Results of Job: search_fff1e6c3-c943-4743-a20d-f24ef0055cba

Query Target Key Target Name Description P-Value MaxTC

Losartan

AGTR1_RABIT AGTR1 Type-1 angiotensin II receptor 0 1.00
AGTRB_RAT Agtr1b Type-1B angiotensin II receptor 0 1.00
AGTR1_BOVIN AGTR1 Type-1 angiotensin II receptor 2.233e-307 1.00
AGTR1_HUMAN AGTR1 Type-1 angiotensin II receptor 1.015e-186 1.00
AGTRA_RAT Agtr1 Type-1A angiotensin II receptor 5.498e-175 1.00
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 2.113e-116 1.00
AGTR1_CAVPO AGTR1 Type-1 angiotensin II receptor 1.461e-45 1.00
ACE_HUMAN ACE Angiotensin-converting enzyme 0.002788 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.8668 1.00
AGTR2_RAT Agtr2 Type-2 angiotensin II receptor 2.618e-207 0.69
A8K2H7_HUMAN C3AR1 Complement component 3a receptor 1, isoform CRA_a 2.835e-59 0.45
GPVI_HUMAN GP6 Platelet glycoprotein VI 1.542e-43 0.54
TLR7_HUMAN TLR7 Toll-like receptor 7 3.374e-26 0.39
POLI_HUMAN POLI DNA polymerase iota 9.748e-24 0.38
POLK_HUMAN POLK DNA polymerase kappa 2.331e-15 0.38
BRS3_MOUSE Brs3 Bombesin receptor subtype-3 5.656e-12 0.33
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 7.536e-12 0.46
EDNRA_HUMAN EDNRA Endothelin-1 receptor 4.096e-11 0.51
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 4.097e-10 0.46
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 2.043e-09 0.29
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 2.647e-09 0.33
ACATN_HUMAN SLC33A1 Acetyl-coenzyme A transporter 1 8.961e-08 0.31
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 2.588e-07 0.31

Amprenavir

Q9YQ12_9HIV1 protease Protease 7.282e-283 1.00
O90781_9PLVG HIV-1 protease HIV-1 protease 1.372e-261 1.00
Q72874_9HIV1 pol Pol polyprotein 2.778e-204 1.00
THAS_HUMAN TBXAS1 Thromboxane-A synthase 0.03839 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.7833 1.00
POL_HV1A2 gag-pol Gag-Pol polyprotein 1.226e-241 0.79
Q9YQ30_9PLVG HIV-1 protease HIV-1 protease 5.991e-104 0.34
RENI_HUMAN REN Renin 1.134e-47 0.37
CATD_BOVIN CTSD Cathepsin D 3.29e-41 0.33
POL_HV1H2 gag-pol Gag-Pol polyprotein 1.207e-36 0.39
MMP12_MOUSE Mmp12 Macrophage metalloelastase 1.275e-36 0.30
AMPB_MOUSE Rnpep Aminopeptidase B 1.097e-35 0.28
AMPL_BOVIN LAP3 Cytosol aminopeptidase 1.097e-35 0.28
KLK5_HUMAN KLK5 Kallikrein-5 2.663e-31 0.34
CATD_HUMAN CTSD Cathepsin D 2.759e-27 0.34
RORG_HUMAN RORC Nuclear receptor ROR-gamma 1.095e-26 0.39
PEPA5_HUMAN PGA5 Pepsin A-5 6.326e-23 0.37
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 1.165e-22 0.32
P88142_9HIV2 pol Pol polyprotein 3.749e-22 0.36
MEP1B_HUMAN MEP1B Meprin A subunit beta 9.693e-21 0.33
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 1.08e-20 0.31
CPNS1_PIG CAPNS1 Calpain small subunit 1 1.959e-20 0.30
POL_HV1BR gag-pol Gag-Pol polyprotein 2.42e-19 0.62
MMP2_MOUSE Mmp2 72 kDa type IV collagenase 1.265e-18 0.30
MMP9_MOUSE Mmp9 Matrix metalloproteinase-9 1.265e-18 0.30
CATE_HUMAN CTSE Cathepsin E 3.642e-18 0.34
BACE2_HUMAN BACE2 Beta-secretase 2 7.059e-18 0.33
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 8.104e-18 0.28
CATH_HUMAN CTSH Pro-cathepsin H 1.665e-15 0.30
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 2.887e-15 0.29
PEPC_HUMAN PGC Gastricsin 3.886e-15 0.34
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 9.215e-15 0.29
MMP3_HUMAN MMP3 Stromelysin-1 1.033e-14 0.41
BACE1_HUMAN BACE1 Beta-secretase 1 1.288e-14 0.33
CAN2_PIG CAPN2 Calpain-2 catalytic subunit 5.56e-13 0.30
ADA10_HUMAN ADAM10 Disintegrin and metalloproteinase domain-containing protein 10 7.676e-12 0.30
AMPX_VIBPR Bacterial leucyl aminopeptidase 1.339e-11 0.28
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 6.432e-11 0.36
MMP8_HUMAN MMP8 Neutrophil collagenase 1.114e-10 0.36
AMPN_MOUSE Anpep Aminopeptidase N 1.479e-10 0.28
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 2.628e-10 0.31
CATB_RAT Ctsb Cathepsin B 5.83e-10 0.28
MMP2_HUMAN MMP2 72 kDa type IV collagenase 6.138e-10 0.40
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.712e-09 0.30
APH1A_HUMAN APH1A Gamma-secretase subunit APH-1A 1.889e-09 0.37
APH1B_HUMAN APH1B Gamma-secretase subunit APH-1B 1.889e-09 0.37
NICA_HUMAN NCSTN Nicastrin 1.889e-09 0.37
PEN2_HUMAN PSENEN Gamma-secretase subunit PEN-2 1.906e-09 0.37
PSN2_HUMAN PSEN2 Presenilin-2 1.958e-09 0.37
CATB_HUMAN CTSB Cathepsin B 2.467e-09 0.35
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 2.745e-09 0.29
PSN1_HUMAN PSEN1 Presenilin-1 4.501e-09 0.37
CARP_RHICH Rhizopuspepsin 4.981e-09 0.28
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 6.552e-09 0.29
MMP1_HUMAN MMP1 Interstitial collagenase 7.496e-09 0.36
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 1.413e-08 0.40
TIMP3_RAT Timp3 Metalloproteinase inhibitor 3 1.969e-08 0.30
Q53I59_TRYCR PDEC Phosphodiesterase 2.065e-08 0.30
PEPA_PIG PGA Pepsin A 2.922e-08 0.34
RENI_RAT Ren1 Renin 3.191e-08 0.31
MMP9_RAT Mmp9 Matrix metalloproteinase-9 5.911e-08 0.30
RORB_HUMAN RORB Nuclear receptor ROR-beta 9.067e-08 0.33
AMPL_HUMAN LAP3 Cytosol aminopeptidase 1.558e-07 0.29
MMP13_HUMAN MMP13 Collagenase 3 1.687e-07 0.40
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 5.841e-07 0.31
AMPB_RAT Rnpep Aminopeptidase B 5.904e-07 0.28
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 5.904e-07 0.28
Q4U254_9ENTO protease Protease 1.276e-06 0.31
RORA_HUMAN RORA Nuclear receptor ROR-alpha 1.431e-06 0.33
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 1.683e-06 0.29
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 1.683e-06 0.29
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 1.683e-06 0.29
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 1.683e-06 0.29
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 1.683e-06 0.29
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 1.683e-06 0.29
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 1.683e-06 0.29
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 1.683e-06 0.29
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 1.683e-06 0.29
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 1.683e-06 0.29
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 1.683e-06 0.29
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 1.683e-06 0.29
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 1.683e-06 0.29
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 1.683e-06 0.29
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 1.683e-06 0.29
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 1.683e-06 0.29
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 1.683e-06 0.29
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 1.683e-06 0.29
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 3.241e-06 0.33
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 3.806e-06 0.29
BKRB2_RAT Bdkrb2 B2 bradykinin receptor 9.991e-06 0.29

Pentamidine

ACRO_PIG ACR Acrosin 2.389e-247 1.00
SAT1_HUMAN SAT1 Diamine acetyltransferase 1 2.9e-124 1.00
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 1.872e-57 1.00
TRY1_HUMAN PRSS1 Trypsin-1 1.473e-43 1.00
S100B_HUMAN S100B Protein S100-B 1.735e-32 1.00
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 3.937e-30 1.00
AOC1_HUMAN AOC1 Amiloride-sensitive amine oxidase [copper-containing] 3.693e-26 1.00
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 6.746e-21 1.00
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 4.197e-20 1.00
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 7.339e-20 1.00
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 2.207e-06 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.882e-05 1.00
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 0.001681 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.003008 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 0.0173 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.03486 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 0.03766 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.04984 1.00
STRP_STRP1 ska Streptokinase A 0.1079 1.00
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 0.3005 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.3287 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.6581 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.6956 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.7051 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.8581 1.00
KLK_PIG Glandular kallikrein 5.215e-163 0.56
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 8.108e-115 0.44
S100B_RAT S100b Protein S100-B 5.939e-100 0.53
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.921e-82 0.48
FA10_BOVIN F10 Coagulation factor X 3.18e-75 0.62
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 2.935e-65 0.50
UROK_HUMAN PLAU Urokinase-type plasminogen activator 1.62e-49 0.56
THRB_BOVIN F2 Prothrombin 2.87e-41 0.62
TRY1_BOVIN Cationic trypsin 9.424e-41 0.56
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 2.317e-40 0.32
O69638_MYCTO Hydrolase, alpha/beta hydrolase fold family 5.351e-37 0.29
HRH3_RAT Hrh3 Histamine H3 receptor 5.633e-36 0.40
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 8.011e-33 0.35
ENTK_HUMAN TMPRSS15 Enteropeptidase 3.111e-32 0.36
PLMN_HUMAN PLG Plasminogen 4.771e-29 0.56
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 8.234e-29 0.35
LSS_HUMAN LSS Lanosterol synthase 1.122e-28 0.39
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 3.198e-28 0.39
THRB_HUMAN F2 Prothrombin 1.005e-25 0.58
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 2.433e-25 0.34
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 2.44e-21 0.45
ACRO_HUMAN ACR Acrosin 3.128e-20 0.42
TPA_HUMAN PLAT Tissue-type plasminogen activator 2.228e-19 0.36
DCAM_RAT Amd1 S-adenosylmethionine decarboxylase proenzyme 2.805e-19 0.36
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.903e-19 0.40
PAR16_HUMAN PARP16 Protein mono-ADP-ribosyltransferase PARP16 1.594e-18 0.35
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 3.743e-18 0.43
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 1.47e-17 0.62
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 1.544e-17 0.36
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 2.007e-17 0.35
Q9GPQ4_TRYVI IAG-nucleoside hydrolase 4.583e-17 0.33
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.11e-16 0.36
HRH3_CAVPO HRH3 Histamine H3 receptor 1.11e-16 0.36
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 2.22e-16 0.34
ITB3_HUMAN ITGB3 Integrin beta-3 6.661e-16 0.45
KLK1_HUMAN KLK1 Kallikrein-1 8.771e-15 0.48
FA10_HUMAN F10 Coagulation factor X 4.641e-14 0.50
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 9.504e-14 0.30
HRH3_HUMAN HRH3 Histamine H3 receptor 1.102e-13 0.36
SQHC_ALIAD shc Squalene--hopene cyclase 2.506e-13 0.38
GP174_HUMAN GPR174 Probable G-protein coupled receptor 174 7.311e-13 0.28
P2Y10_HUMAN P2RY10 Putative P2Y purinoceptor 10 1.02e-12 0.29
ERG2_YEAST ERG2 C-8 sterol isomerase 1.228e-12 0.37
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 1.893e-12 0.48
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 1.935e-12 0.35
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 2.525e-12 0.41
HRH1_HUMAN HRH1 Histamine H1 receptor 1.299e-11 0.34
HRH2_HUMAN HRH2 Histamine H2 receptor 1.866e-11 0.33
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 8.505e-11 0.37
KLK8_HUMAN KLK8 Kallikrein-8 1.369e-10 0.28
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 1.758e-10 0.45
ESR1_HUMAN ESR1 Estrogen receptor 2.103e-10 0.39
CHLE_HORSE BCHE Cholinesterase 2.32e-10 0.36
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 2.525e-10 0.35
PAR14_HUMAN PARP14 Protein mono-ADP-ribosyltransferase PARP14 3.352e-10 0.35
KLK4_HUMAN KLK4 Kallikrein-4 9.181e-10 0.28
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.208e-09 0.40
AHR_RABIT AHR Aryl hydrocarbon receptor 1.628e-09 0.29
V1AR_RAT Avpr1a Vasopressin V1a receptor 6.429e-09 0.33
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.371e-08 0.35
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 1.751e-08 0.34
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 1.922e-08 0.33
RARB_HUMAN RARB Retinoic acid receptor beta 2.21e-08 0.46
CBPB1_PIG CPB1 Carboxypeptidase B 2.824e-08 0.34
HRH3_MOUSE Hrh3 Histamine H3 receptor 3.231e-08 0.30
STS_HUMAN STS Steryl-sulfatase 3.869e-08 0.35
FA7_HUMAN F7 Coagulation factor VII 5.098e-08 0.34
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 6.136e-08 0.34
THA_HUMAN THRA Thyroid hormone receptor alpha 6.938e-08 0.40
ACES_ELEEL ache Acetylcholinesterase 8.192e-08 0.36
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 1.342e-07 0.30
A4_HUMAN APP Amyloid-beta precursor protein 1.591e-07 0.33
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 1.619e-07 0.36
GGPPS_HUMAN GGPS1 Geranylgeranyl pyrophosphate synthase 2.014e-07 0.30
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 2.06e-07 0.36
LYAG_MOUSE Gaa Lysosomal alpha-glucosidase 2.362e-07 0.29
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 2.651e-07 0.30
CP19A_HUMAN CYP19A1 Aromatase 3.506e-07 0.39
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 3.662e-07 0.29
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 8.351e-07 0.37
AOC1_RAT Aoc1 Amiloride-sensitive amine oxidase [copper-containing] 9.396e-07 0.29
HMOX2_RAT Hmox2 Heme oxygenase 2 1.225e-06 0.33
LSS_RAT Lss Lanosterol synthase 1.479e-06 0.32
HEPS_HUMAN HPN Serine protease hepsin 1.584e-06 0.33
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.594e-06 0.38
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.886e-06 0.32
TRYP_PIG Trypsin 3.189e-06 0.33
AGP1_YEAST AGP1 General amino acid permease AGP1 4.296e-06 0.30
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 7.575e-06 0.36
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 7.707e-06 0.30
O61059_LEIME LmGT2 Glucose transporter 8.107e-06 0.49
LYOX_HUMAN LOX Protein-lysine 6-oxidase 8.755e-06 0.28
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 9.847e-06 0.29

Naftifine

CRTN_STAAE crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 2.245e-240 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.001101 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.1852 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.3505 1.00
CRTN_STAAM crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 1.352e-109 0.58
CRTN_STAAW crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 1.155e-100 0.58
CRTN_STAA3 crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 1.267e-98 0.58
CLAT_RAT Chat Choline O-acetyltransferase 2.45e-70 0.36
CLAT_HUMAN CHAT Choline O-acetyltransferase 3.422e-42 0.35
ANM1_RAT Prmt1 Protein arginine N-methyltransferase 1 6.541e-39 0.40
INAR1_HUMAN IFNAR1 Interferon alpha/beta receptor 1 7.142e-37 0.29
ERG1_HUMAN SQLE Squalene monooxygenase 3.051e-20 0.61
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 4.441e-16 0.35
ERG7_PNECA ERG7 Lanosterol synthase 3.042e-14 0.31
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 8.628e-12 0.38
AMPN_MOUSE Anpep Aminopeptidase N 1.089e-11 0.31
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 3.648e-09 0.31
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 3.194e-08 0.34
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 4.633e-08 0.30
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 1.325e-07 0.30
TF65_HUMAN RELA Transcription factor p65 3.657e-06 0.35
CBPA1_BOVIN CPA1 Carboxypeptidase A1 6.244e-06 0.31
AMP1_PLAFQ M1 family aminopeptidase 7.434e-06 0.30

Naltrexone

OPRK_CAVPO OPRK1 Kappa-type opioid receptor 1.317e-230 1.00
OPRD_HUMAN OPRD1 Delta-type opioid receptor 5.216e-220 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 3.23e-199 1.00
OPRM_MOUSE Oprm1 Mu-type opioid receptor 7.379e-194 1.00
OPRM_CAVPO OPRM1 Mu-type opioid receptor 3.55e-173 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 3.203e-171 1.00
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 8.061e-167 1.00
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.819e-142 1.00
OPRD_RAT Oprd1 Delta-type opioid receptor 6.604e-141 1.00
OPRM_RAT Oprm1 Mu-type opioid receptor 9.234e-126 1.00
OPRK_RAT Oprk1 Kappa-type opioid receptor 8.673e-87 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.001938 1.00
OPRM_BOVIN OPRM1 Mu-type opioid receptor 8.487e-142 0.68
TLR4_MOUSE Tlr4 Toll-like receptor 4 4.806e-73 0.72
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 6.762e-68 0.33
OPRX_HUMAN OPRL1 Nociceptin receptor 1.574e-23 0.64
OPRX_CAVPO OPRL1 Nociceptin receptor 3.637e-22 0.51
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 3.664e-15 0.42

Adenosine

AA3R_RAT Adora3 Adenosine receptor A3 3.276e-218 1.00
ADK_TOXGO AK Adenosine kinase 2.669e-217 1.00
AA2AR_RAT Adora2a Adenosine receptor A2a 7.887e-193 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 2.449e-168 1.00
ADK_HUMAN ADK Adenosine kinase 7.454e-145 1.00
AA1R_HUMAN ADORA1 Adenosine receptor A1 1.425e-137 1.00
AA1R_CAVPO ADORA1 Adenosine receptor A1 7.004e-125 1.00
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 8.005e-103 1.00
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 1.081e-08 1.00
DPP4_HUMAN DPP4 Dipeptidyl peptidase 4 0.9883 1.00
AA1R_RAT Adora1 Adenosine receptor A1 2.283e-304 0.74
OXGR1_RAT Oxgr1 2-oxoglutarate receptor 1 2.724e-248 0.66
SAHH_HUMAN AHCY Adenosylhomocysteinase 2.126e-233 0.83
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 3.912e-227 0.64
ADOK_MYCTO adoK Adenosine kinase 9.719e-191 0.51
MBTA_MYCTU mbtA Salicyl-AMP ligase / salicyl-S-ArCP synthetase 1.94e-190 0.59
DCAM_HUMAN AMD1 S-adenosylmethionine decarboxylase proenzyme 1.602e-180 0.74
DOT1L_HUMAN DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 5.541e-179 0.62
AA1R_CHICK ADORA1 Adenosine receptor A1 1.112e-178 0.63
C3SIU2_ECOLX metJ Met repressor 5.915e-177 0.60
SAHH_RAT Ahcy Adenosylhomocysteinase 8.87e-176 0.67
MTAP_MOUSE Mtap S-methyl-5'-thioadenosine phosphorylase 4.884e-158 0.71
S28A2_HUMAN SLC28A2 Sodium/nucleoside cotransporter 2 2.75e-156 0.49
AA1R_RABIT ADORA1 Adenosine receptor A1 1.525e-150 0.48
AA3R_RABIT ADORA3 Adenosine receptor A3 9.214e-148 0.48
DNPH1_HUMAN DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 3.799e-147 0.46
DNPH1_RAT Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 7.885e-145 0.46
BIP_HUMAN HSPA5 Endoplasmic reticulum chaperone BiP 3.331e-137 0.66
SAHH_MOUSE Ahcy Adenosylhomocysteinase 4.771e-133 0.66
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 1.472e-130 0.62
SPEE_HUMAN SRM Spermidine synthase 1.673e-114 0.59
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 8.31e-114 0.63
IMDH1_HUMAN IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 4.665e-111 0.50
P2RY1_RAT P2ry1 P2Y purinoceptor 1 8.946e-111 0.65
CDD_MOUSE Cda Cytidine deaminase 2.685e-109 0.60
G3PC_LEIME GAPC Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 3.297e-109 0.39
Q99MI5_RAT LOC100912604 Spermidine synthase 9.277e-103 0.59
SAHH_PLAF7 Adenosylhomocysteinase 1.377e-101 0.57
ADA_BOVIN ADA Adenosine deaminase 5.713e-101 0.74
I6YFP0_MYCTU birA Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase) 2.916e-98 0.44
SYQ_HUMAN QARS1 Glutamine--tRNA ligase 4.874e-97 0.57
KAD2_RAT Ak2 Adenylate kinase 2, mitochondrial 1.676e-96 0.65
G3P_HUMAN GAPDH Glyceraldehyde-3-phosphate dehydrogenase 5.312e-96 0.68
ASNS_HUMAN ASNS Asparagine synthetase [glutamine-hydrolyzing] 7.01e-94 0.53
ADCY5_HUMAN ADCY5 Adenylate cyclase type 5 5.989e-93 0.43
ENPP1_RAT Enpp1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 1.052e-92 0.63
KAD3_RAT Ak3 GTP:AMP phosphotransferase AK3, mitochondrial 2.332e-91 0.65
SPSY_HUMAN SMS Spermine synthase 1.666e-88 0.59
IMDH2_MOUSE Impdh2 Inosine-5'-monophosphate dehydrogenase 2 7.381e-88 0.50
NADK_HUMAN NADK NAD kinase 7.547e-88 0.62
PARG_BOVIN PARG Poly(ADP-ribose) glycohydrolase 9.666e-88 0.54
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 3.455e-87 0.65
PQSA_PSEAE pqsA Anthranilate--CoA ligase 1.541e-85 0.55
HSP7C_HUMAN HSPA8 Heat shock cognate 71 kDa protein 2.681e-85 0.66
P2Y11_HUMAN P2RY11 P2Y purinoceptor 11 1.042e-84 0.63
CDD_HUMAN CDA Cytidine deaminase 1.641e-83 0.45
ADA_MOUSE Ada Adenosine deaminase 6.809e-81 0.57
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 9.784e-81 0.45
MACD1_HUMAN MACROD1 ADP-ribose glycohydrolase MACROD1 2.121e-79 0.64
MACD2_HUMAN MACROD2 ADP-ribose glycohydrolase MACROD2 2.121e-79 0.64
NADK1_LISMF nadK1 NAD kinase 1 5.016e-79 0.63
NADK_STAAC nadK NAD kinase 5.016e-79 0.63
HSP7C_BOVIN HSPA8 Heat shock cognate 71 kDa protein 1.436e-78 0.63
WALK_STAAU walK Sensor protein kinase WalK 1.436e-78 0.63
DHE3_BOVIN GLUD1 Glutamate dehydrogenase 1, mitochondrial 3.582e-78 0.50
SYRC_HUMAN RARS1 Arginine--tRNA ligase, cytoplasmic 3.718e-78 0.49
P2RY4_RAT P2ry4 P2Y purinoceptor 4 2.194e-77 0.65
KMT5C_HUMAN KMT5C Histone-lysine N-methyltransferase KMT5C 3.712e-77 0.62
SETB1_HUMAN SETDB1 Histone-lysine N-methyltransferase SETDB1 3.712e-77 0.62
KTHY_HUMAN DTYMK Thymidylate kinase 4.801e-77 0.46
METK1_RAT Mat1a S-adenosylmethionine synthase isoform type-1 6.228e-76 0.51
ENPL_PIG HSP90B1 Endoplasmin 2.225e-75 0.60
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 4.875e-75 0.49
RN5A_MOUSE Rnasel 2-5A-dependent ribonuclease 7.246e-73 0.54
SYS_ECOLI serS Serine--tRNA ligase 7.398e-73 0.58
METK2_RAT Mat2a S-adenosylmethionine synthase isoform type-2 5.501e-72 0.58
MSHC_MYCTU mshC L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 8.422e-71 0.57
ANM7_HUMAN PRMT7 Protein arginine N-methyltransferase 7 1.757e-70 0.57
Q4VQ11_PIG Adenosine receptor A1 1.265e-69 0.64
SAHH2_HUMAN AHCYL1 S-adenosylhomocysteine hydrolase-like protein 1 9.019e-69 0.37
SETD2_HUMAN SETD2 Histone-lysine N-methyltransferase SETD2 1.516e-68 0.55
RN5A_HUMAN RNASEL 2-5A-dependent ribonuclease 1.797e-67 0.54
SYD_ECOLI aspS Aspartate--tRNA ligase 1.797e-67 0.54
RNAS1_HUMAN RNASE1 Ribonuclease pancreatic 4.043e-67 0.45
RNAS2_HUMAN RNASE2 Non-secretory ribonuclease 4.043e-67 0.45
Q9HWG3_PSEAE pchD Pyochelin biosynthesis protein PchD 1.972e-66 0.53
PANE_ECOLI panE 2-dehydropantoate 2-reductase 2.186e-66 0.42
SNAT_SHEEP AANAT Serotonin N-acetyltransferase 1.545e-65 0.30
RASK_HUMAN KRAS GTPase KRas 3.449e-64 0.34
P2RX5_RAT P2rx5 P2X purinoceptor 5 3.449e-63 0.62
P2RX6_RAT P2rx6 P2X purinoceptor 6 3.449e-63 0.62
SYY_ECOLI tyrS Tyrosine--tRNA ligase 1.414e-62 0.50
IF4E_RABIT EIF4E Eukaryotic translation initiation factor 4E 5.288e-61 0.38
HARS1_HUMAN HARS1 Histidine--tRNA ligase, cytoplasmic 8.185e-61 0.49
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 4.664e-58 0.74
ADCY2_RAT Adcy2 Adenylate cyclase type 2 1.851e-56 0.52
BIRA_ECOLI birA Bifunctional ligase/repressor BirA 4.405e-56 0.45
SYI_ECOLI ileS Isoleucine--tRNA ligase 3.675e-55 0.53
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 7.935e-55 0.50
IUNH_CRIFA IUNH Inosine-uridine preferring nucleoside hydrolase 1.609e-54 0.48
O15727_TRYBB Inosine-adenosine-guanosine-nucleoside hydrolase 1.609e-54 0.48
ENTE_ECOLI entE Enterobactin synthase component E 1.673e-53 0.34
P96884_MYCTO birA BirA bifunctional protein 1.344e-52 0.44
ADA_HUMAN ADA Adenosine deaminase 6.375e-52 0.67
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 7.161e-52 0.59
UBA7_HUMAN UBA7 Ubiquitin-like modifier-activating enzyme 7 1.398e-50 0.40
MENB_MYCTU menB 1,4-dihydroxy-2-naphthoyl-CoA synthase 2.619e-50 0.32
S29A1_RAT Slc29a1 Equilibrative nucleoside transporter 1 2.434e-47 0.59
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 8.046e-46 0.62
ENTP1_BOVIN ENTPD1 Ectonucleoside triphosphate diphosphohydrolase 1 2.649e-45 0.36
Q70E71_9ENTE aac(6')-Ii Aminoglycoside N(6')-acetyltransferase 3.091e-45 0.33
Q8TA74_HEMPU Ryanodine receptor 4.575e-43 0.36
SYL_ECOLI leuS Leucine--tRNA ligase 1.575e-42 0.53
P2RX4_RAT P2rx4 P2X purinoceptor 4 1.074e-39 0.62
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 2.541e-39 0.35
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 6.282e-39 0.51
SUV91_HUMAN SUV39H1 Histone-lysine N-methyltransferase SUV39H1 7.367e-38 0.62
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 8.545e-38 0.62
POLG_POL1M Genome polyprotein 2.223e-37 0.30
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 3.575e-37 0.43
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 4.624e-37 0.53
PYRF_YEAST URA3 Orotidine 5'-phosphate decarboxylase 1.042e-36 0.37
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 1.054e-35 0.64
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 1.193e-35 0.65
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 1.463e-35 0.63
A0A0E7NXW5_STAAU birA Bifunctional ligase/repressor BirA 8.665e-35 0.45
PANC_MYCTU panC Pantothenate synthetase 1.05e-33 0.56
NNMT_HUMAN NNMT Nicotinamide N-methyltransferase 1.875e-33 0.46
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 1.947e-33 0.64
AA1R_BOVIN ADORA1 Adenosine receptor A1 2.328e-33 0.68
PARG_HUMAN PARG Poly(ADP-ribose) glycohydrolase 2.552e-33 0.54
GPR17_HUMAN GPR17 Uracil nucleotide/cysteinyl leukotriene receptor 6.812e-33 0.44
AMPD1_RABIT AMPD1 AMP deaminase 1 9.108e-33 0.41
UBA6_HUMAN UBA6 Ubiquitin-like modifier-activating enzyme 6 1.876e-32 0.40
ADCY5_RAT Adcy5 Adenylate cyclase type 5 3.763e-32 0.52
BPL1_HUMAN HLCS Biotin--protein ligase 1.52e-31 0.45
B4EH87_BURCJ Lectin 4.081e-31 0.31
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 5.567e-31 0.68
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 1.313e-30 0.68
SYMC_HUMAN MARS1 Methionine--tRNA ligase, cytoplasmic 2.15e-30 0.59
DCAM_RAT Amd1 S-adenosylmethionine decarboxylase proenzyme 8.167e-30 0.74
KITH_RAT Tk1 Thymidine kinase, cytosolic 9.264e-30 0.48
PUR6_CHICK AIRC Multifunctional protein ADE2 1.853e-29 0.38
AA2AR_MOUSE Adora2a Adenosine receptor A2a 1.552e-28 0.36
NMT_YEAST NMT1 Glycylpeptide N-tetradecanoyltransferase 2.783e-27 0.34
CDK12_HUMAN CDK12 Cyclin-dependent kinase 12 5.245e-27 0.33
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 3.938e-26 0.65
MGMT_HUMAN MGMT Methylated-DNA--protein-cysteine methyltransferase 5.406e-26 0.34
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 2.386e-25 0.64
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 2.376e-24 0.39
EZH1_HUMAN EZH1 Histone-lysine N-methyltransferase EZH1 2.878e-23 0.62
HEXB_HUMAN HEXB Beta-hexosaminidase subunit beta 4.633e-23 0.28
KITH_VZVD TK Thymidine kinase 2.79e-22 0.34
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 5.378e-22 0.65
ADK_RAT Adk Adenosine kinase 5.527e-22 0.81
P2RX1_RAT P2rx1 P2X purinoceptor 1 3.264e-21 0.43
SYTC_HUMAN TARS1 Threonine--tRNA ligase 1, cytoplasmic 1.768e-20 0.55
IF4E_MOUSE Eif4e Eukaryotic translation initiation factor 4E 2.652e-20 0.32
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 1.096e-19 0.44
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 2.904e-18 0.64
5NTD_HUMAN NT5E 5'-nucleotidase 2.928e-18 0.63
GLCM_BOVIN GBA Lysosomal acid glucosylceramidase 4.879e-18 0.29
HEXA_HUMAN HEXA Beta-hexosaminidase subunit alpha 7.088e-18 0.28
KAPCA_HUMAN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 7.317e-18 0.54
ADH1A_HUMAN ADH1A Alcohol dehydrogenase 1A 1.218e-17 0.49
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 1.11e-16 0.42
KMT2A_HUMAN KMT2A Histone-lysine N-methyltransferase 2A 1.11e-16 0.62
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 1.11e-16 0.29
Q9HX69_PSEAE rocR RocR 1.11e-16 0.32
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 3.331e-16 0.64
HPPK_ECOLI folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 8.882e-16 0.47
P2RX2_RAT P2rx2 P2X purinoceptor 2 1.776e-15 0.62
G3PG_TRYCR Glyceraldehyde-3-phosphate dehydrogenase, glycosomal 3.109e-15 0.29
AA1R_MOUSE Adora1 Adenosine receptor A1 1.765e-14 0.50
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 5.24e-14 0.43
INMT_HUMAN INMT Indolethylamine N-methyltransferase 9.681e-14 0.62
KITH_HUMAN TK1 Thymidine kinase, cytosolic 1.01e-13 0.32
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 2.022e-13 0.39
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 2.802e-13 0.39
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 3.256e-13 0.54
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 4.526e-13 0.32
5NTD_RAT Nt5e 5'-nucleotidase 7.679e-13 0.63
M9TGV3_MYCTX inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 1.405e-12 0.43
RAB7A_HUMAN RAB7A Ras-related protein Rab-7a 1.788e-12 0.39
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 2.4e-12 0.39
CCNK_HUMAN CCNK Cyclin-K 2.492e-12 0.33
CD69_HUMAN CD69 Early activation antigen CD69 4.251e-12 0.30
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 4.251e-12 0.30
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 7.334e-12 0.62
Q9Y0I0_9TRYP AT1 Adenosine transporter 1 5.735e-11 0.51
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 6.927e-11 0.59
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 7.359e-11 0.49
ENPL_CANLF HSP90B1 Endoplasmin 7.859e-11 0.62
P2Y12_RAT P2ry12 P2Y purinoceptor 12 8.338e-11 0.63
TYPH_HUMAN TYMP Thymidine phosphorylase 8.646e-11 0.37
SYT_YERPE thrS Threonine--tRNA ligase 1.325e-10 0.55
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 3.409e-10 0.31
EZH2_HUMAN EZH2 Histone-lysine N-methyltransferase EZH2 4.657e-10 0.62
E1BN64_BOVIN PDE3B Phosphodiesterase 1.636e-09 0.32
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 2.491e-09 0.59
DCPS_HUMAN DCPS m7GpppX diphosphatase 2.505e-09 0.38
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 3.473e-09 0.64
SMYD2_HUMAN SMYD2 N-lysine methyltransferase SMYD2 9.103e-09 0.62
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 9.952e-09 0.34
GALR3_HUMAN GALR3 Galanin receptor type 3 2.697e-08 0.59
LUCI_AQULA Luciferin 4-monooxygenase 3.393e-08 0.41
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 4.652e-08 0.35
Q56950_YERPE ybtE Salicyl-AMP ligase YbtE 6.022e-08 0.53
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 9.26e-08 0.39
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 2.112e-07 0.62
DPOLB_HUMAN POLB DNA polymerase beta 2.151e-07 0.44
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 2.339e-07 0.36
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 5.944e-07 0.33
AA2BR_RAT Adora2b Adenosine receptor A2b 6.318e-07 0.60
Q9WKE8_9HIV1 reverse transcriptase Reverse transcriptase 7.817e-07 0.48
CLAT_HUMAN CHAT Choline O-acetyltransferase 8.733e-07 0.36
PAX8_HUMAN PAX8 Paired box protein Pax-8 1.608e-06 0.59
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 1.651e-06 0.60
DNLJ_STAAU ligA DNA ligase 1.959e-06 0.58
HPRT_HUMAN HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 3.047e-06 0.44
F16P1_RAT Fbp1 Fructose-1,6-bisphosphatase 1 5.011e-06 0.30
O39930_9HEPC NS5b RNA-directed RNA polymerase 5.206e-06 0.48
COT2_HUMAN NR2F2 COUP transcription factor 2 9.476e-06 0.32

Lisinopril

ACE_HUMAN ACE Angiotensin-converting enzyme 3.135e-212 1.00
ACE_RABIT ACE Angiotensin-converting enzyme 5.335e-173 1.00
NTR2_HUMAN NTSR2 Neurotensin receptor type 2 9.109e-182 0.44
ACE_RAT Ace Angiotensin-converting enzyme 5.903e-146 0.70
PRSS8_HUMAN PRSS8 Prostasin 1.329e-130 0.52
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 1.903e-125 0.42
TRFR_MOUSE Trhr Thyrotropin-releasing hormone receptor 6.092e-123 0.43
Q9ERT1_MOUSE TRH-R2 Thyrotropin-releasing hormone receptor 2 5.185e-122 0.37
PPCE_PIG PREP Prolyl endopeptidase 8.071e-122 0.48
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 9.435e-115 0.43
NTR1_RAT Ntsr1 Neurotensin receptor type 1 5.689e-113 0.44
BRCA1_HUMAN BRCA1 Breast cancer type 1 susceptibility protein 1.337e-108 0.41
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 1.437e-102 0.49
PPCE_BOVIN PREP Prolyl endopeptidase 7.537e-99 0.52
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 3.718e-96 0.34
Q9R297_RAT Mlnr Motilin receptor 1.182e-92 0.37
GYS1_HUMAN GYS1 Glycogen [starch] synthase, muscle 1.185e-90 0.33
THRB_HUMAN F2 Prothrombin 7.599e-89 0.55
TRY1_BOVIN Cationic trypsin 1.309e-86 0.48
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 1.571e-81 0.40
NPFF2_RAT Npffr2 Neuropeptide FF receptor 2 2.337e-81 0.40
PPCE_MOUSE Prep Prolyl endopeptidase 2.297e-80 0.42
CBPB2_HUMAN CPB2 Carboxypeptidase B2 3.087e-80 0.40
POLG_WNV Genome polyprotein 6.181e-80 0.36
XPP2_HUMAN XPNPEP2 Xaa-Pro aminopeptidase 2 1.429e-79 0.41
OPRM_RAT Oprm1 Mu-type opioid receptor 3.76e-77 0.50
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 4.292e-75 0.40
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 4.921e-74 0.39
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 8.518e-74 0.35
MLX_HUMAN MLX Max-like protein X 3.392e-73 0.34
XPP2_RAT Xpnpep2 Xaa-Pro aminopeptidase 2 4.531e-73 0.41
NEP_RABIT MME Neprilysin 1.243e-67 0.54
NEP_RAT Mme Neprilysin 1.848e-64 0.52
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 3.868e-62 0.37
SORT_HUMAN SORT1 Sortilin 4.741e-62 0.36
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 1.815e-61 0.34
OPRD_RAT Oprd1 Delta-type opioid receptor 1.582e-59 0.42
XPP1_HUMAN XPNPEP1 Xaa-Pro aminopeptidase 1 2.285e-59 0.41
TRFR_HUMAN TRHR Thyrotropin-releasing hormone receptor 1.392e-58 0.31
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 2.034e-58 0.48
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 4.865e-58 0.41
ACE_MOUSE Ace Angiotensin-converting enzyme 3.24e-55 0.70
TPP2_RAT Tpp2 Tripeptidyl-peptidase 2 5.852e-55 0.42
GHRHR_RAT Ghrhr Growth hormone-releasing hormone receptor 1.33e-54 0.32
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 1.797e-54 0.39
PEPD_HUMAN PEPD Xaa-Pro dipeptidase 5.719e-54 0.43
Q9NAW4_PLAFA Cysteine protease falcipain-3 1.199e-53 0.35
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 1.787e-53 0.39
KLK3_HUMAN KLK3 Prostate-specific antigen 3.297e-51 0.31
PPCE_HUMAN PREP Prolyl endopeptidase 9.196e-51 0.42
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.148e-50 0.42
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 2.853e-50 0.55
RENI_RAT Ren1 Renin 1.01e-49 0.33
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.558e-49 0.42
OPRM_CAVPO OPRM1 Mu-type opioid receptor 2.536e-49 0.42
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 6.505e-48 0.43
TR10A_HUMAN TNFRSF10A Tumor necrosis factor receptor superfamily member 10A 2.677e-45 0.28
POLG_DEN26 Genome polyprotein 4.054e-45 0.32
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 1.965e-44 0.39
BXA1_CLOBH botA Botulinum neurotoxin type A 2.705e-44 0.33
PPCE_ELIME f1pep1 Prolyl endopeptidase 8.416e-44 0.35
F1SH20_PIG TRHDE Uncharacterized protein 8.011e-43 0.33
BIRC7_HUMAN BIRC7 Baculoviral IAP repeat-containing protein 7 5.166e-42 0.33
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 8.604e-42 0.37
DPP4_MOUSE Dpp4 Dipeptidyl peptidase 4 9.898e-42 0.48
TRFR_RAT Trhr Thyrotropin-releasing hormone receptor 1.812e-41 0.33
TRYB1_RAT Tpsab1 Tryptase 1.271e-39 0.31
TRYT_CANLF Tryptase 1.271e-39 0.31
NMUR1_MOUSE Nmur1 Neuromedin-U receptor 1 2.261e-39 0.31
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 4.143e-38 0.32
IL2RA_HUMAN IL2RA Interleukin-2 receptor subunit alpha 4.754e-38 0.30
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 5.885e-38 0.48
EPOR_HUMAN EPOR Erythropoietin receptor 3.46e-37 0.31
DPP2_HUMAN DPP7 Dipeptidyl peptidase 2 5.614e-37 0.44
CTRA_BOVIN Chymotrypsinogen A 1.475e-36 0.39
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 1.557e-36 0.32
SURA_ECOLI surA Chaperone SurA 1.172e-35 0.28
PLMN_HUMAN PLG Plasminogen 4.554e-35 0.49
NEP_HUMAN MME Neprilysin 6.682e-35 0.48
MMP3_HUMAN MMP3 Stromelysin-1 1.172e-34 0.50
TRY1_HUMAN PRSS1 Trypsin-1 2.178e-34 0.41
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 7.074e-34 0.40
TRY3_HUMAN PRSS3 Trypsin-3 3.755e-33 0.32
DEF_MYCTU def Peptide deformylase 6.171e-33 0.31
ITA4_HUMAN ITGA4 Integrin alpha-4 1.08e-32 0.41
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 2.964e-32 0.46
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 4.875e-32 0.39
DAPE_HAEIN dapE Succinyl-diaminopimelate desuccinylase 1.944e-31 0.39
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 1.988e-31 0.33
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 4.636e-31 0.70
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 7.026e-31 0.33
THRB_BOVIN F2 Prothrombin 1.271e-30 0.42
AMPL_HUMAN LAP3 Cytosol aminopeptidase 8.669e-30 0.43
DPP8_HUMAN DPP8 Dipeptidyl peptidase 8 1.143e-29 0.47
CMA1_HUMAN CMA1 Chymase 6.579e-29 0.39
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 7.153e-29 0.35
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.546e-28 0.40
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 2.866e-28 0.31
CBPA1_BOVIN CPA1 Carboxypeptidase A1 3.731e-28 0.35
NK2R_RAT Tacr2 Substance-K receptor 7.161e-28 0.43
PPCE_RAT Prep Prolyl endopeptidase 7.993e-28 0.42
IGA_NEIGO iga IgA-specific serine endopeptidase autotransporter 2.325e-27 0.34
NRP1_RAT Nrp1 Neuropilin-1 2.592e-27 0.37
ITB1_HUMAN ITGB1 Integrin beta-1 6.703e-27 0.41
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 8.67e-27 0.33
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 1.407e-26 0.33
NK1R_CAVPO TACR1 Substance-P receptor 1.513e-26 0.43
CD4_HUMAN CD4 T-cell surface glycoprotein CD4 1.728e-26 0.33
BKRB2_RABIT BDKRB2 B2 bradykinin receptor 2.603e-26 0.34
NK1R_RAT Tacr1 Substance-P receptor 6.675e-26 0.50
Q95PM0_TRYBR rhodesain Cysteine protease 1.073e-25 0.37
DEF_STRPN def Peptide deformylase 1.372e-25 0.37
AMPN_HUMAN ANPEP Aminopeptidase N 1.44e-25 0.47
CALRL_RAT Calcrl Calcitonin gene-related peptide type 1 receptor 1.448e-25 0.30
CATE_HUMAN CTSE Cathepsin E 1.704e-25 0.31
A4HSF7_LEIIN TRYR Trypanothione reductase 2.549e-25 0.31
FSHR_RAT Fshr Follicle-stimulating hormone receptor 4.725e-25 0.31
DPP4_HUMAN DPP4 Dipeptidyl peptidase 4 4.734e-25 0.48
TMPS2_HUMAN TMPRSS2 Transmembrane protease serine 2 9.051e-25 0.40
NMT_YEAST NMT1 Glycylpeptide N-tetradecanoyltransferase 1.777e-24 0.30
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 2.66e-24 0.38
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 9.184e-24 0.46
DEF_STAAU def Peptide deformylase 9.953e-24 0.37
AMP1_PLAFQ M1 family aminopeptidase 1.004e-23 0.32
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 2.143e-23 0.44
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 2.597e-23 0.38
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 6.009e-23 0.32
AMPB_RAT Rnpep Aminopeptidase B 9.239e-23 0.38
MVD1_HUMAN MVD Diphosphomevalonate decarboxylase 1.665e-22 0.28
CTRC_HUMAN CTRC Chymotrypsin-C 2.071e-21 0.37
Q91H74_9FLAV Genome polyprotein 7.337e-21 0.34
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 1.412e-20 0.41
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 1.759e-20 0.31
GNPAT_HUMAN GNPAT Dihydroxyacetone phosphate acyltransferase 4.955e-20 0.32
ELNE_HUMAN ELANE Neutrophil elastase 9.375e-20 0.40
TRYB1_MOUSE Tpsab1 Tryptase 9.753e-20 0.31
PLMN_RAT Plg Plasminogen 2.276e-19 0.38
FNTB_RAT Fntb Protein farnesyltransferase subunit beta 3.044e-19 0.43
KLK5_HUMAN KLK5 Kallikrein-5 3.324e-19 0.33
FNTA_RAT Fnta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 4.291e-19 0.43
CATL1_HUMAN CTSL Cathepsin L1 5.909e-19 0.40
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 9.874e-19 0.33
DPP9_HUMAN DPP9 Dipeptidyl peptidase 9 1.344e-18 0.36
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 2.154e-18 0.31
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 2.89e-18 0.33
ANF_HUMAN NPPA Natriuretic peptides A 3.534e-18 0.36
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 4.659e-18 0.33
MMP1_HUMAN MMP1 Interstitial collagenase 2.873e-17 0.50
LGMN_HUMAN LGMN Legumain 1.11e-16 0.35
O31048_PORGN DPP IV Dipeptidyl peptidase IV 1.11e-16 0.36
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 2.22e-16 0.36
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 3.331e-16 0.40
THRB_RAT F2 Prothrombin 3.331e-16 0.30
FURIN_HUMAN FURIN Furin 4.441e-16 0.41
LY96_HUMAN LY96 Lymphocyte antigen 96 8.882e-16 0.30
FA10_BOVIN F10 Coagulation factor X 1.221e-15 0.41
TRY2_BOVIN Anionic trypsin 1.443e-15 0.41
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 1.554e-15 0.36
B3DH72_DANRE oprd1b Opioid receptor, delta 1b 1.776e-15 0.38
O57585_DANRE oprd1a Opioid receptor homologue 1.776e-15 0.38
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 1.776e-15 0.39
CATG_HUMAN CTSG Cathepsin G 2.109e-15 0.35
ITA2_HUMAN ITGA2 Integrin alpha-2 3.886e-15 0.34
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 4.108e-15 0.43
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 5.551e-15 0.40
CD36_RAT Cd36 Platelet glycoprotein 4 1.144e-14 0.30
MMP2_HUMAN MMP2 72 kDa type IV collagenase 1.976e-14 0.41
NK1R_HUMAN TACR1 Substance-P receptor 2.154e-14 0.38
MC3R_HUMAN MC3R Melanocortin receptor 3 2.32e-14 0.33
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 2.554e-14 0.39
CBPA1_HUMAN CPA1 Carboxypeptidase A1 4.63e-14 0.33
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 5.751e-14 0.34
CATB_HUMAN CTSB Cathepsin B 5.895e-14 0.38
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 1.016e-13 0.29
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.319e-13 0.42
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 1.911e-13 0.39
LKHA4_CAVPO LTA4H Leukotriene A-4 hydrolase 2.622e-13 0.34
OPRX_MOUSE Oprl1 Nociceptin receptor 3.285e-13 0.29
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 3.627e-13 0.37
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 5.479e-13 0.37
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 6.325e-13 0.28
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 6.325e-13 0.28
CCR10_MOUSE Ccr10 C-C chemokine receptor type 10 8.976e-13 0.35
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 1.191e-12 0.32
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 1.69e-12 0.31
SEPR_HUMAN FAP Prolyl endopeptidase FAP 2.874e-12 0.34
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 6.736e-12 0.29
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 6.736e-12 0.29
V2R_PIG AVPR2 Vasopressin V2 receptor 7.435e-12 0.30
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 1.77e-11 0.34
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 2.548e-11 0.36
DPP4_RAT Dpp4 Dipeptidyl peptidase 4 2.986e-11 0.48
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 3.02e-11 0.41
BKRB1_RAT Bdkrb1 B1 bradykinin receptor 3.268e-11 0.44
OPRD_HUMAN OPRD1 Delta-type opioid receptor 3.273e-11 0.40
RENI_HUMAN REN Renin 4.163e-11 0.70
BIRC2_HUMAN BIRC2 Baculoviral IAP repeat-containing protein 2 5.378e-11 0.39
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 7.946e-11 0.29
MCA2_TRYBB MCA2 Metacaspase 8.4e-11 0.32
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 9.198e-11 0.38
TPA_HUMAN PLAT Tissue-type plasminogen activator 9.779e-11 0.41
MMP12_HUMAN MMP12 Macrophage metalloelastase 1.034e-10 0.38
AMPB_HUMAN RNPEP Aminopeptidase B 1.105e-10 0.29
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 1.309e-10 0.43
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 1.541e-10 0.37
ITAV_HUMAN ITGAV Integrin alpha-V 2.107e-10 0.40
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 2.548e-10 0.39
EDNRA_MOUSE Ednra Endothelin-1 receptor 3.326e-10 0.33
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 3.785e-10 0.40
OPRM_MOUSE Oprm1 Mu-type opioid receptor 3.924e-10 0.39
CASPA_HUMAN CASP10 Caspase-10 4.279e-10 0.29
ITB8_HUMAN ITGB8 Integrin beta-8 4.646e-10 0.29
FA10_HUMAN F10 Coagulation factor X 5.176e-10 0.49
AMPL_PIG LAP3 Cytosol aminopeptidase 5.473e-10 0.28
HDA11_HUMAN HDAC11 Histone deacetylase 11 6.859e-10 0.33
CBPB1_HUMAN CPB1 Carboxypeptidase B 1.016e-09 0.36
CATL1_RAT Ctsl Cathepsin L1 1.035e-09 0.29
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 1.868e-09 0.37
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 2.136e-09 0.33
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 2.603e-09 0.31
THER_BACTH npr Thermolysin 2.654e-09 0.52
UROK_HUMAN PLAU Urokinase-type plasminogen activator 3.344e-09 0.39
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 3.808e-09 0.29
MC4R_MOUSE Mc4r Melanocortin receptor 4 9.82e-09 0.33
NTR2_RAT Ntsr2 Neurotensin receptor type 2 1.1e-08 0.34
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 1.135e-08 0.32
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 1.178e-08 0.37
ITB7_HUMAN ITGB7 Integrin beta-7 1.389e-08 0.34
IL2RA_MOUSE Il2ra Interleukin-2 receptor subunit alpha 1.591e-08 0.30
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.735e-08 0.42
CATK_HUMAN CTSK Cathepsin K 1.893e-08 0.38
CBPB1_PIG CPB1 Carboxypeptidase B 2.242e-08 0.35
DCOR_HUMAN ODC1 Ornithine decarboxylase 3.793e-08 0.30
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 4.169e-08 0.33
DLG4_HUMAN DLG4 Disks large homolog 4 4.547e-08 0.29
ITB3_HUMAN ITGB3 Integrin beta-3 4.682e-08 0.40
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 4.982e-08 0.30
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 5.848e-08 0.32
MMP8_HUMAN MMP8 Neutrophil collagenase 5.987e-08 0.41
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 6.192e-08 0.37
V1AR_RAT Avpr1a Vasopressin V1a receptor 6.525e-08 0.34
CYSP_TRYCR Cruzipain 7.603e-08 0.37
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 1.06e-07 0.33
MC5R_MOUSE Mc5r Melanocortin receptor 5 1.21e-07 0.33
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 1.212e-07 0.34
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 1.261e-07 0.40
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 1.332e-07 0.31
FPRS1_MOUSE Fpr-s1 Formyl peptide receptor-related sequence 1 1.384e-07 0.30
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 1.496e-07 0.40
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 1.508e-07 0.32
MC4R_HUMAN MC4R Melanocortin receptor 4 1.64e-07 0.32
CALRL_HUMAN CALCRL Calcitonin gene-related peptide type 1 receptor 1.823e-07 0.32
B4URF0_I33A0 Neuraminidase 3.368e-07 0.35
RIR1_HHV11 RIR1 Ribonucleoside-diphosphate reductase large subunit 3.409e-07 0.33
Q9BRH5_HUMAN DGAT1 DGAT1 protein 3.917e-07 0.30
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 3.922e-07 0.30
MC3R_MOUSE Mc3r Melanocortin receptor 3 4.45e-07 0.31
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 4.811e-07 0.32
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 7.482e-07 0.35
A3EZI9_9HEPC NS3 Genome polyprotein 8.251e-07 0.38
MEN1_HUMAN MEN1 Menin 9.649e-07 0.42
PRIO_MESAU PRNP Major prion protein 1.017e-06 0.31
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 1.031e-06 0.32
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.2e-06 0.39
SEPR_MOUSE Fap Prolyl endopeptidase FAP 1.333e-06 0.34
HDAC6_MOUSE Hdac6 Histone deacetylase 6 1.586e-06 0.35
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 1.611e-06 0.33
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 1.664e-06 0.40
Q82323_9DELA Protease 1.684e-06 0.31
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.943e-06 0.31
CBX7_HUMAN CBX7 Chromobox protein homolog 7 1.982e-06 0.29
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.392e-06 0.31
AMPN_PIG ANPEP Aminopeptidase N 2.534e-06 0.38
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 2.76e-06 0.37
NK3R_RAT Tacr3 Neuromedin-K receptor 2.837e-06 0.31
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 2.982e-06 0.29
KLK7_HUMAN KLK7 Kallikrein-7 3.526e-06 0.33
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 3.628e-06 0.48
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 4.478e-06 0.30
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 4.793e-06 0.31
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 4.838e-06 0.32
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 4.844e-06 0.32
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 5.173e-06 0.46
TGM1_HUMAN TGM1 Protein-glutamine gamma-glutamyltransferase K 5.591e-06 0.33
NRP1_HUMAN NRP1 Neuropilin-1 6.307e-06 0.43
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 6.85e-06 0.37
PAR2_HUMAN F2RL1 Proteinase-activated receptor 2 7.082e-06 0.31
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 7.534e-06 0.34
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 8.282e-06 0.36
MMP10_HUMAN MMP10 Stromelysin-2 8.583e-06 0.38
BLA2_BACCE blm Metallo-beta-lactamase type 2 8.755e-06 0.28
GRAB_HUMAN GZMB Granzyme B 9.25e-06 0.29
Q82134_9DELA prt Protease 9.423e-06 0.31

