Results of Job: search_ff2cab60-9fbf-40ee-950b-2d90c12190b6

Query Target Key Target Name Description P-Value MaxTC

Cyclic-guanosine-monophosphate-(cGMP)

Q9HX69_PSEAE rocR RocR 8.25e-165 1.00
E1BN64_BOVIN PDE3B Phosphodiesterase 3.59e-28 1.00
OXGR1_RAT Oxgr1 2-oxoglutarate receptor 1 1.276e-140 0.36
IF4E_RABIT EIF4E Eukaryotic translation initiation factor 4E 2.115e-107 0.45
IF4E_MOUSE Eif4e Eukaryotic translation initiation factor 4E 2.136e-98 0.35
HPRT_HUMAN HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 5.012e-87 0.54
AA1R_RAT Adora1 Adenosine receptor A1 1.874e-84 0.36
RASK_HUMAN KRAS GTPase KRas 1.971e-81 0.44
Q8TA74_HEMPU Ryanodine receptor 7.373e-78 0.48
FUT6_HUMAN FUT6 Alpha-(1,3)-fucosyltransferase 6 6.52e-75 0.37
AA2AR_RAT Adora2a Adenosine receptor A2a 3.463e-70 0.38
P2RY1_RAT P2ry1 P2Y purinoceptor 1 6.015e-70 0.34
MTAP_MOUSE Mtap S-methyl-5'-thioadenosine phosphorylase 2.95e-69 0.30
SAHH_RAT Ahcy Adenosylhomocysteinase 4.603e-64 0.33
C3SIU2_ECOLX metJ Met repressor 3.722e-60 0.32
KTHY_HUMAN DTYMK Thymidylate kinase 4.022e-57 0.34
SAHH_HUMAN AHCY Adenosylhomocysteinase 9.992e-55 0.35
PNPH_HUMAN PNP Purine nucleoside phosphorylase 3.486e-50 0.43
AA1R_CAVPO ADORA1 Adenosine receptor A1 1.267e-48 0.35
RNAS1_HUMAN RNASE1 Ribonuclease pancreatic 8.123e-47 0.30
RNAS2_HUMAN RNASE2 Non-secretory ribonuclease 8.123e-47 0.30
PANE_ECOLI panE 2-dehydropantoate 2-reductase 3.154e-45 0.28
HGPRT_MYCTU hpt Hypoxanthine-guanine phosphoribosyltransferase 1.968e-44 0.35
UL97_HCMVA UL97 Serine/threonine protein kinase UL97 2.49e-44 0.35
AA3R_HUMAN ADORA3 Adenosine receptor A3 4.3e-44 0.38
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 1.627e-43 0.33
KMT5C_HUMAN KMT5C Histone-lysine N-methyltransferase KMT5C 6.244e-40 0.32
SETB1_HUMAN SETDB1 Histone-lysine N-methyltransferase SETDB1 6.244e-40 0.32
ENPL_PIG HSP90B1 Endoplasmin 7.545e-40 0.32
MSHC_MYCTU mshC L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 1.551e-39 0.31
P2RX5_RAT P2rx5 P2X purinoceptor 5 1.841e-39 0.33
P2RX6_RAT P2rx6 P2X purinoceptor 6 1.841e-39 0.33
SYS_ECOLI serS Serine--tRNA ligase 4.474e-39 0.31
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 4.659e-39 0.36
XGPT_ECOLI gpt Xanthine phosphoribosyltransferase 5.748e-39 0.31
P2RY4_RAT P2ry4 P2Y purinoceptor 4 1.214e-38 0.32
HSP7C_BOVIN HSPA8 Heat shock cognate 71 kDa protein 2.276e-38 0.30
WALK_STAAU walK Sensor protein kinase WalK 2.276e-38 0.30
SYD_ECOLI aspS Aspartate--tRNA ligase 3.458e-38 0.30
MACD1_HUMAN MACROD1 ADP-ribose glycohydrolase MACROD1 1.917e-37 0.30
MACD2_HUMAN MACROD2 ADP-ribose glycohydrolase MACROD2 1.917e-37 0.30
HARS1_HUMAN HARS1 Histidine--tRNA ligase, cytoplasmic 4.269e-37 0.29
IUNH_CRIFA IUNH Inosine-uridine preferring nucleoside hydrolase 5.919e-37 0.43
O15727_TRYBB Inosine-adenosine-guanosine-nucleoside hydrolase 5.919e-37 0.43
SYQ_HUMAN QARS1 Glutamine--tRNA ligase 6.038e-37 0.30
RN5A_HUMAN RNASEL 2-5A-dependent ribonuclease 2.43e-36 0.29
METK2_RAT Mat2a S-adenosylmethionine synthase isoform type-2 3.875e-36 0.29
SYY_ECOLI tyrS Tyrosine--tRNA ligase 3.875e-36 0.29
ENPP1_RAT Enpp1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 5.657e-36 0.30
Q9HWG3_PSEAE pchD Pyochelin biosynthesis protein PchD 6.145e-36 0.28
Q3ZDS5_9HEPC NS5B 8.132e-33 0.41
AA3R_RAT Adora3 Adenosine receptor A3 1.128e-32 0.40
SAHH_MOUSE Ahcy Adenosylhomocysteinase 2.045e-31 0.31
PARG_BOVIN PARG Poly(ADP-ribose) glycohydrolase 1.231e-30 0.30
DOT1L_HUMAN DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 3.15e-30 0.32
AA1R_HUMAN ADORA1 Adenosine receptor A1 8.379e-30 0.36
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 1.028e-29 0.33
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 4.246e-29 0.45
P96884_MYCTO birA BirA bifunctional protein 4.68e-29 0.29
AA1R_CHICK ADORA1 Adenosine receptor A1 7.188e-28 0.32
KAD3_RAT Ak3 GTP:AMP phosphotransferase AK3, mitochondrial 2.614e-25 0.31
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 8.186e-25 0.32
SYL_ECOLI leuS Leucine--tRNA ligase 2.656e-24 0.30
ADCY5_RAT Adcy5 Adenylate cyclase type 5 3.103e-24 0.33
ANM7_HUMAN PRMT7 Protein arginine N-methyltransferase 7 3.317e-24 0.30
MBTA_MYCTU mbtA Salicyl-AMP ligase / salicyl-S-ArCP synthetase 4.149e-24 0.33
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 9.196e-24 0.38
RN5A_MOUSE Rnasel 2-5A-dependent ribonuclease 2.117e-23 0.29
P2Y11_HUMAN P2RY11 P2Y purinoceptor 11 3.446e-23 0.30
PQSA_PSEAE pqsA Anthranilate--CoA ligase 3.817e-23 0.28
NADK_HUMAN NADK NAD kinase 3.915e-23 0.28
SYRC_HUMAN RARS1 Arginine--tRNA ligase, cytoplasmic 4.989e-23 0.28
DCAM_HUMAN AMD1 S-adenosylmethionine decarboxylase proenzyme 2.529e-21 0.30
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 3.65e-21 0.32
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 3.919e-21 0.33
PNPH_MOUSE Pnp Purine nucleoside phosphorylase 6.654e-21 0.33
IF4E_HUMAN EIF4E Eukaryotic translation initiation factor 4E 2.808e-20 0.34
PNPH_RAT Pnp Purine nucleoside phosphorylase 1.175e-19 0.38
KAD2_RAT Ak2 Adenylate kinase 2, mitochondrial 1.335e-19 0.31
METK1_RAT Mat1a S-adenosylmethionine synthase isoform type-1 3.429e-19 0.30
KITH_RAT Tk1 Thymidine kinase, cytosolic 4.43e-19 0.30
PARG_HUMAN PARG Poly(ADP-ribose) glycohydrolase 4.884e-19 0.30
P2RX4_RAT P2rx4 P2X purinoceptor 4 2.335e-18 0.33
SYI_ECOLI ileS Isoleucine--tRNA ligase 6.109e-18 0.28
PYRF_YEAST URA3 Orotidine 5'-phosphate decarboxylase 1.882e-17 0.33
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 1.11e-16 0.33
P2RX1_RAT P2rx1 P2X purinoceptor 1 1.11e-16 0.36
Q4VQ11_PIG Adenosine receptor A1 1.11e-16 0.32
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 1.11e-16 0.51
GPR17_HUMAN GPR17 Uracil nucleotide/cysteinyl leukotriene receptor 3.331e-16 0.32
RAB7A_HUMAN RAB7A Ras-related protein Rab-7a 3.331e-16 0.52
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 1.11e-15 0.51
DNPH1_RAT Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 1.11e-15 0.30
DNPH1_HUMAN DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 3.22e-15 0.30
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 8.216e-15 0.38
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 8.66e-15 0.30
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 8.882e-15 0.32
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 1.033e-14 0.32
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 2.043e-14 0.33
O39930_9HEPC NS5b RNA-directed RNA polymerase 2.542e-14 0.49
PNPH_BOVIN PNP Purine nucleoside phosphorylase 3.053e-14 0.36
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 5.096e-14 0.33
I6YFP0_MYCTU birA Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase) 7.572e-14 0.28
ADA_BOVIN ADA Adenosine deaminase 9.115e-14 0.33
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 4.911e-13 0.32
HPPK_ECOLI folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 9.478e-13 0.38
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 1.243e-12 0.36
DPOLB_HUMAN POLB DNA polymerase beta 1.424e-12 0.43
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 6.016e-12 0.29
SUV91_HUMAN SUV39H1 Histone-lysine N-methyltransferase SUV39H1 9.554e-12 0.32
AA1R_MOUSE Adora1 Adenosine receptor A1 1.579e-11 0.32
ADCY2_RAT Adcy2 Adenylate cyclase type 2 2.276e-11 0.31
SYTC_HUMAN TARS1 Threonine--tRNA ligase 1, cytoplasmic 3.371e-11 0.29
SYMC_HUMAN MARS1 Methionine--tRNA ligase, cytoplasmic 4.415e-11 0.32
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 1.74e-10 0.36
DCPS_HUMAN DCPS m7GpppX diphosphatase 1.85e-10 0.45
PANC_MYCTU panC Pantothenate synthetase 5.506e-10 0.30
G3P_HUMAN GAPDH Glyceraldehyde-3-phosphate dehydrogenase 9.631e-10 0.34
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 2.494e-09 0.29
DCAM_RAT Amd1 S-adenosylmethionine decarboxylase proenzyme 3.131e-09 0.30
KMT2A_HUMAN KMT2A Histone-lysine N-methyltransferase 2A 6.444e-09 0.32
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 1.472e-08 0.36
TGT_ZYMMO tgt Queuine tRNA-ribosyltransferase 1.751e-08 0.28
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 1.817e-08 0.34
P2RX2_RAT P2rx2 P2X purinoceptor 2 2.229e-08 0.33
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 3.706e-08 0.43
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 5.387e-08 0.32
BIP_HUMAN HSPA5 Endoplasmic reticulum chaperone BiP 9.036e-08 0.30
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 9.771e-08 0.30
EZH1_HUMAN EZH1 Histone-lysine N-methyltransferase EZH1 2.123e-07 0.32
INMT_HUMAN INMT Indolethylamine N-methyltransferase 2.123e-07 0.32
AA3R_MOUSE Adora3 Adenosine receptor A3 3.253e-07 0.29
TYPH_HUMAN TYMP Thymidine phosphorylase 3.975e-07 0.31
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 1.905e-06 0.29
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 1.988e-06 0.32
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 2.012e-06 0.32
KITH_HUMAN TK1 Thymidine kinase, cytosolic 2.264e-06 0.41
P2Y12_RAT P2ry12 P2Y purinoceptor 12 2.286e-06 0.33
5NTD_RAT Nt5e 5'-nucleotidase 2.295e-06 0.30
IMDH1_HUMAN IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 2.511e-06 0.31
5NTD_HUMAN NT5E 5'-nucleotidase 4.256e-06 0.29
SYT_YERPE thrS Threonine--tRNA ligase 5.785e-06 0.29
ENPL_CANLF HSP90B1 Endoplasmin 6.792e-06 0.32
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 8.361e-06 0.47
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 8.86e-06 0.40
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 9.078e-06 0.32

