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 5.16e-06 0.28
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 6.597e-06 0.33
NMBR_HUMAN NMBR Neuromedin-B receptor 6.667e-06 0.31
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 7.345e-06 0.30

Chlorphenesin

B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 8.926e-57 0.41
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 8.959e-46 0.39
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 1.415e-37 0.41
D3W065_CHRVL cviR CviR transcriptional regulator 1.775e-36 0.29
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 6.098e-27 0.42
ANDR_MOUSE Ar Androgen receptor 2.904e-24 0.36
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 2.641e-21 0.42
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 9.477e-21 0.40
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 1.234e-19 0.41
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 5.947e-19 0.31
MP2K1_MOUSE Map2k1 Dual specificity mitogen-activated protein kinase kinase 1 8.596e-19 0.30
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 9.811e-18 0.40
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 2.734e-17 0.40
FABPI_HUMAN FABP2 Fatty acid-binding protein, intestinal 3.331e-16 0.31
ACOX1_RAT Acox1 Peroxisomal acyl-coenzyme A oxidase 1 6.439e-14 0.30
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 9.27e-14 0.47
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 4.29e-12 0.54
DYR_MYCTU folA Dihydrofolate reductase 4.619e-12 0.33
SCNNA_HUMAN SCNN1A Amiloride-sensitive sodium channel subunit alpha 9.212e-12 0.36
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 6.281e-11 0.39
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 7.683e-11 0.36
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 2.369e-10 0.32
CDK4_HUMAN CDK4 Cyclin-dependent kinase 4 6.257e-10 0.41
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 1.983e-09 0.32
MEP50_HUMAN WDR77 Methylosome protein 50 1.736e-08 0.37
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 2.122e-08 0.37
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 2.636e-08 0.31
VDR_HUMAN VDR Vitamin D3 receptor 2.946e-08 0.36
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 4.033e-08 0.39
KLK_PIG Glandular kallikrein 1.296e-07 0.30
CP26B_HUMAN CYP26B1 Cytochrome P450 26B1 3.205e-07 0.29
GYS1_HUMAN GYS1 Glycogen [starch] synthase, muscle 4.738e-07 0.31
CASR_HUMAN CASR Extracellular calcium-sensing receptor 7.376e-07 0.34
CP19A_RAT Cyp19a1 Aromatase 1.574e-06 0.30
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 1.862e-06 0.46
GP183_MOUSE Gpr183 G-protein coupled receptor 183 2.083e-06 0.35
HPPD_ARATH HPD 4-hydroxyphenylpyruvate dioxygenase 6.113e-06 0.36
AOFB_RAT Maob Amine oxidase [flavin-containing] B 8.546e-06 0.44

Levosimendan

PDE3A_HUMAN PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase A 5.029e-56 0.62
PDE3B_HUMAN PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase B 2.74e-53 0.62
E1BN64_BOVIN PDE3B Phosphodiesterase 1.001e-21 0.38
GP119_HUMAN GPR119 Glucose-dependent insulinotropic receptor 1.221e-14 0.44
PDE4B_HUMAN PDE4B cAMP-specific 3',5'-cyclic phosphodiesterase 4B 1.192e-08 0.36
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 4.619e-06 0.31

Metronidazole

A3KMY8_BOVIN GUSB Beta-glucuronidase 2.241e-48 0.55
FABH_ECOLI fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 6.575e-34 0.37
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 3.529e-27 0.41
C4LW95_ENTHI Thioredoxin reductase 4.515e-12 0.49
TYSY_HUMAN TYMS Thymidylate synthase 7.047e-12 0.50
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 4.251e-09 0.51
EGFR_HUMAN EGFR Epidermal growth factor receptor 1.912e-07 0.51
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 6.707e-07 0.29
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 8.514e-07 0.54

Misoprostol

PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 1.308e-47 0.62
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 1.785e-39 0.49
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 1.234e-31 0.49
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 6.928e-26 0.49
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 7.302e-25 0.49
MPEG1_HUMAN MPEG1 Macrophage-expressed gene 1 protein 2.074e-23 0.28
POLI_MOUSE Poli DNA polymerase iota 4.035e-23 0.28
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 5.518e-23 0.28
KPCA_RAT Prkca Protein kinase C alpha type 1.397e-22 0.31
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 8.104e-18 0.28
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 1.402e-17 0.62
POLH_HUMAN POLH DNA polymerase eta 5.551e-15 0.28
PI2R_HUMAN PTGIR Prostacyclin receptor 3.419e-14 0.62
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.624e-12 0.37
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 6.424e-12 0.35
POLK_HUMAN POLK DNA polymerase kappa 1.15e-11 0.28
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 3.953e-11 0.30
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.275e-09 0.49
LASR_PSEAE lasR Transcriptional activator protein LasR 1.325e-08 0.30
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 1.87e-08 0.40
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 1.197e-07 0.30
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 9.396e-07 0.29
GLCM_MOUSE Gba Lysosomal acid glucosylceramidase 2.145e-06 0.28
MPIP2_MOUSE Cdc25b M-phase inducer phosphatase 2 2.254e-06 0.31
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 3.409e-06 0.28