Sumatriptan

5HT1D_PIG HTR1D 5-hydroxytryptamine receptor 1D 7.016e-201 1.00
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 2.844e-103 1.00
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 1.761e-99 1.00
5HT1B_GORGO HTR1B 5-hydroxytryptamine receptor 1B 1.089e-50 1.00
Q8MI13_BOVIN 5htr1d 5-hydroxytryptamine 1D receptor 4.514e-48 1.00
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 5.062e-37 1.00
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 3.87e-34 1.00
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.43e-32 1.00
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 2.497e-23 1.00
5HT1D_RAT Htr1d 5-hydroxytryptamine receptor 1D 9.821e-20 1.00
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 8.433e-19 1.00
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.22e-15 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 3.686e-13 1.00
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 4.63e-13 1.00
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 6.061e-11 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 8.313e-11 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.146e-09 1.00
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 0.05302 1.00
SYUA_HUMAN SNCA Alpha-synuclein 1.913e-113 0.38
PERM_HUMAN MPO Myeloperoxidase 6.221e-66 0.59
SPRE_HUMAN SPR Sepiapterin reductase 1.892e-60 0.37
NK2R_RAT Tacr2 Substance-K receptor 9.919e-56 0.32
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 9.315e-37 0.41
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.204e-33 0.57
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 9.772e-26 0.57
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 4.632e-23 0.67
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.121e-19 0.45
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 1.665e-15 0.41
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.887e-15 0.37
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 3.053e-14 0.50
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 3.043e-13 0.37
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 5.255e-13 0.38
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 1.835e-12 0.30
CXCR2_RABIT CXCR2 C-X-C chemokine receptor type 2 1.15e-11 0.28
5HT5A_RAT Htr5a 5-hydroxytryptamine receptor 5A 1.119e-10 0.30
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 3.052e-10 0.35
GPR84_HUMAN GPR84 G-protein coupled receptor 84 1.477e-09 0.38
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 2.696e-08 0.29
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 3.967e-07 0.33
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 5.099e-07 0.46
KPYK_STAAR pyk Pyruvate kinase 9.198e-07 0.35
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.455e-06 0.35
AHR_HUMAN AHR Aryl hydrocarbon receptor 1.498e-06 0.30
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 1.851e-06 0.32
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 5.349e-06 0.32
Q9JN24_ECOLX def Peptide deformylase 5.572e-06 0.33
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 6.627e-06 0.33
Q9WTR4_RAT Slc6a2 Transporter 7.645e-06 0.37
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 9.139e-06 0.29

Paroxetine

ARBK1_BOVIN GRK2 Beta-adrenergic receptor kinase 1 5.8e-200 1.00
P2RX4_RAT P2rx4 P2X purinoceptor 4 3.59e-28 1.00
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 1.215e-17 1.00
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 1.144e-14 1.00
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 3.908e-14 1.00
NORA_STAAU norA Quinolone resistance protein NorA 3.375e-10 1.00
Q9WTR4_RAT Slc6a2 Transporter 2.501e-09 1.00
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 6.181e-08 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 4.972e-07 1.00
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 8.86e-07 1.00
PERM_HUMAN MPO Myeloperoxidase 1.137e-05 1.00
Q63380_RAT NET Transporter 1.693e-05 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 1.866e-05 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 3.431e-05 1.00
ARBK1_HUMAN GRK2 Beta-adrenergic receptor kinase 1 0.001146 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.03039 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.0382 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 0.06101 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.196 1.00
NK1R_HUMAN TACR1 Substance-P receptor 0.2894 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.3678 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.3785 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.3999 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.5947 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.6156 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.6272 1.00
GRK5_BOVIN GRK5 G protein-coupled receptor kinase 5 1.098e-51 0.60
EDNRB_PIG EDNRB Endothelin receptor type B 4.735e-31 0.33
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 1.552e-24 0.44
EDNRA_RAT Ednra Endothelin-1 receptor 7.498e-21 0.34
CARP_RHICH Rhizopuspepsin 1.081e-17 0.29
Q5TKS5_STAAU fabI Enoyl-ACP reductase 4.441e-16 0.32
DRD2_MOUSE Drd2 D(2) dopamine receptor 7.316e-14 0.31
LT4R2_HUMAN LTB4R2 Leukotriene B4 receptor 2 4.673e-13 0.28
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 6.306e-13 0.31
5HT6R_RAT Htr6 5-hydroxytryptamine receptor 6 2.564e-09 0.32
EDNRA_HUMAN EDNRA Endothelin-1 receptor 1.767e-08 0.32
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 2.061e-08 0.41
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 6.643e-07 0.34
RENI_HUMAN REN Renin 2.157e-06 0.33
MGLL_HUMAN MGLL Monoglyceride lipase 3.723e-06 0.42
ACHA2_RAT Chrna2 Neuronal acetylcholine receptor subunit alpha-2 4.692e-06 0.30

Moexipril

ACE_HUMAN ACE Angiotensin-converting enzyme 4.855e-153 1.00
ACE_RABIT ACE Angiotensin-converting enzyme 1.74e-108 0.80
ACE_RAT Ace Angiotensin-converting enzyme 8.314e-97 0.64
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.202e-62 0.41
ADAM9_HUMAN ADAM9 Disintegrin and metalloproteinase domain-containing protein 9 1.025e-61 0.34
OPRD_RAT Oprd1 Delta-type opioid receptor 2.244e-61 0.44
OPRM_RAT Oprm1 Mu-type opioid receptor 1.772e-56 0.41
Q9NAW4_PLAFA Cysteine protease falcipain-3 1.034e-52 0.35
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 1.592e-48 0.36
ACE_MOUSE Ace Angiotensin-converting enzyme 3.222e-45 0.51
OPRM_CAVPO OPRM1 Mu-type opioid receptor 2.192e-38 0.38
NEP_RAT Mme Neprilysin 1.729e-36 0.49
DPP4_MOUSE Dpp4 Dipeptidyl peptidase 4 1.002e-35 0.43
CTRB_BOVIN Chymotrypsinogen B 8.794e-35 0.31
XPP2_RAT Xpnpep2 Xaa-Pro aminopeptidase 2 2.176e-32 0.34
NEP_RABIT MME Neprilysin 2.474e-32 0.41
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 5.912e-32 0.33
PRSS8_HUMAN PRSS8 Prostasin 4.541e-29 0.30
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 1.137e-28 0.33
XPP1_HUMAN XPNPEP1 Xaa-Pro aminopeptidase 1 8.534e-28 0.34
XPP2_HUMAN XPNPEP2 Xaa-Pro aminopeptidase 2 1.375e-27 0.34
PRO_HTL1A gag-pro Gag-Pro polyprotein 1.454e-27 0.30
AREG_HUMAN AREG Amphiregulin 5.5e-27 0.30
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 6.898e-26 0.33
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 8.43e-26 0.31
MMP3_HUMAN MMP3 Stromelysin-1 8.821e-25 0.36
CFTR_HUMAN CFTR Cystic fibrosis transmembrane conductance regulator 1.342e-24 0.38
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.583e-24 0.35
Q95PM0_TRYBR rhodesain Cysteine protease 2.494e-24 0.32
Q9NBD4_PLAFA Cysteine protease falcipain-2 8.089e-24 0.29
GHRHR_RAT Ghrhr Growth hormone-releasing hormone receptor 9.442e-24 0.29
OPRD_HUMAN OPRD1 Delta-type opioid receptor 2.728e-23 0.52
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 3.668e-23 0.56
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 1.116e-22 0.51
AGTR2_RAT Agtr2 Type-2 angiotensin II receptor 3.035e-21 0.43
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 2.318e-19 0.30
E1BI31_BOVIN DPP9 Dipeptidyl peptidase 9 3.691e-19 0.30
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 3.809e-18 0.29
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 2.802e-17 0.33
NEP_HUMAN MME Neprilysin 3.492e-17 0.38
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 4.315e-17 0.39
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 4.441e-16 0.35
TPP2_RAT Tpp2 Tripeptidyl-peptidase 2 4.441e-16 0.32
CYSP_TRYCR Cruzipain 7.772e-16 0.31
MMP1_HUMAN MMP1 Interstitial collagenase 7.883e-15 0.34
BRCA1_HUMAN BRCA1 Breast cancer type 1 susceptibility protein 1.366e-14 0.31
PD1L1_HUMAN CD274 Programmed cell death 1 ligand 1 1.843e-14 0.30
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 1.965e-14 0.36
ACES_MOUSE Ache Acetylcholinesterase 2.287e-14 0.32
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 2.709e-14 0.30
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 2.776e-14 0.35
HDAC8_HUMAN HDAC8 Histone deacetylase 8 8.171e-14 0.37
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.279e-13 0.39
FNTB_RAT Fntb Protein farnesyltransferase subunit beta 1.513e-13 0.32
FNTA_RAT Fnta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 1.924e-13 0.32
PP2AA_BOVIN PPP2CA Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 2.074e-13 0.29
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 3.322e-13 0.31
DRD3_RAT Drd3 D(3) dopamine receptor 5.913e-13 0.39
MIP_LEGPN mip Outer membrane protein MIP 6.911e-13 0.29
CCR10_MOUSE Ccr10 C-C chemokine receptor type 10 6.933e-13 0.35
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 7.293e-13 0.30
LKHA4_CAVPO LTA4H Leukotriene A-4 hydrolase 1.02e-12 0.32
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.534e-12 0.32
NR1D1_HUMAN NR1D1 Nuclear receptor subfamily 1 group D member 1 2.764e-12 0.33
AMPN_HUMAN ANPEP Aminopeptidase N 4.09e-12 0.32
BKRB1_RAT Bdkrb1 B1 bradykinin receptor 5.752e-12 0.29
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 7.057e-12 0.34
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 8.289e-12 0.29
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 8.289e-12 0.29
PEPD_HUMAN PEPD Xaa-Pro dipeptidase 8.394e-12 0.29
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 1.537e-11 0.28
CASP8_HUMAN CASP8 Caspase-8 2.286e-11 0.34
CATK_HUMAN CTSK Cathepsin K 2.5e-11 0.33
MC4R_MOUSE Mc4r Melanocortin receptor 4 3.503e-11 0.33
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 3.551e-11 0.30
GLP1R_HUMAN GLP1R Glucagon-like peptide 1 receptor 4.662e-11 0.30
DRD1_BOVIN DRD1 D(1A) dopamine receptor 4.756e-11 0.31
AMPL_HUMAN LAP3 Cytosol aminopeptidase 6.31e-11 0.29
MMP8_HUMAN MMP8 Neutrophil collagenase 6.451e-11 0.32
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 8.682e-11 0.29
SOAT1_HUMAN SOAT1 Sterol O-acyltransferase 1 8.984e-11 0.31
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 9.321e-11 0.35
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 9.585e-11 0.29
CATL1_HUMAN CTSL Cathepsin L1 1.447e-10 0.33
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 2.035e-10 0.29
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 2.177e-10 0.29
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.215e-10 0.46
PPCE_BOVIN PREP Prolyl endopeptidase 2.53e-10 0.33
CASP7_HUMAN CASP7 Caspase-7 2.545e-10 0.34
TF_HUMAN F3 Tissue factor 2.569e-10 0.31
CBPA1_HUMAN CPA1 Carboxypeptidase A1 2.881e-10 0.29
B4URF0_I33A0 Neuraminidase 3.085e-10 0.37
MC5R_MOUSE Mc5r Melanocortin receptor 5 4.939e-10 0.33
BKRB2_RABIT BDKRB2 B2 bradykinin receptor 5.044e-10 0.29
FA7_HUMAN F7 Coagulation factor VII 5.191e-10 0.34
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 6.802e-10 0.29
CATB_HUMAN CTSB Cathepsin B 7.098e-10 0.33
THER_BACTH npr Thermolysin 9.746e-10 0.39
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.003e-09 0.32
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.481e-09 0.30
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 1.818e-09 0.33
OX2R_HUMAN HCRTR2 Orexin receptor type 2 2.23e-09 0.39
NANH_CLOPF nanH Sialidase 3.194e-09 0.35
MC3R_MOUSE Mc3r Melanocortin receptor 3 5.939e-09 0.33
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 6.76e-09 0.31
PPCE_HUMAN PREP Prolyl endopeptidase 1.167e-08 0.33
CATB_BOVIN CTSB Cathepsin B 1.25e-08 0.32
CCR10_HUMAN CCR10 C-C chemokine receptor type 10 1.251e-08 0.35
THRB_BOVIN F2 Prothrombin 1.311e-08 0.36
BIRC2_HUMAN BIRC2 Baculoviral IAP repeat-containing protein 2 2.193e-08 0.30
ANF_HUMAN NPPA Natriuretic peptides A 2.316e-08 0.29
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 2.628e-08 0.30
NRAM_I34A1 Neuraminidase 3.719e-08 0.35
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 3.98e-08 0.41
DLG4_HUMAN DLG4 Disks large homolog 4 4.798e-08 0.29
ACES_HUMAN ACHE Acetylcholinesterase 7.277e-08 0.36
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 8.281e-08 0.34
OX1R_HUMAN HCRTR1 Orexin receptor type 1 9.995e-08 0.39
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 1.136e-07 0.34
MMP2_HUMAN MMP2 72 kDa type IV collagenase 1.325e-07 0.36
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.381e-07 0.28
ACES_BOVIN ACHE Acetylcholinesterase 1.446e-07 0.33
S1PR1_RAT S1pr1 Sphingosine 1-phosphate receptor 1 1.563e-07 0.29
MMP12_HUMAN MMP12 Macrophage metalloelastase 2.455e-07 0.31
CATG_HUMAN CTSG Cathepsin G 2.827e-07 0.31
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 3.842e-07 0.40
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 4.264e-07 0.32
CASP1_HUMAN CASP1 Caspase-1 4.627e-07 0.30
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 7.038e-07 0.32
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 8.254e-07 0.30
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 8.254e-07 0.30
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 8.254e-07 0.30
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 8.254e-07 0.30
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 8.254e-07 0.30
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 8.254e-07 0.30
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 8.254e-07 0.30
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 8.254e-07 0.30
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 8.254e-07 0.30
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 8.254e-07 0.30
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 8.254e-07 0.30
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 8.254e-07 0.30
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 8.254e-07 0.30
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 8.254e-07 0.30
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 8.254e-07 0.30
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 8.254e-07 0.30
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 8.254e-07 0.30
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 8.254e-07 0.30
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.099e-06 0.34
NK1R_RAT Tacr1 Substance-P receptor 1.121e-06 0.30
CHLE_HORSE BCHE Cholinesterase 1.159e-06 0.32
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 1.192e-06 0.34
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.616e-06 0.30
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 1.734e-06 0.31
CASP3_HUMAN CASP3 Caspase-3 2.038e-06 0.34
DPP4_RAT Dpp4 Dipeptidyl peptidase 4 2.122e-06 0.43
RORA_HUMAN RORA Nuclear receptor ROR-alpha 2.515e-06 0.31
NRAM_I77AB Neuraminidase 2.87e-06 0.29
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 3.068e-06 0.32
ACES_ELEEL ache Acetylcholinesterase 3.366e-06 0.33
DPP8_HUMAN DPP8 Dipeptidyl peptidase 8 3.506e-06 0.36
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 4.596e-06 0.29
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 6.832e-06 0.32
APJ_HUMAN APLNR Apelin receptor 9.349e-06 0.29

Latanoprost

PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 3.302e-146 1.00
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 1.367e-129 1.00
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 5.194e-91 0.77
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 1.182e-83 0.77
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 7.586e-58 0.39
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 2.929e-37 0.43
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 2.304e-31 0.39
Q9NAW4_PLAFA Cysteine protease falcipain-3 2.562e-29 0.31
MGLL_RAT Mgll Monoglyceride lipase 1.441e-23 0.32
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 2.06e-23 0.38
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 2.528e-23 0.43
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 8.762e-21 0.32
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 2.152e-18 0.56
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 3.678e-18 0.54
ACE_HUMAN ACE Angiotensin-converting enzyme 1.11e-16 0.30
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 2.998e-15 0.56
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 3.553e-15 0.39
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 2.121e-14 0.40
ACE_RAT Ace Angiotensin-converting enzyme 1.396e-13 0.30
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 3.479e-13 0.39
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 5.641e-13 0.28
TA2R_RAT Tbxa2r Thromboxane A2 receptor 2.242e-12 0.38
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 4.026e-12 0.45
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 4.982e-12 0.38
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 2.796e-11 0.38
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.015e-10 0.30
PI2R_HUMAN PTGIR Prostacyclin receptor 5.319e-10 0.37
PPCE_BOVIN PREP Prolyl endopeptidase 2.494e-09 0.29
RENI_HUMAN REN Renin 3.321e-09 0.33
FDFT_HUMAN FDFT1 Squalene synthase 3.332e-09 0.34
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 4.184e-09 0.30
TLR2_HUMAN TLR2 Toll-like receptor 2 2.543e-08 0.29
CNR1_RAT Cnr1 Cannabinoid receptor 1 2.63e-08 0.42
FDFT_RAT Fdft1 Squalene synthase 3.634e-08 0.32
CATD_BOVIN CTSD Cathepsin D 4.458e-08 0.30
MMP3_HUMAN MMP3 Stromelysin-1 6.295e-08 0.35
MGLL_HUMAN MGLL Monoglyceride lipase 9.431e-08 0.40
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 9.556e-08 0.34
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 1.519e-07 0.38
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 3.244e-07 0.31
CASP1_HUMAN CASP1 Caspase-1 3.574e-07 0.31
ACE_MOUSE Ace Angiotensin-converting enzyme 5.904e-07 0.28
PLM1_PLAFA Plasmepsin-1 8.92e-07 0.31
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 1.683e-06 0.29
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 1.683e-06 0.29
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 1.683e-06 0.29
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 1.683e-06 0.29
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 1.683e-06 0.29
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 1.683e-06 0.29
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 1.683e-06 0.29
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 1.683e-06 0.29
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 1.683e-06 0.29
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 1.683e-06 0.29
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 1.683e-06 0.29
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 1.683e-06 0.29
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 1.683e-06 0.29
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 1.683e-06 0.29
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 1.683e-06 0.29
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 1.683e-06 0.29
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 1.683e-06 0.29
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 1.683e-06 0.29
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 1.74e-06 0.38
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 6.076e-06 0.29

Pirenzepine

ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 4.499e-139 1.00
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 1.877e-124 1.00
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 2.327e-87 1.00
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 6.836e-64 1.00
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 4.63e-30 1.00
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 7.773e-24 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 3.944e-20 1.00
Q8WMX0_BOVIN Muscarinic receptor M1 2.387e-14 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 2.51e-10 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 9.544e-08 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.0001103 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 0.002625 1.00
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 3.528e-64 0.51
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 2.013e-29 0.33
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 2.919e-27 0.34
5HT2B_MOUSE Htr2b 5-hydroxytryptamine receptor 2B 2.274e-25 0.32
5HT6R_MOUSE Htr6 5-hydroxytryptamine receptor 6 4.035e-23 0.28
DRD4_HUMAN DRD4 D(4) dopamine receptor 5.515e-22 0.34
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 1.702e-20 0.38
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 3.49e-20 0.30
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 2.081e-19 0.30
OXYR_MOUSE Oxtr Oxytocin receptor 9.052e-19 0.30
PARP4_HUMAN PARP4 Protein mono-ADP-ribosyltransferase PARP4 1.029e-17 0.29
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 1.11e-16 0.30
G3I1B6_CRIGR 5-hydroxytryptamine receptor 1.11e-16 0.30
5HT1B_CRIGR HTR1B 5-hydroxytryptamine receptor 1B 2.22e-16 0.30
DRD2_HUMAN DRD2 D(2) dopamine receptor 5.551e-16 0.34
KKCC2_HUMAN CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 6.661e-16 0.39
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 1.332e-15 0.39
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 2.331e-15 0.32
DRD3_MOUSE Drd3 D(3) dopamine receptor 3.664e-15 0.29
DRD2_RAT Drd2 D(2) dopamine receptor 9.992e-15 0.41
MK07_HUMAN MAPK7 Mitogen-activated protein kinase 7 1.983e-13 0.38
DRD1_RAT Drd1 D(1A) dopamine receptor 7.744e-13 0.39
5HT2A_MOUSE Htr2a 5-hydroxytryptamine receptor 2A 7.826e-13 0.29
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 2.548e-12 0.37
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 3.808e-12 0.34
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 9.061e-12 0.33
MYLK4_HUMAN MYLK4 Myosin light chain kinase family member 4 9.061e-12 0.33
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 1.945e-11 0.33
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 2.116e-11 0.33
TPP2_RAT Tpp2 Tripeptidyl-peptidase 2 1.494e-10 0.29
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 1.862e-10 0.33
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 2.433e-10 0.33
VGFR2_MOUSE Kdr Vascular endothelial growth factor receptor 2 3.929e-10 0.33
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 6.144e-10 0.34
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 7.432e-10 0.35
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 1.076e-09 0.33
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.495e-09 0.37
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 2.25e-09 0.35
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2.913e-09 0.33
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 2.913e-09 0.33
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 4.592e-09 0.33
PAK3_HUMAN PAK3 Serine/threonine-protein kinase PAK 3 4.592e-09 0.33
5HT2C_MOUSE Htr2c 5-hydroxytryptamine receptor 2C 6.237e-09 0.30
DRD4_RAT Drd4 D(4) dopamine receptor 8.804e-09 0.31
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 1.061e-08 0.33
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 1.061e-08 0.33
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 1.106e-08 0.33
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 1.106e-08 0.33
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 1.106e-08 0.33
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1.106e-08 0.33
KAPCB_HUMAN PRKACB cAMP-dependent protein kinase catalytic subunit beta 1.181e-08 0.29
STK16_HUMAN STK16 Serine/threonine-protein kinase 16 1.562e-08 0.33
AL3A1_HUMAN ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 2.254e-08 0.37
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 2.256e-08 0.33
MYO3B_HUMAN MYO3B Myosin-IIIb 2.84e-08 0.33
STK26_HUMAN STK26 Serine/threonine-protein kinase 26 3.2e-08 0.33
TLK2_HUMAN TLK2 Serine/threonine-protein kinase tousled-like 2 3.585e-08 0.29
M4K1_HUMAN MAP4K1 Mitogen-activated protein kinase kinase kinase kinase 1 4.465e-08 0.33
HRH1_RAT Hrh1 Histamine H1 receptor 4.661e-08 0.32
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 5.167e-08 0.34
CDK16_HUMAN CDK16 Cyclin-dependent kinase 16 6.136e-08 0.33
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 6.519e-08 0.33
SRPK2_HUMAN SRPK2 SRSF protein kinase 2 6.519e-08 0.33
STK11_HUMAN STK11 Serine/threonine-protein kinase STK11 6.519e-08 0.33
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 8.315e-08 0.33
PRP4B_HUMAN PRPF4B Serine/threonine-protein kinase PRP4 homolog 1.365e-07 0.33
HIPK1_HUMAN HIPK1 Homeodomain-interacting protein kinase 1 1.92e-07 0.33
VGFR1_MOUSE Flt1 Vascular endothelial growth factor receptor 1 2.378e-07 0.29
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 2.648e-07 0.33
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 2.648e-07 0.33
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 3.033e-07 0.36
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 3.074e-07 0.37
AAK1_HUMAN AAK1 AP2-associated protein kinase 1 4.024e-07 0.33
PI51C_HUMAN PIP5K1C Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma 4.481e-07 0.29
TLK1_HUMAN TLK1 Serine/threonine-protein kinase tousled-like 1 4.481e-07 0.29
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 4.816e-07 0.33
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 4.816e-07 0.33
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 4.816e-07 0.33
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 4.816e-07 0.33
KC1A_PIG CSNK1A1 Casein kinase I isoform alpha 5.464e-07 0.28
TYTR_TRYCR TPR Trypanothione reductase 7.272e-07 0.31
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 8.292e-07 0.33
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 9.112e-07 0.29
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 1.112e-06 0.36
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 1.177e-06 0.30
INSRR_HUMAN INSRR Insulin receptor-related protein 1.362e-06 0.33
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 1.362e-06 0.33
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 1.411e-06 0.33
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 1.549e-06 0.29
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 1.809e-06 0.29
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 2.147e-06 0.33
PI42B_HUMAN PIP4K2B Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 2.147e-06 0.33
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 2.332e-06 0.33
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 2.413e-06 0.30
PDE2A_HUMAN PDE2A cGMP-dependent 3',5'-cyclic phosphodiesterase 2.508e-06 0.32
PLK4_HUMAN PLK4 Serine/threonine-protein kinase PLK4 3.087e-06 0.36
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 3.267e-06 0.33
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 3.267e-06 0.33
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 3.723e-06 0.33
HRH4_HUMAN HRH4 Histamine H4 receptor 4.761e-06 0.32
MARK1_HUMAN MARK1 Serine/threonine-protein kinase MARK1 4.816e-06 0.33
PAK5_HUMAN PAK5 Serine/threonine-protein kinase PAK 5 4.816e-06 0.33
PI51A_HUMAN PIP5K1A Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 4.816e-06 0.33
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 4.816e-06 0.33
B2LUN4_PIG GSK3-beta Glycogen synthase kinase 3 beta 5.037e-06 0.28
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 5.338e-06 0.33
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 6.172e-06 0.33
DRD1_HUMAN DRD1 D(1A) dopamine receptor 6.308e-06 0.35
DRD4_MOUSE Drd4 D(4) dopamine receptor 6.605e-06 0.29
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 6.907e-06 0.33
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 6.907e-06 0.33
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 7.112e-06 0.29
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 8.893e-06 0.31
DRD3_HUMAN DRD3 D(3) dopamine receptor 9.058e-06 0.35
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 9.664e-06 0.33
RIOK1_HUMAN RIOK1 Serine/threonine-protein kinase RIO1 9.664e-06 0.33
RIOK3_HUMAN RIOK3 Serine/threonine-protein kinase RIO3 9.664e-06 0.33
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 9.664e-06 0.33

Leucovorin

SO1A3_RAT Slco1a3 Solute carrier organic anion transporter family member 1A3 2.15e-134 1.00
DYR_HUMAN DHFR Dihydrofolate reductase 2.069e-78 1.00
PUR2_HUMAN GART Trifunctional purine biosynthetic protein adenosine-3 3.723e-230 0.59
TYSY_MOUSE Tyms Thymidylate synthase 1.385e-193 0.59
PUR2_MOUSE Gart Trifunctional purine biosynthetic protein adenosine-3 1.828e-160 0.59
FOLR1_HUMAN FOLR1 Folate receptor alpha 6.246e-142 0.46
FOLC_HUMAN FPGS Folylpolyglutamate synthase, mitochondrial 1.216e-131 0.57
DYR_MOUSE Dhfr Dihydrofolate reductase 4.073e-130 0.51
PCFT_HUMAN SLC46A1 Proton-coupled folate transporter 4.236e-129 0.46
TYSY_HUMAN TYMS Thymidylate synthase 1.004e-121 0.55
FOLC_MOUSE Fpgs Folylpolyglutamate synthase, mitochondrial 5.463e-116 0.59
DYR_ENTFC folA Dihydrofolate reductase 2.256e-111 0.47
FOLR2_HUMAN FOLR2 Folate receptor beta 1.159e-110 0.46
S19A1_HUMAN SLC19A1 Reduced folate transporter 2.728e-91 0.46
DYR_LACCA folA Dihydrofolate reductase 1.231e-85 0.60
METH_HUMAN MTR Methionine synthase 1.074e-79 0.47
MTDC_HUMAN MTHFD2 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial 8.218e-77 0.62
E2QDN0_ECOLX thyA Thymidylate synthase 8.306e-74 0.49
FOLC_ECOLI folC Dihydrofolate synthase/folylpolyglutamate synthase 1.197e-73 0.59
TYSY_RAT Tyms Thymidylate synthase 3.643e-67 0.42
TYSY_LACCA thyA Thymidylate synthase 3.277e-54 0.47
PH4H_RAT Pah Phenylalanine-4-hydroxylase 3.464e-37 0.32
C3SWJ7_ECOLX thyA Thymidylate synthase 2.098e-33 0.63
DYR_RAT Dhfr Dihydrofolate reductase 6.601e-30 0.53
HMGB1_HUMAN HMGB1 High mobility group protein B1 1.397e-27 0.34
Q9I056_PSEAE cpg2 Carboxypeptidase G2 1.279e-26 0.30
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 3.172e-26 0.69
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 9.711e-25 0.53
DRTS_TOXGO Bifunctional dihydrofolate reductase-thymidylate synthase 2.804e-19 0.53
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 4.014e-17 0.33
DHPS_ECOLI folP Dihydropteroate synthase 1.221e-15 0.33
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 3.438e-13 0.35
DYR_CHICK DHFR Dihydrofolate reductase 6.154e-13 0.46
DYR_MYCTU folA Dihydrofolate reductase 1.39e-12 0.34
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 1.248e-11 0.31
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 6.174e-11 0.31
DYR_PNECA Dihydrofolate reductase 4.541e-10 0.43
Q81R22_BACAN dfrA Dihydrofolate reductase 6.84e-10 0.35
TYSY_ECOLI thyA Thymidylate synthase 1.319e-08 0.42
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 5.838e-08 0.47
DRTS_LEIMA Bifunctional dihydrofolate reductase-thymidylate synthase 4.339e-07 0.34
DYR_BOVIN DHFR Dihydrofolate reductase 1.549e-06 0.34
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 2.284e-06 0.31
X5EH84_STAAU folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 7.298e-06 0.30

Estrone

CP19A_HUMAN CYP19A1 Aromatase 2.421e-134 1.00
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 6.372e-96 1.00
SHBG_HUMAN SHBG Sex hormone-binding globulin 4.715e-64 1.00
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 5.249e-61 1.00
ESR1_HUMAN ESR1 Estrogen receptor 5.282e-38 1.00
Q690N0_BOVIN PGR Progesterone receptor 1.395e-35 1.00
ESR2_HUMAN ESR2 Estrogen receptor beta 6.828e-35 1.00
ANDR_RAT Ar Androgen receptor 1.743e-14 1.00
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 1.716e-08 1.00
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 0.0297 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.239 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.4773 1.00
STS_HUMAN STS Steryl-sulfatase 1.738e-176 0.68
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 3.942e-88 0.70
ST1E1_BOVIN SULT1E1 Sulfotransferase 1E1 8.959e-72 0.54
Q95MF8_PIG Sulfotransferase 3.315e-70 0.40
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 9.215e-63 0.41
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.187e-46 0.41
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 7.332e-45 0.61
S22A8_RAT Slc22a8 Solute carrier family 22 member 8 5.761e-43 0.70
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.876e-38 0.62
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 2.731e-35 0.53
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 1.445e-29 0.38
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 4.294e-28 0.45
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.853e-26 0.38
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 2.979e-26 0.44
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 2.228e-25 0.41
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 1.021e-24 0.62
CP24A_RAT Cyp24a1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1.289e-24 0.33
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 2.172e-23 0.70
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 3.931e-23 0.37
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 8.369e-21 0.43
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 2.472e-19 0.62
ESR1_MOUSE Esr1 Estrogen receptor 3.978e-19 0.62
ESR2_MOUSE Esr2 Estrogen receptor beta 3.978e-19 0.62
BCL9_HUMAN BCL9 B-cell CLL/lymphoma 9 protein 5.41e-19 0.30
ADCY5_RAT Adcy5 Adenylate cyclase type 5 6.58e-19 0.36
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.248e-18 0.62
AT12A_HUMAN ATP12A Potassium-transporting ATPase alpha chain 2 1.887e-15 0.32
MMP26_HUMAN MMP26 Matrix metalloproteinase-26 3.442e-14 0.29
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 2.101e-13 0.43
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 2.566e-13 0.29
ESR1_RAT Esr1 Estrogen receptor 4.398e-13 0.62
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 7.461e-13 0.62
ERG2_YEAST ERG2 C-8 sterol isomerase 8.997e-12 0.33
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 3.288e-11 0.29
ERR1_HUMAN ESRRA Steroid hormone receptor ERR1 1.302e-10 0.62
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 8.021e-10 0.36
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 3.005e-09 0.36
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 3.598e-09 0.29
GCR_HUMAN NR3C1 Glucocorticoid receptor 1.02e-08 0.47
OPRM_BOVIN OPRM1 Mu-type opioid receptor 2.446e-08 0.30
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.631e-08 0.76
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 6.611e-08 0.32
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 1.732e-07 0.70
ESR2_RAT Esr2 Estrogen receptor beta 1.84e-07 0.62
C11B2_RAT Cyp11b2 Cytochrome P450 11B2, mitochondrial 1.848e-07 0.33
OPRM_RAT Oprm1 Mu-type opioid receptor 1.86e-07 0.32
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.362e-07 0.29
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.079e-06 0.35
OPRD_HUMAN OPRD1 Delta-type opioid receptor 2.2e-06 0.35
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 2.354e-06 0.29
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 2.71e-06 0.38
NR1I2_HUMAN NR1I2 Nuclear receptor subfamily 1 group I member 2 2.868e-06 0.30
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 4.635e-06 0.35
DRD2_BOVIN DRD2 D(2) dopamine receptor 5.95e-06 0.31

Ibandronate

FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 6.187e-120 1.00
FDFT_RAT Fdft1 Squalene synthase 0.01897 1.00
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 1.573e-101 0.63
Q197X6_TOXGO FPPS Farnesyl diphosphate synthase 1.698e-81 0.46
Q8WS26_TRYCR Farnesyl diphosphate synthase 1.798e-56 0.61
GGPPS_HUMAN GGPS1 Geranylgeranyl pyrophosphate synthase 4.749e-52 0.61
Q964Q8_TRYCR SPPS Solanesyl diphosphate synthase 6.54e-40 0.29
ISPA_ECOLI ispA Farnesyl diphosphate synthase 1.124e-26 0.60
ALF_CANAL FBA1 Fructose-bisphosphate aldolase 1.4e-24 0.31
A85C_MYCTU fbpC Diacylglycerol acyltransferase/mycolyltransferase Ag85C 1.769e-22 0.34
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 1.11e-16 0.42
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 1.11e-16 0.61
B1LRJ1_ECOSM traI Type IV secretion-like conjugative transfer relaxase protein TraI 7.438e-15 0.28
Q8ST54_TRYCR HK Phosphotransferase 4.307e-13 0.61
EST2C_MOUSE Ces2c Acylcarnitine hydrolase 1.339e-11 0.28
KDM5A_HUMAN KDM5A Lysine-specific demethylase 5A 8.302e-11 0.39
PGK_YEAST PGK1 Phosphoglycerate kinase 1.479e-10 0.28
A1ZA98_DROME Jhe Carboxylic ester hydrolase 4.608e-09 0.28
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 6.437e-09 0.33
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 3.127e-08 0.39
AMPL_HUMAN LAP3 Cytosol aminopeptidase 4.619e-08 0.32
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 6.469e-07 0.61

Apomorphine

DRD1_RAT Drd1 D(1A) dopamine receptor 2.289e-119 1.00
DRD1_MOUSE Drd1 D(1A) dopamine receptor 1.544e-89 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.412e-67 1.00
DRD2_RAT Drd2 D(2) dopamine receptor 5.903e-55 1.00
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 2.979e-34 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 3.566e-29 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 7.774e-24 1.00
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.245e-21 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 4.617e-12 1.00
DRD3_RAT Drd3 D(3) dopamine receptor 9.742e-12 1.00
MEX5_CAEEL mex-5 Zinc finger protein mex-5 3.891e-11 1.00
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 4.52e-11 1.00
Q9BHT9_PLABE G6PD-6PGL Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 2.281e-09 1.00
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.212e-07 1.00
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 1.556e-06 1.00
DRD4_RAT Drd4 D(4) dopamine receptor 3.343e-05 1.00
DRD2_BOVIN DRD2 D(2) dopamine receptor 3.431e-05 1.00
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 0.03006 1.00
MDM2_HUMAN MDM2 E3 ubiquitin-protein ligase Mdm2 0.1953 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9986 1.00
TY3H_HUMAN TH Tyrosine 3-monooxygenase 1.353e-88 0.73
DRD5_HUMAN DRD5 D(1B) dopamine receptor 4.615e-44 0.36
ACHA2_HUMAN CHRNA2 Neuronal acetylcholine receptor subunit alpha-2 9.376e-19 0.30
G5EF15_CAEEL pos-1 Cytoplasmic zinc-finger protein 5.185e-11 0.73
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 1.517e-10 0.31
PARP4_HUMAN PARP4 Protein mono-ADP-ribosyltransferase PARP4 2.72e-09 0.29
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 1.218e-08 0.35
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 1.491e-08 0.35
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 5.082e-08 0.57
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 2.555e-06 0.46
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 2.703e-06 0.45

Pentazocine

OPRK_CAVPO OPRK1 Kappa-type opioid receptor 4.704e-118 1.00
OPRM_RAT Oprm1 Mu-type opioid receptor 1.145e-82 1.00
OPRD_HUMAN OPRD1 Delta-type opioid receptor 1.495e-80 1.00
ZN664_CAVPO ZNF664 Zinc finger protein 664 2.714e-79 1.00
OPRM_CAVPO OPRM1 Mu-type opioid receptor 3.141e-68 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 2.318e-62 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.417e-61 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.514e-46 1.00
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.898e-40 1.00
ERG2_YEAST ERG2 C-8 sterol isomerase 2.593e-22 1.00
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 5.247e-19 1.00
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 1.584e-11 1.00
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 0.000728 1.00
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 0.07089 1.00
F7HEV7_MACMU YTHDF2 G_PROTEIN_RECEP_F1_2 domain-containing protein 2.749e-151 0.79
H9FL65_MACMU OPRK1 Kappa-type opioid receptor 2.749e-151 0.79
OPRM_MACMU OPRM1 Mu-type opioid receptor 2.252e-134 0.79
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 2.315e-128 0.70
OPRM_MOUSE Oprm1 Mu-type opioid receptor 9.77e-55 0.71
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 3.03e-41 0.71
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 2.257e-40 0.71
OPRM_BOVIN OPRM1 Mu-type opioid receptor 7.454e-36 0.34
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.299e-33 0.71
OPRD_RAT Oprd1 Delta-type opioid receptor 1.747e-25 0.66
OPRK_RAT Oprk1 Kappa-type opioid receptor 9.809e-11 0.38
ESR1_HUMAN ESR1 Estrogen receptor 6.346e-07 0.32
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 7.95e-07 0.34
DRD5_HUMAN DRD5 D(1B) dopamine receptor 9.71e-07 0.30
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 2.02e-06 0.34

Daunorubicin

S10A4_HUMAN S100A4 Protein S100-A4 5.525e-104 1.00
1433G_HUMAN YWHAG 14-3-3 protein gamma 4.48e-49 1.00
O40947_HHV8 ORF 73 2.985e-30 1.00
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 3.481e-09 1.00
PAX8_HUMAN PAX8 Paired box protein Pax-8 6.004e-07 1.00
MMP2_HUMAN MMP2 72 kDa type IV collagenase 0.01765 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.2687 1.00
FANCF_HUMAN FANCF Fanconi anemia group F protein 1.14e-67 0.54
CHIO_HUMAN CHN2 Beta-chimaerin 1.414e-62 0.50
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 1.466e-48 0.88
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 4.396e-22 0.88
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 4.441e-16 0.88
LOX12_MOUSE Alox12 Arachidonate 12-lipoxygenase, 12S-type 5.44e-15 0.28
CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 4.705e-08 0.88
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 2.618e-06 0.88

Aprepitant

NK1R_HUMAN TACR1 Substance-P receptor 9.33e-104 1.00
NK1R_MERUN TACR1 Substance-P receptor 1.311e-09 1.00
NK3R_HUMAN TACR3 Neuromedin-K receptor 1.071e-05 1.00
NK1R_RAT Tacr1 Substance-P receptor 3.754e-20 0.68
B2RXC2_MOUSE Itpkb Kinase 5.718e-10 0.29
CETP_HUMAN CETP Cholesteryl ester transfer protein 1.476e-09 0.32
NR1I2_HUMAN NR1I2 Nuclear receptor subfamily 1 group I member 2 1.164e-08 0.45
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 1.139e-06 0.34

Azatadine

HRH1_RAT Hrh1 Histamine H1 receptor 1.831e-103 1.00
S6A15_HUMAN SLC6A15 Sodium-dependent neutral amino acid transporter B(0)AT2 1.95e-134 0.49
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 7.414e-39 0.49
DRD5_HUMAN DRD5 D(1B) dopamine receptor 3.96e-33 0.38
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 4.697e-33 0.51
HRH4_HUMAN HRH4 Histamine H4 receptor 2.177e-24 0.42
IMA1_HUMAN KPNA2 Importin subunit alpha-1 5.245e-24 0.30
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 1.44e-23 0.51
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 1.434e-20 0.74
DRD1_RAT Drd1 D(1A) dopamine receptor 4.707e-18 0.38
5HT3B_HUMAN HTR3B 5-hydroxytryptamine receptor 3B 8.338e-18 0.34
MSRA_BOVIN MSRA Mitochondrial peptide methionine sulfoxide reductase 4.899e-17 0.33
HRH4_RAT Hrh4 Histamine H4 receptor 8.882e-16 0.42
HRH1_HUMAN HRH1 Histamine H1 receptor 1.11e-15 0.55
DRD1_HUMAN DRD1 D(1A) dopamine receptor 6.328e-15 0.49
5HT2C_MOUSE Htr2c 5-hydroxytryptamine receptor 2C 3.852e-14 0.49
RLGM1_TRYBB REL1 RNA-editing ligase 1, mitochondrial 3.049e-13 0.33
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 1.333e-12 0.38
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.406e-10 0.69
PADI1_HUMAN PADI1 Protein-arginine deiminase type-1 4.884e-10 0.29
PADI2_HUMAN PADI2 Protein-arginine deiminase type-2 4.884e-10 0.29
PADI3_HUMAN PADI3 Protein-arginine deiminase type-3 4.884e-10 0.29
HRH2_HUMAN HRH2 Histamine H2 receptor 1.093e-09 0.50
DRD4_HUMAN DRD4 D(4) dopamine receptor 4.87e-09 0.38
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 5.997e-09 0.49
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.283e-08 0.31
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.6e-08 0.38
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 4.372e-08 0.32
KMT5A_HUMAN KMT5A N-lysine methyltransferase KMT5A 4.633e-08 0.30
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 5.002e-08 0.49
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 6.808e-08 0.50
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 7.343e-08 0.36
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 8.355e-08 0.36
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 4.613e-07 0.49
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 4.955e-07 0.50
CP19A_RAT Cyp19a1 Aromatase 5.427e-07 0.32
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 7.045e-07 0.29
MGLL_HUMAN MGLL Monoglyceride lipase 9.851e-07 0.47
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.923e-06 0.50
DRD2_RAT Drd2 D(2) dopamine receptor 2.215e-06 0.49
DRD3_HUMAN DRD3 D(3) dopamine receptor 2.381e-06 0.50
HRH1_CAVPO HRH1 Histamine H1 receptor 3.09e-06 0.49
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 4.559e-06 0.33
DRD2_HUMAN DRD2 D(2) dopamine receptor 6.139e-06 0.56
ABHD6_HUMAN ABHD6 Monoacylglycerol lipase ABHD6 6.446e-06 0.44
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 8.922e-06 0.49