Luteolin

TOP1_RAT Top1 DNA topoisomerase 1 2.9e-124 1.00
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 8.429e-80 1.00
ARGI1_RAT Arg1 Arginase-1 2.714e-79 1.00
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 1.2e-72 1.00
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 3.365e-60 1.00
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 8.549e-55 1.00
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 9.528e-52 1.00
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 1.744e-46 1.00
NOX4_HUMAN NOX4 NADPH oxidase 4 2.696e-24 1.00
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 1.878e-21 1.00
LGUL_HUMAN GLO1 Lactoylglutathione lyase 4.658e-21 1.00
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 6.735e-20 1.00
NANH_CLOPF nanH Sialidase 3.058e-19 1.00
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 3.331e-16 1.00
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 2.776e-15 1.00
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 7.883e-15 1.00
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 2.778e-13 1.00
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 1.304e-12 1.00
TTHY_HUMAN TTR Transthyretin 1.717e-12 1.00
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 3.17e-12 1.00
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 1.001e-11 1.00
CAH4_HUMAN CA4 Carbonic anhydrase 4 4.486e-11 1.00
A4_HUMAN APP Amyloid-beta precursor protein 1.802e-10 1.00
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 2.402e-09 1.00
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 2.436e-09 1.00
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 4.045e-09 1.00
CAH7_HUMAN CA7 Carbonic anhydrase 7 6.878e-09 1.00
GPR35_HUMAN GPR35 G-protein coupled receptor 35 8.115e-09 1.00
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 1.766e-08 1.00
FABI_ECOLI fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 1.148e-07 1.00
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 2.022e-06 1.00
AA1R_RAT Adora1 Adenosine receptor A1 2.637e-05 1.00
CAH12_HUMAN CA12 Carbonic anhydrase 12 0.000256 1.00
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 0.001381 1.00
CSK2B_HUMAN CSNK2B Casein kinase II subunit beta 0.002135 1.00
MMP12_HUMAN MMP12 Macrophage metalloelastase 0.003448 1.00
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 0.008857 1.00
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 0.01442 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.04025 1.00
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 0.07945 1.00
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 0.09908 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 0.2268 1.00
DPP4_HUMAN DPP4 Dipeptidyl peptidase 4 0.3131 1.00
MMP2_HUMAN MMP2 72 kDa type IV collagenase 0.6846 1.00
O96394_LEIAM Arginase 1.967e-85 0.60
CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 2.175e-82 0.42
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 2.714e-79 0.62
OPRD_PIG OPRD1 Delta-type opioid receptor 5.351e-78 0.62
AK1CL_MOUSE Akr1c21 Aldo-keto reductase family 1 member C21 2.514e-74 0.60
DDL_HELPH ddl D-alanine--D-alanine ligase 2.514e-74 0.60
VE6_HPV16 E6 Protein E6 1.255e-69 0.45
BGLR_RAT Gusb Beta-glucuronidase 2.074e-69 0.78
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 1.266e-60 0.55
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 6.416e-59 0.60
FPS_FUJSV V-FPS Tyrosine-protein kinase transforming protein Fps 5.734e-57 0.45
FAS_CHICK FASN Fatty acid synthase 3.635e-53 0.42
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 6.992e-50 0.62
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 1.509e-47 0.60
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 5.601e-34 0.42
PDIA1_HUMAN P4HB Protein disulfide-isomerase 1.433e-32 0.43
PLGF_HUMAN PGF Placenta growth factor 5.409e-32 0.62
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 6.255e-32 0.45
CBS_HUMAN CBS Cystathionine beta-synthase 7.886e-30 0.56
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 2.376e-29 0.60
LYSC1_RAT Lyz1 Lysozyme C-1 3.125e-29 0.36
RMLD_MYCTU rmlD dTDP-4-dehydrorhamnose reductase 1.52e-28 0.35
AMY1A_HUMAN AMY1A Alpha-amylase 1 3.9e-28 0.55
SYN1_BOVIN SYN1 Synapsin-1 5.234e-27 0.43
PRKDC_MOUSE Prkdc DNA-dependent protein kinase catalytic subunit 1.481e-26 0.33
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 2.603e-26 0.67
R1AB_SARS rep Replicase polyprotein 1ab 4.406e-25 0.62
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 5.456e-23 0.29
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 6.966e-22 0.42
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 6.654e-21 0.33
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 8.544e-20 0.78
DPO1_THEAQ polA DNA polymerase I, thermostable 1.464e-19 0.52
PON1_HUMAN PON1 Serum paraoxonase/arylesterase 1 2.886e-19 0.31
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 9.774e-19 0.62
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 1.386e-18 0.60
MDH_THETH mdh Malate dehydrogenase 2.972e-18 0.60
PERL_BOVIN LPO Lactoperoxidase 2.972e-18 0.60
ACES_RAT Ache Acetylcholinesterase 1.162e-17 0.43
Q7ZJM1_9HIV1 pol Integrase 1.515e-17 0.78
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 1.892e-17 0.37
DHPR_RAT Qdpr Dihydropteridine reductase 2.727e-17 0.32
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 2.854e-17 0.64
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 4.39e-17 0.60
DHPR_HUMAN QDPR Dihydropteridine reductase 2.22e-16 0.32
TERT_HUMAN TERT Telomerase reverse transcriptase 2.22e-16 0.52
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 4.441e-16 0.78
P89582_9HIV2 pol Integrase 3.442e-15 0.33
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 8.66e-15 0.48
SYUA_HUMAN SNCA Alpha-synuclein 1.121e-14 0.43
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 1.894e-13 0.60
CP2C8_HUMAN CYP2C8 Cytochrome P450 2C8 2.939e-13 0.60
ESR2_HUMAN ESR2 Estrogen receptor beta 3.177e-13 0.78
REST_BORBU resT Telomere resolvase ResT 4.431e-13 0.32
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 3.949e-12 0.61
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 7.733e-12 0.60
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.158e-11 0.60
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 1.418e-11 0.37
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 1.851e-11 0.55
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 4.328e-11 0.60
Q5J463_SALCH tem-1 Beta-lactamase 7.011e-11 0.30
CALM1_HUMAN CALM1 Calmodulin-1 7.633e-11 0.39
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 1.204e-10 0.62
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 1.215e-10 0.78
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 1.409e-10 0.45
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 1.445e-10 0.61
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 1.735e-10 0.48
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 1.947e-10 0.60
IL2_HUMAN IL2 Interleukin-2 4.317e-10 0.56
AHR_HUMAN AHR Aryl hydrocarbon receptor 8.514e-10 0.41
ESR1_HUMAN ESR1 Estrogen receptor 4.019e-09 0.78
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 9.402e-09 0.33
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1.402e-08 0.45
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.672e-08 0.30
PERM_HUMAN MPO Myeloperoxidase 7.234e-08 0.78
CAH3_HUMAN CA3 Carbonic anhydrase 3 1.014e-07 0.60
DCOR_HUMAN ODC1 Ornithine decarboxylase 1.199e-07 0.28
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 1.342e-07 0.60
Q43570_TOBAC NtBBF1.1 Zn finger protein 2.116e-07 0.30
ANDR_HUMAN AR Androgen receptor 2.442e-07 0.78
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 3.044e-07 0.32
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 3.288e-07 0.48
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 4.931e-07 0.60
DPP4_PIG DPP4 Dipeptidyl peptidase 4 7.041e-07 0.48
TYRO_HUMAN TYR Tyrosinase 7.562e-07 0.64
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 8.143e-07 0.78
CLK1_MOUSE Clk1 Dual specificity protein kinase CLK1 8.854e-07 0.32
ULA1_HUMAN NAE1 NEDD8-activating enzyme E1 regulatory subunit 1.115e-06 0.53
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 1.35e-06 0.48
TAU_HUMAN MAPT Microtubule-associated protein tau 1.69e-06 0.45
5NTD_RAT Nt5e 5'-nucleotidase 2.101e-06 0.60
B4URF0_I33A0 Neuraminidase 4.405e-06 0.60
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 4.73e-06 0.60
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 5.091e-06 0.28
IL5_MOUSE Il5 Interleukin-5 5.429e-06 0.31

