Results of Job: search_fff34861-06e9-45ae-9bf8-d48ee9daf233

Query Target Key Target Name Description P-Value MaxTC

Taurolithocholic acid

GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 2.833e-74 1.00
EPHA2_MOUSE Epha2 Ephrin type-A receptor 2 2.006e-115 0.65
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.418e-104 0.49
SIA4B_RAT St3gal2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 2.571e-98 0.52
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 1.415e-93 0.67
AT12A_HUMAN ATP12A Potassium-transporting ATPase alpha chain 2 5.371e-69 0.34
CAH4_BOVIN CA4 Carbonic anhydrase 4 1.252e-68 0.69
SMT1_ARATH SMT1 Cycloartenol-C-24-methyltransferase 6.515e-67 0.38
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 3.359e-63 0.78
NTCP_RAT Slc10a1 Sodium/bile acid cotransporter 3.659e-59 0.67
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 1.075e-51 0.46
DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 4.095e-48 0.43
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 7.97e-46 0.49
AT1A1_CANLF ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 4.742e-44 0.32
NTCP2_HUMAN SLC10A2 Ileal sodium/bile acid cotransporter 2.348e-41 0.79
CDC45_HUMAN CDC45 Cell division control protein 45 homolog 1.921e-39 0.31
GBRA4_RAT Gabra4 Gamma-aminobutyric acid receptor subunit alpha-4 5.492e-37 0.31
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 1.925e-33 0.42
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 2.356e-33 0.34
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 2.804e-31 0.46
CD4_HUMAN CD4 T-cell surface glycoprotein CD4 1.061e-30 0.38
CP125_MYCTU cyp125 Steroid C26-monooxygenase 1.181e-29 0.37
CRYAB_HUMAN CRYAB Alpha-crystallin B chain 1.162e-28 0.35
DHCR7_RAT Dhcr7 7-dehydrocholesterol reductase 2.814e-28 0.36
NR1H4_HUMAN NR1H4 Bile acid receptor 6.822e-27 0.79
SHBG_RAT Shbg Sex hormone-binding globulin 7.184e-26 0.32
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.283e-25 0.69
CAH1_HUMAN CA1 Carbonic anhydrase 1 2.458e-25 0.69
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 1.501e-24 0.39
NMDE3_HUMAN GRIN2C Glutamate receptor ionotropic, NMDA 2C 1.61e-23 0.38
ABCBB_HUMAN ABCB11 Bile salt export pump 9.504e-23 0.57
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 4.122e-22 0.41
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 3.269e-21 0.47
REST_BORBU resT Telomere resolvase ResT 8.085e-21 0.52
NMDE4_HUMAN GRIN2D Glutamate receptor ionotropic, NMDA 2D 1.279e-19 0.38
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 2.036e-19 0.31
SO4C1_HUMAN SLCO4C1 Solute carrier organic anion transporter family member 4C1 1.006e-17 0.28
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.14e-17 0.46
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 3.991e-17 0.47
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 1.11e-16 0.50
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 1.11e-16 0.50
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.11e-16 0.38
VDR_HUMAN VDR Vitamin D3 receptor 3.331e-15 0.69
ANDR_RAT Ar Androgen receptor 4.33e-15 0.46
DPOLB_RAT Polb DNA polymerase beta 1.069e-13 0.69
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 2.424e-13 0.54
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 3.842e-13 0.51
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 4.728e-13 0.54
FGF1_HUMAN FGF1 Fibroblast growth factor 1 7.617e-13 0.44
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 1.617e-12 0.54
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 1.617e-12 0.54
GBRD_HUMAN GABRD Gamma-aminobutyric acid receptor subunit delta 3.865e-12 0.47
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 4.886e-12 0.54
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 2.119e-11 0.54
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 2.119e-11 0.54
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 3.136e-11 0.46
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 3.308e-11 0.54
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 5.065e-11 0.54
B4FS76_MAIZE 100281352 Delta(14)-sterol reductase 8.4e-11 0.29
Q2TU57_MAIZE Sterol-8,7-isomerase 8.4e-11 0.29
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 2.404e-10 0.42
RORA_HUMAN RORA Nuclear receptor ROR-alpha 2.802e-10 0.34
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 3.33e-10 0.54
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 7.255e-10 0.47
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 1.838e-09 0.47
ECR_DROME EcR Ecdysone receptor 2.268e-09 0.33
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 3.554e-09 0.54
LICH_HUMAN LIPA Lysosomal acid lipase/cholesteryl ester hydrolase 6.213e-09 0.32
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 2.288e-08 0.59
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 3.505e-08 0.34
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 4.357e-08 0.41
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 1.331e-07 0.35
ACES_TETCF ache Acetylcholinesterase 2.097e-06 0.38
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 5.563e-06 0.38
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 7.527e-06 0.36
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 9.158e-06 0.43