Clodronic_acid

B1LRJ1_ECOSM traI Type IV secretion-like conjugative transfer relaxase protein TraI 2.093e-99 1.00
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 9.993e-08 0.32
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 1.159e-06 0.30

Simvastatin

HMDH_RAT Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.875e-97 1.00
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 2.07e-40 1.00
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.836e-32 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.2687 1.00
CHLE_HORSE BCHE Cholinesterase 0.6331 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.7549 1.00
ACES_ELEEL ache Acetylcholinesterase 0.9235 1.00
CAC1C_MOUSE Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 2.309e-48 0.61
ITB2_HUMAN ITGB2 Integrin beta-2 2.22e-16 0.47
ITAL_HUMAN ITGAL Integrin alpha-L 5.074e-14 0.47
ICAM1_HUMAN ICAM1 Intercellular adhesion molecule 1 5.497e-11 0.47

Tobramycin

Q77YF8_HV1H2 rev Protein Rev 1.709e-93 1.00
CXB2_HUMAN GJB2 Gap junction beta-2 protein 3.18e-96 0.77
LEG4_HUMAN LGALS4 Galectin-4 4.303e-62 0.37
LEG8_HUMAN LGALS8 Galectin-8 4.303e-62 0.37
FGF1_HUMAN FGF1 Fibroblast growth factor 1 2.696e-34 0.33
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 3.58e-23 0.29
FGF2_HUMAN FGF2 Fibroblast growth factor 2 3.317e-21 0.33
FABH_ECOLI fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 4.193e-21 0.77
AMYP_HUMAN AMY2A Pancreatic alpha-amylase 6.741e-19 0.30
TYRO_HUMAN TYR Tyrosinase 2.411e-17 0.30
B4EH87_BURCJ Lectin 2.22e-16 0.31
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 1.665e-15 0.33
AMY1A_HUMAN AMY1A Alpha-amylase 1 2.776e-15 0.29
LEG3_HUMAN LGALS3 Galectin-3 1.266e-14 0.37
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.827e-13 0.76
P94451_GEOSE Alpha-amylase 2.601e-13 0.29
TAT_HV112 tat Protein Tat 4.454e-13 0.31
LEF_BACAN lef Lethal factor 4.726e-13 0.54
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 3.138e-10 0.31
LEG9_HUMAN LGALS9 Galectin-9 8.676e-07 0.30

Norethisterone

Q690N0_BOVIN PGR Progesterone receptor 4.109e-90 1.00
SHBG_HUMAN SHBG Sex hormone-binding globulin 2.293e-87 1.00
ANDR_RAT Ar Androgen receptor 4.382e-36 1.00
PRGR_HUMAN PGR Progesterone receptor 8.934e-27 1.00
GCR_HUMAN NR3C1 Glucocorticoid receptor 6.863e-22 1.00
ESR1_HUMAN ESR1 Estrogen receptor 1.63e-08 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.02072 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.2326 1.00
PRGR_RAT Pgr Progesterone receptor 4.099e-71 0.67
F1Q298_CANLF NR3C1 Glucocorticoid receptor 1.646e-60 0.44
GCR_PIG NR3C1 Glucocorticoid receptor 1.646e-60 0.44
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 2.052e-56 0.41
STS_HUMAN STS Steryl-sulfatase 6.455e-35 0.36
PRGR_RABIT PGR Progesterone receptor 1.534e-28 0.66
CP19A_HUMAN CYP19A1 Aromatase 6.321e-27 0.57
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.761e-26 0.35
SHBG_RAT Shbg Sex hormone-binding globulin 3.343e-26 0.32
ANDR_HUMAN AR Androgen receptor 1.644e-20 0.59
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 6e-20 0.32
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.985e-19 0.31
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.327e-19 0.32
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 2.22e-16 0.37
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.442e-15 0.32
MCR_HUMAN NR3C2 Mineralocorticoid receptor 6.439e-14 0.59
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 4.377e-12 0.37
GCR_RAT Nr3c1 Glucocorticoid receptor 5.156e-12 0.44
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 8.026e-12 0.31
ANDR_MOUSE Ar Androgen receptor 1.646e-10 0.34
GLNA_HUMAN GLUL Glutamine synthetase 7.039e-10 0.31
PPO2_AGABI PPO2 Polyphenol oxidase 2 8.499e-09 0.64
ERG2_YEAST ERG2 C-8 sterol isomerase 1.152e-08 0.34
IL6_HUMAN IL6 Interleukin-6 6.548e-08 0.31
NK1R_RAT Tacr1 Substance-P receptor 1.393e-07 0.35
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 5.385e-07 0.32
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.801e-06 0.30
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 3.299e-06 0.29
VP16_HHV11 Tegument protein VP16 3.575e-06 0.34

Flurbiprofen

PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.267e-60 1.00
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 1.682e-58 1.00
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 9.538e-42 1.00
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.211e-38 1.00
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 2.42e-19 1.00
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 8.568e-18 1.00
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 4.869e-10 1.00
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 0.001086 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.01248 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.08147 1.00
NEP_MOUSE Mme Neprilysin 1.102e-51 0.31
3BHS2_HUMAN HSD3B2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 5.166e-42 0.33
LPH_HUMAN LCT Lactase-phlorizin hydrolase 1.28e-40 0.32
AMPB_MOUSE Rnpep Aminopeptidase B 7.528e-39 0.31
AMPL_BOVIN LAP3 Cytosol aminopeptidase 7.528e-39 0.31
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 4.064e-38 0.47
KYNU_RAT Kynu Kynureninase 7.142e-37 0.29
HAOX2_HUMAN HAO2 Hydroxyacid oxidase 2 8.333e-36 0.28
ACE_MOUSE Ace Angiotensin-converting enzyme 8.703e-34 0.31
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.836e-32 0.47
BLAB_BACCE Metallo-beta-lactamase type 2 9.005e-29 0.32
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.524e-25 0.34
AL5AP_HUMAN ALOX5AP Arachidonate 5-lipoxygenase-activating protein 1.515e-23 0.36
PD2R2_RAT Ptgdr2 Prostaglandin D2 receptor 2 7.04e-23 0.28
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 9.929e-23 0.33
HELD_ECOLI helD DNA helicase IV 8.99e-22 0.42
NEP_PIG MME Neprilysin 1.093e-19 0.31
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 2.322e-19 0.31
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 3.691e-19 0.30
MENB_MYCTU menB 1,4-dihydroxy-2-naphthoyl-CoA synthase 3.719e-19 0.29
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 6.422e-19 0.31
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 6.741e-19 0.30
KCNQ2_MOUSE Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 4.117e-18 0.30
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 4.666e-18 0.40
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 5.637e-18 0.59
NEP_RAT Mme Neprilysin 1.261e-17 0.32
NEP_HUMAN MME Neprilysin 1.811e-17 0.31
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 3.059e-17 0.34
IL8_HUMAN CXCL8 Interleukin-8 3.355e-17 0.47
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 1.11e-16 0.31
KCNN4_HUMAN KCNN4 Intermediate conductance calcium-activated potassium channel protein 4 4.441e-16 0.31
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 1.221e-15 0.30
VIPR1_RAT Vipr1 Vasoactive intestinal polypeptide receptor 1 1.332e-15 0.31
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 2.22e-15 0.29
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 1.088e-14 0.41
GBA2_HUMAN GBA2 Non-lysosomal glucosylceramidase 1.577e-14 0.34
CEGT_HUMAN UGCG Ceramide glucosyltransferase 6.406e-14 0.34
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 7.561e-14 0.30
FDFT_HUMAN FDFT1 Squalene synthase 7.96e-14 0.47
CBPA1_HUMAN CPA1 Carboxypeptidase A1 8.005e-14 0.31
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.801e-13 0.40
KYNU_HUMAN KYNU Kynureninase 2.173e-13 0.29
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 2.173e-13 0.29
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 3.093e-13 0.33
GRIA4_HUMAN GRIA4 Glutamate receptor 4 3.899e-13 0.36
ADA12_HUMAN ADAM12 Disintegrin and metalloproteinase domain-containing protein 12 3.922e-13 0.29
SUIS_HUMAN SI Sucrase-isomaltase, intestinal 6.098e-13 0.34
AMPX_VIBPR Bacterial leucyl aminopeptidase 1.4e-12 0.31
SC6A5_RAT Slc6a5 Sodium- and chloride-dependent glycine transporter 2 1.498e-12 0.34
BLA2_BACCE blm Metallo-beta-lactamase type 2 7.7e-12 0.32
PPGB_HUMAN CTSA Lysosomal protective protein 1.855e-11 0.34
AMPN_MOUSE Anpep Aminopeptidase N 1.92e-11 0.31
Q6DMN0_TOXGO CPL Cathepsin L 4.084e-10 0.29
GALR1_RAT Galr1 Galanin receptor type 1 4.398e-10 0.29
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 4.556e-10 0.37
NEP_RABIT MME Neprilysin 5.909e-10 0.31
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 6.96e-10 0.33
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 8.968e-10 0.38
ACE_HUMAN ACE Angiotensin-converting enzyme 1.247e-09 0.31
DGAT1_RAT Dgat1 Diacylglycerol O-acyltransferase 1 1.4e-09 0.44
HMDH_RAT Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 4.01e-09 0.32
CATK_HUMAN CTSK Cathepsin K 4.17e-09 0.41
CATL1_HUMAN CTSL Cathepsin L1 4.373e-09 0.41
MMP8_RAT Mmp8 Neutrophil collagenase 5.048e-09 0.28
MGA_HUMAN MGAM Maltase-glucoamylase, intestinal 6.91e-09 0.34
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 7.778e-09 0.29
ALBU_BOVIN ALB Serum albumin 8.387e-09 0.40
CATB_HUMAN CTSB Cathepsin B 1.413e-08 0.41
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 1.53e-08 0.29
CBPA1_BOVIN CPA1 Carboxypeptidase A1 1.55e-08 0.33
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.652e-08 0.37
PGH2_BOVIN PTGS2 Prostaglandin G/H synthase 2 1.744e-08 0.40
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 2.552e-08 0.48
CHLE_HORSE BCHE Cholinesterase 2.573e-08 0.45
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 3.301e-08 0.29
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 4.463e-08 0.32
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 6.103e-08 0.36
SC6A9_RAT Slc6a9 Sodium- and chloride-dependent glycine transporter 1 6.908e-08 0.34
Q8ST54_TRYCR HK Phosphotransferase 7.031e-08 0.35
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 8.323e-08 0.32
P2Y14_MOUSE P2ry14 P2Y purinoceptor 14 8.564e-08 0.29
AMPN_PIG ANPEP Aminopeptidase N 1.192e-07 0.32
AMPB_RAT Rnpep Aminopeptidase B 1.612e-07 0.31
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 1.612e-07 0.31
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 1.863e-07 0.33
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 2.221e-07 0.32
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 2.993e-07 0.30
PD1L1_HUMAN CD274 Programmed cell death 1 ligand 1 2.994e-07 0.28
GLCM_HUMAN GBA Lysosomal acid glucosylceramidase 3.03e-07 0.34
CATS_HUMAN CTSS Cathepsin S 3.182e-07 0.41
PGES2_HUMAN PTGES2 Prostaglandin E synthase 2 4.568e-07 0.35
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 4.919e-07 0.32
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 5.029e-07 0.33
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 5.217e-07 0.30
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 5.906e-07 0.36
PDK2_HUMAN PDK2 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 6.065e-07 0.35
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.109e-06 0.30
Q56D28_CAVPO CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells 1.198e-06 0.28
IF4E_HUMAN EIF4E Eukaryotic translation initiation factor 4E 1.261e-06 0.29
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 1.497e-06 0.40
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 1.959e-06 0.29
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 1.993e-06 0.32
PD2R2_MOUSE Ptgdr2 Prostaglandin D2 receptor 2 2.124e-06 0.28
GPR88_HUMAN GPR88 Probable G-protein coupled receptor 88 2.735e-06 0.31
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 3.103e-06 0.38
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 3.213e-06 0.28
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 3.667e-06 0.32
CATK_RABIT CTSK Cathepsin K 3.723e-06 0.31
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 3.736e-06 0.40
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 4.296e-06 0.30
ACES_ELEEL ache Acetylcholinesterase 4.323e-06 0.45
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 5.603e-06 0.29
AMP1_PLAFQ M1 family aminopeptidase 7.89e-06 0.31
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 8.851e-06 0.36
MMP3_HUMAN MMP3 Stromelysin-1 8.929e-06 0.40
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 9.182e-06 0.32
HNF4A_RAT Hnf4a Hepatocyte nuclear factor 4-alpha 9.297e-06 0.32
DHI1_HUMAN HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 9.536e-06 0.39

Epinephrine

ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 5.379e-55 1.00
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 4.008e-34 1.00
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 1.223e-12 1.00
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 7.992e-84 0.69
ADA2A_MOUSE Adra2a Alpha-2A adrenergic receptor 1.588e-72 0.58
ADA2C_MOUSE Adra2c Alpha-2C adrenergic receptor 1.588e-72 0.58
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 2.558e-57 0.69
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 1.633e-54 0.69
Q06347_9HIV2 reverse transcriptase Reverse transcriptase 1.932e-45 0.36
ADRB3_MOUSE Adrb3 Beta-3 adrenergic receptor 1.071e-38 0.31
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 2.032e-36 0.69
G3HDX1_CRIGR Alpha-1B adrenergic receptor 4.758e-31 0.61
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 1.907e-30 0.69
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.706e-27 0.69
H9TVJ1_CHISP TyR1 1.635e-25 0.31
ARP19_RAT Arpp19 cAMP-regulated phosphoprotein 19 7.913e-25 0.31
Q39829_SOYBN Lipoxygenase 3.395e-23 0.37
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 4.047e-23 0.69
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 3.93e-22 0.69
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 2.265e-19 0.63
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 9.773e-19 0.69
GRPE_ECOLI grpE Protein GrpE 8.104e-18 0.28
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 1.11e-16 0.34
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 2.22e-16 0.69
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 2.599e-13 0.30
RNH1_HUMAN RNASEH1 Ribonuclease H1 3.075e-12 0.36
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 2.193e-11 0.37
Q2PCB5_DICLA ca Carbonic anhydrase 1.105e-10 0.29
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 2.972e-10 0.69
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 6.156e-10 0.47
COMT_PIG COMT Catechol O-methyltransferase 1.37e-09 0.30
TYRO_HUMAN TYR Tyrosinase 2.592e-09 0.31
Q49PX0_9POXV N1L N1L 4.042e-09 0.32
AOC3_HUMAN AOC3 Membrane primary amine oxidase 4.221e-08 0.36
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 5.101e-08 0.37
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 3.105e-07 0.32
AA2BR_RAT Adora2b Adenosine receptor A2b 7.214e-07 0.31
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 2.1e-06 0.37
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 5.23e-06 0.61

Risperidone

5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.274e-54 1.00
H10_HUMAN H1-0 Histone H1.0 1.089e-50 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 7.582e-45 1.00
DRD2_RAT Drd2 D(2) dopamine receptor 3.888e-44 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.76e-27 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 4.491e-20 1.00
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 2.37e-19 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 6.032e-19 1.00
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.758e-18 1.00
HRH1_CAVPO HRH1 Histamine H1 receptor 1.147e-17 1.00
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.11e-16 1.00
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.22e-15 1.00
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 4.105e-12 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 5.777e-12 1.00
DRD3_RAT Drd3 D(3) dopamine receptor 2.985e-11 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 4.18e-11 1.00
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 6.82e-11 1.00
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.384e-10 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 8.776e-10 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.937e-09 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 2.707e-09 1.00
HRH1_RAT Hrh1 Histamine H1 receptor 1.499e-08 1.00
DRD1_RAT Drd1 D(1A) dopamine receptor 8.893e-08 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 2.219e-07 1.00
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 3.655e-07 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 3.942e-07 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 2.289e-06 1.00
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 3.331e-06 1.00
DRD2_MOUSE Drd2 D(2) dopamine receptor 3.625e-06 1.00
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 4.355e-06 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 2.047e-05 1.00
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 0.0001749 1.00
DRD5_HUMAN DRD5 D(1B) dopamine receptor 0.0004562 1.00
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 0.001005 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 0.002212 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 0.002937 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.0139 1.00
DRD4_HUMAN DRD4 D(4) dopamine receptor 0.01947 1.00
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 0.04329 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.07074 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.08205 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.1394 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.6272 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.7197 1.00
ALBU_BOVIN ALB Serum albumin 8.747e-107 0.40
ACOD_HUMAN SCD Acyl-CoA desaturase 2.025e-17 0.43
SCRB1_HUMAN SCARB1 Scavenger receptor class B member 1 1.11e-16 0.30
CCR3_RAT Ccr3 C-C chemokine receptor type 3 2.442e-15 0.30
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.938e-13 0.49
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 3.4e-12 0.30
ACOD1_RAT Scd1 Acyl-CoA desaturase 1 1.738e-11 0.38
CCR3_MOUSE Ccr3 Probable C-C chemokine receptor type 3 2.448e-10 0.30
DRD1_MOUSE Drd1 D(1A) dopamine receptor 1.921e-08 0.46
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 5.293e-08 0.30
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.128e-06 0.47
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 5.186e-06 0.36

Astemizole

SSR5_HUMAN SSTR5 Somatostatin receptor type 5 1.066e-53 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 2.751e-53 1.00
DRD4_HUMAN DRD4 D(4) dopamine receptor 3.879e-33 1.00
HRH1_CAVPO HRH1 Histamine H1 receptor 1.727e-32 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.964e-29 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.639e-25 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 3.666e-25 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 5.574e-18 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 2.726e-17 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 1.11e-16 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 4.219e-15 1.00
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 7.716e-14 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 8.937e-14 1.00
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 4.088e-13 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 7.043e-13 1.00
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 2.476e-12 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 3.237e-12 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.43e-11 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 6.584e-11 1.00
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 9.605e-11 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.099e-10 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 2.628e-10 1.00
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 3.838e-10 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 8.531e-09 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.33e-08 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.042e-07 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.128e-07 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.409e-07 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 2.525e-07 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 2.363e-06 1.00
OPRD_HUMAN OPRD1 Delta-type opioid receptor 5.729e-06 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.429e-05 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.909e-05 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 4.77e-05 1.00
HRH4_HUMAN HRH4 Histamine H4 receptor 5.192e-05 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.0003318 1.00
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 0.0007402 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.0007445 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.001291 1.00
NK2R_HUMAN TACR2 Substance-K receptor 0.001431 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.001476 1.00
NK1R_HUMAN TACR1 Substance-P receptor 0.001656 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.00381 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 0.01089 1.00
MC5R_HUMAN MC5R Melanocortin receptor 5 0.1414 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 0.4742 1.00
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 3.189e-74 0.34
DRD2_MOUSE Drd2 D(2) dopamine receptor 2.619e-69 0.43
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 6.376e-67 0.43
PDE6D_HUMAN PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 8.747e-65 0.39
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 6.18e-64 0.40
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 3.293e-61 0.42
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 2.408e-60 0.37
HMOX2_RAT Hmox2 Heme oxygenase 2 5.827e-55 0.45
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 2.254e-50 0.52
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 4.331e-50 0.37
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.438e-48 0.42
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.138e-44 0.48
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 6.539e-43 0.38
GLUT4_RAT Slc2a4 Solute carrier family 2, facilitated glucose transporter member 4 1.457e-36 0.29
GTR8_HUMAN SLC2A8 Solute carrier family 2, facilitated glucose transporter member 8 1.457e-36 0.29
NOS3_RAT Nos3 Nitric oxide synthase, endothelial 1.841e-36 0.32
PAQR1_HUMAN ADIPOR1 Adiponectin receptor protein 1 1.097e-35 0.28
PAQR2_HUMAN ADIPOR2 Adiponectin receptor protein 2 1.097e-35 0.28
NK1R_CAVPO TACR1 Substance-P receptor 8.053e-35 0.67
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 2.077e-33 0.32
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 5.773e-33 0.42
MTLR_HUMAN MLNR Motilin receptor 3.728e-32 0.36
B2L11_HUMAN BCL2L11 Bcl-2-like protein 11 1.042e-30 0.31
ASM_HUMAN SMPD1 Sphingomyelin phosphodiesterase 3.707e-30 0.41
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.331e-29 0.38
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 2.266e-29 0.42
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 1.392e-27 0.38
H4_HUMAN H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4-16 Histone H4 1.689e-27 0.53
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.731e-27 0.42
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 4.733e-27 0.42
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 5.913e-27 0.45
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 9.925e-27 0.35
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 1.308e-26 0.30
Q4DCQ3_TRYCC Superoxide dismutase 1.42e-25 0.32
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.507e-22 0.43
HNMT_RAT Hnmt Histamine N-methyltransferase 1.763e-22 0.30
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 3.003e-22 0.39
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 3.271e-22 0.41
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 1.539e-21 0.39
DRD2_RAT Drd2 D(2) dopamine receptor 3.307e-21 0.43
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.228e-20 0.42
CCR3_RAT Ccr3 C-C chemokine receptor type 3 6.278e-20 0.33
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 1.008e-19 0.34
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 4.371e-19 0.35
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 5.795e-19 0.35
CHLE_HORSE BCHE Cholinesterase 6.021e-19 0.44
EBPL_HUMAN EBPL Emopamil-binding protein-like 9.803e-19 0.30
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 2.045e-18 0.40
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 3.028e-18 0.29
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 3.274e-18 0.40
TGM2_MOUSE Tgm2 Protein-glutamine gamma-glutamyltransferase 2 3.886e-18 0.29
CCR3_MOUSE Ccr3 Probable C-C chemokine receptor type 3 6.86e-18 0.34
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 1.101e-17 0.43
DCPS_MOUSE Dcps m7GpppX diphosphatase 1.675e-17 0.29
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 2.103e-17 0.41
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 2.71e-17 0.41
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 5.295e-17 0.32
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 1.11e-16 0.31
DRD1_BOVIN DRD1 D(1A) dopamine receptor 2.22e-16 0.31
OPRX_HUMAN OPRL1 Nociceptin receptor 3.331e-16 0.34
PKR1_HUMAN PROKR1 Prokineticin receptor 1 4.441e-16 0.41
ACES_MOUSE Ache Acetylcholinesterase 7.772e-16 0.33
HRH3_HUMAN HRH3 Histamine H3 receptor 1.887e-15 0.41
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 3.22e-15 0.38
UR2R_HUMAN UTS2R Urotensin-2 receptor 3.775e-15 0.35
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 5.44e-15 0.33
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 3.12e-14 0.42
Q581W1_TRYB2 Pteridine reductase, putative 3.963e-14 0.31
LX15B_HUMAN ALOX15B Arachidonate 15-lipoxygenase B 2.043e-13 0.33
S6A12_HUMAN SLC6A12 Sodium- and chloride-dependent betaine transporter 3.235e-13 0.32
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 3.568e-13 0.36
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 3.614e-13 0.36
DRD5_HUMAN DRD5 D(1B) dopamine receptor 4.843e-13 0.37
DRD4_RAT Drd4 D(4) dopamine receptor 5.093e-13 0.32
SUV91_HUMAN SUV39H1 Histone-lysine N-methyltransferase SUV39H1 5.228e-13 0.35
ACES_ELEEL ache Acetylcholinesterase 1.178e-12 0.35
NORA_STAAU norA Quinolone resistance protein NorA 4.091e-12 0.31
TYTR_LEIDO TPR Trypanothione reductase 5.511e-12 0.29
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 6.269e-12 0.35
PLD2_HUMAN PLD2 Phospholipase D2 6.3e-12 0.35
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 6.835e-12 0.33
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 6.966e-12 0.29
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 8.289e-12 0.29
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 8.651e-12 0.37
GYRB_MYCTU gyrB DNA gyrase subunit B 1.014e-11 0.30
DCPS_HUMAN DCPS m7GpppX diphosphatase 1.087e-11 0.31
GRM2_HUMAN GRM2 Metabotropic glutamate receptor 2 1.205e-11 0.37
GPR6_HUMAN GPR6 G-protein coupled receptor 6 2.464e-11 0.32
DRD3_RAT Drd3 D(3) dopamine receptor 2.683e-11 0.33
DRD2_BOVIN DRD2 D(2) dopamine receptor 2.706e-11 0.34
PLD1_RAT Pld1 Phospholipase D1 3.07e-11 0.30
ACES_HUMAN ACHE Acetylcholinesterase 4.985e-11 0.41
GYRA_MYCTU gyrA DNA gyrase subunit A 5.573e-11 0.30
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.01e-10 0.35
O97467_PLAFA ht1 Hexose transporter 1 1.498e-10 0.38
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 1.717e-10 0.39
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 1.756e-10 0.38
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 3.258e-10 0.32
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 3.564e-10 0.38
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 3.655e-10 0.33
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 3.754e-10 0.38
PDE5A_HUMAN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 3.983e-10 0.40
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 5.129e-10 0.34
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 5.884e-10 0.47
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 6.822e-10 0.38
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 1.209e-09 0.31
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.492e-09 0.41
BKRB1_RAT Bdkrb1 B1 bradykinin receptor 1.656e-09 0.31
KCNA1_HUMAN KCNA1 Potassium voltage-gated channel subfamily A member 1 2.791e-09 0.29
AAPK2_HUMAN PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 2.866e-09 0.34
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 3.189e-09 0.29
AGTR1_BOVIN AGTR1 Type-1 angiotensin II receptor 3.58e-09 0.34
CASR_RAT Casr Extracellular calcium-sensing receptor 3.792e-09 0.28
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 3.953e-09 0.30
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 4.183e-09 0.40
AL5AP_HUMAN ALOX5AP Arachidonate 5-lipoxygenase-activating protein 5.259e-09 0.40
O61059_LEIME LmGT2 Glucose transporter 5.283e-09 0.38
HRH3_CAVPO HRH3 Histamine H3 receptor 5.37e-09 0.36
ANM8_HUMAN PRMT8 Protein arginine N-methyltransferase 8 5.811e-09 0.32
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 6.537e-09 0.30
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 8.223e-09 0.33
IL8_HUMAN CXCL8 Interleukin-8 9.163e-09 0.30
PLD1_HUMAN PLD1 Phospholipase D1 1.058e-08 0.35
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.187e-08 0.32
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 1.449e-08 0.33
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 2.354e-08 0.34
CBP_HUMAN CREBBP CREB-binding protein 2.72e-08 0.33
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 3.008e-08 0.38
FACE2_HUMAN RCE1 CAAX prenyl protease 2 4.419e-08 0.35
ACHP_LYMST Acetylcholine-binding protein 4.688e-08 0.34
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 5.576e-08 0.31
Q9WTR4_RAT Slc6a2 Transporter 6.411e-08 0.35
RGS4_HUMAN RGS4 Regulator of G-protein signaling 4 7.574e-08 0.35
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 9.328e-08 0.29
CHLE_HUMAN BCHE Cholinesterase 1.197e-07 0.33
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 1.548e-07 0.30
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.619e-07 0.32
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 1.652e-07 0.41
MEN1_HUMAN MEN1 Menin 1.826e-07 0.29
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 3.635e-07 0.39
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 4.075e-07 0.33
GNRHR_HUMAN GNRHR Gonadotropin-releasing hormone receptor 5.594e-07 0.34
SOAT1_MOUSE Soat1 Sterol O-acyltransferase 1 6.237e-07 0.34
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 6.689e-07 0.33
Q9WKE8_9HIV1 reverse transcriptase Reverse transcriptase 7.913e-07 0.36
ACES_BOVIN ACHE Acetylcholinesterase 7.983e-07 0.33
CCR4_MOUSE Ccr4 C-C chemokine receptor type 4 1.023e-06 0.28
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 1.295e-06 0.32
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 1.459e-06 0.32
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 2.52e-06 0.38
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 3.434e-06 0.30
ESR1_HUMAN ESR1 Estrogen receptor 3.64e-06 0.38
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 4.214e-06 0.34
G3I1B6_CRIGR 5-hydroxytryptamine receptor 4.502e-06 0.30
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 4.773e-06 0.34
5HT1B_CRIGR HTR1B 5-hydroxytryptamine receptor 1B 5.27e-06 0.30
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 5.68e-06 0.29
KCNQ1_HUMAN KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 5.968e-06 0.40
FABI_STAAR fabI Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI 7.59e-06 0.34
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 7.652e-06 0.28
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 8.346e-06 0.33
MERTK_HUMAN MERTK Tyrosine-protein kinase Mer 8.704e-06 0.34

Methazolamide

CAH4_BOVIN CA4 Carbonic anhydrase 4 1.14e-51 1.00
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 1.029e-33 1.00
Q5TU56_ANOGA 1272966 Carbonic anhydrase 2.399e-31 1.00
CAN_YEAST NCE103 Carbonic anhydrase 5.476e-30 1.00
C0IX24_STYPI CA2 Carbonic anhydrase 9.021e-29 1.00
B2V8E3_SULSY Carbonate dehydratase 1.129e-27 1.00
B5SU02_STYPI CA Alpha carbonic anhydrase 1.129e-27 1.00
Q31FD6_HYDCU Carbonic anhydrase, alpha family 1.129e-27 1.00
CYNT_HELPY cynT Carbonic anhydrase 8.553e-27 1.00
A6YCJ1_9METZ Astrosclerin-3 3.262e-26 1.00
CAH_METTE Carbonic anhydrase 1.949e-25 1.00
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 7.871e-25 1.00
CAH1_HUMAN CA1 Carbonic anhydrase 1 9.009e-25 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.916e-24 1.00
CAH15_MOUSE Ca15 Carbonic anhydrase 15 8.546e-19 1.00
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 2.828e-18 1.00
Q6FTL6_CANGA NCE103 Carbonic anhydrase 6.661e-16 1.00
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.938e-13 1.00
CAH3_HUMAN CA3 Carbonic anhydrase 3 1.175e-11 1.00
CAN_CANAL NCE103 Carbonic anhydrase 1.88e-11 1.00
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 2.018e-11 1.00
CAH13_MOUSE Ca13 Carbonic anhydrase 13 7.823e-11 1.00
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 3.814e-10 1.00
CAH6_HUMAN CA6 Carbonic anhydrase 6 6.452e-10 1.00
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 4.7e-09 1.00
CAH13_HUMAN CA13 Carbonic anhydrase 13 3.693e-08 1.00
CAH4_HUMAN CA4 Carbonic anhydrase 4 1.32e-07 1.00
CAH7_HUMAN CA7 Carbonic anhydrase 7 1.206e-05 1.00
CAH14_HUMAN CA14 Carbonic anhydrase 14 2.263e-05 1.00
CAH9_HUMAN CA9 Carbonic anhydrase 9 9.85e-05 1.00
CAH12_HUMAN CA12 Carbonic anhydrase 12 0.05597 1.00
CAH7_MOUSE Ca7 Carbonic anhydrase 7 8.534e-47 0.37
CAHX_FLABI Carbonic anhydrase 8.534e-47 0.37
Q9HVB9_PSEAE Carbonic anhydrase 3.096e-23 0.37
Q2PCB5_DICLA ca Carbonic anhydrase 1.138e-13 0.37
CAH11_HUMAN CA11 Carbonic anhydrase-related protein 11 6.189e-09 0.37
PDE7A_HUMAN PDE7A High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A 2.881e-07 0.37
CAH2_BOVIN CA2 Carbonic anhydrase 2 3.429e-06 0.37
Q9V396_DROME CAH1 Carbonic anhydrase 1 6.795e-06 0.37
Q9VTU8_DROME CAH2 Carbonic anhydrase 2, isoform A 6.795e-06 0.37

Imiquimod

TLR7_HUMAN TLR7 Toll-like receptor 7 2.548e-47 1.00
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 1.399e-11 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 0.002212 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.3224 1.00
TLR8_HUMAN TLR8 Toll-like receptor 8 6.015e-31 0.42
TGT_HUMAN QTRT1 Queuine tRNA-ribosyltransferase catalytic subunit 1 9.719e-24 0.29
SUMO1_HUMAN SUMO1 Small ubiquitin-related modifier 1 1.926e-23 0.29
PRIO_HUMAN PRNP Major prion protein 4.341e-19 0.32
3MG1_ECOLI tag DNA-3-methyladenine glycosylase 1 5.19e-19 0.30
AA1R_BOVIN ADORA1 Adenosine receptor A1 4.121e-17 0.45
P96884_MYCTO birA BirA bifunctional protein 1.221e-15 0.30
CA2D1_HUMAN CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 2.334e-12 0.32
SAHH_RAT Ahcy Adenosylhomocysteinase 2.981e-12 0.30
AA1R_HUMAN ADORA1 Adenosine receptor A1 4.578e-10 0.45
MURI_ENTFA murI Glutamate racemase 6.369e-10 0.31
DYR_YEAST DFR1 Dihydrofolate reductase 1.986e-09 0.29
Q9BJF5_TOXGO CDPK1 Calmodulin-domain protein kinase 1 3.196e-09 0.38
ATP4A_PIG ATP4A Potassium-transporting ATPase alpha chain 1 4.108e-09 0.30
TLR7_MOUSE Tlr7 Toll-like receptor 7 8.827e-09 0.37
AA3R_HUMAN ADORA3 Adenosine receptor A3 9.041e-09 0.45
CNOT7_HUMAN CNOT7 CCR4-NOT transcription complex subunit 7 2.057e-08 0.30
MK14_MOUSE Mapk14 Mitogen-activated protein kinase 14 2.951e-08 0.37
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 2.062e-07 0.31
ADA_BOVIN ADA Adenosine deaminase 6.587e-07 0.30
PERM_HUMAN MPO Myeloperoxidase 1.209e-06 0.34
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 1.336e-06 0.31
DYR_PNECA Dihydrofolate reductase 5.242e-06 0.30
F16P1_RAT Fbp1 Fructose-1,6-bisphosphatase 1 6.336e-06 0.29
MURI_HELPY murI Glutamate racemase 7.112e-06 0.29
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 7.672e-06 0.38
AA1R_RAT Adora1 Adenosine receptor A1 8.775e-06 0.38

Clofibrate

FABPL_RAT Fabp1 Fatty acid-binding protein, liver 6.223e-46 1.00
PIN4_HUMAN PIN4 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 9.362e-36 0.28
FABPI_HUMAN FABP2 Fatty acid-binding protein, intestinal 1.116e-27 0.54
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 9.44e-25 0.49
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 5.534e-18 0.36
DHI2_MOUSE Hsd11b2 Corticosteroid 11-beta-dehydrogenase isozyme 2 6.784e-18 0.40
COX2_HUMAN MT-CO2 Cytochrome c oxidase subunit 2 1.887e-15 0.29
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 2.331e-15 0.31
CAC1D_HUMAN CACNA1D Voltage-dependent L-type calcium channel subunit alpha-1D 6.328e-15 0.33
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.887e-14 0.36
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 4.63e-14 0.47
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 6.95e-14 0.31
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 2.275e-13 0.29
AMYP_RAT Amy2 Pancreatic alpha-amylase 3.922e-13 0.29
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 4.844e-13 0.33
A0A0Y9T855_PLABE DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 5.125e-13 0.28
A5K1N1_PLAVS Dihydroorotate dehydrogenase, mitochondrial, putative 5.125e-13 0.28
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 1.395e-12 0.44
GABR2_RAT Gabbr2 Gamma-aminobutyric acid type B receptor subunit 2 1.565e-12 0.30
Q8WMX0_BOVIN Muscarinic receptor M1 2.92e-12 0.29
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 3.393e-11 0.29
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 4.086e-11 0.30
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 6.609e-11 0.32
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 8.581e-11 0.29
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 1.105e-10 0.29
EST1_RABIT Liver carboxylesterase 1 1.582e-10 0.35
A1XG20_PENDI cyp51 Cytochrome P450 14alpha-demethylase 1.962e-10 0.38
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 3.928e-10 0.40
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 4.754e-10 0.32
PSBA_SPIOL psbA Photosystem II protein D1 1.621e-09 0.30
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 1.713e-09 0.32
GBRA2_HUMAN GABRA2 Gamma-aminobutyric acid receptor subunit alpha-2 2.708e-09 0.36
PPARD_MOUSE Ppard Peroxisome proliferator-activated receptor delta 2.822e-09 0.29
IMPA1_BOVIN IMPA1 Inositol monophosphatase 1 2.944e-09 0.31
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 2.944e-09 0.31
PSBA_MARPO psbA Photosystem II protein D1 3.598e-09 0.29
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 1.668e-08 0.30
GP119_HUMAN GPR119 Glucose-dependent insulinotropic receptor 2.573e-08 0.36
E3UJZ5_SPOLI Ecdysone receptor 2.961e-08 0.33
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 3.386e-08 0.29
DPOL_HHV6U U38 DNA polymerase catalytic subunit 3.985e-08 0.29
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 6.816e-08 0.29
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 1.056e-07 0.31
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 1.408e-07 0.30
ACRO_HUMAN ACR Acrosin 2.688e-07 0.33
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 4.905e-07 0.29
GBRG2_HUMAN GABRG2 Gamma-aminobutyric acid receptor subunit gamma-2 5.694e-07 0.36
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 7.167e-07 0.32
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 9.385e-07 0.35
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 9.493e-07 0.29
PTN12_HUMAN PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1.791e-06 0.30
ECR_BOMMO EcR Ecdysone receptor 2.461e-06 0.33
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 3.025e-06 0.30
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 4.749e-06 0.30
CCNC_HUMAN CCNC Cyclin-C 5.157e-06 0.30
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 5.235e-06 0.29
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 6.48e-06 0.44
PRTN3_HUMAN PRTN3 Myeloblastin 6.492e-06 0.33
USP_DROME usp Protein ultraspiracle 7.884e-06 0.31

Galantamine

ACES_TETCF ache Acetylcholinesterase 2.206e-45 1.00
Q9JKC1_RAT Bche Carboxylic ester hydrolase 7.827e-33 1.00
ACES_RAT Ache Acetylcholinesterase 2.128e-30 1.00
ACES_MOUSE Ache Acetylcholinesterase 0.0005085 1.00
ACES_HUMAN ACHE Acetylcholinesterase 0.0008406 1.00
ACES_ELEEL ache Acetylcholinesterase 0.00482 1.00
ACES_BOVIN ACHE Acetylcholinesterase 0.005207 1.00
CHLE_HUMAN BCHE Cholinesterase 0.1436 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.4751 1.00
CHLE_HORSE BCHE Cholinesterase 0.6331 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.9676 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.9994 1.00
OPRX_CAVPO OPRL1 Nociceptin receptor 1.265e-25 0.36
OPRM_HUMAN OPRM1 Mu-type opioid receptor 6.857e-24 0.43
OPRD_HUMAN OPRD1 Delta-type opioid receptor 2.93e-18 0.43
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 3.331e-16 0.43
OPRM_BOVIN OPRM1 Mu-type opioid receptor 1.361e-13 0.31
OPRM_MOUSE Oprm1 Mu-type opioid receptor 4.939e-12 0.41
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 1.107e-10 0.35
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.406e-09 0.38
ACHB4_MOUSE Chrnb4 Neuronal acetylcholine receptor subunit beta-4 4.089e-09 0.30
ACHB2_MOUSE Chrnb2 Neuronal acetylcholine receptor subunit beta-2 1.521e-08 0.30
OPRD_RAT Oprd1 Delta-type opioid receptor 3.349e-08 0.38
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.075e-07 0.36
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 9.345e-06 0.36

Tamoxifen

PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 2.981e-45 1.00
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 4.73e-18 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.08573 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.7866 1.00
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 3.195e-170 0.72
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 3.944e-161 0.67
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 9.729e-78 0.67
ACK1_MOUSE Tnk2 Activated CDC42 kinase 1 5.587e-45 0.34
ESR1_HUMAN ESR1 Estrogen receptor 7.114e-44 0.90
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 2.906e-41 0.35
ACH10_HUMAN CHRNA10 Neuronal acetylcholine receptor subunit alpha-10 2.281e-40 0.32
ACHA9_HUMAN CHRNA9 Neuronal acetylcholine receptor subunit alpha-9 2.281e-40 0.32
SAT1_HUMAN SAT1 Diamine acetyltransferase 1 3.824e-40 0.32
UR2R_MACMU UTS2R Urotensin-2 receptor 1.215e-35 0.28
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 5.029e-35 0.37
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 1.843e-31 0.56
ACRO_PIG ACR Acrosin 5.697e-31 0.38
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.653e-29 0.56
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 7.642e-29 0.45
NORA_STAAU norA Quinolone resistance protein NorA 2.525e-28 0.48
ERG2_YEAST ERG2 C-8 sterol isomerase 5.342e-24 0.56
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 3.786e-19 0.61
THA_HUMAN THRA Thyroid hormone receptor alpha 1.11e-16 0.37
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 3.331e-16 0.31
ESR2_HUMAN ESR2 Estrogen receptor beta 7.772e-16 0.64
LSS_HUMAN LSS Lanosterol synthase 7.772e-16 0.48
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.221e-15 0.39
HRH3_RAT Hrh3 Histamine H3 receptor 9.659e-15 0.46
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 2.887e-14 0.32
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 5.063e-14 0.35
CP19A_HUMAN CYP19A1 Aromatase 7.927e-14 0.70
AMYP_RAT Amy2 Pancreatic alpha-amylase 4.967e-13 0.28
HRH3_HUMAN HRH3 Histamine H3 receptor 1.877e-12 0.46
THB_HUMAN THRB Thyroid hormone receptor beta 2.242e-12 0.37
UR2R_HUMAN UTS2R Urotensin-2 receptor 2.662e-12 0.36
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 3.428e-12 0.48
S100B_HUMAN S100B Protein S100-B 7.054e-11 0.32
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 1.956e-10 0.37
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 2.582e-10 0.33
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 2.709e-10 0.39
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 3.478e-10 0.35
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 4.011e-10 0.32
HSF1_HUMAN HSF1 Heat shock factor protein 1 4.895e-10 0.33
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 3.324e-09 0.35
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 3.524e-09 0.37
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 4.818e-09 0.34
HRH3_CAVPO HRH3 Histamine H3 receptor 6.251e-09 0.38
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.171e-08 0.30
HRH1_HUMAN HRH1 Histamine H1 receptor 1.538e-08 0.38
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 8.156e-08 0.31
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 1.986e-07 0.30
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 5.691e-07 0.31
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 6.699e-07 0.32
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 8.308e-07 0.38
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 8.529e-07 0.32
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 8.942e-07 0.31
ERR1_HUMAN ESRRA Steroid hormone receptor ERR1 9.097e-07 0.67
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.612e-06 0.33
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 2.653e-06 0.30
AGP1_YEAST AGP1 General amino acid permease AGP1 3.392e-06 0.30
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 4.902e-06 0.56
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 5.277e-06 0.31
RARB_HUMAN RARB Retinoic acid receptor beta 6.687e-06 0.35
HRH2_HUMAN HRH2 Histamine H2 receptor 8.304e-06 0.31

Delavirdine

Q72547_9HIV1 pol Reverse transcriptase/RNaseH 4.173e-41 1.00
Q9WKE8_9HIV1 reverse transcriptase Reverse transcriptase 0.2061 1.00
KPYR_HUMAN PKLR Pyruvate kinase PKLR 1.342e-139 0.38
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 1.642e-55 0.48
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 2.066e-42 0.30
HRH4_HUMAN HRH4 Histamine H4 receptor 3.545e-31 0.43
Q91ZY3_CAVPO HRH4 Histamine H4 receptor 1.27e-25 0.41
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 4.446e-23 0.37
O70424_RAT Neuropeptide Y-Y2 receptor 7.502e-18 0.28
Q7K6A1_PLAF7 Histone deacetylase 7.502e-18 0.28
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 4.21e-17 0.29
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 1.366e-14 0.53
HRH4_MOUSE Hrh4 Histamine H4 receptor 3.286e-14 0.41
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 3.604e-13 0.30
BCAT1_HUMAN BCAT1 Branched-chain-amino-acid aminotransferase, cytosolic 3.656e-13 0.28
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 1.933e-11 0.37
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 9.176e-11 0.31
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.107e-10 0.37
HRH4_RAT Hrh4 Histamine H4 receptor 9.17e-09 0.41
GYRB_MYCS2 gyrB DNA gyrase subunit B 9.928e-09 0.38
GPR6_HUMAN GPR6 G-protein coupled receptor 6 1.279e-08 0.32
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 4.401e-08 0.31
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 1.646e-07 0.36
HRH1_CAVPO HRH1 Histamine H1 receptor 5.897e-07 0.41
MP2K6_HUMAN MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 2.779e-06 0.32
FAK2_MOUSE Ptk2b Protein-tyrosine kinase 2-beta 3.292e-06 0.29
P3C2B_HUMAN PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 4.393e-06 0.29

Nilutamide

ANDR_HUMAN AR Androgen receptor 2.668e-39 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.7315 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.8057 1.00
ANDR_RAT Ar Androgen receptor 6.402e-42 0.46
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 2.103e-26 0.33
PHOP1_HUMAN PHOSPHO1 Phosphoethanolamine/phosphocholine phosphatase 1.11e-16 0.33
PMM2_HUMAN PMM2 Phosphomannomutase 2 8.216e-15 0.33
TRXR2_PLAF7 trxr2 Thioredoxin reductase 2 2.175e-11 0.31

Prednisone

GCR_HUMAN NR3C1 Glucocorticoid receptor 2.78e-38 1.00
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 2.684e-94 0.69
ATTY_RAT Tat Tyrosine aminotransferase 1.065e-87 0.33
Q690N0_BOVIN PGR Progesterone receptor 3.225e-67 0.41
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.69e-49 0.66
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 3.535e-40 0.34
CP19A_HUMAN CYP19A1 Aromatase 5.722e-33 0.47
GCR_MOUSE Nr3c1 Glucocorticoid receptor 4.236e-32 0.69
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.218e-30 0.69
GCR_RAT Nr3c1 Glucocorticoid receptor 5.298e-25 0.69
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 3.349e-23 0.34
GLNA_HUMAN GLUL Glutamine synthetase 5.039e-21 0.69
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 1.048e-19 0.31
IL6_HUMAN IL6 Interleukin-6 1.11e-16 0.69
NOS2_RAT Nos2 Nitric oxide synthase, inducible 2.132e-14 0.32
PRGR_RAT Pgr Progesterone receptor 2.298e-14 0.31
ANDR_RAT Ar Androgen receptor 2.343e-14 0.41
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 4.707e-14 0.31
PRGR_RABIT PGR Progesterone receptor 1.21e-13 0.35
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 6.231e-13 0.32
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 6.097e-11 0.38
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.242e-09 0.32
ERG2_YEAST ERG2 C-8 sterol isomerase 4.48e-08 0.32
ANDR_MOUSE Ar Androgen receptor 1.102e-07 0.32
PPO2_AGABI PPO2 Polyphenol oxidase 2 4.638e-07 0.52
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 6.781e-07 0.33

Furosemide

CAH2_HUMAN CA2 Carbonic anhydrase 2 7.633e-36 1.00
CAH1_HUMAN CA1 Carbonic anhydrase 1 2.13e-35 1.00
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 8.103e-33 1.00
CAH6_HUMAN CA6 Carbonic anhydrase 6 4.412e-31 1.00
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 7.045e-28 1.00
CAH7_HUMAN CA7 Carbonic anhydrase 7 2.136e-25 1.00
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.118e-22 1.00
CAH4_HUMAN CA4 Carbonic anhydrase 4 2.316e-20 1.00
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.622e-20 1.00
CAH9_HUMAN CA9 Carbonic anhydrase 9 8.483e-18 1.00
CAH14_HUMAN CA14 Carbonic anhydrase 14 5.633e-12 1.00
CAH13_MOUSE Ca13 Carbonic anhydrase 13 2.804e-10 1.00
CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 4.222e-09 1.00
GPR35_HUMAN GPR35 G-protein coupled receptor 35 0.0008578 1.00
DHI1_MOUSE Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 0.1046 1.00
DHI1_HUMAN HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 0.9071 1.00
CAH4_BOVIN CA4 Carbonic anhydrase 4 2.184e-50 0.42
CAH13_HUMAN CA13 Carbonic anhydrase 13 2.705e-40 0.51
PGES2_HUMAN PTGES2 Prostaglandin E synthase 2 3.866e-31 0.32
CAH3_HUMAN CA3 Carbonic anhydrase 3 9.498e-31 0.51
GPAT1_MOUSE Gpam Glycerol-3-phosphate acyltransferase 1, mitochondrial 7.536e-30 0.29
CAH1_HORSE CA1 Carbonic anhydrase 1 3.624e-27 0.32
CHIT_YEAST CTS1 Endochitinase 4.036e-26 0.32
SOS1_HUMAN SOS1 Son of sevenless homolog 1 1.326e-20 0.33
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 4.308e-14 0.52
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 1.126e-13 0.31
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 1.463e-13 0.33
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 1.583e-11 0.42
LYPA1_HUMAN LYPLA1 Acyl-protein thioesterase 1 9.455e-11 0.29
MTSI_SPISQ sssIM CPG DNA methylase 2.125e-10 0.33
Q38C41_TRYB2 Phosphotransferase 2.538e-10 0.33
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 8.811e-10 0.28
MCL1_MOUSE Mcl1 Induced myeloid leukemia cell differentiation protein Mcl-1 homolog 1.16e-09 0.36
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 2.796e-09 0.52
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 5.897e-09 0.30
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 7.778e-09 0.29
EED_HUMAN EED Polycomb protein EED 8.789e-09 0.29
PLEC_HUMAN PLEC Plectin 1.113e-08 0.31
O77773_PIG Voltage-dependent calcium channel alpha-2 delta subunit 2.735e-08 0.33
KCNH3_HUMAN KCNH3 Potassium voltage-gated channel subfamily H member 3 3.54e-08 0.35
NEUR3_HUMAN NEU3 Sialidase-3 1.985e-07 0.35
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 2.537e-07 0.32
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 2.74e-07 0.30
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 3.55e-07 0.29
DGAT1_RAT Dgat1 Diacylglycerol O-acyltransferase 1 1.683e-06 0.29
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 1.697e-06 0.30
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 3.227e-06 0.52
5NTD_HUMAN NT5E 5'-nucleotidase 4.225e-06 0.29
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 4.429e-06 0.52
BKRB2_RAT Bdkrb2 B2 bradykinin receptor 4.793e-06 0.31
STABP_HUMAN STAMBP STAM-binding protein 6.358e-06 0.30
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 8.817e-06 0.31