Diosmetin

CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 8.431e-86 1.00
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 1.046e-21 1.00
TOP1_RAT Top1 DNA topoisomerase 1 5.161e-89 0.71
CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 3.621e-85 0.48
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 9.401e-75 0.71
OPRD_PIG OPRD1 Delta-type opioid receptor 6.105e-66 0.53
ACES_RAT Ache Acetylcholinesterase 3.083e-62 0.58
VE6_HPV16 E6 Protein E6 1.873e-61 0.40
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 1.417e-60 0.71
BGLR_RAT Gusb Beta-glucuronidase 2.926e-60 0.67
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 6.63e-60 0.71
ARGI1_RAT Arg1 Arginase-1 6.95e-57 0.71
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 1.29e-55 0.49
AK1CL_MOUSE Akr1c21 Aldo-keto reductase family 1 member C21 4.144e-54 0.43
DDL_HELPH ddl D-alanine--D-alanine ligase 4.144e-54 0.43
O96394_LEIAM Arginase 3.341e-52 0.43
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 8.902e-51 0.71
FPS_FUJSV V-FPS Tyrosine-protein kinase transforming protein Fps 3.077e-50 0.40
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 1.305e-49 0.44
Q0PJ46_PLAFA LDH Lactate dehydrogenase 1.931e-47 0.33
FAS_CHICK FASN Fatty acid synthase 3.059e-43 0.34
CBS_HUMAN CBS Cystathionine beta-synthase 4.613e-41 0.58
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 7.531e-41 0.34
MDHC_PIG MDH1 Malate dehydrogenase, cytoplasmic 6.635e-40 0.33
Q6VVP7_PLAFA Malate dehydrogenase 6.635e-40 0.33
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 2.149e-39 0.71
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 4.464e-36 0.45
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 4.464e-36 0.45
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 1.073e-34 0.43
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.926e-33 0.71
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 9.433e-33 0.62
PDIA1_HUMAN P4HB Protein disulfide-isomerase 4.745e-31 0.37
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 9.132e-31 0.48
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 4.406e-30 0.37
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 9.76e-29 0.31
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 1.251e-28 0.73
PLGF_HUMAN PGF Placenta growth factor 4.032e-27 0.53
LYSC1_RAT Lyz1 Lysozyme C-1 5.085e-26 0.32
AMY1A_HUMAN AMY1A Alpha-amylase 1 1.009e-24 0.48
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.024e-24 0.67
PRKDC_MOUSE Prkdc DNA-dependent protein kinase catalytic subunit 3.794e-24 0.30
RMLD_MYCTU rmlD dTDP-4-dehydrorhamnose reductase 7.498e-24 0.29
R1AB_SARS rep Replicase polyprotein 1ab 1.197e-21 0.53
MDHM_PIG MDH2 Malate dehydrogenase, mitochondrial 2.145e-20 0.33
ACES_ELEEL ache Acetylcholinesterase 5.662e-20 0.39
NOX4_HUMAN NOX4 NADPH oxidase 4 5.835e-20 0.71
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 8.317e-20 0.43
DPO1_THEAQ polA DNA polymerase I, thermostable 1.621e-19 0.49
SYN1_BOVIN SYN1 Synapsin-1 1.913e-19 0.31
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 2.087e-19 0.37
IL2_HUMAN IL2 Interleukin-2 4.062e-19 0.45
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.771e-18 0.71
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 4.471e-18 0.71
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 6.315e-18 0.58
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 1.11e-16 0.71
T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 3.331e-16 0.31
LGUL_HUMAN GLO1 Lactoylglutathione lyase 4.441e-16 0.71
NANH_CLOPF nanH Sialidase 3.775e-15 0.71
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 4.552e-15 0.56
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 5.44e-15 0.43
REST_BORBU resT Telomere resolvase ResT 1.799e-14 0.36
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 5.451e-14 0.71
Q7ZJM1_9HIV1 pol Integrase 6.928e-14 0.67
TERT_HUMAN TERT Telomerase reverse transcriptase 1.25e-13 0.50
P89582_9HIV2 pol Integrase 1.372e-13 0.30
MDH_THETH mdh Malate dehydrogenase 1.913e-13 0.43
PERL_BOVIN LPO Lactoperoxidase 1.913e-13 0.43
Q43570_TOBAC NtBBF1.1 Zn finger protein 2.262e-13 0.29
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 4.124e-13 0.42
PDK4_HUMAN PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 6.449e-13 0.28
A4_HUMAN APP Amyloid-beta precursor protein 9.233e-13 0.71
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 1.353e-12 0.43
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 2.023e-12 0.48
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 2.744e-12 0.71
Q5J463_SALCH tem-1 Beta-lactamase 3.88e-12 0.36
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 9.893e-12 0.73
TTHY_HUMAN TTR Transthyretin 1.033e-11 0.71
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 4.176e-11 0.34
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4.428e-11 0.54
DCOR_HUMAN ODC1 Ornithine decarboxylase 4.712e-11 0.42
ESR2_HUMAN ESR2 Estrogen receptor beta 4.742e-11 0.67
TLR1_MOUSE Tlr1 Toll-like receptor 1 5.879e-11 0.30
TLR2_MOUSE Tlr2 Toll-like receptor 2 5.879e-11 0.30
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 9.074e-11 0.43
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.575e-10 0.43
PDK3_HUMAN PDK3 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 1.647e-10 0.28
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 2.245e-10 0.71
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 3.547e-10 0.32
CAH7_HUMAN CA7 Carbonic anhydrase 7 5.89e-10 0.71
CP2C8_HUMAN CYP2C8 Cytochrome P450 2C8 8.164e-10 0.43
CALM1_HUMAN CALM1 Calmodulin-1 1.109e-09 0.35
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.792e-09 0.36
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 1.824e-09 0.40
CAH13_HUMAN CA13 Carbonic anhydrase 13 1.826e-09 0.40
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 2.63e-09 0.42
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 3.217e-09 0.67
IMPA1_BOVIN IMPA1 Inositol monophosphatase 1 3.304e-09 0.31
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 4.304e-09 0.53
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 6.027e-09 0.48
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 7.143e-09 0.44
CAH4_HUMAN CA4 Carbonic anhydrase 4 7.423e-09 0.71
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 7.982e-09 0.73
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 8.168e-09 0.45
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 8.814e-09 0.43
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 1.246e-08 0.44
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 1.455e-08 0.71
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.594e-08 0.71
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 2.174e-08 0.71
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 3.088e-08 0.43
ESR1_HUMAN ESR1 Estrogen receptor 3.262e-08 0.67
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 3.348e-08 0.73
GRM7_RAT Grm7 Metabotropic glutamate receptor 7 3.589e-08 0.30
DPP4_PIG DPP4 Dipeptidyl peptidase 4 4.031e-08 0.56
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 5.31e-08 0.35
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 8.88e-08 0.31
AHR_HUMAN AHR Aryl hydrocarbon receptor 9.735e-08 0.38
ANDR_HUMAN AR Androgen receptor 1.273e-07 0.67
A3KMY8_BOVIN GUSB Beta-glucuronidase 1.498e-07 0.36
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.848e-07 0.33
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 3.162e-07 0.42
PPO2_AGABI PPO2 Polyphenol oxidase 2 3.854e-07 0.43
ALDR_PIG AKR1B1 Aldo-keto reductase family 1 member B1 4.064e-07 0.40
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 4.088e-07 0.45
GPR35_HUMAN GPR35 G-protein coupled receptor 35 6.303e-07 0.71
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 7.646e-07 0.40
ACES_HUMAN ACHE Acetylcholinesterase 9.129e-07 0.67
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 9.875e-07 0.33
CHLE_HORSE BCHE Cholinesterase 1e-06 0.38
CLK1_MOUSE Clk1 Dual specificity protein kinase CLK1 1.347e-06 0.31
PERM_HUMAN MPO Myeloperoxidase 1.613e-06 0.67
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 1.992e-06 0.42
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.697e-06 0.71
AA1R_RAT Adora1 Adenosine receptor A1 3.768e-06 0.71
O40947_HHV8 ORF 73 4.307e-06 0.38
HCK_HUMAN HCK Tyrosine-protein kinase HCK 4.638e-06 0.36
TYRO_HUMAN TYR Tyrosinase 5.096e-06 0.56
ULA1_HUMAN NAE1 NEDD8-activating enzyme E1 regulatory subunit 6.085e-06 0.47
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 6.257e-06 0.34
CAH13_MOUSE Ca13 Carbonic anhydrase 13 6.67e-06 0.43
IL5_MOUSE Il5 Interleukin-5 7.451e-06 0.30
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 8.673e-06 0.34