Tinidazole

A3KMY8_BOVIN GUSB Beta-glucuronidase 3.052e-43 0.49
FABH_ECOLI fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.504e-32 0.35
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.61e-24 0.37
C4LW95_ENTHI Thioredoxin reductase 1.919e-11 0.46
TYSY_HUMAN TYMS Thymidylate synthase 2.459e-11 0.47
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 2.155e-08 0.50
EGFR_HUMAN EGFR Epidermal growth factor receptor 8.875e-07 0.50
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 9.977e-07 0.54

Demecarium

PA2A1_NAJMO Acidic phospholipase A2 CM-I 2.89e-41 0.33
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 5.657e-34 0.49
ACES_HUMAN ACHE Acetylcholinesterase 1.756e-24 0.71
CHLE_HUMAN BCHE Cholinesterase 6.681e-19 0.42
ACES_BOVIN ACHE Acetylcholinesterase 5.024e-13 0.50
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 7.204e-12 0.32
LSS_HUMAN LSS Lanosterol synthase 1.908e-10 0.30
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 2.377e-10 0.43
AOFB_RAT Maob Amine oxidase [flavin-containing] B 5.157e-10 0.49
Q9JKC1_RAT Bche Carboxylic ester hydrolase 3.949e-09 0.45
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 7.649e-09 0.33
CAS1_ARATH CAS1 Cycloartenol synthase 1.007e-08 0.30
ERG7_YEAST ERG7 Lanosterol synthase 1.007e-08 0.30
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.983e-08 0.35
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 9.696e-08 0.35
CHLE_HORSE BCHE Cholinesterase 1.884e-07 0.50
ACES_RAT Ache Acetylcholinesterase 1.026e-06 0.71
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 1.42e-06 0.34
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 4.202e-06 0.31
HRH3_CAVPO HRH3 Histamine H3 receptor 4.43e-06 0.37
PA21B_PIG PLA2G1B Phospholipase A2, major isoenzyme 7.916e-06 0.37

Emtricitabine

DCK_HUMAN DCK Deoxycytidine kinase 1.347e-39 0.36
TYSY_MYCTU thyA Thymidylate synthase ThyA 2.095e-36 0.29
KITH_VZVD TK Thymidine kinase 2.064e-19 0.30
ADCY5_RAT Adcy5 Adenylate cyclase type 5 4.118e-18 0.33
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 1.167e-12 0.34
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 3.144e-12 0.30
THYX_MYCTU thyX Flavin-dependent thymidylate synthase 3.108e-09 0.29
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 3.419e-06 0.64
DPOLB_HUMAN POLB DNA polymerase beta 7.269e-06 0.34

Methylphenobarbital

ADA1B_MOUSE Adra1b Alpha-1B adrenergic receptor 4.167e-32 0.33
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 1.087e-09 0.28
Q17SB2_PLAFA Plasmepsin 4 7.347e-08 0.31