Tamsulosin

ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 4.678e-32 1.00
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 3.484e-29 1.00
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.142e-28 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 5.107e-13 1.00
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 2.634e-10 1.00
ADA2B_RAT Adra2b Alpha-2B adrenergic receptor 3.385e-09 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.822e-08 1.00
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 2.553e-08 1.00
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 3.618e-07 1.00
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 3.888e-05 1.00
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 0.0002684 1.00
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 0.0194 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.02152 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 0.04204 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.1002 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 0.1407 1.00
RENI_CALJA REN Renin 5.753e-109 0.34
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 7.99e-82 0.38
SCMU_MYCTU Secreted chorismate mutase 2.419e-39 0.31
Q7M3D2_RABIT Renin 2.43e-36 0.29
RENI_HUMAN REN Renin 4.174e-19 0.34
RENI_MACMU REN Renin 3.886e-18 0.29
PGES2_HUMAN PTGES2 Prostaglandin E synthase 2 5.754e-18 0.38
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 6.55e-15 0.31
PTPRA_HUMAN PTPRA Receptor-type tyrosine-protein phosphatase alpha 2.32e-14 0.29
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 3.83e-14 0.51
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 1.356e-13 0.38
ILVB_YEAST ILV2 Acetolactate synthase catalytic subunit, mitochondrial 7.571e-11 0.34
RENI1_MOUSE Ren1 Renin-1 9.695e-11 0.29
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.105e-10 0.29
DRTS_PLAFK Bifunctional dihydrofolate reductase-thymidylate synthase 2.324e-10 0.31
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 3.362e-10 0.36
PPBT_HUMAN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 4.215e-09 0.34
CAH1_HORSE CA1 Carbonic anhydrase 1 1.512e-08 0.28
CALM1_HUMAN CALM1 Calmodulin-1 3.548e-08 0.29
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 7.127e-08 0.29
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.704e-07 0.34
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 2.267e-07 0.31
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 3.513e-07 0.29
FDFT_RAT Fdft1 Squalene synthase 7.265e-07 0.33
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 7.75e-07 0.37
O61059_LEIME LmGT2 Glucose transporter 9.881e-07 0.37
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 1.189e-06 0.29
CAH2_HUMAN CA2 Carbonic anhydrase 2 2.358e-06 0.37
CAH14_HUMAN CA14 Carbonic anhydrase 14 3.242e-06 0.37
KIFC1_HUMAN KIFC1 Kinesin-like protein KIFC1 3.422e-06 0.31
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 3.597e-06 0.28
O97467_PLAFA ht1 Hexose transporter 1 4.891e-06 0.37
CAH9_HUMAN CA9 Carbonic anhydrase 9 4.94e-06 0.37

Cefixime

PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 7.773e-24 1.00
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 1.341e-08 1.00
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 2.25e-08 1.00
STRP_STRP1 ska Streptokinase A 3.233e-06 1.00
MMP2_HUMAN MMP2 72 kDa type IV collagenase 0.7963 1.00
PBPA_PSEAE mrcA Penicillin-binding protein 1A 5.176e-90 0.42
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 8.356e-75 0.62
B2ZTR6_ACIBA Beta-lactamase 3.075e-63 0.62
D6NSM8_ACIBA ampC Beta-lactamase 3.075e-63 0.62
Q83TT7_ECOLX ampC AmpC 5.93e-63 0.42
Q7DHH4_STAAU mecA MecA 7.269e-55 0.44
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 3.782e-46 0.62
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 8.505e-42 0.62
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 1.527e-33 0.42
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 2.883e-28 0.35
Q3S5C3_SALNE sugE Efflux transporter 6.439e-26 0.42
Q48435_KLEPN bla LAT-2 Beta-lactamase 6.439e-26 0.42
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 2.237e-19 0.35
A2RP81_CITFR blaPER-2 Beta-lactamase 8.928e-19 0.42
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.206e-17 0.34
AMPC_CITFR ampC Beta-lactamase 3.775e-15 0.38
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.486e-12 0.59
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 6.943e-09 0.30
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 1.663e-06 0.79

Dyclonine

ACES_HUMAN ACHE Acetylcholinesterase 6.71e-20 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.477e-14 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.001616 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.001744 1.00
HRH3_HUMAN HRH3 Histamine H3 receptor 2.197e-191 0.69
HRH3_RAT Hrh3 Histamine H3 receptor 1.143e-170 0.83
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 4.028e-125 0.49
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.117e-110 0.63
HRH1_HUMAN HRH1 Histamine H1 receptor 1.331e-107 0.70
ESR1_HUMAN ESR1 Estrogen receptor 1.811e-103 0.57
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 6.526e-91 0.51
HNMT_RAT Hnmt Histamine N-methyltransferase 5.408e-89 0.37
ESR2_HUMAN ESR2 Estrogen receptor beta 7.464e-85 0.50
THB_HUMAN THRB Thyroid hormone receptor beta 1.031e-81 0.93
HRH2_HUMAN HRH2 Histamine H2 receptor 5.854e-80 0.70
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 7.3e-80 0.40
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.217e-79 0.34
NORA_STAAU norA Quinolone resistance protein NorA 1.225e-79 0.41
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 4.216e-74 0.66
Q4DCQ3_TRYCC Superoxide dismutase 2.946e-72 0.47
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 1.751e-65 0.33
HRH3_CAVPO HRH3 Histamine H3 receptor 1.094e-63 0.49
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 2.48e-63 0.93
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 4.746e-59 0.36
HRH3_MOUSE Hrh3 Histamine H3 receptor 1.091e-57 0.53
PA24A_HUMAN PLA2G4A Cytosolic phospholipase A2 5.141e-56 0.40
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 5.754e-56 0.33
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 7.308e-56 0.42
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 3.914e-55 0.41
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 2.146e-48 0.71
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 6.417e-48 0.38
ACES_ELEEL ache Acetylcholinesterase 2.967e-47 0.51
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 5.884e-46 0.66
HRH2_CAVPO HRH2 Histamine H2 receptor 1.91e-45 0.43
GGYF2_HUMAN GIGYF2 GRB10-interacting GYF protein 2 7.532e-45 0.36
THA_HUMAN THRA Thyroid hormone receptor alpha 2.817e-44 0.93
CHLE_HORSE BCHE Cholinesterase 5.37e-44 0.51
ACES_MOUSE Ache Acetylcholinesterase 3.397e-43 0.36
DRD4_RAT Drd4 D(4) dopamine receptor 5.335e-43 0.42
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 3.034e-42 0.41
SAT1_HUMAN SAT1 Diamine acetyltransferase 1 5.166e-42 0.33
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 7.746e-41 0.71
UR2R_MACMU UTS2R Urotensin-2 receptor 4.067e-39 0.31
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 8.272e-39 0.45
D4ADR1_RAT Lpar5 Lysophosphatidic acid receptor 5 1.023e-37 0.30
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.044e-37 0.49
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.81e-37 0.46
DRD1_PIG DRD1 D(1A) dopamine receptor 3.521e-37 0.37
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 3.473e-36 0.46
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 6.029e-36 0.43
PAQR1_HUMAN ADIPOR1 Adiponectin receptor protein 1 1.377e-35 0.28
PAQR2_HUMAN ADIPOR2 Adiponectin receptor protein 2 1.377e-35 0.28
ESR1_RAT Esr1 Estrogen receptor 3.234e-34 0.44
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 5.536e-34 0.41
TERT_HUMAN TERT Telomerase reverse transcriptase 4.281e-33 0.35
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 2.031e-32 0.33
MEN1_HUMAN MEN1 Menin 6.473e-32 0.33
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 6.633e-32 0.30
H10_HUMAN H1-0 Histone H1.0 1.7e-31 0.33
ERG2_YEAST ERG2 C-8 sterol isomerase 2.003e-31 0.40
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 3.72e-31 0.66
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 3.889e-31 0.46
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 1.209e-30 0.39
Q6Q253_PIG 5-HT4R 5-hydroxytryptamine receptor 4 protein 1.379e-30 0.29
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 2.056e-30 0.42
CLTR2_HUMAN CYSLTR2 Cysteinyl leukotriene receptor 2 9.501e-30 0.31
IKKB_MOUSE Ikbkb Inhibitor of nuclear factor kappa-B kinase subunit beta 4.37e-29 0.37
Q53I59_TRYCR PDEC Phosphodiesterase 4.895e-29 0.33
DRD2_HUMAN DRD2 D(2) dopamine receptor 5.396e-29 0.42
Q9JKC1_RAT Bche Carboxylic ester hydrolase 6.978e-29 0.48
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 4.061e-28 0.31
DRD4_HUMAN DRD4 D(4) dopamine receptor 4.072e-28 0.39
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 5.92e-28 0.38
HRH1_CAVPO HRH1 Histamine H1 receptor 7.313e-28 0.45
ACRO_PIG ACR Acrosin 7.695e-28 0.33
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 2e-27 0.43
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 2.322e-27 0.35
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 5.014e-27 0.42
ZN664_CAVPO ZNF664 Zinc finger protein 664 5.245e-27 0.33
DRD2_RAT Drd2 D(2) dopamine receptor 6.256e-27 0.39
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 9.243e-27 0.36
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 9.726e-27 0.40
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 3.591e-26 0.46
CHLE_MOUSE Bche Cholinesterase 7.754e-26 0.29
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.851e-25 0.43
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 2.296e-25 0.44
ESR2_RAT Esr2 Estrogen receptor beta 3.628e-25 0.44
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 5.282e-25 0.46
5HT7R_MOUSE Htr7 5-hydroxytryptamine receptor 7 5.379e-25 0.31
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 5.38e-25 0.42
ACES_RAT Ache Acetylcholinesterase 6.748e-25 0.48
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 1.692e-24 0.39
MMP7_HUMAN MMP7 Matrilysin 1.869e-24 0.36
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 1.505e-23 0.30
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.892e-23 0.45
POLG_HE71B Genome polyprotein 6.377e-23 0.28
RARB_HUMAN RARB Retinoic acid receptor beta 6.455e-23 0.48
MMP1_HUMAN MMP1 Interstitial collagenase 9.164e-23 0.56
BMP4_HUMAN BMP4 Bone morphogenetic protein 4 9.168e-23 0.35
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.034e-22 0.39
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.355e-22 0.46
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 4.535e-22 0.59
DRD5_HUMAN DRD5 D(1B) dopamine receptor 8.041e-22 0.39
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 1.217e-20 0.35
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 1.475e-20 0.42
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 2.618e-20 0.36
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 3.072e-20 0.39
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 4.558e-20 0.32
MMP13_HUMAN MMP13 Collagenase 3 5.118e-20 0.50
PIR_HUMAN PIR Pirin 9.095e-20 0.30
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 9.42e-20 0.34
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 1.018e-19 0.35
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 1.582e-19 0.33
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 2.785e-19 0.46
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 4.1e-19 0.37
USP9X_HUMAN USP9X Probable ubiquitin carboxyl-terminal hydrolase FAF-X 1.126e-18 0.30
UR2R_HUMAN UTS2R Urotensin-2 receptor 1.226e-18 0.32
DRD2_MOUSE Drd2 D(2) dopamine receptor 3.458e-18 0.37
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 3.901e-18 0.47
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 4.838e-18 0.44
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.535e-17 0.38
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 2.844e-17 0.47
NR1H4_MOUSE Nr1h4 Bile acid receptor 3.995e-17 0.30
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.11e-16 0.33
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.11e-16 0.38
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.11e-16 0.47
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.11e-16 0.37
V1AR_RAT Avpr1a Vasopressin V1a receptor 3.331e-16 0.38
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 1.11e-15 0.43
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.11e-15 0.37
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.554e-15 0.34
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.554e-15 0.36
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 1.998e-15 0.34
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 3.331e-15 0.29
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 3.886e-15 0.37
DRD1_HUMAN DRD1 D(1A) dopamine receptor 3.997e-15 0.40
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 4.219e-15 0.37
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 6.439e-15 0.48
MMP3_HUMAN MMP3 Stromelysin-1 8.216e-15 0.37
AGTR1_PIG AGTR1 Type-1 angiotensin II receptor 1.654e-14 0.32
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 1.998e-14 0.36
PA21B_PIG PLA2G1B Phospholipase A2, major isoenzyme 2.465e-14 0.34
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 2.72e-14 0.42
GYRB_MYCSM gyrB DNA gyrase subunit B 2.887e-14 0.35
CASB_RAT Csn2 Beta-casein 4.43e-14 0.31
CP26B_HUMAN CYP26B1 Cytochrome P450 26B1 4.752e-14 0.32
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 6.473e-14 0.44
ROCK2_RAT Rock2 Rho-associated protein kinase 2 7.272e-14 0.28
SNRK_HUMAN SNRK SNF-related serine/threonine-protein kinase 7.316e-14 0.30
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 8.371e-14 0.38
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 1.253e-13 0.44
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 1.436e-13 0.35
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.563e-13 0.34
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.733e-13 0.44
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 2.329e-13 0.37
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 3.295e-13 0.48
5HT3B_MOUSE Htr3b 5-hydroxytryptamine receptor 3B 3.612e-13 0.32
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 5.249e-13 0.50
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 5.99e-13 0.30
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 7.057e-13 0.47
YES_HUMAN YES1 Tyrosine-protein kinase Yes 7.51e-13 0.35
GP174_HUMAN GPR174 Probable G-protein coupled receptor 174 8.6e-13 0.28
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 9.177e-13 0.35
ADA_HUMAN ADA Adenosine deaminase 9.645e-13 0.31
GNAI1_HUMAN GNAI1 Guanine nucleotide-binding protein G(i) subunit alpha-1 1.036e-12 0.31
GNAI3_HUMAN GNAI3 Guanine nucleotide-binding protein G(i) subunit alpha 1.036e-12 0.31
P2Y10_HUMAN P2RY10 Putative P2Y purinoceptor 10 1.244e-12 0.29
LSS_HUMAN LSS Lanosterol synthase 1.645e-12 0.33
FFAR4_MOUSE Ffar4 Free fatty acid receptor 4 1.81e-12 0.31
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 4.571e-12 0.36
CLTR1_HUMAN CYSLTR1 Cysteinyl leukotriene receptor 1 4.785e-12 0.31
Q63380_RAT NET Transporter 5.247e-12 0.42
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 7.014e-12 0.31
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 9.64e-12 0.35
CNR2_HUMAN CNR2 Cannabinoid receptor 2 1.011e-11 0.42
RARA_HUMAN RARA Retinoic acid receptor alpha 1.041e-11 0.48
CNR1_RAT Cnr1 Cannabinoid receptor 1 1.235e-11 0.42
CEGT_HUMAN UGCG Ceramide glucosyltransferase 1.343e-11 0.33
GNAO_HUMAN GNAO1 Guanine nucleotide-binding protein G(o) subunit alpha 1.462e-11 0.31
S100B_HUMAN S100B Protein S100-B 2.335e-11 0.33
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 2.344e-11 0.59
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 2.873e-11 0.30
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 3.007e-11 0.35
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 4.102e-11 0.35
DRD1_RAT Drd1 D(1A) dopamine receptor 5.023e-11 0.37
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 7.218e-11 0.32
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 8.184e-11 0.44
ADA17_RAT Adam17 Disintegrin and metalloproteinase domain-containing protein 17 8.191e-11 0.29
CHLE_HUMAN BCHE Cholinesterase 8.333e-11 0.50
DRD1_MOUSE Drd1 D(1A) dopamine receptor 9.194e-11 0.30
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 9.452e-11 0.35
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 9.543e-11 0.38
HNF4A_RAT Hnf4a Hepatocyte nuclear factor 4-alpha 1.164e-10 0.31
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 1.441e-10 0.33
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 1.441e-10 0.33
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 1.495e-10 0.32
BMPR2_HUMAN BMPR2 Bone morphogenetic protein receptor type-2 1.627e-10 0.35
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 1.853e-10 0.37
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 2.102e-10 0.37
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 2.194e-10 0.30
NEK11_HUMAN NEK11 Serine/threonine-protein kinase Nek11 2.194e-10 0.30
SC5A7_HUMAN SLC5A7 High affinity choline transporter 1 2.922e-10 0.34
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 3.315e-10 0.39
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 3.358e-10 0.38
AHR_RABIT AHR Aryl hydrocarbon receptor 3.788e-10 0.31
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 4.055e-10 0.37
ACES_ANOGA Ace Acetylcholinesterase 6.239e-10 0.41
DRD5_RAT Drd5 D(1B) dopamine receptor 6.439e-10 0.29
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 7.449e-10 0.41
O61059_LEIME LmGT2 Glucose transporter 7.478e-10 0.41
TLR9_HUMAN TLR9 Toll-like receptor 9 7.658e-10 0.38
V1BR_RAT Avpr1b Vasopressin V1b receptor 9.066e-10 0.32
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 1.058e-09 0.38
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.109e-09 0.37
STK38_HUMAN STK38 Serine/threonine-protein kinase 38 1.147e-09 0.30
HSF1_HUMAN HSF1 Heat shock factor protein 1 1.205e-09 0.30
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.323e-09 0.36
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 1.475e-09 0.32
MET_HUMAN MET Hepatocyte growth factor receptor 1.7e-09 0.41
ENPP2_RAT Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.823e-09 0.30
DRD3_CHLAE DRD3 D(3) dopamine receptor 2.37e-09 0.33
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 2.436e-09 0.35
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 2.958e-09 0.47
LSS_RAT Lss Lanosterol synthase 3.644e-09 0.30
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 4.546e-09 0.30
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 5.092e-09 0.36
Q6L5J4_HUMAN FPRL2 FML2_HUMAN 5.31e-09 0.36
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 5.427e-09 0.35
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 5.844e-09 0.41
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 5.854e-09 0.39
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 6.029e-09 0.40
Q865E1_MACMU HRH3 Histamine receptor H3 6.095e-09 0.46
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 6.182e-09 0.37
SCAF_HCMVA UL80 Capsid scaffolding protein 6.248e-09 0.34
O97467_PLAFA ht1 Hexose transporter 1 6.841e-09 0.41
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 7.167e-09 0.33
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 9.025e-09 0.41
MIF_MOUSE Mif Macrophage migration inhibitory factor 9.882e-09 0.29
HNF4A_HUMAN HNF4A Hepatocyte nuclear factor 4-alpha 1.069e-08 0.31
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 1.462e-08 0.30
TLK2_HUMAN TLK2 Serine/threonine-protein kinase tousled-like 2 1.462e-08 0.30
SYLC_HUMAN LARS1 Leucine--tRNA ligase, cytoplasmic 1.751e-08 0.28
LYAG_MOUSE Gaa Lysosomal alpha-glucosidase 2.553e-08 0.33
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 2.77e-08 0.31
STS_HUMAN STS Steryl-sulfatase 2.946e-08 0.42
SQHC_ALIAD shc Squalene--hopene cyclase 2.992e-08 0.30
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 3.041e-08 0.41
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 3.257e-08 0.34
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 3.262e-08 0.43
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 3.767e-08 0.35
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 3.998e-08 0.30
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 3.998e-08 0.30
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 3.998e-08 0.30
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 3.998e-08 0.30
BMR1B_HUMAN BMPR1B Bone morphogenetic protein receptor type-1B 4.004e-08 0.35
CATK_RABIT CTSK Cathepsin K 4.743e-08 0.32
NR1H4_HUMAN NR1H4 Bile acid receptor 4.966e-08 0.38
CDK16_HUMAN CDK16 Cyclin-dependent kinase 16 5.208e-08 0.32
PGDH_HUMAN HPGD 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 5.337e-08 0.43
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 5.529e-08 0.34
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 6.924e-08 0.30
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 7.695e-08 0.41
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 8.315e-08 0.35
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 9.308e-08 0.43
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 9.575e-08 0.35
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 9.613e-08 0.30
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 1.32e-07 0.36
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 1.386e-07 0.30
GRIK2_RAT Grik2 Glutamate receptor ionotropic, kainate 2 1.46e-07 0.36
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 1.578e-07 0.43
CHKA_HUMAN CHKA Choline kinase alpha 1.588e-07 0.31
A5A4K8_RABIT MLNR Motilin receptor 1.652e-07 0.30
CXCR1_HUMAN CXCR1 C-X-C chemokine receptor type 1 1.999e-07 0.32
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 2.083e-07 0.30
NEK5_HUMAN NEK5 Serine/threonine-protein kinase Nek5 2.083e-07 0.30
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 2.083e-07 0.30
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 2.083e-07 0.30
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 2.083e-07 0.30
SRPK2_HUMAN SRPK2 SRSF protein kinase 2 2.083e-07 0.30
STK11_HUMAN STK11 Serine/threonine-protein kinase STK11 2.083e-07 0.30
TLK1_HUMAN TLK1 Serine/threonine-protein kinase tousled-like 1 2.083e-07 0.30
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 2.112e-07 0.35
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 2.142e-07 0.32
PA_I34A1 PA Polymerase acidic protein 2.184e-07 0.31
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 2.192e-07 0.32
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 2.251e-07 0.31
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 2.394e-07 0.35
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 2.449e-07 0.35
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 2.457e-07 0.31
GP119_HUMAN GPR119 Glucose-dependent insulinotropic receptor 2.523e-07 0.36
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.409e-07 0.33
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 3.477e-07 0.32
NIM1_HUMAN NIM1K Serine/threonine-protein kinase NIM1 4.144e-07 0.30
PRP4B_HUMAN PRPF4B Serine/threonine-protein kinase PRP4 homolog 4.144e-07 0.30
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 4.144e-07 0.30
MMP2_HUMAN MMP2 72 kDa type IV collagenase 4.243e-07 0.37
GRM3_RAT Grm3 Metabotropic glutamate receptor 3 4.503e-07 0.33
PPO2_AGABI PPO2 Polyphenol oxidase 2 4.524e-07 0.31
Q43570_TOBAC NtBBF1.1 Zn finger protein 6.322e-07 0.28
ACK1_MOUSE Tnk2 Activated CDC42 kinase 1 6.373e-07 0.28
SPHK2_HUMAN SPHK2 Sphingosine kinase 2 6.445e-07 0.32
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 7.441e-07 0.34
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 7.679e-07 0.30
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 7.679e-07 0.30
AGP1_YEAST AGP1 General amino acid permease AGP1 7.715e-07 0.34
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 8.598e-07 0.35
TYTR_TRYBB TPR Trypanothione reductase 8.664e-07 0.58
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 1.017e-06 0.32
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 1.078e-06 0.32
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 1.224e-06 0.42
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.248e-06 0.33
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 1.305e-06 0.35
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 1.34e-06 0.30
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 1.34e-06 0.30
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 1.34e-06 0.30
PLM2_PLAFA Plasmepsin-2 1.377e-06 0.39
EST1_RABIT Liver carboxylesterase 1 1.463e-06 0.29
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 1.487e-06 0.32
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 1.571e-06 0.32
AURKA_HUMAN AURKA Aurora kinase A 1.841e-06 0.37
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 1.985e-06 0.29
SHH_MOUSE Shh Sonic hedgehog protein 2.054e-06 0.32
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 2.213e-06 0.39
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 2.222e-06 0.30
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 2.222e-06 0.30
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 2.222e-06 0.30
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 2.477e-06 0.30
CHIT1_HUMAN CHIT1 Chitotriosidase-1 2.488e-06 0.30
ACACB_HUMAN ACACB Acetyl-CoA carboxylase 2 2.664e-06 0.38
HRH1_RAT Hrh1 Histamine H1 receptor 2.678e-06 0.33
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 2.853e-06 0.32
PTGES_HUMAN PTGES Prostaglandin E synthase 3.065e-06 0.36
IKKB_HUMAN IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 3.111e-06 0.39
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 3.391e-06 0.41
DRD3_RAT Drd3 D(3) dopamine receptor 3.513e-06 0.35
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 3.527e-06 0.30
INSRR_HUMAN INSRR Insulin receptor-related protein 3.527e-06 0.30
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 3.527e-06 0.30
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 3.527e-06 0.30
MYLK4_HUMAN MYLK4 Myosin light chain kinase family member 4 3.527e-06 0.30
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 3.578e-06 0.31
HRP1_PLAFA Histidine-rich protein PFHRP-II 4.011e-06 0.29
NCOA1_HUMAN NCOA1 Nuclear receptor coactivator 1 4.166e-06 0.31
FA10_BOVIN F10 Coagulation factor X 4.259e-06 0.29
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 4.519e-06 0.33
ACVR1_HUMAN ACVR1 Activin receptor type-1 4.619e-06 0.35
ACACA_HUMAN ACACA Acetyl-CoA carboxylase 1 4.849e-06 0.31
DRD2_CHLAE DRD2 D(2) dopamine receptor 5.201e-06 0.33
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 5.389e-06 0.30
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 5.389e-06 0.30
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 5.389e-06 0.30
PI42B_HUMAN PIP4K2B Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 5.389e-06 0.30
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 5.389e-06 0.30
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 5.474e-06 0.32
LPXC_PSEAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 5.979e-06 0.41
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 6.179e-06 0.39
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 6.843e-06 0.38
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 7.334e-06 0.33
ITB3_HUMAN ITGB3 Integrin beta-3 7.423e-06 0.35
AURKB_HUMAN AURKB Aurora kinase B 7.929e-06 0.37
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 7.965e-06 0.30
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 7.965e-06 0.30
GLI1_MOUSE Gli1 Zinc finger protein GLI1 8.281e-06 0.38
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 8.558e-06 0.28
CHIA_HUMAN CHIA Acidic mammalian chitinase 8.822e-06 0.30
CHIA_MOUSE Chia Acidic mammalian chitinase 8.822e-06 0.30
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 9.329e-06 0.31
LASR_PSEAE lasR Transcriptional activator protein LasR 9.374e-06 0.38
SKN1_CAEEL skn-1 Protein skinhead-1 9.617e-06 0.32

Mecamylamine

ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 1.359e-17 1.00
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 4.705e-17 1.00
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 1.11e-16 1.00
ACHA_HUMAN CHRNA1 Acetylcholine receptor subunit alpha 1.21e-14 1.00
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 1.77e-07 1.00
ACHA3_HUMAN CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 5.443e-07 1.00
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 1.983e-05 1.00
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 0.0001089 1.00
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 0.0001706 1.00

Meclizine

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.935e-17 1.00
HEPS_HUMAN HPN Serine protease hepsin 7.806e-07 1.00
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 1.262e-93 0.48
AMYP_PIG AMY2 Pancreatic alpha-amylase 2.176e-91 0.39
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 6.45e-81 0.48
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 9.345e-81 0.48
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 9.345e-81 0.48
DRD4_HUMAN DRD4 D(4) dopamine receptor 2.842e-74 0.48
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 4.384e-73 0.48
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.088e-54 0.46
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 7.598e-52 0.51
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 2.863e-49 0.48
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 2.434e-47 0.48
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 1.184e-46 0.39
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.527e-44 0.43
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.629e-44 0.54
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 1.997e-41 0.39
DRD2_MOUSE Drd2 D(2) dopamine receptor 2.108e-40 0.39
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 9.264e-40 0.32
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 7.271e-37 0.32
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.772e-35 0.51
OPRX_HUMAN OPRL1 Nociceptin receptor 2.375e-35 0.45
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.312e-34 0.43
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 2.554e-33 0.37
DRD1_BOVIN DRD1 D(1A) dopamine receptor 2.92e-33 0.40
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 1.219e-31 0.31
ACES_MOUSE Ache Acetylcholinesterase 2.654e-30 0.40
GP183_HUMAN GPR183 G-protein coupled receptor 183 3.79e-30 0.42
PA24A_HUMAN PLA2G4A Cytosolic phospholipase A2 4.371e-29 0.33
TYTR_TRYBB TPR Trypanothione reductase 2.66e-28 0.34
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.84e-26 0.49
OPRD_HUMAN OPRD1 Delta-type opioid receptor 7.179e-25 0.57
US28_HCMVA US28 G-protein coupled receptor homolog US28 4.112e-23 0.32
MGLL_MOUSE Mgll Monoglyceride lipase 4.846e-23 0.34
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 4.914e-23 0.40
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 2.619e-22 0.47
ACES_ELEEL ache Acetylcholinesterase 6.125e-21 0.42
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 2.129e-20 0.33
DRD2_RAT Drd2 D(2) dopamine receptor 6.07e-19 0.47
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.35e-18 0.45
PA_I000X PA Polymerase acidic protein 1.406e-18 0.36
AUKBA_XENLA aurkb-a Aurora kinase B-A 4.879e-18 0.29
EBPL_HUMAN EBPL Emopamil-binding protein-like 4.879e-18 0.29
SOS1_HUMAN SOS1 Son of sevenless homolog 1 4.879e-18 0.29
MGLL_HUMAN MGLL Monoglyceride lipase 7.831e-18 0.36
NOX5_HUMAN NOX5 NADPH oxidase 5 1.544e-17 0.29
Q9WTR4_RAT Slc6a2 Transporter 1.553e-17 0.39
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.715e-17 0.45
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 3.67e-17 0.39
CHKA_HUMAN CHKA Choline kinase alpha 3.901e-17 0.34
RGS8_HUMAN RGS8 Regulator of G-protein signaling 8 4.169e-17 0.31
DRD3_CHLAE DRD3 D(3) dopamine receptor 1.11e-16 0.32
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 4.441e-16 0.40
ACES_HUMAN ACHE Acetylcholinesterase 5.551e-16 0.42
PDIA1_HUMAN P4HB Protein disulfide-isomerase 7.772e-16 0.31
AL3A1_HUMAN ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 9.992e-16 0.37
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.11e-15 0.30
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 1.554e-15 0.44
Q9HUN3_PSEAE dnaB Replicative DNA helicase 1.998e-15 0.34
PA_I34A1 PA Polymerase acidic protein 2.554e-15 0.36
CHLE_HORSE BCHE Cholinesterase 3.22e-15 0.36
HRH3_HUMAN HRH3 Histamine H3 receptor 7.661e-15 0.40
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.621e-14 0.44
CY24B_HUMAN CYBB Cytochrome b-245 heavy chain 1.688e-14 0.29
RGS4_HUMAN RGS4 Regulator of G-protein signaling 4 1.932e-14 0.33
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 2.243e-14 0.44
S6A12_HUMAN SLC6A12 Sodium- and chloride-dependent betaine transporter 5.584e-14 0.34
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 9.77e-14 0.37
ACHP_LYMST Acetylcholine-binding protein 1.742e-13 0.33
HMOX2_RAT Hmox2 Heme oxygenase 2 1.892e-13 0.40
LSS_HUMAN LSS Lanosterol synthase 2.386e-13 0.37
AAKG1_HUMAN PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 2.992e-13 0.34
DRD1_PIG DRD1 D(1A) dopamine receptor 4.284e-13 0.39
PLPL6_MOUSE Pnpla6 Neuropathy target esterase 5.718e-13 0.30
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 1.299e-12 0.38
CASP5_HUMAN CASP5 Caspase-5 2.217e-12 0.35
HRH1_CAVPO HRH1 Histamine H1 receptor 2.446e-12 0.37
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 3.463e-12 0.44
AAPK2_HUMAN PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 5.932e-12 0.34
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 7.949e-12 0.34
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 8.324e-12 0.44
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 1.046e-11 0.44
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 2.83e-11 0.44
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 3.105e-11 0.33
RCE1_YEAST RCE1 CAAX prenyl protease 2 4.517e-11 0.40
MGLL_RAT Mgll Monoglyceride lipase 5.485e-11 0.32
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 5.583e-11 0.39
CNR1_HUMAN CNR1 Cannabinoid receptor 1 7.136e-11 0.40
CA2D1_HUMAN CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 9.832e-11 0.48
ABHD6_MOUSE Abhd6 Monoacylglycerol lipase ABHD6 1.23e-10 0.30
DRD2_CHLAE DRD2 D(2) dopamine receptor 1.835e-10 0.32
CNR1_RAT Cnr1 Cannabinoid receptor 1 2.4e-10 0.39
Q63380_RAT NET Transporter 4.043e-10 0.41
HRH1_HUMAN HRH1 Histamine H1 receptor 4.754e-10 0.51
OPRD_RAT Oprd1 Delta-type opioid receptor 4.922e-10 0.60
GP183_MOUSE Gpr183 G-protein coupled receptor 183 5.473e-10 0.28
CP19A_RAT Cyp19a1 Aromatase 5.511e-10 0.41
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 7.265e-10 0.30
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 8.511e-10 0.44
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 1.155e-09 0.33
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 1.407e-09 0.40
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 1.479e-09 0.30
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 2.743e-09 0.37
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 3.212e-09 0.34
AROK_HELPY aroK Shikimate kinase 4.864e-09 0.28
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 4.901e-09 0.36
NK1R_HUMAN TACR1 Substance-P receptor 5.204e-09 0.44
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 5.477e-09 0.33
CAC1I_HUMAN CACNA1I Voltage-dependent T-type calcium channel subunit alpha-1I 7.559e-09 0.40
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 1.093e-08 0.34
GPR6_HUMAN GPR6 G-protein coupled receptor 6 1.319e-08 0.37
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.685e-08 0.37
ACES_RAT Ache Acetylcholinesterase 5.087e-08 0.42
SKN1_CAEEL skn-1 Protein skinhead-1 5.218e-08 0.31
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 8.176e-08 0.29
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 1.075e-07 0.36
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.301e-07 0.34
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 1.336e-07 0.35
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 1.346e-07 0.30
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 1.462e-07 0.44
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 1.476e-07 0.33
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.619e-07 0.40
S12A5_RAT Slc12a5 Solute carrier family 12 member 5 2.67e-07 0.31
NOX4_HUMAN NOX4 NADPH oxidase 4 2.756e-07 0.31
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 3.05e-07 0.28
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 3.053e-07 0.30
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 3.071e-07 0.31
MC4R_HUMAN MC4R Melanocortin receptor 4 3.459e-07 0.43
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 4.443e-07 0.48
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 5.069e-07 0.30
VACHT_TETCF Vesicular acetylcholine transporter 6.414e-07 0.39
O97467_PLAFA ht1 Hexose transporter 1 6.86e-07 0.37
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 7.111e-07 0.46
O61059_LEIME LmGT2 Glucose transporter 7.666e-07 0.37
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 9.753e-07 0.37
PRIO_SHEEP PRNP Major prion protein 1.017e-06 0.31
CHLE_HUMAN BCHE Cholinesterase 1.159e-06 0.36
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 1.175e-06 0.32
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 1.31e-06 0.32
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 1.359e-06 0.29
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 1.507e-06 0.30
OPRM_RAT Oprm1 Mu-type opioid receptor 1.553e-06 0.60
NOX1_HUMAN NOX1 NADPH oxidase 1 2.454e-06 0.29
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 2.972e-06 0.34
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 3.133e-06 0.28
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 3.589e-06 0.54
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 3.847e-06 0.29
MIF_HUMAN MIF Macrophage migration inhibitory factor 4.103e-06 0.32
BRSK2_HUMAN BRSK2 Serine/threonine-protein kinase BRSK2 4.596e-06 0.29
CAC1H_HUMAN CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H 6.102e-06 0.40
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 6.64e-06 0.37
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 8.707e-06 0.37
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 8.956e-06 0.40
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 9.237e-06 0.33

Sufentanil

OPRM_RAT Oprm1 Mu-type opioid receptor 7.772e-16 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.1273 1.00
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 5.87e-31 0.36
B2ZTR6_ACIBA Beta-lactamase 2.984e-19 0.31
D6NSM8_ACIBA ampC Beta-lactamase 2.984e-19 0.31
A2RP81_CITFR blaPER-2 Beta-lactamase 5.307e-14 0.31
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 5.932e-11 0.29
CALM_BOVIN CALM Calmodulin 1.105e-10 0.29
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.724e-10 0.65
OPRM_HUMAN OPRM1 Mu-type opioid receptor 3.144e-10 0.75
NK2R_RAT Tacr2 Substance-K receptor 5.168e-10 0.32
BLA1_STEMA Metallo-beta-lactamase L1 type 3 1.582e-09 0.30
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 2.247e-09 0.29
HRH3_CAVPO HRH3 Histamine H3 receptor 2.858e-09 0.30
CNOT7_HUMAN CNOT7 CCR4-NOT transcription complex subunit 7 3.548e-08 0.29
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 2.732e-07 0.29
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 2.884e-07 0.33
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 3.472e-07 0.31
OPRM_MOUSE Oprm1 Mu-type opioid receptor 3.912e-07 0.75
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 4.265e-07 0.35
OPRD_HUMAN OPRD1 Delta-type opioid receptor 4.358e-07 0.75
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 5.048e-07 0.38
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 5.385e-07 0.31
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.747e-06 0.38
PDIA1_HUMAN P4HB Protein disulfide-isomerase 2.062e-06 0.28
OPRX_HUMAN OPRL1 Nociceptin receptor 3.814e-06 0.46
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 4.836e-06 0.29
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 5.327e-06 0.29
GCN5_YEAST GCN5 Histone acetyltransferase GCN5 5.99e-06 0.29
HRH2_HUMAN HRH2 Histamine H2 receptor 9.784e-06 0.31

Nitrofurantoin

CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 8.105e-15 1.00
STRP_STRP1 ska Streptokinase A 0.00157 1.00
MITF_HUMAN MITF Microphthalmia-associated transcription factor 3.553e-15 0.54
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 1.858e-11 0.39
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 1.683e-06 0.29

Verapamil

CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.366e-14 1.00
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.785e-14 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.31e-13 1.00
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 6.558e-13 1.00
CAC1S_RAT Cacna1s Voltage-dependent L-type calcium channel subunit alpha-1S 9.469e-13 1.00
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 2.504e-10 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 8.108e-09 1.00
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 9.101e-08 1.00
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 1.415e-07 1.00
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 3.888e-05 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 4.936e-05 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 0.0002773 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 0.0002947 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.0003858 1.00
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 0.003495 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.02959 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 0.03766 1.00
TSPO_RAT Tspo Translocator protein 0.1474 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.2156 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.3729 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 0.6182 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.8421 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.8702 1.00
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.624e-31 0.33
HCN1_MOUSE Hcn1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 2.461e-30 0.34
CAC1C_MOUSE Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 2.83e-30 0.38
HCN2_MOUSE Hcn2 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 5.42e-26 0.42
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2.325e-23 0.59
ERG2_YEAST ERG2 C-8 sterol isomerase 1.621e-19 0.59
AUR1_CANAL AUR1 Inositol phosphorylceramide synthase 2.036e-19 0.31
HCN4_HUMAN HCN4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 9.239e-19 0.42
ASM_HUMAN SMPD1 Sphingomyelin phosphodiesterase 1.11e-16 0.42
LYPA2_HUMAN LYPLA2 Acyl-protein thioesterase 2 6.736e-12 0.29
LYPA1_HUMAN LYPLA1 Acyl-protein thioesterase 1 7.946e-11 0.29
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.832e-10 0.87
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 5.575e-10 0.29
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 4.319e-07 0.36
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 5.904e-07 0.28
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 5.429e-06 0.31

Midazolam

S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.785e-14 1.00
TSPO_RAT Tspo Translocator protein 3.655e-10 1.00
AURKA_MOUSE Aurka Aurora kinase A 1.728e-87 0.55
AURKB_MOUSE Aurkb Aurora kinase B 7.877e-45 0.36
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 4.536e-29 0.54
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 6.132e-12 0.41
APEX1_HUMAN APEX1 DNA-(apurinic or apyrimidinic site) lyase 6.044e-07 0.32
TAT_HV112 tat Protein Tat 6.432e-07 0.31
CCKAR_RAT Cckar Cholecystokinin receptor type A 9.032e-07 0.35
GBRA1_HUMAN GABRA1 Gamma-aminobutyric acid receptor subunit alpha-1 1.033e-06 0.55
GBRA3_HUMAN GABRA3 Gamma-aminobutyric acid receptor subunit alpha-3 8.267e-06 0.50
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 8.541e-06 0.36

Stavudine

Q72547_9HIV1 pol Reverse transcriptase/RNaseH 4.123e-13 1.00
Q9WKE8_9HIV1 reverse transcriptase Reverse transcriptase 1.868e-10 1.00
KITH_HUMAN TK1 Thymidine kinase, cytosolic 1.217e-126 0.57
KITM_HUMAN TK2 Thymidine kinase 2, mitochondrial 9.735e-110 0.47
TYPH_RAT Tymp Thymidine phosphorylase 7.255e-107 0.44
KTHY_MYCTU tmk Thymidylate kinase 4.117e-94 0.49
DNK_DROME dnk Deoxynucleoside kinase 1.065e-81 0.43
A3RLP8_CHV1 UL23 Thymidine kinase 5.503e-76 0.57
TYSY_LACCA thyA Thymidylate synthase 1.038e-70 0.44
D3ZGQ2_RAT Tk2 Thymidine kinase 2 3.645e-57 0.46
KITH_RAT Tk1 Thymidine kinase, cytosolic 8.178e-56 0.49
KITH_HHV1S TK Thymidine kinase 2.375e-47 0.57
DPOD1_HUMAN POLD1 DNA polymerase delta catalytic subunit 1.968e-44 0.35
TYSY_MYCTU thyA Thymidylate synthase ThyA 5.881e-40 0.32
KITH_VZVD TK Thymidine kinase 1.405e-36 0.41
THYX_MYCTU thyX Flavin-dependent thymidylate synthase 5.22e-28 0.32
KITH_HHV1 TK Thymidine kinase 1.613e-27 0.53
KTHY_HUMAN DTYMK Thymidylate kinase 2.344e-26 0.30
TYSY_BOVIN TYMS Thymidylate synthase 9.841e-25 0.30
Q6L709_HHV2 TK Thymidine kinase 4.742e-24 0.33
DPOL_HHV1K DNA polymerase catalytic subunit 4.398e-22 0.35
TYPH_HUMAN TYMP Thymidine phosphorylase 1.446e-21 0.50
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 1.17e-17 0.42
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 3.331e-16 0.42
DPOL_HHV11 DNA polymerase catalytic subunit 4.441e-16 0.35
DPOL_VZVD DNA polymerase catalytic subunit 4.441e-16 0.35
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 9.548e-15 0.40
CHLE_HUMAN BCHE Cholinesterase 7.372e-14 0.52
P2RY6_RAT P2ry6 P2Y purinoceptor 6 8.116e-14 0.30
PYRF_METTH pyrF Orotidine 5'-phosphate decarboxylase 6.352e-13 0.32
DPOLB_HUMAN POLB DNA polymerase beta 1.076e-12 0.40
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 1.191e-12 0.31
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 1.76e-11 0.60
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 2.683e-10 0.42
TYSY_MOUSE Tyms Thymidylate synthase 2.877e-10 0.40
Q03732_HBV HBcAg Capsid protein 2.967e-10 0.57
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 2.932e-08 0.41
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 7.401e-08 0.42
Q9WJQ2_9HIV1 reverse transcriptase Reverse transcriptase protein 2.003e-07 0.60
Q8II92_PLAF7 Deoxyuridine 5'-triphosphate nucleotidohydrolase 1.218e-06 0.36
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 3.022e-06 0.32

Thioridazine

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 3.374e-12 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.005894 1.00
PIM1_HUMAN PIM1 Serine/threonine-protein kinase pim-1 0.1758 1.00
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 1.424e-112 0.47
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 4.449e-68 0.37
PRIO_MOUSE Prnp Major prion protein 3.502e-48 0.38
TYTR_TRYCR TPR Trypanothione reductase 4.261e-39 0.43
LYSC1_RAT Lyz1 Lysozyme C-1 4.986e-31 0.38
CALM_BOVIN CALM Calmodulin 2.322e-27 0.38
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 3.023e-25 0.31
BGLR_RAT Gusb Beta-glucuronidase 5.462e-24 0.38
EBPL_HUMAN EBPL Emopamil-binding protein-like 5.462e-24 0.38
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 1.512e-22 0.38
Q9IP65_HCMV US28 G protein-coupled receptor 1.945e-22 0.43
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 5.15e-21 0.31
CALM1_HUMAN CALM1 Calmodulin-1 1.544e-20 0.38
US28_HCMVA US28 G-protein coupled receptor homolog US28 8.882e-16 0.43
HRH1_HUMAN HRH1 Histamine H1 receptor 2.343e-14 0.42
ACHA9_RAT Chrna9 Neuronal acetylcholine receptor subunit alpha-9 1.257e-12 0.40
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 6.504e-12 0.42
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 1.303e-11 0.31
KCNJ3_RAT Kcnj3 G protein-activated inward rectifier potassium channel 1 1.684e-10 0.32
KCNJ5_RAT Kcnj5 G protein-activated inward rectifier potassium channel 4 1.684e-10 0.32
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 2.492e-10 0.38
CHLE_HORSE BCHE Cholinesterase 2.759e-10 0.67
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 4.867e-08 0.28
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 6.652e-08 0.37
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.114e-07 0.42
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.365e-07 0.28
HRH2_HUMAN HRH2 Histamine H2 receptor 1.392e-07 0.38
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 2.174e-07 0.32
ACHB2_RAT Chrnb2 Neuronal acetylcholine receptor subunit beta-2 3.272e-07 0.34
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 3.467e-07 0.38
ACHA4_RAT Chrna4 Neuronal acetylcholine receptor subunit alpha-4 5.035e-07 0.34
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 5.663e-07 0.31
NOX1_HUMAN NOX1 NADPH oxidase 1 5.77e-07 0.36
ACHA3_HUMAN CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 6.6e-07 0.32
DRD1_HUMAN DRD1 D(1A) dopamine receptor 8.274e-07 0.71
5HT6R_RAT Htr6 5-hydroxytryptamine receptor 6 1.31e-06 0.43
CNR1_RAT Cnr1 Cannabinoid receptor 1 1.389e-06 0.32
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 1.698e-06 0.28
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 1.894e-06 0.41
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 2.337e-06 0.30
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 3.36e-06 0.30
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 4.636e-06 0.42
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 9.867e-06 0.41

Isoflurophate

EST1_PIG Liver carboxylesterase 5.958e-10 1.00
PPGB_HUMAN CTSA Lysosomal protective protein 0.0948 1.00
ACES_ELEEL ache Acetylcholinesterase 0.2551 1.00
ACES_HUMAN ACHE Acetylcholinesterase 0.9519 1.00
BLAB_AERHY cphA Metallo-beta-lactamase type 2 3.603e-30 0.38
MGLL_MOUSE Mgll Monoglyceride lipase 2.522e-08 0.43