Ononin

IL2_HUMAN IL2 Interleukin-2 8.123e-63 1.00
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 2.817e-168 0.57
ALDH2_HUMAN ALDH2 Aldehyde dehydrogenase, mitochondrial 4.596e-149 0.84
CD22_HUMAN CD22 B-cell receptor CD22 1.932e-95 0.34
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 1.778e-93 0.47
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 2.699e-68 0.50
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 8.378e-56 0.47
FAS_CHICK FASN Fatty acid synthase 2.703e-52 0.42
GGTA1_PIG GGTA1 N-acetyllactosaminide alpha-1,3-galactosyltransferase 6.968e-52 0.41
B4EH87_BURCJ Lectin 6.635e-48 0.57
S28A3_HUMAN SLC28A3 Solute carrier family 28 member 3 3.859e-43 0.34
SC5A1_RAT Slc5a1 Sodium/glucose cotransporter 1 1.384e-41 0.36
GOB1_BRUMA Trehalose-phosphatase 6.678e-41 0.32
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 8.198e-41 0.40
SC5A2_RAT Slc5a2 Sodium/glucose cotransporter 2 5.036e-40 0.36
RASN_HUMAN NRAS GTPase NRas 5.748e-39 0.31
PDIA1_HUMAN P4HB Protein disulfide-isomerase 9.559e-34 0.44
LEG9_HUMAN LGALS9 Galectin-9 4.071e-33 0.34
TYRO_HUMAN TYR Tyrosinase 3.514e-30 0.44
G3PC_LEIME GAPC Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 9.036e-30 0.29
O96394_LEIAM Arginase 6.156e-29 0.43
CD22_MOUSE Cd22 B-cell receptor CD22 1.221e-28 0.32
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 2.664e-27 0.84
SC5AB_HUMAN SLC5A11 Sodium/myo-inositol cotransporter 2 2.669e-26 0.32
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 2.495e-25 0.84
LEG3_HUMAN LGALS3 Galectin-3 4.558e-25 0.34
SC5A4_HUMAN SLC5A4 Solute carrier family 5 member 4 6.686e-25 0.47
LEG7_HUMAN LGALS7; LGALS7B Galectin-7 6.089e-24 0.32
ADK_TOXGO AK Adenosine kinase 8.431e-22 0.36
G3P_HUMAN GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1.695e-21 0.30
SC5A2_MOUSE Slc5a2 Sodium/glucose cotransporter 2 3.565e-20 0.31
S28A2_HUMAN SLC28A2 Sodium/nucleoside cotransporter 2 5.588e-19 0.29
B4GT1_HUMAN B4GALT1 Beta-1,4-galactosyltransferase 1 6.741e-19 0.30
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 1.422e-18 0.44
FGF1_HUMAN FGF1 Fibroblast growth factor 1 1.11e-16 0.30
FGF2_HUMAN FGF2 Fibroblast growth factor 2 9.703e-14 0.30
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 4.331e-13 0.51
GDE_RABIT AGL Glycogen debranching enzyme 6.108e-13 0.28
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 8.662e-13 0.32
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 4.628e-12 0.29
ADOK_MYCTO adoK Adenosine kinase 4.63e-12 0.41
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 9.7e-12 0.29
LEG1_HUMAN LGALS1 Galectin-1 2.11e-11 0.33
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 2.353e-11 0.44
IL5_MOUSE Il5 Interleukin-5 3.667e-11 0.62
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 1.098e-10 0.34
KLK7_HUMAN KLK7 Kallikrein-7 1.138e-10 0.50
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 2.013e-10 0.36
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 4.233e-10 0.30
DPO1_THEAQ polA DNA polymerase I, thermostable 5.524e-10 0.49
CAH12_HUMAN CA12 Carbonic anhydrase 12 5.942e-10 0.57
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 1.555e-09 0.43
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 4.289e-09 0.36
ACES_RAT Ache Acetylcholinesterase 5.36e-09 0.38
IL6_HUMAN IL6 Interleukin-6 8.709e-09 0.35
AA1R_CHICK ADORA1 Adenosine receptor A1 9.262e-09 0.35
SQHC_ALIAD shc Squalene--hopene cyclase 1.457e-08 0.31
LYAG_RAT Gaa Lysosomal alpha-glucosidase 2.812e-08 0.31
CAH7_HUMAN CA7 Carbonic anhydrase 7 3.055e-08 0.49
CAH9_HUMAN CA9 Carbonic anhydrase 9 3.435e-08 0.57
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 4.306e-08 0.43
CAH13_HUMAN CA13 Carbonic anhydrase 13 7.499e-08 0.49
EGLN1_RAT Egln1 Egl nine homolog 1 1.274e-07 0.29
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.425e-07 0.37
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 1.533e-07 0.57
CAH4_HUMAN CA4 Carbonic anhydrase 4 3.33e-07 0.44
CAH15_MOUSE Ca15 Carbonic anhydrase 15 3.47e-07 0.31
SMO_MOUSE Smo Smoothened homolog 3.756e-07 0.38
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 4.177e-07 0.29
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 9.588e-07 0.33
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 2.288e-06 0.31
PPO2_AGABI PPO2 Polyphenol oxidase 2 4.438e-06 0.39
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 5.031e-06 0.43
CAH1_HUMAN CA1 Carbonic anhydrase 1 5.134e-06 0.57
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 5.706e-06 0.30
DNPH1_RAT Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 8.208e-06 0.29