Remifentanil

HCN1_HUMAN HCN1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 5.398e-31 0.30
HCN4_HUMAN HCN4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 1.752e-24 0.30
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 8.173e-23 0.36
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 1.428e-21 0.35
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 4.292e-21 0.34
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 3.084e-19 0.36
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.335e-18 0.35
OPRM_RAT Oprm1 Mu-type opioid receptor 3.664e-15 0.77
OPRX_HUMAN OPRL1 Nociceptin receptor 4.036e-12 0.53
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 1.761e-11 0.30
CALM_BOVIN CALM Calmodulin 6.878e-11 0.29
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 7.404e-11 0.31
S12A5_RAT Slc12a5 Solute carrier family 12 member 5 1.52e-10 0.30
CP74A_ARATH CYP74A Allene oxide synthase, chloroplastic 3.619e-10 0.30
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 3.625e-10 0.31
OPRM_HUMAN OPRM1 Mu-type opioid receptor 3.771e-10 0.77
PDIA1_HUMAN P4HB Protein disulfide-isomerase 7.004e-10 0.30
OPRM_CAVPO OPRM1 Mu-type opioid receptor 8.857e-10 0.77
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 9.209e-10 0.31
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 4.731e-09 0.32
KKCC2_HUMAN CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 1.073e-08 0.31
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 2.287e-08 0.30
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 2.86e-08 0.32
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 3.333e-08 0.31
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 3.333e-08 0.31
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 3.333e-08 0.31
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 3.333e-08 0.31
OPRD_HUMAN OPRD1 Delta-type opioid receptor 6.475e-08 0.77
MYO3B_HUMAN MYO3B Myosin-IIIb 8.088e-08 0.31
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 1.767e-07 0.31
SRPK2_HUMAN SRPK2 SRSF protein kinase 2 1.767e-07 0.31
STK11_HUMAN STK11 Serine/threonine-protein kinase STK11 1.767e-07 0.31
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 3.025e-07 0.33
PRP4B_HUMAN PRPF4B Serine/threonine-protein kinase PRP4 homolog 3.541e-07 0.31
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 4.547e-07 0.30
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 6.604e-07 0.31
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 6.604e-07 0.31
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 8.084e-07 0.32
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 8.493e-07 0.32
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 8.517e-07 0.31
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 1.159e-06 0.31
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 1.159e-06 0.31
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 1.159e-06 0.31
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 1.159e-06 0.31
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 1.933e-06 0.31
OPRM_MOUSE Oprm1 Mu-type opioid receptor 1.975e-06 0.38
Q63380_RAT NET Transporter 2.213e-06 0.32
HRH3_CAVPO HRH3 Histamine H3 receptor 2.415e-06 0.31
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.839e-06 0.31
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 3.082e-06 0.31
INSRR_HUMAN INSRR Insulin receptor-related protein 3.082e-06 0.31
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 3.082e-06 0.31
MYLK4_HUMAN MYLK4 Myosin light chain kinase family member 4 3.082e-06 0.31
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 3.273e-06 0.29
HRH1_CAVPO HRH1 Histamine H1 receptor 3.555e-06 0.32
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 4.73e-06 0.31
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 4.73e-06 0.31
PI42B_HUMAN PIP4K2B Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 4.73e-06 0.31
CCR5_MACFA CCR5 C-C chemokine receptor type 5 4.993e-06 0.28
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 5.557e-06 0.29
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 6.275e-06 0.77
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 7.02e-06 0.31
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 7.02e-06 0.31
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 8.827e-06 0.29

Famotidine

HRH2_RAT Hrh2 Histamine H2 receptor 1.457e-30 0.33
CCKAR_MOUSE Cckar Cholecystokinin receptor type A 2.708e-27 0.32
HRH2_CAVPO HRH2 Histamine H2 receptor 3.212e-11 0.47
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 2.165e-08 0.32
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 5.039e-07 0.43

Isosorbide_dinitrate

GSHR_HUMAN GSR Glutathione reductase, mitochondrial 1.161e-26 0.48
CHLE_HUMAN BCHE Cholinesterase 2.446e-06 0.66

Etretinate

RABP1_CHICK CRABP1 Cellular retinoic acid-binding protein 1 1.081e-23 0.31
RXRA_RAT Rxra Retinoic acid receptor RXR-alpha 5.602e-19 0.31
RARA_MOUSE Rara Retinoic acid receptor alpha 1.008e-17 0.31
RARG_HUMAN RARG Retinoic acid receptor gamma 2.22e-16 0.34
RXRA_HUMAN RXRA Retinoic acid receptor RXR-alpha 3.553e-15 0.34
RARG_MOUSE Rarg Retinoic acid receptor gamma 1.71e-14 0.31
RARB_MOUSE Rarb Retinoic acid receptor beta 6.961e-14 0.31
RABP1_MOUSE Crabp1 Cellular retinoic acid-binding protein 1 3.922e-13 0.29
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 7.838e-12 0.29
RABP2_MOUSE Crabp2 Cellular retinoic acid-binding protein 2 9.7e-12 0.29
RXRA_MOUSE Rxra Retinoic acid receptor RXR-alpha 2.276e-10 0.31
MTSI_SPISQ sssIM CPG DNA methylase 3.055e-09 0.29
RXRB_HUMAN RXRB Retinoic acid receptor RXR-beta 7.655e-09 0.34
RXRG_HUMAN RXRG Retinoic acid receptor RXR-gamma 8.477e-09 0.34
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 2.077e-07 0.29
CYSP_PLAFA Trophozoite cysteine proteinase 4.056e-07 0.29
RARA_HUMAN RARA Retinoic acid receptor alpha 8.807e-07 0.34