Benzyl_benzoate

LIPS_RAT Lipe Hormone-sensitive lipase 3.005e-07 1.00
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 2.694e-113 0.41
S12A5_RAT Slc12a5 Solute carrier family 12 member 5 4.173e-109 0.42
CATB_BOVIN CTSB Cathepsin B 8.754e-99 0.35
THER_BACTH npr Thermolysin 1.606e-90 0.36
CPNS1_PIG CAPNS1 Calpain small subunit 1 3.297e-85 0.33
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 1.416e-80 0.44
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 1.016e-72 0.40
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 2.85e-67 0.39
EST1_RABIT Liver carboxylesterase 1 3.437e-63 0.44
MCA2_TRYBB MCA2 Metacaspase 1.004e-62 0.38
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 1.344e-62 0.35
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 1.275e-61 0.34
PPCE_BOVIN PREP Prolyl endopeptidase 1.182e-60 0.38
KLK8_HUMAN KLK8 Kallikrein-8 5.985e-59 0.36
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 9.74e-59 0.33
PPCE_MOUSE Prep Prolyl endopeptidase 1.52e-58 0.35
GLT_PYRHO Glutamate transporter homolog 2.742e-57 0.46
CATB_RAT Ctsb Cathepsin B 3.364e-57 0.36
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 1.447e-55 0.50
Q8WSF8_APLCA Soluble acetylcholine receptor 1.842e-54 0.39
KLK4_HUMAN KLK4 Kallikrein-4 4.416e-54 0.36
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 2.031e-52 0.35
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 2.071e-52 0.50
SCAF_HHV11 UL26 Capsid scaffolding protein 3.329e-52 0.34
PHHY_PSEFL pobA p-hydroxybenzoate hydroxylase 1.372e-49 0.39
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 1.156e-45 0.43
Q8ILP4_PLAF7 Pantothenate kinase, putative 1.634e-45 0.36
CANX_CHICK Calpain-1 catalytic subunit 1.389e-44 0.35
PPCE_ELIME f1pep1 Prolyl endopeptidase 1.389e-44 0.35
UBE2B_HUMAN UBE2B Ubiquitin-conjugating enzyme E2 B 1.353e-43 0.35
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 6.689e-43 0.45
TGM1_HUMAN TGM1 Protein-glutamine gamma-glutamyltransferase K 1.133e-42 0.32
CATL1_RAT Ctsl Cathepsin L1 3.031e-42 0.29
CATH_RAT Ctsh Pro-cathepsin H 4.562e-42 0.36
UBP4_HUMAN USP4 Ubiquitin carboxyl-terminal hydrolase 4 5.166e-42 0.33
CATL1_HUMAN CTSL Cathepsin L1 6.03e-42 0.40
CBPA1_HUMAN CPA1 Carboxypeptidase A1 7.293e-42 0.35
CATB_HUMAN CTSB Cathepsin B 5.948e-41 0.41
BLA1_ECOLX bla Beta-lactamase SHV-1 1.67e-40 0.34
POLG_HRV14 Genome polyprotein 7.545e-40 0.32
Q9NAW4_PLAFA Cysteine protease falcipain-3 1.253e-39 0.31
SENP1_HUMAN SENP1 Sentrin-specific protease 1 6.159e-39 0.40
CYSP_TRYCR Cruzipain 7.516e-39 0.40
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 1.332e-38 0.44
KLK2_HUMAN KLK2 Kallikrein-2 4.115e-38 0.34
EST2_HUMAN CES2 Cocaine esterase 9.222e-38 0.44
NK1R_RAT Tacr1 Substance-P receptor 1.185e-37 0.45
Q99P97_RAT Histone deacetylase 6 1.225e-37 0.30
GLUP_BACSU gluP Rhomboid protease GluP 2.151e-37 0.31
MGLL_RAT Mgll Monoglyceride lipase 3.149e-37 0.47
EPOR_HUMAN EPOR Erythropoietin receptor 3.448e-37 0.31
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 7.502e-37 0.39
KLK3_HUMAN KLK3 Prostate-specific antigen 2.054e-36 0.42
Q72874_9HIV1 pol Pol polyprotein 2.857e-36 0.44
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 4.759e-36 0.46
SPLB_STAAU splB Serine protease SplB 7.62e-36 0.28
PAQR1_HUMAN ADIPOR1 Adiponectin receptor protein 1 8.333e-36 0.28
PAQR2_HUMAN ADIPOR2 Adiponectin receptor protein 2 8.333e-36 0.28
Q95PM0_TRYBR rhodesain Cysteine protease 2.486e-35 0.44
ACRO_PIG ACR Acrosin 3.158e-35 0.39
PAPA1_CARPA Papain 6.498e-35 0.38
HIS7_ECOLI hisB Histidine biosynthesis bifunctional protein HisB 1.688e-34 0.49
KLK_PIG Glandular kallikrein 6.108e-34 0.34
CATK_HUMAN CTSK Cathepsin K 7.686e-34 0.40
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.347e-33 0.31
LEP_ECOLI lepB Signal peptidase I 1.997e-33 0.44
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 3.102e-33 0.44
EST1_HUMAN CES1 Liver carboxylesterase 1 5.868e-33 0.44
ACHP_LYMST Acetylcholine-binding protein 1.549e-31 0.39
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 2.113e-31 0.42
PHLC_BACCE plc Phospholipase C 4.756e-30 0.31
AMPN_HUMAN ANPEP Aminopeptidase N 9.39e-30 0.35
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 1.223e-29 0.29
CATZ_RAT Ctsz Cathepsin Z 2.203e-29 0.36
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 6.477e-29 0.41
F13A_HUMAN F13A1 Coagulation factor XIII A chain 7.501e-29 0.32
AMPL_HUMAN LAP3 Cytosol aminopeptidase 7.613e-29 0.34
Q3HTL5_PLAFA fp2B Falcipain 2B 1.218e-28 0.35
CBPA1_BOVIN CPA1 Carboxypeptidase A1 4.685e-28 0.34
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 9.336e-28 0.33
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 3.085e-27 0.41
UBP5_HUMAN USP5 Ubiquitin carboxyl-terminal hydrolase 5 5.245e-27 0.33
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 5.768e-27 0.39
BLAT_ECOLX bla; blaT-3; blaT-4; blaT-5; blaT-6 Beta-lactamase TEM 8.739e-27 0.34
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.261e-26 0.34
CAH2_BOVIN CA2 Carbonic anhydrase 2 3.361e-26 0.45
AOFB_RAT Maob Amine oxidase [flavin-containing] B 3.405e-26 0.55
AMPB_RAT Rnpep Aminopeptidase B 3.589e-26 0.30
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 8.902e-26 0.45
Q9NBD4_PLAFA Cysteine protease falcipain-2 1.486e-25 0.31
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 1.641e-25 0.32
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.74e-25 0.39
AMPC_ECOLI ampC Beta-lactamase 3.167e-25 0.34
Q43014_PRUAV Beta-glucosidase 3.865e-25 0.31
PPCE_HUMAN PREP Prolyl endopeptidase 3.89e-25 0.38
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 4.005e-25 0.40
BLAB_BACCE Metallo-beta-lactamase type 2 4.642e-25 0.28
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 5.019e-25 0.35
CASP1_HUMAN CASP1 Caspase-1 8.931e-25 0.38
TRXR1_HUMAN TXNRD1 Thioredoxin reductase 1, cytoplasmic 1.71e-24 0.32
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 1.725e-24 0.33
NAAA_HUMAN NAAA N-acylethanolamine-hydrolyzing acid amidase 2.483e-24 0.35
PERE_HUMAN EPX Eosinophil peroxidase 4.904e-24 0.30
PERE_MOUSE Epx Eosinophil peroxidase 4.904e-24 0.30
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 1.265e-23 0.46
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 1.481e-23 0.49
TGM3L_HUMAN TGM6 Protein-glutamine gamma-glutamyltransferase 6 1.839e-23 0.29
DNLJ_MYCTU ligA DNA ligase A 4.185e-23 0.28
Q7ZJM1_9HIV1 pol Integrase 5.593e-23 0.41
CATJ_RAT Ctsj Cathepsin J 9.993e-23 0.36
Q6RY99_RAT Tetraspanin 1.796e-22 0.32
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 4.481e-22 0.33
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.866e-21 0.41
FABI_BACSU fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 1.885e-21 0.32
AMPN_PIG ANPEP Aminopeptidase N 3.383e-21 0.41
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 4.475e-21 0.39
AMPB_HUMAN RNPEP Aminopeptidase B 5.195e-21 0.30
CRTM_STAAU crtM 4,4'-diapophytoene synthase 8.177e-21 0.31
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 9.806e-21 0.40
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 1.035e-20 0.40
NADE_BACSU nadE NH(3)-dependent NAD(+) synthetase 1.419e-20 0.33
CATK_RABIT CTSK Cathepsin K 1.603e-20 0.37
A5H660_SCHMA HDAC8 Histone deacetylase 8 2.959e-20 0.37
PA_I34A1 PA Polymerase acidic protein 3.385e-20 0.41
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 3.938e-20 0.40
POLG_CXB3N Genome polyprotein 4.09e-20 0.33
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 6.33e-20 0.32
Q4U254_9ENTO protease Protease 1.171e-19 0.46
PA_I000X PA Polymerase acidic protein 1.575e-19 0.38
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 1.705e-19 0.46
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 2.094e-19 0.33
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.183e-19 0.38
RCOR1_HUMAN RCOR1 REST corepressor 1 4.725e-19 0.37
ELNE_HUMAN ELANE Neutrophil elastase 5.311e-19 0.45
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 5.67e-19 0.39
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 5.738e-19 0.33
CATC_RAT Ctsc Dipeptidyl peptidase 1 5.806e-19 0.36
TGM2_MOUSE Tgm2 Protein-glutamine gamma-glutamyltransferase 2 6.741e-19 0.30
AMP1_PLAFQ M1 family aminopeptidase 6.947e-19 0.35
VM1B1_BOTAS Snake venom metalloproteinase BaP1 9.052e-19 0.30
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.315e-18 0.50
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 1.836e-18 0.40
EPHB_MYCTO Epoxide hydrolase B 2.576e-18 0.29
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 3.985e-18 0.34
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 4.432e-18 0.38
NEP_RAT Mme Neprilysin 4.622e-18 0.37
KDM1B_HUMAN KDM1B Lysine-specific histone demethylase 1B 4.879e-18 0.29
HISX_ECOLI hisD Histidinol dehydrogenase 7.502e-18 0.28
NEP_HUMAN MME Neprilysin 8.018e-18 0.33
PPCE_PIG PREP Prolyl endopeptidase 9.964e-18 0.38
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 1.026e-17 0.39
CATS_HUMAN CTSS Cathepsin S 1.186e-17 0.40
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.573e-17 0.45
ACRO_HUMAN ACR Acrosin 1.654e-17 0.38
CAH1_HUMAN CA1 Carbonic anhydrase 1 3.037e-17 0.50
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 4.299e-17 0.42
CAH7_HUMAN CA7 Carbonic anhydrase 7 1.11e-16 0.46
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 1.11e-16 0.35
KCNA2_HUMAN KCNA2 Potassium voltage-gated channel subfamily A member 2 1.11e-16 0.32
KPCA_MOUSE Prkca Protein kinase C alpha type 1.11e-16 0.36
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 1.11e-16 0.42
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 1.11e-16 0.34
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.11e-16 0.41
KYNU_HUMAN KYNU Kynureninase 2.22e-16 0.36
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.22e-16 0.53
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 2.22e-16 0.31
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 3.331e-16 0.43
AMPL_PIG LAP3 Cytosol aminopeptidase 5.551e-16 0.32
CAH14_HUMAN CA14 Carbonic anhydrase 14 5.551e-16 0.46
MYLK_CHICK Mylk Myosin light chain kinase, smooth muscle 5.551e-16 0.30
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 5.551e-16 0.31
H9B8T9_CAPHI CTSB Cathepsin B 6.661e-16 0.42
NEP_MOUSE Mme Neprilysin 6.661e-16 0.35
SENP7_HUMAN SENP7 Sentrin-specific protease 7 6.661e-16 0.47
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 7.772e-16 0.35
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 7.772e-16 0.41
GABT_RAT Abat 4-aminobutyrate aminotransferase, mitochondrial 8.882e-16 0.30
HDAC8_HUMAN HDAC8 Histone deacetylase 8 8.882e-16 0.37
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 8.882e-16 0.38
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 1.332e-15 0.29
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 1.443e-15 0.30
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 1.665e-15 0.36
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 1.776e-15 0.29
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 1.776e-15 0.38
CAH9_HUMAN CA9 Carbonic anhydrase 9 1.998e-15 0.50
FNTA_YEAST RAM2 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 2.442e-15 0.29
PEPA_PIG PGA Pepsin A 2.442e-15 0.33
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 2.554e-15 0.35
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 2.665e-15 0.42
Q6FTL6_CANGA NCE103 Carbonic anhydrase 3.109e-15 0.33
CATL1_BOVIN CTSL Cathepsin L1 3.775e-15 0.38
CASP3_HUMAN CASP3 Caspase-3 4.108e-15 0.38
LY96_HUMAN LY96 Lymphocyte antigen 96 4.441e-15 0.29
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 4.774e-15 0.34
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 5.107e-15 0.30
CAH12_HUMAN CA12 Carbonic anhydrase 12 8.549e-15 0.50
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.41e-14 0.46
ADA33_HUMAN ADAM33 Disintegrin and metalloproteinase domain-containing protein 33 1.543e-14 0.29
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 2.764e-14 0.55
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 4.208e-14 0.33
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 4.863e-14 0.41
MIP_LEGPN mip Outer membrane protein MIP 5.906e-14 0.33
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 5.984e-14 0.50
UROK_HUMAN PLAU Urokinase-type plasminogen activator 5.984e-14 0.39
LUCI_PHOPY Luciferin 4-monooxygenase 6.195e-14 0.38
KCNA3_MOUSE Kcna3 Potassium voltage-gated channel subfamily A member 3 8.515e-14 0.32
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 8.538e-14 0.36
NMT_PLAF7 Glycylpeptide N-tetradecanoyltransferase 1.086e-13 0.40
SSPA_STAAU sspA Glutamyl endopeptidase 1.391e-13 0.37
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.679e-13 0.46
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.752e-13 0.44
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 1.777e-13 0.35
PEPA1_PENJA Penicillopepsin-1 1.884e-13 0.29
AOC3_HUMAN AOC3 Membrane primary amine oxidase 3.311e-13 0.32
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 3.323e-13 0.34
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 3.356e-13 0.44
PDS_SYNE7 pds 15-cis-phytoene desaturase 3.498e-13 0.34
P2RX4_RAT P2rx4 P2X purinoceptor 4 4.932e-13 0.45
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 6.875e-13 0.32
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 7.938e-13 0.32
MGMT_HUMAN MGMT Methylated-DNA--protein-cysteine methyltransferase 1.039e-12 0.33
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 1.039e-12 0.38
STS_HUMAN STS Steryl-sulfatase 1.047e-12 0.33
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 1.13e-12 0.36
CAN_CANAL NCE103 Carbonic anhydrase 1.362e-12 0.33
TYRO_HUMAN TYR Tyrosinase 1.581e-12 0.35
ADH1G_HUMAN ADH1C Alcohol dehydrogenase 1C 2.111e-12 0.30
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 2.238e-12 0.43
BLA2_BACCE blm Metallo-beta-lactamase type 2 2.424e-12 0.36
KLK5_HUMAN KLK5 Kallikrein-5 3.277e-12 0.31
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 3.82e-12 0.30
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 4.708e-12 0.40
POLG_WNV Genome polyprotein 5.097e-12 0.33
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 5.783e-12 0.38
ITPR3_BOVIN ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 6.867e-12 0.38
DYR_RAT Dhfr Dihydrofolate reductase 7.996e-12 0.58
DYR_PNECA Dihydrofolate reductase 1.037e-11 0.58
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 1.187e-11 0.31
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.194e-11 0.36
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.423e-11 0.36
DPP2_HUMAN DPP7 Dipeptidyl peptidase 2 1.449e-11 0.38
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 1.452e-11 0.31
CAH13_MOUSE Ca13 Carbonic anhydrase 13 1.656e-11 0.46
CBS_HUMAN CBS Cystathionine beta-synthase 1.659e-11 0.31
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 1.666e-11 0.33
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 2.186e-11 0.40
KLF5_HUMAN KLF5 Krueppel-like factor 5 2.568e-11 0.38
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 2.695e-11 0.30
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 2.753e-11 0.38
CATG_HUMAN CTSG Cathepsin G 2.83e-11 0.35
LYOX_HUMAN LOX Protein-lysine 6-oxidase 2.914e-11 0.30
CAH3_HUMAN CA3 Carbonic anhydrase 3 2.996e-11 0.39
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 3.012e-11 0.47
Q2PCB5_DICLA ca Carbonic anhydrase 3.542e-11 0.30
FEN1_HUMAN FEN1 Flap endonuclease 1 3.605e-11 0.32
AROK_HELPY aroK Shikimate kinase 5.054e-11 0.35
PADI1_HUMAN PADI1 Protein-arginine deiminase type-1 6.573e-11 0.32
PADI3_HUMAN PADI3 Protein-arginine deiminase type-3 6.573e-11 0.32
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 8.302e-11 0.37
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 8.683e-11 0.34
RS27_HUMAN RPS27 40S ribosomal protein S27 8.878e-11 0.29
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.086e-10 0.36
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.105e-10 0.29
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 1.17e-10 0.35
NEP_RABIT MME Neprilysin 1.245e-10 0.31
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 1.327e-10 0.31
DRTS_TOXGO Bifunctional dihydrofolate reductase-thymidylate synthase 1.372e-10 0.58
USP_DROME usp Protein ultraspiracle 1.545e-10 0.32
Q76353_9HIV1 Integrase 1.637e-10 0.44
AOC3_RAT Aoc3 Membrane primary amine oxidase 1.851e-10 0.32
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 2.014e-10 0.29
PLMN_RAT Plg Plasminogen 2.178e-10 0.30
SC6A3_BOVIN SLC6A3 Sodium-dependent dopamine transporter 2.659e-10 0.30
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 2.663e-10 0.35
AMPD3_HUMAN AMPD3 AMP deaminase 3 2.969e-10 0.32
GRM3_HUMAN GRM3 Metabotropic glutamate receptor 3 3.122e-10 0.36
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 3.195e-10 0.40
LGMN_HUMAN LGMN Legumain 3.308e-10 0.31
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 3.608e-10 0.30
KCNA1_HUMAN KCNA1 Potassium voltage-gated channel subfamily A member 1 3.757e-10 0.32
MOT4_HUMAN SLC16A3 Monocarboxylate transporter 4 3.757e-10 0.32
HDAC1_HUMAN HDAC1 Histone deacetylase 1 4.249e-10 0.46
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 4.735e-10 0.34
S100B_HUMAN S100B Protein S100-B 4.884e-10 0.29
GALR2_RAT Galr2 Galanin receptor type 2 5.162e-10 0.29
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 5.42e-10 0.31
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 5.482e-10 0.38
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 6.559e-10 0.44
KLK1_HUMAN KLK1 Kallikrein-1 7.536e-10 0.36
KMO_RAT Kmo Kynurenine 3-monooxygenase 7.795e-10 0.29
MGLL_HUMAN MGLL Monoglyceride lipase 8.219e-10 0.32
CHLE_HUMAN BCHE Cholinesterase 1.029e-09 0.48
KAT2A_HUMAN KAT2A Histone acetyltransferase KAT2A 1.036e-09 0.33
TRY1_HUMAN PRSS1 Trypsin-1 1.106e-09 0.38
ADH1B_HUMAN ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH1B 1.117e-09 0.30
ECR_BOMMO EcR Ecdysone receptor 1.13e-09 0.32
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 1.273e-09 0.39
MMP2_HUMAN MMP2 72 kDa type IV collagenase 1.349e-09 0.39
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 1.365e-09 0.31
ELAS_PSEAE lasB Elastase 1.477e-09 0.33
CASP9_HUMAN CASP9 Caspase-9 1.529e-09 0.34
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 1.554e-09 0.30
RORA_HUMAN RORA Nuclear receptor ROR-alpha 1.608e-09 0.33
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 1.729e-09 0.54
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.797e-09 0.47
DRTS_PLAFK Bifunctional dihydrofolate reductase-thymidylate synthase 2.123e-09 0.37
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 2.44e-09 0.31
AA3R_RAT Adora3 Adenosine receptor A3 2.471e-09 0.35
Q9SEH8_SOYBN Man1 alpha-1,2-Mannosidase 2.533e-09 0.29
AMPC_PSEAE ampC Beta-lactamase 2.605e-09 0.35
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 2.907e-09 0.32
IMPA1_BOVIN IMPA1 Inositol monophosphatase 1 2.944e-09 0.31
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 3.2e-09 0.31
EST5_RAT Liver carboxylesterase B-1 3.304e-09 0.31
STRP_STRP1 ska Streptokinase A 3.356e-09 0.64
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 3.62e-09 0.32
HDAC2_HUMAN HDAC2 Histone deacetylase 2 3.688e-09 0.35
Q8IL32_PLAF7 Heat shock protein 90, putative 3.73e-09 0.52
HISX_BRUSU hisD Histidinol dehydrogenase 3.808e-09 0.31
ASAH1_HUMAN ASAH1 Acid ceramidase 4.075e-09 0.30
SPP2A_HUMAN SPPL2A Signal peptide peptidase-like 2A 4.166e-09 0.36
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 4.386e-09 0.34
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 4.434e-09 0.45
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 4.599e-09 0.47
CAN2_PIG CAPN2 Calpain-2 catalytic subunit 5.161e-09 0.31
HCAR2_RAT Hcar2 Hydroxycarboxylic acid receptor 2 5.615e-09 0.30
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 6.064e-09 0.36
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 6.492e-09 0.47
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 6.58e-09 0.39
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 7.379e-09 0.35
ACE_HUMAN ACE Angiotensin-converting enzyme 7.976e-09 0.32
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 9.721e-09 0.37
O31048_PORGN DPP IV Dipeptidyl peptidase IV 9.848e-09 0.38
ECR_DROME EcR Ecdysone receptor 1.048e-08 0.32
CAH6_HUMAN CA6 Carbonic anhydrase 6 1.09e-08 0.46
Q53I59_TRYCR PDEC Phosphodiesterase 1.201e-08 0.31
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.397e-08 0.38
IL8_HUMAN CXCL8 Interleukin-8 1.409e-08 0.28
Q49PX0_9POXV N1L N1L 1.428e-08 0.30
TRY1_RAT Prss1 Anionic trypsin-1 1.459e-08 0.30
UPAR_RAT Plaur Urokinase plasminogen activator surface receptor 1.459e-08 0.30
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.674e-08 0.32
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.702e-08 0.39
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 1.808e-08 0.30
ACE_RABIT ACE Angiotensin-converting enzyme 1.942e-08 0.33
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.956e-08 0.34
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 2.146e-08 0.40
THRB_RAT F2 Prothrombin 2.187e-08 0.30
CATL2_HUMAN CTSV Cathepsin L2 2.442e-08 0.33
CTRA_BOVIN Chymotrypsinogen A 2.951e-08 0.36
MIF_HUMAN MIF Macrophage migration inhibitory factor 2.951e-08 0.41
EDNRA_RAT Ednra Endothelin-1 receptor 3.461e-08 0.40
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 3.535e-08 0.35
UPAR_HUMAN PLAUR Urokinase plasminogen activator surface receptor 4.403e-08 0.33
HSF1_MOUSE Hsf1 Heat shock factor protein 1 4.562e-08 0.39
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 5.69e-08 0.31
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 5.975e-08 0.30
DNAB_MYCTU dnaB Replicative DNA helicase 6.037e-08 0.37
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 6.28e-08 0.39
ACES_MOUSE Ache Acetylcholinesterase 6.35e-08 0.31
Q43570_TOBAC NtBBF1.1 Zn finger protein 6.354e-08 0.33
ACMSD_HUMAN ACMSD 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase 6.44e-08 0.29
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 6.889e-08 0.32
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 7.434e-08 0.32
THRB_BOVIN F2 Prothrombin 7.497e-08 0.35
E3UJZ5_SPOLI Ecdysone receptor 8.715e-08 0.32
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 9.822e-08 0.30
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 1e-07 0.30
AOC3_BOVIN AOC3 Membrane primary amine oxidase 1.031e-07 0.29
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 1.16e-07 0.31
TYDP1_HUMAN TDP1 Tyrosyl-DNA phosphodiesterase 1 1.175e-07 0.30
HISX_BRAOC HDH Histidinol dehydrogenase, chloroplastic 1.227e-07 0.28
KPCA_HUMAN PRKCA Protein kinase C alpha type 1.324e-07 0.44
LOX15_PIG ALOX15 Arachidonate 15-lipoxygenase 1.332e-07 0.33
EST1_PIG Liver carboxylesterase 1.342e-07 0.44
O68720_YERPE yopH Targeted effector protein 1.438e-07 0.29
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 1.488e-07 0.34
REV_HV1H2 rev Protein Rev 1.511e-07 0.29
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 1.863e-07 0.32
CAH4_HUMAN CA4 Carbonic anhydrase 4 1.871e-07 0.45
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 1.91e-07 0.30
CAH15_MOUSE Ca15 Carbonic anhydrase 15 2.14e-07 0.33
KAT2B_HUMAN KAT2B Histone acetyltransferase KAT2B 2.192e-07 0.35
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 2.38e-07 0.30
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 2.497e-07 0.40
GSTM2_HUMAN GSTM2 Glutathione S-transferase Mu 2 2.539e-07 0.29
LEG9_HUMAN LGALS9 Galectin-9 2.587e-07 0.33
MMP13_RAT Mmp13 Collagenase 3 2.68e-07 0.28
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 2.707e-07 0.31
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 2.912e-07 0.34
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 3.134e-07 0.32
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 3.187e-07 0.47
ACE_MOUSE Ace Angiotensin-converting enzyme 3.205e-07 0.29
NK1R_CAVPO TACR1 Substance-P receptor 3.326e-07 0.42
HIF1A_HUMAN HIF1A Hypoxia-inducible factor 1-alpha 3.453e-07 0.35
Q8II92_PLAF7 Deoxyuridine 5'-triphosphate nucleotidohydrolase 3.477e-07 0.40
PHOP1_HUMAN PHOSPHO1 Phosphoethanolamine/phosphocholine phosphatase 3.502e-07 0.33
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 3.597e-07 0.31
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 3.597e-07 0.31
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 3.645e-07 0.34
DXR_MYCTU dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3.798e-07 0.33
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 4.317e-07 0.29
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 4.768e-07 0.31
GATA4_MOUSE Gata4 Transcription factor GATA-4 4.905e-07 0.29
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 4.905e-07 0.29
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 5.074e-07 0.40
CBPB1_HUMAN CPB1 Carboxypeptidase B 5.103e-07 0.34
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 5.424e-07 0.30
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 5.452e-07 0.31
CAH4_BOVIN CA4 Carbonic anhydrase 4 5.535e-07 0.38
Q56D28_CAVPO CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells 5.631e-07 0.30
HDAC6_HUMAN HDAC6 Histone deacetylase 6 6.067e-07 0.39
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 6.654e-07 0.34
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 6.784e-07 0.34
PACR_HUMAN ADCYAP1R1 Pituitary adenylate cyclase-activating polypeptide type I receptor 7.308e-07 0.29
POLG_HCV1 Genome polyprotein 8.347e-07 0.38
POLG_DEN2P Genome polyprotein 9.396e-07 0.29
OPRK_RAT Oprk1 Kappa-type opioid receptor 9.8e-07 0.33
RECA_MYCTU recA Protein RecA 1.043e-06 0.33
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 1.135e-06 0.37
PTPRB_HUMAN PTPRB Receptor-type tyrosine-protein phosphatase beta 1.253e-06 0.30
THRB_HUMAN F2 Prothrombin 1.416e-06 0.40
SENP6_HUMAN SENP6 Sentrin-specific protease 6 1.421e-06 0.33
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.6e-06 0.35
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.676e-06 0.42
EIS_MYCTU eis N-acetyltransferase Eis 1.683e-06 0.29
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.683e-06 0.29
Q8JXU8_9HEPC NS5B RNA-directed RNA polymerase 1.702e-06 0.41
PPARG_RAT Pparg Peroxisome proliferator-activated receptor gamma 1.944e-06 0.28
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 2.054e-06 0.33
CMA1_HUMAN CMA1 Chymase 2.102e-06 0.41
TYDP2_HUMAN TDP2 Tyrosyl-DNA phosphodiesterase 2 2.146e-06 0.32
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 2.166e-06 0.35
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.533e-06 0.37
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 2.565e-06 0.32
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 2.606e-06 0.52
CP19A_HUMAN CYP19A1 Aromatase 2.643e-06 0.34
Q9WKE8_9HIV1 reverse transcriptase Reverse transcriptase 2.647e-06 0.33
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 2.849e-06 0.29
NR1H4_MOUSE Nr1h4 Bile acid receptor 3.025e-06 0.30
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 3.119e-06 0.37
NRAM_I77AB Neuraminidase 3.156e-06 0.29
STABP_HUMAN STAMBP STAM-binding protein 3.18e-06 0.32
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 3.203e-06 0.29
CTRC_HUMAN CTRC Chymotrypsin-C 3.296e-06 0.36
CASP1_MOUSE Casp1 Caspase-1 3.398e-06 0.34
P2Y14_MOUSE P2ry14 P2Y purinoceptor 14 4.101e-06 0.35
GBRB_MUSDO Rdl Gamma-aminobutyric acid receptor subunit beta 4.296e-06 0.30
OXDA_PIG DAO D-amino-acid oxidase 4.337e-06 0.32
LPXC_PSEAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 4.357e-06 0.33
NK2R_MESAU TACR2 Substance-K receptor 4.458e-06 0.30
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 4.586e-06 0.30
LEG1_HUMAN LGALS1 Galectin-1 4.725e-06 0.33
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 5.08e-06 0.42
Q9WTR4_RAT Slc6a2 Transporter 5.122e-06 0.34
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 5.327e-06 0.29
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 5.545e-06 0.43
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 5.563e-06 0.32
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 6.278e-06 0.37
GRIA4_RAT Gria4 Glutamate receptor 4 6.365e-06 0.32
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 6.578e-06 0.32
NMBR_HUMAN NMBR Neuromedin-B receptor 6.66e-06 0.30
MMP8_HUMAN MMP8 Neutrophil collagenase 6.772e-06 0.31
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 7.291e-06 0.33
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 7.469e-06 0.35
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 8.153e-06 0.32
GPR55_HUMAN GPR55 G-protein coupled receptor 55 8.282e-06 0.34
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 8.822e-06 0.30
KLK7_HUMAN KLK7 Kallikrein-7 9.328e-06 0.31
DDIT3_MOUSE Ddit3 DNA damage-inducible transcript 3 protein 9.456e-06 0.38
XBP1_HUMAN XBP1 X-box-binding protein 1 9.505e-06 0.39

Eplerenone

MCR_HUMAN NR3C2 Mineralocorticoid receptor 2.143e-05 1.00
Q690N0_BOVIN PGR Progesterone receptor 4.476e-29 0.45
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.186e-27 0.30
SHBG_HUMAN SHBG Sex hormone-binding globulin 3.055e-27 0.34
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 8.971e-14 0.30
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 1.068e-10 0.31
GCR_MOUSE Nr3c1 Glucocorticoid receptor 2.222e-10 0.30
ANDR_RAT Ar Androgen receptor 4.58e-10 0.45
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 4.608e-09 0.28
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 5.04e-08 0.29
ERG2_YEAST ERG2 C-8 sterol isomerase 1.274e-07 0.29
ANDR_MOUSE Ar Androgen receptor 2.339e-07 0.29
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.869e-07 0.28
TAT_HV112 tat Protein Tat 6.919e-07 0.30
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.355e-06 0.28

Trovafloxacin

STRP_STRP1 ska Streptokinase A 3.577e-05 1.00
DDIT3_MOUSE Ddit3 DNA damage-inducible transcript 3 protein 0.004418 1.00
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 0.02729 1.00
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 0.05918 1.00
THAS_HUMAN TBXAS1 Thromboxane-A synthase 0.107 1.00
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 0.3113 1.00
VATB2_HUMAN ATP6V1B2 V-type proton ATPase subunit B, brain isoform 8.178e-60 0.48
Q47245_ECOLX gyrA DNA gyrase subunit A 1.863e-50 0.37
ACEA_MYCTU icl Isocitrate lyase 2.091e-46 0.32
C3SLN2_ECOLX gyrB DNA gyrase subunit B 1.038e-43 0.37
LIPL_HUMAN LPL Lipoprotein lipase 2.898e-18 0.29
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 2.309e-17 0.34
DPO1_THEAQ polA DNA polymerase I, thermostable 1.11e-16 0.33
PARC_STAAU parC DNA topoisomerase 4 subunit A 3.331e-16 0.43
GLYCP_NIPAV G Glycoprotein G 7.772e-15 0.28
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.395e-09 0.30
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 5.067e-09 0.32
DPP4_MOUSE Dpp4 Dipeptidyl peptidase 4 1.576e-07 0.29
GYRA_MYCTU gyrA DNA gyrase subunit A 9.411e-07 0.35
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 3.034e-06 0.32
GYRA_STAAU gyrA DNA gyrase subunit A 4.339e-06 0.43
DPO3_BACSU polC DNA polymerase III PolC-type 5.803e-06 0.35
GYRA_ECOLI gyrA DNA gyrase subunit A 9.226e-06 0.37

Trimipramine

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 4.38e-05 1.00
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 1.259e-44 0.35
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 1.764e-20 0.49
V1AR_RAT Avpr1a Vasopressin V1a receptor 1.833e-20 0.35
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 2.554e-15 0.44
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.424e-12 0.44
PRIO_MESAU PRNP Major prion protein 2.733e-12 0.32
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 3.131e-12 0.44
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 5.222e-12 0.44
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.193e-10 0.43
HRH1_RAT Hrh1 Histamine H1 receptor 1.106e-09 0.44
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.321e-09 0.35
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 2.228e-09 0.43
CAC1S_HUMAN CACNA1S Voltage-dependent L-type calcium channel subunit alpha-1S 1.953e-07 0.30
ACE_HUMAN ACE Angiotensin-converting enzyme 3.254e-07 0.34
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.459e-07 0.44
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.045e-06 0.44
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.723e-06 0.44
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 2.06e-06 0.43
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 4.594e-06 0.44
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 5.06e-06 0.43
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 9.152e-06 0.30

Butoconazole

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.0001437 1.00
Q8IL32_PLAF7 Heat shock protein 90, putative 0.0004125 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.003933 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.005851 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.01744 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.02437 1.00
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 0.03563 1.00
HMOX1_RAT Hmox1 Heme oxygenase 1 3.554e-164 0.59
HMOX2_RAT Hmox2 Heme oxygenase 2 5.101e-71 0.59
THAS_RAT Tbxas1 Thromboxane-A synthase 4.179e-36 0.36
CP121_MYCTU cyp121 Mycocyclosin synthase 1.999e-35 0.44
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 2.293e-33 0.48
CP51A_RAT Cyp51a1 Lanosterol 14-alpha demethylase 1.58e-30 0.34
HMOX1_HUMAN HMOX1 Heme oxygenase 1 2.83e-30 0.38
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 2.41e-28 0.49
A2TEF2_LEIIN CYP51 Putative lanosterol 14-alpha-demethylase 2.614e-25 0.31
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 4.854e-25 0.44
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 8.372e-23 0.44
CP74A_ARATH CYP74A Allene oxide synthase, chloroplastic 3.022e-20 0.32
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 1.081e-19 0.48
CP51_CANAL ERG11 Lanosterol 14-alpha demethylase 1.335e-19 0.31
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 5.544e-19 0.33
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 1.147e-17 0.44
THAS_HUMAN TBXAS1 Thromboxane-A synthase 3.848e-17 0.47
CPXA_PSEPU camC Camphor 5-monooxygenase 1.11e-16 0.32
CP19A_RAT Cyp19a1 Aromatase 5.107e-15 0.33
CP19A_HUMAN CYP19A1 Aromatase 5.362e-14 0.48
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 1.02e-13 0.44
TRPC6_MOUSE Trpc6 Short transient receptor potential channel 6 7.039e-13 0.35
QPCT_HUMAN QPCT Glutaminyl-peptide cyclotransferase 2.426e-07 0.37
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 5.272e-07 0.44
GPBAR_MOUSE Gpbar1 G-protein coupled bile acid receptor 1 8.896e-06 0.34

Moricizine

CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.0002597 1.00
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 3.392e-170 0.73
Q03732_HBV HBcAg Capsid protein 1.645e-56 0.33
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 2.367e-44 0.34
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 1.641e-43 0.32
CASR_HUMAN CASR Extracellular calcium-sensing receptor 8.106e-40 0.35
TERT_HUMAN TERT Telomerase reverse transcriptase 4.029e-35 0.38
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 8.168e-32 0.36
CHLE_HUMAN BCHE Cholinesterase 1.738e-28 0.53
NK2R_HUMAN TACR2 Substance-K receptor 2.148e-27 0.34
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 5.502e-27 0.38
TSHR_HUMAN TSHR Thyrotropin receptor 1.192e-25 0.34
LYSC1_RAT Lyz1 Lysozyme C-1 1.342e-24 0.30
TSHB_BOVIN TSHB Thyrotropin subunit beta 1.125e-20 0.33
NOX1_HUMAN NOX1 NADPH oxidase 1 3.845e-20 0.48
AUKBA_XENLA aurkb-a Aurora kinase B-A 2.322e-19 0.31
5HT2B_MOUSE Htr2b 5-hydroxytryptamine receptor 2B 2.621e-19 0.29
KDM1B_HUMAN KDM1B Lysine-specific histone demethylase 1B 2.621e-19 0.31
BGLR_RAT Gusb Beta-glucuronidase 4.682e-19 0.30
EBPL_HUMAN EBPL Emopamil-binding protein-like 4.682e-19 0.30
CNR1_RAT Cnr1 Cannabinoid receptor 1 4.272e-18 0.35
ADCY5_RAT Adcy5 Adenylate cyclase type 5 5.336e-18 0.33
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 2.218e-17 0.36
DPO3_BACSU polC DNA polymerase III PolC-type 2.986e-14 0.34
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 5.496e-14 0.29
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 5.496e-14 0.29
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 5.496e-14 0.29
PRKDC_HUMAN PRKDC DNA-dependent protein kinase catalytic subunit 2.136e-13 0.37
MK14_MOUSE Mapk14 Mitogen-activated protein kinase 14 3.275e-13 0.30
5HT2A_MOUSE Htr2a 5-hydroxytryptamine receptor 2A 1.482e-12 0.28
THB_HUMAN THRB Thyroid hormone receptor beta 3.804e-12 0.34
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 9.956e-12 0.37
HSP12_CAEEL hsp-16.2 Heat shock protein Hsp-16.2 1.199e-11 0.34
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 1.377e-11 0.30
CALM_BOVIN CALM Calmodulin 2.873e-11 0.30
TRPV4_MOUSE Trpv4 Transient receptor potential cation channel subfamily V member 4 3.108e-11 0.33
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 3.225e-11 0.31
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 3.785e-11 0.39
HSPB1_HUMAN HSPB1 Heat shock protein beta-1 7.655e-11 0.29
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.656e-10 0.31
CNR2_HUMAN CNR2 Cannabinoid receptor 2 3.479e-10 0.38
DRD3_HUMAN DRD3 D(3) dopamine receptor 3.998e-10 0.42
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 4.287e-10 0.29
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 5.366e-10 0.36
Q3Y5H1_9GAMC 3C-like protease 7.319e-10 0.30
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 8.03e-10 0.29
CDKL3_HUMAN CDKL3 Cyclin-dependent kinase-like 3 9.309e-10 0.28
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 1.193e-09 0.29
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 1.496e-09 0.30
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 4.372e-09 0.28
G3I1B6_CRIGR 5-hydroxytryptamine receptor 4.541e-09 0.33
HRH1_HUMAN HRH1 Histamine H1 receptor 4.609e-09 0.42
CCKAR_RAT Cckar Cholecystokinin receptor type A 5.263e-09 0.36
CNR1_HUMAN CNR1 Cannabinoid receptor 1 5.291e-09 0.35
5HT1B_CRIGR HTR1B 5-hydroxytryptamine receptor 1B 5.78e-09 0.33
MK15_HUMAN MAPK15 Mitogen-activated protein kinase 15 6.701e-09 0.29
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 6.871e-09 0.39
5HT2C_MOUSE Htr2c 5-hydroxytryptamine receptor 2C 8.815e-09 0.29
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 1.053e-08 0.29
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.285e-08 0.32
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 1.308e-08 0.34
SCRB1_HUMAN SCARB1 Scavenger receptor class B member 1 1.424e-08 0.29
CALM1_HUMAN CALM1 Calmodulin-1 1.462e-08 0.30
CHLE_HORSE BCHE Cholinesterase 1.541e-08 0.41
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 1.612e-08 0.29
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 1.698e-08 0.35
KLK6_HUMAN KLK6 Kallikrein-6 1.968e-08 0.30
HKDC1_HUMAN HKDC1 Hexokinase HKDC1 2.421e-08 0.33
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 3.532e-08 0.29
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 3.532e-08 0.29
MET_HUMAN MET Hepatocyte growth factor receptor 4.009e-08 0.40
FNTA_HUMAN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 4.508e-08 0.34
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 4.728e-08 0.28
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 6.236e-08 0.34
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 6.465e-08 0.39
DRD2_HUMAN DRD2 D(2) dopamine receptor 6.532e-08 0.38
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 6.834e-08 0.33
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 7.139e-08 0.42
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 7.153e-08 0.29
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 7.733e-08 0.42
SOAT1_HUMAN SOAT1 Sterol O-acyltransferase 1 8.574e-08 0.29
ACES_HUMAN ACHE Acetylcholinesterase 9.185e-08 0.39
CTRO_HUMAN CIT Citron Rho-interacting kinase 9.923e-08 0.29
NLK_HUMAN NLK Serine/threonine-protein kinase NLK 9.923e-08 0.29
NK2R_CAVPO TACR2 Substance-K receptor 9.989e-08 0.29
LIPL_RAT Lpl Lipoprotein lipase 1.031e-07 0.29
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 1.033e-07 0.30
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 1.187e-07 0.34
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 1.212e-07 0.28
MYO3A_HUMAN MYO3A Myosin-IIIa 1.212e-07 0.28
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 1.826e-07 0.29
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 1.826e-07 0.29
AURKB_HUMAN AURKB Aurora kinase B 2.001e-07 0.31
ATM_HUMAN ATM Serine-protein kinase ATM 2.108e-07 0.41
NPBW1_HUMAN NPBWR1 Neuropeptides B/W receptor type 1 2.188e-07 0.42
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 2.222e-07 0.35
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 2.427e-07 0.29
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 2.753e-07 0.28
MYO3B_HUMAN MYO3B Myosin-IIIb 2.753e-07 0.28
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 2.941e-07 0.33
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 3.186e-07 0.29
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 5.311e-07 0.29
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 8.573e-07 0.42
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 8.843e-07 0.31
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 8.948e-07 0.31
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 1.08e-06 0.28
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 1.553e-06 0.31
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 1.665e-06 0.38
CDK19_HUMAN CDK19 Cyclin-dependent kinase 19 1.877e-06 0.30
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 1.924e-06 0.28
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 1.924e-06 0.28
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 2.165e-06 0.29
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 2.675e-06 0.33
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 3.082e-06 0.34
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 3.24e-06 0.28
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 3.31e-06 0.28
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 3.597e-06 0.28
MMP13_BOVIN MMP13 Collagenase 3 3.723e-06 0.34
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 4.092e-06 0.29
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 4.84e-06 0.29
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 5.135e-06 0.33
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 5.202e-06 0.28
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 5.694e-06 0.29
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 6.145e-06 0.33
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 7.088e-06 0.36
GPR55_HUMAN GPR55 G-protein coupled receptor 55 7.401e-06 0.34
INSRR_HUMAN INSRR Insulin receptor-related protein 8.016e-06 0.28
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 8.016e-06 0.28
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 8.016e-06 0.28
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 8.051e-06 0.31
DRD4_MOUSE Drd4 D(4) dopamine receptor 8.684e-06 0.28
PCNA_HUMAN PCNA Proliferating cell nuclear antigen 8.695e-06 0.29
PTN5_HUMAN PTPN5 Tyrosine-protein phosphatase non-receptor type 5 9.533e-06 0.34

Dextropropoxyphene

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.01001 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.6631 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.942 1.00
AMYP_RAT Amy2 Pancreatic alpha-amylase 6.377e-40 0.32
UBC12_HUMAN UBE2M NEDD8-conjugating enzyme Ubc12 6.705e-36 0.28
Q704V1_PSEAI blaGIM-1 GIM-1 protein 7.04e-23 0.28
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 1.957e-18 0.29
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 5.247e-18 0.31
CBPA1_HUMAN CPA1 Carboxypeptidase A1 1.12e-17 0.33
THER_BACTH npr Thermolysin 5.551e-16 0.30
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 7.216e-15 0.30
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 8.327e-15 0.31
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 1.001e-12 0.31
CATL1_BOVIN CTSL Cathepsin L1 1.595e-12 0.29
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 8.274e-12 0.33
NK3R_CAVPO TACR3 Neuromedin-K receptor 1.125e-11 0.30
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 9.795e-11 0.30
PHLC_BACCE plc Phospholipase C 1.295e-10 0.31
NK3R_HUMAN TACR3 Neuromedin-K receptor 3.965e-09 0.32
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 5.647e-09 0.32
PAPA1_CARPA Papain 6.638e-08 0.29
ERG2_YEAST ERG2 C-8 sterol isomerase 8.445e-08 0.30
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 8.227e-07 0.29
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.082e-06 0.30
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 2.029e-06 0.30
KLK5_HUMAN KLK5 Kallikrein-5 3.133e-06 0.28
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 3.563e-06 0.28
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 4.807e-06 0.30
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 5.719e-06 0.28
Q72874_9HIV1 pol Pol polyprotein 6.527e-06 0.32
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 7.135e-06 0.31
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 8.198e-06 0.30

Phentolamine

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.07428 1.00
NISCH_RAT Nisch Nischarin 1.385e-62 0.38
NISCH_HUMAN NISCH Nischarin 1.521e-40 0.39
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 6.918e-32 0.57
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 2.847e-31 0.57
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 9.25e-28 0.57
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 2.898e-27 0.57
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 6.901e-27 0.57
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 7.487e-23 0.57
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 1.778e-21 0.74
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 1.521e-14 0.32
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 4.623e-11 0.32
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 8.293e-10 0.31
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 7.035e-07 0.45
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 8.997e-07 0.45
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 1.308e-06 0.54

Amphotericin_B

CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 0.09982 1.00

Mitotane

ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.1002 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.3436 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.4773 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.4777 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.6304 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.9804 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 0.9869 1.00
CP19A_RAT Cyp19a1 Aromatase 2.37e-13 0.33
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 7.893e-07 0.29
FFAR2_HUMAN FFAR2 Free fatty acid receptor 2 1.685e-06 0.31

Nicergoline

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.1542 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.8357 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.9116 1.00

Methoxamine

ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 0.1546 1.00
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 3.433e-57 0.50
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 8.245e-39 0.30
Q49PX0_9POXV N1L N1L 3.688e-35 0.37
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 1.844e-26 0.38
TPPP_BOVIN TPPP Tubulin polymerization-promoting protein 9.886e-26 0.32
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 2.818e-25 0.41
CYSP_PLAFA Trophozoite cysteine proteinase 5.065e-24 0.31
SO1C1_MOUSE Slco1c1 Solute carrier organic anion transporter family member 1C1 4.633e-23 0.28
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.058e-20 0.50
DYR_ECOLI folA Dihydrofolate reductase 2.037e-20 0.30
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 2.438e-20 0.31
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 4.094e-19 0.30
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 4.329e-18 0.33
KAT3_HUMAN KYAT3 Kynurenine--oxoglutarate transaminase 3 4.879e-18 0.29
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.71e-17 0.36
DYR_CANAX DFR1 Dihydrofolate reductase 1.11e-16 0.45
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 3.331e-16 0.36
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 6.783e-14 0.38
DYR_YEAST DFR1 Dihydrofolate reductase 1.449e-12 0.30
Q81R22_BACAN dfrA Dihydrofolate reductase 1.723e-12 0.30
THB_RAT Thrb Thyroid hormone receptor beta 9.635e-12 0.36
DYR_RAT Dhfr Dihydrofolate reductase 1.127e-11 0.34
ADA2B_RAT Adra2b Alpha-2B adrenergic receptor 1.3e-11 0.63
DRTS_TOXGO Bifunctional dihydrofolate reductase-thymidylate synthase 2.105e-11 0.35
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 9.671e-11 0.35
HCD2_HUMAN HSD17B10 3-hydroxyacyl-CoA dehydrogenase type-2 1.336e-10 0.28
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.707e-10 0.57
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 2.749e-10 0.32
DYR_HUMAN DHFR Dihydrofolate reductase 7.639e-10 0.45
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 8.896e-10 0.36
TSPO_HUMAN TSPO Translocator protein 1.877e-09 0.30
MOT4_HUMAN SLC16A3 Monocarboxylate transporter 4 2.406e-09 0.29
AOC3_HUMAN AOC3 Membrane primary amine oxidase 2.454e-09 0.37
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 3.009e-09 0.35
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 3.742e-09 0.32
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 5.124e-09 0.32
DYR_PNECA Dihydrofolate reductase 6.094e-09 0.32
RENI_CALJA REN Renin 8.251e-09 0.29
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.016e-08 0.32
Q9UUP5_PNEJI DHFR DHFR 1.813e-08 0.28
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 2.89e-08 0.31
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 3.985e-08 0.29
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 7.707e-08 0.29
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 8.63e-08 0.33
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 1.647e-07 0.29
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 1.831e-07 0.62
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 2.378e-07 0.33
CAH13_MOUSE Ca13 Carbonic anhydrase 13 2.815e-07 0.32
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 3.378e-07 0.30
CAH15_MOUSE Ca15 Carbonic anhydrase 15 3.719e-07 0.32
Q43570_TOBAC NtBBF1.1 Zn finger protein 4.268e-07 0.29
EST1_RABIT Liver carboxylesterase 1 6.276e-07 0.31
KS6B2_HUMAN RPS6KB2 Ribosomal protein S6 kinase beta-2 7.518e-07 0.29
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 8.973e-07 0.63
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 9.062e-07 0.46
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 1.13e-06 0.33
Q9S446_STAAU srtA Class A sortase SrtA 1.184e-06 0.34
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 1.46e-06 0.34
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.683e-06 0.29
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.879e-06 0.32
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 2.048e-06 0.38
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.185e-06 0.29
NCOA1_HUMAN NCOA1 Nuclear receptor coactivator 1 2.349e-06 0.31
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 3.852e-06 0.38
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 4.858e-06 0.37
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 5.277e-06 0.34
LUCI_AQULA Luciferin 4-monooxygenase 6.347e-06 0.29
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 6.574e-06 0.33
DYR_STAAU folA Dihydrofolate reductase 7.783e-06 0.31