Luteolin-7-O-glucoside

IL2_HUMAN IL2 Interleukin-2 7.799e-42 1.00
TNFA_HUMAN TNF Tumor necrosis factor 7.785e-05 1.00
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 4.997e-143 0.48
FAS_CHICK FASN Fatty acid synthase 2.903e-77 0.62
TOP1_RAT Top1 DNA topoisomerase 1 1.978e-69 0.56
CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 5.266e-69 0.35
O96394_LEIAM Arginase 5.175e-59 0.63
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 1.455e-57 0.39
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 1.081e-55 0.41
SC5A1_RAT Slc5a1 Sodium/glucose cotransporter 1 9.47e-52 0.39
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 3.062e-50 0.33
OPRD_PIG OPRD1 Delta-type opioid receptor 3.639e-49 0.39
S28A3_HUMAN SLC28A3 Solute carrier family 28 member 3 8.334e-48 0.38
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 3.588e-47 0.57
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 8.737e-47 0.63
AK1CL_MOUSE Akr1c21 Aldo-keto reductase family 1 member C21 1.175e-46 0.37
DDL_HELPH ddl D-alanine--D-alanine ligase 1.175e-46 0.37
ARGI1_RAT Arg1 Arginase-1 1.955e-44 0.56
PDIA1_HUMAN P4HB Protein disulfide-isomerase 2.551e-44 0.63
TYRO_HUMAN TYR Tyrosinase 4.607e-42 0.47
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 9.551e-42 0.39
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 2.686e-41 0.41
SC5A2_RAT Slc5a2 Sodium/glucose cotransporter 2 3.434e-41 0.39
GGTA1_PIG GGTA1 N-acetyllactosaminide alpha-1,3-galactosyltransferase 5.512e-41 0.33
B4EH87_BURCJ Lectin 1.231e-40 0.48
GOB1_BRUMA Trehalose-phosphatase 1.007e-38 0.31
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 5.066e-38 0.38
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 8.869e-37 0.56
FPS_FUJSV V-FPS Tyrosine-protein kinase transforming protein Fps 1.377e-35 0.28
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 8.283e-33 0.58
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 9.108e-33 0.41
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 3.92e-30 0.56
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 5.863e-30 0.37
BGLR_RAT Gusb Beta-glucuronidase 3.085e-27 0.44
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 3.093e-25 0.56
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 5.202e-25 0.45
CBS_HUMAN CBS Cystathionine beta-synthase 2.294e-24 0.40
SC5AB_HUMAN SLC5A11 Sodium/myo-inositol cotransporter 2 1.444e-23 0.29
VE6_HPV16 E6 Protein E6 6.377e-23 0.28
SYN1_BOVIN SYN1 Synapsin-1 6.654e-21 0.33
KITH_VZVD TK Thymidine kinase 1.054e-20 0.32
R1AB_SARS rep Replicase polyprotein 1ab 2.373e-20 0.39
PLGF_HUMAN PGF Placenta growth factor 2.423e-20 0.39
TOP1_MOUSE Top1 DNA topoisomerase 1 3.167e-20 0.29
AMY1A_HUMAN AMY1A Alpha-amylase 1 6.051e-20 0.38
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 1.035e-18 0.32
B4GT1_HUMAN B4GALT1 Beta-1,4-galactosyltransferase 1 6.229e-18 0.28
NOX4_HUMAN NOX4 NADPH oxidase 4 6.402e-18 0.63
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 9.662e-18 0.44
FGF1_HUMAN FGF1 Fibroblast growth factor 1 1.825e-17 0.31
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 1.11e-16 0.51
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 1.11e-16 0.39
MALX3_YEAST IMA1 Oligo-1,6-glucosidase IMA1 8.882e-16 0.30
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 1.11e-15 0.51
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 2.887e-15 0.34
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 7.105e-15 0.48
RASH_HUMAN HRAS GTPase HRas 1.199e-14 0.39
SC5A4_HUMAN SLC5A4 Solute carrier family 5 member 4 2.109e-14 0.39
FGF2_HUMAN FGF2 Fibroblast growth factor 2 3.797e-14 0.31
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 6.328e-14 0.66
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 2.561e-13 0.41
GDE_RABIT AGL Glycogen debranching enzyme 6.108e-13 0.28
LGUL_HUMAN GLO1 Lactoylglutathione lyase 1.138e-12 0.56
MDH_THETH mdh Malate dehydrogenase 1.133e-11 0.37
PERL_BOVIN LPO Lactoperoxidase 1.133e-11 0.37
NANH_CLOPF nanH Sialidase 1.899e-11 0.56
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 2.045e-11 0.46
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 4.02e-11 0.63
CAH4_HUMAN CA4 Carbonic anhydrase 4 4.392e-11 0.63
CAH7_HUMAN CA7 Carbonic anhydrase 7 5.312e-11 0.63
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 5.64e-11 0.45
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 6.106e-11 0.37
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 7.689e-11 0.37
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 1.002e-10 0.34
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 1.333e-10 0.56
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 2.048e-10 0.41
IL5_MOUSE Il5 Interleukin-5 2.538e-10 0.57
CAH12_HUMAN CA12 Carbonic anhydrase 12 3.229e-10 0.63
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 3.287e-10 0.37
DPO1_THEAQ polA DNA polymerase I, thermostable 3.359e-10 0.40
Q7ZJM1_9HIV1 pol Integrase 4.038e-10 0.45
PPO2_AGABI PPO2 Polyphenol oxidase 2 5.089e-10 0.37
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 5.288e-10 0.63
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 8.528e-10 0.45
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.061e-09 0.44
CD22_MOUSE Cd22 B-cell receptor CD22 4.372e-09 0.28
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 4.395e-09 0.56
ACES_RAT Ache Acetylcholinesterase 4.729e-09 0.31
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 1.17e-08 0.38
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.197e-08 0.56
CP2C8_HUMAN CYP2C8 Cytochrome P450 2C8 1.518e-08 0.37
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 1.716e-08 0.48
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 4.83e-08 0.56
CALM1_HUMAN CALM1 Calmodulin-1 5.192e-08 0.28
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 1.18e-07 0.37
CAH13_HUMAN CA13 Carbonic anhydrase 13 1.254e-07 0.42
IL6_HUMAN IL6 Interleukin-6 1.721e-07 0.29
CAH9_HUMAN CA9 Carbonic anhydrase 9 1.755e-07 0.48
ALDR_PIG AKR1B1 Aldo-keto reductase family 1 member B1 1.938e-07 0.52
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 2.329e-07 0.63
TTHY_HUMAN TTR Transthyretin 3.121e-07 0.56
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 3.404e-07 0.34
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 3.48e-07 0.37
B4URF0_I33A0 Neuraminidase 4.234e-07 0.47
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 5.464e-07 0.28
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 8.317e-07 0.56
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 9.89e-07 0.56
TERT_HUMAN TERT Telomerase reverse transcriptase 1.05e-06 0.40
ALDH2_HUMAN ALDH2 Aldehyde dehydrogenase, mitochondrial 2.103e-06 0.51
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 2.682e-06 0.44
CAH3_HUMAN CA3 Carbonic anhydrase 3 3.75e-06 0.37
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 4.957e-06 0.28
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 4.965e-06 0.37
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 8.575e-06 0.75
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 8.93e-06 0.56
TNNC1_HUMAN TNNC1 Troponin C, slow skeletal and cardiac muscles 9.367e-06 0.37
TNNI3_HUMAN TNNI3 Troponin I, cardiac muscle 9.367e-06 0.37
TNNT2_HUMAN TNNT2 Troponin T, cardiac muscle 9.367e-06 0.37
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 9.38e-06 0.56