L-homoserine

CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.099e-116 0.48
BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 1.364e-102 0.45
GLN1B_ECOLI glnA Glutamine synthetase 1.497e-102 0.52
LUXS_BACSU luxS S-ribosylhomocysteine lyase 1.326e-83 0.37
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 1.093e-81 0.44
AAA1_RAT Slc7a10 Asc-type amino acid transporter 1 6.499e-75 0.60
GRM8_RAT Grm8 Metabotropic glutamate receptor 8 1.446e-74 0.52
GSH1_HUMAN GCLC Glutamate--cysteine ligase catalytic subunit 1.068e-72 0.41
GRIK5_HUMAN GRIK5 Glutamate receptor ionotropic, kainate 5 1.248e-72 0.35
GRM6_RAT Grm6 Metabotropic glutamate receptor 6 4.191e-69 0.52
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 2.411e-66 0.44
GRM8_MOUSE Grm8 Metabotropic glutamate receptor 8 4.819e-65 0.52
ARGI1_HUMAN ARG1 Arginase-1 1.408e-63 0.45
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 1.235e-58 0.44
ARGI2_HUMAN ARG2 Arginase-2, mitochondrial 3.404e-56 0.45
BHMT2_HUMAN BHMT2 S-methylmethionine--homocysteine S-methyltransferase BHMT2 2.374e-54 0.43
KYNU_HUMAN KYNU Kynureninase 6.61e-54 0.32
DHAS_HELPY asd Aspartate-semialdehyde dehydrogenase 3.751e-51 0.41
OTC_HUMAN OTC Ornithine carbamoyltransferase, mitochondrial 4.627e-48 0.38
GRM8_HUMAN GRM8 Metabotropic glutamate receptor 8 2.294e-46 0.52
LUXS_ECOLI luxS S-ribosylhomocysteine lyase 1.932e-45 0.36
LUXS_VIBCB luxS S-ribosylhomocysteine lyase 1.932e-45 0.36
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 3.8e-44 0.52
GRIA1_HUMAN GRIA1 Glutamate receptor 1 1.18e-43 0.35
GRIK2_HUMAN GRIK2 Glutamate receptor ionotropic, kainate 2 3.249e-43 0.44
GFPT1_HUMAN GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 1.399e-42 0.38
GRIA2_RAT Gria2 Glutamate receptor 2 2.973e-39 0.32
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 1.144e-38 0.31
TY3H_RAT Th Tyrosine 3-monooxygenase 1.381e-38 0.31
GRIA1_MOUSE Gria1 Glutamate receptor 1 1.285e-37 0.31
KYNU_RAT Kynu Kynureninase 1.443e-37 0.30
GSP_CRIFA GSP Glutathionylspermidine synthase 1.205e-36 0.33
ARGI1_RAT Arg1 Arginase-1 5.069e-36 0.45
GRIA3_RAT Gria3 Glutamate receptor 3 9.242e-34 0.35
GRIA4_HUMAN GRIA4 Glutamate receptor 4 1.468e-33 0.37
GRIK2_RAT Grik2 Glutamate receptor ionotropic, kainate 2 7.167e-33 0.44
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 1.462e-32 0.48
GRIA3_HUMAN GRIA3 Glutamate receptor 3 1.483e-32 0.31
GRIA4_RAT Gria4 Glutamate receptor 4 8.641e-29 0.31
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 2.97e-28 0.37
GSTK1_HUMAN GSTK1 Glutathione S-transferase kappa 1 5.245e-27 0.33
VGLU3_RAT Slc17a8 Vesicular glutamate transporter 3 2.649e-26 0.42
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 2.961e-26 0.52
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 7.913e-25 0.31