Pemetrexed

TYSY_MOUSE Tyms Thymidylate synthase 7.555e-267 0.77
PUR2_HUMAN GART Trifunctional purine biosynthetic protein adenosine-3 4.686e-246 0.77
DYR_MOUSE Dhfr Dihydrofolate reductase 4.312e-172 0.77
FOLR1_HUMAN FOLR1 Folate receptor alpha 2.043e-166 0.77
PUR2_MOUSE Gart Trifunctional purine biosynthetic protein adenosine-3 2.199e-158 0.56
PCFT_HUMAN SLC46A1 Proton-coupled folate transporter 8.841e-157 0.77
TYSY_HUMAN TYMS Thymidylate synthase 1.107e-146 0.69
FOLR2_HUMAN FOLR2 Folate receptor beta 2.241e-139 0.77
FOLC_HUMAN FPGS Folylpolyglutamate synthase, mitochondrial 5.323e-128 0.42
DYR_ENTFC folA Dihydrofolate reductase 2.778e-125 0.52
S19A1_HUMAN SLC19A1 Reduced folate transporter 4.15e-125 0.77
DYR_LACCA folA Dihydrofolate reductase 5.453e-101 0.77
FOLC_MOUSE Fpgs Folylpolyglutamate synthase, mitochondrial 3.302e-100 0.52
TYSY_RAT Tyms Thymidylate synthase 1.809e-94 0.69
DYR_HUMAN DHFR Dihydrofolate reductase 2.688e-89 0.77
E2QDN0_ECOLX thyA Thymidylate synthase 9.33e-78 0.51
SO1A3_RAT Slco1a3 Solute carrier organic anion transporter family member 1A3 5.785e-77 0.44
TYSY_LACCA thyA Thymidylate synthase 2.899e-67 0.77
METH_HUMAN MTR Methionine synthase 1.814e-63 0.37
FOLC_ECOLI folC Dihydrofolate synthase/folylpolyglutamate synthase 7.865e-58 0.46
MTDC_HUMAN MTHFD2 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial 2.086e-56 0.45
Q9I056_PSEAE cpg2 Carboxypeptidase G2 4.868e-56 0.34
MMP12_HUMAN MMP12 Macrophage metalloelastase 7.069e-48 0.34
MMP10_HUMAN MMP10 Stromelysin-2 7.213e-48 0.33
GGH_HUMAN GGH Gamma-glutamyl hydrolase 1.104e-46 0.30
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 1.652e-46 0.35
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 7.399e-39 0.41
C3SWJ7_ECOLX thyA Thymidylate synthase 1.21e-38 0.77
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 2.377e-38 0.37
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 4.044e-35 0.33
DYR_MYCTU folA Dihydrofolate reductase 4.518e-35 0.40
DYR_RAT Dhfr Dihydrofolate reductase 9.381e-35 0.54
HMGB1_HUMAN HMGB1 High mobility group protein B1 3.098e-32 0.40
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 1.006e-28 0.69
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 6.087e-26 0.36
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 2.307e-24 0.36
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 1.16e-23 0.48
DRTS_TOXGO Bifunctional dihydrofolate reductase-thymidylate synthase 4.421e-23 0.77
MMP8_HUMAN MMP8 Neutrophil collagenase 1.08e-21 0.33
DYR_CHICK DHFR Dihydrofolate reductase 1.183e-20 0.40
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 1.282e-20 0.31
RICI_RICCO Ricin 2.025e-20 0.33
RIR1_MYCTU nrdE Ribonucleoside-diphosphate reductase subunit alpha 1.075e-19 0.31
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.193e-19 0.31
LY96_HUMAN LY96 Lymphocyte antigen 96 1.11e-16 0.32
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 7.427e-14 0.32
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 2.187e-13 0.32
DYR_PNECA Dihydrofolate reductase 3.296e-13 0.69
BODG_PSESK Gamma-butyrobetaine dioxygenase 4.673e-13 0.28
DYR_BOVIN DHFR Dihydrofolate reductase 8.881e-13 0.40
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 1.767e-12 0.36
DLG4_HUMAN DLG4 Disks large homolog 4 1.353e-11 0.29
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 1.552e-11 0.31
Q81R22_BACAN dfrA Dihydrofolate reductase 1.64e-11 0.41
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 8.856e-11 0.65
TYSY_ECOLI thyA Thymidylate synthase 4.103e-10 0.49
PADI2_HUMAN PADI2 Protein-arginine deiminase type-2 7.541e-10 0.29
MMP2_HUMAN MMP2 72 kDa type IV collagenase 1.037e-09 0.34
MMP13_HUMAN MMP13 Collagenase 3 1.175e-09 0.34
PNPH_BOVIN PNP Purine nucleoside phosphorylase 7.373e-09 0.30
CAH4_BOVIN CA4 Carbonic anhydrase 4 9.631e-09 0.44
ENTK_HUMAN TMPRSS15 Enteropeptidase 2.339e-08 0.33
CCKAR_RAT Cckar Cholecystokinin receptor type A 3.38e-08 0.32
DRTS_LEIMA Bifunctional dihydrofolate reductase-thymidylate synthase 3.392e-08 0.40
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 1.883e-07 0.32
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 6.864e-07 0.34
CAH2_HUMAN CA2 Carbonic anhydrase 2 8.837e-07 0.44
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 4.256e-06 0.29
PTR1_LEIMA PTR1 Pteridine reductase 1 4.96e-06 0.40
PNPH_RAT Pnp Purine nucleoside phosphorylase 5.463e-06 0.28

Nafarelin

MC5R_MOUSE Mc5r Melanocortin receptor 5 4.858e-234 0.47
NTR2_HUMAN NTSR2 Neurotensin receptor type 2 3.551e-204 0.48
MC4R_MOUSE Mc4r Melanocortin receptor 4 4.166e-200 0.47
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 1.367e-196 0.52
MC3R_MOUSE Mc3r Melanocortin receptor 3 3.761e-185 0.47
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 1.044e-170 0.47
MC3R_HUMAN MC3R Melanocortin receptor 3 3.554e-170 0.52
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 9.212e-159 0.44
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 3.833e-153 0.57
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 4.479e-147 0.50
GRPR_MOUSE Grpr Gastrin-releasing peptide receptor 2.454e-132 0.40
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 1.034e-129 0.50
CD36_RAT Cd36 Platelet glycoprotein 4 2.412e-128 0.41
OPRM_RAT Oprm1 Mu-type opioid receptor 2.577e-115 0.53
NTR1_RAT Ntsr1 Neurotensin receptor type 1 4.659e-113 0.47
MC4R_HUMAN MC4R Melanocortin receptor 4 7.805e-111 0.52
RENI_RAT Ren1 Renin 2.222e-110 0.44
Q9R297_RAT Mlnr Motilin receptor 2.215e-108 0.43
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 3.88e-107 0.46
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 3.453e-93 0.50
OPRD_RAT Oprd1 Delta-type opioid receptor 2.474e-88 0.50
GASR_BOVIN CCKBR Gastrin/cholecystokinin type B receptor 6.158e-88 0.33
RENI_HUMAN REN Renin 2.753e-87 0.49
KISSR_HUMAN KISS1R KiSS-1 receptor 7.215e-86 0.48
SORT_HUMAN SORT1 Sortilin 3.613e-84 0.46
OPRM_CAVPO OPRM1 Mu-type opioid receptor 6.018e-83 0.54
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.165e-82 0.53
TRFR_HUMAN TRHR Thyrotropin-releasing hormone receptor 2.762e-81 0.43
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 1.548e-80 0.43
PAR2_HUMAN F2RL1 Proteinase-activated receptor 2 1.798e-80 0.36
GRPR_RAT Grpr Gastrin-releasing peptide receptor 2.455e-77 0.47
F1SH20_PIG TRHDE Uncharacterized protein 1.575e-75 0.38
QRFPR_HUMAN QRFPR Pyroglutamylated RF-amide peptide receptor 1.679e-73 0.36
TRFR_MOUSE Trhr Thyrotropin-releasing hormone receptor 6.723e-71 0.43
TETX_CLOTE tetX Tetanus toxin 1.695e-70 0.35
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 1.108e-66 0.43
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 2.717e-66 0.38
MMP11_MOUSE Mmp11 Stromelysin-3 8.339e-66 0.34
Q9ERT1_MOUSE TRH-R2 Thyrotropin-releasing hormone receptor 2 1.373e-64 0.43
TRFR_RAT Trhr Thyrotropin-releasing hormone receptor 3.342e-63 0.43
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 1.504e-62 0.54
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 5.937e-62 0.40
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 3.2e-58 0.38
SURA_ECOLI surA Chaperone SurA 2.742e-57 0.46
NMUR1_MOUSE Nmur1 Neuromedin-U receptor 1 1.708e-56 0.45
PEPC_HUMAN PGC Gastricsin 2.096e-56 0.32
NPFF2_RAT Npffr2 Neuropeptide FF receptor 2 3.193e-56 0.36
FURIN_HUMAN FURIN Furin 2.02e-55 0.41
EDNRA_MOUSE Ednra Endothelin-1 receptor 2.292e-55 0.39
RENI1_MOUSE Ren1 Renin-1 2.246e-54 0.32
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 3.91e-53 0.46
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.345e-51 0.40
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 2.995e-51 0.37
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 3.547e-48 0.39
TRY1_BOVIN Cationic trypsin 1.867e-47 0.41
CCKAR_MOUSE Cckar Cholecystokinin receptor type A 2.373e-46 0.39
EDNRB_RAT Ednrb Endothelin receptor type B 6.374e-46 0.50
FSHR_RAT Fshr Follicle-stimulating hormone receptor 7.455e-46 0.57
SSR2_MOUSE Sstr2 Somatostatin receptor type 2 9.114e-46 0.31
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 1.104e-45 0.43
NRP1_RAT Nrp1 Neuropilin-1 5.014e-43 0.52
Q5D7U5_CHICK OXTR Oxytocin-like receptor 9.555e-42 0.33
CCKAR_RAT Cckar Cholecystokinin receptor type A 5.167e-41 0.38
NK1R_CAVPO TACR1 Substance-P receptor 1.685e-40 0.40
FPRS1_MOUSE Fpr-s1 Formyl peptide receptor-related sequence 1 6.618e-40 0.28
NK1R_RAT Tacr1 Substance-P receptor 8.055e-40 0.52
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 2.709e-39 0.31
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 2.709e-39 0.31
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.546e-38 0.32
NMBR_HUMAN NMBR Neuromedin-B receptor 4.925e-38 0.41
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 9.421e-38 0.42
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 3.793e-37 0.39
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 2.745e-36 0.43
CATE_HUMAN CTSE Cathepsin E 3.772e-36 0.33
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 5.058e-36 0.46
G1FEK8_9CALI Protease 6.89e-36 0.28
I1U3K2_9CALI POL Nonstructural polyprotein 6.89e-36 0.28
ECE1_BOVIN ECE1 Endothelin-converting enzyme 1 1.743e-35 0.29
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 2.114e-35 0.47
THRB_HUMAN F2 Prothrombin 2.615e-35 0.48
NK2R_MESAU TACR2 Substance-K receptor 3.776e-35 0.38
MBOA4_HUMAN MBOAT4 Ghrelin O-acyltransferase 4.873e-35 0.28
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 9.453e-35 0.34
MC5R_HUMAN MC5R Melanocortin receptor 5 4.269e-34 0.44
PEPA_PIG PGA Pepsin A 6.898e-34 0.46
IDE_HUMAN IDE Insulin-degrading enzyme 1.161e-33 0.45
Q8I6Z5_PLAF7 Plasmepsin V 2.038e-33 0.34
NPY4R_HUMAN NPY4R Neuropeptide Y receptor type 4 4.688e-33 0.35
PGTB1_RAT Pggt1b Geranylgeranyl transferase type-1 subunit beta 8.132e-33 0.41
BRCA1_HUMAN BRCA1 Breast cancer type 1 susceptibility protein 1.795e-31 0.35
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 6.759e-31 0.42
OPRK_RAT Oprk1 Kappa-type opioid receptor 5.393e-29 0.48
MMP11_HUMAN MMP11 Stromelysin-3 5.771e-29 0.28
MAGI3_HUMAN MAGI3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 1.139e-28 0.35
OPRD_HUMAN OPRD1 Delta-type opioid receptor 2.647e-28 0.53
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 1.402e-26 0.43
NMBR_RAT Nmbr Neuromedin-B receptor 3.954e-26 0.32
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 4.176e-26 0.34
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 8.505e-26 0.43
CARP_YEAST PEP4 Saccharopepsin 2.258e-25 0.31
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 2.28e-25 0.43
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 4.056e-25 0.40
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 7.492e-25 0.37
CATZ_RAT Ctsz Cathepsin Z 1.106e-24 0.30
HEPS_HUMAN HPN Serine protease hepsin 6.392e-24 0.43
MMP8_HUMAN MMP8 Neutrophil collagenase 1.298e-23 0.34
A4HSF7_LEIIN TRYR Trypanothione reductase 3.406e-23 0.28
ELAS_PSEAE lasB Elastase 3.511e-23 0.34
CBX7_HUMAN CBX7 Chromobox protein homolog 7 3.841e-23 0.37
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 4.596e-23 0.51
NK3R_CAVPO TACR3 Neuromedin-K receptor 6.615e-23 0.38
CP125_MYCTU cyp125 Steroid C26-monooxygenase 7.566e-23 0.28
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.837e-22 0.54
CFAB_HUMAN CFB Complement factor B 6.302e-22 0.41
SYMC_HUMAN MARS1 Methionine--tRNA ligase, cytoplasmic 7.054e-22 0.31
AMPN_HUMAN ANPEP Aminopeptidase N 2.863e-21 0.43
TMPS2_HUMAN TMPRSS2 Transmembrane protease serine 2 4.714e-21 0.34
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 1.915e-20 0.43
OXYR_MOUSE Oxtr Oxytocin receptor 2.869e-20 0.32
OXYR_HUMAN OXTR Oxytocin receptor 3.497e-20 0.36
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 6.41e-20 0.36
VM1B1_BOTAS Snake venom metalloproteinase BaP1 9.022e-20 0.31
OPRM_MOUSE Oprm1 Mu-type opioid receptor 1.228e-19 0.48
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 1.332e-19 0.32
TYRO_HUMAN TYR Tyrosinase 1.694e-19 0.34
EDNRA_PIG EDNRA Endothelin-1 receptor 2.195e-19 0.35
PAR1_HUMAN F2R Proteinase-activated receptor 1 2.55e-19 0.37
CATJ_RAT Ctsj Cathepsin J 4.035e-19 0.30
RIR1_MYCTU nrdE Ribonucleoside-diphosphate reductase subunit alpha 4.884e-19 0.30
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 8.026e-19 0.34
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 1.183e-18 0.38
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 2.986e-18 0.32
NEC2_HUMAN PCSK2 Neuroendocrine convertase 2 4.879e-18 0.29
GRIA1_RAT Gria1 Glutamate receptor 1 6.134e-18 0.32
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 9.067e-18 0.36
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 1.597e-17 0.53
NK2R_RAT Tacr2 Substance-K receptor 2.121e-17 0.37
EDNRA_HUMAN EDNRA Endothelin-1 receptor 2.829e-17 0.44
CTRL_HUMAN CTRL Chymotrypsin-like protease CTRL-1 2.22e-16 0.29
NK2R_RABIT TACR2 Substance-K receptor 4.441e-16 0.37
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 4.441e-16 0.48
CATC_RAT Ctsc Dipeptidyl peptidase 1 5.551e-16 0.30
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 6.661e-16 0.37
MMP2_HUMAN MMP2 72 kDa type IV collagenase 1.776e-15 0.34
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 5.773e-15 0.28
PCSK6_HUMAN PCSK6 Proprotein convertase subtilisin/kexin type 6 6.661e-15 0.31
FNTB_RAT Fntb Protein farnesyltransferase subunit beta 1.499e-14 0.44
FNTA_RAT Fnta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 1.943e-14 0.44
NK1R_HUMAN TACR1 Substance-P receptor 2.198e-14 0.53
B3DH72_DANRE oprd1b Opioid receptor, delta 1b 3.975e-14 0.35
O57585_DANRE oprd1a Opioid receptor homologue 3.975e-14 0.35
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 4.818e-14 0.35
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 8.382e-14 0.36
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 8.571e-14 0.34
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 9.159e-14 0.38
ENV_HV1H2 env Envelope glycoprotein gp160 1.091e-13 0.30
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 2.068e-13 0.38
V2R_PIG AVPR2 Vasopressin V2 receptor 2.442e-13 0.34
NEP_RABIT MME Neprilysin 2.504e-13 0.30
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 3.066e-13 0.30
PCSK7_HUMAN PCSK7 Proprotein convertase subtilisin/kexin type 7 3.922e-13 0.29
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 5.04e-13 0.34
ADA12_HUMAN ADAM12 Disintegrin and metalloproteinase domain-containing protein 12 6.108e-13 0.28
CTRC_HUMAN CTRC Chymotrypsin-C 6.515e-13 0.33
ACE_HUMAN ACE Angiotensin-converting enzyme 7.226e-13 0.50
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 7.658e-13 0.35
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 8.916e-13 0.35
CCNA2_HUMAN CCNA2 Cyclin-A2 1.309e-12 0.46
PLMN_HUMAN PLG Plasminogen 1.56e-12 0.36
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 2.123e-12 0.29
GRPR_HUMAN GRPR Gastrin-releasing peptide receptor 2.804e-12 0.41
MMP1_HUMAN MMP1 Interstitial collagenase 2.969e-12 0.34
EDNRA_RAT Ednra Endothelin-1 receptor 4.784e-12 0.36
NTR2_RAT Ntsr2 Neurotensin receptor type 2 9.287e-12 0.46
ACE_RAT Ace Angiotensin-converting enzyme 1.058e-11 0.30
OXYR_RAT Oxtr Oxytocin receptor 1.726e-11 0.35
Q91H74_9FLAV Genome polyprotein 2.937e-11 0.35
TRY3_HUMAN PRSS3 Trypsin-3 3.754e-11 0.30
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 3.956e-11 0.30
V1AR_RAT Avpr1a Vasopressin V1a receptor 5.524e-11 0.35
O68720_YERPE yopH Targeted effector protein 5.647e-11 0.29
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 6.404e-11 0.32
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 8.357e-11 0.34
PPCE_MOUSE Prep Prolyl endopeptidase 8.581e-11 0.29
GHSR_RAT Ghsr Growth hormone secretagogue receptor type 1 8.724e-11 0.33
PRTN3_HUMAN PRTN3 Myeloblastin 1.38e-10 0.31
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.721e-10 0.33
V1BR_RAT Avpr1b Vasopressin V1b receptor 1.915e-10 0.35
MCA2_TRYBB MCA2 Metacaspase 2.029e-10 0.30
ITB1_HUMAN ITGB1 Integrin beta-1 2.726e-10 0.34
CASPA_HUMAN CASP10 Caspase-10 3.238e-10 0.30
MMP8_RAT Mmp8 Neutrophil collagenase 4.323e-10 0.32
PLK2_HUMAN PLK2 Serine/threonine-protein kinase PLK2 5.199e-10 0.33
ST14_MOUSE St14 Suppressor of tumorigenicity 14 protein homolog 5.485e-10 0.29
GLNA_HUMAN GLUL Glutamine synthetase 5.888e-10 0.31
TAT_HV1H2 tat Protein Tat 6.491e-10 0.29
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 1.015e-09 0.36
CATD_HUMAN CTSD Cathepsin D 2.182e-09 0.34
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 2.85e-09 0.29
MRAY_STAAU mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase 2.851e-09 0.29
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 3.421e-09 0.30
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 4.789e-09 0.28
CTRA_BOVIN Chymotrypsinogen A 5.154e-09 0.31
ITAV_HUMAN ITGAV Integrin alpha-V 5.286e-09 0.40
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 5.44e-09 0.33
ECE1_RAT Ece1 Endothelin-converting enzyme 1 6.532e-09 0.29
CATL1_HUMAN CTSL Cathepsin L1 7.219e-09 0.38
NK3R_RAT Tacr3 Neuromedin-K receptor 8.769e-09 0.29
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 8.998e-09 0.48
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 9.725e-09 0.36
V2R_RAT Avpr2 Vasopressin V2 receptor 9.783e-09 0.35
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 1.423e-08 0.39
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.78e-08 0.28
MMP7_HUMAN MMP7 Matrilysin 1.997e-08 0.43
PLMN_RAT Plg Plasminogen 3.566e-08 0.37
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 4.336e-08 0.35
CMA1_HUMAN CMA1 Chymase 4.802e-08 0.33
MEN1_HUMAN MEN1 Menin 6.699e-08 0.52
CBPA1_HUMAN CPA1 Carboxypeptidase A1 2.387e-07 0.30
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2.585e-07 0.36
THER_BACTH npr Thermolysin 2.805e-07 0.32
MMP26_HUMAN MMP26 Matrix metalloproteinase-26 2.994e-07 0.28
NEP_RAT Mme Neprilysin 3.41e-07 0.37
HDAC3_HUMAN HDAC3 Histone deacetylase 3 3.972e-07 0.32
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 4.153e-07 0.31
OPRX_HUMAN OPRL1 Nociceptin receptor 4.179e-07 0.34
TRY1_HUMAN PRSS1 Trypsin-1 4.497e-07 0.38
THRB_BOVIN F2 Prothrombin 4.694e-07 0.36
BKRB1_RAT Bdkrb1 B1 bradykinin receptor 5.457e-07 0.35
V2R_HUMAN AVPR2 Vasopressin V2 receptor 5.46e-07 0.34
HDA11_HUMAN HDAC11 Histone deacetylase 11 5.613e-07 0.31
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 6.077e-07 0.28
PAPA1_CARPA Papain 7.653e-07 0.38
CATD_BOVIN CTSD Cathepsin D 7.924e-07 0.31
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 1.055e-06 0.37
FA10_BOVIN F10 Coagulation factor X 1.081e-06 0.36
UR2R_RAT Uts2r Urotensin-2 receptor 2.564e-06 0.39
Q82323_9DELA Protease 3.254e-06 0.29
DRD1_HUMAN DRD1 D(1A) dopamine receptor 3.862e-06 0.37
CASP5_HUMAN CASP5 Caspase-5 4.4e-06 0.30
R1AB_SARS rep Replicase polyprotein 1ab 4.582e-06 0.31
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 4.797e-06 0.31
HDAC2_HUMAN HDAC2 Histone deacetylase 2 5.493e-06 0.32
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 5.567e-06 0.28
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 5.717e-06 0.29
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 6.213e-06 0.29
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 7.222e-06 0.29
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 8.558e-06 0.28
NK2R_HUMAN TACR2 Substance-K receptor 8.585e-06 0.43
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 8.84e-06 0.38

Nateglinide

NEP_RABIT MME Neprilysin 5.043e-216 0.49
ITA4_HUMAN ITGA4 Integrin alpha-4 7.269e-196 0.53
ACE_HUMAN ACE Angiotensin-converting enzyme 1.673e-178 0.49
NEP_RAT Mme Neprilysin 2.349e-175 0.48
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 3.345e-170 0.49
ITB1_HUMAN ITGB1 Integrin beta-1 5.573e-166 0.53
NEP_HUMAN MME Neprilysin 8.785e-160 0.49
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 1.497e-155 0.52
ITB7_HUMAN ITGB7 Integrin beta-7 5.325e-153 0.42
CBPA1_HUMAN CPA1 Carboxypeptidase A1 9.738e-141 0.49
MMP9_RAT Mmp9 Matrix metalloproteinase-9 8.573e-125 0.38
CPNS1_PIG CAPNS1 Calpain small subunit 1 3.832e-120 0.41
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 5.063e-119 0.40
TIMP3_RAT Timp3 Metalloproteinase inhibitor 3 3.479e-118 0.38
Q72874_9HIV1 pol Pol polyprotein 6.517e-113 0.40
OPRM_RAT Oprm1 Mu-type opioid receptor 1.267e-109 0.45
ACE_RABIT ACE Angiotensin-converting enzyme 2.056e-103 0.48
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 3.17e-102 0.42
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 3.178e-98 0.48
ACE_RAT Ace Angiotensin-converting enzyme 2.108e-96 0.49
NEP_MOUSE Mme Neprilysin 3.922e-95 0.46
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 5.303e-95 0.44
BRCA1_HUMAN BRCA1 Breast cancer type 1 susceptibility protein 1.49e-94 0.38
FCER2_HUMAN FCER2 Low affinity immunoglobulin epsilon Fc receptor 2.054e-92 0.39
NEP_PIG MME Neprilysin 7.464e-89 0.48
OPRD_RAT Oprd1 Delta-type opioid receptor 1.831e-88 0.41
AMPN_PIG ANPEP Aminopeptidase N 1.966e-88 0.47
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 1.149e-87 0.41
THER_BACTH npr Thermolysin 6.724e-86 0.40
ACE_MOUSE Ace Angiotensin-converting enzyme 2.172e-83 0.47
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 4.56e-82 0.40
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 5.588e-82 0.37
BLA1_STEMA Metallo-beta-lactamase L1 type 3 2.285e-80 0.42
RENI_HUMAN REN Renin 2.227e-77 0.48
NPFF2_RAT Npffr2 Neuropeptide FF receptor 2 6.325e-77 0.33
CATB_HUMAN CTSB Cathepsin B 3.724e-75 0.45
OPRD_MOUSE Oprd1 Delta-type opioid receptor 8.489e-75 0.39
NK1R_RAT Tacr1 Substance-P receptor 4.51e-69 0.43
AMP1_PLAFQ M1 family aminopeptidase 3.301e-66 0.42
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 5.684e-66 0.39
AMPB_RAT Rnpep Aminopeptidase B 6.23e-66 0.43
AMPN_HUMAN ANPEP Aminopeptidase N 3.242e-65 0.44
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.438e-64 0.39
MMP8_RAT Mmp8 Neutrophil collagenase 6.429e-64 0.38
ITA5_HUMAN ITGA5 Integrin alpha-5 9.822e-63 0.37
PEPT1_DERPT DERP1 Peptidase 1 1.146e-62 0.38
OPRM_CAVPO OPRM1 Mu-type opioid receptor 6.755e-62 0.38
CATB_BOVIN CTSB Cathepsin B 9.781e-62 0.36
NK1R_CAVPO TACR1 Substance-P receptor 1.428e-61 0.38
CTRA_BOVIN Chymotrypsinogen A 2.204e-61 0.41
VM1B1_BOTAS Snake venom metalloproteinase BaP1 8.59e-61 0.39
MMP1_HUMAN MMP1 Interstitial collagenase 2.174e-60 0.41
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 2.714e-59 0.37
PAPA1_CARPA Papain 5.331e-59 0.39
RIR1_MOUSE Rrm1 Ribonucleoside-diphosphate reductase large subunit 5.902e-58 0.38
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 2.887e-57 0.36
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 6.373e-57 0.37
CYSP_TRYCR Cruzipain 3.696e-55 0.36
MMP3_HUMAN MMP3 Stromelysin-1 1.41e-54 0.41
PP2AA_BOVIN PPP2CA Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 2.781e-54 0.32
CBPA1_BOVIN CPA1 Carboxypeptidase A1 3.955e-54 0.47
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 4.57e-54 0.50
AMPL_HUMAN LAP3 Cytosol aminopeptidase 7.357e-54 0.43
MBOA4_HUMAN MBOAT4 Ghrelin O-acyltransferase 8.03e-54 0.30
Q95PM0_TRYBR rhodesain Cysteine protease 8.404e-54 0.43
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 1.164e-53 0.36
LKHA4_CAVPO LTA4H Leukotriene A-4 hydrolase 1.285e-53 0.33
AMPB_MOUSE Rnpep Aminopeptidase B 4.375e-53 0.42
AMPL_BOVIN LAP3 Cytosol aminopeptidase 4.375e-53 0.42
CATL1_HUMAN CTSL Cathepsin L1 4.577e-53 0.44
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 5.398e-53 0.41
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 8.009e-53 0.42
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 9.711e-53 0.39
EDNRA_MOUSE Ednra Endothelin-1 receptor 1.007e-52 0.34
CATB_RAT Ctsb Cathepsin B 1.338e-52 0.35
CMA1_HUMAN CMA1 Chymase 1.753e-52 0.41
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 2.472e-50 0.39
Q4U254_9ENTO protease Protease 1.165e-49 0.38
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 1.36e-49 0.39
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 1.36e-49 0.39
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 1.36e-49 0.39
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 1.36e-49 0.39
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 1.36e-49 0.39
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 1.36e-49 0.39
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 1.36e-49 0.39
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 1.36e-49 0.39
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 1.36e-49 0.39
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 1.36e-49 0.39
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 1.36e-49 0.39
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 1.36e-49 0.39
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 1.36e-49 0.39
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 1.36e-49 0.39
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 1.36e-49 0.39
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 1.36e-49 0.39
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 1.36e-49 0.39
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 1.36e-49 0.39
ECE1_RAT Ece1 Endothelin-converting enzyme 1 1.416e-48 0.47
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 1.55e-48 0.39
DPO3B_ECOLI dnaN Beta sliding clamp 4.627e-48 0.38
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 4.755e-48 0.39
CATL1_BOVIN CTSL Cathepsin L1 9.96e-48 0.39
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 3.845e-46 0.39
XPP2_RAT Xpnpep2 Xaa-Pro aminopeptidase 2 5.821e-46 0.35
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 8.278e-46 0.47
Q99P97_RAT Histone deacetylase 6 9.43e-46 0.36
PSB10_HUMAN PSMB10 Proteasome subunit beta type-10 4.879e-44 0.39
FA11_HUMAN F11 Coagulation factor XI 6.658e-44 0.46
Q6IE76_BOVIN FDFT1 FDFT1 protein 3.059e-43 0.34
FA7_RABIT F7 Coagulation factor VII 4.275e-43 0.34
KLKB1_HUMAN KLKB1 Plasma kallikrein 7.382e-43 0.47
CANX_CHICK Calpain-1 catalytic subunit 1.038e-42 0.34
Q9YQ12_9HIV1 protease Protease 1.238e-40 0.35
PSA1_HUMAN PSMA1 Proteasome subunit alpha type-1 1.603e-40 0.39
PSA2_HUMAN PSMA2 Proteasome subunit alpha type-2 1.603e-40 0.39
PSA3_HUMAN PSMA3 Proteasome subunit alpha type-3 1.603e-40 0.39
PSA4_HUMAN PSMA4 Proteasome subunit alpha type-4 1.603e-40 0.39
PSA5_HUMAN PSMA5 Proteasome subunit alpha type-5 1.603e-40 0.39
PSA6_HUMAN PSMA6 Proteasome subunit alpha type-6 1.603e-40 0.39
PSA7_HUMAN PSMA7 Proteasome subunit alpha type-7 1.603e-40 0.39
PSB11_HUMAN PSMB11 Proteasome subunit beta type-11 1.603e-40 0.39
PSB3_HUMAN PSMB3 Proteasome subunit beta type-3 1.603e-40 0.39
PSB4_HUMAN PSMB4 Proteasome subunit beta type-4 1.603e-40 0.39
PSB6_HUMAN PSMB6 Proteasome subunit beta type-6 1.603e-40 0.39
PSB7_HUMAN PSMB7 Proteasome subunit beta type-7 1.603e-40 0.39
PSMA8_HUMAN PSMA8 Proteasome subunit alpha-type 8 1.603e-40 0.39
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2.034e-40 0.33
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 3.483e-40 0.34
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 4.411e-40 0.35
Q9NAW4_PLAFA Cysteine protease falcipain-3 5.613e-40 0.32
TERA_HUMAN VCP Transitional endoplasmic reticulum ATPase 9.101e-40 0.36
POLG_HRV14 Genome polyprotein 5.459e-39 0.31
CATD_BOVIN CTSD Cathepsin D 1.248e-38 0.37
IL2RA_HUMAN IL2RA Interleukin-2 receptor subunit alpha 1.381e-38 0.31
MMP2_HUMAN MMP2 72 kDa type IV collagenase 1.877e-38 0.45
POL_HV1A2 gag-pol Gag-Pol polyprotein 5.682e-38 0.31
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 8.475e-38 0.32
PEPC_HUMAN PGC Gastricsin 1.475e-37 0.35
EDNRB_RAT Ednrb Endothelin receptor type B 2.274e-37 0.36
TRY1_BOVIN Cationic trypsin 2.675e-37 0.38
CATK_HUMAN CTSK Cathepsin K 3.782e-37 0.44
CBX7_HUMAN CBX7 Chromobox protein homolog 7 4.858e-37 0.32
ITAV_HUMAN ITGAV Integrin alpha-V 7.767e-37 0.41
NK3R_CAVPO TACR3 Neuromedin-K receptor 7.784e-37 0.36
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 3.14e-36 0.34
CBX5_HUMAN CBX5 Chromobox protein homolog 5 3.875e-36 0.29
PLMN_BOVIN PLG Plasminogen 4.458e-36 0.31
ECE1_BOVIN ECE1 Endothelin-converting enzyme 1 6.264e-36 0.30
G1FEK8_9CALI Protease 6.395e-36 0.28
I1U3K2_9CALI POL Nonstructural polyprotein 6.395e-36 0.28
TRHDE_HUMAN TRHDE Thyrotropin-releasing hormone-degrading ectoenzyme 1.215e-35 0.28
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 1.261e-35 0.34
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 1.407e-35 0.32
CATH_RAT Ctsh Pro-cathepsin H 3.088e-35 0.29
CATJ_RAT Ctsj Cathepsin J 3.088e-35 0.29
CTRB_BOVIN Chymotrypsinogen B 5.865e-35 0.30
OPRD_HUMAN OPRD1 Delta-type opioid receptor 5.944e-35 0.41
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 6.772e-35 0.40
OPRK_RAT Oprk1 Kappa-type opioid receptor 7.746e-35 0.35
CATL1_RAT Ctsl Cathepsin L1 8.7e-35 0.31
AMPB_HUMAN RNPEP Aminopeptidase B 3.269e-34 0.34
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 4.527e-34 0.33
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 6.114e-34 0.35
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 1.245e-33 0.38
NTR1_RAT Ntsr1 Neurotensin receptor type 1 2.021e-33 0.34
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 2.128e-33 0.35
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 2.197e-33 0.39
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 3.099e-33 0.43
ACACB_HUMAN ACACB Acetyl-CoA carboxylase 2 5.182e-33 0.45
CATD_HUMAN CTSD Cathepsin D 6.382e-33 0.41
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 1.02e-32 0.48
MMP8_HUMAN MMP8 Neutrophil collagenase 2.772e-32 0.40
KLK5_HUMAN KLK5 Kallikrein-5 5.495e-32 0.34
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 1.097e-31 0.34
MC4R_HUMAN MC4R Melanocortin receptor 4 2.626e-31 0.40
SSPA_STAAU sspA Glutamyl endopeptidase 3.323e-31 0.30
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 2.17e-30 0.34
XPP2_HUMAN XPNPEP2 Xaa-Pro aminopeptidase 2 4.176e-30 0.35
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 1.345e-29 0.32
CATC_RAT Ctsc Dipeptidyl peptidase 1 2.502e-29 0.29
XPP1_HUMAN XPNPEP1 Xaa-Pro aminopeptidase 1 2.672e-29 0.35
CBX8_HUMAN CBX8 Chromobox protein homolog 8 3.845e-29 0.31
CATG_HUMAN CTSG Cathepsin G 5.937e-29 0.39
CP125_MYCTU cyp125 Steroid C26-monooxygenase 1.52e-28 0.35
Q9NBD4_PLAFA Cysteine protease falcipain-2 2.984e-28 0.35
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 9.873e-28 0.31
Q3HTL5_PLAFA fp2B Falcipain 2B 1.891e-27 0.34
ANF_HUMAN NPPA Natriuretic peptides A 2.761e-27 0.45
NK2R_MESAU TACR2 Substance-K receptor 5.119e-27 0.32
ITB3_HUMAN ITGB3 Integrin beta-3 9.329e-27 0.39
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 2.649e-26 0.42
RENI_RAT Ren1 Renin 3.645e-26 0.31
THRB_HUMAN F2 Prothrombin 3.709e-26 0.38
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 5.132e-26 0.36
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 6.575e-26 0.37
MDM4_HUMAN MDM4 Protein Mdm4 1.912e-25 0.48
PEPD_HUMAN PEPD Xaa-Pro dipeptidase 2.768e-25 0.34
OPRM_HUMAN OPRM1 Mu-type opioid receptor 3.165e-25 0.39
OPRM_MOUSE Oprm1 Mu-type opioid receptor 5.804e-25 0.36
PLMN_HUMAN PLG Plasminogen 6.154e-25 0.44
GNPAT_HUMAN GNPAT Dihydroxyacetone phosphate acyltransferase 6.482e-25 0.40
CAN2_PIG CAPN2 Calpain-2 catalytic subunit 7.787e-25 0.38
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 8.215e-25 0.38
HDAC1_RAT Hdac1 Histone deacetylase 1 9.178e-25 0.32
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 2.309e-24 0.40
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 3.392e-24 0.37
HPGDS_MOUSE Hpgds Hematopoietic prostaglandin D synthase 3.794e-24 0.30
MMP7_HUMAN MMP7 Matrilysin 4.55e-24 0.39
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 7.008e-24 0.45
PEPA_PIG PGA Pepsin A 1.131e-23 0.37
CATZ_RAT Ctsz Cathepsin Z 1.348e-23 0.29
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 1.385e-23 0.34
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 1.517e-23 0.37
CAN1_RAT Capn1 Calpain-1 catalytic subunit 1.64e-23 0.32
CATS_HUMAN CTSS Cathepsin S 1.876e-23 0.44
CARP_YEAST PEP4 Saccharopepsin 2.117e-23 0.29
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 3.259e-23 0.37
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 4.246e-23 0.38
CATE_HUMAN CTSE Cathepsin E 4.607e-23 0.35
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 6.108e-23 0.31
KLK1_HUMAN KLK1 Kallikrein-1 7.549e-23 0.37
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 1.635e-22 0.39
QRFPR_HUMAN QRFPR Pyroglutamylated RF-amide peptide receptor 2.099e-22 0.31
SOAT1_CHLAE SOAT1 Sterol O-acyltransferase 1 3.758e-22 0.35
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 6.017e-22 0.38
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 6.238e-22 0.39
CTRC_HUMAN CTRC Chymotrypsin-C 7.492e-22 0.40
BACE1_HUMAN BACE1 Beta-secretase 1 1.237e-21 0.41
PEPA5_HUMAN PGA5 Pepsin A-5 1.367e-21 0.30
GP142_HUMAN GPR142 Probable G-protein coupled receptor 142 2.113e-21 0.32
RIR1_MYCTU nrdE Ribonucleoside-diphosphate reductase subunit alpha 3.374e-21 0.34
CCKAR_RAT Cckar Cholecystokinin receptor type A 3.4e-21 0.39
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 3.619e-21 0.36
NK2R_RAT Tacr2 Substance-K receptor 4.163e-21 0.32
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 5.4e-21 0.35
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 6.654e-21 0.33
O90781_9PLVG HIV-1 protease HIV-1 protease 7.854e-21 0.31
EDNRA_PIG EDNRA Endothelin-1 receptor 1.524e-20 0.35
MYLK_CHICK Mylk Myosin light chain kinase, smooth muscle 2.186e-20 0.32
MENB_MYCTU menB 1,4-dihydroxy-2-naphthoyl-CoA synthase 3.806e-20 0.33
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 4.372e-20 0.31
NK1R_HUMAN TACR1 Substance-P receptor 7.02e-20 0.39
CBPB2_HUMAN CPB2 Carboxypeptidase B2 9.861e-20 0.39
Q82134_9DELA prt Protease 1.454e-19 0.33
EDNRB_PIG EDNRB Endothelin receptor type B 1.584e-19 0.36
TYRO_HUMAN TYR Tyrosinase 2.704e-19 0.37
ITA2_HUMAN ITGA2 Integrin alpha-2 4.631e-19 0.40
P88142_9HIV2 pol Pol polyprotein 6.559e-19 0.29
CATL2_HUMAN CTSV Cathepsin L2 6.582e-19 0.44
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 8.04e-19 0.34
CCR5_MACMU CCR5 C-C chemokine receptor type 5 9.803e-19 0.30
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 1.196e-18 0.31
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 1.463e-18 0.34
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 1.582e-18 0.35
COLA_CLOPE colA Collagenase ColA 1.91e-18 0.32
LY96_HUMAN LY96 Lymphocyte antigen 96 2.512e-18 0.35
CARP2_CANAX SAP2 Candidapepsin-2 2.636e-18 0.30
E2RFF5_CANLF ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 6.556e-18 0.28
O07911_STAAU agrC AgrC 7.964e-18 0.34
BODG_PSESK Gamma-butyrobetaine dioxygenase 9.478e-18 0.39
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 9.886e-18 0.33
FNTA_BOVIN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 1.652e-17 0.38
PEN2_HUMAN PSENEN Gamma-secretase subunit PEN-2 1.835e-17 0.37
PPM1B_HUMAN PPM1B Protein phosphatase 1B 2.642e-17 0.31
APH1A_HUMAN APH1A Gamma-secretase subunit APH-1A 3.694e-17 0.37
APH1B_HUMAN APH1B Gamma-secretase subunit APH-1B 3.694e-17 0.37
NICA_HUMAN NCSTN Nicastrin 3.694e-17 0.37
SOAT2_CHLAE SOAT2 Sterol O-acyltransferase 2 3.756e-17 0.35
PSN2_HUMAN PSEN2 Presenilin-2 3.934e-17 0.37
AMPX_VIBPR Bacterial leucyl aminopeptidase 5.404e-17 0.42
CATH_HUMAN CTSH Pro-cathepsin H 1.11e-16 0.33
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 1.11e-16 0.31
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.11e-16 0.39
DLG4_HUMAN DLG4 Disks large homolog 4 2.22e-16 0.31
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 2.22e-16 0.43
MC3R_HUMAN MC3R Melanocortin receptor 3 2.22e-16 0.36
NK2R_HUMAN TACR2 Substance-K receptor 2.22e-16 0.35
NK3R_HUMAN TACR3 Neuromedin-K receptor 2.22e-16 0.36
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 2.22e-16 0.34
PSN1_HUMAN PSEN1 Presenilin-1 2.22e-16 0.37
TRFR_MOUSE Trhr Thyrotropin-releasing hormone receptor 2.22e-16 0.39
BACE2_HUMAN BACE2 Beta-secretase 2 3.331e-16 0.41
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 4.441e-16 0.32
ITB8_HUMAN ITGB8 Integrin beta-8 5.551e-16 0.36
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 6.661e-16 0.39
Q9ERT1_MOUSE TRH-R2 Thyrotropin-releasing hormone receptor 2 7.772e-16 0.29
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 1.332e-15 0.32
EDNRA_HUMAN EDNRA Endothelin-1 receptor 1.887e-15 0.42
AMPN_MOUSE Anpep Aminopeptidase N 1.998e-15 0.42
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 1.998e-15 0.32
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 3.331e-15 0.34
TRY1_HUMAN PRSS1 Trypsin-1 5.551e-15 0.37
V1AR_RAT Avpr1a Vasopressin V1a receptor 5.551e-15 0.31
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 7.883e-15 0.44
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 9.548e-15 0.34
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 1.421e-14 0.32
CASP1_HUMAN CASP1 Caspase-1 1.843e-14 0.33
PLMN_RAT Plg Plasminogen 2.287e-14 0.34
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 2.465e-14 0.42
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 3.453e-14 0.37
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 3.73e-14 0.35
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 3.819e-14 0.37
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 5.396e-14 0.32
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 7.561e-14 0.28
CBPB_HELZE CPB Carboxypeptidase B 9.504e-14 0.30
BIRC2_HUMAN BIRC2 Baculoviral IAP repeat-containing protein 2 1.125e-13 0.39
GP142_MOUSE Gpr142 Probable G-protein coupled receptor 142 1.178e-13 0.30
FNTB_BOVIN FNTB Protein farnesyltransferase subunit beta 1.293e-13 0.38
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 1.372e-13 0.30
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 1.55e-13 0.32
A5A4K8_RABIT MLNR Motilin receptor 1.953e-13 0.32
ALBU_HUMAN ALB Serum albumin 2.001e-13 0.31
HDA11_HUMAN HDAC11 Histone deacetylase 11 2.065e-13 0.31
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 2.264e-13 0.35
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 4.3e-13 0.42
G3V673_RAT Adamts5 A disintegrin-like and metallopeptidase (Reprolysin type) with thrombospondin type 1 motif, 5 (Aggrecanase-2) 4.846e-13 0.28
TRFR_RAT Trhr Thyrotropin-releasing hormone receptor 5.848e-13 0.28
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 5.895e-13 0.31
CATF_HUMAN CTSF Cathepsin F 6.347e-13 0.32
ENTK_HUMAN TMPRSS15 Enteropeptidase 7.042e-13 0.32
PAR1_HUMAN F2R Proteinase-activated receptor 1 1.029e-12 0.34
FA10_BOVIN F10 Coagulation factor X 1.032e-12 0.37
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 1.163e-12 0.34
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 1.316e-12 0.32
PGTB1_BOVIN PGGT1B Geranylgeranyl transferase type-1 subunit beta 1.388e-12 0.34
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 1.572e-12 0.32
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 1.897e-12 0.36
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 1.987e-12 0.36
Q82323_9DELA Protease 2.234e-12 0.33
OPRX_HUMAN OPRL1 Nociceptin receptor 2.433e-12 0.39
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 3.444e-12 0.33
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 3.673e-12 0.36
B3DH72_DANRE oprd1b Opioid receptor, delta 1b 3.82e-12 0.30
O57585_DANRE oprd1a Opioid receptor homologue 3.82e-12 0.30
THRB_BOVIN F2 Prothrombin 3.998e-12 0.37
FNTA_HUMAN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 5.556e-12 0.36
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 6.114e-12 0.38
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 7.232e-12 0.35
SCYD_MAGO7 SDH1 Scytalone dehydratase 9.425e-12 0.35
PLM1_PLAFA Plasmepsin-1 1.036e-11 0.37
NAAA_HUMAN NAAA N-acylethanolamine-hydrolyzing acid amidase 1.045e-11 0.32
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 2.767e-11 0.34
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 4.757e-11 0.30
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 5.244e-11 0.39
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 5.527e-11 0.31
KIFC1_HUMAN KIFC1 Kinesin-like protein KIFC1 5.917e-11 0.30
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 8.493e-11 0.33
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 9.748e-11 0.39
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.332e-10 0.39
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.872e-10 0.43
CATC_HUMAN CTSC Dipeptidyl peptidase 1 2e-10 0.37
BKRB2_RABIT BDKRB2 B2 bradykinin receptor 2.789e-10 0.30
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 2.916e-10 0.34
GALR1_RAT Galr1 Galanin receptor type 1 3.022e-10 0.30
GALR2_RAT Galr2 Galanin receptor type 2 3.022e-10 0.30
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.695e-10 0.37
CCL2_HUMAN CCL2 C-C motif chemokine 2 3.761e-10 0.36
AMPL_PIG LAP3 Cytosol aminopeptidase 4.182e-10 0.29
CBPB1_HUMAN CPB1 Carboxypeptidase B 4.258e-10 0.39
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 4.685e-10 0.42
PTN2_HUMAN PTPN2 Tyrosine-protein phosphatase non-receptor type 2 4.69e-10 0.32
MC5R_HUMAN MC5R Melanocortin receptor 5 5.274e-10 0.32
GRIA1_HUMAN GRIA1 Glutamate receptor 1 5.494e-10 0.39
CARP_RHICH Rhizopuspepsin 5.529e-10 0.31
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 5.957e-10 0.34
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 6.569e-10 0.43
CHIA_SERMA chiA Chitinase A 7.541e-10 0.29
Q6DMN0_TOXGO CPL Cathepsin L 7.541e-10 0.29
PPCE_BOVIN PREP Prolyl endopeptidase 8.149e-10 0.31
MLX_HUMAN MLX Max-like protein X 1.012e-09 0.28
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 1.036e-09 0.41
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.087e-09 0.32
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 1.281e-09 0.32
ELAS_PSEAE lasB Elastase 1.914e-09 0.33
PRO_HTL1A gag-pro Gag-Pro polyprotein 2.077e-09 0.30
CASP3_HUMAN CASP3 Caspase-3 2.41e-09 0.33
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.604e-09 0.38
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 2.946e-09 0.29
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 3.009e-09 0.35
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 3.091e-09 0.35
GLNA_HUMAN GLUL Glutamine synthetase 3.22e-09 0.29
ROCK2_RAT Rock2 Rho-associated protein kinase 2 4.942e-09 0.36
MMP12_HUMAN MMP12 Macrophage metalloelastase 8.122e-09 0.33
PANK3_HUMAN PANK3 Pantothenate kinase 3 8.409e-09 0.35
IL2RA_MOUSE Il2ra Interleukin-2 receptor subunit alpha 1.229e-08 0.31
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 1.376e-08 0.38
NTR2_HUMAN NTSR2 Neurotensin receptor type 2 1.521e-08 0.29
CTRL_HUMAN CTRL Chymotrypsin-like protease CTRL-1 1.665e-08 0.28
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 1.718e-08 0.35
FA12_HUMAN F12 Coagulation factor XII 1.9e-08 0.34
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.926e-08 0.35
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 2.005e-08 0.42
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 2.53e-08 0.38
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 2.777e-08 0.32
PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 2.865e-08 0.33
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 3.46e-08 0.38
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 3.554e-08 0.38
SYMC_HUMAN MARS1 Methionine--tRNA ligase, cytoplasmic 4.573e-08 0.29
THB_RAT Thrb Thyroid hormone receptor beta 5.034e-08 0.35
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 5.363e-08 0.28
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 5.781e-08 0.32
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 6.537e-08 0.37
CYSK_MYCTU cysK1 O-acetylserine sulfhydrylase 6.815e-08 0.35
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 7.593e-08 0.34
FFAR2_MOUSE Ffar2 Free fatty acid receptor 2 8.176e-08 0.29
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 9.877e-08 0.32
A3EZI9_9HEPC NS3 Genome polyprotein 1.017e-07 0.35
NK2R_CAVPO TACR2 Substance-K receptor 1.042e-07 0.29
SPP2A_HUMAN SPPL2A Signal peptide peptidase-like 2A 1.106e-07 0.30
CASP1_MOUSE Casp1 Caspase-1 1.197e-07 0.33
Q9R297_RAT Mlnr Motilin receptor 1.452e-07 0.29
BLA2_BACCE blm Metallo-beta-lactamase type 2 1.98e-07 0.37
FNTB_RAT Fntb Protein farnesyltransferase subunit beta 2.151e-07 0.34
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 2.167e-07 0.38
TPA_HUMAN PLAT Tissue-type plasminogen activator 2.341e-07 0.37
FNTA_RAT Fnta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 2.444e-07 0.34
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 2.912e-07 0.32
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 3.083e-07 0.28
CASP8_HUMAN CASP8 Caspase-8 3.172e-07 0.33
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 3.335e-07 0.29
ALBU_BOVIN ALB Serum albumin 3.569e-07 0.32
PYRD_RAT Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 3.597e-07 0.33
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 3.723e-07 0.32
PPCE_PIG PREP Prolyl endopeptidase 4.452e-07 0.39
FDFT_RAT Fdft1 Squalene synthase 5.125e-07 0.40
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 5.581e-07 0.32
CASP7_HUMAN CASP7 Caspase-7 6.386e-07 0.33
PGH2_BOVIN PTGS2 Prostaglandin G/H synthase 2 6.416e-07 0.32
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 7.401e-07 0.33
FDFT_HUMAN FDFT1 Squalene synthase 7.61e-07 0.34
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 7.872e-07 0.30
MC3R_MOUSE Mc3r Melanocortin receptor 3 8.01e-07 0.29
PTPRB_HUMAN PTPRB Receptor-type tyrosine-protein phosphatase beta 1.153e-06 0.31
D2K2A8_9HEPC NS4A Non-structural protein 4A 1.154e-06 0.35
RIR1_HHV11 RIR1 Ribonucleoside-diphosphate reductase large subunit 1.176e-06 0.31
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 1.177e-06 0.30
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.292e-06 0.42
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 1.341e-06 0.32
BXA1_CLOBH botA Botulinum neurotoxin type A 1.414e-06 0.29
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 2.104e-06 0.28
POLG_HCV1 Genome polyprotein 2.349e-06 0.31
DPP2_HUMAN DPP7 Dipeptidyl peptidase 2 2.441e-06 0.32
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 2.488e-06 0.30
LUCI_AQULA Luciferin 4-monooxygenase 2.698e-06 0.31
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 2.709e-06 0.33
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 2.71e-06 0.38
OPRX_CAVPO OPRL1 Nociceptin receptor 2.849e-06 0.29
KLK7_HUMAN KLK7 Kallikrein-7 3.046e-06 0.33
NK3R_RAT Tacr3 Neuromedin-K receptor 3.825e-06 0.29
MC5R_MOUSE Mc5r Melanocortin receptor 5 3.876e-06 0.29
PLM2_PLAFA Plasmepsin-2 4.323e-06 0.37
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 4.367e-06 0.37
MC4R_MOUSE Mc4r Melanocortin receptor 4 4.489e-06 0.29
CATK_RABIT CTSK Cathepsin K 5.153e-06 0.31
ITB5_HUMAN ITGB5 Integrin beta-5 6.036e-06 0.36
TRY2_BOVIN Anionic trypsin 6.08e-06 0.37
DRD2_MOUSE Drd2 D(2) dopamine receptor 9.408e-06 0.33