Chlorothiazide

CAH3_HUMAN CA3 Carbonic anhydrase 3 4.925e-22 0.36
ABCC8_RAT Abcc8 ATP-binding cassette sub-family C member 8 2.969e-18 0.31
Q5TU56_ANOGA 1272966 Carbonic anhydrase 2.015e-17 0.55
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 5.551e-16 0.55
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 3.986e-14 0.47
CAH6_HUMAN CA6 Carbonic anhydrase 6 1.135e-13 0.47
CAH13_HUMAN CA13 Carbonic anhydrase 13 3.462e-12 0.36
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 5.267e-12 0.47
B2V8E3_SULSY Carbonate dehydratase 1.715e-11 0.55
Q31FD6_HYDCU Carbonic anhydrase, alpha family 1.715e-11 0.55
CAH4_BOVIN CA4 Carbonic anhydrase 4 3.369e-11 0.35
A6YCJ1_9METZ Astrosclerin-3 6.683e-11 0.55
CAH1_HUMAN CA1 Carbonic anhydrase 1 8.418e-11 0.55
CAH2_HUMAN CA2 Carbonic anhydrase 2 6.93e-10 0.55
CAH4_HUMAN CA4 Carbonic anhydrase 4 2.719e-09 0.47
CAH12_HUMAN CA12 Carbonic anhydrase 12 3.674e-09 0.47
CAH9_HUMAN CA9 Carbonic anhydrase 9 4.604e-08 0.47
CAH14_HUMAN CA14 Carbonic anhydrase 14 5.257e-08 0.47
CAH7_HUMAN CA7 Carbonic anhydrase 7 8.854e-08 0.51
CAH_METTE Carbonic anhydrase 9.875e-07 0.33
CAH13_MOUSE Ca13 Carbonic anhydrase 13 1.403e-06 0.47

Cyclobenzaprine

HRH1_CAVPO HRH1 Histamine H1 receptor 2.881e-19 0.48
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 3.313e-19 0.32
ASM_HUMAN SMPD1 Sphingomyelin phosphodiesterase 1.599e-14 0.36
ANM1_RAT Prmt1 Protein arginine N-methyltransferase 1 1.275e-11 0.28
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 2.686e-11 0.52
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 6.769e-11 0.36
5HT2C_MOUSE Htr2c 5-hydroxytryptamine receptor 2C 2.944e-09 0.31
HRH1_RAT Hrh1 Histamine H1 receptor 1.516e-07 0.63
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.088e-06 0.29
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 5.252e-06 0.28
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 6.094e-06 0.31
DRD5_HUMAN DRD5 D(1B) dopamine receptor 9.101e-06 0.63

Didanosine

SYI_ECOLI ileS Isoleucine--tRNA ligase 4.879e-18 0.29
PPM1B_HUMAN PPM1B Protein phosphatase 1B 4.822e-17 0.30
AA1R_RAT Adora1 Adenosine receptor A1 3.331e-16 0.36
IUNH_CRIFA IUNH Inosine-uridine preferring nucleoside hydrolase 4.441e-16 0.31
O15727_TRYBB Inosine-adenosine-guanosine-nucleoside hydrolase 4.441e-16 0.31
Q4VQ11_PIG Adenosine receptor A1 4.441e-16 0.31
ADA_BOVIN ADA Adenosine deaminase 2.22e-15 0.50
Q9HX69_PSEAE rocR RocR 7.105e-15 0.28
Q8AWE3_CHICK Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B 8.293e-14 0.30
AA1R_CAVPO ADORA1 Adenosine receptor A1 1.295e-12 0.33
PNPH_BOVIN PNP Purine nucleoside phosphorylase 6.643e-11 0.30
Q8T9Z7_PLAFA PNP Purine nucleoside phosphorylase 1.374e-10 0.30
ADCY2_RAT Adcy2 Adenylate cyclase type 2 1.522e-10 0.28
ADA_HUMAN ADA Adenosine deaminase 2.281e-09 0.30
PNPH_HUMAN PNP Purine nucleoside phosphorylase 4.794e-09 0.30
HCAR1_HUMAN HCAR1 Hydroxycarboxylic acid receptor 1 9.562e-09 0.29
AA2AR_RAT Adora2a Adenosine receptor A2a 1.908e-08 0.31
AA1R_CHICK ADORA1 Adenosine receptor A1 9.412e-08 0.30
ADCY5_RAT Adcy5 Adenylate cyclase type 5 3.462e-06 0.29
AA3R_RAT Adora3 Adenosine receptor A3 3.946e-06 0.33
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 6.544e-06 0.31
P2RX1_RAT P2rx1 P2X purinoceptor 1 7.451e-06 0.30

Cysteamine

AMPB_RAT Rnpep Aminopeptidase B 2.38e-07 0.30
CAH3_HUMAN CA3 Carbonic anhydrase 3 5.692e-06 0.33

Temozolomide

PLK2_HUMAN PLK2 Serine/threonine-protein kinase PLK2 3.361e-07 0.28

Mechlorethamine

S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 5.796e-07 0.32