DAPE_HAEIN dapE Succinyl-diaminopimelate desuccinylase 4.212e-24 0.30
B9V8S1_XENLA grik2.L Ionotropic glutamate receptor subunit GluR6(Q) 5.518e-23 0.28
NOS3_BOVIN NOS3 Nitric oxide synthase, endothelial 2.015e-22 0.43
GRIA2_HUMAN GRIA2 Glutamate receptor 2 3.745e-21 0.35
SO4C1_HUMAN SLCO4C1 Solute carrier organic anion transporter family member 4C1 2.111e-20 0.33
NOS2_RAT Nos2 Nitric oxide synthase, inducible 1.708e-19 0.43
TY3H_HUMAN TH Tyrosine 3-monooxygenase 3.122e-19 0.31
AMPN_ECOLI pepN Aminopeptidase N 2.576e-18 0.29
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 1.882e-17 0.33
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 2.22e-16 0.45
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 7.772e-16 0.42
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.221e-15 0.30
GRIA1_RAT Gria1 Glutamate receptor 1 1.776e-15 0.31
GRIK3_HUMAN GRIK3 Glutamate receptor ionotropic, kainate 3 8.105e-15 0.35
NOS1_MOUSE Nos1 Nitric oxide synthase, brain 2.265e-14 0.41
NEP_MOUSE Mme Neprilysin 1.242e-13 0.30
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 2.482e-13 0.29
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 4.577e-13 0.48
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 7.9e-13 0.52
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 8.415e-12 0.33
AMPB_HUMAN RNPEP Aminopeptidase B 1.554e-11 0.31
PCNA_HUMAN PCNA Proliferating cell nuclear antigen 1.643e-11 0.32
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 2.703e-11 0.43
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 6.241e-11 0.33
Q6RY99_RAT Tetraspanin 6.878e-11 0.29
DDAH1_HUMAN DDAH1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 2.479e-10 0.37
Q9Z1J7_RAT Slc1a5 Amino acid transporter 5.982e-10 0.29
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 6.284e-10 0.43
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 1.126e-09 0.43
NOS1_RAT Nos1 Nitric oxide synthase, brain 1.628e-09 0.43
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 2.766e-09 0.30
DCOR_RAT Odc1 Ornithine decarboxylase 3.541e-08 0.32
DCOR_HUMAN ODC1 Ornithine decarboxylase 4.633e-08 0.30
AMPB_RAT Rnpep Aminopeptidase B 7.232e-08 0.32
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 1.853e-07 0.43
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 2.203e-07 0.34
CBPB1_PIG CPB1 Carboxypeptidase B 6.148e-07 0.28
PTPRA_HUMAN PTPRA Receptor-type tyrosine-protein phosphatase alpha 5.201e-06 0.33
AMPN_PIG ANPEP Aminopeptidase N 8.48e-06 0.37
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 8.644e-06 0.33

(R)-3-hydroxybutyrate

LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 2.792e-13 0.30
AMPB_RAT Rnpep Aminopeptidase B 3.205e-07 0.29

(S)-3-hydroxybutyrate

LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 2.792e-13 0.30
AMPB_RAT Rnpep Aminopeptidase B 3.205e-07 0.29