Mycophenolate_mofetil

IMDH1_HUMAN IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 1.005e-209 0.70
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 2.067e-133 0.70
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 3.06e-27 0.33
IMDH_CRYNJ Inosine-5'-monophosphate dehydrogenase 9.359e-19 0.66
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 8.882e-15 0.32
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 6.526e-12 0.34
AOX_TRYBB AOX Alternative oxidase, mitochondrial 6.22e-10 0.31
ALBU_HUMAN ALB Serum albumin 9.396e-07 0.29
CNR1_RAT Cnr1 Cannabinoid receptor 1 6.623e-06 0.33

Warfarin

VKOR1_RAT Vkorc1 Vitamin K epoxide reductase complex subunit 1 9.619e-162 0.73
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 1.002e-113 0.63
NQO1_RAT Nqo1 NAD(P)H dehydrogenase [quinone] 1 3.847e-61 0.49
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 1.07e-49 0.32
CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 1.427e-29 0.29
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 1.79e-27 0.34
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 1.535e-24 0.30
PCSK7_HUMAN PCSK7 Proprotein convertase subtilisin/kexin type 7 7.259e-22 0.49
VKOR1_BOVIN VKORC1 Vitamin K epoxide reductase complex subunit 1 6.654e-21 0.33
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 2.498e-20 0.52
Q39829_SOYBN Lipoxygenase 4.879e-18 0.29
HST2_YEAST HST2 NAD-dependent protein deacetylase HST2 6.556e-18 0.28
P89582_9HIV2 pol Integrase 7.054e-18 0.40
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 2.22e-16 0.31
Q49PX0_9POXV N1L N1L 4.441e-16 0.31
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 8.882e-15 0.33
Q4U254_9ENTO protease Protease 5.218e-14 0.45
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 6.672e-14 0.30
BCAT1_HUMAN BCAT1 Branched-chain-amino-acid aminotransferase, cytosolic 1.797e-13 0.29
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 1.473e-12 0.42
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 4.416e-12 0.30
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 6.096e-12 0.32
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 9.7e-12 0.29
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 9.7e-12 0.29
Q72874_9HIV1 pol Pol polyprotein 1.372e-11 0.73
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 6.976e-11 0.29
KCNA3_MOUSE Kcna3 Potassium voltage-gated channel subfamily A member 3 1.025e-10 0.30
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 1.041e-10 0.30
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 1.105e-10 0.29
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 7.951e-10 0.34
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 1.686e-09 0.29
AOFB_RAT Maob Amine oxidase [flavin-containing] B 3.048e-09 0.35
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 3.957e-09 0.35
MOT4_HUMAN SLC16A3 Monocarboxylate transporter 4 4.226e-09 0.28
GPR55_HUMAN GPR55 G-protein coupled receptor 55 6.015e-09 0.34
STXA_SHIDY stxA Shiga toxin subunit A 2.572e-08 0.29
CALM1_HUMAN CALM1 Calmodulin-1 4.675e-08 0.28
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 2.414e-07 0.35
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 1.219e-06 0.30
GPR18_HUMAN GPR18 N-arachidonyl glycine receptor 2.123e-06 0.29
MDM4_HUMAN MDM4 Protein Mdm4 2.384e-06 0.29
B2LA1_HUMAN BCL2A1 Bcl-2-related protein A1 3.575e-06 0.29
NR1H4_MOUSE Nr1h4 Bile acid receptor 3.677e-06 0.29
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 5.091e-06 0.28
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 6.468e-06 0.34
Q7ZJM1_9HIV1 pol Integrase 9.161e-06 0.40

Mebendazole

RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 1.832e-143 0.73
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 1.727e-70 0.73
GRB7_HUMAN GRB7 Growth factor receptor-bound protein 7 2.782e-68 0.47
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 8.576e-68 0.43
KC1D_RAT Csnk1d Casein kinase I isoform delta 3.042e-67 0.43
Q9BJF5_TOXGO CDPK1 Calmodulin-domain protein kinase 1 5.997e-64 0.86
KC1A_BOVIN CSNK1A1 Casein kinase I isoform alpha 1.73e-57 0.42
ENL_HUMAN MLLT1 Protein ENL 2.478e-54 0.34
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 1.186e-48 0.40
GRM5_MOUSE Grm5 Metabotropic glutamate receptor 5 8.855e-47 0.47
C3SLB7_ECOLX glmU Bifunctional protein GlmU 6.853e-40 0.33
CYC_HUMAN CYCS Cytochrome c 7.528e-39 0.31
COX1_SHEEP MT-CO1 Cytochrome c oxidase subunit 1 4.265e-38 0.30
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 4.897e-30 0.43
GYRA_STAAU gyrA DNA gyrase subunit A 3.599e-29 0.46
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 4.494e-28 0.35
FTSZ_MYCTU ftsZ Cell division protein FtsZ 1.288e-26 0.33
LUCI_AQULA Luciferin 4-monooxygenase 1.111e-22 0.34
TIE2_HUMAN TEK Angiopoietin-1 receptor 2.568e-22 0.60
A5H660_SCHMA HDAC8 Histone deacetylase 8 7.915e-21 0.33
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 1.206e-20 0.71
HPSE_HUMAN HPSE Heparanase 1.647e-19 0.35
KCNN3_RAT Kcnn3 Small conductance calcium-activated potassium channel protein 3 4.321e-19 0.34
Q9FBC5_STREE fabK Enoyl-ACP reductase II 6.674e-19 0.32
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 3.646e-18 0.37
SHH_MOUSE Shh Sonic hedgehog protein 3.664e-18 0.36
GYRB_STAAU gyrB DNA gyrase subunit B 3.684e-18 0.46
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 2.903e-17 0.35
EST1_RABIT Liver carboxylesterase 1 1.11e-16 0.36
GLI1_HUMAN GLI1 Zinc finger protein GLI1 1.776e-15 0.29
GPAT1_MOUSE Gpam Glycerol-3-phosphate acyltransferase 1, mitochondrial 2.109e-15 0.29
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 2.998e-15 0.31
ISPD_ARATH ISPD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic 3.442e-15 0.29
PA_I000X PA Polymerase acidic protein 6.328e-15 0.28
KLK_PIG Glandular kallikrein 7.55e-15 0.31
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 8.993e-15 0.31
AA3R_HUMAN ADORA3 Adenosine receptor A3 1.554e-14 0.36
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 2.42e-14 0.53
KLF5_HUMAN KLF5 Krueppel-like factor 5 4.163e-14 0.49
PDE10_HUMAN PDE10A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 8.704e-14 0.36
VATB1_HUMAN ATP6V1B1 V-type proton ATPase subunit B, kidney isoform 3.084e-13 0.29
VPP1_CHICK ATP6V0A1 V-type proton ATPase 116 kDa subunit a isoform 1 3.084e-13 0.29
OGA_RAT Oga Protein O-GlcNAcase 3.164e-13 0.29
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 4.106e-13 0.32
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 5.156e-13 0.39
TESK2_HUMAN TESK2 Dual specificity testis-specific protein kinase 2 1.88e-12 0.30
THIO_HUMAN TXN Thioredoxin 2.91e-12 0.45
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 4.364e-12 0.86
REST_BORBU resT Telomere resolvase ResT 6.139e-12 0.29
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 7.253e-12 0.29
LUCI_RENRE Coelenterazine h 2-monooxygenase 9.498e-12 0.43
Q0GMK6_RABIT CDK4 Cyclin-dependent kinase 4 2.907e-11 0.30
LUCI_PHOPY Luciferin 4-monooxygenase 4.372e-11 0.55
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 4.439e-11 0.33
HPPD_HUMAN HPD 4-hydroxyphenylpyruvate dioxygenase 5.149e-11 0.30
GRM1_RAT Grm1 Metabotropic glutamate receptor 1 6.168e-11 0.31
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 1.105e-10 0.29
KPYK_STAAR pyk Pyruvate kinase 1.114e-10 0.41
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 1.354e-10 0.30
MEP50_HUMAN WDR77 Methylosome protein 50 1.522e-10 0.35
PLCB_HUMAN AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 1.596e-10 0.33
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 1.952e-10 0.35
O31272_9GAMM imiS Beta-lactamase 2.017e-10 0.33
PPBN_HUMAN ALPG Alkaline phosphatase, germ cell type 2.488e-10 0.39
PA_I34A1 PA Polymerase acidic protein 3.106e-10 0.30
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 7.139e-10 0.33
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 7.96e-10 0.33
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 8.4e-10 0.33
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 9.001e-10 0.31
PADI2_HUMAN PADI2 Protein-arginine deiminase type-2 1.012e-09 0.28
KC1E_HUMAN CSNK1E Casein kinase I isoform epsilon 1.306e-09 0.43
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 2.07e-09 0.34
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 3.346e-09 0.35
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 3.547e-09 0.33
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 3.798e-09 0.37
AAPK2_HUMAN PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 5.133e-09 0.30
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 7.102e-09 0.31
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 7.865e-09 0.86
MAP1_ECOLI map Methionine aminopeptidase 8.653e-09 0.43
SENP7_HUMAN SENP7 Sentrin-specific protease 7 2.216e-08 0.40
AAKG1_HUMAN PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 2.372e-08 0.30
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 2.399e-08 0.39
UREA_CANEN Urease 2.91e-08 0.30
PEBB_HUMAN CBFB Core-binding factor subunit beta 3.141e-08 0.30
UROK_HUMAN PLAU Urokinase-type plasminogen activator 5.511e-08 0.35
AA1R_HUMAN ADORA1 Adenosine receptor A1 6.166e-08 0.41
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 1.287e-07 0.32
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 1.462e-07 0.71
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 1.468e-07 0.38
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 1.785e-07 0.34
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 1.82e-07 0.30
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 2.645e-07 0.28
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 3.039e-07 0.86
STRP_STRP1 ska Streptokinase A 4.503e-07 0.48
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 4.778e-07 0.30
UCHL1_HUMAN UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1 5.533e-07 0.28
EST2_HUMAN CES2 Cocaine esterase 7.207e-07 0.36
FA7_HUMAN F7 Coagulation factor VII 7.566e-07 0.35
NORA_STAAU norA Quinolone resistance protein NorA 8.035e-07 0.35
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 8.94e-07 0.34
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 9.5e-07 0.33
D2K2A8_9HEPC NS4A Non-structural protein 4A 1.049e-06 0.30
CASP5_HUMAN CASP5 Caspase-5 1.239e-06 0.33
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 2.688e-06 0.38
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 3.568e-06 0.41
PLMN_HUMAN PLG Plasminogen 5.952e-06 0.33
TRYP_PIG Trypsin 6.097e-06 0.31
CASP4_HUMAN CASP4 Caspase-4 8.909e-06 0.33

Flumethasone

ATTY_RAT Tat Tyrosine aminotransferase 8.51e-129 0.49
GCR_RAT Nr3c1 Glucocorticoid receptor 2.011e-84 0.71
Q690N0_BOVIN PGR Progesterone receptor 6.372e-66 0.71
GCR_HUMAN NR3C1 Glucocorticoid receptor 6.248e-48 0.71
GCR_MOUSE Nr3c1 Glucocorticoid receptor 4.133e-12 0.36
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 2.209e-11 0.37
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.075e-10 0.34
GLNA_HUMAN GLUL Glutamine synthetase 1.075e-10 0.34
IL6_HUMAN IL6 Interleukin-6 1.495e-08 0.34
MMP1_HUMAN MMP1 Interstitial collagenase 8.054e-07 0.50
MCR_HUMAN NR3C2 Mineralocorticoid receptor 2.407e-06 0.71

Thiabendazole

PEBB_HUMAN CBFB Core-binding factor subunit beta 2.395e-118 0.47
MAP1_ECOLI map Methionine aminopeptidase 1.523e-55 0.66
TSSK3_HUMAN TSSK3 Testis-specific serine/threonine-protein kinase 3 3.6e-48 0.30
VGFR2_MOUSE Kdr Vascular endothelial growth factor receptor 2 1.803e-34 0.47
GRM5_MOUSE Grm5 Metabotropic glutamate receptor 5 7.049e-30 0.29
KCNN3_RAT Kcnn3 Small conductance calcium-activated potassium channel protein 3 5.932e-29 0.37
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 4.536e-27 0.37
UPAR_HUMAN PLAUR Urokinase plasminogen activator surface receptor 5.415e-25 0.38
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 1.37e-24 0.34
CCND3_HUMAN CCND3 G1/S-specific cyclin-D3 2.488e-21 0.38
SYFA_HAEIN pheS Phenylalanine--tRNA ligase alpha subunit 2.322e-19 0.31
SYFA_STRPN pheS Phenylalanine--tRNA ligase alpha subunit 2.322e-19 0.31
THIO_HUMAN TXN Thioredoxin 1.59e-18 0.35
HPSE_HUMAN HPSE Heparanase 1.11e-16 0.40
SHH_MOUSE Shh Sonic hedgehog protein 6.328e-15 0.33
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 1.077e-14 0.47
HSP12_CAEEL hsp-16.2 Heat shock protein Hsp-16.2 2.528e-13 0.40
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 4.541e-13 0.38
LUCI_PHOPY Luciferin 4-monooxygenase 1.81e-12 0.58
ALKB3_HUMAN ALKBH3 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 1.28e-11 0.31
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 6.437e-11 0.40
CCNA2_HUMAN CCNA2 Cyclin-A2 6.841e-11 0.38
GYRA_STAAU gyrA DNA gyrase subunit A 1.821e-10 0.36
KCNN3_HUMAN KCNN3 Small conductance calcium-activated potassium channel protein 3 3.144e-10 0.28
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 9.576e-10 0.47
CYSP_TRYCR Cruzipain 3.607e-09 0.32
KCNN1_HUMAN KCNN1 Small conductance calcium-activated potassium channel protein 1 5.048e-09 0.28
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 3.018e-08 0.47
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 3.106e-08 0.30
KCNN2_HUMAN KCNN2 Small conductance calcium-activated potassium channel protein 2 1.365e-07 0.28
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 3.235e-07 0.33
NRAM2_HUMAN SLC11A2 Natural resistance-associated macrophage protein 2 4.637e-07 0.29
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 9.875e-07 0.33
GYRB_STAAU gyrB DNA gyrase subunit B 1.632e-06 0.36
GYRB_MYCTU gyrB DNA gyrase subunit B 2.064e-06 0.30
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 2.346e-06 0.30
LDLR_HUMAN LDLR Low-density lipoprotein receptor 3.477e-06 0.28
KDM4B_HUMAN KDM4B Lysine-specific demethylase 4B 4.787e-06 0.31
GYRA_MYCTU gyrA DNA gyrase subunit A 5.03e-06 0.30

Trazodone

5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.097e-117 0.57
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.079e-101 0.52
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 3.227e-90 0.71
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.196e-64 0.45
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 9.472e-63 0.54
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.491e-59 0.46
DRD4_HUMAN DRD4 D(4) dopamine receptor 6.222e-50 0.46
DRD4_RAT Drd4 D(4) dopamine receptor 4.827e-48 0.37
DRD2_RAT Drd2 D(2) dopamine receptor 6.675e-48 0.57
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 6.427e-41 0.50
IGF1R_RAT Igf1r Insulin-like growth factor 1 receptor 1.377e-35 0.28
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 8.638e-34 0.48
DRD1_PIG DRD1 D(1A) dopamine receptor 2.245e-28 0.40
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 3.847e-27 0.32
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.157e-26 0.40
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 8.936e-26 0.48
DRD5_HUMAN DRD5 D(1B) dopamine receptor 1.766e-25 0.39
DRD3_RAT Drd3 D(3) dopamine receptor 3.357e-25 0.38
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.977e-24 0.45
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 3.679e-24 0.40
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.296e-23 0.41
DRD1_BOVIN DRD1 D(1A) dopamine receptor 4.737e-23 0.40
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 5.205e-23 0.46
B2LA1_MOUSE Bcl2a1 Bcl-2-related protein A1 8.776e-23 0.34
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.131e-21 0.54
B2LA1_HUMAN BCL2A1 Bcl-2-related protein A1 4.556e-21 0.34
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 2.148e-20 0.50
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 2.994e-20 0.44
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 1.499e-19 0.36
SL9A3_RAT Slc9a3 Sodium/hydrogen exchanger 3 3.403e-19 0.35
DRD2_BOVIN DRD2 D(2) dopamine receptor 3.759e-18 0.32
ADA1B_MOUSE Adra1b Alpha-1B adrenergic receptor 1.11e-16 0.32
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 1.11e-16 0.34
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 2.22e-16 0.36
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.665e-15 0.37
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 2.998e-15 0.30
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 2.809e-14 0.34
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 3.331e-14 0.44
HRH1_HUMAN HRH1 Histamine H1 receptor 6.251e-14 0.42
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 8.404e-14 0.41
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.519e-13 0.47
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.127e-11 0.52
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 1.86e-11 0.31
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 3.269e-11 0.37
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 4.24e-11 0.54
DRD1_RAT Drd1 D(1A) dopamine receptor 1.736e-10 0.45
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 2.323e-10 0.54
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 3.727e-10 0.57
REV1_HUMAN REV1 DNA repair protein REV1 4.306e-10 0.38
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 9.768e-10 0.32
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 6.365e-09 0.30
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 1.303e-08 0.36
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 3.504e-08 0.37
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 4.412e-08 0.33
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 4.961e-08 0.38
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 2.239e-07 0.36
PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 1.323e-06 0.29
ACHB4_RAT Chrnb4 Neuronal acetylcholine receptor subunit beta-4 2.966e-06 0.34
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 6.867e-06 0.31
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 8.185e-06 0.34
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 9.038e-06 0.42

Nedocromil

Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 5.73e-114 0.35
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 1.817e-64 0.32
GPR35_HUMAN GPR35 G-protein coupled receptor 35 2.732e-47 0.39
AL1A3_HUMAN ALDH1A3 Aldehyde dehydrogenase family 1 member A3 6.135e-11 0.29
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 4.398e-10 0.29
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 2.184e-09 0.29

Fludrocortisone

ATTY_RAT Tat Tyrosine aminotransferase 2.048e-108 0.41
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 3.195e-95 0.76
Q690N0_BOVIN PGR Progesterone receptor 6.348e-75 0.57
GCR_RAT Nr3c1 Glucocorticoid receptor 3.87e-59 0.51
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.571e-48 0.59
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 9.266e-46 0.38
GCR_HUMAN NR3C1 Glucocorticoid receptor 6.062e-43 0.78
GCR_MOUSE Nr3c1 Glucocorticoid receptor 3.086e-42 0.59
CP19A_HUMAN CYP19A1 Aromatase 9.291e-32 0.40
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 4.641e-30 0.38
PRGR_RAT Pgr Progesterone receptor 9.12e-28 0.32
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.445e-25 0.38
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 6.995e-25 0.49
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 3.691e-19 0.30
ANDR_RAT Ar Androgen receptor 2.22e-16 0.57
GLNA_HUMAN GLUL Glutamine synthetase 3.109e-15 0.49
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.309e-14 0.38
PRGR_RABIT PGR Progesterone receptor 6.32e-13 0.33
IL6_HUMAN IL6 Interleukin-6 3.987e-12 0.49
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 5.497e-12 0.34
MCR_HUMAN NR3C2 Mineralocorticoid receptor 5.257e-11 0.59
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 9.685e-11 0.33
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.366e-10 0.38
ERG2_YEAST ERG2 C-8 sterol isomerase 4.944e-09 0.36
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 5.867e-09 0.31
ANDR_MOUSE Ar Androgen receptor 1.635e-08 0.36
MCR_RAT Nr3c2 Mineralocorticoid receptor 5.551e-06 0.36
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 6.119e-06 0.35

Fluorescein

TYSY_CRYNB TMP1 Thymidylate synthase 3.657e-106 0.40
TYSY_ECOLI thyA Thymidylate synthase 1.812e-69 0.62
SECA1_STAA8 secA1 Protein translocase subunit SecA 1 1.405e-37 0.31
TYSY_LACCA thyA Thymidylate synthase 1.319e-32 0.62
TYSY_ENTFA thyA Thymidylate synthase 7.972e-32 0.62
C3SWJ7_ECOLX thyA Thymidylate synthase 2.773e-25 0.40
LYSC1_RAT Lyz1 Lysozyme C-1 2.847e-23 0.29
BGLR_RAT Gusb Beta-glucuronidase 4.879e-18 0.29
ITPR3_HUMAN ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 6.994e-15 0.44
1433G_HUMAN YWHAG 14-3-3 protein gamma 3.547e-10 0.37
ESR1_RAT Esr1 Estrogen receptor 1.678e-09 0.31
CALM1_HUMAN CALM1 Calmodulin-1 8.147e-09 0.31
O40947_HHV8 ORF 73 2.492e-08 0.61
ESR2_RAT Esr2 Estrogen receptor beta 3.793e-07 0.31
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 1.133e-06 0.31
CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 2.342e-06 0.38
WEE1_HUMAN WEE1 Wee1-like protein kinase 2.482e-06 0.34
TYRO_HUMAN TYR Tyrosinase 2.675e-06 0.30
LEG1_HUMAN LGALS1 Galectin-1 6.365e-06 0.32

Cephaloglycin

S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 5.695e-101 0.66
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 3.323e-62 0.66
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 8.618e-59 0.66
CATL1_RAT Ctsl Cathepsin L1 3.664e-56 0.38
B2ZTR6_ACIBA Beta-lactamase 1.241e-55 0.53
D6NSM8_ACIBA ampC Beta-lactamase 1.241e-55 0.53
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 1.834e-51 0.65
Q59401_ENTCL Beta-lactamase 8.227e-35 0.38
A2RP81_CITFR blaPER-2 Beta-lactamase 5.474e-32 0.38
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.147e-30 0.65
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 9.23e-26 0.50
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 2.077e-21 0.31
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 1.784e-20 0.37
MA2B1_HUMAN MAN2B1 Lysosomal alpha-mannosidase 1.006e-17 0.28
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 5.218e-15 0.52
AMPC_ENTCL ampC Beta-lactamase 3.086e-14 0.45
ELNE_HUMAN ELANE Neutrophil elastase 1.101e-12 0.46
Q6W9J1_ENTCL blaTEM-1 Beta-lactamase 7.705e-12 0.29
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 2.375e-11 0.31
CATB_RAT Ctsb Cathepsin B 2.67e-10 0.30
STRP_STRP1 ska Streptokinase A 3.224e-10 0.68
BLAC_STAAU blaZ Beta-lactamase 5.414e-09 0.32
BLAT_ECOLX bla; blaT-3; blaT-4; blaT-5; blaT-6 Beta-lactamase TEM 1.02e-08 0.38
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.255e-08 0.39
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1.258e-08 0.34
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 3.897e-08 0.68
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 1.025e-07 0.31
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 2.38e-07 0.30
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 2.488e-06 0.30

Ergotamine

CXCR3_MOUSE Cxcr3 C-X-C chemokine receptor type 3 1.237e-92 0.44
CXCR3_RAT Cxcr3 C-X-C chemokine receptor type 3 3.999e-79 0.41
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 3.373e-25 0.47
DRD1_MOUSE Drd1 D(1A) dopamine receptor 2.856e-23 0.45
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 2.22e-16 0.72
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.255e-14 0.72
AGRA_STAAU agrA Accessory gene regulator protein A 6.173e-14 0.34
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 3.21e-13 0.31
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 2.346e-12 0.45
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.667e-11 0.72
DRD1_HUMAN DRD1 D(1A) dopamine receptor 4.002e-11 0.72
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 4.783e-11 0.71
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 2.208e-10 0.48
EDNRA_PIG EDNRA Endothelin-1 receptor 8.019e-10 0.29
AT2A1_HUMAN ATP2A1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 1.022e-09 0.28
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 2.819e-09 0.51
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 7.826e-09 0.72
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 1.049e-08 0.31
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 1.083e-08 0.48
OXYR_RAT Oxtr Oxytocin receptor 1.883e-08 0.30
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 4.485e-08 0.72
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 1.435e-07 0.31
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.891e-07 0.72
MC4R_MOUSE Mc4r Melanocortin receptor 4 2.546e-07 0.31
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 2.6e-07 0.72
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 2.337e-06 0.59
HDAC1_RAT Hdac1 Histone deacetylase 1 3.132e-06 0.29
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 5.403e-06 0.59
V2R_RAT Avpr2 Vasopressin V2 receptor 7.242e-06 0.30

Trimethobenzamide

NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 4.53e-89 0.53
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 3.658e-83 0.37
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 6.512e-81 0.39
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 5.905e-73 0.35
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 1.342e-65 0.40
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 3.306e-59 0.33
Q0PJ46_PLAFA LDH Lactate dehydrogenase 9.728e-51 0.35
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 1.904e-49 0.32
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 2.948e-48 0.33
UR2R_HUMAN UTS2R Urotensin-2 receptor 9.203e-48 0.43
UR2R_MACMU UTS2R Urotensin-2 receptor 3.737e-47 0.38
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 9.981e-47 0.34
DPOL_HHV6U U38 DNA polymerase catalytic subunit 1.2e-44 0.41
MDHC_PIG MDH1 Malate dehydrogenase, cytoplasmic 5.799e-42 0.35
Q6VVP7_PLAFA Malate dehydrogenase 5.799e-42 0.35
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 1.914e-41 0.40
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 2.297e-41 0.44
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 4.446e-39 0.39
GLUT4_RAT Slc2a4 Solute carrier family 2, facilitated glucose transporter member 4 4.536e-38 0.30
GTR8_HUMAN SLC2A8 Solute carrier family 2, facilitated glucose transporter member 8 4.536e-38 0.30
FOXO1_HUMAN FOXO1 Forkhead box protein O1 6.694e-38 0.30
KIFC1_HUMAN KIFC1 Kinesin-like protein KIFC1 7.182e-38 0.32
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 1.296e-37 0.39
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 7.562e-37 0.37
PACR_RAT Adcyap1r1 Pituitary adenylate cyclase-activating polypeptide type I receptor 3.875e-36 0.29
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 1.769e-35 0.34
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 1.211e-34 0.45
HDAC1_MOUSE Hdac1 Histone deacetylase 1 1.919e-34 0.33
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 2.485e-34 0.33
TNR1A_HUMAN TNFRSF1A Tumor necrosis factor receptor superfamily member 1A 1.085e-33 0.39
ACES_RAT Ache Acetylcholinesterase 3.669e-32 0.35
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.692e-31 0.30
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 5.854e-30 0.36
EDNRB_MOUSE Ednrb Endothelin receptor type B 7.511e-30 0.31
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 2.431e-29 0.30
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 1.555e-28 0.43
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 3.279e-28 0.43
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 2.089e-26 0.32
SC5A7_HUMAN SLC5A7 High affinity choline transporter 1 2.156e-26 0.31
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 4.621e-26 0.32
KLKB1_HUMAN KLKB1 Plasma kallikrein 8.349e-26 0.33
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 4.38e-25 0.41
CAC1C_MOUSE Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 4.532e-25 0.31
Q49PX0_9POXV N1L N1L 5.579e-24 0.31
KDM6A_HUMAN KDM6A Lysine-specific demethylase 6A 6.243e-24 0.29
MPC2_HUMAN MPC2 Mitochondrial pyruvate carrier 2 2.847e-23 0.29
PRUN1_HUMAN PRUNE1 Exopolyphosphatase PRUNE1 2.847e-23 0.29
STABP_HUMAN STAMBP STAM-binding protein 5.056e-23 0.41
NAMPT_RAT Nampt Nicotinamide phosphoribosyltransferase 5.889e-23 0.28
LYOX_HUMAN LOX Protein-lysine 6-oxidase 9.597e-23 0.32
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 1.402e-22 0.34
ACES_HUMAN ACHE Acetylcholinesterase 2.169e-22 0.40
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 3.643e-22 0.42
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 4.01e-22 0.38
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 4.427e-22 0.34
UHRF1_HUMAN UHRF1 E3 ubiquitin-protein ligase UHRF1 8.154e-22 0.35
MDHM_PIG MDH2 Malate dehydrogenase, mitochondrial 8.739e-22 0.35
NR1H4_HUMAN NR1H4 Bile acid receptor 5.129e-21 0.50
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 5.578e-21 0.30
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 6.834e-21 0.46
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 7.095e-21 0.38
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 1.025e-20 0.29
RS27_HUMAN RPS27 40S ribosomal protein S27 1.694e-20 0.29
Q9FD53_STREE mvaD Diphosphomevalonate decarboxylase 1.745e-20 0.29
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 6.4e-20 0.42
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 7.494e-20 0.41
MMP13_HUMAN MMP13 Collagenase 3 2.052e-19 0.42
Q25270_LEIDO beta-tubulin Beta-tubulin 2.115e-19 0.34
PACR_HUMAN ADCYAP1R1 Pituitary adenylate cyclase-activating polypeptide type I receptor 3.129e-19 0.31
PDE6A_BOVIN PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 3.919e-19 0.30
ACES_ELEEL ache Acetylcholinesterase 4.79e-19 0.40
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 4.834e-19 0.32
THA_HUMAN THRA Thyroid hormone receptor alpha 5.069e-19 0.36
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 5.576e-19 0.30
Q9JKC1_RAT Bche Carboxylic ester hydrolase 6.347e-19 0.32
ACES_TETCF ache Acetylcholinesterase 9.798e-19 0.40
EDNRA_MOUSE Ednra Endothelin-1 receptor 1.046e-18 0.31
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 1.363e-18 0.37
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 2.52e-18 0.37
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 2.534e-18 0.33
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.56e-18 0.32
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 3.405e-18 0.33
LSS_HUMAN LSS Lanosterol synthase 4.479e-18 0.39
Q9XSW7_PIG Phosphodiesterase 4.879e-18 0.29
KLK1_HUMAN KLK1 Kallikrein-1 5.886e-18 0.33
HDAC1_HUMAN HDAC1 Histone deacetylase 1 5.931e-18 0.42
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 6.746e-18 0.38
CASR_HUMAN CASR Extracellular calcium-sensing receptor 7.714e-18 0.45
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.102e-17 0.36
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 3.546e-17 0.35
A5H660_SCHMA HDAC8 Histone deacetylase 8 4.457e-17 0.39
NORA_STAAU norA Quinolone resistance protein NorA 4.958e-17 0.38
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 1.11e-16 0.31
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 1.11e-16 0.40
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 2.22e-16 0.33
CHLE_HUMAN BCHE Cholinesterase 3.331e-16 0.40
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 3.331e-16 0.41
UBP47_HUMAN USP47 Ubiquitin carboxyl-terminal hydrolase 47 8.882e-16 0.32
THB_HUMAN THRB Thyroid hormone receptor beta 1.665e-15 0.36
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 2.665e-15 0.29
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 5.884e-15 0.28
HDAC6_HUMAN HDAC6 Histone deacetylase 6 7.438e-15 0.38
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 1.021e-14 0.35
ROCK2_RAT Rock2 Rho-associated protein kinase 2 1.166e-14 0.30
CAC1S_HUMAN CACNA1S Voltage-dependent L-type calcium channel subunit alpha-1S 1.588e-14 0.32
HDAC8_HUMAN HDAC8 Histone deacetylase 8 2.076e-14 0.38
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 2.409e-14 0.36
Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 1.218e-13 0.33
SCNNA_MOUSE Scnn1a Amiloride-sensitive sodium channel subunit alpha 4.028e-13 0.32
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 4.825e-13 0.31
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 6.33e-13 0.38
MEP1B_HUMAN MEP1B Meprin A subunit beta 9.815e-13 0.30
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 1.038e-12 0.41
HDAC2_HUMAN HDAC2 Histone deacetylase 2 1.057e-12 0.38
PDS_SYNE7 pds 15-cis-phytoene desaturase 1.365e-12 0.30
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 1.88e-12 0.30
SMO_HUMAN SMO Smoothened homolog 2.95e-12 0.35
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 3.211e-12 0.35
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 3.561e-12 0.32
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 6.026e-12 0.38
TLR1_MOUSE Tlr1 Toll-like receptor 1 8.273e-12 0.32
TLR2_MOUSE Tlr2 Toll-like receptor 2 8.273e-12 0.32
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 2.205e-11 0.32
HDAC7_HUMAN HDAC7 Histone deacetylase 7 3.627e-11 0.38
GPR4_MOUSE Gpr4 G-protein coupled receptor 4 6.433e-11 0.32
RFA1_HUMAN RPA1 Replication protein A 70 kDa DNA-binding subunit 7.38e-11 0.34
ESR1_HUMAN ESR1 Estrogen receptor 8.071e-11 0.38
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.075e-10 0.34
GPR4_RAT Gpr4 G-protein coupled receptor 4 3.683e-10 0.32
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 4.009e-10 0.41
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 5.315e-10 0.49
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 5.603e-10 0.42
HDAC9_HUMAN HDAC9 Histone deacetylase 9 6.393e-10 0.38
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 8.602e-10 0.38
HSF1_HUMAN HSF1 Heat shock factor protein 1 9.272e-10 0.31
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 1.034e-09 0.30
HDAC5_HUMAN HDAC5 Histone deacetylase 5 1.083e-09 0.38
MMP2_HUMAN MMP2 72 kDa type IV collagenase 1.163e-09 0.36
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.216e-09 0.35
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.315e-09 0.35
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 1.352e-09 0.31
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 1.742e-09 0.33
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 1.947e-09 0.30
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 2.11e-09 0.41
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 2.264e-09 0.34
FACE2_HUMAN RCE1 CAAX prenyl protease 2 2.685e-09 0.31
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 2.999e-09 0.39
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 3.862e-09 0.41
SCN3A_HUMAN SCN3A Sodium channel protein type 3 subunit alpha 7.889e-09 0.31
CLTR1_HUMAN CYSLTR1 Cysteinyl leukotriene receptor 1 8.427e-09 0.34
EGLN3_HUMAN EGLN3 Egl nine homolog 3 9.671e-09 0.33
HRH3_HUMAN HRH3 Histamine H3 receptor 1.249e-08 0.45
MDHM_HUMAN MDH2 Malate dehydrogenase, mitochondrial 1.317e-08 0.35
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 1.51e-08 0.32
SC5A2_MOUSE Slc5a2 Sodium/glucose cotransporter 2 2.016e-08 0.30
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 2.021e-08 0.31
GSK3B_MOUSE Gsk3b Glycogen synthase kinase-3 beta 2.184e-08 0.31
AURKA_HUMAN AURKA Aurora kinase A 2.322e-08 0.37
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 2.902e-08 0.38
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 3.012e-08 0.31
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 3.151e-08 0.35
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 3.392e-08 0.37
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 3.484e-08 0.38
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 3.6e-08 0.38
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 3.884e-08 0.34
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 4.18e-08 0.33
HDAC3_HUMAN HDAC3 Histone deacetylase 3 5.209e-08 0.38
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 6.351e-08 0.32
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 6.747e-08 0.32
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 7.216e-08 0.38
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 7.681e-08 0.33
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 8.47e-08 0.35
MIP_LEGPN mip Outer membrane protein MIP 9.381e-08 0.33
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 1.162e-07 0.28
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 1.204e-07 0.47
AOC3_HUMAN AOC3 Membrane primary amine oxidase 1.249e-07 0.35
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 1.305e-07 0.29
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.468e-07 0.29
CYSP_PLAFA Trophozoite cysteine proteinase 1.476e-07 0.31
FAK1_HUMAN PTK2 Focal adhesion kinase 1 1.618e-07 0.38
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 1.705e-07 0.30
UBP7_HUMAN USP7 Ubiquitin carboxyl-terminal hydrolase 7 1.746e-07 0.32
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 1.791e-07 0.43
PDE5A_HUMAN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 2.019e-07 0.36
Q76353_9HIV1 Integrase 2.065e-07 0.35
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 2.199e-07 0.34
Q7ZJM1_9HIV1 pol Integrase 2.233e-07 0.36
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 2.295e-07 0.38
OX2R_HUMAN HCRTR2 Orexin receptor type 2 2.382e-07 0.47
GYS1_HUMAN GYS1 Glycogen [starch] synthase, muscle 2.392e-07 0.34
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 2.498e-07 0.33
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 2.52e-07 0.46
PPARD_MOUSE Ppard Peroxisome proliferator-activated receptor delta 2.691e-07 0.35
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 2.808e-07 0.32
AMPN_PIG ANPEP Aminopeptidase N 2.945e-07 0.33
TRYP_PIG Trypsin 3.942e-07 0.31
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 4.098e-07 0.46
AURKB_HUMAN AURKB Aurora kinase B 4.33e-07 0.37
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 4.905e-07 0.29
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 5.189e-07 0.35
PRIO_SHEEP PRNP Major prion protein 5.506e-07 0.32
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 5.813e-07 0.30
PRKX_HUMAN PRKX cAMP-dependent protein kinase catalytic subunit PRKX 6.075e-07 0.36
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 7.434e-07 0.33
MMP3_HUMAN MMP3 Stromelysin-1 8.209e-07 0.38
O49150_SOLTU Lipoxygenase 9.875e-07 0.33
PLD1_RAT Pld1 Phospholipase D1 9.875e-07 0.33
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 1.056e-06 0.33
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.14e-06 0.29
RCE1_YEAST RCE1 CAAX prenyl protease 2 1.178e-06 0.31
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1.263e-06 0.32
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 1.347e-06 0.31
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 1.347e-06 0.29
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 1.359e-06 0.29
HDA11_HUMAN HDAC11 Histone deacetylase 11 1.385e-06 0.38
HRH3_CAVPO HRH3 Histamine H3 receptor 1.387e-06 0.35
DUS3_HUMAN DUSP3 Dual specificity protein phosphatase 3 1.48e-06 0.36
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 1.56e-06 0.32
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.574e-06 0.30
LYAM2_HUMAN SELE E-selectin 1.632e-06 0.32
CNR2_HUMAN CNR2 Cannabinoid receptor 2 1.966e-06 0.39
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 2.029e-06 0.28
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 2.211e-06 0.44
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 2.531e-06 0.35
DRD1_PIG DRD1 D(1A) dopamine receptor 2.864e-06 0.30
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 3.112e-06 0.37
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 3.135e-06 0.31
PDE4C_HUMAN PDE4C cAMP-specific 3',5'-cyclic phosphodiesterase 4C 3.385e-06 0.32
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 3.51e-06 0.43
LIPE_HUMAN LIPG Endothelial lipase 3.736e-06 0.45
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 3.933e-06 0.30
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 3.945e-06 0.40
PDE11_HUMAN PDE11A Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 4.409e-06 0.29
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 4.466e-06 0.33
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 4.993e-06 0.28
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 5.037e-06 0.28
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 5.238e-06 0.36
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 5.303e-06 0.30
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 6.871e-06 0.33
GLR_HUMAN GCGR Glucagon receptor 6.903e-06 0.33
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 7.076e-06 0.30
AGP1_YEAST AGP1 General amino acid permease AGP1 7.112e-06 0.29
LUCI_AQULA Luciferin 4-monooxygenase 7.112e-06 0.29
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 7.211e-06 0.44
CAH2_BOVIN CA2 Carbonic anhydrase 2 8.016e-06 0.32
PTN7_HUMAN PTPN7 Tyrosine-protein phosphatase non-receptor type 7 9.942e-06 0.35

Dyphylline

AA2AR_CAVPO ADORA2A Adenosine receptor A2a 9.69e-87 0.60
CNOT7_HUMAN CNOT7 CCR4-NOT transcription complex subunit 7 1.265e-75 0.47
CHIB1_ASPFM chiB1 Endochitinase B1 1.125e-68 0.41
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 2.125e-34 0.31
AA2AR_RAT Adora2a Adenosine receptor A2a 1.013e-28 0.59
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 2.761e-21 0.33
AA1R_RAT Adora1 Adenosine receptor A1 1.04e-20 0.59
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 9.054e-20 0.38
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 2.952e-19 0.45
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 4.275e-18 0.46
AA1R_CAVPO ADORA1 Adenosine receptor A1 6.439e-15 0.49
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 1.804e-13 0.38
KITH_HHV1 TK Thymidine kinase 3.627e-12 0.37
AA2BR_RAT Adora2b Adenosine receptor A2b 1.118e-09 0.59
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 1.99e-09 0.50
SAHH_RAT Ahcy Adenosylhomocysteinase 8.296e-09 0.42
NCOA3_HUMAN NCOA3 Nuclear receptor coactivator 3 1.446e-08 0.33
MOT1_HUMAN SLC16A1 Monocarboxylate transporter 1 6.721e-08 0.34
REV1_HUMAN REV1 DNA repair protein REV1 8.176e-08 0.29
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 8.205e-08 0.60
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 1.86e-07 0.31
CHIA_MOUSE Chia Acidic mammalian chitinase 2.544e-07 0.39
AA1R_BOVIN ADORA1 Adenosine receptor A1 8.666e-07 0.36
HPRT_HUMAN HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 1.866e-06 0.31
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 7.324e-06 0.31
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 8.55e-06 0.32
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 8.72e-06 0.44