Dihydromyricetin

MMP12_HUMAN MMP12 Macrophage metalloelastase 0.0003932 1.00
MMP13_HUMAN MMP13 Collagenase 3 0.8636 1.00
G6PD_YEAST ZWF1 Glucose-6-phosphate 1-dehydrogenase 9.274e-83 0.44
Q8IDJ8_PLAF7 Lysine--tRNA ligase 2.451e-57 0.28
FUT4_HUMAN FUT4 Alpha-(1,3)-fucosyltransferase 4 1.855e-55 0.44
Q8I2S7_PLAF7 3-oxoacyl-[acyl-carrier-protein] reductase 1.855e-55 0.44
O96394_LEIAM Arginase 2.135e-52 0.48
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 5.24e-49 0.44
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 1.162e-48 0.44
6PGD_HUMAN PGD 6-phosphogluconate dehydrogenase, decarboxylating 4.576e-43 0.44
FPS_FUJSV V-FPS Tyrosine-protein kinase transforming protein Fps 3.568e-41 0.33
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 8.932e-41 0.38
SIAT6_HUMAN ST3GAL3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 1.489e-35 0.44
T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 1.508e-31 0.31
PGAM1_HUMAN PGAM1 Phosphoglycerate mutase 1 1.845e-27 0.44
VE6_HPV16 E6 Protein E6 1.792e-26 0.33
FUT7_HUMAN FUT7 Alpha-(1,3)-fucosyltransferase 7 7.012e-20 0.44
ERG1_RAT Sqle Squalene monooxygenase 2.569e-17 0.44
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 3.05e-17 0.53
CBS_HUMAN CBS Cystathionine beta-synthase 4.464e-17 0.47
KLK2_HUMAN KLK2 Kallikrein-2 1.11e-16 0.42
PLGF_HUMAN PGF Placenta growth factor 2.665e-15 0.29
REST_BORBU resT Telomere resolvase ResT 3.852e-14 0.35
MTSI_SPISQ sssIM CPG DNA methylase 9.137e-14 0.44
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 3.052e-11 0.44
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 3.4e-08 0.49
CAH3_HUMAN CA3 Carbonic anhydrase 3 1.101e-07 0.49
CAH15_MOUSE Ca15 Carbonic anhydrase 15 4.94e-07 0.49

Cyclic-adenosine-monophosphate-(cAMP)