Adefovir_dipivoxil

SAHH_HUMAN AHCY Adenosylhomocysteinase 2.079e-86 0.41
ADCY5_HUMAN ADCY5 Adenylate cyclase type 5 2.848e-76 0.44
OXGR1_RAT Oxgr1 2-oxoglutarate receptor 1 1.215e-74 0.33
ENPP1_RAT Enpp1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 3.121e-60 0.33
ASNS_HUMAN ASNS Asparagine synthetase [glutamine-hydrolyzing] 2.98e-57 0.31
SYQ_HUMAN QARS1 Glutamine--tRNA ligase 3.334e-57 0.33
KAD3_RAT Ak3 GTP:AMP phosphotransferase AK3, mitochondrial 6.78e-51 0.34
HPRT_HUMAN HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 3.054e-50 0.35
SAHH_RAT Ahcy Adenosylhomocysteinase 5.141e-49 0.40
DHE3_BOVIN GLUD1 Glutamate dehydrogenase 1, mitochondrial 1.08e-46 0.30
HSP7C_BOVIN HSPA8 Heat shock cognate 71 kDa protein 5.166e-42 0.33
WALK_STAAU walK Sensor protein kinase WalK 5.166e-42 0.33
P2RY4_RAT P2ry4 P2Y purinoceptor 4 3.024e-41 0.34
SAHH_MOUSE Ahcy Adenosylhomocysteinase 5.315e-41 0.30
MACD1_HUMAN MACROD1 ADP-ribose glycohydrolase MACROD1 6.045e-41 0.32
MACD2_HUMAN MACROD2 ADP-ribose glycohydrolase MACROD2 6.045e-41 0.32
XGPT_ECOLI gpt Xanthine phosphoribosyltransferase 1.972e-40 0.32
METK2_RAT Mat2a S-adenosylmethionine synthase isoform type-2 1.921e-39 0.31
ENPL_PIG HSP90B1 Endoplasmin 3.104e-39 0.31
KAD2_RAT Ak2 Adenylate kinase 2, mitochondrial 3.133e-39 0.34
SAHH_PLAF7 Adenosylhomocysteinase 7.309e-39 0.31
RN5A_HUMAN RNASEL 2-5A-dependent ribonuclease 1.317e-37 0.30
BT3A1_HUMAN BTN3A1 Butyrophilin subfamily 3 member A1 2.029e-37 0.38
KMT5C_HUMAN KMT5C Histone-lysine N-methyltransferase KMT5C 2.873e-37 0.29
SETB1_HUMAN SETDB1 Histone-lysine N-methyltransferase SETDB1 2.873e-37 0.29
DCAM_HUMAN AMD1 S-adenosylmethionine decarboxylase proenzyme 1.902e-36 0.30
IMDH2_MOUSE Impdh2 Inosine-5'-monophosphate dehydrogenase 2 3.345e-36 0.30
SETD2_HUMAN SETD2 Histone-lysine N-methyltransferase SETD2 3.875e-36 0.29
BIRA_ECOLI birA Bifunctional ligase/repressor BirA 5.94e-36 0.28
SYD_ECOLI aspS Aspartate--tRNA ligase 1.007e-35 0.28
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 4.283e-35 0.36
MTAP_MOUSE Mtap S-methyl-5'-thioadenosine phosphorylase 1.475e-34 0.30
ADA_BOVIN ADA Adenosine deaminase 5.634e-32 0.34
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 1.635e-31 0.34
PARG_BOVIN PARG Poly(ADP-ribose) glycohydrolase 3.648e-30 0.30
P2RY1_RAT P2ry1 P2Y purinoceptor 1 9.409e-30 0.34
P2Y11_HUMAN P2RY11 P2Y purinoceptor 11 5.579e-26 0.33
KTHY_HUMAN DTYMK Thymidylate kinase 7.67e-26 0.29
A0A0E7NXW5_STAAU birA Bifunctional ligase/repressor BirA 8.453e-26 0.30
ADA_MOUSE Ada Adenosine deaminase 4.386e-25 0.31
RN5A_MOUSE Rnasel 2-5A-dependent ribonuclease 3.317e-24 0.30
ANM7_HUMAN PRMT7 Protein arginine N-methyltransferase 7 8.089e-24 0.29
P2RX5_RAT P2rx5 P2X purinoceptor 5 1.222e-20 0.33
P2RX6_RAT P2rx6 P2X purinoceptor 6 1.222e-20 0.33
PANC_MYCTU panC Pantothenate synthetase 1.718e-20 0.34
BPL1_HUMAN HLCS Biotin--protein ligase 2.337e-20 0.28
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 1.335e-19 0.31
IUNH_CRIFA IUNH Inosine-uridine preferring nucleoside hydrolase 3.055e-19 0.37
O15727_TRYBB Inosine-adenosine-guanosine-nucleoside hydrolase 3.055e-19 0.37
METK1_RAT Mat1a S-adenosylmethionine synthase isoform type-1 6.741e-19 0.30
PARG_HUMAN PARG Poly(ADP-ribose) glycohydrolase 9.376e-19 0.30
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 9.835e-19 0.33
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 4.734e-18 0.30
KITH_RAT Tk1 Thymidine kinase, cytosolic 4.879e-18 0.29
SYI_ECOLI ileS Isoleucine--tRNA ligase 4.879e-18 0.29
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1.11e-16 0.35
MBTA_MYCTU mbtA Salicyl-AMP ligase / salicyl-S-ArCP synthetase 8.882e-16 0.30
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 2.665e-15 0.31
PNPH_HUMAN PNP Purine nucleoside phosphorylase 7.327e-15 0.32
G3P_HUMAN GAPDH Glyceraldehyde-3-phosphate dehydrogenase 2.34e-13 0.30
ADA_HUMAN ADA Adenosine deaminase 9.16e-13 0.30
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 2.186e-12 0.30
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 5.966e-12 0.29
PNPH_RAT Pnp Purine nucleoside phosphorylase 7.125e-12 0.30
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 7.484e-12 0.29
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 2.083e-11 0.31
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 3.215e-11 0.33
DPOLB_HUMAN POLB DNA polymerase beta 3.581e-11 0.38
ADH1A_HUMAN ADH1A Alcohol dehydrogenase 1A 4.877e-11 0.30
SYTC_HUMAN TARS1 Threonine--tRNA ligase 1, cytoplasmic 5.096e-11 0.29
SUV91_HUMAN SUV39H1 Histone-lysine N-methyltransferase SUV39H1 5.329e-11 0.29
IMDH1_HUMAN IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 7.407e-11 0.31
Q70E71_9ENTE aac(6')-Ii Aminoglycoside N(6')-acetyltransferase 1.647e-10 0.28
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 4.457e-10 0.34
AA3R_RAT Adora3 Adenosine receptor A3 7.063e-10 0.32
P2RX4_RAT P2rx4 P2X purinoceptor 4 8.646e-10 0.33
SYMC_HUMAN MARS1 Methionine--tRNA ligase, cytoplasmic 1.486e-09 0.37
BIP_HUMAN HSPA5 Endoplasmic reticulum chaperone BiP 1.881e-08 0.33
KMT2A_HUMAN KMT2A Histone-lysine N-methyltransferase 2A 2.316e-08 0.29
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 4.143e-08 0.30
I6YFP0_MYCTU birA Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase) 4.925e-08 0.32
AA1R_CHICK ADORA1 Adenosine receptor A1 6.225e-08 0.31
AA2AR_RAT Adora2a Adenosine receptor A2a 8.754e-08 0.37
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 8.995e-08 0.34
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 1.255e-07 0.30
5NTD_RAT Nt5e 5'-nucleotidase 4.266e-07 0.33
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 5.802e-07 0.34
5NTD_HUMAN NT5E 5'-nucleotidase 5.944e-07 0.33
EZH1_HUMAN EZH1 Histone-lysine N-methyltransferase EZH1 6.033e-07 0.29
INMT_HUMAN INMT Indolethylamine N-methyltransferase 6.033e-07 0.29
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 6.918e-07 0.34
DOT1L_HUMAN DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 7.536e-07 0.29
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 1.071e-06 0.28
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 1.184e-06 0.33
F16P1_RAT Fbp1 Fructose-1,6-bisphosphatase 1 1.331e-06 0.34
Q9Y0I0_9TRYP AT1 Adenosine transporter 1 1.815e-06 0.28
AA1R_RAT Adora1 Adenosine receptor A1 2.844e-06 0.33
ADCY5_RAT Adcy5 Adenylate cyclase type 5 3.203e-06 0.29
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 3.755e-06 0.31
ENPL_CANLF HSP90B1 Endoplasmin 4.243e-06 0.33
C3SIU2_ECOLX metJ Met repressor 6.605e-06 0.29
SYT_YERPE thrS Threonine--tRNA ligase 7.112e-06 0.29
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 7.355e-06 0.29

Chlorpropamide

TA2R_MOUSE Tbxa2r Thromboxane A2 receptor 3.257e-75 0.39
CCR9_HUMAN CCR9 C-C chemokine receptor type 9 1.236e-59 0.34
TA2R_RAT Tbxa2r Thromboxane A2 receptor 2.961e-51 0.43
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 3.352e-50 0.38
SYL_STAA8 leuS Leucine--tRNA ligase 1.389e-44 0.35
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 8.168e-43 0.46
NADE_BACAN nadE NH(3)-dependent NAD(+) synthetase 3.875e-36 0.29
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 3.145e-35 0.55
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 8.965e-34 0.38
MEP1B_HUMAN MEP1B Meprin A subunit beta 4.084e-31 0.42
THAS_HUMAN TBXAS1 Thromboxane-A synthase 5.901e-31 0.34
Q9TU16_CANLF PTGER4 Prostaglandin E receptor 4 8.023e-30 0.37
PFKA_TRYBB pfk ATP-dependent 6-phosphofructokinase 1.068e-29 0.34
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 5.227e-29 0.37
PSBA_SPIOL psbA Photosystem II protein D1 5.406e-29 0.38
SYL_ECOLI leuS Leucine--tRNA ligase 1.218e-28 0.35
MTNN_ECOLI mtnN 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1.375e-28 0.33
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 1.259e-27 0.36
PFKA_TRYCC pfk ATP-dependent 6-phosphofructokinase 4.804e-27 0.34
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.066e-25 0.63
CAH9_HUMAN CA9 Carbonic anhydrase 9 4.503e-25 0.63
CAH1_HUMAN CA1 Carbonic anhydrase 1 2.294e-24 0.63
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 7.893e-24 0.37
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.252e-23 0.63
MGAT1_HUMAN MGAT1 Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase 5.011e-23 0.30
CCR2_MOUSE Ccr2 C-C chemokine receptor type 2 4.501e-22 0.37
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 2.921e-21 0.32
MGAT2_MOUSE Mgat2 Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase 6.891e-21 0.30
APH1A_HUMAN APH1A Gamma-secretase subunit APH-1A 1.317e-20 0.40
APH1B_HUMAN APH1B Gamma-secretase subunit APH-1B 1.317e-20 0.40
NICA_HUMAN NCSTN Nicastrin 1.317e-20 0.40
PEN2_HUMAN PSENEN Gamma-secretase subunit PEN-2 1.342e-20 0.40
PSN2_HUMAN PSEN2 Presenilin-2 1.42e-20 0.40
PSN1_HUMAN PSEN1 Presenilin-1 8.042e-20 0.40
CAN1_RAT Capn1 Calpain-1 catalytic subunit 5.537e-19 0.37
S22A8_RAT Slc22a8 Solute carrier family 22 member 8 9.052e-19 0.30
COLA_CLOPE colA Collagenase ColA 2.551e-18 0.40
EPHB_MYCTO Epoxide hydrolase B 3.143e-18 0.29
CAH4_BOVIN CA4 Carbonic anhydrase 4 3.241e-17 0.47
GPAT1_MOUSE Gpam Glycerol-3-phosphate acyltransferase 1, mitochondrial 1.11e-16 0.32
MMP2_HUMAN MMP2 72 kDa type IV collagenase 1.11e-16 0.46
ABCBB_RAT Abcb11 Bile salt export pump 2.22e-16 0.41
CAH14_HUMAN CA14 Carbonic anhydrase 14 2.554e-15 0.46
PYGM_RAT Pygm Glycogen phosphorylase, muscle form 7.883e-15 0.28
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 1.643e-14 0.40
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 2.542e-14 0.35
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 2.753e-14 0.40
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 8.504e-14 0.40
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 1.174e-13 0.30
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.291e-13 0.37
PTGES_MOUSE Ptges Prostaglandin E synthase 2.482e-13 0.29
I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 2.89e-13 0.45
CXCR2_RABIT CXCR2 C-X-C chemokine receptor type 2 3.612e-13 0.32
TASP1_HUMAN TASP1 Threonine aspartase 1 4.12e-13 0.36
MMP8_HUMAN MMP8 Neutrophil collagenase 4.599e-13 0.40
PD2R2_MOUSE Ptgdr2 Prostaglandin D2 receptor 2 4.602e-13 0.31
PRP19_YEAST PRP19 Pre-mRNA-processing factor 19 6.108e-13 0.28
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 2.669e-12 0.40
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 4.156e-12 0.35
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 5.974e-12 0.33
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 6.597e-12 0.41
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 1.05e-11 0.37
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 1.279e-11 0.40
ABCC8_HUMAN ABCC8 ATP-binding cassette sub-family C member 8 1.28e-11 0.41
GSP_CRIFA GSP Glutathionylspermidine synthase 1.437e-11 0.28
F16P1_MOUSE Fbp1 Fructose-1,6-bisphosphatase 1 3.664e-11 0.32
COMT_PIG COMT Catechol O-methyltransferase 5.054e-11 0.35
MMP1_HUMAN MMP1 Interstitial collagenase 1.151e-10 0.41
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.209e-10 0.41
SYLC_HUMAN LARS1 Leucine--tRNA ligase, cytoplasmic 1.762e-10 0.35
MMP12_HUMAN MMP12 Macrophage metalloelastase 2.235e-10 0.40
LEF_BACAN lef Lethal factor 2.696e-10 0.41
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 3.105e-10 0.30
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 3.185e-10 0.41
Q6FTL6_CANGA NCE103 Carbonic anhydrase 5.539e-10 0.40
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 1.037e-09 0.34
PSBA_MARPO psbA Photosystem II protein D1 1.171e-09 0.30
CAN_CANAL NCE103 Carbonic anhydrase 1.207e-09 0.33
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.406e-09 0.29
LIMK2_HUMAN LIMK2 LIM domain kinase 2 2.559e-09 0.32
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 4.434e-09 0.47
MMP7_HUMAN MMP7 Matrilysin 4.613e-09 0.41
ILVB_YEAST ILV2 Acetolactate synthase catalytic subunit, mitochondrial 4.864e-09 0.28
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 1.35e-08 0.37
RORG_MOUSE Rorc Nuclear receptor ROR-gamma 1.636e-08 0.30
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 2.047e-08 0.33
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 2.786e-08 0.37
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 3.154e-08 0.45
TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 3.223e-08 0.35
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 3.232e-08 0.38
B2CL1_HUMAN BCL2L1 Bcl-2-like protein 1 5.502e-08 0.38
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 9.197e-08 0.43
CAH7_HUMAN CA7 Carbonic anhydrase 7 1.047e-07 0.38
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 1.2e-07 0.33
AL3A1_HUMAN ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 1.527e-07 0.30
MMP13_HUMAN MMP13 Collagenase 3 1.551e-07 0.41
METC_ECOLI metC Cystathionine beta-lyase MetC 1.631e-07 0.29
BCAT1_HUMAN BCAT1 Branched-chain-amino-acid aminotransferase, cytosolic 1.986e-07 0.30
MGAT3_HUMAN MGAT3 Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase 3.053e-07 0.30
POLG_DEN2P Genome polyprotein 3.96e-07 0.30
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 4.186e-07 0.40
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 5.079e-07 0.40
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 7.416e-07 0.38
EST1_RABIT Liver carboxylesterase 1 7.525e-07 0.31
AMYP_PIG AMY2 Pancreatic alpha-amylase 8.227e-07 0.29
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 1.034e-06 0.33
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 1.47e-06 0.33
Q8JXU8_9HEPC NS5B RNA-directed RNA polymerase 1.677e-06 0.43
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 1.923e-06 0.30
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 2.283e-06 0.36
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 2.61e-06 0.29
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 2.646e-06 0.50
MAP2_HUMAN METAP2 Methionine aminopeptidase 2 2.765e-06 0.37
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 3.045e-06 0.40
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 3.082e-06 0.50
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 4.296e-06 0.30
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 5.786e-06 0.29
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 5.786e-06 0.29
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 6.555e-06 0.37
KMO_RAT Kmo Kynurenine 3-monooxygenase 7.188e-06 0.33
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 9.587e-06 0.50

Homatropine_methylbromide

Q8WSF8_APLCA Soluble acetylcholine receptor 3.739e-75 0.52
Q8VH25_CAVPO GPM4 Muscarinic acetylcholine receptor 2.063e-61 0.49
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 8.588e-60 0.33
ACHP_LYMST Acetylcholine-binding protein 9.826e-47 0.52
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 1.028e-45 0.69
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 5.771e-45 0.69
ACER2_HUMAN ACER2 Alkaline ceramidase 2 3.875e-36 0.29
GSTT1_RAT Gstt1 Glutathione S-transferase theta-1 7.62e-36 0.28
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 4.897e-35 0.69
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 1.676e-28 0.69
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 2.172e-26 0.32
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 4.429e-26 0.69
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 6.617e-25 0.69
Q8VH27_CAVPO GPM2 Muscarinic acetylcholine receptor 2.034e-21 0.49
ACHA7_MOUSE Chrna7 Neuronal acetylcholine receptor subunit alpha-7 1.191e-20 0.49
TYRP1_MOUSE Tyrp1 5,6-dihydroxyindole-2-carboxylic acid oxidase 1.608e-19 0.31
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.272e-19 0.64
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 2.527e-18 0.76
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 7.199e-18 0.44
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 1.196e-17 0.33
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 8.882e-15 0.29
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.077e-14 0.38
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.665e-14 0.41
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.984e-13 0.64
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 2.411e-13 0.38
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 2.542e-13 0.49
AMYP_RAT Amy2 Pancreatic alpha-amylase 6.108e-13 0.28
Q8WMX0_BOVIN Muscarinic receptor M1 1.503e-12 0.44
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 7.838e-12 0.29
MRGX1_HUMAN MRGPRX1 Mas-related G-protein coupled receptor member X1 8.464e-12 0.32
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 9.501e-11 0.64
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 1.546e-09 0.49
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 2.645e-09 0.44
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 1.971e-08 0.35
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 1.427e-07 0.52
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 2.105e-07 0.29
AMPL_PIG LAP3 Cytosol aminopeptidase 1.978e-06 0.35

Oxacillin

GBRA5_HUMAN GABRA5 Gamma-aminobutyric acid receptor subunit alpha-5 1.017e-73 0.39
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 7.559e-63 0.79
Q3S5C3_SALNE sugE Efflux transporter 2.117e-48 0.79
Q48435_KLEPN bla LAT-2 Beta-lactamase 2.117e-48 0.79
BLAB_BACCE Metallo-beta-lactamase type 2 3.505e-34 0.39
COX2_HUMAN MT-CO2 Cytochrome c oxidase subunit 2 1.258e-31 0.32
NCAP_I33A0 NP Nucleoprotein 4.532e-25 0.31
A2RP81_CITFR blaPER-2 Beta-lactamase 1.325e-19 0.44
Q7T1G6_DANRE trpn1 Ion channel NompC 7.472e-14 0.46
AMPC_CITFR ampC Beta-lactamase 1.339e-11 0.28
BLAC_BACLI penP Beta-lactamase 1.339e-11 0.28
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 1.753e-10 0.33
GATA4_MOUSE Gata4 Transcription factor GATA-4 8.307e-10 0.41
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 8.307e-10 0.41
GRM7_RAT Grm7 Metabotropic glutamate receptor 7 4.409e-08 0.30
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 4.56e-08 0.37
FFAR2_MOUSE Ffar2 Free fatty acid receptor 2 8.502e-08 0.29
AMPC_ECOLI ampC Beta-lactamase 1.937e-07 0.41
STRP_STRP1 ska Streptokinase A 9.563e-07 0.79
CAH_METTE Carbonic anhydrase 5.02e-06 0.29

Procaine

CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 2.785e-73 0.46
AMYP_RAT Amy2 Pancreatic alpha-amylase 6.785e-65 0.47
Q8WMX0_BOVIN Muscarinic receptor M1 3.224e-34 0.47
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 4.216e-26 0.44
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 3.959e-25 0.56
KDM6A_HUMAN KDM6A Lysine-specific demethylase 6A 1.839e-23 0.29
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 1.769e-22 0.35
ERG2_YEAST ERG2 C-8 sterol isomerase 2.074e-22 0.44
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 6.346e-22 0.31
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.425e-20 0.34
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.485e-19 0.56
CAH2_BOVIN CA2 Carbonic anhydrase 2 1.021e-18 0.33
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 6.263e-18 0.71
S22A8_RAT Slc22a8 Solute carrier family 22 member 8 7.502e-18 0.28
ERG1_RAT Sqle Squalene monooxygenase 2.22e-16 0.33
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 5.995e-15 0.55
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 8.116e-14 0.30
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 5.338e-13 0.28
Q4Q5W4_LEIMA Putative squalene synthase 1.435e-11 0.34
DCOR_MOUSE Odc1 Ornithine decarboxylase 1.717e-11 0.31
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.209e-11 0.47
IKKB_MOUSE Ikbkb Inhibitor of nuclear factor kappa-B kinase subunit beta 3.134e-11 0.31
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 8.581e-11 0.29
B2LA1_MOUSE Bcl2a1 Bcl-2-related protein A1 1.233e-10 0.40
ENPP3_HUMAN ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 1.441e-10 0.33
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 1.5e-10 0.40
ACRO_HUMAN ACR Acrosin 2.588e-10 0.33
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 3.807e-10 0.35
A3KMY8_BOVIN GUSB Beta-glucuronidase 3.878e-10 0.33
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.177e-10 0.37
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 6.093e-10 0.46
PHOP1_HUMAN PHOSPHO1 Phosphoethanolamine/phosphocholine phosphatase 1.221e-09 0.53
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.251e-09 0.34
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 1.543e-09 0.30
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.744e-09 0.37
KAT2A_HUMAN KAT2A Histone acetyltransferase KAT2A 3.304e-09 0.31
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 6.111e-09 0.47
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 8.4e-09 0.40
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 1.58e-08 0.38
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 3.081e-08 0.41
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 3.386e-08 0.29
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 8.989e-08 0.47
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 1.264e-07 0.31
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 1.346e-07 0.30
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 2.206e-07 0.33
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 4.241e-07 0.36
GATA4_MOUSE Gata4 Transcription factor GATA-4 4.268e-07 0.29
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 4.268e-07 0.29
SCN3A_HUMAN SCN3A Sodium channel protein type 3 subunit alpha 6.315e-07 0.46
GBRB_MUSDO Rdl Gamma-aminobutyric acid receptor subunit beta 9.875e-07 0.33
PLEC_HUMAN PLEC Plectin 1.275e-06 0.38
ACRO_PIG ACR Acrosin 1.971e-06 0.33
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.395e-06 0.47
CAH14_HUMAN CA14 Carbonic anhydrase 14 2.759e-06 0.43
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 4.144e-06 0.66
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 7.896e-06 0.29
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 8.09e-06 0.28
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 8.855e-06 0.55

Sulfametopyrazine

CCR4_CANLF CCR4 C-C chemokine receptor type 4 1.69e-71 0.54
EDNRA_PIG EDNRA Endothelin-1 receptor 3.199e-55 0.36
BRD4_MOUSE Brd4 Bromodomain-containing protein 4 6.802e-50 0.32
BPTF_HUMAN BPTF Nucleosome-remodeling factor subunit BPTF 7.907e-48 0.32
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 4.644e-44 0.54
CCR9_HUMAN CCR9 C-C chemokine receptor type 9 5.279e-40 0.35
Q56D22_MACMU HSD11B1 Hydroxysteroid 11-beta dehydrogenase 1 3.875e-36 0.29
Q81VW8_BACAN folP Dihydropteroate synthase 3.324e-31 0.30
EDNRB_HUMAN EDNRB Endothelin receptor type B 3.54e-28 0.35
CYNT_HELPY cynT Carbonic anhydrase 5.285e-28 0.40
CCR4_MOUSE Ccr4 C-C chemokine receptor type 4 2.562e-27 0.54
SMCA4_HUMAN SMARCA4 Transcription activator BRG1 3.401e-27 0.32
Q5TU56_ANOGA 1272966 Carbonic anhydrase 2.564e-26 0.43
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 1.192e-23 0.49
SC5A7_RAT Slc5a7 High affinity choline transporter 1 2.847e-23 0.29
EDNRA_HUMAN EDNRA Endothelin-1 receptor 3.108e-22 0.36
EDNRA_RAT Ednra Endothelin-1 receptor 4.009e-21 0.49
BRD7_HUMAN BRD7 Bromodomain-containing protein 7 3.678e-19 0.32
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 4.299e-19 0.43
FFAR4_RAT Ffar4 Free fatty acid receptor 4 7.249e-19 0.36
C0IX24_STYPI CA2 Carbonic anhydrase 1.129e-18 0.40
KMO_RAT Kmo Kynurenine 3-monooxygenase 3.387e-18 0.35
Q5XX84_CANLF HSD11B1 11-beta-hydroxysteroid dehydrogenase type 1 4.879e-18 0.29
B2V8E3_SULSY Carbonate dehydratase 5.728e-18 0.40
B5SU02_STYPI CA Alpha carbonic anhydrase 5.728e-18 0.40
Q31FD6_HYDCU Carbonic anhydrase, alpha family 5.728e-18 0.40
A6YCJ1_9METZ Astrosclerin-3 4.976e-17 0.40
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 1.11e-16 0.40
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 2.554e-15 0.35
QCR7_HUMAN UQCRB Cytochrome b-c1 complex subunit 7 4.441e-15 0.29
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 4.885e-15 0.37
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 6.55e-15 0.32
CAN_YEAST NCE103 Carbonic anhydrase 6.883e-15 0.40
BRPF3_HUMAN BRPF3 Bromodomain and PHD finger-containing protein 3 2.243e-14 0.29
CAH13_MOUSE Ca13 Carbonic anhydrase 13 2.798e-14 0.43
S40A1_HUMAN SLC40A1 Solute carrier family 40 member 1 2.931e-14 0.35
CAH2_BOVIN CA2 Carbonic anhydrase 2 8.571e-14 0.34
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.283e-13 0.32
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 4.533e-13 0.42
CAH_METTE Carbonic anhydrase 5.089e-13 0.34
ABCBB_RAT Abcb11 Bile salt export pump 2.757e-12 0.30
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 6.39e-12 0.40
BAZ2B_HUMAN BAZ2B Bromodomain adjacent to zinc finger domain protein 2B 7.589e-12 0.32
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 2.942e-11 0.33
PGES2_HUMAN PTGES2 Prostaglandin E synthase 2 3.365e-11 0.37
Q6FTL6_CANGA NCE103 Carbonic anhydrase 2.251e-10 0.40
CAH15_MOUSE Ca15 Carbonic anhydrase 15 3.352e-10 0.34
Q388H8_TRYB2 Glycylpeptide N-tetradecanoyltransferase 6.655e-10 0.36
PI4KA_HUMAN PI4KA Phosphatidylinositol 4-kinase alpha 8.789e-10 0.32
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 2.942e-09 0.40
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 3.475e-09 0.36
BRD1_HUMAN BRD1 Bromodomain-containing protein 1 5.289e-09 0.30
IKBA_HUMAN NFKBIA NF-kappa-B inhibitor alpha 2.543e-08 0.29
METC_ECOLI metC Cystathionine beta-lyase MetC 6.665e-08 0.31
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 1.304e-07 0.34
CAN_CANAL NCE103 Carbonic anhydrase 1.641e-07 0.40
REV_HV1H2 rev Protein Rev 2.362e-07 0.29
SCN9A_HUMAN SCN9A Sodium channel protein type 9 subunit alpha 2.723e-07 0.42
CAH4_BOVIN CA4 Carbonic anhydrase 4 5.076e-07 0.43
KAT2B_HUMAN KAT2B Histone acetyltransferase KAT2B 5.48e-07 0.32
5NTD_HUMAN NT5E 5'-nucleotidase 5.944e-07 0.33
CAH6_HUMAN CA6 Carbonic anhydrase 6 5.982e-07 0.40
CAH9_HUMAN CA9 Carbonic anhydrase 9 7.317e-07 0.43
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.031e-06 0.43
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.042e-06 0.43
EDNRB_PIG EDNRB Endothelin receptor type B 2.135e-06 0.31
CAH12_HUMAN CA12 Carbonic anhydrase 12 4.752e-06 0.40
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 5.525e-06 0.40
BRD4_HUMAN BRD4 Bromodomain-containing protein 4 5.942e-06 0.35
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 7.099e-06 0.33
TIF1A_HUMAN TRIM24 Transcription intermediary factor 1-alpha 7.963e-06 0.31

Sulfacetamide

QCR7_HUMAN UQCRB Cytochrome b-c1 complex subunit 7 1.013e-60 0.32
SYL_STAA8 leuS Leucine--tRNA ligase 6.888e-48 0.38
CYNT_HELPY cynT Carbonic anhydrase 2.873e-43 0.45
Q5TU56_ANOGA 1272966 Carbonic anhydrase 1.252e-38 0.46
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 2.502e-38 0.46
CAH7_MOUSE Ca7 Carbonic anhydrase 7 5.351e-37 0.29
CAHX_FLABI Carbonic anhydrase 5.351e-37 0.29
B2V8E3_SULSY Carbonate dehydratase 1.043e-35 0.45
Q31FD6_HYDCU Carbonic anhydrase, alpha family 1.043e-35 0.45
CAH2_HUMAN CA2 Carbonic anhydrase 2 4.171e-35 0.59
CAH4_BOVIN CA4 Carbonic anhydrase 4 4.186e-35 0.59
A6YCJ1_9METZ Astrosclerin-3 8.146e-34 0.45
MEP1B_HUMAN MEP1B Meprin A subunit beta 8.571e-34 0.33
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 1.41e-33 0.45
C0IX24_STYPI CA2 Carbonic anhydrase 1.8e-33 0.45
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 2.878e-32 0.49
B5SU02_STYPI CA Alpha carbonic anhydrase 3.431e-32 0.45
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 2.562e-31 0.49
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 9.113e-31 0.45
CAH2_BOVIN CA2 Carbonic anhydrase 2 9.358e-31 0.45
SYL_ECOLI leuS Leucine--tRNA ligase 9.661e-31 0.38
CAH1_HUMAN CA1 Carbonic anhydrase 1 2.536e-30 0.54
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 1.341e-29 0.49
CAH14_HUMAN CA14 Carbonic anhydrase 14 3.323e-27 0.45
CAH_METTE Carbonic anhydrase 8.472e-27 0.45
CAH9_HUMAN CA9 Carbonic anhydrase 9 6.496e-26 0.54
Q6FTL6_CANGA NCE103 Carbonic anhydrase 1.284e-24 0.45
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.47e-24 0.54
CAH15_MOUSE Ca15 Carbonic anhydrase 15 2.812e-23 0.45
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 3.361e-23 0.42
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 3.117e-21 0.45
CAN_YEAST NCE103 Carbonic anhydrase 1.179e-20 0.42
CAH13_MOUSE Ca13 Carbonic anhydrase 13 1.635e-18 0.46
Q9HVB9_PSEAE Carbonic anhydrase 1.858e-18 0.29
Q5VLE3_EMEND rmtA RmtA 4.879e-18 0.29
I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 1.409e-17 0.42
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 3.075e-17 0.54
METC_ECOLI metC Cystathionine beta-lyase MetC 1.11e-16 0.39
SYTC_HUMAN TARS1 Threonine--tRNA ligase 1, cytoplasmic 2.22e-16 0.30
SYT_YERPE thrS Threonine--tRNA ligase 2.22e-16 0.30
MMP7_HUMAN MMP7 Matrilysin 4.441e-16 0.33
CAH7_HUMAN CA7 Carbonic anhydrase 7 9.992e-16 0.45
CAH6_HUMAN CA6 Carbonic anhydrase 6 1.554e-15 0.45
MYG_HUMAN MB Myoglobin 1.665e-15 0.29
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 2.331e-15 0.33
UT2_RAT Slc14a2 Urea transporter 2 2.887e-15 0.29
5NTD_HUMAN NT5E 5'-nucleotidase 4.552e-15 0.48
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 6.994e-15 0.32
CAH3_HUMAN CA3 Carbonic anhydrase 3 6.961e-14 0.45
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 7.55e-14 0.30
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 7.905e-14 0.44
CAN_CANAL NCE103 Carbonic anhydrase 2.753e-13 0.45
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 4.091e-13 0.38
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.142e-12 0.32
MMP2_HUMAN MMP2 72 kDa type IV collagenase 2.44e-12 0.49
VE1_HPV11 E1 Replication protein E1 4.044e-12 0.29
GSP_CRIFA GSP Glutathionylspermidine synthase 5.06e-12 0.29
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 1.082e-11 0.47
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.096e-11 0.45
O49150_SOLTU Lipoxygenase 1.333e-11 0.30
SYLC_HUMAN LARS1 Leucine--tRNA ligase, cytoplasmic 3.253e-11 0.38
MMP13_HUMAN MMP13 Collagenase 3 4.279e-11 0.49
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 5.194e-11 0.42
Q2PCB5_DICLA ca Carbonic anhydrase 6.343e-11 0.29
UT1_RAT Slc14a1 Urea transporter 1 8.191e-11 0.29
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 8.4e-11 0.32
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 8.581e-11 0.29
MMP1_HUMAN MMP1 Interstitial collagenase 1.11e-10 0.35
TASP1_HUMAN TASP1 Threonine aspartase 1 1.647e-10 0.28
MMP13_BOVIN MMP13 Collagenase 3 1.709e-10 0.31
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 3.107e-10 0.33
ENPP3_HUMAN ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 7.2e-10 0.31
O77078_PLAFA fabH Beta-ketoacyl-acyl carrier protein synthase III 6.138e-09 0.30
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 1.23e-08 0.33
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 1.566e-08 0.28
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.596e-08 0.33
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 6.857e-08 0.47
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 6.978e-08 0.29
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 1.477e-07 0.39
MMP26_HUMAN MMP26 Matrix metalloproteinase-26 1.792e-07 0.29
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 2.086e-07 0.45
LEF_BACAN lef Lethal factor 3.006e-07 0.33
MMP3_HUMAN MMP3 Stromelysin-1 3.198e-07 0.49
CAH11_HUMAN CA11 Carbonic anhydrase-related protein 11 3.447e-07 0.29
BKRB1_HUMAN BDKRB1 B1 bradykinin receptor 3.635e-07 0.34
CAH4_HUMAN CA4 Carbonic anhydrase 4 3.824e-07 0.45
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 4.177e-07 0.29
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 7.789e-07 0.30
MMP12_HUMAN MMP12 Macrophage metalloelastase 1.507e-06 0.35
COLA_CLOPE colA Collagenase ColA 1.782e-06 0.29
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 1.905e-06 0.37
NRAM_I77AB Neuraminidase 2.134e-06 0.31
CAH13_HUMAN CA13 Carbonic anhydrase 13 2.341e-06 0.45
MMP8_HUMAN MMP8 Neutrophil collagenase 4.013e-06 0.35
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 5.734e-06 0.29
CAN1_RAT Capn1 Calpain-1 catalytic subunit 7.112e-06 0.29
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 7.609e-06 0.45

Acamprosate

AL1A2_CHICK ALDH1A2 Retinal dehydrogenase 2 3.987e-46 0.37
PAO1_MAIZE MPAO1 Polyamine oxidase 1 7.156e-30 0.33
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 3.395e-18 0.34
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 8.639e-18 0.37
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 9.574e-18 0.34
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.11e-16 0.34
PRP19_YEAST PRP19 Pre-mRNA-processing factor 19 9.504e-14 0.30
BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 1.38e-13 0.42
AL1A3_HUMAN ALDH1A3 Aldehyde dehydrogenase family 1 member A3 1.753e-13 0.37
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 5.437e-13 0.37
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 4.794e-12 0.35
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 1.515e-11 0.37
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 1.635e-09 0.35
NEP_RAT Mme Neprilysin 2.38e-09 0.43
GRIA1_HUMAN GRIA1 Glutamate receptor 1 1.158e-06 0.28
GABR2_RAT Gabbr2 Gamma-aminobutyric acid type B receptor subunit 2 2.96e-06 0.41
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 4.647e-06 0.33

Rocuronium

IF4A1_MOUSE Eif4a1 Eukaryotic initiation factor 4A-I 3.55e-44 0.33
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 3.042e-18 0.30
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 4.884e-10 0.29
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 1.119e-09 0.58
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 3.262e-09 0.58
GBRD_HUMAN GABRD Gamma-aminobutyric acid receptor subunit delta 5.7e-08 0.30

Lamivudine

ISPE_ECOLI ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1.89e-41 0.33
DPOLB_HUMAN POLB DNA polymerase beta 2.168e-26 0.44
ADA_MOUSE Ada Adenosine deaminase 2.847e-23 0.29
KITH_VZVD TK Thymidine kinase 8.907e-19 0.29
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 1.286e-18 0.47
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 1.221e-15 0.43
O39930_9HEPC NS5b RNA-directed RNA polymerase 7.11e-13 0.38
V5TFZ2_9FLAV Nonstructural protein 5 1.067e-11 0.32
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 7.472e-09 0.48
CDD_MOUSE Cda Cytidine deaminase 4.905e-07 0.29
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 6.654e-07 0.34
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 1.025e-06 0.31
CDD_HUMAN CDA Cytidine deaminase 2.849e-06 0.29
ADCY5_RAT Adcy5 Adenylate cyclase type 5 5.567e-06 0.28
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 6.24e-06 0.62
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 7.566e-06 0.36

Atracurium_besylate

MMP26_HUMAN MMP26 Matrix metalloproteinase-26 5.642e-36 0.35
SCMU_MYCTU Secreted chorismate mutase 1.522e-35 0.28
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 3.896e-34 0.30
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 6.88e-34 0.35
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 3.292e-28 0.35
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.877e-25 0.31
CAC1C_MOUSE Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.481e-24 0.30
ACHB4_MOUSE Chrnb4 Neuronal acetylcholine receptor subunit beta-4 1.833e-20 0.36
ACHB2_MOUSE Chrnb2 Neuronal acetylcholine receptor subunit beta-2 3.881e-19 0.36
HCN2_MOUSE Hcn2 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 1.523e-18 0.29
EBPL_HUMAN EBPL Emopamil-binding protein-like 3.809e-18 0.29
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 7.772e-16 0.30
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 1.221e-15 0.35
ACPM_HUMAN NDUFAB1 Acyl carrier protein, mitochondrial 2.109e-15 0.29
CIA30_HUMAN NDUFAF1 Complex I intermediate-associated protein 30, mitochondrial 2.109e-15 0.29
NDUA1_HUMAN NDUFA1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 2.109e-15 0.29
NDUA2_HUMAN NDUFA2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 2.109e-15 0.29
NDUA3_HUMAN NDUFA3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 2.109e-15 0.29
NDUA5_HUMAN NDUFA5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 2.109e-15 0.29
NDUA6_HUMAN NDUFA6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 2.109e-15 0.29
NDUA7_HUMAN NDUFA7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 2.109e-15 0.29
NDUA8_HUMAN NDUFA8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 2.109e-15 0.29
NDUA9_HUMAN NDUFA9 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial 2.109e-15 0.29
NDUAA_HUMAN NDUFA10 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial 2.109e-15 0.29
NDUAB_HUMAN NDUFA11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 2.109e-15 0.29
NDUAC_HUMAN NDUFA12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 2.109e-15 0.29
NDUAD_HUMAN NDUFA13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 2.109e-15 0.29
NDUB1_HUMAN NDUFB1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 2.109e-15 0.29
NDUB2_HUMAN NDUFB2 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial 2.109e-15 0.29
NDUB3_HUMAN NDUFB3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 2.109e-15 0.29
NDUB4_HUMAN NDUFB4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 2.109e-15 0.29
NDUB5_HUMAN NDUFB5 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial 2.109e-15 0.29
NDUB6_HUMAN NDUFB6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 2.109e-15 0.29
NDUB7_HUMAN NDUFB7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 2.109e-15 0.29
NDUB8_HUMAN NDUFB8 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial 2.109e-15 0.29
NDUB9_HUMAN NDUFB9 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 2.109e-15 0.29
NDUBA_HUMAN NDUFB10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 2.109e-15 0.29
NDUBB_HUMAN NDUFB11 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial 2.109e-15 0.29
NDUC1_HUMAN NDUFC1 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial 2.109e-15 0.29
NDUC2_HUMAN NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2 2.109e-15 0.29
NDUF2_HUMAN NDUFAF2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 2.109e-15 0.29
NDUF3_HUMAN NDUFAF3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 2.109e-15 0.29
NDUF4_HUMAN NDUFAF4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 2.109e-15 0.29
NDUS1_HUMAN NDUFS1 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 2.109e-15 0.29
NDUS2_HUMAN NDUFS2 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 2.109e-15 0.29
NDUS3_HUMAN NDUFS3 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 2.109e-15 0.29
NDUS4_HUMAN NDUFS4 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 2.109e-15 0.29
NDUS5_HUMAN NDUFS5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 2.109e-15 0.29
NDUS6_HUMAN NDUFS6 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial 2.109e-15 0.29
NDUS7_HUMAN NDUFS7 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial 2.109e-15 0.29
NDUS8_HUMAN NDUFS8 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial 2.109e-15 0.29
NDUV1_HUMAN NDUFV1 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 2.109e-15 0.29
NDUV2_HUMAN NDUFV2 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 2.109e-15 0.29
NDUV3_HUMAN NDUFV3 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 2.109e-15 0.29
NU1M_HUMAN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 2.109e-15 0.29
NU2M_HUMAN MT-ND2 NADH-ubiquinone oxidoreductase chain 2 2.109e-15 0.29
NU3M_HUMAN MT-ND3 NADH-ubiquinone oxidoreductase chain 3 2.109e-15 0.29
NU4LM_HUMAN MT-ND4L NADH-ubiquinone oxidoreductase chain 4L 2.109e-15 0.29
NU5M_HUMAN MT-ND5 NADH-ubiquinone oxidoreductase chain 5 2.109e-15 0.29
NU6M_HUMAN MT-ND6 NADH-ubiquinone oxidoreductase chain 6 2.109e-15 0.29
NUA4L_HUMAN NDUFA4L2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 2.109e-15 0.29
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 3.886e-15 0.30
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 9.482e-13 0.39
CAH14_HUMAN CA14 Carbonic anhydrase 14 5.082e-12 0.36
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 5.511e-12 0.29
LYPA2_HUMAN LYPLA2 Acyl-protein thioesterase 2 1.133e-11 0.28
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 2.513e-11 0.35
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 9.455e-11 0.29
OX1R_HUMAN HCRTR1 Orexin receptor type 1 1.039e-10 0.40
LYPA1_HUMAN LYPLA1 Acyl-protein thioesterase 1 1.272e-10 0.28
ACES_HUMAN ACHE Acetylcholinesterase 1.613e-10 0.36
NU4M_HUMAN MT-ND4 NADH-ubiquinone oxidoreductase chain 4 4.72e-10 0.29
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 8.577e-10 0.28
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 2.937e-09 0.35
CHLE_HORSE BCHE Cholinesterase 3.488e-09 0.36
OX2R_HUMAN HCRTR2 Orexin receptor type 2 3.866e-09 0.40
KCNN1_HUMAN KCNN1 Small conductance calcium-activated potassium channel protein 1 4.099e-09 0.28
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 8.969e-09 0.41
KCNN3_RAT Kcnn3 Small conductance calcium-activated potassium channel protein 3 1.47e-08 0.82
KCNN2_HUMAN KCNN2 Small conductance calcium-activated potassium channel protein 2 1.149e-07 0.28
MIP_LEGPN mip Outer membrane protein MIP 2.322e-07 0.31
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 3.409e-07 0.33
ACPM_BOVIN NDUFAB1 Acyl carrier protein, mitochondrial 3.901e-07 0.33
NDUV1_BOVIN NDUFV1 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 3.901e-07 0.33
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 1.017e-06 0.33
ACES_ELEEL ache Acetylcholinesterase 1.331e-06 0.36
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 1.771e-06 0.30
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 6.48e-06 0.30
Q8WQX9_9TRYP PDEB1 Phosphodiesterase 6.794e-06 0.30
CAH9_HUMAN CA9 Carbonic anhydrase 9 7.859e-06 0.37
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 7.965e-06 0.30

Flurazepam

PRIO_MOUSE Prnp Major prion protein 7.101e-36 0.28
AURKA_MOUSE Aurka Aurora kinase A 1.851e-32 0.39
MK08_RAT Mapk8 Mitogen-activated protein kinase 8 1.51e-30 0.29
DRD1_HUMAN DRD1 D(1A) dopamine receptor 4.544e-27 0.35
PD2R2_MOUSE Ptgdr2 Prostaglandin D2 receptor 2 1.145e-24 0.32
MYT1_HUMAN MYT1 Myelin transcription factor 1 2.847e-23 0.29
CCKAR_RAT Cckar Cholecystokinin receptor type A 1.664e-19 0.39
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 2.22e-16 0.40
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 2.895e-11 0.51
CALM_BOVIN CALM Calmodulin 1.309e-10 0.28
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 3.291e-10 0.34
TSPO_RAT Tspo Translocator protein 1.085e-09 0.51
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 1.982e-09 0.35
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 2.148e-09 0.35
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 4.155e-09 0.28
GBRG2_HUMAN GABRG2 Gamma-aminobutyric acid receptor subunit gamma-2 1.278e-08 0.49
DRD2_HUMAN DRD2 D(2) dopamine receptor 3.997e-08 0.38
CALM1_HUMAN CALM1 Calmodulin-1 4.521e-08 0.28
SRC_MOUSE Src Neuronal proto-oncogene tyrosine-protein kinase Src 6.226e-08 0.29
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 1.887e-07 0.49
GBRB3_HUMAN GABRB3 Gamma-aminobutyric acid receptor subunit beta-3 1.974e-07 0.38
TAT_HV112 tat Protein Tat 9.298e-07 0.30
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 9.396e-07 0.29
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 1.228e-06 0.30
GBRA4_HUMAN GABRA4 Gamma-aminobutyric acid receptor subunit alpha-4 1.834e-06 0.31
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 1.858e-06 0.28
ACES_ELEEL ache Acetylcholinesterase 2.052e-06 0.39
GBRA3_HUMAN GABRA3 Gamma-aminobutyric acid receptor subunit alpha-3 2.402e-06 0.38
ALDH2_HUMAN ALDH2 Aldehyde dehydrogenase, mitochondrial 6.57e-06 0.35
DRD5_HUMAN DRD5 D(1B) dopamine receptor 7.55e-06 0.31
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 8.279e-06 0.28
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 9.348e-06 0.30

Pentosan_polysulfate

FGF1_HUMAN FGF1 Fibroblast growth factor 1 4.404e-26 0.31
FGF2_HUMAN FGF2 Fibroblast growth factor 2 1.188e-07 0.31

Esomeprazole

PEBB_HUMAN CBFB Core-binding factor subunit beta 1.322e-25 0.36
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 5.864e-25 0.33
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 7.086e-23 0.34
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 9.702e-23 0.44
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 2.859e-12 0.52
DDAH1_HUMAN DDAH1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 4.416e-12 0.44
TRAP1_HUMAN TRAP1 Heat shock protein 75 kDa, mitochondrial 1.537e-11 0.33
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 4.757e-10 0.33
ALKB3_HUMAN ALKBH3 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 4.162e-08 0.32
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 6.444e-08 0.29
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 1.149e-07 0.28
Q25615_ONCVO Chitinase 2.804e-07 0.31
ENPL_CANLF HSP90B1 Endoplasmin 4.303e-06 0.33

Tizanidine

G3HDX1_CRIGR Alpha-1B adrenergic receptor 3.131e-25 0.49
NISCH_RAT Nisch Nischarin 4.754e-19 0.37
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 1.79e-10 0.35
PI2R_HUMAN PTGIR Prostacyclin receptor 2.151e-10 0.40
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 1.031e-07 0.49
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.684e-06 0.49
ADA2B_RAT Adra2b Alpha-2B adrenergic receptor 2.453e-06 0.34
NISCH_HUMAN NISCH Nischarin 6.501e-06 0.49

Magnesium_sulfate

Q9HVB9_PSEAE Carbonic anhydrase 6.741e-19 0.30
CAH_METTE Carbonic anhydrase 3.933e-06 0.30

Pralidoxime

CLAT_HUMAN CHAT Choline O-acetyltransferase 1.073e-17 0.42
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 1.898e-13 0.46
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.994e-07 0.28
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 2.07e-06 0.28

Diethylcarbamazine

GNAI1_HUMAN GNAI1 Guanine nucleotide-binding protein G(i) subunit alpha-1 6.128e-13 0.32
GNAI3_HUMAN GNAI3 Guanine nucleotide-binding protein G(i) subunit alpha 2.246e-12 0.30
PAOX_HUMAN PAOX Peroxisomal N(1)-acetyl-spermine/spermidine oxidase 1.165e-11 0.34
RYR2_HUMAN RYR2 Ryanodine receptor 2 6.853e-11 0.43
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.976e-10 0.35
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 1.319e-08 0.36
HRH4_HUMAN HRH4 Histamine H4 receptor 1.413e-08 0.33
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 5.332e-08 0.35
ACHA4_MOUSE Chrna4 Neuronal acetylcholine receptor subunit alpha-4 6.707e-07 0.29

Metaxalone

Q9WJQ2_9HIV1 reverse transcriptase Reverse transcriptase protein 7.637e-09 0.32
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 1.578e-06 0.29
ATAD2_HUMAN ATAD2 ATPase family AAA domain-containing protein 2 1.759e-06 0.29
GRM2_HUMAN GRM2 Metabotropic glutamate receptor 2 1.966e-06 0.39

Dexmedetomidine

PPGB_HUMAN CTSA Lysosomal protective protein 1.043e-08 0.34
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 1.229e-08 0.31
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 2.232e-08 0.58
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.126e-06 0.33