OXGR1_RAT Oxgr1 2-oxoglutarate receptor 1 2.7e-204 0.53
SAHH_HUMAN AHCY Adenosylhomocysteinase 5.516e-167 0.55
AA1R_RAT Adora1 Adenosine receptor A1 8.903e-162 0.53
SAHH_RAT Ahcy Adenosylhomocysteinase 5.374e-143 0.53
C3SIU2_ECOLX metJ Met repressor 3.018e-136 0.44
DOT1L_HUMAN DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 9.694e-121 0.46
AA3R_RAT Adora3 Adenosine receptor A3 3.096e-119 0.53
DNPH1_HUMAN DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 1.167e-114 0.35
DNPH1_RAT Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 1.272e-112 0.35
AA2AR_RAT Adora2a Adenosine receptor A2a 4.222e-111 0.53
MTAP_MOUSE Mtap S-methyl-5'-thioadenosine phosphorylase 4.282e-109 0.48
SAHH_MOUSE Ahcy Adenosylhomocysteinase 2.872e-107 0.50
Q9HX69_PSEAE rocR RocR 3.322e-107 0.66
DCAM_HUMAN AMD1 S-adenosylmethionine decarboxylase proenzyme 1.618e-106 0.48
ADK_TOXGO AK Adenosine kinase 2.917e-106 0.52
AA1R_CHICK ADORA1 Adenosine receptor A1 4.686e-102 0.47
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 4.749e-98 0.36
MBTA_MYCTU mbtA Salicyl-AMP ligase / salicyl-S-ArCP synthetase 1.296e-96 0.44
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 3.771e-96 0.46
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 1.368e-89 0.50
P2RY1_RAT P2ry1 P2Y purinoceptor 1 2.779e-86 0.49
ADCY5_HUMAN ADCY5 Adenylate cyclase type 5 1.185e-83 0.37
Q8TA74_HEMPU Ryanodine receptor 1.288e-83 0.52
SPEE_HUMAN SRM Spermidine synthase 6.765e-80 0.41
SYQ_HUMAN QARS1 Glutamine--tRNA ligase 6.601e-77 0.43
I6YFP0_MYCTU birA Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase) 1.575e-75 0.35
KAD2_RAT Ak2 Adenylate kinase 2, mitochondrial 1.978e-74 0.48
AA1R_CAVPO ADORA1 Adenosine receptor A1 2.22e-73 0.52
Q99MI5_RAT LOC100912604 Spermidine synthase 7.15e-72 0.41
ASNS_HUMAN ASNS Asparagine synthetase [glutamine-hydrolyzing] 5.942e-70 0.39
KAD3_RAT Ak3 GTP:AMP phosphotransferase AK3, mitochondrial 1.698e-69 0.48
KTHY_HUMAN DTYMK Thymidylate kinase 1.871e-69 0.41
IMDH2_MOUSE Impdh2 Inosine-5'-monophosphate dehydrogenase 2 3.682e-69 0.39
SAHH_PLAF7 Adenosylhomocysteinase 1.299e-67 0.47
SNAT_SHEEP AANAT Serotonin N-acetyltransferase 1.421e-66 0.30
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 5.287e-65 0.49
PQSA_PSEAE pqsA Anthranilate--CoA ligase 1.292e-64 0.41
AA3R_HUMAN ADORA3 Adenosine receptor A3 9.628e-63 0.52
DHE3_BOVIN GLUD1 Glutamate dehydrogenase 1, mitochondrial 1.185e-62 0.40
PANE_ECOLI panE 2-dehydropantoate 2-reductase 1.503e-62 0.39
IMDH1_HUMAN IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 4.151e-62 0.39
SPSY_HUMAN SMS Spermine synthase 4.532e-62 0.41
SYRC_HUMAN RARS1 Arginine--tRNA ligase, cytoplasmic 2.269e-61 0.40
P2Y11_HUMAN P2RY11 P2Y purinoceptor 11 3.743e-61 0.47
RNAS1_HUMAN RNASE1 Ribonuclease pancreatic 1.776e-59 0.38
RNAS2_HUMAN RNASE2 Non-secretory ribonuclease 1.776e-59 0.38
NADK_HUMAN NADK NAD kinase 2.075e-59 0.42
RN5A_MOUSE Rnasel 2-5A-dependent ribonuclease 2.937e-59 0.43
P2RY4_RAT P2ry4 P2Y purinoceptor 4 3.206e-59 0.49
HSP7C_BOVIN HSPA8 Heat shock cognate 71 kDa protein 6.014e-59 0.47
WALK_STAAU walK Sensor protein kinase WalK 6.014e-59 0.47
ENPL_PIG HSP90B1 Endoplasmin 7.747e-59 0.47
PARG_BOVIN PARG Poly(ADP-ribose) glycohydrolase 2.288e-58 0.43
KMT5C_HUMAN KMT5C Histone-lysine N-methyltransferase KMT5C 4.175e-58 0.46
SETB1_HUMAN SETDB1 Histone-lysine N-methyltransferase SETDB1 4.175e-58 0.46
MACD1_HUMAN MACROD1 ADP-ribose glycohydrolase MACROD1 2.742e-57 0.46
MACD2_HUMAN MACROD2 ADP-ribose glycohydrolase MACROD2 2.742e-57 0.46
MSHC_MYCTU mshC L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 1.164e-56 0.45
SYS_ECOLI serS Serine--tRNA ligase 6.599e-56 0.45
ENPP1_RAT Enpp1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 2.189e-55 0.46
RN5A_HUMAN RNASEL 2-5A-dependent ribonuclease 1.851e-54 0.43
SYD_ECOLI aspS Aspartate--tRNA ligase 1.851e-54 0.43
METK2_RAT Mat2a S-adenosylmethionine synthase isoform type-2 1.425e-52 0.42
Q9HWG3_PSEAE pchD Pyochelin biosynthesis protein PchD 1.67e-51 0.41
SYY_ECOLI tyrS Tyrosine--tRNA ligase 3.751e-51 0.41
SETD2_HUMAN SETD2 Histone-lysine N-methyltransferase SETD2 1.471e-50 0.40
AA1R_HUMAN ADORA1 Adenosine receptor A1 2.083e-50 0.52
P2RX5_RAT P2rx5 P2X purinoceptor 5 2.355e-50 0.49
P2RX6_RAT P2rx6 P2X purinoceptor 6 2.355e-50 0.49
HARS1_HUMAN HARS1 Histidine--tRNA ligase, cytoplasmic 6.101e-50 0.40
METK1_RAT Mat1a S-adenosylmethionine synthase isoform type-1 2.604e-49 0.46
MENB_MYCTU menB 1,4-dihydroxy-2-naphthoyl-CoA synthase 2.484e-47 0.30
NADK1_LISMF nadK1 NAD kinase 1 3.737e-47 0.38
NADK_STAAC nadK NAD kinase 3.737e-47 0.38
BIP_HUMAN HSPA5 Endoplasmic reticulum chaperone BiP 8.155e-47 0.47
AA3R_RABIT ADORA3 Adenosine receptor A3 1.151e-45 0.30
SYI_ECOLI ileS Isoleucine--tRNA ligase 1.373e-45 0.41
BIRA_ECOLI birA Bifunctional ligase/repressor BirA 9.364e-45 0.36
AA1R_RABIT ADORA1 Adenosine receptor A1 5.168e-44 0.30
Q70E71_9ENTE aac(6')-Ii Aminoglycoside N(6')-acetyltransferase 2.684e-43 0.31
HSP7C_HUMAN HSPA8 Heat shock cognate 71 kDa protein 4.096e-42 0.47
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 2.252e-40 0.45
UBA7_HUMAN UBA7 Ubiquitin-like modifier-activating enzyme 7 1.271e-39 0.31
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 6.821e-39 0.49
ADK_HUMAN ADK Adenosine kinase 1.488e-38 0.52
ENTP1_BOVIN ENTPD1 Ectonucleoside triphosphate diphosphohydrolase 1 2.435e-37 0.30
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 6.857e-37 0.52
ANM7_HUMAN PRMT7 Protein arginine N-methyltransferase 7 8.861e-35 0.43
SYL_ECOLI leuS Leucine--tRNA ligase 1.78e-34 0.43
P2RX4_RAT P2rx4 P2X purinoceptor 4 1.045e-33 0.49
ADA_MOUSE Ada Adenosine deaminase 3.128e-33 0.41
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 1.005e-32 0.40
G3P_HUMAN GAPDH Glyceraldehyde-3-phosphate dehydrogenase 9.641e-32 0.42
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 7.584e-31 0.39
A0A0E7NXW5_STAAU birA Bifunctional ligase/repressor BirA 3.263e-30 0.36
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 7.35e-30 0.49
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 1.223e-29 0.41
SUV91_HUMAN SUV39H1 Histone-lysine N-methyltransferase SUV39H1 2.824e-29 0.46
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 4.095e-29 0.39
ADCY5_RAT Adcy5 Adenylate cyclase type 5 7.224e-28 0.49
PARG_HUMAN PARG Poly(ADP-ribose) glycohydrolase 5.665e-27 0.43
PANC_MYCTU panC Pantothenate synthetase 1.172e-26 0.43
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 1.326e-26 0.31
S29A1_RAT Slc29a1 Equilibrative nucleoside transporter 1 2.669e-26 0.32
NMT_YEAST NMT1 Glycylpeptide N-tetradecanoyltransferase 2.929e-26 0.32
NNMT_HUMAN NNMT Nicotinamide N-methyltransferase 3.399e-26 0.36
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 5.599e-26 0.46
UBA6_HUMAN UBA6 Ubiquitin-like modifier-activating enzyme 6 1.737e-25 0.31
BPL1_HUMAN HLCS Biotin--protein ligase 2.928e-25 0.36
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 4.411e-25 0.40
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 8.1e-25 0.46
SYMC_HUMAN MARS1 Methionine--tRNA ligase, cytoplasmic 8.944e-25 0.42
AMPD1_RABIT AMPD1 AMP deaminase 1 1.685e-24 0.30
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 2.696e-24 0.46
ADCY2_RAT Adcy2 Adenylate cyclase type 2 3.121e-24 0.38
ADA_BOVIN ADA Adenosine deaminase 3.761e-24 0.38
KITH_RAT Tk1 Thymidine kinase, cytosolic 4.395e-23 0.37
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 6.311e-23 0.46
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1.151e-22 0.50
DCAM_RAT Amd1 S-adenosylmethionine decarboxylase proenzyme 3.694e-20 0.48
IUNH_CRIFA IUNH Inosine-uridine preferring nucleoside hydrolase 3.055e-19 0.37
O15727_TRYBB Inosine-adenosine-guanosine-nucleoside hydrolase 3.055e-19 0.37
E1BN64_BOVIN PDE3B Phosphodiesterase 6.81e-19 0.66
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 8.47e-19 0.50
P96884_MYCTO birA BirA bifunctional protein 2.299e-18 0.35
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 3.005e-18 0.46
EZH1_HUMAN EZH1 Histone-lysine N-methyltransferase EZH1 4.732e-18 0.46
Q4VQ11_PIG Adenosine receptor A1 8.026e-18 0.36
GPR17_HUMAN GPR17 Uracil nucleotide/cysteinyl leukotriene receptor 1.209e-17 0.36
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 1.4e-17 0.50
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 1.11e-16 0.49
P2RX1_RAT P2rx1 P2X purinoceptor 1 2.22e-16 0.32
SYTC_HUMAN TARS1 Threonine--tRNA ligase 1, cytoplasmic 6.661e-16 0.42
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.22e-15 0.41
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 4.663e-15 0.49
IF4E_RABIT EIF4E Eukaryotic translation initiation factor 4E 1.399e-14 0.28
5NTD_HUMAN NT5E 5'-nucleotidase 2.398e-14 0.45
KAPCA_HUMAN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 2.72e-14 0.45
ADH1A_HUMAN ADH1A Alcohol dehydrogenase 1A 2.787e-14 0.40
AA2AR_MOUSE Adora2a Adenosine receptor A2a 1.704e-13 0.29
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 2.862e-13 0.29
P2RX2_RAT P2rx2 P2X purinoceptor 2 4.057e-13 0.49
PUR6_CHICK AIRC Multifunctional protein ADE2 4.751e-13 0.28
KMT2A_HUMAN KMT2A Histone-lysine N-methyltransferase 2A 1.042e-12 0.46
HPPK_ECOLI folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 1.261e-12 0.37
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 6.446e-12 0.46
AA1R_BOVIN ADORA1 Adenosine receptor A1 9.197e-12 0.47
M9TGV3_MYCTX inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 2.955e-11 0.36
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 8.843e-11 0.43
INMT_HUMAN INMT Indolethylamine N-methyltransferase 1.703e-10 0.46
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 2.521e-10 0.35
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 2.659e-10 0.30
RAB7A_HUMAN RAB7A Ras-related protein Rab-7a 6.359e-10 0.31
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 1.37e-09 0.30
5NTD_RAT Nt5e 5'-nucleotidase 1.498e-09 0.47
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 1.812e-09 0.49
O39930_9HEPC NS5b RNA-directed RNA polymerase 2.368e-09 0.48
ENPL_CANLF HSP90B1 Endoplasmin 1.174e-08 0.49
P2Y12_RAT P2ry12 P2Y purinoceptor 12 1.643e-08 0.49
Q9Y0I0_9TRYP AT1 Adenosine transporter 1 2.322e-08 0.38
SYT_YERPE thrS Threonine--tRNA ligase 2.6e-08 0.42
EZH2_HUMAN EZH2 Histone-lysine N-methyltransferase EZH2 4.302e-08 0.46
AA1R_MOUSE Adora1 Adenosine receptor A1 8.157e-08 0.30
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 9.381e-08 0.33
CDD_MOUSE Cda Cytidine deaminase 2.567e-07 0.30
ADA_HUMAN ADA Adenosine deaminase 3.539e-07 0.35
RPGF3_HUMAN RAPGEF3 Rap guanine nucleotide exchange factor 3 6.915e-07 0.47
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 8.945e-07 0.46
SMYD2_HUMAN SMYD2 N-lysine methyltransferase SMYD2 9.513e-07 0.46
LUCI_AQULA Luciferin 4-monooxygenase 9.875e-07 0.33
DPOLB_HUMAN POLB DNA polymerase beta 1.329e-06 0.39
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 1.33e-06 0.33
CLAT_HUMAN CHAT Choline O-acetyltransferase 1.633e-06 0.34
G3PC_LEIME GAPC Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 1.944e-06 0.28
Q56950_YERPE ybtE Salicyl-AMP ligase YbtE 2.706e-06 0.41
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 7.771e-06 0.52

Gentiopicroside

FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 6.09e-118 0.38
LEG4_HUMAN LGALS4 Galectin-4 6.96e-63 0.35
LEG8_HUMAN LGALS8 Galectin-8 6.96e-63 0.35
CXB2_HUMAN GJB2 Gap junction beta-2 protein 9.519e-41 0.32
GGTA1_PIG GGTA1 N-acetyllactosaminide alpha-1,3-galactosyltransferase 1.972e-40 0.32
FGF1_HUMAN FGF1 Fibroblast growth factor 1 9.71e-38 0.37
FAS_CHICK FASN Fatty acid synthase 3.875e-36 0.29
S28A3_HUMAN SLC28A3 Solute carrier family 28 member 3 6.705e-36 0.28
B4EH87_BURCJ Lectin 3.799e-34 0.34
MALX3_YEAST IMA1 Oligo-1,6-glucosidase IMA1 2.225e-30 0.30
FGF2_HUMAN FGF2 Fibroblast growth factor 2 2.983e-24 0.37
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 1.944e-23 0.30
ADA_MOUSE Ada Adenosine deaminase 2.847e-23 0.29
LEG3_HUMAN LGALS3 Galectin-3 1.296e-22 0.36
TYRO_HUMAN TYR Tyrosinase 2.056e-21 0.32
IL2_HUMAN IL2 Interleukin-2 1.568e-20 0.30
AMYP_HUMAN AMY2A Pancreatic alpha-amylase 4.22e-20 0.32
CDD_MOUSE Cda Cytidine deaminase 1.683e-19 0.29
B4GT1_HUMAN B4GALT1 Beta-1,4-galactosyltransferase 1 1.372e-18 0.29
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 1.065e-17 0.37
CDD_HUMAN CDA Cytidine deaminase 3.649e-17 0.29
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 5.321e-17 0.32
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 2.22e-15 0.29
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 2.787e-14 0.32
LEG9_HUMAN LGALS9 Galectin-9 1.24e-13 0.36
GDE_RABIT AGL Glycogen debranching enzyme 1.549e-13 0.30
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 7.058e-11 0.32
SC5A1_RAT Slc5a1 Sodium/glucose cotransporter 1 3.238e-10 0.30
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 5.732e-10 0.29
PDIA1_HUMAN P4HB Protein disulfide-isomerase 9.65e-10 0.31
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 2.791e-09 0.29
O96394_LEIAM Arginase 5.825e-09 0.30
SC5A4_HUMAN SLC5A4 Solute carrier family 5 member 4 1.148e-08 0.30
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.946e-08 0.35
SC5A2_RAT Slc5a2 Sodium/glucose cotransporter 2 5.39e-08 0.30
CAH14_HUMAN CA14 Carbonic anhydrase 14 7.936e-08 0.31
LEG7_HUMAN LGALS7; LGALS7B Galectin-7 1.138e-07 0.28
CAH9_HUMAN CA9 Carbonic anhydrase 9 1.171e-07 0.35
CAH13_HUMAN CA13 Carbonic anhydrase 13 1.548e-06 0.32
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 6.184e-06 0.32
IL5_MOUSE Il5 Interleukin-5 7.965e-06 0.30

Citric-acid

S13A5_HUMAN SLC13A5 Solute carrier family 13 member 5 1.152e-96 0.44
ACLY_RAT Acly ATP-citrate synthase 2.265e-80 0.46
S13A2_HUMAN SLC13A2 Solute carrier family 13 member 2 5.13e-43 0.34
S13A3_HUMAN SLC13A3 Solute carrier family 13 member 3 5.13e-43 0.34
S13A5_MOUSE Slc13a5 Solute carrier family 13 member 5 5.13e-43 0.34
S13A5_RAT Slc13a5 Solute carrier family 13 member 5 5.13e-43 0.34
EAA3_RAT Slc1a1 Excitatory amino acid transporter 3 8.37e-41 0.32
GBRT_HUMAN GABRQ Gamma-aminobutyric acid receptor subunit theta 1.947e-38 0.30
S6A13_RAT Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.947e-38 0.30
ACLY_HUMAN ACLY ATP-citrate synthase 1.77e-29 0.46
GABT_PIG ABAT 4-aminobutyrate aminotransferase, mitochondrial 8.933e-22 0.35
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 5.551e-16 0.30
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.804e-12 0.37
Q6RY99_RAT Tetraspanin 8.327e-12 0.32
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 1.936e-10 0.30
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 1.91e-07 0.30
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 7.045e-07 0.29
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.87e-06 0.33
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 2.064e-06 0.30
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 2.561e-06 0.31
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 3.285e-06 0.30
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 5.703e-06 0.37

Aloin

SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 6.285e-78 0.39
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 2.325e-76 0.34
AL1A7_RAT Aldh1a7 Aldehyde dehydrogenase, cytosolic 1 1.898e-75 0.50
ALDH2_RAT Aldh2 Aldehyde dehydrogenase, mitochondrial 1.414e-62 0.50
Q9BEG3_BOVIN 5-lipoxygenase 2.802e-59 0.42
CDD_MOUSE Cda Cytidine deaminase 9.069e-54 0.33
LOX12_MOUSE Alox12 Arachidonate 12-lipoxygenase, 12S-type 1.525e-46 0.32
TOP1_MOUSE Top1 DNA topoisomerase 1 2.116e-40 0.31
RASN_HUMAN NRAS GTPase NRas 3.17e-38 0.30
S28A3_HUMAN SLC28A3 Solute carrier family 28 member 3 6.694e-38 0.30
CDD_HUMAN CDA Cytidine deaminase 4.924e-36 0.33
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 6.252e-36 0.34
FAS_CHICK FASN Fatty acid synthase 6.705e-36 0.28
B4EH87_BURCJ Lectin 4.423e-31 0.31
MALX3_YEAST IMA1 Oligo-1,6-glucosidase IMA1 3.303e-30 0.30
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 5.891e-27 0.34
ADA_MOUSE Ada Adenosine deaminase 1.481e-26 0.33
SC5AB_HUMAN SLC5A11 Sodium/myo-inositol cotransporter 2 5.889e-23 0.28
TOP1_HUMAN TOP1 DNA topoisomerase 1 2.074e-21 0.36
SC5A2_RAT Slc5a2 Sodium/glucose cotransporter 2 2.998e-15 0.31
UMPS_HUMAN UMPS Uridine 5'-monophosphate synthase 4.441e-15 0.29
TYRO_HUMAN TYR Tyrosinase 7.883e-15 0.31
AGRA_STAAU agrA Accessory gene regulator protein A 1.599e-14 0.36
RASH_HUMAN HRAS GTPase HRas 3.603e-13 0.36
CAH12_HUMAN CA12 Carbonic anhydrase 12 6.104e-13 0.36
SC5A4_HUMAN SLC5A4 Solute carrier family 5 member 4 9.895e-13 0.31
CAH14_HUMAN CA14 Carbonic anhydrase 14 4.064e-12 0.36
PYRF_METTH pyrF Orotidine 5'-phosphate decarboxylase 9.7e-12 0.29
CAH9_HUMAN CA9 Carbonic anhydrase 9 1.334e-11 0.36
SC5A1_RAT Slc5a1 Sodium/glucose cotransporter 1 9.374e-11 0.31
IL2_HUMAN IL2 Interleukin-2 1.176e-10 0.30
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 6.538e-10 0.29
CAH1_HUMAN CA1 Carbonic anhydrase 1 8.829e-10 0.36
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 3.152e-09 0.29
IL6_HUMAN IL6 Interleukin-6 3.482e-09 0.37
G6PT1_HUMAN SLC37A4 Glucose-6-phosphate exchanger SLC37A4 5.367e-09 0.30
O96394_LEIAM Arginase 6.365e-09 0.30
FGF1_HUMAN FGF1 Fibroblast growth factor 1 1.153e-08 0.29
TNNC1_HUMAN TNNC1 Troponin C, slow skeletal and cardiac muscles 3.642e-08 0.54
TNNI3_HUMAN TNNI3 Troponin I, cardiac muscle 3.642e-08 0.54
TNNT2_HUMAN TNNT2 Troponin T, cardiac muscle 3.642e-08 0.54
CAH2_HUMAN CA2 Carbonic anhydrase 2 3.855e-08 0.36
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 1.017e-07 0.30
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 1.849e-07 0.29
FGF2_HUMAN FGF2 Fibroblast growth factor 2 4.396e-07 0.29
CAH13_HUMAN CA13 Carbonic anhydrase 13 6.368e-07 0.35
PDIA1_HUMAN P4HB Protein disulfide-isomerase 8.02e-07 0.31
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 2.836e-06 0.34
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 3.716e-06 0.31
HKDC1_HUMAN HKDC1 Hexokinase HKDC1 5.025e-06 0.54
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 5.03e-06 0.30
IL5_MOUSE Il5 Interleukin-5 8.365e-06 0.30

Fumaric-acid

Q6RY99_RAT Tetraspanin 1.567e-44 0.50
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.335e-11 0.33
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 1.331e-10 0.53
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 2.023e-08 0.38
BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 6.837e-07 0.40
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 7.372e-07 0.38
O49150_SOLTU Lipoxygenase 1.716e-06 0.32
CAH3_HUMAN CA3 Carbonic anhydrase 3 4.154e-06 0.36